All Stories

  1. Crosstalk Between Endo/Exocytosis and Autophagy in Health and Disease
  2. Acyl-CoA-binding protein (ACBP): a phylogenetically conserved appetite stimulator
  3. 3,4‐Dimethoxychalcone induces autophagy through activation of the transcription factors TFE 3 and TFEB
  4. Acyl-CoA-Binding Protein Is a Lipogenic Factor that Triggers Food Intake and Obesity
  5. Moderation of neural excitation promotes longevity
  6. Synaptic vesicle fusion is modulated through feedback inhibition by dopamine auto‐receptors
  7. SUMOylation in Neurodegenerative Diseases
  8. Emerging Roles of Lipophagy in Health and Disease
  9. Mitochondrial maturation drives germline stem cell differentiation in Caenorhabditis elegans
  10. Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease
  11. Nucleophagy: from homeostasis to disease
  12. Maintenance of Proteostasis by P Body-Mediated Regulation of eIF4E Availability during Aging in Caenorhabditis elegans
  13. Hypoxia and Selective Autophagy in Cancer Development and Therapy
  14. Mechanisms of mitophagy in cellular homeostasis, physiology and pathology
  15. Small heat shock proteins and neurodegeneration: recent developments
  16. Regulation and Roles of Autophagy at Synapses
  17. The Role of Mitophagy in Innate Immunity
  18. Multimodal sensory processing in Caenorhabditis elegans
  19. Autophagy in Age-Associated Neurodegeneration
  20. Mitochondrial contributions to neuronal development and function
  21. Sex-specific regulation of aging in Caenorhabditis elegans
  22. Aspirin Recapitulates Features of Caloric Restriction
  23. Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
  24. Novel Insights Into the Anti-aging Role of Mitophagy
  25. The PMR1 pump in alpha-synuclein toxicity and neurodegeneration
  26. Demonstrating Improved Multiple Transport-Mean-Free-Path Imaging Capabilities of Light Sheet Microscopy in the Quantification of Fluorescence Dynamics
  27. In Vitro and In Vivo Detection of Mitophagy in Human Cells, C. Elegans, and Mice
  28. Mitophagy and age-related pathologies: Development of new therapeutics by targeting mitochondrial turnover
  29. Mitophagy in neurodegeneration and aging
  30. A Brief History of Cocaine
  31. Differential adiponectin signalling couples ER stress with lipid metabolism to modulate ageing in C. elegans
  32. Modulation of Autophagy by BDNF Underlies Synaptic Plasticity
  33. Molecular definitions of autophagy and related processes
  34. Small heat shock proteins in ageing and age-related diseases
  35. The role of SUMOylation in ageing and senescent decline
  36. Assessing Mitochondrial Selective Autophagy in the Nematode Caenorhabditis elegans
  37. Monitoring Autophagic Responses in Caenorhabditis elegans
  38. Generation of Caenorhabditis elegans Transgenic Animals by DNA Microinjection
  39. In vivo Mitophagy Monitoring in Caenorhabditis elegans to Determine Mitochondrial Homeostasis
  40. P-body and Stress Granule Quantification in Caenorhabditis elegans
  41. Protein Synthesis Rate Assessment by Fluorescence Recovery after Photobleaching (FRAP)
  42. The Role of Autophagy in Aging
  43. Autophagy and the endo/exosomal pathways in health and disease
  44. Selective and differential interactions of BNN27, a novel C17-spiroepoxy steroid derivative, with TrkA receptors, regulating neuronal survival and differentiation
  45. 18α-Glycyrrhetinic Acid Proteasome Activator Decelerates Aging and Alzheimer's Disease Progression in Caenorhabditis elegans and Neuronal Cultures
  46. Ectopic fat deposition contributes to age-associated pathology in Caenorhabditis elegans
  47. Stage dependent nutritional regulation of transgenerational longevity
  48. Differential Protein Distribution between the Nucleus and Mitochondria: Implications in Aging
  49. Mitochondrial biogenesis and clearance: a balancing act
  50. Erratum
  51. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
  52. Multiphoton Fluorescence Light Microscopy
  53. Mitochondria, autophagy and age-associated neurodegenerative diseases: New insights into a complex interplay
  54. In vivo imaging of mitophagy in Caenorhabditis elegans
  55. Balancing mitochondrial biogenesis and mitophagy to maintain energy metabolism homeostasis
  56. Protein synthesis as an integral quality control mechanism during ageing
  57. FAH Domain Containing Protein 1 (FAHD-1) Is Required for Mitochondrial Function and Locomotion Activity in C. elegans
  58. Non-linear imaging techniques visualize the lipid profile of C. elegans
  59. Interfacing mitochondrial biogenesis and elimination to enhance host pathogen defense and longevity
  60. Iron-Starvation-Induced Mitophagy Mediates Lifespan Extension upon Mitochondrial Stress in C. elegans
  61. Coupling mitogenesis and mitophagy for longevity
  62. Mitophagy: In sickness and in health
  63. A Customized Light Sheet Microscope to Measure Spatio-Temporal Protein Dynamics in Small Model Organisms
  64. Imaging ectopic fat deposition incaenorhabditis elegansmuscles using nonlinear microscopy
  65. Coordination of mitophagy and mitochondrial biogenesis during ageing in C. elegans
  66. Novel inducers of BECN1-independent autophagy:cis-unsaturated fatty acids
  67. Unsaturated fatty acids induce non-canonical autophagy
  68. Stress Responses During Ageing: Molecular Pathways Regulating Protein Homeostasis
  69. Autophagy in the physiology and pathology of the central nervous system
  70. Caenorhabditis elegans as a model for cancer research
  71. Proteasome activation as anti-aging and anti-aggregation strategy
  72. Spermidine protects against α-synuclein neurotoxicity
  73. Optical projection tomography and light sheet microscopy for imaging in biological specimens a comparison study
  74. Enhanced proteasome degradation extends Caenorhabditis elegans lifespan and alleviates aggregation-related pathologies
  75. Essential versus accessory aspects of cell death: recommendations of the NCCD 2015
  76. Mitochondrial homeostasis: The interplay between mitophagy and mitochondrial biogenesis
  77. Longevity pathways and memory aging
  78. Cellular and molecular longevity pathways: the old and the new
  79. Label-Free Imaging of Lipid Depositions in C. elegans Using Third-Harmonic Generation Microscopy
  80. Necrotic Cell Death in Caenorhabditis elegans
  81. Necrotic Cell Death in Caenorhabditis elegans
  82. Crosstalk between apoptosis, necrosis and autophagy
  83. Endonuclease G mediates α-synuclein cytotoxicity during Parkinson's disease
  84. Oxidative stress and mitochondrial protein quality control in aging
  85. Corrigendum to “Autophagy induction extends lifespan and reduces lipids content in response to frataxin silencing in C. elegans” [Exp. Gerontol. 48 (2013) 191–201]
  86. Enhanced proteasome degradation extendsCaenorhabditis elegans lifespan and amelioratesneurodegeneration
  87. Anthranilate Fluorescence Marks a Calcium-Propagated Necrotic Wave That Promotes Organismal Death in C. elegans
  88. The nucleotide-binding proteins Nubp1 and Nubp2 are negative regulators of ciliogenesis
  89. Mitochondrial Biogenesis and Dynamics in Neurodegeneration: A Causative Relationship
  90. Autophagy induction extends lifespan and reduces lipid content in response to frataxin silencing in C. elegans
  91. Spermidine promotes mating and fertilization efficiency in model organisms
  92. The contactin RIG-6 mediates neuronal and non-neuronal cell migration in Caenorhabditis elegans
  93. Metabolic Control by Target of Rapamycin and Autophagy during Ageing - A Mini-Review
  94. GPA-14, a Gαi subunit mediates dopaminergic behavioral plasticity in C. elegans
  95. Autophagy and ageing: Insights from invertebrate model organisms
  96. Heat shock response and ionstasis: axis against neurodegeneration
  97. The Ca2+/Mn2+ ion-pump PMR1 links elevation of cytosolic Ca2+ levels to α-synuclein toxicity in Parkinson’s disease models
  98. High-Throughput and Longitudinal Analysis of Aging and Senescent Decline in Caenorhabditis elegans
  99. Assessing Aging and Senescent Decline in Caenorhabditis elegans: Cohort Survival Analysis
  100. Small heat-shock proteins protect from heat-stroke-associated neurodegeneration
  101. Embryonic and induced pluripotent stem cell differentiation as a tool in neurobiology
  102. Downregulation of lung mitochondrial prohibitin in COPD
  103. Automated Motion Correction for In Vivo Optical Projection Tomography
  104. Necrotic cell death and neurodegeneration
  105. Multiphoton Fluorescence Light Microscopy
  106. The second international conference "genetics of aging and longevity"
  107. Guidelines for the use and interpretation of assays for monitoring autophagy
  108. Mitophagy in neurodegeneration and aging
  109. Calcium homeostasis in aging neurons
  110. Endocytosis and intracellular trafficking contribute to necrotic neurodegeneration inC. elegans
  111. Generalized matrix models and AGT correspondence at all genera
  112. Longevity-relevant regulation of autophagy at the level of the acetylproteome
  113. Cellular stress response pathways and ageing: intricate molecular relationships
  114. Microscopic Optical Projection Tomography In Vivo
  115. The role of autophagy in genetic pathways influencing ageing
  116. Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome
  117. KIT receptor activation by autocrine and paracrine stem cell factor stimulates growth of merkel cell carcinoma in vitro
  118. Cell tracking in live Caenorhabditis elegans embryos via third harmonic generation imaging microscopy measurements
  119. Opposing function of mitochondrial prohibitin in aging
  120. Modeling human diseases in Caenorhabditis elegans
  121. Molecular Modeling of Mechanosensory Ion Channel Structural and Functional Features
  122. Can autophagy promote longevity?
  123. Correction for specimen movement and rotation errors for in-vivo Optical Projection Tomography
  124. Imaging Caenorhabditis elegans embryogenesis by third-harmonic generation microscopy
  125. Non-apoptotic cell death in Caenorhabditis elegans
  126. Necrosis in yeast
  127. The life span-prolonging effect of Sirtuin-1 is mediated by autophagy
  128. Roles for SUMO Modification during Senescence
  129. Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy
  130. Protein Metabolism and Homeostasis in Aging
  131. Autophagy and Aging: Lessons from Progeria Models
  132. Autophagy and Longevity: Lessons from C. elegans
  133. Confronting Cellular Heterogeneity in Studies of Protein Metabolism and Homeostasis in Aging Research
  134. Mitochondrial Protein Quality Control Systems in Aging and Disease
  135. Post-Translational Modification of Cellular Proteins by Ubiquitin and Ubiquitin-Like Molecules: Role in Cellular Senescence and Aging
  136. Proteasome Function Determines Cellular Homeostasis and the Rate of Aging
  137. Protein Homeostasis in Models of Aging and Age-Related Conformational Disease
  138. Protein Metabolism and Lifespan in Caenorhabditis elegans
  139. Protein Synthesis and the Antagonistic Pleiotropy Hypothesis of Aging
  140. Regulation of Muscle Atrophy in Aging and Disease
  141. Regulation of Protein Turnover by Longevity Pathways
  142. Regulation of mRNA Translation as a Conserved Mechanism of Longevity Control
  143. Sensory Influence on Homeostasis and Lifespan: Molecules and Circuits
  144. Synthesis, Modification and Turnover of Proteins during Aging
  145. Autophagy mediates pharmacological lifespan extension by spermidineand resveratrol
  146. SUMOylation and cell signalling
  147. In vivo imaging of cell morphology and cellular processes in Caenorhabditis elegans, using non-linear phenomena
  148. The Genomes On Line Database (GOLD) in 2009: status of genomic and metagenomic projects and their associated metadata
  149. Prohibitin couples diapause signalling to mitochondrial metabolism during ageing in C. elegans
  150. Induction of autophagy by spermidine promotes longevity
  151. Prohibitin and mitochondrial biology
  152. Caspase-Independent Cell Death Mechanisms in Simple Animal Models
  153. Autophagy in Caenorhabditis elegans
  154. In vivo polarization dependant Second and Third harmonic generation imaging of Caenorhabditis elegans pharyngeal muscles
  155. The NemaGENETAG initiative: large scale transposon insertion gene-tagging in Caenorhabditis elegans
  156. Cell-Specific Monitoring of Protein Synthesis In Vivo
  157. Aging: Invertebrate Models of Normal Brain Aging
  158. Transgenesis in Caenorhabditis elegans
  159. 2 Common Aging Mechanisms: Energy Metabolism and Longevity in Caenorhabditis elegans
  160. Editorial: Brain Matters
  161. A synaptic DEG/ENaC ion channel mediates learning in C. elegans by facilitating dopamine signalling
  162. In vivo imaging of neurodegeneration in Caenorhabditis elegans by third harmonic generation microscopy
  163. The effects of p53 on whole organism longevity are mediated by autophagy
  164. In vivo imaging of cellular structures and processes in Caenorhabditis elegans, using non-linear microscopy
  165. Autophagy and cell death in model organisms
  166. A dual role of p53 in the control of autophagy
  167. Regulation of autophagy by cytoplasmic p53
  168. Ageing and the regulation of protein synthesis: a balancing act?
  169. Monitoring protein synthesis by fluorescence recovery after photobleaching (FRAP) in vivo
  170. No death without life: vital functions of apoptotic effectors
  171. Autophagy and Cell Death in Caenorhabditis elegans
  172. Mechanisms of aging and energy metabolism inCaenorhabditis elegans
  173. In vivo imaging of cellular structures in Caenorhabditis elegans by combined TPEF, SHG and THG microscopy
  174. The Genomes On Line Database (GOLD) in 2007: status of genomic and metagenomic projects and their associated metadata
  175. Protein Synthesis Is a Novel Determinant of Aging in Caenorhabditis elegans
  176. Autophagy is required for necrotic cell death in Caenorhabditis elegans
  177. In vivo imaging of anatomical features of the nematode Caenorhabditis elegans using non-linear (TPEF-SHG-THG) microscopy
  178. Protein Synthesis and Aging: eIF4E and the Soma vs. Germline Distinction
  179. Editorial: Diseases of the brain – neuronal function and dysfunction
  180. Functional and physical interaction between Bcl-XL and a BH3-like domain in Beclin-1
  181. Non-developmentally programmed cell death in Caenorhabditis elegans
  182. Cardiomyocyte necrosis: Alternative mechanisms, effective interventions
  183. eIF4E function in somatic cells modulates ageing in Caenorhabditis elegans
  184. Nemo: a computational tool for analyzing nematode locomotion
  185. Mechanosensitive Ion Channels in Caenorhabditis elegans
  186. Genome-wide investigation reveals pathogen-specific and shared signatures in the response of Caenorhabditis elegans to infection
  187. Caenorhabditis elegans: A versatile platform for drug discovery
  188. The role of synaptic ion channels in synaptic plasticity
  189. Signaling pathways regulating protein synthesis during ageing
  190. Lysosomal biogenesis and function is critical for necrotic cell death in Caenorhabditis elegans
  191. Germ line transformation of the olive fly Bactrocera oleae using a versatile transgenesis marker
  192. The Genomes On Line Database (GOLD) v.2: a monitor of genome projects worldwide
  193. First identification of a phosphorylcholine-substituted protein from Caenorhabditis elegans: isolation and characterization of the aspartyl protease ASP-6
  194. Imaging of Caenorhabditis elegans samples and sub-cellular localization of new generation photosensitizers for photodynamic therapy, using non-linear microscopy
  195. The Vacuolar H+-ATPase Mediates Intracellular Acidification Required for Neurodegeneration in C. elegans
  196. Proteolytic mechanisms in necrotic cell death and neurodegeneration
  197. Imaging of Caenorhabditis elegans neurons by second-harmonic generation and two-photon excitation fluorescence
  198. Neurodegenerative conditions associated with ageing: a molecular interplay?
  199. Genetic Models of Mechanotransduction: The Nematode Caenorhabditis elegans
  200. Calcium-dependent and aspartyl proteases in neurodegeneration and ageing in C. elegans
  201. The biochemistry of neuronal necrosis: rogue biology?
  202. Specific aspartyl and calpain proteases are required for neurodegeneration in C. elegans
  203. Death by necrosis
  204. Ageing research in Greece
  205. Induction of RNA interference in Caenorhabditis elegans by RNAs derived from plants exhibiting post-transcriptional gene silencing
  206. Eating less to live longer
  207. Interfering with RNA interference
  208. Caloric restriction and lifespan: a role for protein turnover?
  209. More neuropeptides in C. elegans
  210. Necrotic Cell Death in C. elegans Requires the Function of Calreticulin and Regulators of Ca2+ Release from the Endoplasmic Reticulum
  211. Structural and functional features of the intracellular amino terminus of DEG/ENaC ion channels
  212. Mechanotransduction in Caenorhabditis elegans: The Role of DEG/ENaC Ion Channels
  213. Acquisition of a potential marker for insect transformation: isolation of a novel alcohol dehydrogenase gene from Bactrocera oleae by functional complementation in yeast
  214. Heritable and inducible genetic interference by double-stranded RNA encoded by transgenes
  215. Caenorhabditis ElegansDegenerins and Vertebrate Enac Ion Channels Contain an Extracellular Domain Related to Venom Neurotoxins
  216. UNC-4/UNC-37-dependent repression of motor neuron-specific genes controls synaptic choice in Caenorhabditis elegans
  217. The SPFH domain: implicated in regulating targeted protein turnover in stomatins and other membrane-associated proteins
  218. Genetically targeted cell disruption in Caenorhabditis elegans
  219. MOLECULAR MODELING OF MECHANOTRANSDUCTION IN THE NEMATODE CAENORHABDITIS ELEGANS
  220. unc-8, a DEG/ENaC Family Member, Encodes a Subunit of a Candidate Mechanically Gated Channel That Modulates C. elegans Locomotion
  221. The DNA target sequence influences the dependence of the yeast transcriptional activator Gcn4 on co-factors
  222. Genetic evidence for functional specificity of the yeast GCN2 kinase
  223. Sequence Analysis of a 40·7 kb Segment from the Left Arm of Yeast Chromosome X Reveals 14 Known Genes and 13 New Open Reading Frames Including Homologues of Genes Clustered on the Right Arm of Chromosome XI
  224. Gene overexpression reveals alternative mechanisms that induce GCN4 mRNA translation
  225. Genetic evidence for functional specificity of the yeast GCN2 kinase
  226. Amplification and non-isotopic detection of specific DNA sequences in a single microtitre well
  227. A Transient GCN4 mRNA Destabilization Follows GCN4 Translational Derepression
  228. A recombinatorial method useful for cloning dominant alleles in Saccharomyces cerevisiae
  229. Transcriptional interference caused by GCN4 overexpression reveals multiple interactions mediating transcriptional activation
  230. Detection of anti-Rev antibodies in human immunodeficiency virus type-1 patients using a recombinant 18kD Rev protein
  231. The Role of DEG/ENaC Ion Channels in Sensory Mechanotransduction