All Stories

  1. Antipsychotic drugs counteract autophagy and mitophagy in multiple sclerosis
  2. Translational readthrough of GLA nonsense mutations suggests dominant-negative effects exerted by the interaction of wild-type and missense variants
  3. Mitochondrial calcium uniporter complex modulation in cancerogenesis
  4. High mitochondrial Ca2+ content increases cancer cell proliferation upon inhibition of mitochondrial permeability transition pore (mPTP)
  5. Mitochondrial permeability transition involves dissociation of F 1 F O ATP synthase dimers and C‐ring conformation
  6. Study of PTEN subcellular localization
  7. Mitochondria-Associated Membranes: Composition, Molecular Mechanisms, and Physiopathological Implications
  8. Shedding light on molecular mechanisms and identity of mPTP
  9. The P2X7 receptor directly interacts with the NLRP3 inflammasome scaffold protein
  10. Mitochondrial Ca2+-dependent NLRP3 activation exacerbates the Pseudomonas aeruginosa-driven inflammatory response in cystic fibrosis
  11. A novel Ca2+-mediated cross-talk between endoplasmic reticulum and acidic organelles: Implications for NAADP-dependent Ca2+ signalling
  12. p53 at the endoplasmic reticulum regulates apoptosis in a Ca 2+ -dependent manner
  13. A family with paroxysmal nonkinesigenic dyskinesias (PNKD): Evidence of mitochondrial dysfunction
  14. Molecular identity of the mitochondrial permeability transition pore and its role in ischemia-reperfusion injury
  15. Accelerated Tumor Progression in Mice Lacking the ATP Receptor P2X7
  16. The interplay between p66Shc, reactive oxygen species and cancer cell metabolism
  17. SEPN1, an endoplasmic reticulum-localized selenoprotein linked to skeletal muscle pathology, counteracts hyperoxidation by means of redox-regulating SERCA2 pump activity
  18. Efficacy of magnesium chloride in the treatment of Hailey-Hailey disease: from serendipity to evidence of its effect on intracellular Ca2+homeostasis
  19. The Mitochondrial Permeability Transition Pore and Cancer: Molecular Mechanisms Involved in Cell Death
  20. The RED light is on! New tools for monitoring Ca 2+ dynamics in the endoplasmic reticulum and mitochondria
  21. Selective Augmentation of Stem Cell Populations in Structural Fat Grafts for Maxillofacial Surgery
  22. Molecular Characterization of the Dominant-Negative Role of Cancer-Associated PTEN: Sometimes, Null is Better
  23. Mitochondria-Associated Endoplasmic Reticulum Membranes in Insulin Signaling
  24. Mitophagy and Mitochondrial Balance
  25. Novel insights into the mitochondrial permeability transition
  26. STAT3 Activities and Energy Metabolism: Dangerous Liaisons
  27. Silencing of mitochondrial Lon protease deeply alters mitochondrial proteome and functionality in RKO colorectal carcinoma cells
  28. The mitochondrial permeability transition pore is a dispensable element for mitochondrial calcium efflux
  29. A Unified Nomenclature and Amino Acid Numbering for Human PTEN
  30. Oncogenic and oncosuppressive signal transduction at mitochondria-associated endoplasmic reticulum membranes
  31. Amyloid-Beta Disrupts Calcium and Redox Homeostasis in Brain Endothelial Cells
  32. Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition
  33. The endoplasmic reticulum–mitochondria connection: One touch, multiple functions
  34. Cancer-Associated PTEN Mutants Act in a Dominant-Negative Manner to Suppress PTEN Protein Function
  35. Tumor necrosis factor-α impairs oligodendroglial differentiation through a mitochondria-dependent process
  36. The mitochondrial calcium uniporter complex: molecular components, structure and physiopathological implications
  37. Altering mitochondrial properties
  38. Isolation of plasma membrane–associated membranes from rat liver
  39. Methods to Monitor and Compare Mitochondrial and Glycolytic ATP Production
  40. Methods to Monitor ROS Production by Fluorescence Microscopy and Fluorometry
  41. Differential expression of microRNA501-5p affects the aggressiveness of clear cell renal carcinoma
  42. Transglutaminase 2 Contributes to Apoptosis Induction in Jurkat T Cells by Modulating Ca2+ Homeostasis via Cross-Linking RAP1GDS1
  43. Perturbed mitochondrial Ca2+signals as causes or consequences of mitophagy induction
  44. Berberine slows cell growth in autosomal dominant polycystic kidney disease cells
  45. Subcellular calcium measurements in mammalian cells using jellyfish photoprotein aequorin-based probes
  46. PRKCB/protein kinase C, beta and the mitochondrial axis as key regulators of autophagy
  47. 17β-Estradiol Enhances Signalling Mediated by VEGF-A-Delta-Like Ligand 4-Notch1 Axis in Human Endothelial Cells
  48. Identification of PTEN at the ER and MAMs and its regulation of Ca2+ signaling and apoptosis in a protein phosphatase-dependent manner
  49. Mitochondrial calcium uniporter, MiRNA and cancer
  50. Nanotechnology to drive stem cell commitment
  51. Role of the c subunit of the FOATP synthase in mitochondrial permeability transition
  52. Hyaluronic Acid Induces Activation of the κ-Opioid Receptor
  53. Chemoresistance and Cancer-Related Inflammation: Two Hallmarks of Cancer Connected by an Atypical Link, PKCζ
  54. Downregulation of the Mitochondrial Calcium Uniporter by Cancer-Related miR-25
  55. Oxidative Stress in Cardiovascular Diseases and Obesity: Role of p66Shc and Protein Kinase C
  56. Cardiac mitochondrial dysfunction during hyperglycemia—The role of oxidative stress and p66Shc signaling
  57. Disrupted ATP synthase activity and mitochondrial hyperpolarisation-dependent oxidative stress is associated with p66Shc phosphorylation in fibroblasts of NARP patients
  58. Donor Age-Related Biological Properties of Human Dental Pulp Stem Cells Change in Nanostructured Scaffolds
  59. The mitochondrial heme exporter FLVCR1b mediates erythroid differentiation
  60. Guanosine diphosphate exerts a lower effect on superoxide release from mitochondrial matrix in the brains of uncoupling protein-2 knockout mice: New evidence for a putative novel function of uncoupling proteins as superoxide anion transporters
  61. The prolyl-isomerase Pin1 activates the mitochondrial death program of p53
  62. Mitochondrial Ca2+ and apoptosis
  63. Ero1α Regulates Ca 2+ Fluxes at the Endoplasmic Reticulum–Mitochondria Interface (MAM)
  64. Selective modulation of subtype III IP3R by Akt regulates ER Ca2+ release and apoptosis
  65. ATP synthesis and storage
  66. In Vitro Concurrent Endothelial and Osteogenic Commitment of Adipose-Derived Stem Cells and Their Genomical Analyses Through Comparative Genomic Hybridization Array: Novel Strategies to Increase the Successful Engraftment of Tissue-Engineered Bone Grafts
  67. STAT3 can serve as a hit in the process of malignant transformation of primary cells
  68. Systemic Elevation of PTEN Induces a Tumor-Suppressive Metabolic State
  69. The selective inhibition of nuclear PKCζ restores the effectiveness of chemotherapeutic agents in chemoresistant cells
  70. Reactive Oxygen Species: Friends and Foes of Signal Transduction
  71. Adipose Tissue Regeneration: A State of the Art
  72. Mitochondria-Associated Membranes (MAMs) as Hotspot Ca2+ Signaling Units
  73. Mitochondrial calcium homeostasis as potential target for mitochondrial medicine
  74. Mitochondria-Ros Crosstalk in the Control of Cell Death and Aging
  75. High IGFBP2 Expression Correlates with Tumor Severity in Pediatric Rhabdomyosarcoma
  76. Hyaluronan and Fibrin Biomaterial as Scaffolds for Neuronal Differentiation of Adult Stem Cells Derived from Adipose Tissue and Skin
  77. Relation Between Mitochondrial Membrane Potential and ROS Formation
  78. p66Shc Aging Protein in Control of Fibroblasts Cell Fate
  79. Mitochondrial redox signalling by p66Shc mediates ALS-like disease through Rac1 inactivation
  80. VDAC1 selectively transfers apoptotic Ca2+ signals to mitochondria
  81. Vav1 is a crucial molecule in monocytic/macrophagic differentiation of myeloid leukemia-derived cells
  82. Mitochondrial Tolerance to Drugs and Toxic Agents in Ageing and Disease
  83. Mitochondria associated membranes (MAMs) as critical hubs for apoptosis
  84. The role of PML in the control of apoptotic cell fate: a new key player at ER–mitochondria sites
  85. PKC-β activation and pharmacologically induced weight gain during antipsychotic treatment
  86. Translocation of signalling proteins to the plasma membrane revealed by a new bioluminescent procedure
  87. Calcium signaling around Mitochondria Associated Membranes (MAMs)
  88. Protein Kinases and Phosphatases in the Control of Cell Fate
  89. Estrogen Receptor β Exerts Tumor Repressive Functions in Human Malignant Pleural Mesothelioma via EGFR Inactivation and Affects Response to Gefitinib
  90. PML Regulates Apoptosis at Endoplasmic Reticulum by Modulating Calcium Release
  91. Redox Control of Protein Kinase C: Cell- and Disease-Specific Aspects
  92. KRIT1 Regulates the Homeostasis of Intracellular Reactive Oxygen Species
  93. Mitochondria, calcium signaling and cell death by apoptosis and autophagy
  94. Oxidative stress-dependent p66Shc phosphorylation in skin fibroblasts of children with mitochondrial disorders
  95. Nanoscale particle therapies for wounds and ulcers
  96. Oxidative stress-dependent p66Shc phosphorylation in skin fibroblasts of children with mitochondrial disorders
  97. The p13 protein of human T cell leukemia virus type 1 (HTLV-1) modulates mitochondrial membrane potential and calcium uptake
  98. Functional and structural alterations in the endoplasmic reticulum and mitochondria during apoptosis triggered by C2-ceramide and CD95/APO-1/FAS receptor stimulation
  99. Plasma membrane associated membranes (PAM) from Jurkat cells contain STIM1 protein
  100. NF-κB activation is required for apoptosis in fibrocystin/polyductin-depleted kidney epithelial cells
  101. Isolation of mitochondria-associated membranes and mitochondria from animal tissues and cells
  102. Structural and functional link between the mitochondrial network and the endoplasmic reticulum
  103. Intramitochondrial calcium regulation by the FHIT gene product sensitizes to apoptosis
  104. Controlling metabolism and cell death: At the heart of mitochondrial calcium signalling
  105. Age-related changes in levels of p66Shc and serine 36-phosphorylated p66Shc in organs and mouse tissues
  106. Mitochondria, calcium and cell death: A deadly triad in neurodegeneration
  107. Expression of the P2X7 Receptor Increases the Ca2+ Content of the Endoplasmic Reticulum, Activates NFATc1, and Protects from Apoptosis
  108. Akt kinase reducing endoplasmic reticulum Ca2+ release protects cells from Ca2+-dependent apoptotic stimuli
  109. Calcium and apoptosis: ER-mitochondria Ca2+ transfer in the control of apoptosis
  110. S8.6 Role of peroxisomes in cell calcium homeostasis
  111. The versatility of mitochondrial calcium signals: From stimulation of cell metabolism to induction of cell death
  112. P/15 Mitochondrial Ca2+ homeostasis in cell life and death
  113. Novel role for polycystin-1 in modulating cell proliferation through calcium oscillations in kidney cells
  114. Endoplasmic Reticulum/Mitochondria Calcium Cross-Talk
  115. Regulation of autophagy by cytoplasmic p53
  116. Peroxisomes as Novel Players in Cell Calcium Homeostasis
  117. Ca2+ Signaling, Mitochondria and Cell Death
  118. p66Shc, oxidative stress and aging: Importing a lifespan determinant into mitochondria
  119. Endoplasmic reticulum stress and alteration in calcium homeostasis are involved in cadmium-induced apoptosis
  120. High glucose induces adipogenic differentiation of muscle-derived stem cells
  121. INTRACELLULAR EVALUATION OF ER TARGETING ELUCIDATES A MILD FORM OF INHERITED COAGULATION DEFICIENCY
  122. Protein Kinase C   and Prolyl Isomerase 1 Regulate Mitochondrial Effects of the Life-Span Determinant p66Shc
  123. Sphingosine 1-phosphate receptors modulate intracellular Ca2+ homeostasis
  124. Biosensors for the Detection of Calcium and pH
  125. Differential recruitment of PKC isoforms in HeLa cells during redox stress
  126. Mitochondria in Cell Life and Death
  127. Polycystin-1 promotes PKCα-mediated NF-κB activation in kidney cells
  128. Overexpression of adenine nucleotide translocase reduces Ca2+ signal transmission between the ER and mitochondria
  129. Intracellular readthrough of nonsense mutations by aminoglycosides in coagulation factor VII
  130. Electron Transfer between Cytochrome c and p66Shc Generates Reactive Oxygen Species that Trigger Mitochondrial Apoptosis
  131. The cytoplasmic C-terminus of polycystin-1 increases cell proliferation in kidney epithelial cells through serum-activated and Ca2+-dependent pathway(s)
  132. Metformin Prevents Glucose-Induced Protein Kinase C- 2 Activation in Human Umbilical Vein Endothelial Cells Through an Antioxidant Mechanism
  133. Aequorin chimeras as valuable tool in the measurement of Ca2+ concentration during cadmium injury
  134. Differential recruitment of PKC isoforms in HeLa cells during redox stress
  135. pH difference across the outer mitochondrial membrane measured with a green fluorescent protein mutant
  136. Bcl-2 and Bax Exert Opposing Effects on Ca2+ Signaling, Which Do Not Depend on Their Putative Pore-forming Region
  137. The Coxsackievirus 2B Protein Suppresses Apoptotic Host Cell Responses by Manipulating Intracellular Ca2+ Homeostasis
  138. Mitochondrial Ca2+ homeostasis in health and disease
  139. Chondrocyte protein with a poly-proline region (CHPPR) is a novel mitochondrial protein and promotes mitochondrial fission
  140. Calcium and apoptosis: facts and hypotheses
  141. Recombinant Expression of the Ca 2+ -sensitive Aspartate/Glutamate Carrier Increases Mitochondrial ATP Production in Agonist-stimulated Chinese Hamster Ovary Cells
  142. Expression of polycystin-1 C-terminal fragment enhances the ATP-induced Ca2+ release in human kidney cells
  143. Modulation of Calcium Homeostasis by the Endoplasmic Reticulum in Health and Disease
  144. Endoplasmic reticulum, Bcl-2 and Ca2+ handling in apoptosis
  145. A role for calcium in Bcl-2 action?
  146. Serca1 Truncated Proteins Unable to Pump Calcium Reduce the Endoplasmic Reticulum Calcium Concentration and Induce Apoptosis
  147. Recombinant aequorin and green fluorescent protein as valuable tools in the study of cell signalling
  148. Molecular machinery and signaling events in apoptosis
  149. Molecular machinery and signaling events in apoptosis
  150. Targeting of reporter molecules to mitochondria to measure calcium, ATP, and pH
  151. Measuring Ca2+ in the Nucleoplasm of Intact Cells
  152. Ca2+ Measurements in Mitochondria
  153. Recombinant aequorin as tool for monitoring calcium concentration in subcellular compartments
  154. Regulation of mitochondrial ATP synthesis by calcium: Evidence for a long-term metabolic priming
  155. Mitochondria as biosensors of calcium microdomains
  156. Targeted recombinant aequorins: Tools for monitoring [Ca2+] in the various compartments of a living cell
  157. Targeting, Expressing and Calibrating Recombinant Aequorin
  158. The Golgi apparatus is an inositol 1,4,5-trisphosphate-sensitive Ca2+ store, with functional properties distinct from those of the endoplasmic reticulum
  159. New light on mitochondrial calcium
  160. Chapter 5: Targeting GFP to Organelles