All Stories

  1. Radiation‑Induced Microglial Turnover Elicits a cGAS‑Mediated Interferon Response
  2. Unraveling microglial spatial organization in the developing human brain with DeepCellMap, a deep learning approach coupled with spatial statistics
  3. Rapid and robust isolation of microglia and vascular cells from brain subregions for integrative single-cell analyses
  4. Irradiation and lithium treatment alter the global DNA methylation pattern and gene expression underlying a shift from gliogenesis towards neurogenesis in human neural progenitors
  5. Irradiation and lithium treatment alter the global DNA methylation pattern and gene expression underlying a shift from gliogenesis towards neurogenesis in human neural progenitors
  6. Correction: Dying transplanted neural stem cells mediate survival bystander effects in the injured brain
  7. Dying transplanted neural stem cells mediate survival bystander effects in the injured brain
  8. Post-Compulsory Education in Teenagers and Young Adults Treated for Brain Tumors in Childhood: A Swedish Nationwide Registry-Based Study
  9. A cross‐sectional survey of moral distress and ethical climate – Situations in paediatric oncology care that involve children’s voices
  10. Optical Coherence Tomography Identifies Visual Pathway Involvement Earlier than Visual Function Tests in Children with MRI-Verified Optic Pathway Gliomas
  11. Radiobiological Evaluation of Combined Gamma Knife Radiosurgery and Hyperthermia for Pediatric Neuro-Oncology
  12. Umbilical cord-derived mesenchymal stromal cells immunomodulate and restore actin dynamics and phagocytosis of LPS-activated microglia via PI3K/Akt/Rho GTPase pathway
  13. Multifaceted microglia — key players in primary brain tumour heterogeneity
  14. Can National Tests from the Last Year of Compulsory School Be Used to Obtain More Detailed Information about Academic Performance in Children Treated for Brain Tumours? A Nationwide, Population-Based Study from Sweden
  15. Underestimated Peripheral Effects Following Pharmacological and Conditional Genetic Microglial Depletion
  16. Sex-Specific Effects of Microglia-Like Cell Engraftment during Experimental Autoimmune Encephalomyelitis
  17. Nationwide, population-based study of school grades in practical and aesthetic subjects of children treated for brain tumour
  18. Lithium treatment reverses irradiation-induced changes in rodent neural progenitors and rescues cognition
  19. A nationwide, population‐based study of school grades, delayed graduation, and qualification for school years 10‐12, in children with brain tumors in Sweden
  20. Hyperthermia Treatment Planning Including Convective Flow in Cerebrospinal Fluid for Brain Tumour Hyperthermia Treatment Using a Novel Dedicated Paediatric Brain Applicator
  21. The Secretome of Microglia Regulate Neural Stem Cell Function
  22. Language barriers and the use of professional interpreters in pediatric oncology.
  23. Development and evaluation of the Communication over Language Barriers questionnaire (CoLB-q) in paediatric healthcare
  24. A role for endothelial cells in radiation-induced inflammation
  25. A novel mouse model of radiation-induced cancer survivorship diseases of the gut
  26. Glioma-induced SIRT1-dependent activation of hMOF histone H4 lysine 16 acetyltransferase in microglia promotes a tumor supporting phenotype
  27. Hypothermia after cranial irradiation protects neural progenitor cells in the subventricular zone but not in the hippocampus
  28. Haploinsufficiency in the mitochondrial protein CHCHD4 reduces brain injury in a mouse model of neonatal hypoxia-ischemia
  29. Radiation induces progenitor cell death, microglia activation and blood-brain barrier damage in the juvenile rat cerebellum
  30. Lithium protects hippocampal progenitors, cognitive performance and hypothalamus–pituitary function after irradiation to the juvenile rat brain
  31. Inhibition of autophagy prevents irradiation-induced neural stem and progenitor cell death in the juvenile mouse brain
  32. Lithium Accumulates in Neurogenic Brain Regions as Revealed by High Resolution Ion Imaging
  33. Cranial irradiation induces transient microglia accumulation, followed by long-lasting inflammation and loss of microglia
  34. Glioma-induced inhibition of caspase-3 in microglia promotes a tumor-supportive phenotype
  35. Autophagy in acute brain injury
  36. Dichloroacetate treatment improves mitochondrial metabolism and reduces brain injury in neonatal mice
  37. C3 deficiency ameliorates the negative effects of irradiation of the young brain on hippocampal development and learning
  38. Active video gaming improves body coordination in survivors of childhood brain tumours
  39. Neuroprotection by selective neuronal deletion of Atg7 in neonatal brain injury
  40. Caspase inhibition impaired the neural stem/progenitor cell response after cortical ischemia in mice
  41. Towards better patient safety in otolaryngology: characteristics of patient injuries and their relationship with items on the WHO Surgical Safety Checklist
  42. Resident microglia, rather than blood-derived macrophages, contribute to the earlier and more pronounced inflammatory reaction in the immature compared with the adult hippocampus after hypoxia-ischemia
  43. Healthcare professionals' perceptions of the ethical climate in paediatric cancer care
  44. Irradiation of the Juvenile Brain Provokes a Shift from Long-Term Potentiation to Long-Term Depression
  45. Interaction between AIF and CHCHD4 Regulates Respiratory Chain Biogenesis
  46. Clarifying perspectives
  47. Microglia-Secreted Galectin-3 Acts as a Toll-like Receptor 4 Ligand and Contributes to Microglial Activation
  48. Administration of Umbilical Cord Blood Cells Transiently Decreased Hypoxic-Ischemic Brain Injury in Neonatal Rats
  49. Experiences of Ethical Issues When Caring for Children With Cancer
  50. How Patients Experience Antral Irrigation
  51. A template for writing radiotherapy protocols
  52. Transplantation of Enteric Neural Stem/Progenitor Cells into the Irradiated Young Mouse Hippocampus
  53. Essential versus accessory aspects of cell death: recommendations of the NCCD 2015
  54. Therapeutic Benefits of Delayed Lithium Administration in the Neonatal Rat after Cerebral Hypoxia-Ischemia
  55. The hippocampal neurovascular niche during normal development and after irradiation to the juvenile mouse brain
  56. Different reactions to irradiation in the juvenile and adult hippocampus
  57. Altered cognitive performance and synaptic function in the hippocampus of mice lacking C3
  58. Delayed, Long-Term Administration of the Caspase Inhibitor Q-VD-OPh Reduced Brain Injury Induced by Neonatal Hypoxia-Ischemia
  59. The association between sex-related interleukin-6 gene polymorphisms and the risk for cerebral palsy
  60. Lipopolysaccharide sensitized male and female juvenile brains to ionizing radiation
  61. Irradiation to the young mouse brain impaired white matter growth more in females than in males
  62. Loss of hippocampal neurogenesis, increased novelty-induced activity, decreased home cage activity, and impaired reversal learning one year after irradiation of the young mouse brain
  63. Anaesthetic neurotoxicity and neuroplasticity: an expert group report and statement based on the BJA Salzburg Seminar
  64. Brain development in rodents and humans: Identifying benchmarks of maturation and vulnerability to injury across species
  65. Effect of tonsillectomy on health-related quality of life and costs
  66. Grafting of neural stem and progenitor cells to the hippocampus of young, irradiated mice causes gliosis and disrupts the granule cell layer
  67. Irradiation to the Young Mouse Brain Caused Long-Term, Progressive Depletion of Neurogenesis but did not Disrupt the Neurovascular Niche
  68. Injury and Repair in the Immature Brain
  69. Lipopolysaccharide-Induced Inflammation Aggravates Irradiation-Induced Injury to the Young Mouse Brain
  70. Inhaled Nitric Oxide Protects Males But not Females from Neonatal Mouse Hypoxia–Ischemia Brain Injury
  71. Decreased oxidative stress during glycolytic inhibition enables maintenance of ATP production and astrocytic survival
  72. Lithium reduced neural progenitor apoptosis in the hippocampus and ameliorated functional deficits after irradiation to the immature mouse brain
  73. Sex-dependent differences in behavior and hippocampal neurogenesis after irradiation to the young mouse brain
  74. Combined inhibition of cell death induced by apoptosis inducing factor and caspases provides additive neuroprotection in experimental traumatic brain injury
  75. Estimated clinical benefit of protecting neurogenesis in the developing brain during radiation therapy for pediatric medulloblastoma
  76. Neuroprotection by the histone deacetylase inhibitor trichostatin A in a model of lipopolysaccharide-sensitised neonatal hypoxic-ischaemic brain injury
  77. Inhalation of Nitric Oxide Prevents Ischemic Brain Damage in Experimental Stroke by Selective Dilatation of Collateral Arterioles
  78. Apoptosis-inducing factor downregulation increased neuronal progenitor, but not stem cell, survival in the neonatal hippocampus after cerebral hypoxia-ischemia
  79. Biochemical and Molecular Biological Assessments of Neonatal Hypoxia–Ischemia: Cell Signaling
  80. Morphological Assessments of Neonatal Hypoxia–Ischemia: In Situ Cell Degeneration
  81. Role of apoptosis inducing factor (AIF) for hippocampal neuronal cell death following global cerebral ischemia in mice
  82. Lithium-Mediated Long-Term Neuroprotection in Neonatal Rat Hypoxia–Ischemia is Associated with Antiinflammatory Effects and Enhanced Proliferation and Survival of Neural Stem/Progenitor Cells
  83. Induction of ER stress in response to oxygen-glucose deprivation of cortical cultures involves the activation of the PERK and IRE-1 pathways and of caspase-12
  84. Unique gene expression patterns indicate microglial contribution to neural stem cell recovery following irradiation
  85. Developmental dysregulation of adult neurogenesis
  86. Learning and Activity after Irradiation of the Young Mouse Brain Analyzed in Adulthood Using Unbiased Monitoring in a Home Cage Environment
  87. Repeated exposure of the developing rat brain to magnetic resonance imaging did not affect neurogenesis, cell death or memory function
  88. Apoptosis-inducing factor deficiency decreases the proliferation rate and protects the subventricular zone against ionizing radiation
  89. Lithium reduces apoptosis and autophagy after neonatal hypoxia–ischemia
  90. Nuclear translocation and calpain-dependent reduction of Bcl-2 after neonatal cerebral hypoxia–ischemia
  91. Erythropoietin: not just about erythropoiesis
  92. Life with or without AIF
  93. The growth hormone secretagogue hexarelin increases cell proliferation in neurogenic regions of the mouse hippocampus
  94. A brain-specific isoform of mitochondrial apoptosis-inducing factor: AIF2
  95. Isoflurane Anesthesia Induced Persistent, Progressive Memory Impairment, Caused a Loss of Neural Stem Cells, and Reduced Neurogenesis in Young, but Not Adult, Rodents
  96. Irradiation to the immature brain attenuates neurogenesis and exacerbates subsequent hypoxic-ischemic brain injury in the adult
  97. Decreased cytogenesis in the granule cell layer of the hippocampus and impaired place learning after irradiation of the young mouse brain evaluated using the IntelliCage platform
  98. Stimulatory Effects of Thyroid Hormone on Brain Angiogenesis in vivo and in vitro
  99. NF-κB-dependent regulation of brain-derived neurotrophic factor in hippocampal neurons by X-linked inhibitor of apoptosis protein
  100. Erythropoietin Improved Neurologic Outcomes in Newborns With Hypoxic-Ischemic Encephalopathy
  101. Mitochondrial membrane permeabilization in neuronal injury
  102. Reduced Liver Injury and Cytokine Release After Transplantation of Preconditioned Intestines
  103. Effects of postnatal thyroid hormone deficiency on neurogenesis in the juvenile and adult rat
  104. Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes
  105. Differential Recovery of Neural Stem Cells in the Subventricular Zone and Dentate Gyrus After Ionizing Radiation
  106. Developmental Shift of Cyclophilin D Contribution to Hypoxic-Ischemic Brain Injury
  107. Systemic Hypothermia Induced within 10 Hours After Birth Improved Neurological Outcome in Newborns with Hypoxic-Ischemic Encephalopathy
  108. Irradiation-induced loss of microglia in the young brain
  109. Neural stem/progenitor cells transplanted into the hippocampus of young mice survive and normalize behavior changes induced by irradiation
  110. Causal Role of Apoptosis-Inducing Factor for Neuronal Cell Death Following Traumatic Brain Injury
  111. Differential effects on stem and progenitor cells in the subventricular zone and hippocampus after ionizing radiation
  112. Age-Dependent Regenerative Responses in the Striatum and Cortex after Hypoxia-Ischemia
  113. Voluntary running rescues adult hippocampal neurogenesis after irradiation of the young mouse brain
  114. Regulation of autophagy by cytoplasmic p53
  115. Proliferative and Protective Effects of Growth Hormone Secretagogues on Adult Rat Hippocampal Progenitor Cells
  116. Developing Postmitotic Mammalian Neurons In Vivo Lacking Apaf-1 Undergo Programmed Cell Death by a Caspase-Independent, Nonapoptotic Pathway Involving Autophagy
  117. X chromosome-linked inhibitor of apoptosis protein reduces oxidative stress after cerebral irradiation or hypoxia-ischemia through up-regulation of mitochondrial antioxidants
  118. X-linked inhibitor of apoptosis protein increases mitochondrial antioxidants through NF-κB activation
  119. Death effector activation in the subventricular zone subsequent to perinatal hypoxia/ischemia
  120. Failure to complete apoptosis following neonatal hypoxia–ischemia manifests as “continuum” phenotype of cell death and occurs with multiple manifestations of mitochondrial dysfunction in rodent forebrain
  121. Mitochondrial Cell Death Control in Familial Parkinson Disease
  122. Cyclophilin A participates in the nuclear translocation of apoptosis-inducing factor in neurons after cerebral hypoxia-ischemia
  123. Donor pretreatment with FK506 reduces reperfusion injury and accelerates intestinal graft recovery in rats
  124. Pathological apoptosis in the developing brain
  125. Antioxidant Status Alters Levels of Fas-Associated Death Domain-Like IL-1B-Converting Enzyme Inhibitory Protein following Neonatal Hypoxia-Ischemia
  126. Apoptosis-inducing factor is a major contributor to neuronal loss induced by neonatal cerebral hypoxia-ischemia
  127. Less Neurogenesis and Inflammation in the Immature than in the Juvenile Brain after Cerebral Hypoxia-Ischemia
  128. Transplantation of Preconditioned Intestinal Grafts is Associated With Lower Inflammatory Activation and Remote Organ Injury in Rats
  129. Neuroprotective properties of memantine in differentin vitroandin vivomodels of excitotoxicity
  130. Bcl-2 phosphorylation in the BH4 domain precedes caspase-3 activation and cell death after neonatal cerebral hypoxic–ischemic injury
  131. Different apoptotic mechanisms are activated in male and female brains after neonatal hypoxia-ischaemia
  132. Free radicals, mitochondria, and hypoxia–ischemia in the developing brain
  133. Intraischemic mild hypothermia prevents neuronal cell death and tissue loss after neonatal cerebral hypoxia-ischemia
  134. Apoptosis-Inducing Factor Triggered by Poly(ADP-Ribose) Polymerase and Bid Mediates Neuronal Cell Death after Oxygen-Glucose Deprivation and Focal Cerebral Ischemia
  135. Progenitor cell injury after irradiation to the developing brain can be modulated by mild hypothermia or hyperthermia
  136. FK506 Donor Pretreatment Improves Intestinal Graft Microcirculation and Morphology by Concurrent Inhibition of Early NF-κB Activation and Augmented HSP72 Synthesis
  137. Role of cathepsins and cystatins in patients with recurrent miscarriage
  138. IGF-I neuroprotection in the immature brain after hypoxia-ischemia, involvement of Akt and GSK3β?
  139. Age-dependent sensitivity of the developing brain to irradiation is correlated with the number and vulnerability of progenitor cells
  140. The influence of age on apoptotic and other mechanisms of cell death after cerebral hypoxia–ischemia
  141. The nonerythropoietic asialoerythropoietin protects against neonatal hypoxia-ischemia as potently as erythropoietin
  142. Irradiation-induced progenitor cell death in the developing brain is resistant to erythropoietin treatment and caspase inhibition
  143. Nitrosylation precedes caspase-3 activation and translocation of apoptosis-inducing factor in neonatal rat cerebral hypoxia-ischaemia
  144. X-linked inhibitor of apoptosis (XIAP) protein protects against caspase activation and tissue loss after neonatal hypoxia–ischemia
  145. The role of cathepsin B and cystatin C in the mechanisms of invasion by ovarian cancer
  146. Activation of ERK1/2 after neonatal rat cerebral hypoxia-ischaemia
  147. Involvement of apoptosis-inducing factor in neuronal death after hypoxia-ischemia in the neonatal rat brain
  148. Post-ischemic hypothermia-induced tissue protection and diminished apoptosis after neonatal cerebral hypoxia–ischemia
  149. Death mechanisms in status epilepticus-generated neurons and effects of additional seizures on their survival
  150. Both apoptosis and necrosis occur early after intracerebral grafting of ventral mesencephalic tissue: a role for protease activation
  151. Cyclosporin A prevents calpain activation despite increased intracellular calcium concentrations, as well as translocation of apoptosis-inducing factor, cytochrome c and caspase-3 activation in neurons exposed to transient hypoglycemia
  152. Mitochondria and ischemic reperfusion damage in the adult and in the developing brain
  153. Caspase-mediated death of newly formed neurons in the adult rat dentate gyrus following status epilepticus
  154. Neuroprotection by Selective Nitric Oxide Synthase Inhibition at 24 Hours After Perinatal Hypoxia-Ischemia
  155. Effects of Selective Nitric Oxide Synthase Inhibition on IGF-1, Caspases and Cytokines in a Newborn Piglet Model of Perinatal Hypoxia-Ischaemia
  156. Role of Calpain in Human Sperm Activated by Progesterone for Fertilization
  157. NMDA blockade attenuates caspase-3 activation and DNA fragmentation after neonatal hypoxia–ischemia
  158. Degradation of fodrin and MAP 2 after neonatal cerebral hypoxic-ischemia
  159. Calpain and calpastatin activity in the optic pathway
  160. Developmental changes of calpain and calpastatin in rabbit brain
  161. Cerebral Hypoxia—Ischemia in Neonatal Rats or Mice: A Model of Perinatal Brain Injury