All Stories

  1. Autophagy drives osteogenic differentiation of human gingival mesenchymal stem cells
  2. Amino acid response by Halofuginone in Cancer cells triggers autophagy through proteasome degradation of mTOR
  3. Ovarian cancer cell-derived lysophosphatidic acid induces glycolytic shift and cancer-associated fibroblast-phenotype in normal and peritumoral fibroblasts
  4. Autophagy-dependent toxicity of amino-functionalized nanoparticles in ovarian cancer cells
  5. Multifunctional Gd-based mesoporous silica nanotheranostic for anticancer drug delivery
  6. Dihydroartemisinin induces apoptosis and autophagy-dependent cell death in cholangiocarcinoma through a DAPK1-BECLIN1 pathway
  7. Resveratrol interrupts the pro-invasive communication between cancer associated fibroblasts and cholangiocarcinoma cells
  8. Lysophosphatidic Acid Induces Metabolic Reprogramming in Ovarian Cancer via a Pseudohypoxic Response
  9. The metabolic cross-talk between epithelial cancer cells and stromal fibroblasts in ovarian cancer progression: Autophagy plays a role
  10. The protein restriction mimetic Resveratrol is an autophagy inducer stronger than amino acid starvation in ovarian cancer cells
  11. Resveratrol protects neuronal-like cells expressing mutant Huntingtin from dopamine toxicity by rescuing ATG4-mediated autophagosome formation
  12. Raman Spectrometric Detection Methods for Early and Non-Invasive Diagnosis of Alzheimer’s Disease
  13. Dopamine exacerbates mutant Huntingtin toxicity via oxidative-mediated inhibition of autophagy in SH-SY5Y neuroblastoma cells: Beneficial effects of anti-oxidant therapeutics
  14. PTEN dephosphorylates AKT to prevent the expression of GLUT1 on plasmamembrane and to limit glucose consumption in cancer cells
  15. Resveratrol inhibits IL-6-induced ovarian cancer cell migration through epigenetic up-regulation of autophagy
  16. B34 Dopamine imbalance in huntington’s disease: when the inhibition of autophagy can lead to cell catastrophe
  17. Transcriptomic analysis of the autophagy machinery in crustaceans
  18. Coordinated Metabolic Changes and Modulation of Autophagy during Myogenesis
  19. The Role of Cathepsin D in the Pathogenesis of Human Neurodegenerative Disorders
  20. The fine tuning of metabolism, autophagy and differentiation during in vitro myogenesis
  21. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
  22. Report from the Second International Conference of Traditional and Complementary Medicine on Health 2015
  23. Publishing scientifically sound papers in Traditional and Complementary Medicine
  24. Overexpression of parkin rescues the defective mitochondrial phenotype and the increased apoptosis of Cockayne Syndrome A cells
  25. Bergamot polyphenol fraction prevents nonalcoholic fatty liver disease via stimulation of lipophagy in cafeteria diet-induced rat model of metabolic syndrome
  26. autophagy and neuroprotection
  27. The Potential for Plant Derivatives against Acrylamide Neurotoxicity
  28. Decreased BECN1 mRNA Expression in Human Breast Cancer is Associated With Estrogen Receptor-Negative Subtypes and Poor Prognosis
  29. NaGdF4 Nanoparticles Coated with Functionalised Ethylenediaminetetraacetic Acid as Versatile Probes for Dual Optical and Magnetic Resonance Imaging
  30. PTEN regulates plasma membrane expression of glucose transporter 1 and glucose uptake in thyroid cancer cells
  31. Turmeric Toxicity in A431 Epidermoid Cancer Cells Associates with Autophagy Degradation of Anti‐apoptotic and Anti‐autophagic p53 Mutant
  32. Epigenetic Control of Autophagy by MicroRNAs in Ovarian Cancer
  33. Single Amino Acid Arginine Deprivation Triggers Prosurvival Autophagic Response in Ovarian Carcinoma SKOV3
  34. Expression and Clinical Significance of the Autophagy Proteins BECLIN 1 and LC3 in Ovarian Cancer
  35. Autophagy and thyroid carcinogenesis: genetic and epigenetic links
  36. Protection from UVB Toxicity in Human Keratinocytes by Thailand Native Herbs Extracts
  37. Knockdown of cathepsin D in zebrafish fertilized eggs determines congenital myopathy
  38. Similarities and differences in the biogenesis, processing and lysosomal targeting between zebrafish and human pro-Cathepsin D: Functional implications
  39. Cathepsins: Getting in Shape for Lysosomal Proteolysis
  40. Involvement of autophagy in ovarian cancer: a working hypothesis
  41. Defective Autophagy in Parkinson’s Disease: Role of Oxidative Stress
  42. Dopamine induces apoptosis in APPswe-expressing Neuro2A cells following Pepstatin-sensitive proteolysis of APP in acid compartments
  43. Biocompatibility, endocytosis, and intracellular trafficking of mesoporous silica and polystyrene nanoparticles in ovarian cancer cells: effects of size and surface charge groups
  44. DNA damage response by single-strand breaks in terminally differentiated muscle cells and the control of muscle integrity
  45. Labeling and exocytosis of secretory compartments in RBL mastocytes by polystyrene and mesoporous silica nanoparticles
  46. Guidelines for the use and interpretation of assays for monitoring autophagy
  47. Thyroid incidentaloma identified by 18 F‐fluorodeoxyglucose positron emission tomography with CT (FDG‐PET/CT): clinical and pathological relevance
  48. Induced autophagy reduces virus output in dengue infected monocytic cells
  49. Chelation of Lysosomal Iron Protects Dopaminergic SH-SY5Y Neuroblastoma Cells from Hydrogen Peroxide Toxicity by Precluding Autophagy and Akt Dephosphorylation
  50. Knock-Down of Cathepsin D Affects the Retinal Pigment Epithelium, Impairs Swim-Bladder Ontogenesis and Causes Premature Death in Zebrafish
  51. Patented Biomarkers for the Early Detection of Ovarian Cancer
  52. Resveratrol Reduces the Invasive Growth and Promotes the Acquisition of a Long-Lasting Differentiated Phenotype in Human Glioblastoma Cells
  53. Patented Biomarkers for the Early Detection of Ovarian Cancer
  54. The dilemma: Does tissue expression of cathepsin D reflect tumor malignancy? The question: Does the assay truly mirror cathepsin D mis-function in the tumor?
  55. Autophagy-active beclin-1 correlates with favourable clinical outcome in non-Hodgkin lymphomas
  56. Inhibition of PI3k Class III–Dependent Autophagy Prevents Apoptosis and Necrosis by Oxidative Stress in Dopaminergic Neuroblastoma Cells
  57. Differential role of cathepsins B and L in autophagy-associated cell death induced by arsenic trioxide in U87 human glioblastoma cells
  58. Agonist monoclonal antibodies against HGF receptor protect cardiac muscle cells from apoptosis
  59. High Expression of Cathepsin D in Non-Hodgkin’s Lymphomas Negatively Impacts on Clinical Outcome
  60. Autophagy, lithium, and amyotrophic lateral sclerosis
  61. Chemotherapy drug response in ovarian cancer cells strictly depends on a cathepsin D‐Bax activation loop
  62. Photoactive Hybrid Nanomaterials: Indocyanine Immobilized in Mesoporous MCM-41 for “In-Cell” Bioimaging
  63. Correction for Fornai et al. , Lithium delays progression of amyotrophic lateral sclerosis
  64. Role of Autophagy during Methamphetamine Neurotoxicity
  65. Akt Induces Apoptosis in Neuroblastoma Cells Expressing a C98X Vasopressin Mutant Following Autophagy Suppression
  66. Prolactin Promotes the Secretion of Active Cathepsin D at the Basal Side of Rat Mammary Acini
  67. Suppression of autophagy precipitates neuronal cell death following low doses of methamphetamine
  68. Autophagy and amyotrophic lateral sclerosis: The multiple roles of lithium
  69. Autophagic-lysosomal perturbation enhances tau aggregation in transfectants with induced wild-type tau expression
  70. Lithium delays progression of amyotrophic lateral sclerosis
  71. A fast and simple method for simultaneous mixed site‐specific mutagenesis of a wide coding sequence
  72. Resveratrol-induced apoptosis depends on the lipid kinase activity of Vps34 and on the formation of autophagolysosomes
  73. The expression of prolactin and its cathepsin D-mediated cleavage in the bovine corpus luteum vary with the estrous cycle
  74. Cathepsin D–Bax death pathway in oxidative stressed neuroblastoma cells
  75. Folding, activity and targeting of mutated human cathepsin D that cannot be processed into the double-chain form
  76. Resveratrol induces cell death in colorectal cancer cells by a novel pathway involving lysosomal cathepsin D
  77. PI3K-dependent lysosome exocytosis in nitric oxide-preconditioned hepatocytes
  78. Prognostic significance of microvessel density and vascular endothelial growth factor expression in sinonasal carcinomas☆
  79. cFLIP expression correlates with tumour progression and patient outcome in non‐Hodgkin lymphomas of low grade of malignancy
  80. High yield synthesis and characterization of phosphorylated recombinant human procathepsin D expressed in mammalian cells
  81. Autophagy-dependent cell survival and cell death in an autosomal dominant familial neurohypophyseal diabetes insipidus in vitro model
  82. Autophagy is a prosurvival mechanism in cells expressing an autosomal dominant familial neurohypophyseal diabetes insipidus mutant vasopressin transgene
  83. Cathepsin D released by lactating rat mammary epithelial cells is involved in prolactin cleavage under physiological conditions
  84. Preconditioning-induced cytoprotection in hepatocytes requires Ca2+-dependent exocytosis of lysosomes
  85. Destination ‘Lysosome’: a target organelle for tumour cell killing?
  86. Endosomal-Lysosomal Proteolysis Mediates Death Signalling by TNFα, Not by Etoposide, in L929 Fibrosarcoma Cells: Evidence for an Active Role of Cathepsin D
  87. Increase in Ceramide Level Alters the Lysosomal Targeting of Cathepsin D prior to Onset of Apoptosis in HT-29 Colon Cancer Cells
  88. Lysosomal proteases as potential targets for the induction of apoptotic cell death in human neuroblastomas
  89. Expression of protein kinase C ?1 confers resistance to TNF?- and paclitaxel-induced apoptosis in HT-29 colon carcinoma cells
  90. Transformation by oncogenic ras‐p21 alters the processing and subcellular localization of the lysosomal protease cathepsin D
  91. Transformation by oncogenic ras-p21 alters the processing and subcellular localization of the lysosomal protease cathepsin D
  92. Regulation of rat hepatocyte protein kinase C ? isoenzymes by the lipid peroxidation product 4-hydroxy-2,3-nonenal: A signaling pathway to modulate vesicular transport of glycoproteins
  93. Lysosomal segregation of a mannose-rich glycoprotein imparted by the prosequence of myeloperoxidase
  94. Human and hamster procathepsin D, although equally tagged with mannose-6-phosphate, are differentially targeted to lysosomes in transfected BHK cells
  95. Differentiation-induced changes in the content, secretion, and subcellular distribution of lysosomal cathepsins in the human colon cancer HT-29 cell line
  96. Mis-sorting of procathepsin D in metastogenic tumor cells is not due to impaired synthesis of the phosphomannosyl signal
  97. Differential targeting and processing of procathepsin D in normal and transformed murine 3T3 fibroblasts
  98. Exposed Thiols Confer Localization in the Endoplasmic Reticulum by Retention Rather than Retrieval
  99. Synthesis, maturation and extracellular release of procathepsin D as influenced by cell proliferation or transformation
  100. Differentiation-dependent autophagy controls the fate of newly synthesized N-linked glycoproteins in the colon adenocarcinoma HT-29 cell line
  101. Localization and Processing of Glycosylphosphatidylinositol-Anchored Cathepsin D
  102. A Heterotrimeric G-protein Controls Autophagic Sequestration in the Human Colon Cancer Cell Line HT-29
  103. Altered intracellular processing and enhanced secretion of procathepsin D in a highly deviated rat hepatoma
  104. Effects of Calcitriol on the Biogenesis of a Lysosomal Protease in Monocytes from Patients with Renal Failure
  105. Role of monocytes in cryoglobulinemia-associated nephritis
  106. Serum and Intracellular Detection of Cytokines in Patients Undergoing Chronic Hemodialysis
  107. Differential segregation of human and hamster cathepsin D in transfected baby-hàmster kidney cells
  108. Altered transport and processing of cathepsin D in human tumour cells with metastatic phenotype
  109. Suppression of the ‘uncovering’ of mannose‐6‐phosphate residues in lysosomal enzymes in the presence of NH4Cl
  110. Brefeldin A Prevents Uncovering but not Phosphorylation of the Recognition Marker in Cathepsin D
  111. Regulation of Protein Degradation in Neoplastic Cells
  112. Characterization of cathepsin D in ascites hepatoma cells and in the liver of tumour-bearing animals*1
  113. Regulation of lysosomal cysteine-proteinase activities in 3T3 and SV-3T3 cells*
  114. The transport of soluble lysosomal hydrolases from the Golgi complex to lysosomes