All Stories

  1. Heparan sulfate is a clearance receptor for aberrant extracellular proteins
  2. TORC1, Tel1/Mec1, and Mpk1 regulate autophagy induction after DNA damage in budding yeast
  3. Identification of a factor controlling lysosomal homeostasis using a novel lysosomal trafficking probe
  4. Cucurbitacin B Exerts Antiaging Effects in Yeast by Regulating Autophagy and Oxidative Stress
  5. Phosphatase-dependent fluctuations in DNA-damage checkpoint activation at partially defective telomeres
  6. Reversible DNA damage checkpoint activation at the pre‐senescent stage in telomerase‐deficient cells of Saccharomyces cerevisiae
  7. A nuclear membrane-derived structure associated with Atg8 is involved in the sequestration of selective cargo, the Cvt complex, during autophagosome formation in yeast
  8. A substrate localization model for the selective regulation of TORC1 downstream pathways
  9. Forced lipophagy reveals that lipid droplets are required for early embryonic development in mouse
  10. Use of CK-548 and CK-869 as Arp2/3 complex inhibitors directly suppresses microtubule assembly both in vitro and in vivo
  11. Vacuole-mediated selective regulation of TORC1-Sch9 signaling following oxidative stress
  12. Dissection of ubiquitinated protein degradation by basal autophagy
  13. Peroxisome biogenesis: a novel inducible PEX19 splicing variant is involved in early stages of peroxisome proliferation
  14. Availability of Amino Acids Extends Chronological Lifespan by Suppressing Hyper-Acidification of the Environment in Saccharomyces cerevisiae
  15. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
  16. Parishin fromGastrodia elataExtends the Lifespan of Yeast via Regulation of Sir2/Uth1/TOR Signaling Pathway
  17. Dynamic relocation of the TORC1-Gtr1/2-Ego1/2/3 complex is regulated by Gtr1 and Gtr2
  18. A novel interplay between the Fanconi anemia core complex and ATR-ATRIP kinase during DNA cross-link repair
  19. A Steroidal Saponin from Ophiopogon japonicus Extends the Lifespan of Yeast via the Pathway Involved in SOD and UTH1
  20. The Role of Autophagy in Genome Stability through Suppression of Abnormal Mitosis under Starvation
  21. Anti-Aging Effects of Hesperidin onSaccharomyces cerevisiaeviaInhibition of Reactive Oxygen Species andUTH1Gene Expression
  22. Control of Telomeric DNA Replication: Genetics, Molecular Biology, and Physiology
  23. Ganodermasides C and D, Two New Anti-Aging Ergosterols from Spores of the Medicinal MushroomGanoderma lucidum
  24. Ganodermasides A and B, two novel anti-aging ergosterols from spores of a medicinal mushroom Ganoderma lucidum on yeast via UTH1 gene
  25. Cell Size Regulation during Telomere-Directed Senescence inSaccharomyces cerevisiae
  26. The Yeast Tor Signaling Pathway Is Involved in G2/M Transition via Polo-Kinase
  27. Dimerization of the ATRIP Protein through the Coiled-Coil Motif and Its Implication to the Maintenance of Stalled Replication Forks
  28. Late S Phase-Specific Recruitment of Mre11 Complex Triggers Hierarchical Assembly of Telomere Replication Proteins in Saccharomyces cerevisiae
  29. Amino-terminal domain of ATRIP contributes to intranuclear relocation of the ATR-ATRIP complex following DNA damage
  30. ATR-dependent phosphorylation of ATRIP in response to genotoxic stress
  31. Reciprocal Association of the Budding Yeast ATM-Related Proteins Tel1 and Mec1 with Telomeres In Vivo
  32. A novel allele of fission yeast rad11 that causes defects in DNA repair and telomere length regulation
  33. Fission yeast Rhp51 is required for the maintenance of telomere structure in the absence of the Ku heterodimer
  34. Competition between the Rad50 Complex and the Ku Heterodimer Reveals a Role for Exo1 in Processing Double-Strand Breaks but Not Telomeres
  35. A Novel Mitochondrial Carnitine-acylcarnitine Translocase Induced by Partial Hepatectomy and Fasting
  36. Loss of p27Kip1 accelerates DNA replication after partial hepatectomy in mice
  37. Progressive rearrangement of telomeric sequences added to both the ITR ends of the yeast linear pGKL plasmid
  38. Apg10p, a novel protein-conjugating enzyme essential for autophagy in yeast
  39. Schizosaccharomyces pombe stt3+ is a functional homologue ofSaccharomyces cerevisiae STT3 which regulates oligosaccharyltransferase activity
  40. Y'-Help1, a DNA Helicase Encoded by the Yeast Subtelomeric Y' Element, Is Induced in Survivors Defective for Telomerase
  41. Analyses of APG13 gene involved in autophagy in yeast, Saccharomyces cerevisiae
  42. Apg1p, a novel protein kinase required for the autophagic process in Saccharomyces cerevisiae
  43. TLP1: A Gene Encoding a Protein Component of Mammalian Telomerase Is a Novel Member of WD Repeats Family
  44. Structural and functional analyses of APG5 a gene involved in autophagy in yeast
  45. Novel System for Monitoring Autophagy in the Yeast Saccharomyces cerevisiae
  46. Genetic interaction between the Ras-CAMP pathway and the Dis2s1/Glc7 protein phosphatase in Saccharomyces cerevisiae
  47. Characterization of the MKS1 gene, a new negative regulator of the Ras-cyclic AMP pathway in Saccharomyces cerevislae
  48. Characterization of the cyrl-2 UGA mutation in Saccharomyces cerevisiae