Contact

All Stories

  1. Ataxin-2 in the hypothalamus at the crossroads between metabolism and clock genes

    Article • Journal of Molecular Endocrinology, January 2023, Bioscientifica

    Prof Claudia Cavadas

  2. The impact of insomnia on frailty and the hallmarks of aging

    Article • Aging Clinical and Experimental Research, December 2022, Springer Science + Business Media

    Prof Claudia Cavadas

  3. SIRT1 activation and its circadian clock control: a promising approach against (frailty in) neurodegenerative disorders

    Article • Aging Clinical and Experimental Research, October 2022, Springer Science + Business Media

    Prof Claudia Cavadas

  4. Peripheral biomarkers to diagnose obstructive sleep apnea in adults: A systematic review and meta-analysis

    Article • Sleep Medicine Reviews, August 2022, Elsevier

    Prof Claudia Cavadas

  5. SIRT2 Deficiency Exacerbates Hepatic Steatosis via a Putative Role of the ER Stress Pathway

    Article • International Journal of Molecular Sciences, June 2022, MDPI AG

    Prof Claudia Cavadas

  6. PET Imaging of the Neuropeptide Y System: A Systematic Review

    Article • Molecules, June 2022, MDPI AG

    Prof Claudia Cavadas

  7. A look on food intake and satiety: from humans to rodent models

    Article • Nutrition Reviews, February 2022, Oxford University Press (OUP)

    Prof Claudia Cavadas

  8. Skin senescence: mechanisms and impact on whole-body aging

    Article • Trends in Molecular Medicine, February 2022, Elsevier

    Prof Claudia Cavadas

  9. Blueberry Counteracts Prediabetes in a Hypercaloric Diet-Induced Rat Model and Rescues Hepatic Mitochondrial Bioenergetics

    Article • Nutrients, November 2021, MDPI AG

    Prof Claudia Cavadas

  10. Small-molecule modulators of the circadian clock: Pharmacological potentials in circadian-related diseases

    Article • Drug Discovery Today, July 2021, Elsevier

    Prof Claudia Cavadas

  11. PI3K/AKT/MTOR and ERK1/2-MAPK signaling pathways are involved in autophagy stimulation induced by caloric restriction or caloric restriction mimetics in cortical neurons

    Article • Aging, March 2021, Impact Journals, LLC

    Prof Claudia Cavadas

  12. Long-term continuous positive airway pressure treatment ameliorates biological clock disruptions in obstructive sleep apnea

    Article • EBioMedicine, March 2021, Elsevier

    Prof Claudia Cavadas

  13. Neuropeptide Y (NPY) intranasal delivery alleviates Machado–Joseph disease

    Article • Scientific Reports, February 2021, Springer Science + Business Media

    Prof Claudia Cavadas

  14. Common risk factors and therapeutic targets in obstructive sleep apnea and osteoarthritis: An unexpectable link?

    Article • Pharmacological Research, February 2021, Elsevier

    Prof Claudia Cavadas

  15. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

    Article • Autophagy, January 2021, Taylor & Francis

    MD, PhD Pierre-Louis Tharaux, Joilson O. Martins, Dr. rer. nat. Marc Herb, Dr Marcia R Cominetti, Alessio Di Fonzo, Christoph Gerhardt, Dr Mustafa Sahin, Dr Cinzia Volonté, Dr Marc Etienne Poirot, Professor Paula I. Moreira, Executive Director, The Hormel Institute Robert Clarke, Prof Robert Bryson-Richardson, Professor Hyun Kyu Song, Prof Claudia Cavadas, Professor Po Sing Leung, Paula Ludovico, Javeed Shah, Giovanni Di Guardo, Dr Takeshi Noda, Professor Tullio Florio, Professor Kevin Coombs, Ning Chen

  16. The Superpowers of Our Sleep

    Article • Frontiers for Young Minds, December 2020, Frontiers

    Prof Claudia Cavadas

  17. Blueberry Consumption Challenges Hepatic Mitochondrial Bioenergetics and Elicits Transcriptomics Reprogramming in Healthy Wistar Rats

    Article • Pharmaceutics, November 2020, MDPI AG

    Prof Claudia Cavadas

  18. Trehalose alleviates the phenotype of Machado–Joseph disease mouse models

    Article • Journal of Translational Medicine, April 2020, Springer Science + Business Media

    Prof Claudia Cavadas

  19. Neuropeptide Y Enhances Progerin Clearance and Ameliorates the Senescent Phenotype of Human Hutchinson-Gilford Progeria Syndrome Cells

    Article • The Journals of Gerontology Series A, February 2020, Oxford University Press (OUP)

    Prof Claudia Cavadas

  20. Long-Term Continuous Positive Airway Pressure Treatment Ameliorates Biological Clock Disruptions in Obstructive Sleep Apnea

    Article • SSRN Electronic Journal, January 2020, Elsevier

    Prof Claudia Cavadas

  21. Dichotomous Sirtuins: Implications for Drug Discovery in Neurodegenerative and Cardiometabolic Diseases

    Article • Trends in Pharmacological Sciences, December 2019, Elsevier

    Prof Claudia Cavadas

  22. The importance of determining circadian parameters in pharmacological studies

    Article • British Journal of Pharmacology, July 2019, Wiley

    Prof Claudia Cavadas

  23. In vitro susceptibility of Trypanosoma brucei brucei to selected essential oils and their major components

    Article • Experimental Parasitology, July 2018, Elsevier

    Prof Claudia Cavadas

  24. Dipeptidyl peptidase IV (DPP-IV) inhibition prevents fibrosis in adipose tissue of obese mice

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, March 2018, Elsevier

    Prof Claudia Cavadas

  25. Molecular Mechanisms and Cellular Pathways Implicated in Machado-Joseph Disease Pathogenesis

    Article • January 2018, Springer Science + Business Media

    Prof Claudia Cavadas

  26. Role of Beta-adrenergic Receptors and Sirtuin Signaling in the Heart During Aging, Heart Failure, and Adaptation to Stress

    Article • Cellular and Molecular Neurobiology, October 2017, Springer Science + Business Media

    Prof Claudia Cavadas

  27. Obstructive Sleep Apnea and Hallmarks of Aging

    Article • Trends in Molecular Medicine, August 2017, Elsevier

    Prof Claudia Cavadas

  28. The NAD+-dependent deacetylase SIRT2 attenuates oxidative stress and mitochondrial dysfunction and improves insulin sensitivity in hepatocytes

    Article • Human Molecular Genetics, July 2017, Oxford University Press (OUP)

    Prof Claudia Cavadas

  29. Quizzes as an active learning strategy: A study with students of pharmaceutical sciences

    Article • June 2017, Institute of Electrical & Electronics Engineers (IEEE)

    Prof Claudia Cavadas

  30. Unraveling the Role of Ataxin-2 in Metabolism

    Article • Trends in Endocrinology and Metabolism, April 2017, Elsevier

    Prof Claudia Cavadas

  31. Hypoxia mimetic induces lipid accumulation through mitochondrial dysfunction and stimulates autophagy in murine preadipocyte cell line

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, March 2017, Elsevier

    Prof Claudia Cavadas

  32. Hypothalamic Dysfunction in Obesity and Metabolic Disorders

    Article • January 2017, Springer Science + Business Media

    Prof Claudia Cavadas

  33. Neuropeptide Y (NPY) as a therapeutic target for neurodegenerative diseases

    Article • Neurobiology of Disease, November 2016, Elsevier

    Professor Claudia Cavadas, Prof Claudia Cavadas

  34. Caloric restriction stimulates autophagy in rat cortical neurons through neuropeptide Y and ghrelin receptors activation

    Article • Aging, August 2016, Impact Journals, LLC

    Professor Claudia Cavadas, Prof Claudia Cavadas

  35. The pathophysiology of defective proteostasis in the hypothalamus — from obesity to ageing

    Article • Nature Reviews Endocrinology, July 2016, Nature

    Professor Claudia Cavadas, Prof Claudia Cavadas

  36. Antileishmanial activity of antiretroviral drugs combined with miltefosine

    Article • Zeitschrift für Parasitenkunde Parasitology Research, June 2016, Springer Science + Business Media

    Professor Claudia Cavadas, Prof Claudia Cavadas

  37. Corrigendum to “Intracellular mechanisms coupled to NPY Y2 and Y5 receptor activation and lipid accumulation in murine adipocytes” [neuropeptides 46/6 (2012) 359–366]

    Article • Neuropeptides, June 2016, Elsevier

    Prof Claudia Cavadas

  38. Caloric restriction blocks neuropathology and motor deficits in Machado–Joseph disease mouse models through SIRT1 pathway

    Article • Nature Communications, May 2016, Nature

    Professor Claudia Cavadas, Prof Claudia Cavadas

  39. The Adenosinergic System in Diabetic Retinopathy

    Article • Journal of Diabetes Research, January 2016, Hindawi Publishing Corporation

    Prof Claudia Cavadas

  40. Neuropeptide Y: An Anti-Aging Player?

    Article • Trends in Neurosciences, November 2015, Elsevier

    Professor Claudia Cavadas, Prof Claudia Cavadas

  41. Emerging Role of Sirtuin 2 in the Regulation of Mammalian Metabolism

    Article • Trends in Pharmacological Sciences, November 2015, Elsevier

    Professor Claudia Cavadas, Prof Claudia Cavadas

  42. Impaired adrenal medullary function in a mouse model of depression induced by unpredictable chronic stress

    Article • European Neuropsychopharmacology, October 2015, Elsevier

    Professor Claudia Cavadas, Prof Claudia Cavadas

  43. Activation of Neuropeptide Y Receptors Modulates Retinal Ganglion Cell Physiology and Exerts Neuroprotective ActionsIn Vitro

    Article • ASN NEURO, August 2015, SAGE Publications

    Prof Claudia Cavadas

  44. Neuropeptide Y mitigates neuropathology and motor deficits in mouse models of Machado–Joseph disease

    Article • Human Molecular Genetics, July 2015, Oxford University Press (OUP)

    Professor Claudia Cavadas, Prof Claudia Cavadas

  45. Neuropeptide Y system in the retina: From localization to function

    Article • Progress in Retinal and Eye Research, July 2015, Elsevier

    Professor Claudia Cavadas, Prof Claudia Cavadas

  46. NPY/neuropeptide Y enhances autophagy in the hypothalamus: a mechanism to delay aging?

    Article • Autophagy, June 2015, Taylor & Francis

    Professor Claudia Cavadas, Prof Claudia Cavadas

  47. Neuropeptide Y stimulates autophagy in hypothalamic neurons

    Article • Proceedings of the National Academy of Sciences, March 2015, Proceedings of the National Academy of Sciences

    Professor Claudia Cavadas, Prof Claudia Cavadas

  48. Hypothalamic involvement in premature aging laminopathies

    Article • Orphanet Journal of Rare Diseases, January 2015, Springer Science + Business Media

    Professor Claudia Cavadas, Prof Claudia Cavadas

  49. Alterations in phospholipidomic profile in the brain of mouse model of depression induced by chronic unpredictable stress

    Article • Neuroscience, July 2014, Elsevier

    Prof Claudia Cavadas

  50. Fluoxetine Induces Proliferation and Inhibits Differentiation of Hypothalamic Neuroprogenitor Cells In Vitro

    Article • PLoS ONE, March 2014, PLOS

    Professor Claudia Cavadas, Prof Claudia Cavadas

  51. Role of hypothalamic neurogenesis in feeding regulation

    Article • Trends in Endocrinology and Metabolism, February 2014, Elsevier

    Professor Claudia Cavadas, Prof Claudia Cavadas

  52. MicroRNAs in Obesity and Metabolism

    Article • January 2014, Springer Science + Business Media

    Professor Claudia Cavadas, Prof Claudia Cavadas

  53. Catecholamine Release Modulation by Adenosine through A2AReceptors in Mouse Chromaffin Cell Culture

    Article • January 2014, Elsevier

    Professor Claudia Cavadas, Prof Claudia Cavadas

  54. Chronic Unpredictable Stress Induces Catecholaminergic System Changes in Mouse Adrenal Gland

    Article • January 2014, Elsevier

    Professor Claudia Cavadas, Prof Claudia Cavadas

  55. Emerging novel roles of neuropeptide Y in the retina: From neuromodulation to neuroprotection

    Article • Progress in Neurobiology, January 2014, Elsevier

    Professor Claudia Cavadas, Prof Claudia Cavadas

  56. Progenitor Cells in Chromospheres: In Response to Arthur S. Tischler

    Article • Stem Cells Translational Medicine, October 2013, Wiley

    Prof Claudia Cavadas

  57. Effect of Diabetes/Hyperglycemia on the Rat Retinal Adenosinergic System

    Article • PLoS ONE, June 2013, PLOS

    Professor Claudia Cavadas, Prof Claudia Cavadas

  58. Neuropeptide Y receptors activation protects rat retinal neural cells against necrotic and apoptotic cell death induced by glutamate

    Article • Cell Death and Disease, May 2013, Springer Science + Business Media

    Prof Claudia Cavadas

  59. Neuropeptide Y Receptors Y 1 and Y 2 are Present in Neurons and Glial Cells in Rat Retinal Cells in Culture

    Article • Investigative Ophthalmology & Visual Science, January 2013, Association for Research in Vision and Ophthalmology (ARVO)

    Professor Claudia Cavadas, Prof Claudia Cavadas

  60. Intracellular mechanisms coupled to NPY Y2 and Y5 receptor activation and lipid accumulation in murine adipocytes

    Article • Neuropeptides, December 2012, Elsevier

    Prof Claudia Cavadas

  61. Isolation, Characterization, and Differentiation of Progenitor Cells from Human Adult Adrenal Medulla

    Article • Stem Cells Translational Medicine, October 2012, Wiley

    Prof Claudia Cavadas

  62. Dipeptidyl-peptidase-IV by cleaving neuropeptide Y induces lipid accumulation and PPAR-γ expression

    Article • Peptides, September 2012, Elsevier

    Professor Claudia Cavadas, Prof Claudia Cavadas

  63. Contribution of TNF receptor 1 to retinal neural cell death induced by elevated glucose

    Article • Molecular and Cellular Neuroscience, May 2012, Elsevier

    Prof Claudia Cavadas

  64. Regulation of catecholamine release in human adrenal chromaffin cells by β-adrenoceptors

    Article • Neurochemistry International, March 2012, Elsevier

    Professor Claudia Cavadas, Prof Claudia Cavadas

  65. Effects of 3,4-Methylenedioxymethamphetamine Administration on Retinal Physiology in the Rat

    Article • PLoS ONE, December 2011, PLOS

    Professor Claudia Cavadas, Prof Claudia Cavadas

  66. Moderate Long-Term Modulation of Neuropeptide Y in Hypothalamic Arcuate Nucleus Induces Energy Balance Alterations in Adult Rats

    Article • PLoS ONE, July 2011, PLOS

    Professor Claudia Cavadas, Prof Claudia Cavadas

  67. Proliferative Hypothalamic Neurospheres Express NPY, AGRP, POMC, CART and Orexin-A and Differentiate to Functional Neurons

    Article • PLoS ONE, May 2011, PLOS

    Professor Claudia Cavadas, Prof Claudia Cavadas

  68. Neuropeptide Y inhibits [Ca2+]ichanges in rat retinal neurons through NPY Y1, Y4, and Y5receptors

    Article • Journal of Neurochemistry, June 2009, Wiley

    Professor Claudia Cavadas, Prof Claudia Cavadas

  69. Regulation of catecholamine release and tyrosine hydroxylase in human adrenal chromaffin cells by interleukin-1β: role of neuropeptide Y and nitric oxide

    Article • Journal of Neurochemistry, May 2009, Wiley

    Professor Claudia Cavadas, Prof Claudia Cavadas

  70. Neuropeptide Y Family Peptides

    Article • April 2009, Taylor & Francis

    Professor Claudia Cavadas, Prof Claudia Cavadas

  71. Stress-Induced Hypertension and Increased Sympathetic Activity in Mice Overexpressing Neuropeptide Y in Noradrenergic Neurons

    Article • Neuroendocrinology, January 2009, Karger Publishers

    Professor Claudia Cavadas, Prof Claudia Cavadas

  72. Interaction between neuropeptide Y (NPY) and brain-derived neurotrophic factor in NPY-mediated neuroprotection against excitotoxicity: a role for microglia

    Article • European Journal of Neuroscience, April 2008, Wiley

    Prof Claudia Cavadas

  73. Neuropeptide Y stimulates retinal neural cell proliferation - involvement of nitric oxide

    Article • Journal of Neurochemistry, March 2008, Wiley

    Professor Claudia Cavadas, Prof Claudia Cavadas

  74. Neuropeptide Y protects retinal neural cells against cell death induced by ecstasy

    Article • Neuroscience, March 2008, Elsevier

    Prof Claudia Cavadas

  75. Intracellular signaling mechanisms mediating catecholamine release upon activation of NPY Y1receptors in mouse chromaffin cells

    Article • Journal of Neurochemistry, November 2007, Wiley

    Professor Claudia Cavadas, Prof Claudia Cavadas

  76. NPY in rat retina is present in neurons, in endothelial cells and also in microglial and Müller cells

    Article • Neurochemistry International, April 2007, Elsevier

    Professor Claudia Cavadas, Prof Claudia Cavadas

  77. NPY Y1 receptor is not involved in the hemodynamic response to an acute cold pressor test in mice

    Article • Peptides, February 2007, Elsevier

    Professor Thierry Pedrazzini, Professor Claudia Cavadas, Prof Claudia Cavadas

  78. Neuropeptide Y regulates catecholamine release evoked by interleukin-1β in mouse chromaffin cells

    Article • Peptides, February 2007, Elsevier

    Professor Claudia Cavadas, Prof Claudia Cavadas

  79. Deletion of the neuropeptide Y (NPY) Y 1 receptor gene reveals a regulatory role of NPY on catecholamine synthesis and secretion

    Article • Proceedings of the National Academy of Sciences, July 2006, Proceedings of the National Academy of Sciences

    Prof Claudia Cavadas

  80. The Putative Neuroprotective Role of Neuropeptide Y in the Central Nervous System

    Article • Current Drug Targets - CNS & Neurological Disorders, August 2005, Bentham Science Publishers

    Prof Claudia Cavadas

  81. Neuropeptide Y expression, localization and cellular transducing effects in HUVEC

    Article • Biology of the Cell, June 2005, Wiley

    Professor Claudia Cavadas, Prof Claudia Cavadas

  82. Up-regulation of neuropeptide Y levels and modulation of glutamate release through neuropeptide Y receptors in the hippocampus of kainate-induced epileptic rats

    Article • Journal of Neurochemistry, April 2005, Wiley

    Professor Claudia Cavadas, Prof Claudia Cavadas

  83. NPY, NPY receptors, and DPP IV activity are modulated by LPS, TNF-α and IFN-γ in HUVEC

    Article • Regulatory Peptides, November 2003, Elsevier

    Professor Claudia Cavadas, Prof Claudia Cavadas

  84. Blood sampling methodology is crucial for precise measurement of plasma catecholamines concentrations in mice

    Article • Pflügers Archiv - European Journal of Physiology, November 2003, Springer Science + Business Media

    Professor Claudia Cavadas, Prof Claudia Cavadas

  85. Angiotensin II mediates catecholamine and neuropeptide Y secretion in human adrenal chromaffin cells through the AT1 receptor

    Article • Regulatory Peptides, March 2003, Elsevier

    Professor Claudia Cavadas, Prof Claudia Cavadas

  86. Neuropeptide Y and its receptors as potential therapeutic drug targets

    Article • Clinica Chimica Acta, December 2002, Elsevier

    Professor Claudia Cavadas, Prof Claudia Cavadas

  87. Catecholamine and Neuropeptide Y Secretion from Human Adrenal Chromaffin Cells

    Article • Annals of the New York Academy of Sciences, October 2002, Wiley

    Professor Claudia Cavadas, Prof Claudia Cavadas

  88. Differential Secretion of Catecholamine and Neuropeptide Y in Response to KCl from Mice Chromaffin Cells

    Article • Annals of the New York Academy of Sciences, October 2002, Wiley

    Professor Claudia Cavadas, Prof Claudia Cavadas

  89. Dibasic cleavage site is required for sorting to the regulated secretory pathway for both pro- and neuropeptide Y

    Article • Journal of Neurochemistry, June 2002, Wiley

    Professor Claudia Cavadas, Prof Claudia Cavadas

  90. Interplay Between Galanin and Leptin in the Hypothalamic Control of Feeding via Corticotropin-Releasing Hormone and Neuropeptide Y

    Article • Diabetes, December 2001, American Diabetes Association

    Prof Claudia Cavadas

  91. Cardiovascular effects of fentanyl in conscious rats

    Article • Pflügers Archiv - European Journal of Physiology, August 2001, Springer Science + Business Media

    Professor Claudia Cavadas, Prof Claudia Cavadas

  92. In vitro study of the interaction of Tilia europeae L. aqueous extract with GABAA receptors in rat brain

    Article • Phytotherapy Research, February 1997, Wiley

    Prof Claudia Cavadas