All Stories

  1. Regulation of Metabolic Rhythms by Glial Clocks
  2. Neuroendocrine timekeepers: changes in normal and premature aging
  3. Circadian rhythms are disrupted in patients and preclinical models of Machado-Joseph disease
  4. The Therapeutic Potential of Melatonin and Its Novel Synthetic Analogs in Circadian Rhythm Sleep Disorders, Inflammation‐Associated Pathologies, and Neurodegenerative Diseases
  5. The (un)known crosstalk between metabolism and mechanotransduction: Implications for metabolic syndrome (MetS)-associated neurological complications
  6. Restoring neuropetide Y levels in the hypothalamus ameliorates premature aging phenotype in mice
  7. Senescent cell transplantation into the skin induces age‐related peripheral dysfunction and cognitive decline
  8. Modeling hypothalamic pathophysiology in vitro for metabolic, circadian, and sleep disorders
  9. Lipodystrophy as a target to delay premature aging
  10. Ghrelin delays premature aging in Hutchinson‐Gilford progeria syndrome
  11. Primary cilia shape hallmarks of health and aging
  12. Cellular Senescence: From Mechanisms to Current Biomarkers and Senotherapies
  13. Ataxin-2 in the hypothalamus at the crossroads between metabolism and clock genes
  14. The impact of insomnia on frailty and the hallmarks of aging
  15. Obstructive sleep apnea impact on physiology: insights from a mouse model and a case-control study
  16. The impact of obstructive sleep apnea treatment with continuous positive airway pressure on the biological clock
  17. SIRT1 activation and its circadian clock control: a promising approach against (frailty in) neurodegenerative disorders
  18. Peripheral biomarkers to diagnose obstructive sleep apnea in adults: A systematic review and meta-analysis
  19. SIRT2 Deficiency Exacerbates Hepatic Steatosis via a Putative Role of the ER Stress Pathway
  20. PET Imaging of the Neuropeptide Y System: A Systematic Review
  21. A look on food intake and satiety: from humans to rodent models
  22. Skin senescence: mechanisms and impact on whole-body aging
  23. Blueberry Counteracts Prediabetes in a Hypercaloric Diet-Induced Rat Model and Rescues Hepatic Mitochondrial Bioenergetics
  24. Small-molecule modulators of the circadian clock: Pharmacological potentials in circadian-related diseases
  25. The NutriClock Study Protocol - Assessing the Impact of a Chrononutrition Intervention in Patients With Cardiometabolic Disturbances
  26. PI3K/AKT/MTOR and ERK1/2-MAPK signaling pathways are involved in autophagy stimulation induced by caloric restriction or caloric restriction mimetics in cortical neurons
  27. Long-term continuous positive airway pressure treatment ameliorates biological clock disruptions in obstructive sleep apnea
  28. Neuropeptide Y (NPY) intranasal delivery alleviates Machado–Joseph disease
  29. Common risk factors and therapeutic targets in obstructive sleep apnea and osteoarthritis: An unexpectable link?
  30. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
  31. The Superpowers of Our Sleep
  32. Blueberry Consumption Challenges Hepatic Mitochondrial Bioenergetics and Elicits Transcriptomics Reprogramming in Healthy Wistar Rats
  33. Trehalose alleviates the phenotype of Machado–Joseph disease mouse models
  34. Neuropeptide Y Enhances Progerin Clearance and Ameliorates the Senescent Phenotype of Human Hutchinson-Gilford Progeria Syndrome Cells
  35. Long-Term Continuous Positive Airway Pressure Treatment Ameliorates Biological Clock Disruptions in Obstructive Sleep Apnea
  36. Dichotomous Sirtuins: Implications for Drug Discovery in Neurodegenerative and Cardiometabolic Diseases
  37. The importance of determining circadian parameters in pharmacological studies
  38. In vitro susceptibility of Trypanosoma brucei brucei to selected essential oils and their major components
  39. Dipeptidyl peptidase IV (DPP-IV) inhibition prevents fibrosis in adipose tissue of obese mice
  40. Molecular Mechanisms and Cellular Pathways Implicated in Machado-Joseph Disease Pathogenesis
  41. Role of Beta-adrenergic Receptors and Sirtuin Signaling in the Heart During Aging, Heart Failure, and Adaptation to Stress
  42. Obstructive Sleep Apnea and Hallmarks of Aging
  43. The NAD+-dependent deacetylase SIRT2 attenuates oxidative stress and mitochondrial dysfunction and improves insulin sensitivity in hepatocytes
  44. Quizzes as an active learning strategy: A study with students of pharmaceutical sciences
  45. Unraveling the Role of Ataxin-2 in Metabolism
  46. Hypoxia mimetic induces lipid accumulation through mitochondrial dysfunction and stimulates autophagy in murine preadipocyte cell line
  47. Hypothalamic Dysfunction in Obesity and Metabolic Disorders
  48. Neuropeptide Y (NPY) as a therapeutic target for neurodegenerative diseases
  49. Caloric restriction stimulates autophagy in rat cortical neurons through neuropeptide Y and ghrelin receptors activation
  50. The pathophysiology of defective proteostasis in the hypothalamus — from obesity to ageing
  51. Antileishmanial activity of antiretroviral drugs combined with miltefosine
  52. Corrigendum to “Intracellular mechanisms coupled to NPY Y2 and Y5 receptor activation and lipid accumulation in murine adipocytes” [neuropeptides 46/6 (2012) 359–366]
  53. Caloric restriction blocks neuropathology and motor deficits in Machado–Joseph disease mouse models through SIRT1 pathway
  54. The Adenosinergic System in Diabetic Retinopathy
  55. Neuropeptide Y: An Anti-Aging Player?
  56. Emerging Role of Sirtuin 2 in the Regulation of Mammalian Metabolism
  57. Impaired adrenal medullary function in a mouse model of depression induced by unpredictable chronic stress
  58. Activation of Neuropeptide Y Receptors Modulates Retinal Ganglion Cell Physiology and Exerts Neuroprotective ActionsIn Vitro
  59. Neuropeptide Y mitigates neuropathology and motor deficits in mouse models of Machado–Joseph disease
  60. Neuropeptide Y system in the retina: From localization to function
  61. NPY/neuropeptide Y enhances autophagy in the hypothalamus: a mechanism to delay aging?
  62. Neuropeptide Y stimulates autophagy in hypothalamic neurons
  63. Hypothalamic involvement in premature aging laminopathies
  64. Alterations in phospholipidomic profile in the brain of mouse model of depression induced by chronic unpredictable stress
  65. Fluoxetine Induces Proliferation and Inhibits Differentiation of Hypothalamic Neuroprogenitor Cells In Vitro
  66. Role of hypothalamic neurogenesis in feeding regulation
  67. MicroRNAs in Obesity and Metabolism
  68. Catecholamine Release Modulation by Adenosine Through A2a Receptors in Mouse Chromaffin Cells in Culture
  69. Catecholamine Release Modulation by Adenosine through A2AReceptors in Mouse Chromaffin Cell Culture
  70. Chronic Unpredictable Stress Induces Catecholaminergic System Changes in Mouse Adrenal Gland
  71. Emerging novel roles of neuropeptide Y in the retina: From neuromodulation to neuroprotection
  72. Progenitor Cells in Chromospheres: In Response to Arthur S. Tischler
  73. Effect of Diabetes/Hyperglycemia on the Rat Retinal Adenosinergic System
  74. Neuropeptide Y receptors activation protects rat retinal neural cells against necrotic and apoptotic cell death induced by glutamate
  75. Neuropeptide Y Receptors Y 1 and Y 2 are Present in Neurons and Glial Cells in Rat Retinal Cells in Culture
  76. Intracellular mechanisms coupled to NPY Y2 and Y5 receptor activation and lipid accumulation in murine adipocytes
  77. Isolation, Characterization, and Differentiation of Progenitor Cells from Human Adult Adrenal Medulla
  78. Dipeptidyl-peptidase-IV by cleaving neuropeptide Y induces lipid accumulation and PPAR-γ expression
  79. Contribution of TNF receptor 1 to retinal neural cell death induced by elevated glucose
  80. Regulation of catecholamine release in human adrenal chromaffin cells by β-adrenoceptors
  81. Effects of 3,4-Methylenedioxymethamphetamine Administration on Retinal Physiology in the Rat
  82. Moderate Long-Term Modulation of Neuropeptide Y in Hypothalamic Arcuate Nucleus Induces Energy Balance Alterations in Adult Rats
  83. Proliferative Hypothalamic Neurospheres Express NPY, AGRP, POMC, CART and Orexin-A and Differentiate to Functional Neurons
  84. Neuropeptide Y inhibits [Ca2+]ichanges in rat retinal neurons through NPY Y1, Y4, and Y5receptors
  85. Regulation of catecholamine release and tyrosine hydroxylase in human adrenal chromaffin cells by interleukin-1β: role of neuropeptide Y and nitric oxide
  86. Neuropeptide Y Family Peptides
  87. Stress-Induced Hypertension and Increased Sympathetic Activity in Mice Overexpressing Neuropeptide Y in Noradrenergic Neurons
  88. Interaction between neuropeptide Y (NPY) and brain-derived neurotrophic factor in NPY-mediated neuroprotection against excitotoxicity: a role for microglia
  89. Neuropeptide Y stimulates retinal neural cell proliferation - involvement of nitric oxide
  90. Neuropeptide Y protects retinal neural cells against cell death induced by ecstasy
  91. Intracellular signaling mechanisms mediating catecholamine release upon activation of NPY Y1receptors in mouse chromaffin cells
  92. NPY in rat retina is present in neurons, in endothelial cells and also in microglial and Müller cells
  93. NPY Y1 receptor is not involved in the hemodynamic response to an acute cold pressor test in mice
  94. Neuropeptide Y regulates catecholamine release evoked by interleukin-1β in mouse chromaffin cells
  95. Deletion of the neuropeptide Y (NPY) Y 1 receptor gene reveals a regulatory role of NPY on catecholamine synthesis and secretion
  96. The Putative Neuroprotective Role of Neuropeptide Y in the Central Nervous System
  97. Neuropeptide Y expression, localization and cellular transducing effects in HUVEC
  98. Up-regulation of neuropeptide Y levels and modulation of glutamate release through neuropeptide Y receptors in the hippocampus of kainate-induced epileptic rats
  99. NPY, NPY receptors, and DPP IV activity are modulated by LPS, TNF-α and IFN-γ in HUVEC
  100. Blood sampling methodology is crucial for precise measurement of plasma catecholamines concentrations in mice
  101. Angiotensin II mediates catecholamine and neuropeptide Y secretion in human adrenal chromaffin cells through the AT1 receptor
  102. Neuropeptide Y and its receptors as potential therapeutic drug targets
  103. Catecholamine and Neuropeptide Y Secretion from Human Adrenal Chromaffin Cells
  104. Differential Secretion of Catecholamine and Neuropeptide Y in Response to KCl from Mice Chromaffin Cells
  105. Dibasic cleavage site is required for sorting to the regulated secretory pathway for both pro- and neuropeptide Y
  106. Interplay Between Galanin and Leptin in the Hypothalamic Control of Feeding via Corticotropin-Releasing Hormone and Neuropeptide Y
  107. NPY Regulates Catecholamine Secretion from Human Adrenal Chromaffin Cells
  108. Cardiovascular effects of fentanyl in conscious rats
  109. In vitro study of the interaction of Tilia europeae L. aqueous extract with GABAA receptors in rat brain