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Diabetes is the main cause of renal insufficiency in industrialized countries. Here we identified a molecular mechanism by which renal cells are altered in diabetic patients and showed a therapeutic option to prevent renal injury in diabetes.
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This page is a summary of: Podocyte Injury in Diabetic Kidney Disease in Mouse Models Involves TRPC6-mediated Calpain Activation Impairing Autophagy, Journal of the American Society of Nephrology, September 2023, Wolters Kluwer Health,
DOI: 10.1681/asn.0000000000000212.
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