Publication
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function
John Chalmers, James Scott, Reiner Biffar, Jorma Viikari, Angelo Scuteri, Reinhold Schmidt, Josef Coresh, Joban S. Sehmi, Rita P. S. Middelberg, Joshua C. Denny, Mark Seielstad, Robert J. Carroll, Juha Karjalainen, Sudha Seshadri, Brenda W. Penninx, Jyotika K. Fernandes, Pankaj Sharma, Rodney J. Scott, Karlhans Endlich, Sue Shaw-Hawkins, Ronit Katz, Katja Butterbach, Gang Shi, Sanaz Sedaghat, Keith L. Keene, Nick R. G. Shrine, Sarah H. Wild, Kurt Lohman, Eric J. G. Sijbrands, Sharon L. R. Kardia, Laura Portas, Xueling Sim, Sheila Ulivi, Lenore J. Launer, Andrew Singleton, Shih-Jen Hwang, Leo-Pekka Lyytikäinen, Marketa Sjögren, Stefan Enroth, Loic Yengo, Nicholas L. Smith, Stefan Kloiber, Lude Franke, Maria Soler Artigas, Stella Trompet, Luigi Ferrucci, Tim D. Spector, Benedicte Stengel, Lynda M. Rose, Jan A. Staessen, Stephen J. Hancock, Lyudmyla Kedenko, Alena Stancakova, Stephen T. Turner, Madhumathi Rao, Nanette I. Steinle, Sylvia E. Rosas, Maksim Struchalin, David P. Strachan, Sylvia Stracke, Marcus E. Kleber, Heather M. Stringham, Tamara B. Harris, Margherita Cavalieri, Yan V. Sun, Tanja Zeller, Margot Haun, Amy J. Swift, Tatijana Zemunik, Marilyn C. Cornelis, Yasuharu Tabara, Terho Lehtimäki, Marina Ciullo, E-Shyong Tai, Thomas Illig, Mario Pirastu, Philippa J. Talmud, Thor Aspelund, Mariza de Andrade, Andrew Taylor, Tiit Nikopensius, Mark A. McEvoy, Janos Terzic, Tonu Esko, Mark Woodward, Dag S. Thelle, Toshiko Tanaka, Martin Adam, Martin D. Tobin, Ulf Gyllensten, Massimiliano Cocca, Maciej Tomaszewski, Uwe Völker, Matthias Nauck, Vikal Tripathy, Valur Emilsson, Medea Imboden, Jaakko Tuomilehto, Veronique Vitart, Melanie Waldenberger, Ioanna Tzoulaki, Ville Aalto, Menno Pruijm, Manuela Uda, Vilmundur Gudnason, Marie Metzger, Hirotsugu Ueshima, Vincent Chouraki, Michael Stumvoll, Cuno S. P. M. Uiterwaal, Wei-Min Chen, Michele K. Evans, Satoshi Umemura, Wilmar Igl, Michele M. Sale, Pim van der Harst, Winfried März, Mika Kähönen, Yvonne T. van der Schouw, Wolfgang Koenig, Mladen Boban, Wiek H. van Gilst, Wolfgang Lieb, Murielle Bochud, Erkki Vartiainen, Ruth J. F. Loos, Myriam Rheinberger, Ramachandran S. Vasan, Yongmei Liu, Niek Verweij, Gudrun Veldre, Harold Snieder, Nabila Bouatia-Naji, Germaine C. Verwoert, Peter P. Pramstaller, Nicholas G. Martin, Margus Viigimaa, Afshin Parsa, Nick Hastie, D. G. Vinay, Jeffrey R. O’Connell, Nicole Probst-Hensch, Paolo Vineis, Katalin Susztak, Nicole Soranzo, Benjamin F. Voight, Pavel Hamet, Olivier Devuyst, Peter Vollenweider, Johanne Tremblay, Olli Raitakari, Lynne E. Wagenknecht, Ian H. de Boer, Omri Gottesman, Louise V. Wain, Carsten A. Böger, Oscar H. Franco, Xiaoling Wang, Wolfram Goessling, Ozren Polasek, Thomas J. Wang, Daniel I. Chasman, Paolo Gasparini, Nicholas J. Wareham, Anna Köttgen, Patricia B. Munroe, Hugh Watkins, W. H. Linda Kao, Paul M. Ridker, Alan B. Weder, Caroline S. Fox, Paul Mitchell, Peter H. Whincup, Paul Muntner, Kerri L. Wiggins, Christa Meisinger, Jacqueline C. M. Witteman, Johannes H. Smit, Andrew Wong, Goncalo R. Abecasis, Ying Wu, Linda S. Adair, Chittaranjan S. Yajnik, Myriam Alexander, Jie Yao, David Altshuler, J. H. Young, Najaf Amin, Diana Zelenika, Dan E. Arking, Guangju Zhai, Pankaj Arora, Weihua Zhang, Yurii Aulchenko, Feng Zhang, Stephan J. L. Bakker, Jing Hua Zhao, Stefania Bandinelli, Haidong Zhu, Ines Barroso, Xiaofeng Zhu, Jacques S. Beckmann, Paavo Zitting, John P. Beilby, Ewa Zukowska-Szczechowska, Richard N. Bergman, Yukinori Okada, Sven Bergmann, Jer-Yuarn Wu, Joshua C. Bis, Dongfeng Gu, Michael Boehnke, Fumihiko Takeuchi, Lori L. Bonnycastle, Atsushi Takahashi, Stefan R. Bornstein, Shiro Maeda, Michiel L. Bots, Tatsuhiko Tsunoda, Jennifer L. Bragg-Gresham, Peng Chen, Stefan-Martin Brand, Su-Chi Lim, Eva Brand, Tien-Yin Wong, Peter S. Braund, Jianjun Liu, Morris J. Brown, Terri L. Young, Paul R. Burton, Tin Aung, Juan P. Casas, Yik-Ying Teo, Mark J. Caulfield, Young Jin Kim, Aravinda Chakravarti, Daehee Kang, John C. Chambers, Chien-Hsiun Chen, Giriraj R. Chandak, Fuu-Jen Tsai, Yen-Pei C. Chang, Li-Ching Chang, Fadi J. Charchar, S. -J. Cathy Fann, Nish Chaturvedi, Hao Mei, Yoon Shin Cho, James E. Hixson, Robert Clarke, Shufeng Chen, Francis S. Collins, Tomohiro Katsuya, Rory Collins, Masato Isono, John M. Connell, Eva Albrecht, Jackie A. Cooper, Kazuhiko Yamamoto, Matthew N. Cooper, Michiaki Kubo, Richard S. Cooper, Yusuke Nakamura, Anna Maria Corsi, Naoyuki Kamatani, Marcus Dörr, Norihiro Kato, Santosh Dahgam, Jiang He, John Danesh, Yuan-Tsong Chen, George Davey Smith, Toshihiro Tanaka, Ian N. M. Day, Muredach P Reilly, Panos Deloukas, Heribert Schunkert, Matthew Denniff, Themistocles L. Assimes, Anna F. Dominiczak, Alistair Hall, Yanbin Dong, Christian Hengstenberg, Ayo Doumatey, Inke R. König, Paul Elliott, Reijo Laaksonen, Roberto Elosua, Ruth McPherson, Jeanette Erdmann, John R. Thompson, Susana Eyheramendy, Unnur Thorsteinsdottir, Martin Farrall, Andreas Ziegler, Cristiano Fava, Devin Absher, Terrence Forrester, Li Chen, F. Gerald R. Fowkes, L. Adrienne Cupples, Ervin R. Fox, Eran Halperin, Timothy M. Frayling, Mingyao Li, Pilar Galan, Kiran Musunuru, Santhi K. Ganesh, Michael Preuss, Melissa Garcia, Arne Schillert, Cristian Pattaro, Tom R. Gaunt, Gudmar Thorleifsson, Alexander Teumer, Nicole L. Glazer, George A. Wells, Mathias Gorski, Min Jin Go, Hilma Holm, Audrey Y. Chu, Anuj Goel, Robert Roberts, Man Li, Jürgen Grässler, Alexandre F. R. Stewart, Vladan Mijatovic, Diederick E. Grobbee, Stephen Fortmann, Maija Garnaas, Leif Groop, Alan Go, Adrienne Tin, Simonetta Guarrera, Mark Hlatky, Rossella Sorice, Xiuqing Guo, Carlos Iribarren, Yong Li, David Hadley, Joshua Knowles, Daniel Taliun, Anders Hamsten, Richard Myers, Matthias Olden, Bok-Ghee Han, Thomas Quertermous, Meredith Foster, Rebecca Hardy, Steven Sidney, Qiong Yang, Anna-Liisa Hartikainen, Neil Risch, Ming-Huei Chen, Simon Heath, Hua Tang, Tune H. Pers, Susan R. Heckbert, Stefan Blankenberg, Andrew D. Johnson, Bo Hedblad, Renate Schnabel, Yi-An Ko, Serge Hercberg, Christoph Sinning, Christian Fuchsberger, Dena Hernandez, Karl J. Lackner, Bamidele Tayo, Andrew A. Hicks, Laurence Tiret, Michael Nalls, Gina Hilton, Viviane Nicaud, Mary F. Feitosa, Aroon D. Hingorani, Francois Cambien, Aaron Isaacs, Judith A Hoffman Bolton, Christoph Bickel, Abbas Dehghan, Jemma C. Hopewell, Hans J. Rupprecht, Pio d’Adamo, Philip Howard, Claire Perret, Adebowale Adeyemo, Steve E. Humphries, Carole Proust, Aida Karina Dieffenbach, Steven C. Hunt, Thomas F. Münzel, Alan B. Zonderman, Kristian Hveem, Maja Barbalic, Ilja M. Nolte, M. Arfan Ikram, Ida Yii-Der Chen, Peter J. van der Most, Muhammad Islam, Serkalem Demissie-Banjaw, Alan F. Wright, Naoharu Iwai, Aaron Folsom, Alan R. Shuldiner, Marjo-Riitta Jarvelin, Thomas Lumley, Alanna C. Morrison, Anne U. Jackson, Kristin Marciante, Albert Hofman, Tazeen H. Jafar, Kent D. Taylor, Albert V. Smith, Charles S. Janipalli, Kelly Volcik, Albert W. Dreisbach, Toby Johnson, Solveig Gretarsdottir, Andre Franke, Sekar Kathiresan, Jeffrey R. Gulcher, Andre G. Uitterlinden, Kay-Tee Khaw, Augustine Kong, Andres Metspalu, Hyung-Lae Kim, Kari Stefansson, Anke Tonjes, Sanjay Kinra, Gudmundur Thorgeirsson, Antonio Lupo, Yoshikuni Kita, Karl Andersen, Antonietta Robino, Mika Kivimaki, Marcus Fischer, Åsa Johansson, Jaspal S. Kooner, Anika Grosshennig, Ayse Demirkan, M. J. Kranthi Kumar, Patrick Linsel-Nitschke, Barbara Kollerits, Diana Kuh, Klaus Stark, Barry I. Freedman, Smita R. Kulkarni, Stefan Schreiber, Belen Ponte, Meena Kumari, Zouhair Aherrahrou, Ben A. Oostra, Johanna Kuusisto, Petra Bruse, Bernhard Paulweber, Tatiana Kuznetsova, Angela Doering, Bernhard K. Krämer, Markku Laakso, Norman Klopp, Braxton D. Mitchell, Maris Laan, Patrick Diemert, Brendan M. Buckley, Jaana Laitinen, Christina Loley, Carmen A. Peralta, Edward G. Lakatta, Anja Medack, Caroline Hayward, Carl D. Langefeld, Janja Nahrstedt, Catherine Helmer, Martin G. Larson, Annette Peters, Charles N. Rotimi, Mark Lathrop, Arnika K. Wagner, Christian M. Shaffer, Debbie A. Lawlor, Christina Willenborg, Christian Müller, Robert W. Lawrence, Bernhard O. Böhm, Cinzia Sala, Jong-Young Lee, Harald Dobnig, Cornelia M. van Duijn, Nanette R. Lee, Tanja B. Grammer, Aude Saint-Pierre, Daniel Levy, Michael M. Hoffmann, Daniel Ackermann, Yali Li, Andreas Meinitzer, Daniel Shriner, Will T. Longstreth, Bernhard R. Winkelmann, Daniela Ruggiero, Jian’an Luan, Stefan Pilz, Daniela Toniolo, Gavin Lucas, Wilfried Renner, Yingchang Lu, Barbara Ludwig, Hubert Scharnagl, Daniele Cusi, Massimo Mangino, Tatjana Stojakovic, Darina Czamara, K. Radha Mani, Andreas Tomaschitz, David Ellinghaus, Michael G. Marmot, Karl Winkler, David S. Siscovick, Francesco U. S. Mattace-Raso, Candace Guiducci, Douglas Ruderfer, Giuseppe Matullo, Noel Burtt, Christian Gieger, Wendy L. McArdle, Stacey B. Gabriel, Harald Grallert, Colin A. McKenzie, Sonny Dandona, Elena Rochtchina, Thomas Meitinger, Olga Jarinova, Elizabeth J. Atkinson, Olle Melander, Liming Qu, Elizabeth G. Holliday, Pierre Meneton, Robert Wilensky, Eric Boerwinkle, James F. Meschia, William Matthai, Erika Salvi, Tetsuro Miki, Hakon H. Hakonarson, Erwin P. Bottinger, Yuri Milaneschi, Joe Devaney, Federico Murgia, Karen L. Mohlke, Mary Susan Burnett, Fernando Rivadeneira, Vincent Mooser, Augusto D. Pichard, Florian Ernst, Mario A. Morken, Kenneth M. Kent, Florian Kronenberg, Richard W. Morris, Lowell Satler, Frank B. Hu, Thomas H. Mosley, Joseph M. Lindsay, Gerjan J. Navis, Samer Najjar, Ron Waksman, Gary C. Curhan, Narisu Narisu, Christopher W. Knouff, George B. Ehret, Christopher Newton-Cheh, Dawn M. Waterworth, Georg Homuth, Khanh-Dung Hoang Nguyen, Max C. Walker, Stefan Coassin, Peter Nilsson, Stephen E. Epstein, Gian-Andri Thun, Fredrik Nyberg, Daniel J. Rader, Giorgio Pistis, Christopher J. O’Donnell, Christopher P. Nelson, Giovanni Gambaro, Toshio Ogihara, Benjamin J. Wright, Giovanni Malerba, Takayoshi Ohkubo, Anthony J. Balmforth, Grant W. Montgomery, Tomonori Okamura, Stephen G. Ball, Gudny Eiriksdottir, RickTwee-Hee Ong, Laura R. Loehr, Gunnar Jacobs, Halit Ongen, Wayne D. Rosamond, Guo Li, N. Charlotte Onland-Moret, Emelia Benjamin, H-Erich Wichmann, Paul F. O’Reilly, Talin Haritunians, Harry Campbell, Elin Org, David Couper, Helena Schmidt, Marco Orru, Joanne Murabito, Henri Wallaschofski, Walter Palmas, Ying A. Wang, Henry Völzke, Jutta Palmen, Bruno H. Stricker, Hermann Brenner, Lyle J. Palmer, Patricia P. Chang, Heyo K. Kroemer, Nicholette D. Palmer, James T. Willerson, Holly Kramer, Alex N. Parker, Stephan B. Felix, Honghuang Lin, John F. Peden, Norbert Watzinger, I. Mateo Leach, Leena Peltonen, Jayashri Aragam, Ian Ford, Markus Perola, Robert Zweiker, Idris Guessous, Vasyl Pihur, Lars Lind, Igor Rudan, Carl G. P. Platou, Richard J. Rodeheffer, Inga Prokopenko, Andrew Plump, Karin Halina Greiser, Ingrid Borecki, Dorairajan Prabhakaran, Jaap W. Deckers, Iris M. Heid, Bruce M. Psaty, Jan Stritzke, Ivana Kolcic, Leslie J. Raffel, Erik Ingelsson, Ivana Persico, Dabeeru C. Rao, Iftikhar Kullo, J. Wouter Jukema, Asif Rasheed, Johannes Haerting, James F. Wilson, Fulvio Ricceri, Thorsten Reffelmann, Janine F. Felix, Kenneth M. Rice, Margaret M. Redfield, Jasmin Divers, Annika Rosengren, Karl Werdan, Jean-Charles Lambert, Jerome I. Rotter, Gary F. Mitchell, Jeanette M. Stafford, Megan E. Rudock, Donna K. Arnett, Jean-Michel Gaspoz, Siim Sõber, John S. Gottdiener, Jennifer A. Smith, Tunde Salako, Maria Blettner, Jessica D. Faul, Danish Saleheen, Nele Friedrich, Jie Jin Wang, Veikko Salomaa, Peter Kovacs, Jingzhong Ding, Nilesh J. Samani, Philipp S. Wild, Joel N. Hirschhorn, Steven M. Schwartz, Philippe Froguel, John Attia, Peter E. H. Schwarz, Rainer Rettig, John B. Whitfield, Laura J. Scott, Reedik Mägi
Nature Communications, January 2016, Nature
DOI: 10.1038/ncomms10023