What is it about?
GHSQC-TOCSY is a relatively insensitive 2D NMR experiment. Given two coherence transfer experiments, A → B and A → C, it is possible to indirectly determine B ↔ C. Unsymmetrical indirect covariance processing of a 1H–13C GHSQC and a GCOSY spectrum afforded a GHSQC-COSY spectrum, with an information content analogous to a GHSQC-TOCSY experiment.
Featured Image
Why is it important?
GHSQC-TOCSY experiments allow sorting of proton–proton connectivity information as a function of 13C chemical shift. Investigators needing access to GHSQC-TOCSY type data can, access it from more readily acquired 2D NMR data, specifically 1H–13C GHSQC and GCOSY spectra.
Read the Original
This page is a summary of: Using Unsymmetrical Indirect Covariance Processing to Calculate GHSQC-COSY Spectra, Journal of Natural Products, August 2007, American Chemical Society (ACS),
DOI: 10.1021/np070221j.
You can read the full text:
Resources
Contributors
The following have contributed to this page
