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  1. Evaluation of the efficacy of a full-spectrum medicinal cannabis plant extract with less than 0.3% Δ9-tetrahydrocannabinol inin vitromodels of inflammation and excitotoxicity

    Article • January 2024, Cold Spring Harbor Laboratory Press

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  2. Miniature fluorescence sensor for quantitative detection of brain tumour

    Article • Lab on a Chip, January 2024, Royal Society of Chemistry

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  3. Unravelling the role of epigenetic priming in a model of perinatal white matter injury

    Article • Cell Death and Disease, December 2022, Springer Science + Business Media

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  4. Delayed treatments might lead to options to improve the lives of infants who incur brain injury.

    Article • Pediatric Medicine, August 2022, AME Publishing Company

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  5. Studying the immune cells of the ‘little brain’ to develop therapies for brain injury.

    Article • Glia, May 2022, Wiley

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  6. Filling knowledge gaps in what happens inside the infant brain during a bleed

    Article • Pediatric Research, May 2022, Springer Science + Business Media

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  7. miR ‐146b Protects the Perinatal Brain against Microglia‐Induced Hypomyelination

    Article • Annals of Neurology, November 2021, Wiley

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  8. Drinking agricultural groundwater during pregnancy alters offspring brain development; a mouse study

    Article • Ecotoxicology and Environmental Safety, November 2021, Elsevier

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss, Dr G P Gurumurthy

  9. Editorial: Pathomechanisms and Treatments to Protect the Preterm, Fetal Growth Restricted and Neonatal Encephalopathic Brain

    Article • Frontiers in Neurology, September 2021, Frontiers

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  10. Novel Electrode Architecture for Subgaleal Electroencephalography: A Feasibility Study

    Article • August 2021, Cold Spring Harbor Laboratory Press

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  11. A unique cerebellar pattern of microglia activation in a mouse model of encephalopathy of prematurity

    Article • June 2021, Cold Spring Harbor Laboratory Press

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  12. Hypothermia is not therapeutic in a neonatal piglet model of inflammation-sensitized hypoxia–ischemia

    Article • Pediatric Research, May 2021, Springer Science + Business Media

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  13. Stem cells to treat brain injury in babies - can we iron out the details to get this right?

    Article • Biochemical Pharmacology, April 2021, Elsevier

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  14. Construction engineer, menace and protector: the many role for microglia in brain damage in babies.

    Article • Biomolecules, January 2021, MDPI AG

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  15. Neuroprotection offered by mesenchymal stem cells in perinatal brain injury: Role of mitochondria, inflammation, and reactive oxygen species

    Article • Journal of Neurochemistry, January 2021, Wiley

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  16. Brain volumetry in fetuses that deliver very preterm: An MRI pilot study

    Article • NeuroImage Clinical, January 2021, Elsevier

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  17. Midkine: The Who, What, Where, and When of a Promising Neurotrophic Therapy for Perinatal Brain Injury

    Article • Frontiers in Neurology, October 2020, Frontiers

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  18. Perinatal IL-1β-induced inflammation suppresses Tbr2+ intermediate progenitor cell proliferation in the developing hippocampus accompanied by long-term behavioral deficits

    Article • Brain Behavior & Immunity - Health, August 2020, Elsevier

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  19. Cortical Gray Matter Injury in Encephalopathy of Prematurity: Link to Neurodevelopmental Disorders

    Article • Frontiers in Neurology, July 2020, Frontiers

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  20. Serial blood cytokine and chemokine mRNA and microRNA over 48 h are insult specific in a piglet model of inflammation-sensitized hypoxia–ischaemia

    Article • Pediatric Research, June 2020, Springer Science + Business Media

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  21. Perinatal IL-1β-induced Inflammation Suppresses Tbr2+ Intermediate Progenitor Cell Proliferation in the Developing Hippocampus accompanied by Long-Term Behavioral Deficits

    Article • May 2020, Cold Spring Harbor Laboratory Press

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  22. High-Dose Melatonin and Ethanol Excipient Combined with Therapeutic Hypothermia in a Newborn Piglet Asphyxia Model

    Article • Scientific Reports, March 2020, Springer Science + Business Media

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  23. Decreased microglial Wnt/β-catenin signalling drives microglial pro-inflammatory activation in the developing brain

    Article • Brain, October 2019, Oxford University Press (OUP)

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  24. Interneuron Development Is Disrupted in Preterm Brains With Diffuse White Matter Injury: Observations in Mouse and Human

    Article • Frontiers in Physiology, July 2019, Frontiers

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  25. Acute LPS sensitization and continuous infusion exacerbates hypoxic brain injury in a piglet model of neonatal encephalopathy

    Article • Scientific Reports, July 2019, Springer Science + Business Media

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  26. Knowledge Gaps and Emerging Research Areas in Intrauterine Growth Restriction-Associated Brain Injury

    Article • Frontiers in Endocrinology, March 2019, Frontiers

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  27. Lipopolysaccharide‐induced alteration of mitochondrial morphology induces a metabolic shift in microglia modulating the inflammatory response in vitro and in vivo

    Article • Glia, January 2019, Wiley

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  28. Neuroprotection of the preterm brain

    Article • January 2019, Elsevier

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  29. Neuroinflammation in preterm babies and autism spectrum disorders

    Article • Pediatric Research, November 2018, Springer Science + Business Media

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  30. Myelination induction by a histamine H3 receptor antagonist in a mouse model of preterm white matter injury

    Article • Brain Behavior and Immunity, November 2018, Elsevier

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  31. Early origins of neuropsychiatric disorders

    Article • Pediatric Research, October 2018, Springer Science + Business Media

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  32. Epigenome and transcriptome landscapes highlight dual roles of proinflammatory players in a perinatal model of white matter injury

    Article • October 2018, Cold Spring Harbor Laboratory Press

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  33. The Cerebrospinal Fluid Inflammatory Response to Preterm Birth

    Article • Frontiers in Physiology, September 2018, Frontiers

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  34. Loss of the Wnt/β-catenin pathway in microglia of the developing brain drives pro-inflammatory activation leading to white matter injury

    Article • May 2018, Cold Spring Harbor Laboratory Press

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  35. Chorioamnionitis, neuroinflammation, and injury: timing is key in the preterm ovine fetus

    Article • Journal of Neuroinflammation, April 2018, Springer Science + Business Media

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  36. Integrative genomics of microglia implicates DLG4 (PSD95) in the white matter development of preterm infants

    Article • Nature Communications, September 2017, Springer Science + Business Media

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  37. Reactive astrocyte COX2-PGE2 production inhibits oligodendrocyte maturation in neonatal white matter injury

    Article • Glia, August 2017, Wiley

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  38. Role of microglia in a mouse model of paediatric traumatic brain injury

    Article • Brain Behavior and Immunity, July 2017, Elsevier

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  39. Surgery increases cell death and induces changes in gene expression compared with anesthesia alone in the developing piglet brain

    Article • PLoS ONE, March 2017, PLOS

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  40. “Integrative genomics study of microglial transcriptome reveals effect of DLG4 (PSD95) on white matter in preterm infants”

    Article • February 2017, Cold Spring Harbor Laboratory Press

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  41. Dexmedetomidine Combined with Therapeutic Hypothermia Is Associated with Cardiovascular Instability and Neurotoxicity in a Piglet Model of Perinatal Asphyxia

    Article • Developmental Neuroscience, January 2017, Karger Publishers

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  42. Long-Term Neuropathological Changes Associated with Cerebral Palsy in a Nonhuman Primate Model of Hypoxic-Ischemic Encephalopathy

    Article • Developmental Neuroscience, January 2017, Karger Publishers

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  43. Persistently Altered Metabolic Phenotype following Perinatal Excitotoxic Brain Injury

    Article • Developmental Neuroscience, January 2017, Karger Publishers

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  44. Temporal Characterization of Microglia/Macrophage Phenotypes in a Mouse Model of Neonatal Hypoxic-Ischemic Brain Injury

    Article • Frontiers in Cellular Neuroscience, December 2016, Frontiers

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  45. Pro-epileptogenic effects of viral-like inflammation in both mature and immature brains

    Article • Journal of Neuroinflammation, December 2016, Springer Science + Business Media

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  46. Isoflurane Exposure Induces Cell Death, Microglial Activation and Modifies the Expression of Genes Supporting Neurodevelopment and Cognitive Function in the Male Newborn Piglet Brain

    Article • PLoS ONE, November 2016, PLOS

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  47. Contribution of mast cells to injury mechanisms in a mouse model of pediatric traumatic brain injury

    Article • Journal of Neuroscience Research, September 2016, Wiley

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  48. Controversies in preterm brain injury

    Article • Neurobiology of Disease, August 2016, Elsevier

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  49. Inhaled 45–50% argon augments hypothermic brain protection in a piglet model of perinatal asphyxia

    Article • Neurobiology of Disease, March 2016, Elsevier

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  50. Impaired oligodendrocyte maturation in preterm infants: Potential therapeutic targets

    Article • Progress in Neurobiology, January 2016, Elsevier

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  51. Immediate remote ischemic postconditioning after hypoxia ischemia in piglets protects cerebral white matter but not grey matter

    Article • Journal of Cerebral Blood Flow & Metabolism, October 2015, SAGE Publications

    Nicola Robertson, Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  52. Inflammation-induced sensitization of the brain in term infants

    Article • Developmental Medicine & Child Neurology, March 2015, Wiley

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  53. Blood-brain barrier dysfunction in disorders of the developing brain

    Article • Frontiers in Neuroscience, February 2015, Frontiers

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  54. The Anti-Inflammatory Effects of the Small Molecule Pifithrin-µ on BV2 Microglia

    Article • Developmental Neuroscience, January 2015, Karger Publishers

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  55. A Critical Review of Models of Perinatal Infection

    Article • Developmental Neuroscience, January 2015, Karger Publishers

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss, Alistair Gunn

  56. Brain Cell Death Is Reduced With Cooling by 3.5 C to 5 C but Increased With Cooling by 8.5 C in a Piglet Asphyxia Model

    Article • Stroke, November 2014, Wolters Kluwer Health

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  57. HIP/PAP prevents excitotoxic neuronal death and promotes plasticity

    Article • Annals of Clinical and Translational Neurology, October 2014, Wiley

    Dr PARTHIV HALDIPUR, Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  58. Revisiting thyroid hormone treatment to prevent brain damage of prematurity

    Article • Journal of Neuroscience Research, July 2014, Wiley

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  59. Pharmacokinetics of dexmedetomidine combined with therapeutic hypothermia in a piglet asphyxia model

    Article • Acta Anaesthesiologica Scandinavica, April 2014, Wiley

    Nicola Robertson, Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  60. Brain damage of the preterm infant: new insights into the role of inflammation

    Article • Biochemical Society Transactions, March 2014, Portland Press Ltd.

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  61. Failure of thyroid hormone treatment to prevent inflammation-induced white matter injury in the immature brain

    Article • Brain Behavior and Immunity, March 2014, Elsevier

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  62. Stem Cell Therapy for Neonatal Brain Injury

    Article • Clinics in Perinatology, March 2014, Elsevier

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  63. Characterization of phenotype markers and neuronotoxic potential of polarised primary microglia in vitro

    Article • Brain Behavior and Immunity, August 2013, Elsevier

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  64. Bench to Cribside: the Path for Developing a Neuroprotectant

    Article • Translational Stroke Research, December 2012, Springer Science + Business Media

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  65. Melatonin augments hypothermic neuroprotection in a perinatal asphyxia model

    Article • Brain, November 2012, Oxford University Press (OUP)

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  66. Conséquences cérébrales à long terme de l’inflammation périnatale

    Article • Archives de Pédiatrie, September 2012, Elsevier

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  67. Tertiary mechanisms of brain damage: a new hope for treatment of cerebral palsy?

    Article • The Lancet Neurology, June 2012, Elsevier

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  68. Neuroprotection by the histone deacetylase inhibitor trichostatin A in a model of lipopolysaccharide-sensitised neonatal hypoxic-ischaemic brain injury

    Article • Journal of Neuroinflammation, April 2012, Springer Science + Business Media

    MD, PhD Klas Blomgren, Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  69. Effect of maternal administration of allopregnanolone before birth asphyxia on neonatal hippocampal function in the spiny mouse

    Article • Brain Research, January 2012, Elsevier

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  70. Molecular Mechanisms of Neonatal Brain Injury

    Article • Neurology Research International, January 2012, Hindawi Publishing Corporation

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  71. Effects of birth asphyxia on neonatal hippocampal structure and function in the spiny mouse

    Article • International Journal of Developmental Neuroscience, November 2011, Elsevier

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  72. Systemic inflammation disrupts the developmental program of white matter

    Article • Annals of Neurology, July 2011, Wiley

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  73. Systemic Stimulation of TLR2 Impairs Neonatal Mouse Brain Development

    Article • PLoS ONE, May 2011, PLOS

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  74. Corrigendum to “Microglial MyD88 signaling regulates acute neuronal toxicity of LPS-stimulated microglia in vitro” [Brain Behav. Immun. 24 (2010) 776–783]

    Article • Brain Behavior and Immunity, January 2011, Elsevier

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  75. Microglial MyD88 signaling regulates acute neuronal toxicity of LPS-stimulated microglia in vitro

    Article • Brain Behavior and Immunity, July 2010, Elsevier

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss

  76. Behavioural Effects of Near-Term Acute Fetal Hypoxia in a Small Precocial Animal, the Spiny Mouse (Acomys cahirinus)

    Article • Neonatology, January 2010, Karger Publishers

    Lab head - Perinatal Brain Injury Lab Bobbi Fleiss