All Stories

  1. Strategies and mechanisms for endosomal escape of therapeutic nucleic acids
  2. In Vivo Endothelial Cell Gene Silencing by siRNA‐LNPs Tuned with Lipoamino Bundle Chemical and Ligand Targeting
  3. Lipo-Xenopeptide Polyplexes for CRISPR/Cas9 based Gene editing at ultra-low dose
  4. Tumor-targeted PROTAC prodrug nanoplatform enables precise protein degradation and combination cancer therapy
  5. GalNAc- or Mannose-PEG-Functionalized Polyplexes Enable Effective Lectin-Mediated DNA Delivery
  6. Dynamic carriers for therapeutic RNA delivery
  7. Nucleic acid delivery to retinal cells using lipopeptides as a potential tool towards ocular gene therapies
  8. Lipoamino bundle LNPs for efficient mRNA transfection of dendritic cells and macrophages show high spleen selectivity
  9. Transcriptional Targeting of Dendritic Cells Using an Optimized Human Fascin1 Gene Promoter
  10. mCherry on Top: A Positive Read-Out Cellular Platform for Screening DMD Exon Skipping Xenopeptide–PMO Conjugates
  11. From structural design to delivery: mRNA therapeutics for cancer immunotherapy
  12. Receptor-Targeted Carbon Nanodot Delivery through Polymer Caging and Click Chemistry-Supported LRP1 Ligand Attachment
  13. High-resolution bioenergetics correlates the length of continuous protonatable diaminoethane motif of four-armed oligo(ethanamino)amide transfectants to cytotoxicity
  14. Interleukin-6-controlled, mesenchymal stem cell-based sodium/iodide symporter gene therapy improves survival of glioblastoma-bearing mice
  15. Peptide nucleic acid-zirconium coordination nanoparticles
  16. Chemical Evolution of Amphiphilic Xenopeptides for Potentiated Cas9 Ribonucleoprotein Delivery
  17. Iron-Gallic Acid Peptide Nanoparticles as a Versatile Platform for Cellular Delivery with Synergistic ROS Enhancement Effect
  18. Chemical-electron-transfer-based lipopolyplexes for enhanced siRNA delivery
  19. Molecular Chameleon Carriers for Nucleic Acid Delivery: The Sweet Spot Between Lipoplexes and Polyplexes
  20. Mesenchymal Stem Cell–mediated Image-guided Sodium Iodide Symporter (NIS) Gene Therapy Improves Survival of Glioblastoma-bearing Mice
  21. Dual EGFR- and TfR-targeted gene transfer for sodium iodide symporter gene therapy of glioblastoma
  22. Folate Receptor‐Mediated Delivery of Cas9 RNP for Enhanced Immune Checkpoint Disruption in Cancer Cells
  23. Combating Drug Resistance by Exploiting miRNA-200c-Controlled Phase II Detoxification
  24. Biomimetic Mineralization of Iron-Fumarate Nanoparticles for Protective Encapsulation and Intracellular Delivery of Proteins
  25. A Novel Piggyback Strategy for mRNA Delivery Exploiting Adenovirus Entry Biology
  26. Directing the Way—Receptor and Chemical Targeting Strategies for Nucleic Acid Delivery
  27. A Novel Piggyback Strategy for mRNA Delivery Exploiting Adenovirus Entry Biology
  28. Receptor-Targeted Dual pH-Triggered Intracellular Protein Transfer
  29. Targeting nucleic acid-based therapeutics to tumors: Challenges and strategies for polyplexes
  30. Performance of nanoparticles for biomedical applications: The in vitro/in vivo discrepancy
  31. Cross‐Linkable Polyion Complex Micelles from Polypept(o)ide‐Based ABC‐Triblock Copolymers for siRNA Delivery
  32. Non-viral delivery of the CRISPR/Cas system: DNAversusRNAversusRNP
  33. Correction to “Optimizing pDNA Lipo-polyplexes: A Balancing Act between Stability and Cargo Release”
  34. Selective sodium iodide symporter (NIS) gene therapy of glioblastoma mediated by EGFR-targeted lipopolyplexes
  35. NK Cells Armed with Chimeric Antigen Receptors (CAR): Roadblocks to Successful Development
  36. Transferrin Receptor Targeted Polyplexes Completely Comprised of Sequence‐Defined Components
  37. The sodium iodide symporter (NIS): novel applications for radionuclide imaging and treatment
  38. Gene Therapy “Made in Germany”: A Historical Perspective, Analysis of the Status Quo, and Recommendations for Action by the German Society for Gene Therapy
  39. Transient Permeabilization of Living Cells: Combining Shear Flow and Acoustofluidic Trapping for the Facilitated Uptake of Molecules
  40. Optimizing pDNA Lipo-polyplexes: A Balancing Act between Stability and Cargo Release
  41. Regional Hyperthermia Enhances Mesenchymal Stem Cell Recruitment to Tumor Stroma: Implications for Mesenchymal Stem Cell-Based Tumor Therapy
  42. Synergistic Combination of Calcium and Citrate in Mesoporous Nanoparticles Targets Pleural Tumors
  43. Carriers for Nucleic Acid Delivery to the Brain
  44. Controlling Nanoparticle Formulation: A Low-Budget Prototype for the Automation of a Microfluidic Platform
  45. Hyaluronate siRNA nanoparticles with positive charge display rapid attachment to tumor endothelium and penetration into tumors
  46. Versatile, Multifunctional Block Copolymers for the Self-Assembly of Well-Defined, Nontoxic pDNA Polyplexes
  47. A Multistage Cooperative Nanoplatform Enables Intracellular Co‐Delivery of Proteins and Chemotherapeutics for Cancer Therapy
  48. Non-Viral Targeted Nucleic Acid Delivery: Apply Sequences for Optimization
  49. Nucleic Acid-Based Approaches for Tumor Therapy
  50. Particle-Size-Dependent Delivery of Antitumoral miRNA Using Targeted Mesoporous Silica Nanoparticles
  51. Protein-drug conjugate programmed by pH-reversible linker for tumor hypoxia relief and enhanced cancer combination therapy
  52. Optimizing synthetic nucleic acid and protein nanocarriers: The chemical evolution approach
  53. Tuning the Morphological Appearance of Iron(III) Fumarate: Impact on Material Characteristics and Biocompatibility
  54. Delivery of Cas9/sgRNA Ribonucleoprotein Complexes via Hydroxystearyl Oligoamino Amides
  55. Double Click-Functionalized siRNA Polyplexes for Gene Silencing in Epidermal Growth Factor Receptor-Positive Tumor Cells
  56. Artificial peptides for antitumoral siRNA delivery
  57. Effective control of tumor growth through spatial and temporal control of theranostic sodium iodide symporter (NIS) gene expression using a heat-inducible gene promoter in engineered mesenchymal stem cells
  58. Polymer-Based Tumor-targeted Nanosystems
  59. Inducible microRNA-200c decreases motility of breast cancer cells and reduces filamin A
  60. Downregulation of GRK5 hampers the migration of breast cancer cells
  61. A microfluidic approach for sequential assembly of siRNA polyplexes with a defined structure-activity relationship
  62. Co-delivery of pretubulysin and siEG5 to EGFR overexpressing carcinoma cells
  63. Core‐Shell Functionalized Zirconium‐Pemetrexed Coordination Nanoparticles as Carriers with a High Drug Content
  64. Polymeric Carriers for Nucleic Acid Delivery: Current Designs and Future Directions
  65. Supramolecular Assembly of Aminoethylene‐Lipopeptide PMO Conjugates into RNA Splice‐Switching Nanomicelles
  66. Radiation-Induced Amplification of TGFB1-Induced Mesenchymal Stem Cell–Mediated Sodium Iodide Symporter (NIS) Gene 131I Therapy
  67. Combination Chemotherapy of L1210 Tumors in Mice with Pretubulysin and Methotrexate Lipo-Oligomer Nanoparticles
  68. A microfluidic approach for sequential assembly of siRNA polyplexes with defined structure – activity relationship
  69. A microfluidic approach for sequential assembly of siRNA polyplexes with defined structure – activity relationship
  70. IL4‐Receptor‐Targeted Dual Antitumoral Apoptotic Peptide—siRNA Conjugate Lipoplexes
  71. Size tunable nanoparticle formation employing droplet fusion by acoustic streaming applied to polyplexes
  72. Targeting actin inhibits repair of doxorubicin-induced DNA damage: a novel therapeutic approach for combination therapy
  73. Coordinative Binding of Polymers to Metal–Organic Framework Nanoparticles for Control of Interactions at the Biointerface
  74. Targeting APLN/APLNR Improves Antiangiogenic Efficiency and Blunts Proinvasive Side Effects of VEGFA/VEGFR2 Blockade in Glioblastoma
  75. MiRNA-27a sensitizes breast cancer cells to treatment with Selective Estrogen Receptor Modulators
  76. Dual-targeted NIS polyplexes—a theranostic strategy toward tumors with heterogeneous receptor expression
  77. Combined antitumoral effects of pretubulysin and methotrexate
  78. Click-Shielded and Targeted Lipopolyplexes
  79. Combinatorial siRNA Polyplexes for Receptor Targeting
  80. Sequence-Defined Cationic Lipo-Oligomers Containing Unsaturated Fatty Acids for Transfection
  81. Synthesis of Polyethylenimine-Based Nanocarriers for Systemic Tumor Targeting of Nucleic Acids
  82. TGFB1-driven mesenchymal stem cell-mediated NIS gene transfer
  83. External Beam Radiation Therapy Enhances Mesenchymal Stem Cell–Mediated Sodium–Iodide Symporter Gene Delivery
  84. Bioresponsive polyplexes – chemically programmed for nucleic acid delivery
  85. Precise Enzymatic Cleavage Sites for Improved Bioactivity of siRNA Lipo-Polyplexes
  86. Folate receptor-directed orthogonal click-functionalization of siRNA lipopolyplexes for tumor cell killing in vivo
  87. A proteomic analysis of chemoresistance development via sequential treatment with doxorubicin reveals novel players in MCF‑7 breast cancer cells
  88. Epidermal growth factor receptor targeted methotrexate and small interfering RNA co-delivery
  89. Efficient Shielding of Polyplexes Using Heterotelechelic Polysarcosines
  90. Efficient Shielding of Polyplexes Using Heterotelechelic Polysarcosines
  91. A proteomic analysis of an in vitro knock-out of miR-200c
  92. In vivo tracking of adipose tissue grafts with cadmium-telluride quantum dots
  93. Exploring Cytotoxic mRNAs as a Novel Class of Anti-cancer Biotherapeutics
  94. Highly Crystalline Multicolor Carbon Nanodots for Dual-Modal Imaging-Guided Photothermal Therapy of Glioma
  95. Novel PAMAM-PEG-Peptide Conjugates for siRNA Delivery Targeted to the Transferrin and Epidermal Growth Factor Receptors
  96. Reintroducing the Sodium–Iodide Symporter to Anaplastic Thyroid Carcinoma
  97. Solid-phase supported design of carriers for therapeutic nucleic acid delivery
  98. Minicircle Versus Plasmid DNA Delivery by Receptor-Targeted Polyplexes
  99. Augmented glioma-targeted theranostics using multifunctional polymer-coated carbon nanodots
  100. Design of Poly-l -Glutamate-Based Complexes for pDNA Delivery
  101. EGFR-targeted nonviral NIS gene transfer for bioimaging and therapy of disseminated colon cancer metastases
  102. EGFR Targeting and Shielding of pDNA Lipopolyplexes via Bivalent Attachment of a Sequence-Defined PEG Agent
  103. Systemic Delivery of Folate-PEG siRNA Lipopolyplexes with Enhanced Intracellular Stability forIn VivoGene Silencing in Leukemia
  104. Optimized Solid-Phase-Assisted Synthesis of Oleic Acid Containing siRNA Nanocarriers
  105. Lipo-Oligomer Nanoformulations for Targeted Intracellular Protein Delivery
  106. Combining reactive triblock copolymers with functional cross-linkers: A versatile pathway to disulfide stabilized-polyplex libraries and their application as pDNA vaccines
  107. Antitumoral Cascade-Targeting Ligand for IL-6 Receptor-Mediated Gene Delivery to Glioma
  108. Nanoparticle Technology: Having Impact, but Needing Further Optimization
  109. Polyplex Evolution: Understanding Biology, Optimizing Performance
  110. Systemic tumor-targeted sodium iodide symporter (NIS) gene therapy of hepatocellular carcinoma mediated by B6 peptide polyplexes
  111. Influence of Defined Hydrophilic Blocks within Oligoaminoamide Copolymers: Compaction versus Shielding of pDNA Nanoparticles
  112. Design of Poly-l -Glutamate-Based Complexes for pDNA Delivery
  113. Corrigendum to “Acid-labile pHPMA modification of four-arm oligoaminoamide pDNA polyplexes balances shielding and gene transfer activity in vitro and in vivo” [Euro. J. Pharm. Biopharm. 105 (2016) 85–96]
  114. Sequence-Defined Oligoamide Drug Conjugates of Pretubulysin and Methotrexate for Folate Receptor Targeted Cancer Therapy
  115. Imaging and targeted therapy of pancreatic ductal adenocarcinoma using the theranostic sodium iodide symporter (NIS) gene
  116. Monitoring integrity and localization of modified single-stranded RNA oligonucleotides using ultrasensitive fluorescence methods
  117. History of Polymeric Gene Delivery Systems
  118. Multifunctional Nanoparticles by Coordinative Self-Assembly of His-Tagged Units with Metal–Organic Frameworks
  119. Cadmium Telluride Quantum Dots as a Fluorescence Marker for Adipose Tissue Grafts
  120. Microfluidic self-assembly of folate-targeted monomolecular siRNA-lipid nanoparticles
  121. Toward Artificial Immunotoxins: Traceless Reversible Conjugation of RNase A with Receptor Targeting and Endosomal Escape Domains
  122. Tumoral gene silencing by receptor-targeted combinatorial siRNA polyplexes
  123. Intracellular Delivery of Nanobodies for Imaging of Target Proteins in Live Cells
  124. EGF receptor targeted lipo-oligocation polyplexes for antitumoral siRNA and miRNA delivery
  125. Controllable Acoustic Mixing of Fluids in Microchannels for the Fabrication of Therapeutic Nanoparticles
  126. Call for papers: Nanoparticle Development and Applications in Cellular and Molecular Therapies
  127. Acid-labile pHPMA modification of four-arm oligoaminoamide pDNA polyplexes balances shielding and gene transfer activity in vitro and in vivo
  128. Sequence-defined cMET/HGFR-targeted Polymers as Gene Delivery Vehicles for the Theranostic Sodium Iodide Symporter (NIS) Gene
  129. Hypoxia-targeted 131I therapy of hepatocellular cancer after systemic mesenchymal stem cell-mediated sodium iodide symporter gene delivery
  130. Salinomycin co-treatment enhances tamoxifen cytotoxicity in luminal A breast tumor cells by facilitating lysosomal degradation of receptor tyrosine kinases
  131. How to Tackle the Challenge of siRNA Delivery with Sequence-Defined Oligoamino Amides
  132. Post-PEGylation of siRNA Lipo-oligoamino Amide Polyplexes Using Tetra-glutamylated Folic Acid as Ligand for Receptor-Targeted Delivery
  133. Ring-Shaped Microlanes and Chemical Barriers as a Platform for Probing Single-Cell Migration
  134. Specially-Made Lipid-Based Assemblies for Improving Transmembrane Gene Delivery: Comparison of Basic Amino Acid Residue Rich Periphery
  135. Imparting Functionality to MOF Nanoparticles by External Surface Selective Covalent Attachment of Polymers
  136. 493. Nonviral Gene Transfer by Sequence-Defined Proton-Sponges with Combined Nucleic Acid Binding and Endosomal Buffering: Balancing Basicities
  137. Targeted siRNA Delivery Using a Lipo-Oligoaminoamide Nanocore with an Influenza Peptide and Transferrin Shell
  138. Combinatorial Optimization of Sequence-Defined Oligo(ethanamino)amides for Folate Receptor-Targeted pDNA and siRNA Delivery
  139. Dual antitumoral potency of EG5 siRNA nanoplexes armed with cytotoxic bifunctional glutamyl-methotrexate targeting ligand
  140. From Artificial Amino Acids to Sequence-Defined Targeted Oligoaminoamides
  141. DNA as Tunable Adaptor for siRNA Polyplex Stabilization and Functionalization
  142. A Gene Gun-mediated Nonviral RNA trans-splicing Strategy for Col7a1 Repair
  143. Highly efficient siRNA delivery from core–shell mesoporous silica nanoparticles with multifunctional polymer caps
  144. Precise redox-sensitive cleavage sites for improved bioactivity of siRNA lipopolyplexes
  145. pH-Reversible Cationic RNase A Conjugates for Enhanced Cellular Delivery and Tumor Cell Killing
  146. Consecutive salinomycin treatment reduces doxorubicin resistance of breast tumor cells by diminishing drug efflux pump expression and activity
  147. Fast Characterization of Polyplexes by Taylor Dispersion Analysis
  148. Enhanced Intracellular Protein Transduction by Sequence Defined Tetra-Oleoyl Oligoaminoamides Targeted for Cancer Therapy
  149. Sequence-defined nucleic acid carriers combining distinct modules for complexation, shielding, receptor-targeting and endosomal escape
  150. Assessing potential peptide targeting ligands by quantification of cellular adhesion of model nanoparticles under flow conditions
  151. Combination of sequence-defined oligoaminoamides with transferrin-polycation conjugates for receptor-targeted gene delivery
  152. Evaluation of improved PAMAM-G5 conjugates for gene delivery targeted to the transferrin receptor
  153. Peptide-like Polymers Exerting Effective Glioma-Targeted siRNA Delivery and Release for Therapeutic Application
  154. Combining polyethylenimine and Fe(III) for mediating pDNA transfection
  155. Twin disulfides as opportunity for improving stability and transfection efficiency of oligoaminoethane polyplexes
  156. Tumor-targeted Delivery of Anti-microRNA for Cancer Therapy: pHLIP is Key
  157. Nucleic Acid Therapeutics Using Polyplexes: A Journey of 50 Years (and Beyond)
  158. Mesenchymal Stem Cell-Mediated, Tumor Stroma-Targeted Radioiodine Therapy of Metastatic Colon Cancer Using the Sodium Iodide Symporter as Theranostic Gene
  159. Defined Polymeric Materials for Gene Delivery
  160. Dual-Targeted Polyplexes Based on Sequence-Defined Peptide-PEG-Oligoamino Amides
  161. Histidine-rich stabilized polyplexes for cMet-directed tumor-targeted gene transfer
  162. Multifunctional polymer-capped mesoporous silica nanoparticles for pH-responsive targeted drug delivery
  163. Multifunctional Oligoaminoamides for the Receptor-Specific Delivery of Therapeutic RNA
  164. Nucleic Acid Medicines: The Polymer Option
  165. Alternation of histone and DNA methylation in human atherosclerotic carotid plaques
  166. Sequence-defined polymers for the delivery of oligonucleotides
  167. Sequential Salinomycin Treatment Results in Resistance Formation through Clonal Selection of Epithelial-Like Tumor Cells
  168. The Actin Targeting Compound Chondramide Inhibits Breast Cancer Metastasis via Reduction of Cellular Contractility
  169. In vitro and in vivo characterization of the actin polymerizing compound chondramide as an angiogenic inhibitor
  170. Sequence-Defined Oligoaminoamides for the Delivery of siRNAs
  171. Sequence-defined shuttles for targeted nucleic acid and protein delivery
  172. Bioreducible Polycations as Shuttles for Therapeutic Nucleic Acid and Protein Transfection
  173. Targeting the actin cytoskeleton: selective antitumor action via trapping PKCɛ
  174. Synthesis of Core–Shell Graphitic Carbon@Silica Nanospheres with Dual-Ordered Mesopores for Cancer-Targeted Photothermochemotherapy
  175. Stability and activity of hydroxyethyl starch-coated polyplexes in frozen solutions or lyophilizates
  176. Characterization and compatibility of hydroxyethyl starch–polyethylenimine copolymers for DNA delivery
  177. Synthetic Polyglutamylation of Dual-Functional MTX Ligands for Enhanced Combined Cytotoxicity of Poly(I:C) Nanoplexes
  178. Native chemical ligation for conversion of sequence-defined oligomers into targeted pDNA and siRNA carriers
  179. Comb-Like Oligoaminoethane Carriers: Change in Topology Improves pDNA Delivery
  180. Gene Regulation by Intracellular Delivery and Photodegradation of Nanoparticles Containing Small Interfering RNA
  181. Retro-Inverso CendR Peptide-Mediated Polyethyleneimine for Intracranial Glioblastoma-Targeting Gene Therapy
  182. Correlation of Length of Linear Oligo(ethanamino) Amides with Gene Transfer and Cytotoxicity
  183. V-ATPase Inhibition Regulates Anoikis Resistance and Metastasis of Cancer Cells
  184. Fine-tuning of proton sponges by precise diaminoethanes and histidines in pDNA polyplexes
  185. Polymers for Nucleic Acid Transfer—An Overview
  186. Pretubulysin: a new option for the treatment of metastatic cancer
  187. Salinomycin treatment reduces metastatic tumor burden by hampering cancer cell migration
  188. Influences on Cellular Adhesion of Nanoparticles under Blood Flow-Like Conditions
  189. Nucleic Acid Medicines: The Polymer Option
  190. Gene Transfer with Sequence-Defined Oligo(ethanamino)amides Bioreducibly Attached to a Propylenimine Dendrimer Core
  191. The stem cell factor SOX2 regulates the tumorigenic potential in human gastric cancer cells
  192. The proto-oncogene KRAS is targeted by miR-200c
  193. V-ATPase inhibition by archazolid leads to lysosomal dysfunction resulting in impaired cathepsin B activationin vivo
  194. A polyphosphoester conjugate of melphalan as antitumoral agent
  195. Formulation development of lyophilized, long-term stable siRNA/oligoaminoamide polyplexes
  196. Glutathione-sensitive RGD-Poly(ethylene glycol)-SS-Polyethylenimine for intracranial glioblastoma targeted gene delivery
  197. Systemic Image-Guided Liver Cancer Radiovirotherapy Using Dendrimer-Coated Adenovirus Encoding the Sodium Iodide Symporter as Theranostic Gene
  198. De-targeting by miR-143 decreases unwanted transgene expression in non-tumorigenic cells
  199. Generation of a tumor- and tissue-specific episomal non-viral vector system
  200. Comparison of four different particle sizing methods for siRNA polyplex characterization
  201. Gene silencing and antitumoral effects of Eg5 or Ran siRNA oligoaminoamide polyplexes
  202. Characterization of in vivo chemoresistant human hepatocellular carcinoma cells with transendothelial differentiation capacities
  203. The effect of molar mass and degree of hydroxyethylation on the controlled shielding and deshielding of hydroxyethyl starch-coated polyplexes
  204. Stromal Targeting of Sodium Iodide Symporter Using Mesenchymal Stem Cells Allows Enhanced Imaging and Therapy of Hepatocellular Carcinoma
  205. A Comprehensive Gene Expression Analysis of Resistance Formation upon Metronomic Cyclophosphamide Therapy
  206. Endothelial differentiation of adipose-derived mesenchymal stem cells is improved by epigenetic modifying drug BIX-01294
  207. Stabilizing effect of tyrosine trimers on pDNA and siRNA polyplexes
  208. Systemic TNFα Gene Therapy Synergizes With Liposomal Doxorubicine in the Treatment of Metastatic Cancer
  209. Adenoviral Vectors Coated with PAMAM Dendrimer Conjugates Allow CAR Independent Virus Uptake and Targeting to the EGF Receptor
  210. Potent Retro-Inverso d-Peptide for Simultaneous Targeting of Angiogenic Blood Vasculature and Tumor Cells
  211. Biomaterials in RNAi therapeutics: quo vadis?
  212. EGFR-Targeted Adenovirus Dendrimer Coating for Improved Systemic Delivery of the Theranostic NIS Gene
  213. Gene Therapy for Advanced Melanoma: Selective Targeting and Therapeutic Nucleic Acids
  214. In Vivo Imaging Enables High Resolution Preclinical Trials on Patients’ Leukemia Cells Growing in Mice
  215. Sequence-defined four-arm oligo(ethanamino)amides for pDNA and siRNA delivery: Impact of building blocks on efficacy
  216. Stabilization of polyplexes via polymer crosslinking for efficient siRNA delivery
  217. miR-200c Sensitizes Breast Cancer Cells to Doxorubicin Treatment by Decreasing TrkB and Bmi1 Expression
  218. Sequence Defined Disulfide-Linked Shuttle for Strongly Enhanced Intracellular Protein Delivery
  219. Anti-angiogenic effects of the tubulysin precursor pretubulysin and of simplified pretubulysin derivatives
  220. The V-ATPase-Inhibitor Archazolid Abrogates Tumor Metastasis via Inhibition of Endocytic Activation of the Rho-GTPase Rac1
  221. Synthesis of Polyethylenimine-Based Nanocarriers for Systemic Tumor Targeting of Nucleic Acids
  222. Therapeutic plasmid DNA versus siRNA delivery: Common and different tasks for synthetic carriers
  223. Nanosized Multifunctional Polyplexes for Receptor-Mediated SiRNA Delivery
  224. Acid-Labile Traceless Click Linker for Protein Transduction
  225. Tuning Nanoparticle Uptake: Live-Cell Imaging Reveals Two Distinct Endocytosis Mechanisms Mediated by Natural and Artificial EGFR Targeting Ligand
  226. Structure–activity relationships of siRNA carriers based on sequence-defined oligo (ethane amino) amides
  227. New Sequence-Defined Polyaminoamides with Tailored Endosomolytic Properties for Plasmid DNA Delivery
  228. Combinatorial treatment of mammospheres with trastuzumab and salinomycin efficiently targets HER2-positive cancer cells and cancer stem cells
  229. Controlled shielding and deshielding of gene delivery polyplexes using hydroxyethyl starch (HES) and alpha-amylase
  230. Synthesis and characterization of new platinum(II) phosphinate complexes
  231. PolyIC GE11 polyplex inhibits EGFR-overexpressing tumors
  232. Hydrogen Bonding in α-Aminophosphonic Acids
  233. Synthesis of Linear Polyethylenimine and Use in Transfection
  234. Solid-phase-assisted synthesis of targeting peptide–PEG–oligo(ethane amino)amides for receptor-mediated gene delivery
  235. Defined Folate-PEG-siRNA Conjugates for Receptor-specific Gene Silencing
  236. Polymers for siRNA Delivery: Inspired by Viruses to be Targeted, Dynamic, and Precise
  237. Disconnecting the Yin and Yang Relation of Epidermal Growth Factor Receptor (EGFR)-Mediated Delivery: A Fully Synthetic, EGFR-Targeted Gene Transfer System Avoiding Receptor Activation
  238. Image-Guided Tumor-Selective Radioiodine Therapy of Liver Cancer After Systemic Nonviral Delivery of the Sodium Iodide Symporter Gene
  239. Nucleic Acid-Based Therapeutics for Glioblastoma
  240. Nucleic Acid Carriers Based on Precise Polymer Conjugates
  241. Image-guided, Tumor Stroma-targeted 131I Therapy of Hepatocellular Cancer After Systemic Mesenchymal Stem Cell-mediated NIS Gene Delivery
  242. Solid-Phase Synthesis of Sequence-Defined T-, i-, and U-Shape Polymers for pDNA and siRNA Delivery
  243. Invading target cells: multifunctional polymer conjugates as therapeutic nucleic acid carriers
  244. Sustained, high transgene expression in liver with plasmid vectors using optimized promoter-enhancer combinations
  245. To Be Targeted: Is the Magic Bullet Concept a Viable Option for Synthetic Nucleic Acid Therapeutics?
  246. pH-Responsive Release of Acetal-Linked Melittin from SBA-15 Mesoporous Silica
  247. Epidermal Growth Factor–PEG Functionalized PAMAM-Pentaethylenehexamine Dendron for Targeted Gene Delivery Produced by Click Chemistry
  248. Synthesis, NMR-Spectroscopy, and Molecular Structure of a Phosphonyl Ene Diamine
  249. Development of a lyophilized plasmid/LPEI polyplex formulation with long-term stability—A step closer from promising technology to application
  250. Dual-targeted polyplexes: One step towards a synthetic virus for cancer gene therapy
  251. Epidermal Growth Factor Receptor-targeted 131I-therapy of Liver Cancer Following Systemic Delivery of the Sodium Iodide Symporter Gene
  252. Novel Fmoc-Polyamino Acids for Solid-Phase Synthesis of Defined Polyamidoamines
  253. Functional modification of amide-crosslinked oligoethylenimine for improved siRNA delivery
  254. Functional Polymer Conjugates for Medicinal Nucleic Acid Delivery
  255. Live in vivo imaging of Egr-1 promoter activity during neonatal development, liver regeneration and wound healing
  256. Pyridylhydrazone-based PEGylation for pH-reversible lipopolyplex shielding
  257. The establishment of an up-scaled micro-mixer method allows the standardized and reproducible preparation of well-defined plasmid/LPEI polyplexes
  258. EGFR-Homing dsRNA Activates Cancer-Targeted Immune Response and Eliminates Disseminated EGFR-Overexpressing Tumors in Mice
  259. Live-cell imaging and single-particle tracking of polyplex internalization
  260. Impact of Indium-111 Oxine Labelling on Viability of Human Mesenchymal Stem Cells In Vitro, and 3D Cell-Tracking Using SPECT/CT In Vivo
  261. Multifunctional CPP Polymer System for Tumor-Targeted pDNA and siRNA Delivery
  262. Controlled removal of a nonviral episomal vector from transfected cells
  263. Capsomer-Specific Fluorescent Labeling of Adenoviral Vector Particles Allows for Detailed Analysis of Intracellular Particle Trafficking and the Performance of Bioresponsive Bonds for Vector Capsid Modifications
  264. Low generation PAMAM dendrimer and CpG free plasmids allow targeted and extended transgene expression in tumors after systemic delivery
  265. Poly(I:C)-Mediated Tumor Growth Suppression in EGF-Receptor Overexpressing Tumors Using EGF-Polyethylene Glycol-Linear Polyethylenimine as Carrier
  266. The impact of carboxyalkylation of branched polyethylenimine on effectiveness in small interfering RNA delivery
  267. Adenovirus-Derived Vectors for Prostate Cancer Gene Therapy
  268. Clinical Adenoviral Gene Therapy for Prostate Cancer
  269. Bioresponsive polymers for the delivery of therapeutic nucleic acids
  270. In vivo chemoresistance of prostate cancer in metronomic cyclophosphamide therapy
  271. Tf-lipoplex-mediated c-Jun silencing improves neuronal survival following excitotoxic damage in vivo
  272. Monitoring the disassembly of siRNA polyplexes in serum is crucial for predicting their biological efficacy
  273. Peptide- and polymer-based delivery of therapeutic RNA
  274. Photochemical Internalization (PCI): A Technology for Drug Delivery
  275. Chemically Programmed Polymers for Targeted DNA and siRNA Transfection
  276. Improvedin vivogene transfer into tumor tissue by stabilization of pseudodendritic oligoethylenimine-based polyplexes
  277. Hydrophobically Modified Oligoethylenimines as Highly Efficient Transfection Agents for siRNA Delivery
  278. Drug Nanocarriers Labeled With Near-infrared-emitting Quantum Dots (Quantoplexes): Imaging Fast Dynamics of Distribution in Living Animals
  279. Targeted Radioiodine Therapy of Neuroblastoma Tumors following Systemic Nonviral Delivery of the Sodium Iodide Symporter Gene
  280. Influence of the Molecular Weight of Bioreducible Oligoethylenimine Conjugates on the Polyplex Transfection Properties
  281. Synthesis and Biological Evaluation of a Bioresponsive and Endosomolytic siRNA−Polymer Conjugate
  282. Causal Role of Apoptosis-Inducing Factor for Neuronal Cell Death Following Traumatic Brain Injury
  283. Oligoethylenimine-grafted polypropylenimine dendrimers as degradable and biocompatible synthetic vectors for gene delivery
  284. A microscopic view on photo-induced polyplex release from endosomes
  285. Tf-lipoplexes for neuronal siRNA delivery: A promising system to mediate gene silencing in the CNS
  286. Hyperthermia-Induced Targeting of Thermosensitive Gene Carriers to Tumors
  287. Receptor-Targeted Polyplexes for DNA and siRNA Delivery
  288. Extracellular Targeting of Synthetic Therapeutic Nucleic Acid Formulations
  289. Polyhydroxyethylaspartamide-spermine copolymers: Efficient vectors for gene delivery
  290. Click Chemistry for High-Density Biofunctionalization of Mesoporous Silica
  291. Dynamics of photoinduced endosomal release of polyplexes
  292. Nitric oxide—A novel therapeutic for cancer
  293. An Acid Sensitive Ketal-Based Polyethylene Glycol-Oligoethylenimine Copolymer Mediates Improved Transfection Efficiency at Reduced Toxicity
  294. Hyperthermia induced targeting of thermosensitive gene carriers to tumors
  295. The Silent (R)evolution of Polymeric Nucleic Acid Therapeutics
  296. Acetal Linked Oligoethylenimines for Use As pH-Sensitive Gene Carriers
  297. Amine-reactive pyridylhydrazone-based PEG reagents for pH-reversible PEI polyplex shielding
  298. Prolonged gene silencing in hepatoma cells and primary hepatocytes after small interfering RNA delivery with biodegradable poly(β‐amino esters)
  299. Simple Modifications of Branched PEI Lead to Highly Efficient siRNA Carriers with Low Toxicity
  300. Bid-induced release of AIF from mitochondria causes immediate neuronal cell death
  301. Gene therapy progress and prospects: synthetic polymer-based systems
  302. Induction of Apoptosis in Murine Neuroblastoma by Systemic Delivery of Transferrin-Shielded siRNA Polyplexes for Downregulation of Ran
  303. Breathing Life into Polycations:  Functionalization with pH-Responsive Endosomolytic Peptides and Polyethylene Glycol Enables siRNA Delivery
  304. Acrolein: unwanted side product or contribution to antiangiogenic properties of metronomic cyclophosphamide therapy?
  305. Monomolecular Assembly of siRNA and Poly(ethylene glycol)−Peptide Copolymers
  306. Converging Paths of Viral and Non-viral Vector Engineering
  307. Photochemical Enhancement of DNA Delivery by EGF Receptor Targeted Polyplexes
  308. Photochemical Internalization: A New Tool for Drug Delivery
  309. Proteomic Analysis Reveals Differences in Protein Expression in Spheroid versus Monolayer Cultures of Low-Passage Colon Carcinoma Cells
  310. Novel degradable oligoethylenimine acrylate ester-based pseudodendrimers for in vitro and in vivo gene transfer
  311. Novel Biocompatible Cationic Copolymers Based on Polyaspartylhydrazide Being Potent as Gene Vector on Tumor Cells
  312. Electrophoretic purification of tumor-targeted polyethylenimine-based polyplexes reduces toxic side effects in vivo
  313. Synthesis and characterization of chemically condensed oligoethylenimine containing beta-aminopropionamide linkages for siRNA delivery
  314. Corrigendum to “Cellular Dynamics of EGF Receptor–targeted Synthetic Viruses”
  315. An Acetal-Based PEGylation Reagent for pH-Sensitive Shielding of DNA Polyplexes
  316. Cellular Dynamics of EGF Receptor–Targeted Synthetic Viruses
  317. Programmed drug delivery: nanosystems for tumor targeting
  318. Delayed neuronal death after brain trauma involves p53-dependent inhibition of NF-κB transcriptional activity
  319. Cell and Tissue Targeting of Nucleic Acids for Cancer Gene Therapy
  320. Transcriptionally Targeted Nonviral Gene Transfer Using a β-Catenin/TCF-Dependent Promoter in a Series of Different Human Low Passage Colon Cancer Cells
  321. A dimethylmaleic acid–melittin-polylysine conjugate with reduced toxicity, pH-triggered endosomolytic activity and enhanced gene transfer potential
  322. siRNA delivery by a transferrin-associated lipid-based vector: a non-viral strategy to mediate gene silencing
  323. Degradable gene carriers based on oligomerized polyamines
  324. Effects of Raf-1 siRNA on human cerebral microvascular endothelial cells: A potential therapeutic strategy for inhibition of tumor angiogenesis
  325. Optimizing targeted gene delivery: Chemical modification of viral vectors and synthesis of artificial virus vector systems
  326. DNA polyplexes based on degradable oligoethylenimine-derivatives: Combination with EGF receptor targeting and endosomal release functions
  327. Recent Developments in the Application of Plasmid DNA-Based Vectors and Small Interfering RNA Therapeutics for Cancer
  328. The Internalization Route Resulting in Successful Gene Expression Depends on both Cell Line and Polyethylenimine Polyplex Type
  329. Gene Carriers Based on Hexanediol Diacrylate Linked Oligoethylenimine:  Effect of Chemical Structure of Polymer on Biological Properties
  330. pH-responsive shielding of non-viral gene vectors
  331. Induction of activating transcription factor 3 by anoxia is independent of p53 and the hypoxic HIF signalling pathway
  332. Melittin analogs with high lytic activity at endosomal pH enhance transfection with purified targeted PEI polyplexes
  333. Temperature Dependent Gene Expression Induced by PNIPAM-Based Copolymers:  Potential of Hyperthermia in Gene Transfer
  334. Effects of hypoxia and limited diffusion in tumor cell microenvironment on bystander effect of P450 prodrug therapy
  335. Decorated Rods:  A “Bottom-Up” Self-Assembly of Monomolecular DNA Complexes
  336. The Transport of Nanosized Gene Carriers Unraveled by Live-Cell Imaging
  337. Optimized lipopolyplex formulations for gene transfer to human colon carcinoma cells underin vitro conditions
  338. Photochemical Internalization of Transgenes Controlled by the Heat-shock Protein 70 Promoter
  339. EGF Receptor-Targeted Synthetic Double-Stranded RNA Eliminates Glioblastoma, Breast Cancer, and Adenocarcinoma Tumors in Mice
  340. Apoptosis-Inducing Factor Triggered by Poly(ADP-Ribose) Polymerase and Bid Mediates Neuronal Cell Death after Oxygen-Glucose Deprivation and Focal Cerebral Ischemia
  341. Cryoconserved shielded and EGF receptor targeted DNA polyplexes: cellular mechanisms
  342. Specific Targets in Tumor Tissue for the Delivery of Therapeutic Genes
  343. Toward Synthetic Viruses: Endosomal pH-Triggered Deshielding of Targeted Polyplexes Greatly Enhances Gene Transfer in vitro and in vivo
  344. Contribution of academic research to discovery and development of medicines: current status and future opportunities
  345. Opening of Size-Selective Pores in Endosomes during Human Rhinovirus Serotype 2 In Vivo Uncoating Monitored by Single-Organelle Flow Analysis
  346. C- versus N-terminally linked melittin-polyethylenimine conjugates: the site of linkage strongly influences activity of DNA polyplexes
  347. Targeting of Polyplexes: Toward Synthetic Virus Vector Systems
  348. Functional Analysis of Genomic DNA, cDNA, and Nucleotide Sequence of the Mature C-Type Natriuretic Peptide Gene in Vascular Cells
  349. Photochemically Enhanced Gene Delivery of EGF Receptor-targeted DNA Polyplexes
  350. Stabilized Nonviral Formulations for the Delivery of MCP-1 Gene into Cells of the Vasculoendothelial System
  351. Targeted nucleic acid delivery into tumors: new avenues for cancer therapy
  352. In vitro andin vivo delivery of intact BAC DNA– comparison of different methods
  353. Purification of polyethylenimine polyplexes highlights the role of free polycations in gene transfer
  354. Strategies to Improve DNA Polyplexes for in Vivo Gene Transfer: Will “Artificial Viruses” Be the Answer?
  355. Tumor-targeted gene therapy: strategies for the preparation of ligand–polyethylene glycol–polyethylenimine/DNA complexes
  356. Nanoparticles bearing polyethyleneglycol-coupled transferrin as gene carriers: preparation and in vitro evaluation
  357. Tissue-dependent factors affect gene delivery to tumors in vivo
  358. Nonviral gene transfer into fetal mouse livers (a comparison between the cationic polymer PEI and naked DNA)
  359. Optical imaging of transferrin targeted PEI/DNA complexes in living subjects
  360. Novel Shielded Transferrin−Polyethylene Glycol−Polyethylenimine/DNA Complexes for Systemic Tumor-Targeted Gene Transfer
  361. Reactivation of the Mitosis-Promoting Factor in Postmitotic Cardiomyocytes
  362. Specific systemic nonviral gene delivery to human hepatocellular carcinoma xenografts in SCID mice
  363. Tumor-targeted gene delivery of tumor necrosis factor-α induces tumor necrosis and tumor regression without systemic toxicity
  364. Novel colon cancer cell lines leading to better understanding of the diversity of respective primary cancers
  365. Targeting tumors with non-viral gene delivery systems
  366. Somatic gene transfer into the lactating ovine mammary gland
  367. Overcoming the Nuclear Barrier: Cell Cycle Independent Nonviral Gene Transfer with Linear Polyethylenimine or Electroporation
  368. Tumor-targeted gene delivery: an attractive strategy to use highly active effector molecules in cancer treatment
  369. Design and gene delivery activity of modified polyethylenimines
  370. DNA/polyethylenimine transfection particles: Influence of ligands, polymer size, and PEGylation on internalization and gene expression
  371. Different Strategies for Formation of PEGylated EGF-Conjugated PEI/DNA Complexes for Targeted Gene Delivery
  372. Functional maturation of dendritic cells by exposure to CD40L transgenic tumor cells, fibroblasts or keratinocytes
  373. Tumor targeting with surface-shielded ligand–polycation DNA complexes
  374. Immunoadjuvant activity of interferon-γ-liposomes co-administered with influenza vaccines
  375. Different behavior of branched and linear polyethylenimine for gene deliveryin vitro andin vivo
  376. Polyethylenimine/DNA complexes shielded by transferrin target gene expression to tumors after systemic application
  377. Transfection of epithelial cells is enhanced by combined treatment with mannitol and polyethyleneglycol
  378. Xenogenization by tetanus toxoid loading into lymphoblastoid cell lines and primary human tumor cells mediated by polycations and liposomes
  379. Interleukin-2 gene-modified allogeneic melanoma cell vaccines can induce cross-protection against syngeneic tumors in mice
  380. A versatile assay to study cellular uptake of gene transfer complexes by flow cytometry
  381. Efficient In Vitro Transfection of Human Keratinocytes with an Adenovirus-Enhanced Receptor-Mediated System
  382. Cell cycle dependence of gene transfer by lipoplex, polyplex and recombinant adenovirus
  383. Polymer Based Systems for Tumor-Targeted Gene Delivery
  384. Application of membrane-active peptides for nonviral gene delivery
  385. Membrane destabilization for improved cystolic delivery
  386. Mannose Polyethylenimine Conjugates for Targeted DNA Delivery into Dendritic Cells
  387. Differential behaviour of lipid based and polycation based gene transfer systems in transfecting primary human fibroblasts: a potential role of polylysine in nuclear transport
  388. Liposomes as cytokine-supplement in tumor cell-based vaccines
  389. Immunotherapy of Metastatic Malignant Melanoma by a Vaccine Consisting of Autologous Interleukin 2-Transfected Cancer Cells: Outcome of a Phase I Study
  390. PEGylated DNA/transferrin–PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery
  391. Efficient Gene Delivery into Human Dendritic Cells by Adenovirus Polyethylenimine and Mannose Polyethylenimine Transfection
  392. Polycation-based DNA complexes for tumor-targeted gene deliveryin vivo
  393. Development of Transferrin-Polycation/DNA Based Vectors for Gene Delivery to Melanoma Cells
  394. Ligand—Polycation Conjugates for Receptor-Targeted Gene Transfer
  395. Application of membrane-active peptides for drug and gene delivery across cellular membranes
  396. The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells
  397. Influence of the DNA complexation medium on the transfection efficiency of lipospermine/DNA particles
  398. An RGD–Oligolysine Peptide: A Prototype Construct for Integrin-Mediated Gene Delivery
  399. Effects of membrane-active agents in gene delivery
  400. Polylysine-based transfection systems utilizing receptor-mediated delivery
  401. Increase of proliferation rate and enhancement of antitumor cytotoxicity of expanded human CD3+CD56+ immunologic effector cells by receptor-mediated transfection with the interleukin-7 gene
  402. Gene-Modified Dendritic Cells by Receptor-Mediated Transfection
  403. Stabilization of gene delivery systems by freeze-drying
  404. Coupling of cell-binding ligands to polyethylenimine for targeted gene delivery
  405. Phase I study to the immunotherapy of metastatic malignant melanoma by a cancer vaccine consisting of autologous cancer cells transfected with the human IL-2 gene
  406. Glycerol and Polylysine Synergize in Their Ability to Rupture Vesicular Membranes: A Mechanism for Increased Transferrin–Polylysine-Mediated Gene Transfer1
  407. Lymphocyte apoptosis: induction by gene transfer techniques
  408. Nomenclature for Synthetic Gene Delivery Systems
  409. Influence of Membrane-Active Peptides on Lipospermine/DNA Complex Mediated Gene Transfer
  410. The cdc2Ms Kinase Is Differently Regulated in the Cytoplasm and in the Nucleus
  411. In vitro targeting and specific transfection of human neuroblastoma cells by chCE7 antibody-mediated gene transfer
  412. Functional Re-expression of Laminin-5 in Laminin-γ2-deficient Human Keratinocytes Modifies Cell Morphology, Motility, and Adhesion
  413. Activation of the Complement System by Synthetic DNA Complexes: A Potential Barrier for Intravenous Gene Delivery
  414. Extrachromosomal recombination occurs efficiently in cells defective in various DNA repair systems
  415. Glycerol Enhancement of Ligand-Polylysine/DNA Transfection
  416. Developmental and Cell Cycle Regulation of Alfalfa nucMs1, a Plant Homolog of the Yeast Nsr1 and Mammalian Nucleolin
  417. Phase I Study to the Immunotherapy of Metastatic Malignant Melanoma by a Cancer Vaccine Consisting of Autologous Cancer Cells Transfected with the Human IL-2 Gene. University of Vienna, Austria
  418. Developmental and cell cycle regulation of alfalfa nucMs1, a plant homolog of the yeast Nsr1 and mammalian nucleolin.
  419. Virus-mediated release of endosomal content in vitro: different behavior of adenovirus and rhinovirus serotype 2
  420. Receptor-Mediated Gene Transfer into Human T Lymphocytes via Binding of DNA/CD3 Antibody Particles to the CD3 T Cell Receptor Complex
  421. Regulation of the Tissue Factor Promoter in Endothelial Cells
  422. Rhinovirus-mediated endosomal release of transfection complexes.
  423. Psoralen Treatment of Adenovirus Particles Eliminates Virus Replication and Transcription While Maintaining the Endosomolytic Activity of the Virus Capsid
  424. High-Level Expression of Various Apolipoprotein (a) Isoforms by "Transferrinfection": The Role of Kringle IV Sequences in the Extracellular Association with Low-Density Lipoprotein
  425. Synthesis and anti-HIV activity of thiocholesteryl-coupled phosphodiester antisense oligonucleotides incorporated into immunoliposomes
  426. In vivo production of human factor VII in mice after intrasplenic implantation of primary fibroblasts transfected by receptor-mediated, adenovirus-augmented gene delivery.
  427. Chirale Lactole, XI. Eine Methode zur Bestimmung der Absolutkonfiguration chiraler Alkanole
  428. Delivery of drugs, proteins and genes into cells using transferrin as a ligand for receptor-mediated endocytosis
  429. Efficient Foreign Gene Expression in Epstein-Barr Virus-Transformed Human B-Cells
  430. Carbohydrate receptor-mediated gene transfer to human T leukaemic cells
  431. Gene Therapy for B-cell Lymphoma in a SCID Mouse Model using an Immunoglobulin-Regulated Diphtheria Toxin Gene Delivered by a Novel Adenovirus-Polylysine Conjugate
  432. Somatic gene therapy for cancer: the utility of transferrinfection in generating ‘tumor vaccines’
  433. Non-viral approaches to gene therapy
  434. Receptor-mediated Gene Transfer to Airway Epithelial Cells in Primary Culture
  435. Direct In Vivo Gene Transfer to Airway Epithelium Employing Adenovirus–Polylysine–DNA Complexes
  436. [42] Receptor-mediated transport of DNA into eukaryotic cells
  437. Chicken adenovirus (CELO virus) particles augment receptor-mediated DNA delivery to mammalian cells and yield exceptional levels of stable transformants.
  438. Gene transfer into hepatocytes using asialoglycoprotein receptor mediated endocytosis of DNA complexed with an artificial tetra-antennary galactose ligand
  439. Transferrinfection: A Highly Efficient Way to Express Gene Constructs in Eukaryotic Cells
  440. Influenza virus hemagglutinin HA-2 N-terminal fusogenic peptides augment gene transfer by transferrin-polylysine-DNA complexes: toward a synthetic virus-like gene-transfer vehicle.
  441. High-efficiency receptor-mediated delivery of small and large (48 kilobase gene constructs using the endosome-disruption activity of defective or chemically inactivated adenovirus particles.
  442. Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor-mediated gene delivery and expression of transfected genes.
  443. High-Efficiency Gene Transfer Mediated by Adenovirus Coupled to DNA–Polylysine Complexes
  444. Gene Transfer to Respiratory Epithelial Cells via the Receptor-mediated Endocytosis Pathway
  445. Effective incorporation of 2'-O-methyl-oligoribonuclectides into liposomes and enhanced cell association through modification with thiocholesterol
  446. Adenovirus enhancement of transferrin-polylysine-mediated gene delivery.
  447. DNA-binding transferrin conjugates as functional gene-delivery agents: synthesis by linkage of polylysine or ethidium homodimer to the transferrin carbohydrate moiety
  448. 2'-O-methyl, 2'-O-ethyl oligoribonucleotides and phosphorothioate oligodeoxyribonucleotides as inhibitors of the in vitro U7 snRNP-dependent mRNA processing event
  449. Transferrin-polycation-DNA complexes: the effect of polycations on the structure of the complex and DNA delivery to cells.
  450. Pheromone, 3.Mitt.: Eine einfache Methode zur Steuerung der Reduktion von ?-Alkoxy-carbonylverbindungen
  451. A simple procedure for the preparation of protected 2′-O-methyl or 2′-O-ethyl ribonucleoside-3′-O-phosphoramidites
  452. Chemie von a-Aminonitrilen. Aldomerisierung von Glycolaldehyd-phosphat zu racemischen Hexose-2,4,6-triphosphaten und (in Gegenwart von Formaldehyd) racemischen Pentose-2,4-diphosphaten: rac-Allose-2,4,6-triphosphat und rac-Ribose-2,4-diphosphat sind die R
  453. Chemie von α-Aminonitrilen. Aziridin-2-carbonitril, ein Vorläufer von rca-O3-Phosphoserinnitril und Glycolaldehyd-phosphat
  454. Transferrin-polycation-mediated introduction of DNA into human leukemic cells: stimulation by agents that affect the survival of transfected DNA or modulate transferrin receptor levels.
  455. Receptor-mediated endocytosis of transferrin-polycation conjugates: an efficient way to introduce DNA into hematopoietic cells.
  456. Transferrin-polycation conjugates as carriers for DNA uptake into cells.
  457. Ein einfaches Verfahren zur Herstellung anellierter Thiophene
  458. Chirale Lactole, VI. Eine Methode zur Bestimmung der Absolutkonfiguration chiraler α-hydroxysubstituierter Nitrile, Alkine und Aldehyde
  459. Kohlenhydrat-Modelle, I. Kinetische und thermodynamische Effekte bei Acetalisierungsreaktionen enantiomerenreiner Thiolactole
  460. Chirale Lactole, IV. Selektivitäten bei Acetalisierungsreaktionen enantiomerenreiner Lactole am Beispiel von Octahydro-8,9,9-trimethyl-5,8-methano-2H-1-benzopyran-2-ol
  461. Gene Delivery Using Polymer Therapeutics
  462. Nonviral Vector Systems for Cancer Gene Therapy
  463. Optimizing Polyplexes into Synthetic Viruses for Tumor-Targeted Gene Therapy
  464. In Vitro Gene Transfection with Surface-Modified Gelatin Nanoparticles