Contact

All Stories

  1. Evolution of Lipo-Xenopeptide Carriers for siRNA Delivery: Interplay of Stabilizing Subunits

    Article • Bioconjugate Chemistry, March 2025, American Chemical Society (ACS)

    Dr. Ernst Wagner

  2. Ionic Coating of siRNA Polyplexes with cRGD–PEG–Hyaluronic Acid To Modulate Serum Stability and In Vivo Performance

    Article • Biochemistry, March 2025, American Chemical Society (ACS)

    Dr. Ernst Wagner

  3. Dual pH-responsive CRISPR/Cas9 ribonucleoprotein xenopeptide complexes for genome editing

    Article • European Journal of Pharmaceutical Sciences, February 2025, Elsevier

    Dr. Ernst Wagner

  4. New insights for the development of efficient DNA vaccines

    Article • Microbial Biotechnology, November 2024, Wiley

    Dr. Ernst Wagner

  5. Unraveling the metastasis‐preventing effect of miR‐200c in vitro and in vivo

    Article • Molecular Oncology, October 2024, Wiley

    Dr. Ernst Wagner

  6. Strategies and mechanisms for endosomal escape of therapeutic nucleic acids

    Article • Current Opinion in Chemical Biology, August 2024, Elsevier

    Dr. Ernst Wagner

  7. In Vivo Endothelial Cell Gene Silencing by siRNA‐LNPs Tuned with Lipoamino Bundle Chemical and Ligand Targeting

    Article • Small, June 2024, Wiley

    Dr. Ernst Wagner

  8. Dual Effect by Chemical Electron Transfer Enhanced siRNA Lipid Nanoparticles: Reactive Oxygen Species-Triggered Tumor Cell Killing Aggravated by Nrf2 Gene Silencing

    Article • Pharmaceutics, June 2024, MDPI AG

    Dr. Ernst Wagner

  9. Lipo-Xenopeptide Polyplexes for CRISPR/Cas9 based Gene editing at ultra-low dose

    Article • Journal of Controlled Release, June 2024, Elsevier

    Dr. Ernst Wagner

  10. Tumor-targeted PROTAC prodrug nanoplatform enables precise protein degradation and combination cancer therapy

    Article • Acta Pharmacologica Sinica, April 2024, Springer Science + Business Media

    Dr. Ernst Wagner

  11. GalNAc- or Mannose-PEG-Functionalized Polyplexes Enable Effective Lectin-Mediated DNA Delivery

    Article • Bioconjugate Chemistry, March 2024, American Chemical Society (ACS)

    Dr. Ernst Wagner

  12. Dynamic carriers for therapeutic RNA delivery

    Article • Proceedings of the National Academy of Sciences, March 2024, Proceedings of the National Academy of Sciences

    Dr. Ernst Wagner

  13. Nucleic acid delivery to retinal cells using lipopeptides as a potential tool towards ocular gene therapies

    Article • Journal of Colloid and Interface Science, February 2024, Elsevier

    Dr. Ernst Wagner

  14. Crosstalk Between NK Cell Receptors and Tumor Membrane Hsp70‐Derived Peptide: A Combined Computational and Experimental Study

    Article • Advanced Science, January 2024, Wiley

    Dr. Ernst Wagner

  15. Lipoamino bundle LNPs for efficient mRNA transfection of dendritic cells and macrophages show high spleen selectivity

    Article • European Journal of Pharmaceutics and Biopharmaceutics, January 2024, Elsevier

    Dr. Ernst Wagner

  16. Modulating efficacy and cytotoxicity of lipoamino fatty acid nucleic acid carriers using disulfide or hydrophobic spacers

    Article • Nanoscale, January 2024, Royal Society of Chemistry

    Dr. Ernst Wagner

  17. Transcriptional Targeting of Dendritic Cells Using an Optimized Human Fascin1 Gene Promoter

    Article • International Journal of Molecular Sciences, November 2023, MDPI AG

    Dr. Ernst Wagner

  18. mCherry on Top: A Positive Read-Out Cellular Platform for Screening DMD Exon Skipping Xenopeptide–PMO Conjugates

    Article • Bioconjugate Chemistry, November 2023, American Chemical Society (ACS)

    Dr. Ernst Wagner

  19. From structural design to delivery: mRNA therapeutics for cancer immunotherapy

    Article • Exploration, November 2023, Wiley

    Dr. Ernst Wagner

  20. Receptor-Targeted Carbon Nanodot Delivery through Polymer Caging and Click Chemistry-Supported LRP1 Ligand Attachment

    Article • Polymers, October 2023, MDPI AG

    Dr. Ernst Wagner

  21. High-resolution bioenergetics correlates the length of continuous protonatable diaminoethane motif of four-armed oligo(ethanamino)amide transfectants to cytotoxicity

    Article • Journal of Controlled Release, September 2023, Elsevier

    Dr. Ernst Wagner

  22. Interleukin-6-controlled, mesenchymal stem cell-based sodium/iodide symporter gene therapy improves survival of glioblastoma-bearing mice

    Article • Molecular Therapy — Oncolytics, September 2023, Elsevier

    Dr. Ernst Wagner

  23. Peptide nucleic acid-zirconium coordination nanoparticles

    Article • Scientific Reports, August 2023, Springer Science + Business Media

    Dr. Ernst Wagner

  24. Chemical Evolution of Amphiphilic Xenopeptides for Potentiated Cas9 Ribonucleoprotein Delivery

    Article • Journal of the American Chemical Society, July 2023, American Chemical Society (ACS)

    Dr. Ernst Wagner

  25. Iron-Gallic Acid Peptide Nanoparticles as a Versatile Platform for Cellular Delivery with Synergistic ROS Enhancement Effect

    Article • Pharmaceutics, June 2023, MDPI AG

    Dr. Ernst Wagner

  26. Chemical-electron-transfer-based lipopolyplexes for enhanced siRNA delivery

    Article • Cell Reports Physical Science, June 2023, Elsevier

    Dr. Ernst Wagner

  27. Molecular Chameleon Carriers for Nucleic Acid Delivery: The Sweet Spot Between Lipoplexes and Polyplexes

    Article • Advanced Materials, March 2023, Wiley

    Dr. Ernst Wagner

  28. Mesenchymal Stem Cell–mediated Image-guided Sodium Iodide Symporter (NIS) Gene Therapy Improves Survival of Glioblastoma-bearing Mice

    Article • Clinical Cancer Research, December 2022, American Association for Cancer Research (AACR)

    Dr. Ernst Wagner

  29. Dual EGFR- and TfR-targeted gene transfer for sodium iodide symporter gene therapy of glioblastoma

    Article • Molecular Therapy — Oncolytics, December 2022, Elsevier

    Dr. Ernst Wagner

  30. Folate Receptor‐Mediated Delivery of Cas9 RNP for Enhanced Immune Checkpoint Disruption in Cancer Cells

    Article • Small, November 2022, Wiley

    Dr. Ernst Wagner

  31. Combating Drug Resistance by Exploiting miRNA-200c-Controlled Phase II Detoxification

    Article • Cancers, November 2022, MDPI AG

    Dr. Ernst Wagner

  32. Biomimetic Mineralization of Iron-Fumarate Nanoparticles for Protective Encapsulation and Intracellular Delivery of Proteins

    Article • Chemistry of Materials, October 2022, American Chemical Society (ACS)

    Dr. Ernst Wagner

  33. A Novel Piggyback Strategy for mRNA Delivery Exploiting Adenovirus Entry Biology

    Article • Viruses, September 2022, MDPI AG

    Dr. Ernst Wagner

  34. Directing the Way—Receptor and Chemical Targeting Strategies for Nucleic Acid Delivery

    Article • Pharmaceutical Research, September 2022, Springer Science + Business Media

    Dr. Ernst Wagner

  35. A Novel Piggyback Strategy for mRNA Delivery Exploiting Adenovirus Entry Biology

    Article • August 2022, MDPI AG

    Dr. Ernst Wagner

  36. Receptor-Targeted Dual pH-Triggered Intracellular Protein Transfer

    Article • ACS Biomaterials Science & Engineering, July 2022, American Chemical Society (ACS)

    Dr. Ernst Wagner

  37. Targeting nucleic acid-based therapeutics to tumors: Challenges and strategies for polyplexes

    Article • Journal of Controlled Release, June 2022, Elsevier

    Dr. Ernst Wagner

  38. Performance of nanoparticles for biomedical applications: The in vitro/in vivo discrepancy

    Article • Biophysics Reviews, March 2022, American Institute of Physics

    Dr. Ernst Wagner

  39. Cross‐Linkable Polyion Complex Micelles from Polypept(o)ide‐Based ABC‐Triblock Copolymers for siRNA Delivery

    Article • Macromolecular Rapid Communications, January 2022, Wiley

    Dr. Ernst Wagner

  40. Non-viral delivery of the CRISPR/Cas system: DNAversusRNAversusRNP

    Article • Biomaterials Science, January 2022, Royal Society of Chemistry

    Dr. Ernst Wagner

  41. Correction to “Optimizing pDNA Lipo-polyplexes: A Balancing Act between Stability and Cargo Release”

    Article • Biomacromolecules, December 2021, American Chemical Society (ACS)

    Dr. Ernst Wagner

  42. Selective sodium iodide symporter (NIS) gene therapy of glioblastoma mediated by EGFR-targeted lipopolyplexes

    Article • Molecular Therapy — Oncolytics, December 2021, Elsevier

    Dr. Ernst Wagner

  43. NK Cells Armed with Chimeric Antigen Receptors (CAR): Roadblocks to Successful Development

    Article • Cells, December 2021, MDPI AG

    Dr. Ernst Wagner

  44. Transferrin Receptor Targeted Polyplexes Completely Comprised of Sequence‐Defined Components

    Article • Macromolecular Rapid Communications, November 2021, Wiley

    Dr. Ernst Wagner

  45. The sodium iodide symporter (NIS): novel applications for radionuclide imaging and treatment

    Article • Endocrine Related Cancer, October 2021, Bioscientifica

    Dr. Ernst Wagner

  46. Gene Therapy “Made in Germany”: A Historical Perspective, Analysis of the Status Quo, and Recommendations for Action by the German Society for Gene Therapy

    Article • Human Gene Therapy, October 2021, Mary Ann Liebert Inc

    Dr. Ernst Wagner

  47. Transient Permeabilization of Living Cells: Combining Shear Flow and Acoustofluidic Trapping for the Facilitated Uptake of Molecules

    Article • Processes, May 2021, MDPI AG

    Dr. Ernst Wagner

  48. Optimizing pDNA Lipo-polyplexes: A Balancing Act between Stability and Cargo Release

    Article • Biomacromolecules, February 2021, American Chemical Society (ACS)

    Dr. Ernst Wagner

  49. Regional Hyperthermia Enhances Mesenchymal Stem Cell Recruitment to Tumor Stroma: Implications for Mesenchymal Stem Cell-Based Tumor Therapy

    Article • Molecular Therapy, February 2021, Elsevier

    Dr. Ernst Wagner

  50. Synergistic Combination of Calcium and Citrate in Mesoporous Nanoparticles Targets Pleural Tumors

    Article • Chem, February 2021, Elsevier

    Dr. Ernst Wagner

  51. Carriers for Nucleic Acid Delivery to the Brain

    Article • January 2021, Taylor & Francis

    Dr. Ernst Wagner

  52. Controlling Nanoparticle Formulation: A Low-Budget Prototype for the Automation of a Microfluidic Platform

    Article • Processes, January 2021, MDPI AG

    Dr. Ernst Wagner

  53. Hyaluronate siRNA nanoparticles with positive charge display rapid attachment to tumor endothelium and penetration into tumors

    Article • Journal of Controlled Release, January 2021, Elsevier

    Dr. Ernst Wagner

  54. Versatile, Multifunctional Block Copolymers for the Self-Assembly of Well-Defined, Nontoxic pDNA Polyplexes

    Article • ACS Applied Polymer Materials, November 2020, American Chemical Society (ACS)

    Dr. Ernst Wagner

  55. A Multistage Cooperative Nanoplatform Enables Intracellular Co‐Delivery of Proteins and Chemotherapeutics for Cancer Therapy

    Article • Advanced Materials, October 2020, Wiley

    Dr. Ernst Wagner

  56. Non-Viral Targeted Nucleic Acid Delivery: Apply Sequences for Optimization

    Article • Pharmaceutics, September 2020, MDPI AG

    Dr. Ernst Wagner

  57. Nucleic Acid-Based Approaches for Tumor Therapy

    Article • Cells, September 2020, MDPI AG

    Dr. Ernst Wagner

  58. Particle-Size-Dependent Delivery of Antitumoral miRNA Using Targeted Mesoporous Silica Nanoparticles

    Article • Pharmaceutics, June 2020, MDPI AG

    Dr. Ernst Wagner

  59. Protein-drug conjugate programmed by pH-reversible linker for tumor hypoxia relief and enhanced cancer combination therapy

    Article • International Journal of Pharmaceutics, May 2020, Elsevier

    Dr. Ernst Wagner

  60. Optimizing synthetic nucleic acid and protein nanocarriers: The chemical evolution approach

    Article • Advanced Drug Delivery Reviews, April 2020, Elsevier

    Dr. Ernst Wagner

  61. Tuning the Morphological Appearance of Iron(III) Fumarate: Impact on Material Characteristics and Biocompatibility

    Article • Chemistry of Materials, March 2020, American Chemical Society (ACS)

    Christian Hirschle, Dr. Ernst Wagner

  62. Delivery of Cas9/sgRNA Ribonucleoprotein Complexes via Hydroxystearyl Oligoamino Amides

    Article • Bioconjugate Chemistry, February 2020, American Chemical Society (ACS)

    Dr. Ernst Wagner

  63. Double Click-Functionalized siRNA Polyplexes for Gene Silencing in Epidermal Growth Factor Receptor-Positive Tumor Cells

    Article • ACS Biomaterials Science & Engineering, January 2020, American Chemical Society (ACS)

    Dr. Ernst Wagner

  64. Artificial peptides for antitumoral siRNA delivery

    Article • Journal of Materials Chemistry B, January 2020, Royal Society of Chemistry

    Dr. Ernst Wagner

  65. Effective control of tumor growth through spatial and temporal control of theranostic sodium iodide symporter (NIS) gene expression using a heat-inducible gene promoter in engineered mesenchymal stem cells

    Article • Theranostics, January 2020, Ivyspring International Publisher

    Dr. Ernst Wagner

  66. Polymer-Based Tumor-targeted Nanosystems

    Article • January 2020, Springer Science + Business Media

    Dr. Ernst Wagner

  67. Inducible microRNA-200c decreases motility of breast cancer cells and reduces filamin A

    Article • PLOS One, November 2019, PLOS

    Dr. Ernst Wagner

  68. Downregulation of GRK5 hampers the migration of breast cancer cells

    Article • Scientific Reports, October 2019, Springer Science + Business Media

    Dr. Ernst Wagner

  69. A microfluidic approach for sequential assembly of siRNA polyplexes with a defined structure-activity relationship

    Article • October 2019, PeerJ

    Dr. Ernst Wagner

  70. Co-delivery of pretubulysin and siEG5 to EGFR overexpressing carcinoma cells

    Article • International Journal of Pharmaceutics, October 2019, Elsevier

    Dr. Ernst Wagner

  71. Core‐Shell Functionalized Zirconium‐Pemetrexed Coordination Nanoparticles as Carriers with a High Drug Content

    Article • Advanced Therapeutics, September 2019, Wiley

    Dr. Ernst Wagner

  72. Polymeric Carriers for Nucleic Acid Delivery: Current Designs and Future Directions

    Article • Biomacromolecules, September 2019, American Chemical Society (ACS)

    Dr. Ernst Wagner

  73. Supramolecular Assembly of Aminoethylene‐Lipopeptide PMO Conjugates into RNA Splice‐Switching Nanomicelles

    Article • Advanced Functional Materials, September 2019, Wiley

    Dr. Ernst Wagner

  74. Radiation-Induced Amplification of TGFB1-Induced Mesenchymal Stem Cell–Mediated Sodium Iodide Symporter (NIS) Gene 131I Therapy

    Article • Clinical Cancer Research, June 2019, American Association for Cancer Research (AACR)

    Dr. Ernst Wagner

  75. Combination Chemotherapy of L1210 Tumors in Mice with Pretubulysin and Methotrexate Lipo-Oligomer Nanoparticles

    Article • Molecular Pharmaceutics, May 2019, American Chemical Society (ACS)

    Dr. Ernst Wagner

  76. A microfluidic approach for sequential assembly of siRNA polyplexes with defined structure – activity relationship

    Article • April 2019, PeerJ

    Dr. Ernst Wagner

  77. A microfluidic approach for sequential assembly of siRNA polyplexes with defined structure – activity relationship

    Article • April 2019, PeerJ

    Dr. Ernst Wagner

  78. IL4‐Receptor‐Targeted Dual Antitumoral Apoptotic Peptide—siRNA Conjugate Lipoplexes

    Article • Advanced Functional Materials, April 2019, Wiley

    Dr. Ernst Wagner

  79. Size tunable nanoparticle formation employing droplet fusion by acoustic streaming applied to polyplexes

    Article • Journal of Physics D Applied Physics, April 2019, Institute of Physics Publishing

    Dr. Ernst Wagner

  80. Targeting actin inhibits repair of doxorubicin-induced DNA damage: a novel therapeutic approach for combination therapy

    Article • Cell Death and Disease, April 2019, Springer Science + Business Media

    Dr. Ernst Wagner

  81. Coordinative Binding of Polymers to Metal–Organic Framework Nanoparticles for Control of Interactions at the Biointerface

    Article • ACS Nano, March 2019, American Chemical Society (ACS)

    Dr. Ernst Wagner

  82. Targeting APLN/APLNR Improves Antiangiogenic Efficiency and Blunts Proinvasive Side Effects of VEGFA/VEGFR2 Blockade in Glioblastoma

    Article • Cancer Research, February 2019, American Association for Cancer Research (AACR)

    Dr. Ernst Wagner

  83. MiRNA-27a sensitizes breast cancer cells to treatment with Selective Estrogen Receptor Modulators

    Article • The Breast, February 2019, Elsevier

    Dr. Ernst Wagner

  84. Dual-targeted NIS polyplexes—a theranostic strategy toward tumors with heterogeneous receptor expression

    Article • Gene Therapy, January 2019, Springer Science + Business Media

    Dr. Ernst Wagner

  85. Combined antitumoral effects of pretubulysin and methotrexate

    Article • Pharmacology Research & Perspectives, January 2019, Wiley

    Dr. Ernst Wagner

  86. Click-Shielded and Targeted Lipopolyplexes

    Article • January 2019, Springer Science + Business Media

    Dr. Ernst Wagner

  87. Combinatorial siRNA Polyplexes for Receptor Targeting

    Article • January 2019, Springer Science + Business Media

    Dr. Ernst Wagner

  88. Sequence-Defined Cationic Lipo-Oligomers Containing Unsaturated Fatty Acids for Transfection

    Article • January 2019, Springer Science + Business Media

    Dr. Ernst Wagner

  89. Synthesis of Polyethylenimine-Based Nanocarriers for Systemic Tumor Targeting of Nucleic Acids

    Article • January 2019, Springer Science + Business Media

    Dr. Ernst Wagner

  90. TGFB1-driven mesenchymal stem cell-mediated NIS gene transfer

    Article • Endocrine Related Cancer, January 2019, Bioscientifica

    Dr. Ernst Wagner

  91. External Beam Radiation Therapy Enhances Mesenchymal Stem Cell–Mediated Sodium–Iodide Symporter Gene Delivery

    Article • Human Gene Therapy, November 2018, Mary Ann Liebert Inc

    Dr. Ernst Wagner

  92. Bioresponsive polyplexes – chemically programmed for nucleic acid delivery

    Article • Expert Opinion on Drug Delivery, October 2018, Taylor & Francis

    Simone Hager, Dr. Ernst Wagner

  93. Precise Enzymatic Cleavage Sites for Improved Bioactivity of siRNA Lipo-Polyplexes

    Article • Bioconjugate Chemistry, September 2018, American Chemical Society (ACS)

    Dr. Ernst Wagner

  94. Folate receptor-directed orthogonal click-functionalization of siRNA lipopolyplexes for tumor cell killing in vivo

    Article • Biomaterials, September 2018, Elsevier

    Dr. Ernst Wagner

  95. A proteomic analysis of chemoresistance development via sequential treatment with doxorubicin reveals novel players in MCF‑7 breast cancer cells

    Article • International Journal of Molecular Medicine, July 2018, Spandidos Publications

    Dr. Ernst Wagner

  96. Epidermal growth factor receptor targeted methotrexate and small interfering RNA co-delivery

    Article • The Journal of Gene Medicine, July 2018, Wiley

    Dr. Ernst Wagner

  97. Efficient Shielding of Polyplexes Using Heterotelechelic Polysarcosines

    Article • Polymers, June 2018, MDPI AG

    Dr. Ernst Wagner

  98. Efficient Shielding of Polyplexes Using Heterotelechelic Polysarcosines

    Article • May 2018, MDPI AG

    Dr. Ernst Wagner

  99. A proteomic analysis of an in vitro knock-out of miR-200c

    Article • Scientific Reports, May 2018, Springer Science + Business Media

    Dr. Ernst Wagner

  100. In vivo tracking of adipose tissue grafts with cadmium-telluride quantum dots

    Article • Archives of Plastic Surgery, March 2018, Archives of Plastic Surgery (KAMJE)

    Dr. Ernst Wagner

  101. Exploring Cytotoxic mRNAs as a Novel Class of Anti-cancer Biotherapeutics

    Article • Molecular Therapy — Methods & Clinical Development, March 2018, Elsevier

    Dr. Ernst Wagner

  102. Highly Crystalline Multicolor Carbon Nanodots for Dual-Modal Imaging-Guided Photothermal Therapy of Glioma

    Article • ACS Applied Materials & Interfaces, January 2018, American Chemical Society (ACS)

    Dr. Ernst Wagner

  103. Novel PAMAM-PEG-Peptide Conjugates for siRNA Delivery Targeted to the Transferrin and Epidermal Growth Factor Receptors

    Article • Journal of Personalized Medicine, January 2018, MDPI AG

    Dr. Ernst Wagner

  104. Reintroducing the Sodium–Iodide Symporter to Anaplastic Thyroid Carcinoma

    Article • Thyroid, December 2017, Mary Ann Liebert Inc

    Dr. Ernst Wagner

  105. Solid-phase supported design of carriers for therapeutic nucleic acid delivery

    Article • Bioscience Reports, October 2017, Portland Press Ltd.

    Dr. Ernst Wagner

  106. Minicircle Versus Plasmid DNA Delivery by Receptor-Targeted Polyplexes

    Article • Human Gene Therapy, October 2017, Mary Ann Liebert Inc

    Dr. Ernst Wagner

  107. Augmented glioma-targeted theranostics using multifunctional polymer-coated carbon nanodots

    Article • Biomaterials, October 2017, Elsevier

    Dr. Ernst Wagner

  108. Design of Poly-l -Glutamate-Based Complexes for pDNA Delivery

    Article • Macromolecular Bioscience, October 2017, Wiley

    Dr. Ernst Wagner

  109. EGFR-targeted nonviral NIS gene transfer for bioimaging and therapy of disseminated colon cancer metastases

    Article • Oncotarget, September 2017, Impact Journals, LLC

    Dr. Ernst Wagner

  110. EGFR Targeting and Shielding of pDNA Lipopolyplexes via Bivalent Attachment of a Sequence-Defined PEG Agent

    Article • Macromolecular Bioscience, September 2017, Wiley

    Dr. Ernst Wagner

  111. Systemic Delivery of Folate-PEG siRNA Lipopolyplexes with Enhanced Intracellular Stability forIn VivoGene Silencing in Leukemia

    Article • Bioconjugate Chemistry, August 2017, American Chemical Society (ACS)

    Dr. Ernst Wagner

  112. Optimized Solid-Phase-Assisted Synthesis of Oleic Acid Containing siRNA Nanocarriers

    Article • ChemMedChem, August 2017, Wiley

    Dr. Ernst Wagner

  113. Lipo-Oligomer Nanoformulations for Targeted Intracellular Protein Delivery

    Article • Biomacromolecules, July 2017, American Chemical Society (ACS)

    Dr. Ernst Wagner

  114. Combining reactive triblock copolymers with functional cross-linkers: A versatile pathway to disulfide stabilized-polyplex libraries and their application as pDNA vaccines

    Article • Journal of Controlled Release, July 2017, Elsevier

    Dr. Ernst Wagner

  115. Antitumoral Cascade-Targeting Ligand for IL-6 Receptor-Mediated Gene Delivery to Glioma

    Article • Molecular Therapy, July 2017, Elsevier

    Dr. Ernst Wagner

  116. Nanoparticle Technology: Having Impact, but Needing Further Optimization

    Article • Molecular Therapy, July 2017, Elsevier

    Dr. Ernst Wagner

  117. Polyplex Evolution: Understanding Biology, Optimizing Performance

    Article • Molecular Therapy, July 2017, Elsevier

    Dr. Ernst Wagner

  118. Systemic tumor-targeted sodium iodide symporter (NIS) gene therapy of hepatocellular carcinoma mediated by B6 peptide polyplexes

    Article • The Journal of Gene Medicine, May 2017, Wiley

    Dr. Ernst Wagner

  119. Influence of Defined Hydrophilic Blocks within Oligoaminoamide Copolymers: Compaction versus Shielding of pDNA Nanoparticles

    Article • Polymers, April 2017, MDPI AG

    Dr. Ernst Wagner

  120. Design of Poly-l -Glutamate-Based Complexes for pDNA Delivery

    Article • Macromolecular Bioscience, April 2017, Wiley

    Dr. Ernst Wagner

  121. Corrigendum to “Acid-labile pHPMA modification of four-arm oligoaminoamide pDNA polyplexes balances shielding and gene transfer activity in vitro and in vivo” [Euro. J. Pharm. Biopharm. 105 (2016) 85–96]

    Article • European Journal of Pharmaceutics and Biopharmaceutics, April 2017, Elsevier

    Dr. Ernst Wagner

  122. Sequence-Defined Oligoamide Drug Conjugates of Pretubulysin and Methotrexate for Folate Receptor Targeted Cancer Therapy

    Article • Macromolecular Bioscience, March 2017, Wiley

    Dr. Ernst Wagner

  123. Imaging and targeted therapy of pancreatic ductal adenocarcinoma using the theranostic sodium iodide symporter (NIS) gene

    Article • Oncotarget, March 2017, Impact Journals, LLC

    Dr. Ernst Wagner

  124. Monitoring integrity and localization of modified single-stranded RNA oligonucleotides using ultrasensitive fluorescence methods

    Article • PLOS One, March 2017, PLOS

    Dr. Ernst Wagner

  125. History of Polymeric Gene Delivery Systems

    Article • Topics in Current Chemistry, February 2017, Springer Science + Business Media

    Dr. Ernst Wagner

  126. Multifunctional Nanoparticles by Coordinative Self-Assembly of His-Tagged Units with Metal–Organic Frameworks

    Article • Journal of the American Chemical Society, February 2017, American Chemical Society (ACS)

    Dr. Ernst Wagner

  127. Cadmium Telluride Quantum Dots as a Fluorescence Marker for Adipose Tissue Grafts

    Article • Annals of Plastic Surgery, February 2017, Wolters Kluwer Health

    Dr. Ernst Wagner

  128. Microfluidic self-assembly of folate-targeted monomolecular siRNA-lipid nanoparticles

    Article • Nanoscale, January 2017, Royal Society of Chemistry

    Dr. Ernst Wagner

  129. Toward Artificial Immunotoxins: Traceless Reversible Conjugation of RNase A with Receptor Targeting and Endosomal Escape Domains

    Article • Molecular Pharmaceutics, December 2016, American Chemical Society (ACS)

    Dr. Ernst Wagner

  130. Tumoral gene silencing by receptor-targeted combinatorial siRNA polyplexes

    Article • Journal of Controlled Release, December 2016, Elsevier

    Dr. Ernst Wagner

  131. Intracellular Delivery of Nanobodies for Imaging of Target Proteins in Live Cells

    Article • Pharmaceutical Research, October 2016, Springer Science + Business Media

    Dr. Ernst Wagner

  132. EGF receptor targeted lipo-oligocation polyplexes for antitumoral siRNA and miRNA delivery

    Article • Nanotechnology, October 2016, Institute of Physics Publishing

    Dr. Ernst Wagner

  133. Controllable Acoustic Mixing of Fluids in Microchannels for the Fabrication of Therapeutic Nanoparticles

    Article • Micromachines, September 2016, MDPI AG

    Dr. Ernst Wagner

  134. Call for papers: Nanoparticle Development and Applications in Cellular and Molecular Therapies

    Article • Molecular Therapy, August 2016, Elsevier

    Dr Seppo Yla-Herttuala, Dr. Ernst Wagner

  135. Acid-labile pHPMA modification of four-arm oligoaminoamide pDNA polyplexes balances shielding and gene transfer activity in vitro and in vivo

    Article • European Journal of Pharmaceutics and Biopharmaceutics, August 2016, Elsevier

    Dr. Ernst Wagner

  136. Sequence-defined cMET/HGFR-targeted Polymers as Gene Delivery Vehicles for the Theranostic Sodium Iodide Symporter (NIS) Gene

    Article • Molecular Therapy, August 2016, Elsevier

    Dr. Ernst Wagner

  137. Hypoxia-targeted 131I therapy of hepatocellular cancer after systemic mesenchymal stem cell-mediated sodium iodide symporter gene delivery

    Article • Oncotarget, July 2016, Impact Journals, LLC

    Dr. Ernst Wagner

  138. Salinomycin co-treatment enhances tamoxifen cytotoxicity in luminal A breast tumor cells by facilitating lysosomal degradation of receptor tyrosine kinases

    Article • Oncotarget, July 2016, Impact Journals, LLC

    Dr. Ernst Wagner

  139. How to Tackle the Challenge of siRNA Delivery with Sequence-Defined Oligoamino Amides

    Article • Macromolecular Bioscience, June 2016, Wiley

    Dr. Ernst Wagner

  140. Post-PEGylation of siRNA Lipo-oligoamino Amide Polyplexes Using Tetra-glutamylated Folic Acid as Ligand for Receptor-Targeted Delivery

    Article • Molecular Pharmaceutics, May 2016, American Chemical Society (ACS)

    Dr. Ernst Wagner

  141. Ring-Shaped Microlanes and Chemical Barriers as a Platform for Probing Single-Cell Migration

    Article • Scientific Reports, May 2016, Springer Science + Business Media

    Dr. Ernst Wagner

  142. Specially-Made Lipid-Based Assemblies for Improving Transmembrane Gene Delivery: Comparison of Basic Amino Acid Residue Rich Periphery

    Article • Molecular Pharmaceutics, May 2016, American Chemical Society (ACS)

    Dr. Ernst Wagner

  143. Imparting Functionality to MOF Nanoparticles by External Surface Selective Covalent Attachment of Polymers

    Article • Chemistry of Materials, May 2016, American Chemical Society (ACS)

    Dr. Ernst Wagner

  144. 493. Nonviral Gene Transfer by Sequence-Defined Proton-Sponges with Combined Nucleic Acid Binding and Endosomal Buffering: Balancing Basicities

    Article • Molecular Therapy, May 2016, Elsevier

    Dr. Ernst Wagner

  145. Targeted siRNA Delivery Using a Lipo-Oligoaminoamide Nanocore with an Influenza Peptide and Transferrin Shell

    Article • Advanced Healthcare Materials, April 2016, Wiley

    Dr. Ernst Wagner

  146. Combinatorial Optimization of Sequence-Defined Oligo(ethanamino)amides for Folate Receptor-Targeted pDNA and siRNA Delivery

    Article • Bioconjugate Chemistry, January 2016, American Chemical Society (ACS)

    Dr. Ernst Wagner

  147. Dual antitumoral potency of EG5 siRNA nanoplexes armed with cytotoxic bifunctional glutamyl-methotrexate targeting ligand

    Article • Biomaterials, January 2016, Elsevier

    Dr. Ernst Wagner

  148. From Artificial Amino Acids to Sequence-Defined Targeted Oligoaminoamides

    Article • January 2016, Springer Science + Business Media

    Dr. Ernst Wagner

  149. DNA as Tunable Adaptor for siRNA Polyplex Stabilization and Functionalization

    Article • Molecular Therapy — Nucleic Acids, January 2016, Elsevier

    Dr. Ernst Wagner

  150. A Gene Gun-mediated Nonviral RNA trans-splicing Strategy for Col7a1 Repair

    Article • Molecular Therapy — Nucleic Acids, January 2016, Elsevier

    Dr. Ernst Wagner

  151. Highly efficient siRNA delivery from core–shell mesoporous silica nanoparticles with multifunctional polymer caps

    Article • Nanoscale, January 2016, Royal Society of Chemistry

    Dr. Ernst Wagner

  152. Precise redox-sensitive cleavage sites for improved bioactivity of siRNA lipopolyplexes

    Article • Nanoscale, January 2016, Royal Society of Chemistry

    Dr. Ernst Wagner

  153. pH-Reversible Cationic RNase A Conjugates for Enhanced Cellular Delivery and Tumor Cell Killing

    Article • Biomacromolecules, December 2015, American Chemical Society (ACS)

    Dr. Ernst Wagner

  154. Consecutive salinomycin treatment reduces doxorubicin resistance of breast tumor cells by diminishing drug efflux pump expression and activity

    Article • Oncology Reports, December 2015, Spandidos Publications

    Dr. Ernst Wagner

  155. Fast Characterization of Polyplexes by Taylor Dispersion Analysis

    Article • Macromolecules, October 2015, American Chemical Society (ACS)

    Dr. Ernst Wagner

  156. Enhanced Intracellular Protein Transduction by Sequence Defined Tetra-Oleoyl Oligoaminoamides Targeted for Cancer Therapy

    Article • Advanced Functional Materials, September 2015, Wiley

    Dr. Ernst Wagner

  157. Sequence-defined nucleic acid carriers combining distinct modules for complexation, shielding, receptor-targeting and endosomal escape

    Article • Journal of Controlled Release, September 2015, Elsevier

    Dr. Ernst Wagner

  158. Assessing potential peptide targeting ligands by quantification of cellular adhesion of model nanoparticles under flow conditions

    Article • Journal of Controlled Release, September 2015, Elsevier

    Dr. Ernst Wagner

  159. Combination of sequence-defined oligoaminoamides with transferrin-polycation conjugates for receptor-targeted gene delivery

    Article • The Journal of Gene Medicine, August 2015, Wiley

    Dr. Ernst Wagner

  160. Evaluation of improved PAMAM-G5 conjugates for gene delivery targeted to the transferrin receptor

    Article • European Journal of Pharmaceutics and Biopharmaceutics, August 2015, Elsevier

    Dr. Ernst Wagner

  161. Peptide-like Polymers Exerting Effective Glioma-Targeted siRNA Delivery and Release for Therapeutic Application

    Article • Small, July 2015, Wiley

    Dr. Ernst Wagner

  162. Combining polyethylenimine and Fe(III) for mediating pDNA transfection

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, June 2015, Elsevier

    Dr. Ernst Wagner

  163. Twin disulfides as opportunity for improving stability and transfection efficiency of oligoaminoethane polyplexes

    Article • Journal of Controlled Release, May 2015, Elsevier

    Dr. Ernst Wagner

  164. Tumor-targeted Delivery of Anti-microRNA for Cancer Therapy: pHLIP is Key

    Article • Angewandte Chemie, April 2015, Wiley

    Dr. Ernst Wagner

  165. Nucleic Acid Therapeutics Using Polyplexes: A Journey of 50 Years (and Beyond)

    Article • Chemical Reviews, April 2015, American Chemical Society (ACS)

    Dr. Ernst Wagner

  166. Mesenchymal Stem Cell-Mediated, Tumor Stroma-Targeted Radioiodine Therapy of Metastatic Colon Cancer Using the Sodium Iodide Symporter as Theranostic Gene

    Article • Journal of Nuclear Medicine, March 2015, Society of Nuclear Medicine

    Dr. Ernst Wagner

  167. Defined Polymeric Materials for Gene Delivery

    Article • Macromolecular Bioscience, February 2015, Wiley

    Dr. Ernst Wagner

  168. Dual-Targeted Polyplexes Based on Sequence-Defined Peptide-PEG-Oligoamino Amides

    Article • Journal of Pharmaceutical Sciences, February 2015, Elsevier

    Dr. Ernst Wagner

  169. Histidine-rich stabilized polyplexes for cMet-directed tumor-targeted gene transfer

    Article • Nanoscale, January 2015, Royal Society of Chemistry

    Dr. Ernst Wagner

  170. Multifunctional polymer-capped mesoporous silica nanoparticles for pH-responsive targeted drug delivery

    Article • Nanoscale, January 2015, Royal Society of Chemistry

    Dr. Ernst Wagner

  171. Multifunctional Oligoaminoamides for the Receptor-Specific Delivery of Therapeutic RNA

    Article • January 2015, Springer Science + Business Media

    Dr. Ernst Wagner

  172. Nucleic Acid Medicines: The Polymer Option

    Article • January 2015, Springer Science + Business Media

    Dr. Ernst Wagner

  173. Alternation of histone and DNA methylation in human atherosclerotic carotid plaques

    Article • Thrombosis and Haemostasis, January 2015, Thieme Publishing Group

    Dr. Ernst Wagner

  174. Sequence-defined polymers for the delivery of oligonucleotides

    Article • Nanomedicine, December 2014, Future Medicine

    Dr. Ernst Wagner

  175. Sequential Salinomycin Treatment Results in Resistance Formation through Clonal Selection of Epithelial-Like Tumor Cells

    Article • Translational Oncology, December 2014, Elsevier

    Dr. Ernst Wagner

  176. The Actin Targeting Compound Chondramide Inhibits Breast Cancer Metastasis via Reduction of Cellular Contractility

    Article • PLOS One, November 2014, PLOS

    Dr. Ernst Wagner

  177. In vitro and in vivo characterization of the actin polymerizing compound chondramide as an angiogenic inhibitor

    Article • Cardiovascular Research, September 2014, European Society of Cardiology

    Dr. Ernst Wagner

  178. Sequence-Defined Oligoaminoamides for the Delivery of siRNAs

    Article • September 2014, Springer Science + Business Media

    Dr. Ernst Wagner

  179. Sequence-defined shuttles for targeted nucleic acid and protein delivery

    Article • Therapeutic Delivery, September 2014, Future Science

    Dr. Ernst Wagner

  180. Bioreducible Polycations as Shuttles for Therapeutic Nucleic Acid and Protein Transfection

    Article • Antioxidants & Redox Signaling, August 2014, Mary Ann Liebert Inc

    Dr. Ernst Wagner

  181. Targeting the actin cytoskeleton: selective antitumor action via trapping PKCɛ

    Article • Cell Death and Disease, August 2014, Springer Science + Business Media

    Dr. Ernst Wagner

  182. Synthesis of Core–Shell Graphitic Carbon@Silica Nanospheres with Dual-Ordered Mesopores for Cancer-Targeted Photothermochemotherapy

    Article • ACS Nano, July 2014, American Chemical Society (ACS)

    Dr. Ernst Wagner

  183. Stability and activity of hydroxyethyl starch-coated polyplexes in frozen solutions or lyophilizates

    Article • International Journal of Pharmaceutics, July 2014, Elsevier

    Dr Ahmed Besheer, Dr. Ernst Wagner

  184. Characterization and compatibility of hydroxyethyl starch–polyethylenimine copolymers for DNA delivery

    Article • Journal of Biomaterials Science Polymer Edition, May 2014, Taylor & Francis

    Dr Ahmed Besheer, Dr. Ernst Wagner

  185. Synthetic Polyglutamylation of Dual-Functional MTX Ligands for Enhanced Combined Cytotoxicity of Poly(I:C) Nanoplexes

    Article • Molecular Pharmaceutics, May 2014, American Chemical Society (ACS)

    Dr. Ernst Wagner

  186. Native chemical ligation for conversion of sequence-defined oligomers into targeted pDNA and siRNA carriers

    Article • Journal of Controlled Release, April 2014, Elsevier

    Dr. Ernst Wagner

  187. Comb-Like Oligoaminoethane Carriers: Change in Topology Improves pDNA Delivery

    Article • Bioconjugate Chemistry, February 2014, American Chemical Society (ACS)

    Dr. Ernst Wagner

  188. Gene Regulation by Intracellular Delivery and Photodegradation of Nanoparticles Containing Small Interfering RNA

    Article • Macromolecular Bioscience, February 2014, Wiley

    Dr. Ernst Wagner

  189. Retro-Inverso CendR Peptide-Mediated Polyethyleneimine for Intracranial Glioblastoma-Targeting Gene Therapy

    Article • Bioconjugate Chemistry, February 2014, American Chemical Society (ACS)

    Dr. Ernst Wagner

  190. Correlation of Length of Linear Oligo(ethanamino) Amides with Gene Transfer and Cytotoxicity

    Article • ChemMedChem, February 2014, Wiley

    Dr. Ernst Wagner

  191. V-ATPase Inhibition Regulates Anoikis Resistance and Metastasis of Cancer Cells

    Article • Molecular Cancer Therapeutics, January 2014, American Association for Cancer Research (AACR)

    Dr. Ernst Wagner

  192. Fine-tuning of proton sponges by precise diaminoethanes and histidines in pDNA polyplexes

    Article • Nanomedicine Nanotechnology Biology and Medicine, January 2014, Elsevier

    Dr. Ernst Wagner

  193. Polymers for Nucleic Acid Transfer—An Overview

    Article • January 2014, Elsevier

    Dr. Ernst Wagner

  194. Pretubulysin: a new option for the treatment of metastatic cancer

    Article • Cell Death and Disease, January 2014, Springer Science + Business Media

    Dr. Ernst Wagner

  195. Salinomycin treatment reduces metastatic tumor burden by hampering cancer cell migration

    Article • Molecular Cancer, January 2014, Springer Science + Business Media

    Dr. Ernst Wagner

  196. Influences on Cellular Adhesion of Nanoparticles under Blood Flow-Like Conditions

    Article • Biophysical Journal, January 2014, Elsevier

    Dr. Ernst Wagner

  197. Nucleic Acid Medicines: The Polymer Option

    Article • January 2014, Springer Science + Business Media

    Dr. Ernst Wagner

  198. Gene Transfer with Sequence-Defined Oligo(ethanamino)amides Bioreducibly Attached to a Propylenimine Dendrimer Core

    Article • Pharmaceutical Nanotechnology, December 2013, Bentham Science Publishers

    Dr. Ernst Wagner

  199. The stem cell factor SOX2 regulates the tumorigenic potential in human gastric cancer cells

    Article • Carcinogenesis, December 2013, Oxford University Press (OUP)

    Dr. Ernst Wagner

  200. The proto-oncogene KRAS is targeted by miR-200c

    Article • Oncotarget, November 2013, Impact Journals, LLC

    Dr. Ernst Wagner

  201. V-ATPase inhibition by archazolid leads to lysosomal dysfunction resulting in impaired cathepsin B activationin vivo

    Article • International Journal of Cancer, November 2013, Wiley

    Dr. Ernst Wagner

  202. A polyphosphoester conjugate of melphalan as antitumoral agent

    Article • European Journal of Pharmaceutical Sciences, November 2013, Elsevier

    Dr. Ernst Wagner

  203. Formulation development of lyophilized, long-term stable siRNA/oligoaminoamide polyplexes

    Article • European Journal of Pharmaceutics and Biopharmaceutics, October 2013, Elsevier

    Dr. Ernst Wagner

  204. Glutathione-sensitive RGD-Poly(ethylene glycol)-SS-Polyethylenimine for intracranial glioblastoma targeted gene delivery

    Article • The Journal of Gene Medicine, August 2013, Wiley

    Dr. Ernst Wagner

  205. Systemic Image-Guided Liver Cancer Radiovirotherapy Using Dendrimer-Coated Adenovirus Encoding the Sodium Iodide Symporter as Theranostic Gene

    Article • Journal of Nuclear Medicine, July 2013, Society of Nuclear Medicine

    Dr. Ernst Wagner

  206. De-targeting by miR-143 decreases unwanted transgene expression in non-tumorigenic cells

    Article • Gene Therapy, June 2013, Springer Science + Business Media

    Dr. Ernst Wagner

  207. Generation of a tumor- and tissue-specific episomal non-viral vector system

    Article • BMC Biotechnology, June 2013, Springer Science + Business Media

    Dr. Ernst Wagner

  208. Comparison of four different particle sizing methods for siRNA polyplex characterization

    Article • European Journal of Pharmaceutics and Biopharmaceutics, June 2013, Elsevier

    Dr. Ernst Wagner

  209. Gene silencing and antitumoral effects of Eg5 or Ran siRNA oligoaminoamide polyplexes

    Article • Drug Delivery and Translational Research, April 2013, Springer Science + Business Media

    Dr. Ernst Wagner

  210. Characterization of in vivo chemoresistant human hepatocellular carcinoma cells with transendothelial differentiation capacities

    Article • BMC Cancer, April 2013, Springer Science + Business Media

    Dr. Ernst Wagner

  211. The effect of molar mass and degree of hydroxyethylation on the controlled shielding and deshielding of hydroxyethyl starch-coated polyplexes

    Article • Biomaterials, March 2013, Elsevier

    Dr Ahmed Besheer, Dr. Ernst Wagner

  212. Stromal Targeting of Sodium Iodide Symporter Using Mesenchymal Stem Cells Allows Enhanced Imaging and Therapy of Hepatocellular Carcinoma

    Article • Human Gene Therapy, March 2013, Mary Ann Liebert Inc

    Dr. Ernst Wagner

  213. A Comprehensive Gene Expression Analysis of Resistance Formation upon Metronomic Cyclophosphamide Therapy

    Article • Translational Oncology, February 2013, Elsevier

    Dr. Ernst Wagner

  214. Endothelial differentiation of adipose-derived mesenchymal stem cells is improved by epigenetic modifying drug BIX-01294

    Article • European Journal of Cell Biology, February 2013, Elsevier

    Dr. Ernst Wagner

  215. Stabilizing effect of tyrosine trimers on pDNA and siRNA polyplexes

    Article • Biomaterials, February 2013, Elsevier

    Dr. Ernst Wagner

  216. Systemic TNFα Gene Therapy Synergizes With Liposomal Doxorubicine in the Treatment of Metastatic Cancer

    Article • Molecular Therapy, February 2013, Elsevier

    Dr. Ernst Wagner

  217. Adenoviral Vectors Coated with PAMAM Dendrimer Conjugates Allow CAR Independent Virus Uptake and Targeting to the EGF Receptor

    Article • Molecular Pharmaceutics, January 2013, American Chemical Society (ACS)

    Dr. Ernst Wagner

  218. Potent Retro-Inverso d-Peptide for Simultaneous Targeting of Angiogenic Blood Vasculature and Tumor Cells

    Article • Bioconjugate Chemistry, January 2013, American Chemical Society (ACS)

    Dr. Ernst Wagner

  219. Biomaterials in RNAi therapeutics: quo vadis?

    Article • Biomaterials Science, January 2013, Royal Society of Chemistry

    Dr. Ernst Wagner

  220. EGFR-Targeted Adenovirus Dendrimer Coating for Improved Systemic Delivery of the Theranostic NIS Gene

    Article • Molecular Therapy — Nucleic Acids, January 2013, Elsevier

    Dr. Ernst Wagner

  221. Gene Therapy for Advanced Melanoma: Selective Targeting and Therapeutic Nucleic Acids

    Article • Journal of Drug Delivery, January 2013, Hindawi Publishing Corporation

    Dr. Ernst Wagner

  222. In Vivo Imaging Enables High Resolution Preclinical Trials on Patients’ Leukemia Cells Growing in Mice

    Article • PLOS One, December 2012, PLOS

    Dr. Ernst Wagner

  223. Sequence-defined four-arm oligo(ethanamino)amides for pDNA and siRNA delivery: Impact of building blocks on efficacy

    Article • Journal of Controlled Release, December 2012, Elsevier

    Dr. Ernst Wagner

  224. Stabilization of polyplexes via polymer crosslinking for efficient siRNA delivery

    Article • European Journal of Pharmaceutical Sciences, December 2012, Elsevier

    Dr. Ernst Wagner

  225. miR-200c Sensitizes Breast Cancer Cells to Doxorubicin Treatment by Decreasing TrkB and Bmi1 Expression

    Article • PLOS One, November 2012, PLOS

    Dr. Ernst Wagner

  226. Sequence Defined Disulfide-Linked Shuttle for Strongly Enhanced Intracellular Protein Delivery

    Article • Molecular Pharmaceutics, November 2012, American Chemical Society (ACS)

    Dr. Ernst Wagner

  227. Anti-angiogenic effects of the tubulysin precursor pretubulysin and of simplified pretubulysin derivatives

    Article • Bone Marrow Transplantation, October 2012, Wiley

    Dr. Ernst Wagner

  228. The V-ATPase-Inhibitor Archazolid Abrogates Tumor Metastasis via Inhibition of Endocytic Activation of the Rho-GTPase Rac1

    Article • Cancer Research, September 2012, American Association for Cancer Research (AACR)

    Dr. Ernst Wagner

  229. Synthesis of Polyethylenimine-Based Nanocarriers for Systemic Tumor Targeting of Nucleic Acids

    Article • September 2012, Springer Science + Business Media

    Dr. Ernst Wagner

  230. Therapeutic plasmid DNA versus siRNA delivery: Common and different tasks for synthetic carriers

    Article • Journal of Controlled Release, July 2012, Elsevier

    Dr. Ernst Wagner

  231. Nanosized Multifunctional Polyplexes for Receptor-Mediated SiRNA Delivery

    Article • ACS Nano, June 2012, American Chemical Society (ACS)

    Dr. Ernst Wagner

  232. Acid-Labile Traceless Click Linker for Protein Transduction

    Article • Journal of the American Chemical Society, June 2012, American Chemical Society (ACS)

    Dr. Ernst Wagner

  233. Tuning Nanoparticle Uptake: Live-Cell Imaging Reveals Two Distinct Endocytosis Mechanisms Mediated by Natural and Artificial EGFR Targeting Ligand

    Article • Nano Letters, June 2012, American Chemical Society (ACS)

    Dr. Ernst Wagner

  234. Structure–activity relationships of siRNA carriers based on sequence-defined oligo (ethane amino) amides

    Article • Journal of Controlled Release, June 2012, Elsevier

    Dr. Ernst Wagner

  235. New Sequence-Defined Polyaminoamides with Tailored Endosomolytic Properties for Plasmid DNA Delivery

    Article • Bioconjugate Chemistry, May 2012, American Chemical Society (ACS)

    Dr. Ernst Wagner

  236. Combinatorial treatment of mammospheres with trastuzumab and salinomycin efficiently targets HER2-positive cancer cells and cancer stem cells

    Article • International Journal of Cancer, May 2012, Wiley

    Dr. Ernst Wagner

  237. Controlled shielding and deshielding of gene delivery polyplexes using hydroxyethyl starch (HES) and alpha-amylase

    Article • Journal of Controlled Release, April 2012, Elsevier

    Dr Ahmed Besheer, Dr. Ernst Wagner

  238. Synthesis and characterization of new platinum(II) phosphinate complexes

    Article • Journal of Coordination Chemistry, March 2012, Taylor & Francis

    Dr. Ernst Wagner

  239. PolyIC GE11 polyplex inhibits EGFR-overexpressing tumors

    Article • IUBMB Life, February 2012, Wiley

    Dr. Ernst Wagner

  240. Hydrogen Bonding in α-Aminophosphonic Acids

    Article • Phosphorus Sulfur and Silicon and the Related Elements, February 2012, Taylor & Francis

    Dr. Ernst Wagner

  241. Synthesis of Linear Polyethylenimine and Use in Transfection

    Article • Cold Spring Harbor Protocols, February 2012, Cold Spring Harbor Laboratory Press

    Dr. Ernst Wagner

  242. Solid-phase-assisted synthesis of targeting peptide–PEG–oligo(ethane amino)amides for receptor-mediated gene delivery

    Article • Organic & Biomolecular Chemistry, January 2012, Royal Society of Chemistry

    Dr. Ernst Wagner

  243. Defined Folate-PEG-siRNA Conjugates for Receptor-specific Gene Silencing

    Article • Molecular Therapy — Nucleic Acids, January 2012, Elsevier

    Dr. Ernst Wagner

  244. Polymers for siRNA Delivery: Inspired by Viruses to be Targeted, Dynamic, and Precise

    Article • Accounts of Chemical Research, December 2011, American Chemical Society (ACS)

    Dr. Ernst Wagner

  245. Disconnecting the Yin and Yang Relation of Epidermal Growth Factor Receptor (EGFR)-Mediated Delivery: A Fully Synthetic, EGFR-Targeted Gene Transfer System Avoiding Receptor Activation

    Article • Human Gene Therapy, December 2011, Mary Ann Liebert Inc

    Dr. Ernst Wagner

  246. Image-Guided Tumor-Selective Radioiodine Therapy of Liver Cancer After Systemic Nonviral Delivery of the Sodium Iodide Symporter Gene

    Article • Human Gene Therapy, December 2011, Mary Ann Liebert Inc

    Dr. Ernst Wagner

  247. Nucleic Acid-Based Therapeutics for Glioblastoma

    Article • Anti-Cancer Agents in Medicinal Chemistry, October 2011, Bentham Science Publishers

    Dr. Ernst Wagner

  248. Nucleic Acid Carriers Based on Precise Polymer Conjugates

    Article • Bioconjugate Chemistry, September 2011, American Chemical Society (ACS)

    Dr. Ernst Wagner

  249. Image-guided, Tumor Stroma-targeted 131I Therapy of Hepatocellular Cancer After Systemic Mesenchymal Stem Cell-mediated NIS Gene Delivery

    Article • Molecular Therapy, September 2011, Elsevier

    Dr. Ernst Wagner

  250. Solid-Phase Synthesis of Sequence-Defined T-, i-, and U-Shape Polymers for pDNA and siRNA Delivery

    Article • Angewandte Chemie, August 2011, Wiley

    Dr. Ernst Wagner

  251. Invading target cells: multifunctional polymer conjugates as therapeutic nucleic acid carriers

    Article • Frontiers of Chemical Science and Engineering, July 2011, Springer Science + Business Media

    Dr. Ernst Wagner

  252. Sustained, high transgene expression in liver with plasmid vectors using optimized promoter-enhancer combinations

    Article • The Journal of Gene Medicine, July 2011, Wiley

    Dr. Ernst Wagner

  253. To Be Targeted: Is the Magic Bullet Concept a Viable Option for Synthetic Nucleic Acid Therapeutics?

    Article • Human Gene Therapy, July 2011, Mary Ann Liebert Inc

    Dr. Ernst Wagner

  254. pH-Responsive Release of Acetal-Linked Melittin from SBA-15 Mesoporous Silica

    Article • Angewandte Chemie, June 2011, Wiley

    Dr. Ernst Wagner

  255. Epidermal Growth Factor–PEG Functionalized PAMAM-Pentaethylenehexamine Dendron for Targeted Gene Delivery Produced by Click Chemistry

    Article • Biomacromolecules, June 2011, American Chemical Society (ACS)

    Dr. Ernst Wagner

  256. Synthesis, NMR-Spectroscopy, and Molecular Structure of a Phosphonyl Ene Diamine

    Article • Zeitschrift für anorganische und allgemeine Chemie, May 2011, Wiley

    Dr. Ernst Wagner

  257. Development of a lyophilized plasmid/LPEI polyplex formulation with long-term stability—A step closer from promising technology to application

    Article • Journal of Controlled Release, May 2011, Elsevier

    Dr. Ernst Wagner

  258. Dual-targeted polyplexes: One step towards a synthetic virus for cancer gene therapy

    Article • Journal of Controlled Release, May 2011, Elsevier

    Dr. Ernst Wagner

  259. Epidermal Growth Factor Receptor-targeted 131I-therapy of Liver Cancer Following Systemic Delivery of the Sodium Iodide Symporter Gene

    Article • Molecular Therapy, April 2011, Elsevier

    Dr. Ernst Wagner

  260. Novel Fmoc-Polyamino Acids for Solid-Phase Synthesis of Defined Polyamidoamines

    Article • Organic Letters, April 2011, American Chemical Society (ACS)

    Dr. Ernst Wagner

  261. Functional modification of amide-crosslinked oligoethylenimine for improved siRNA delivery

    Article • Reactive and Functional Polymers, March 2011, Elsevier

    Dr. Ernst Wagner

  262. Functional Polymer Conjugates for Medicinal Nucleic Acid Delivery

    Article • January 2011, Springer Science + Business Media

    Dr. Ernst Wagner

  263. Live in vivo imaging of Egr-1 promoter activity during neonatal development, liver regeneration and wound healing

    Article • BMC Developmental Biology, January 2011, Springer Science + Business Media

    Dr. Ernst Wagner

  264. Pyridylhydrazone-based PEGylation for pH-reversible lipopolyplex shielding

    Article • Biomaterials, January 2011, Elsevier

    Dr. Ernst Wagner

  265. The establishment of an up-scaled micro-mixer method allows the standardized and reproducible preparation of well-defined plasmid/LPEI polyplexes

    Article • European Journal of Pharmaceutics and Biopharmaceutics, January 2011, Elsevier

    Dr. Ernst Wagner

  266. EGFR-Homing dsRNA Activates Cancer-Targeted Immune Response and Eliminates Disseminated EGFR-Overexpressing Tumors in Mice

    Article • Clinical Cancer Research, December 2010, American Association for Cancer Research (AACR)

    Dr. Ernst Wagner

  267. Live-cell imaging and single-particle tracking of polyplex internalization

    Article • Drug Discovery Today, December 2010, Elsevier

    Dr. Ernst Wagner

  268. Impact of Indium-111 Oxine Labelling on Viability of Human Mesenchymal Stem Cells In Vitro, and 3D Cell-Tracking Using SPECT/CT In Vivo

    Article • Molecular Imaging and Biology, November 2010, Springer Science + Business Media

    Dr. Ernst Wagner

  269. Multifunctional CPP Polymer System for Tumor-Targeted pDNA and siRNA Delivery

    Article • October 2010, Springer Science + Business Media

    Dr. Ernst Wagner

  270. Controlled removal of a nonviral episomal vector from transfected cells

    Article • Gene, October 2010, Elsevier

    Dr. Ernst Wagner

  271. Capsomer-Specific Fluorescent Labeling of Adenoviral Vector Particles Allows for Detailed Analysis of Intracellular Particle Trafficking and the Performance of Bioresponsive Bonds for Vector Capsid Modifications

    Article • Human Gene Therapy, September 2010, Mary Ann Liebert Inc

    Dr. Ernst Wagner

  272. Low generation PAMAM dendrimer and CpG free plasmids allow targeted and extended transgene expression in tumors after systemic delivery

    Article • Journal of Controlled Release, August 2010, Elsevier

    Dr. Ernst Wagner

  273. Poly(I:C)-Mediated Tumor Growth Suppression in EGF-Receptor Overexpressing Tumors Using EGF-Polyethylene Glycol-Linear Polyethylenimine as Carrier

    Article • Pharmaceutical Research, August 2010, Springer Science + Business Media

    Dr. Ernst Wagner

  274. The impact of carboxyalkylation of branched polyethylenimine on effectiveness in small interfering RNA delivery

    Article • The Journal of Gene Medicine, August 2010, Wiley

    Dr. Ernst Wagner

  275. Adenovirus-Derived Vectors for Prostate Cancer Gene Therapy

    Article • Human Gene Therapy, July 2010, Mary Ann Liebert Inc

    Dr. Ernst Wagner

  276. Clinical Adenoviral Gene Therapy for Prostate Cancer

    Article • Human Gene Therapy, July 2010, Mary Ann Liebert Inc

    Dr. Ernst Wagner

  277. Bioresponsive polymers for the delivery of therapeutic nucleic acids

    Article • Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology, June 2010, Wiley

    Dr. Ernst Wagner

  278. In vivo chemoresistance of prostate cancer in metronomic cyclophosphamide therapy

    Article • Journal of Proteomics, May 2010, Elsevier

    Dr. Ernst Wagner

  279. Tf-lipoplex-mediated c-Jun silencing improves neuronal survival following excitotoxic damage in vivo

    Article • Journal of Controlled Release, March 2010, Elsevier

    Dr. Ernst Wagner

  280. Monitoring the disassembly of siRNA polyplexes in serum is crucial for predicting their biological efficacy

    Article • Journal of Controlled Release, January 2010, Elsevier

    Dr. Ernst Wagner

  281. Peptide- and polymer-based delivery of therapeutic RNA

    Article • Soft Matter, January 2010, Royal Society of Chemistry

    Dr. Ernst Wagner

  282. Photochemical Internalization (PCI): A Technology for Drug Delivery

    Article • January 2010, Springer Science + Business Media

    Pål Kristian Selbo, Dr. Ernst Wagner

  283. Chemically Programmed Polymers for Targeted DNA and siRNA Transfection

    Article • January 2010, Springer Science + Business Media

    Dr. Ernst Wagner

  284. Improvedin vivogene transfer into tumor tissue by stabilization of pseudodendritic oligoethylenimine-based polyplexes

    Article • The Journal of Gene Medicine, January 2010, Wiley

    Dr. Ernst Wagner

  285. Hydrophobically Modified Oligoethylenimines as Highly Efficient Transfection Agents for siRNA Delivery

    Article • Bioconjugate Chemistry, November 2009, American Chemical Society (ACS)

    Dr. Ernst Wagner

  286. Drug Nanocarriers Labeled With Near-infrared-emitting Quantum Dots (Quantoplexes): Imaging Fast Dynamics of Distribution in Living Animals

    Article • Molecular Therapy, November 2009, Elsevier

    Dr. Ernst Wagner

  287. Targeted Radioiodine Therapy of Neuroblastoma Tumors following Systemic Nonviral Delivery of the Sodium Iodide Symporter Gene

    Article • Clinical Cancer Research, September 2009, American Association for Cancer Research (AACR)

    Dr. Ernst Wagner

  288. Influence of the Molecular Weight of Bioreducible Oligoethylenimine Conjugates on the Polyplex Transfection Properties

    Article • The AAPS Journal, June 2009, Springer Science + Business Media

    Dr. Ernst Wagner

  289. Synthesis and Biological Evaluation of a Bioresponsive and Endosomolytic siRNA−Polymer Conjugate

    Article • Molecular Pharmaceutics, April 2009, American Chemical Society (ACS)

    Dr. Ernst Wagner

  290. Causal Role of Apoptosis-Inducing Factor for Neuronal Cell Death Following Traumatic Brain Injury

    Article • American Journal Of Pathology, December 2008, Elsevier

    MD, PhD Klas Blomgren, Dr. Ernst Wagner

  291. Oligoethylenimine-grafted polypropylenimine dendrimers as degradable and biocompatible synthetic vectors for gene delivery

    Article • Journal of Controlled Release, December 2008, Elsevier

    Dr. Ernst Wagner

  292. A microscopic view on photo-induced polyplex release from endosomes

    Article • Journal of Controlled Release, December 2008, Elsevier

    Dr. Ernst Wagner

  293. Tf-lipoplexes for neuronal siRNA delivery: A promising system to mediate gene silencing in the CNS

    Article • Journal of Controlled Release, December 2008, Elsevier

    Dr. Ernst Wagner

  294. Hyperthermia-Induced Targeting of Thermosensitive Gene Carriers to Tumors

    Article • Human Gene Therapy, November 2008, Mary Ann Liebert Inc

    Dr. Ernst Wagner

  295. Receptor-Targeted Polyplexes for DNA and siRNA Delivery

    Article • October 2008, Taylor & Francis

    Dr. Ernst Wagner

  296. Extracellular Targeting of Synthetic Therapeutic Nucleic Acid Formulations

    Article • Current Gene Therapy, October 2008, Bentham Science Publishers

    Dr. Ernst Wagner

  297. Polyhydroxyethylaspartamide-spermine copolymers: Efficient vectors for gene delivery

    Article • Journal of Controlled Release, October 2008, Elsevier

    Dr. Ernst Wagner

  298. Click Chemistry for High-Density Biofunctionalization of Mesoporous Silica

    Article • Journal of the American Chemical Society, September 2008, American Chemical Society (ACS)

    Dr. Ernst Wagner

  299. Dynamics of photoinduced endosomal release of polyplexes

    Article • Journal of Controlled Release, September 2008, Elsevier

    Dr. Ernst Wagner

  300. Nitric oxide—A novel therapeutic for cancer

    Article • Nitric Oxide, September 2008, Elsevier

    Dr. Ernst Wagner

  301. An Acid Sensitive Ketal-Based Polyethylene Glycol-Oligoethylenimine Copolymer Mediates Improved Transfection Efficiency at Reduced Toxicity

    Article • Pharmaceutical Research, August 2008, Springer Science + Business Media

    Dr. Ernst Wagner

  302. Hyperthermia induced targeting of thermosensitive gene carriers to tumors

    Article • Human Gene Therapy, August 2008, Mary Ann Liebert Inc

    Dr. Ernst Wagner

  303. The Silent (R)evolution of Polymeric Nucleic Acid Therapeutics

    Article • Pharmaceutical Research, August 2008, Springer Science + Business Media

    Dr. Ernst Wagner

  304. Acetal Linked Oligoethylenimines for Use As pH-Sensitive Gene Carriers

    Article • Bioconjugate Chemistry, August 2008, American Chemical Society (ACS)

    Dr. Ernst Wagner

  305. Amine-reactive pyridylhydrazone-based PEG reagents for pH-reversible PEI polyplex shielding

    Article • European Journal of Pharmaceutical Sciences, August 2008, Elsevier

    Dr. Ernst Wagner

  306. Prolonged gene silencing in hepatoma cells and primary hepatocytes after small interfering RNA delivery with biodegradable poly(β‐amino esters)

    Article • The Journal of Gene Medicine, July 2008, Wiley

    Dr. Ernst Wagner

  307. Simple Modifications of Branched PEI Lead to Highly Efficient siRNA Carriers with Low Toxicity

    Article • Bioconjugate Chemistry, July 2008, American Chemical Society (ACS)

    Dr. Ernst Wagner

  308. Bid-induced release of AIF from mitochondria causes immediate neuronal cell death

    Article • Cell Death and Differentiation, June 2008, Springer Science + Business Media

    Dr. Ernst Wagner

  309. Gene therapy progress and prospects: synthetic polymer-based systems

    Article • Gene Therapy, June 2008, Springer Science + Business Media

    Dr. Ernst Wagner

  310. Induction of Apoptosis in Murine Neuroblastoma by Systemic Delivery of Transferrin-Shielded siRNA Polyplexes for Downregulation of Ran

    Article • Oligonucleotides, June 2008, Mary Ann Liebert Inc

    Dr. Ernst Wagner

  311. Breathing Life into Polycations:  Functionalization with pH-Responsive Endosomolytic Peptides and Polyethylene Glycol Enables siRNA Delivery

    Article • Journal of the American Chemical Society, March 2008, American Chemical Society (ACS)

    Dr. Ernst Wagner

  312. Acrolein: unwanted side product or contribution to antiangiogenic properties of metronomic cyclophosphamide therapy?

    Article • Journal of Cellular and Molecular Medicine, February 2008, Wiley

    Dr. Ernst Wagner

  313. Monomolecular Assembly of siRNA and Poly(ethylene glycol)−Peptide Copolymers

    Article • Biomacromolecules, February 2008, American Chemical Society (ACS)

    Dr. Ernst Wagner

  314. Converging Paths of Viral and Non-viral Vector Engineering

    Article • Molecular Therapy, January 2008, Elsevier

    Dr. Ernst Wagner

  315. Photochemical Enhancement of DNA Delivery by EGF Receptor Targeted Polyplexes

    Article • January 2008, Springer Science + Business Media

    Dr. Ernst Wagner

  316. Photochemical Internalization: A New Tool for Drug Delivery

    Article • Current Pharmaceutical Biotechnology, December 2007, Bentham Science Publishers

    Pål Kristian Selbo, Dr. Ernst Wagner

  317. Proteomic Analysis Reveals Differences in Protein Expression in Spheroid versus Monolayer Cultures of Low-Passage Colon Carcinoma Cells

    Article • Journal of Proteome Research, November 2007, American Chemical Society (ACS)

    Dr. Ernst Wagner

  318. Novel degradable oligoethylenimine acrylate ester-based pseudodendrimers for in vitro and in vivo gene transfer

    Article • Gene Therapy, October 2007, Springer Science + Business Media

    Dr. Ernst Wagner

  319. Novel Biocompatible Cationic Copolymers Based on Polyaspartylhydrazide Being Potent as Gene Vector on Tumor Cells

    Article • Pharmaceutical Research, October 2007, Springer Science + Business Media

    Dr. Ernst Wagner

  320. Electrophoretic purification of tumor-targeted polyethylenimine-based polyplexes reduces toxic side effects in vivo

    Article • Journal of Controlled Release, October 2007, Elsevier

    Dr. Ernst Wagner

  321. Synthesis and characterization of chemically condensed oligoethylenimine containing beta-aminopropionamide linkages for siRNA delivery

    Article • Biomaterials, September 2007, Elsevier

    Dr. Ernst Wagner

  322. Corrigendum to “Cellular Dynamics of EGF Receptor–targeted Synthetic Viruses”

    Article • Molecular Therapy, September 2007, Elsevier

    Dr. Ernst Wagner

  323. An Acetal-Based PEGylation Reagent for pH-Sensitive Shielding of DNA Polyplexes

    Article • Bioconjugate Chemistry, July 2007, American Chemical Society (ACS)

    Dr. Ernst Wagner

  324. Cellular Dynamics of EGF Receptor–Targeted Synthetic Viruses

    Article • Molecular Therapy, July 2007, Elsevier

    Dr. Ernst Wagner

  325. Programmed drug delivery: nanosystems for tumor targeting

    Article • Expert Opinion on Biological Therapy, May 2007, Informa Healthcare

    Dr. Ernst Wagner

  326. Delayed neuronal death after brain trauma involves p53-dependent inhibition of NF-κB transcriptional activity

    Article • Cell Death and Differentiation, April 2007, Springer Science + Business Media

    Dr. Ernst Wagner

  327. Cell and Tissue Targeting of Nucleic Acids for Cancer Gene Therapy

    Article • Pharmaceutical Research, March 2007, Springer Science + Business Media

    Dr. Ernst Wagner

  328. Transcriptionally Targeted Nonviral Gene Transfer Using a β-Catenin/TCF-Dependent Promoter in a Series of Different Human Low Passage Colon Cancer Cells

    Article • Molecular Pharmaceutics, February 2007, American Chemical Society (ACS)

    Dr. Ernst Wagner

  329. A dimethylmaleic acid–melittin-polylysine conjugate with reduced toxicity, pH-triggered endosomolytic activity and enhanced gene transfer potential

    Article • The Journal of Gene Medicine, January 2007, Wiley

    Dr. Ernst Wagner

  330. siRNA delivery by a transferrin-associated lipid-based vector: a non-viral strategy to mediate gene silencing

    Article • The Journal of Gene Medicine, January 2007, Wiley

    Dr. Ernst Wagner

  331. Degradable gene carriers based on oligomerized polyamines

    Article • European Journal of Pharmaceutical Sciences, December 2006, Elsevier

    Dr. Ernst Wagner

  332. Effects of Raf-1 siRNA on human cerebral microvascular endothelial cells: A potential therapeutic strategy for inhibition of tumor angiogenesis

    Article • Brain Research, December 2006, Elsevier

    Dr. Ernst Wagner

  333. Optimizing targeted gene delivery: Chemical modification of viral vectors and synthesis of artificial virus vector systems

    Article • The AAPS Journal, December 2006, Springer Science + Business Media

    Dr. Ernst Wagner

  334. DNA polyplexes based on degradable oligoethylenimine-derivatives: Combination with EGF receptor targeting and endosomal release functions

    Article • Journal of Controlled Release, November 2006, Elsevier

    Dr. Ernst Wagner

  335. Recent Developments in the Application of Plasmid DNA-Based Vectors and Small Interfering RNA Therapeutics for Cancer

    Article • Human Gene Therapy, November 2006, Mary Ann Liebert Inc

    Dr. Ernst Wagner

  336. The Internalization Route Resulting in Successful Gene Expression Depends on both Cell Line and Polyethylenimine Polyplex Type

    Article • Molecular Therapy, November 2006, Elsevier

    Dr. Ernst Wagner

  337. Gene Carriers Based on Hexanediol Diacrylate Linked Oligoethylenimine:  Effect of Chemical Structure of Polymer on Biological Properties

    Article • Bioconjugate Chemistry, September 2006, American Chemical Society (ACS)

    Dr. Ernst Wagner

  338. pH-responsive shielding of non-viral gene vectors

    Article • Expert Opinion on Drug Delivery, September 2006, Informa Healthcare

    Dr. Ernst Wagner

  339. Induction of activating transcription factor 3 by anoxia is independent of p53 and the hypoxic HIF signalling pathway

    Article • Oncogene, July 2006, Springer Science + Business Media

    Dr. Ernst Wagner

  340. Melittin analogs with high lytic activity at endosomal pH enhance transfection with purified targeted PEI polyplexes

    Article • Journal of Controlled Release, May 2006, Elsevier

    Dr. Ernst Wagner

  341. Temperature Dependent Gene Expression Induced by PNIPAM-Based Copolymers:  Potential of Hyperthermia in Gene Transfer

    Article • Bioconjugate Chemistry, May 2006, American Chemical Society (ACS)

    Dr. Ernst Wagner

  342. Effects of hypoxia and limited diffusion in tumor cell microenvironment on bystander effect of P450 prodrug therapy

    Article • Cancer Gene Therapy, March 2006, Springer Science + Business Media

    Dr. Ernst Wagner

  343. Decorated Rods:  A “Bottom-Up” Self-Assembly of Monomolecular DNA Complexes

    Article • The Journal of Physical Chemistry B, March 2006, American Chemical Society (ACS)

    Dr. Ernst Wagner

  344. The Transport of Nanosized Gene Carriers Unraveled by Live-Cell Imaging

    Article • Angewandte Chemie, February 2006, Wiley

    Dr. Ernst Wagner

  345. Optimized lipopolyplex formulations for gene transfer to human colon carcinoma cells underin vitro conditions

    Article • The Journal of Gene Medicine, January 2006, Wiley

    Dr. Ernst Wagner

  346. Photochemical Internalization of Transgenes Controlled by the Heat-shock Protein 70 Promoter

    Article • Photochemistry and Photobiology, January 2006, Wiley

    Dr. Ernst Wagner

  347. EGF Receptor-Targeted Synthetic Double-Stranded RNA Eliminates Glioblastoma, Breast Cancer, and Adenocarcinoma Tumors in Mice

    Article • PLoS Medicine, December 2005, PLOS

    Dr. Ernst Wagner

  348. Apoptosis-Inducing Factor Triggered by Poly(ADP-Ribose) Polymerase and Bid Mediates Neuronal Cell Death after Oxygen-Glucose Deprivation and Focal Cerebral Ischemia

    Article • Journal of Neuroscience, November 2005, Society for Neuroscience

    MD, PhD Klas Blomgren, Dr. Ernst Wagner

  349. Cryoconserved shielded and EGF receptor targeted DNA polyplexes: cellular mechanisms

    Article • European Journal of Pharmaceutics and Biopharmaceutics, July 2005, Elsevier

    Dr. Ernst Wagner

  350. Specific Targets in Tumor Tissue for the Delivery of Therapeutic Genes

    Article • Current Medicinal Chemistry - Anti-Cancer Agents, March 2005, Bentham Science Publishers

    Dr. Ernst Wagner

  351. Toward Synthetic Viruses: Endosomal pH-Triggered Deshielding of Targeted Polyplexes Greatly Enhances Gene Transfer in vitro and in vivo

    Article • Molecular Therapy, March 2005, Elsevier

    Dr. Ernst Wagner

  352. Contribution of academic research to discovery and development of medicines: current status and future opportunities

    Article • European Journal of Pharmaceutical Sciences, February 2005, Elsevier

    Dr. Ernst Wagner

  353. Opening of Size-Selective Pores in Endosomes during Human Rhinovirus Serotype 2 In Vivo Uncoating Monitored by Single-Organelle Flow Analysis

    Article • Journal of Virology, January 2005, ASM Journals

    Dr. Ernst Wagner

  354. C- versus N-terminally linked melittin-polyethylenimine conjugates: the site of linkage strongly influences activity of DNA polyplexes

    Article • The Journal of Gene Medicine, January 2005, Wiley

    Dr. Ernst Wagner

  355. Targeting of Polyplexes: Toward Synthetic Virus Vector Systems

    Article • January 2005, Elsevier

    Dr. Ernst Wagner

  356. Functional Analysis of Genomic DNA, cDNA, and Nucleotide Sequence of the Mature C-Type Natriuretic Peptide Gene in Vascular Cells

    Article • Arteriosclerosis Thrombosis and Vascular Biology, September 2004, Wolters Kluwer Health

    Dr. Ernst Wagner

  357. Photochemically Enhanced Gene Delivery of EGF Receptor-targeted DNA Polyplexes

    Article • Journal of Drug Targeting, May 2004, Taylor & Francis

    Dr. Ernst Wagner

  358. Stabilized Nonviral Formulations for the Delivery of MCP-1 Gene into Cells of the Vasculoendothelial System

    Article • Pharmaceutical Research, April 2004, Springer Science + Business Media

    Dr. Ernst Wagner

  359. Targeted nucleic acid delivery into tumors: new avenues for cancer therapy

    Article • Biomedicine & Pharmacotherapy, April 2004, Elsevier

    Dr. Ernst Wagner

  360. In vitro andin vivo delivery of intact BAC DNA– comparison of different methods

    Article • The Journal of Gene Medicine, February 2004, Wiley

    Dr. Ernst Wagner

  361. Purification of polyethylenimine polyplexes highlights the role of free polycations in gene transfer

    Article • The Journal of Gene Medicine, January 2004, Wiley

    Dr. Ernst Wagner

  362. Strategies to Improve DNA Polyplexes for in Vivo Gene Transfer: Will “Artificial Viruses” Be the Answer?

    Article • Pharmaceutical Research, January 2004, Springer Science + Business Media

    Dr. Ernst Wagner

  363. Tumor-targeted gene therapy: strategies for the preparation of ligand–polyethylene glycol–polyethylenimine/DNA complexes

    Article • Journal of Controlled Release, August 2003, Elsevier

    Dr. Ernst Wagner

  364. Nanoparticles bearing polyethyleneglycol-coupled transferrin as gene carriers: preparation and in vitro evaluation

    Article • International Journal of Pharmaceutics, June 2003, Elsevier

    Dr. Ernst Wagner

  365. Tissue-dependent factors affect gene delivery to tumors in vivo

    Article • Gene Therapy, June 2003, Springer Science + Business Media

    Dr. Ernst Wagner

  366. Nonviral gene transfer into fetal mouse livers (a comparison between the cationic polymer PEI and naked DNA)

    Article • Gene Therapy, April 2003, Springer Science + Business Media

    Dr. Ernst Wagner

  367. Optical imaging of transferrin targeted PEI/DNA complexes in living subjects

    Article • Gene Therapy, April 2003, Springer Science + Business Media

    Dr. Ernst Wagner

  368. Article • BMC Biotechnology, January 2003, Springer Science + Business Media

    Dr. Ernst Wagner

  369. Novel Shielded Transferrin−Polyethylene Glycol−Polyethylenimine/DNA Complexes for Systemic Tumor-Targeted Gene Transfer

    Article • Bioconjugate Chemistry, January 2003, American Chemical Society (ACS)

    Dr. Ernst Wagner

  370. Reactivation of the Mitosis-Promoting Factor in Postmitotic Cardiomyocytes

    Article • Cells Tissues Organs, January 2003, Karger Publishers

    Dr. Ernst Wagner

  371. Specific systemic nonviral gene delivery to human hepatocellular carcinoma xenografts in SCID mice

    Article • Hepatology, November 2002, Wiley

    Dr. Ernst Wagner

  372. Tumor-targeted gene delivery of tumor necrosis factor-α induces tumor necrosis and tumor regression without systemic toxicity

    Article • Cancer Gene Therapy, July 2002, Springer Science + Business Media

    Dr. Ernst Wagner

  373. Novel colon cancer cell lines leading to better understanding of the diversity of respective primary cancers

    Article • Oncogene, July 2002, Springer Science + Business Media

    Dr. Ernst Wagner

  374. Targeting tumors with non-viral gene delivery systems

    Article • Drug Discovery Today, April 2002, Elsevier

    Dr. Ernst Wagner

  375. Somatic gene transfer into the lactating ovine mammary gland

    Article • The Journal of Gene Medicine, March 2002, Wiley

    Dr. Ernst Wagner

  376. Article • Somatic Cell and Molecular Genetics, January 2002, Springer Science + Business Media

    Dr. Ernst Wagner

  377. Overcoming the Nuclear Barrier: Cell Cycle Independent Nonviral Gene Transfer with Linear Polyethylenimine or Electroporation

    Article • Molecular Therapy, January 2002, Elsevier

    Dr. Ernst Wagner

  378. Tumor-targeted gene delivery: an attractive strategy to use highly active effector molecules in cancer treatment

    Article • Gene Therapy, January 2002, Springer Science + Business Media

    Dr. Ernst Wagner

  379. Article • Somatic Cell and Molecular Genetics, January 2002, Springer Science + Business Media

    Dr. Ernst Wagner

  380. Design and gene delivery activity of modified polyethylenimines

    Article • Advanced Drug Delivery Reviews, December 2001, Elsevier

    Dr. Ernst Wagner

  381. DNA/polyethylenimine transfection particles: Influence of ligands, polymer size, and PEGylation on internalization and gene expression

    Article • AAPS PharmSci, September 2001, American Association of Pharmaceutical Scientists (AAPS)

    Dr. Ernst Wagner

  382. Different Strategies for Formation of PEGylated EGF-Conjugated PEI/DNA Complexes for Targeted Gene Delivery

    Article • Bioconjugate Chemistry, July 2001, American Chemical Society (ACS)

    Dr. Ernst Wagner

  383. Functional maturation of dendritic cells by exposure to CD40L transgenic tumor cells, fibroblasts or keratinocytes

    Article • Cancer Letters, July 2001, Elsevier

    Dr. Ernst Wagner

  384. Tumor targeting with surface-shielded ligand–polycation DNA complexes

    Article • Journal of Controlled Release, May 2001, Elsevier

    Dr. Ernst Wagner

  385. Immunoadjuvant activity of interferon-γ-liposomes co-administered with influenza vaccines

    Article • Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, March 2001, Elsevier

    Dr. Ernst Wagner

  386. Different behavior of branched and linear polyethylenimine for gene deliveryin vitro andin vivo

    Article • The Journal of Gene Medicine, January 2001, Wiley

    Dr. Ernst Wagner

  387. Polyethylenimine/DNA complexes shielded by transferrin target gene expression to tumors after systemic application

    Article • Gene Therapy, January 2001, Springer Science + Business Media

    Dr. Ernst Wagner

  388. Transfection of epithelial cells is enhanced by combined treatment with mannitol and polyethyleneglycol

    Article • The Journal of Gene Medicine, January 2001, Wiley

    Dr. Ernst Wagner

  389. Xenogenization by tetanus toxoid loading into lymphoblastoid cell lines and primary human tumor cells mediated by polycations and liposomes

    Article • Cancer Letters, December 2000, Elsevier

    Dr. Ernst Wagner

  390. Interleukin-2 gene-modified allogeneic melanoma cell vaccines can induce cross-protection against syngeneic tumors in mice

    Article • Cancer Gene Therapy, June 2000, Springer Science + Business Media

    Dr. Ernst Wagner

  391. A versatile assay to study cellular uptake of gene transfer complexes by flow cytometry

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, April 2000, Elsevier

    Dr. Ernst Wagner

  392. Efficient In Vitro Transfection of Human Keratinocytes with an Adenovirus-Enhanced Receptor-Mediated System

    Article • Journal of Investigative Dermatology, April 2000, Elsevier

    Dr. Ernst Wagner

  393. Cell cycle dependence of gene transfer by lipoplex, polyplex and recombinant adenovirus

    Article • Gene Therapy, February 2000, Springer Science + Business Media

    Dr Matthew L Cotten, Dr. Ernst Wagner

  394. Article • Pharmaceutical Research, January 2000, Springer Science + Business Media

    Dr. Ernst Wagner

  395. Polymer Based Systems for Tumor-Targeted Gene Delivery

    Article • Nature Biotechnology, December 1999, Springer Science + Business Media

    Dr. Ernst Wagner

  396. Application of membrane-active peptides for nonviral gene delivery

    Article • Advanced Drug Delivery Reviews, August 1999, Elsevier

    Dr. Ernst Wagner

  397. Membrane destabilization for improved cystolic delivery

    Article • Advanced Drug Delivery Reviews, August 1999, Elsevier

    Dr. Ernst Wagner

  398. Mannose Polyethylenimine Conjugates for Targeted DNA Delivery into Dendritic Cells

    Article • Journal of Biological Chemistry, July 1999, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr. Ernst Wagner

  399. Differential behaviour of lipid based and polycation based gene transfer systems in transfecting primary human fibroblasts: a potential role of polylysine in nuclear transport

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, June 1999, Elsevier

    Dr. Ernst Wagner

  400. Liposomes as cytokine-supplement in tumor cell-based vaccines

    Article • International Journal of Pharmaceutics, June 1999, Elsevier

    Dr. Ernst Wagner

  401. Immunotherapy of Metastatic Malignant Melanoma by a Vaccine Consisting of Autologous Interleukin 2-Transfected Cancer Cells: Outcome of a Phase I Study

    Article • Human Gene Therapy, April 1999, Mary Ann Liebert Inc

    Dr. Ernst Wagner

  402. PEGylated DNA/transferrin–PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery

    Article • Gene Therapy, April 1999, Springer Science + Business Media

    Dr. Ernst Wagner

  403. Efficient Gene Delivery into Human Dendritic Cells by Adenovirus Polyethylenimine and Mannose Polyethylenimine Transfection

    Article • Human Gene Therapy, March 1999, Mary Ann Liebert Inc

    Dr Matthew L Cotten, Dr. Ernst Wagner

  404. Polycation-based DNA complexes for tumor-targeted gene deliveryin vivo

    Article • The Journal of Gene Medicine, March 1999, Wiley

    Dr. Ernst Wagner

  405. Development of Transferrin-Polycation/DNA Based Vectors for Gene Delivery to Melanoma Cells

    Article • Journal of Drug Targeting, January 1999, Taylor & Francis

    Dr. Ernst Wagner

  406. Ligand—Polycation Conjugates for Receptor-Targeted Gene Transfer

    Article • January 1999, Elsevier

    Dr. Ernst Wagner

  407. Application of membrane-active peptides for drug and gene delivery across cellular membranes

    Article • Advanced Drug Delivery Reviews, October 1998, Elsevier

    Dr. Ernst Wagner

  408. The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells

    Article • Gene Therapy, October 1998, Springer Science + Business Media

    Dr. Ernst Wagner

  409. Influence of the DNA complexation medium on the transfection efficiency of lipospermine/DNA particles

    Article • Gene Therapy, June 1998, Springer Science + Business Media

    Dr. Ernst Wagner

  410. An RGD–Oligolysine Peptide: A Prototype Construct for Integrin-Mediated Gene Delivery

    Article • Human Gene Therapy, May 1998, Mary Ann Liebert Inc

    Dr. Ernst Wagner

  411. Effects of membrane-active agents in gene delivery

    Article • Journal of Controlled Release, April 1998, Elsevier

    Dr. Ernst Wagner

  412. Polylysine-based transfection systems utilizing receptor-mediated delivery

    Article • Advanced Drug Delivery Reviews, March 1998, Elsevier

    Dr. Ernst Wagner

  413. Increase of proliferation rate and enhancement of antitumor cytotoxicity of expanded human CD3+CD56+ immunologic effector cells by receptor-mediated transfection with the interleukin-7 gene

    Article • Gene Therapy, January 1998, Springer Science + Business Media

    Dr. Ernst Wagner

  414. Gene-Modified Dendritic Cells by Receptor-Mediated Transfection

    Article • January 1998, Springer Science + Business Media

    Dr. Ernst Wagner

  415. Stabilization of gene delivery systems by freeze-drying

    Article • International Journal of Pharmaceutics, November 1997, Elsevier

    Dr. Ernst Wagner

  416. Coupling of cell-binding ligands to polyethylenimine for targeted gene delivery

    Article • Gene Therapy, May 1997, Springer Science + Business Media

    Dr. Ernst Wagner

  417. Phase I study to the immunotherapy of metastatic malignant melanoma by a cancer vaccine consisting of autologous cancer cells transfected with the human IL-2 gene

    Article • Journal of Molecular Medicine, April 1997, Springer Science + Business Media

    Dr. Ernst Wagner

  418. Glycerol and Polylysine Synergize in Their Ability to Rupture Vesicular Membranes: A Mechanism for Increased Transferrin–Polylysine-Mediated Gene Transfer1

    Article • Experimental Cell Research, April 1997, Elsevier

    Dr. Ernst Wagner

  419. Lymphocyte apoptosis: induction by gene transfer techniques

    Article • Gene Therapy, April 1997, Springer Science + Business Media

    Dr. Ernst Wagner

  420. Nomenclature for Synthetic Gene Delivery Systems

    Article • Human Gene Therapy, March 1997, Mary Ann Liebert Inc

    Dr. Ernst Wagner

  421. Influence of Membrane-Active Peptides on Lipospermine/DNA Complex Mediated Gene Transfer

    Article • Bioconjugate Chemistry, March 1997, American Chemical Society (ACS)

    Dr. Ernst Wagner

  422. The cdc2Ms Kinase Is Differently Regulated in the Cytoplasm and in the Nucleus

    Article • PLANT PHYSIOLOGY, March 1997, American Society of Plant Biologists (ASPB)

    Dr. Ernst Wagner

  423. In vitro targeting and specific transfection of human neuroblastoma cells by chCE7 antibody-mediated gene transfer

    Article • Gene Therapy, February 1997, Springer Science + Business Media

    Dr. Ernst Wagner

  424. Functional Re-expression of Laminin-5 in Laminin-γ2-deficient Human Keratinocytes Modifies Cell Morphology, Motility, and Adhesion

    Article • Journal of Biological Chemistry, August 1996, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr. Ernst Wagner

  425. Activation of the Complement System by Synthetic DNA Complexes: A Potential Barrier for Intravenous Gene Delivery

    Article • Human Gene Therapy, August 1996, Mary Ann Liebert Inc

    Dr. Ernst Wagner

  426. Extrachromosomal recombination occurs efficiently in cells defective in various DNA repair systems

    Article • Nucleic Acids Research, June 1996, Oxford University Press (OUP)

    Dr. Ernst Wagner

  427. Glycerol Enhancement of Ligand-Polylysine/DNA Transfection

    Article • BioTechniques, May 1996, Future Science

    Dr. Ernst Wagner

  428. Developmental and Cell Cycle Regulation of Alfalfa nucMs1, a Plant Homolog of the Yeast Nsr1 and Mammalian Nucleolin

    Article • The Plant Cell, March 1996, JSTOR

    Dr. Ernst Wagner

  429. Phase I Study to the Immunotherapy of Metastatic Malignant Melanoma by a Cancer Vaccine Consisting of Autologous Cancer Cells Transfected with the Human IL-2 Gene. University of Vienna, Austria

    Article • Human Gene Therapy, March 1996, Mary Ann Liebert Inc

    Dr. Ernst Wagner

  430. Developmental and cell cycle regulation of alfalfa nucMs1, a plant homolog of the yeast Nsr1 and mammalian nucleolin.

    Article • The Plant Cell, March 1996, American Society of Plant Biologists (ASPB)

    Dr. Ernst Wagner

  431. Virus-mediated release of endosomal content in vitro: different behavior of adenovirus and rhinovirus serotype 2

    Article • Journal of Cell Biology, October 1995, Rockefeller University Press

    Dr. Ernst Wagner

  432. Receptor-Mediated Gene Transfer into Human T Lymphocytes via Binding of DNA/CD3 Antibody Particles to the CD3 T Cell Receptor Complex

    Article • Human Gene Therapy, June 1995, Mary Ann Liebert Inc

    Dr. Ernst Wagner

  433. Regulation of the Tissue Factor Promoter in Endothelial Cells

    Article • Journal of Biological Chemistry, February 1995, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr. Ernst Wagner

  434. Rhinovirus-mediated endosomal release of transfection complexes.

    Article • Journal of Virology, January 1995, ASM Journals

    Dr. Ernst Wagner

  435. Psoralen Treatment of Adenovirus Particles Eliminates Virus Replication and Transcription While Maintaining the Endosomolytic Activity of the Virus Capsid

    Article • Virology, November 1994, Elsevier

    Dr. Ernst Wagner

  436. High-Level Expression of Various Apolipoprotein (a) Isoforms by "Transferrinfection": The Role of Kringle IV Sequences in the Extracellular Association with Low-Density Lipoprotein

    Article • Biochemistry, October 1994, American Chemical Society (ACS)

    Dr. Ernst Wagner

  437. Synthesis and anti-HIV activity of thiocholesteryl-coupled phosphodiester antisense oligonucleotides incorporated into immunoliposomes

    Article • Antiviral Research, September 1994, Elsevier

    Dr. Ernst Wagner

  438. In vivo production of human factor VII in mice after intrasplenic implantation of primary fibroblasts transfected by receptor-mediated, adenovirus-augmented gene delivery.

    Article • Proceedings of the National Academy of Sciences, May 1994, Proceedings of the National Academy of Sciences

    Dr Matthew L Cotten, Dr. Ernst Wagner

  439. Chirale Lactole, XI. Eine Methode zur Bestimmung der Absolutkonfiguration chiraler Alkanole

    Article • European Journal of Inorganic Chemistry, May 1994, Wiley

    Dr. Ernst Wagner

  440. Delivery of drugs, proteins and genes into cells using transferrin as a ligand for receptor-mediated endocytosis

    Article • Advanced Drug Delivery Reviews, April 1994, Elsevier

    Dr. Ernst Wagner

  441. Efficient Foreign Gene Expression in Epstein-Barr Virus-Transformed Human B-Cells

    Article • Virology, February 1994, Elsevier

    Dr Matthew L Cotten, Dr. Ernst Wagner

  442. Carbohydrate receptor-mediated gene transfer to human T leukaemic cells

    Article • Glycobiology, January 1994, Oxford University Press (OUP)

    Dr. Ernst Wagner

  443. Gene Therapy for B-cell Lymphoma in a SCID Mouse Model using an Immunoglobulin-Regulated Diphtheria Toxin Gene Delivered by a Novel Adenovirus-Polylysine Conjugate

    Article • Cancer Biotherapy, January 1994, Mary Ann Liebert Inc

    Dr. Ernst Wagner

  444. Somatic gene therapy for cancer: the utility of transferrinfection in generating ‘tumor vaccines’

    Article • Gene, December 1993, Elsevier

    Dr Matthew L Cotten, Dr. Ernst Wagner

  445. Non-viral approaches to gene therapy

    Article • Current Opinion in Biotechnology, December 1993, Elsevier

    Dr. Ernst Wagner

  446. Receptor-mediated Gene Transfer to Airway Epithelial Cells in Primary Culture

    Article • American Journal of Respiratory Cell and Molecular Biology, October 1993, American Thoracic Society

    Dr. Ernst Wagner

  447. Direct In Vivo Gene Transfer to Airway Epithelium Employing Adenovirus–Polylysine–DNA Complexes

    Article • Human Gene Therapy, February 1993, Mary Ann Liebert Inc

    Dr Matthew L Cotten, Dr. Ernst Wagner

  448. [42] Receptor-mediated transport of DNA into eukaryotic cells

    Article • January 1993, Elsevier

    Dr Matthew L Cotten, Dr. Ernst Wagner

  449. Chicken adenovirus (CELO virus) particles augment receptor-mediated DNA delivery to mammalian cells and yield exceptional levels of stable transformants.

    Article • Journal of Virology, January 1993, ASM Journals

    Dr. Ernst Wagner

  450. Gene transfer into hepatocytes using asialoglycoprotein receptor mediated endocytosis of DNA complexed with an artificial tetra-antennary galactose ligand

    Article • Bioconjugate Chemistry, November 1992, American Chemical Society (ACS)

    Dr. Ernst Wagner

  451. Transferrinfection: A Highly Efficient Way to Express Gene Constructs in Eukaryotic Cells

    Article • Annals of the New York Academy of Sciences, October 1992, Wiley

    Dr. Ernst Wagner

  452. Influenza virus hemagglutinin HA-2 N-terminal fusogenic peptides augment gene transfer by transferrin-polylysine-DNA complexes: toward a synthetic virus-like gene-transfer vehicle.

    Article • Proceedings of the National Academy of Sciences, September 1992, Proceedings of the National Academy of Sciences

    Dr Matthew L Cotten, Dr. Ernst Wagner

  453. High-efficiency receptor-mediated delivery of small and large (48 kilobase gene constructs using the endosome-disruption activity of defective or chemically inactivated adenovirus particles.

    Article • Proceedings of the National Academy of Sciences, July 1992, Proceedings of the National Academy of Sciences

    Dr Matthew L Cotten, Dr. Ernst Wagner

  454. Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor-mediated gene delivery and expression of transfected genes.

    Article • Proceedings of the National Academy of Sciences, July 1992, Proceedings of the National Academy of Sciences

    Dr Matthew L Cotten, Dr. Ernst Wagner

  455. High-Efficiency Gene Transfer Mediated by Adenovirus Coupled to DNA–Polylysine Complexes

    Article • Human Gene Therapy, April 1992, Mary Ann Liebert Inc

    Dr Matthew L Cotten, Dr. Ernst Wagner

  456. Gene Transfer to Respiratory Epithelial Cells via the Receptor-mediated Endocytosis Pathway

    Article • American Journal of Respiratory Cell and Molecular Biology, March 1992, American Thoracic Society

    Dr. Ernst Wagner

  457. Effective incorporation of 2'-O-methyl-oligoribonuclectides into liposomes and enhanced cell association through modification with thiocholesterol

    Article • Nucleic Acids Research, January 1992, Oxford University Press (OUP)

    Dr. Ernst Wagner

  458. Adenovirus enhancement of transferrin-polylysine-mediated gene delivery.

    Article • Proceedings of the National Academy of Sciences, October 1991, Proceedings of the National Academy of Sciences

    Dr Matthew L Cotten, Dr. Ernst Wagner

  459. DNA-binding transferrin conjugates as functional gene-delivery agents: synthesis by linkage of polylysine or ethidium homodimer to the transferrin carbohydrate moiety

    Article • Bioconjugate Chemistry, July 1991, American Chemical Society (ACS)

    Dr. Ernst Wagner

  460. 2'-O-methyl, 2'-O-ethyl oligoribonucleotides and phosphorothioate oligodeoxyribonucleotides as inhibitors of the in vitro U7 snRNP-dependent mRNA processing event

    Article • Nucleic Acids Research, May 1991, Oxford University Press (OUP)

    Dr. Ernst Wagner

  461. Transferrin-polycation-DNA complexes: the effect of polycations on the structure of the complex and DNA delivery to cells.

    Article • Proceedings of the National Academy of Sciences, May 1991, Proceedings of the National Academy of Sciences

    Dr. Ernst Wagner

  462. Pheromone, 3.Mitt.: Eine einfache Methode zur Steuerung der Reduktion von ?-Alkoxy-carbonylverbindungen

    Article • Monatshefte für Chemie - Chemical Monthly, April 1991, Springer Science + Business Media

    Dr. Ernst Wagner

  463. A simple procedure for the preparation of protected 2′-O-methyl or 2′-O-ethyl ribonucleoside-3′-O-phosphoramidites

    Article • Nucleic Acids Research, January 1991, Oxford University Press (OUP)

    Dr Matthew L Cotten, Dr. Ernst Wagner

  464. Chemie von a-Aminonitrilen. Aldomerisierung von Glycolaldehyd-phosphat zu racemischen Hexose-2,4,6-triphosphaten und (in Gegenwart von Formaldehyd) racemischen Pentose-2,4-diphosphaten: rac-Allose-2,4,6-triphosphat und rac-Ribose-2,4-diphosphat sind die R

    Article • Helvetica Chimica Acta, August 1990, Wiley

    Dr. Ernst Wagner

  465. Chemie von α-Aminonitrilen. Aziridin-2-carbonitril, ein Vorläufer von rca-O3-Phosphoserinnitril und Glycolaldehyd-phosphat

    Article • Helvetica Chimica Acta, August 1990, Wiley

    Dr. Ernst Wagner

  466. Transferrin-polycation-mediated introduction of DNA into human leukemic cells: stimulation by agents that affect the survival of transfected DNA or modulate transferrin receptor levels.

    Article • Proceedings of the National Academy of Sciences, June 1990, Proceedings of the National Academy of Sciences

    Dr. Ernst Wagner

  467. Receptor-mediated endocytosis of transferrin-polycation conjugates: an efficient way to introduce DNA into hematopoietic cells.

    Article • Proceedings of the National Academy of Sciences, May 1990, Proceedings of the National Academy of Sciences

    Dr. Ernst Wagner

  468. Transferrin-polycation conjugates as carriers for DNA uptake into cells.

    Article • Proceedings of the National Academy of Sciences, May 1990, Proceedings of the National Academy of Sciences

    Dr. Ernst Wagner

  469. Ein einfaches Verfahren zur Herstellung anellierter Thiophene

    Article • Monatshefte für Chemie - Chemical Monthly, May 1986, Springer Science + Business Media

    Dr. Ernst Wagner

  470. Chirale Lactole, VI. Eine Methode zur Bestimmung der Absolutkonfiguration chiraler α-hydroxysubstituierter Nitrile, Alkine und Aldehyde

    Article • European Journal of Inorganic Chemistry, February 1986, Wiley

    Dr. Ernst Wagner

  471. Kohlenhydrat-Modelle, I. Kinetische und thermodynamische Effekte bei Acetalisierungsreaktionen enantiomerenreiner Thiolactole

    Article • European Journal of Inorganic Chemistry, August 1985, Wiley

    Dr. Ernst Wagner

  472. Chirale Lactole, IV. Selektivitäten bei Acetalisierungsreaktionen enantiomerenreiner Lactole am Beispiel von Octahydro-8,9,9-trimethyl-5,8-methano-2H-1-benzopyran-2-ol

    Article • European Journal of Inorganic Chemistry, May 1985, Wiley

    Dr. Ernst Wagner

  473. Gene Delivery Using Polymer Therapeutics

    Article • Springer Science + Business Media

    Dr. Ernst Wagner

  474. Nonviral Vector Systems for Cancer Gene Therapy

    Article • Springer Science + Business Media

    Dr. Ernst Wagner

  475. Optimizing Polyplexes into Synthetic Viruses for Tumor-Targeted Gene Therapy

    Article • Springer Science + Business Media

    Dr. Ernst Wagner

  476. In Vitro Gene Transfection with Surface-Modified Gelatin Nanoparticles

    Article • Institute of Electrical & Electronics Engineers (IEEE)

    Dr. Ernst Wagner

  477. Article • PLOS

    Dr. Ernst Wagner