What is it about?
Collagen has a pivotal role in cancer progression, metastasis, and therapeutic response; accordingly, it might represent a target for cancer treatment. In this manuscript the authors provide an overview of the current advances and challenges of the main approaches aiming at tumor collagen normalization for cancer therapy. These strategies include targeted anticancer drug delivery, promotion of collagen degradation, modulation of collagen structure and biosynthesis, and targeting of cancer-associated fibroblasts.
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This page is a summary of: Strategies for Efficient Targeting of Tumor Collagen for Cancer Therapy, Cancers, September 2022, MDPI AG,
DOI: 10.3390/cancers14194706.
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Resources
Open access version
Strategies for Efficient Targeting of Tumor Collagen for Cancer Therapy
Cancers Special Issue
Tumor Microenvironment Heterogeneity in Cancer Progression: Challenge or Opportunity
Scholarly Community Encyclopedia
Therapeutic Targeting of Tumor Collagen
Therapeutic targeting of tumor collagen
Schematic representation of different strategies of therapeutic targeting of tumor collagen.
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