What is it about?

Computerized physician order entry (CPOE) systems are incorporated into clinical decision support systems (CDSSs) to reduce medication errors and improve patient safety. Automatic alerts generated from CDSSs can directly assist physicians in making useful clinical decisions and can help shape prescribing behavior. Multiple studies reported that approximately 90%-96% of alerts are overridden by physicians, which raises questions about the effectiveness of CDSSs. There is intense interest in developing sophisticated methods to combat alert fatigue, but there is no consensus on the optimal approaches so far.Our objective was to develop machine learning prediction models to predict physicians' responses in order to reduce alert fatigue from disease medication-related CDSSs.

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Why is it important?

We hypothesized that machine learning models could predict physician responses, which would ultimately directly assist in developing a sophisticated CDSS for reducing alert fatigue. Therefore, the primary objective of this study was to develop and validate machine learning models to reduce alert fatigue by predicting physician responses. This study may provide perspective on the perceived usefulness of CDSS alerts in patient care and insights into how to design better alert systems in real-world clinical settings. It can contribute to minimizing the number of alerts in the user interface, ensuring the appropriate prescription, and reducing the severity of unintended consequences.

Perspectives

In this study, ANN showed substantially better performance in predicting individual physician responses to an alert from a disease medication–related CDSS, as compared to the other models. To our knowledge, this is the first study to use machine learning models to predict physician responses to alerts; furthermore, it can help to develop sophisticated CDSSs in real-world clinical settings.

Md.Mohaimenul Islam
Taipei Medical University

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This page is a summary of: Machine Learning Approach to Reduce Alert Fatigue Using a Disease Medication–Related Clinical Decision Support System: Model Development and Validation, JMIR Medical Informatics, November 2020, JMIR Publications Inc.,
DOI: 10.2196/19489.
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