What is it about?
Exploring the binding pocket of target receptor assists researchers to tailor the ligands' backbones with functionalities that better fit the active site. Assigning the fingerprint of receptor's activator or inhibitor guides researchers to incorporate attachments on proper position.
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Why is it important?
Dip into medicinal chemistry tool employing drug design tactics and molecular biology procedures to approve the proposed aims.
Perspectives
Narrating the story and adventure of each article has its own flavor and secret touch. Nothing goes easily as I believe that the climax needs sacrifice.
Prof. Dima A. Sabbah
Al-Zaytoonah Private University of Jordan
Read the Original
This page is a summary of: Molecular Docking Studies of Novel Thiosemicarbazone-based Indoles as Potential PI3Kα Inhibitors, Letters in Drug Design & Discovery, October 2017, Bentham Science Publishers,
DOI: 10.2174/1570180814666170619112647.
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