Nutrient withdrawal rescues growth factor-deprived cells from mTOR-dependent damage

What is it about?

Authors report a novel mechanism for cell survival regulation by nutrients. In particular, unbalanced mTOR activity in the absence of adequate growth factor supply, may represent a general mechanism of cell death by excess nutrients. This may be relevant in the study of tissue hyperglycemic damage, in body senescence and cancer therapy, prospectively suggesting a possible pharmacological target for novel preventive and therapeutic strategies.

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Photo by Markus Winkler on Unsplash

Photo by Markus Winkler on Unsplash