What is it about?
Manganese (II) complexes of oxalic dihydrazones {N,N'-bis[2-hydroxynaphthylidene]amino]oxamide (BHO) and N,N'-bis[2-methoxybenzylidene]amino]oxamide (BMO)} have been synthesized. In view of the data acquired from the elemental analyses (CHNM), spectral (IR, mass, 1H-NMR, UV-Vis., ESR), thermal and magnetic measurements, the structures of ligands and their complexes have been set up. The surface morphology of the desired complexes was examined by SEM. The manganese complexes are proposed to have octahedral stereochemistry. The free ligands and their manganese (II) complexes were assessed for their antibacterial and antileukemia activities. The obtained information uncovered that the proliferation hindrance for the free ligands was enhanced upon coordination with the manganese (II) ions.
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Why is it important?
The synthesized compounds have applications in pharmaceutical. They can be used as antibacterials - anti tumor.
Perspectives
Writing this article was a great pleasure and ultimately to a greater involvement in dangerous disease research.
Prof Ayman H Ahmed
Al-Jouf University
Read the Original
This page is a summary of: N,N′-Bis[2-hydroxynaphthylidene]/[2-methoxybenzylidene]amino]oxamides and their divalent manganese complexes: Isolation, spectral characterization, morphology, antibacterial and cytotoxicity against leukemia cells, Open Chemistry, May 2020, De Gruyter,
DOI: 10.1515/chem-2020-0044.
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