What is it about?

TSH is subject to feedback regulation by thyroid hormones.

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Why is it important?

This study examines the differential contributions of FT4 and FT3 in the feedback control of pituitary TSH.

Perspectives

Circulating FT3 levels impact on pituitary TSH, both directly and by interaction with FT4, suggesting cascade control of the regulation. Practical implications for LT4 treatment are discussed.

Professor Rudolf Hoermann

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This page is a summary of: Dual control of pituitary thyroid stimulating hormone secretion by thyroxine and triiodothyronine in athyreotic patients, Therapeutic Advances in Endocrinology and Metabolism, June 2017, SAGE Publications,
DOI: 10.1177/2042018817716401.
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