What is it about?
Adipose tissue–derived stromal/stem cells are gaining increasing consideration in tissue repair therapeutic application. Authos show that the therapeutic potential of diabetic stromal vascular fraction cells administered to wounds of diabetic mice was blunted as compared with cells isolated from nondiabetic mice. These data indicate that diabetes alters stromal cells intrinsic properties and impairs their function, thus affecting therapeutic potential in the autologous treatment for diabetic ulcers.
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This page is a summary of: Diabetes impairs adipose tissue–derived stem cell function and efficiency in promoting wound healing, Wound Repair and Regeneration, April 2013, Wiley,
DOI: 10.1111/wrr.12051.
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Diabetes impairs adipose tissue-derived stem cell function and efficiency in promoting wound healing: Impaired prohealing function of diabetic ASCs
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Faculty1000 Recommendation
Gimble J and Strong A: F1000Prime Recommendation of [Cianfarani F et al., Wound Repair Regen 2013 21(4):545-553]. In F1000Prime, 23 Jul 2013; 10.3410/f.718023676.793479448
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