Scientists find an easy way to produce novel macrocyclic molecules containing iodine

What is it about?

Macrocycles are chemical compounds that have rather large molecular rings. They form the building blocks of many complex molecular structures and play an important role in chemistry. In this study, the authors explored if iodine ions forming bonds with nitrogen atoms may be used as links in macrocyclic rings. By using a simple reaction, they managed to produce three new macrocycles. Through a series of experiments, the researchers shed light on the structure and electronic arrangement of these molecules. The macrocycles produced were symmetrical and stable, which is important in practical applications. Besides, these molecules could firmly bind a guest molecule inside their rings. This is indeed a remarkable property.

Featured Image

Photo by Sharon McCutcheon on Unsplash

Photo by Sharon McCutcheon on Unsplash

Why is it important?

Macrocycles appear naturally in the world and have important biological roles. Specially designed macrocycles are used to produce important medicines. For instance, several antibiotics and antifungal compounds are based on macrocycles. Moreover, macrocycles have promising uses in industrial applications, such as gas capture and catalysis. In this study, the researchers showed how a straightforward chemical reaction used to produce simpler molecules can also be used to create macrocycles. This expands the scope of macrocycle chemistry further and serves as a basis for future studies in this field. KEY TAKEAWAY: This study paves the way for further research on novel macrocycles containing iodine.