What is it about?
Here we present an alternating current (ac) induced electric field-based biochip platform, which has an open-top sub-mm square chamber enclosed by four sidewall electrodes and two bottom electrodes, to achieve rotation about the two axes, thus 3D cell rotation.
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Photo by Adrian Dascal on Unsplash
Why is it important?
The precise rotation of suspended cells is one of the many fundamental manipulations used in a wide range of biotechnological applications such as cell injection and enucleation in nuclear transfer (NT) cloning. Noticeably scarce among the existing rotation techniques is the three-dimensional (3D) rotation of cells on a single chip.
Perspectives
This simple, transparent, cheap-to-manufacture, and open-top platform allows additional functional modules to be integrated to become a more powerful cell manipulation system.
Professor Wenhui Wang
Tsinghua University
Read the Original
This page is a summary of: AC electric field induced dipole-based on-chip 3D cell rotation, Lab on a Chip, January 2014, Royal Society of Chemistry,
DOI: 10.1039/c4lc00312h.
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