What is it about?

The increase of solubility of phenolic compouds in organic solvent via complexation with lipids

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Why is it important?

This finding is useful to develop an ointment-based dosage form of phenolic compunds.

Perspectives

This phenomena is based on 1:1 and 1:2 complexation of phenolic coumpunds with lipids.

Dr Katsumi Iga
Doshisha Joshi Daigaku

Read the Original

This page is a summary of: Solubility Behavior of Phenolic Compounds in Hexane—ethyl Acetate, Hexane—ethyl Myristate, and Hexane-Ethyl Pivalate Cosolvent Systems, Journal of Pharmaceutical Sciences, November 1981, Elsevier,
DOI: 10.1002/jps.2600701111.
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