What is it about?
Cellular aging is responsible for epithelial thinning and relief from this mediates hyperplastic epithelium and malignant transformation in oral submucous fibrosis.
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Why is it important?
This article gives a novel mechanism for oral submucous fibrosis development through the aging of epithelial and connective tissue compartments. Inhibition of this process has the potential to restore epithelial homeostasis.
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This page is a summary of: Emerging role of cellular senescence in the pathogenesis of oral submucous fibrosis and its malignant transformation, Head & Neck, July 2021, Wiley,
DOI: 10.1002/hed.26805.
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