What is it about?
One drug for one target for one disease is slowly superseded by a multi-target, network- and mechanism based approach. cGMP signalling and its targets seems to be the ideal proof-of-concept.
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Why is it important?
A pilot for major innovations to drug discovery and therapy.
Perspectives
Read the Original
This page is a summary of: Clinical relevance of cyclic GMP modulators: A translational success story of network pharmacology, Clinical Pharmacology & Therapeutics, February 2016, Wiley,
DOI: 10.1002/cpt.336.
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