What is it about?

Site-directed mutagenesis shows that salt bridges in the dimer interface of proline dehydrogenase from Thermus thermophilus improve the enzyme thermal stability.

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Why is it important?

This work learns us more about the molecular determinants of enzyme stability.

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This page is a summary of: Dimerization of Proline Dehydrogenase from Thermus thermophilus Is Crucial for Its Thermostability, Biotechnology Journal, April 2019, Wiley,
DOI: 10.1002/biot.201800540.
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