What is it about?
Cloning of full-length light and heavy immunoglobulin A chains, as well as the variable regions of these chains into the genomic sequence of a plant virus, for the high-level expression of reconstituted, active antibody
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Why is it important?
Because the production of specific highly functional antibodies could be scaled up to high-level production using plants and the appropriately constructed virus vectors
Perspectives
Plants can host the production of high-level amounts of recombinant therapeutic proteins, including antibodies, with the proper eukaryotic decoration
Dr Josefa M. Alamillo
University of Cordoba
Read the Original
This page is a summary of: Use of virus vectors for the expression in plants of active full-length and single chain anti-coronavirus antibodies, Biotechnology Journal, October 2006, Wiley,
DOI: 10.1002/biot.200600143.
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