What is it about?
A novel approach to image formation in OCT, synthetic OCT, is reported. The approach is based on reconstruction of the axial spatial harmonics of the object’s structure within detected bandwidth. The synOCT permits to access the sub-wavelength structure at areas smaller, than resolution limit of the imaging system, with nano-sensitivity to structural changes, and opens new possibility for super-resolution imaging.
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Why is it important?
The proposed approach extends abilities of the OCT to detect and visualize the internal sub-wavelength structures with nano-sensitivity to structural alterations. Namely, the demonstrated quantitative estimation of the sub-micrometer structure within biological samples and human skin in vivo with nano-sensitivity to structural changes and improvement in resolution shows the potential of the proposed approach for broad applications in medicine, biology, and industry.
Perspectives
The abilities of the proposed approach to probe sub-micron structure within regions with sizes smaller than resolution limit of the imaging system provides potential for super-resolution imaging. Beside that, the numerical extension of the reconstructed spatial harmonics of the object could extend the imaged depth range beyond the fundamental limit.
Dr Sergey Alexandrov
National University of Ireland - Galway
Read the Original
This page is a summary of: Synthetic Fourier Domain Optical Coherence Tomography, Advanced Photonics Research, January 2024, Wiley,
DOI: 10.1002/adpr.202300260.
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