All Stories

  1. Differential sensitivity of acute myeloid leukemia cells to daunorubicin depends on P2X7A versus P2X7B receptor expression

    Article • Cell Death and Disease, October 2020, Springer Science + Business Media

    Professor Elena Adinolfi

  2. P2X7 in Cancer: From Molecular Mechanisms to Therapeutics

    Article • Frontiers in Pharmacology, June 2020, Frontiers

    Professor Elena Adinolfi

  3. The P2X7 Receptor 489C>T Gain of Function Polymorphism Favors HHV-6A Infection and Associates With Female Idiopathic Infertility

    Article • Frontiers in Pharmacology, February 2020, Frontiers

    Professor Elena Adinolfi

  4. Detection of Extracellular ATP in the Tumor Microenvironment, Using the pmeLUC Biosensor

    Article • October 2019, Springer Science + Business Media

    Professor Elena Adinolfi

  5. Role of the P2X7 receptor in tumor-associated inflammation

    Article • Current Opinion in Pharmacology, August 2019, Elsevier

    Professor Elena Adinolfi

  6. Amyloid β-dependent mitochondrial toxicity in mouse microglia requires P2X7 receptor expression and is prevented by nimodipine

    Article • Scientific Reports, April 2019, Springer Science + Business Media

    Professor Elena Adinolfi

  7. Involvement of P2X7 Receptors in the Osteogenic Differentiation of Mesenchymal Stromal/Stem Cells Derived from Human Subcutaneous Adipose Tissue

    Article • Stem Cell Reviews and Reports, April 2019, Springer Science + Business Media

    Professor Elena Adinolfi

  8. The P2X7 receptor modulates immune cells infiltration, ectonucleotidases expression and extracellular ATP levels in the tumor microenvironment

    Article • Oncogene, January 2019, Springer Science + Business Media

    Professor Elena Adinolfi

  9. Structure, function and techniques of investigation of the P2X7 receptor (P2X7R) in mammalian cells

    Article • January 2019, Elsevier

    Professor Elena Adinolfi

  10. Extracellular ATP and P2 purinergic signalling in the tumour microenvironment

    Article • Nature Reviews Cancer, July 2018, Springer Science + Business Media

    Professor Elena Adinolfi

  11. Emerging Roles of Purinergic Signaling in Diabetes

    Article • Medicinal Chemistry, July 2018, Bentham Science Publishers

    Professor Diego Dal Ben, Professor Elena Adinolfi

  12. Kinin and Purine Signaling Contributes to Neuroblastoma Metastasis

    Article • Frontiers in Pharmacology, May 2018, Frontiers

    Professor Elena Adinolfi

  13. The P2X7 receptor: A main player in inflammation

    Article • Biochemical Pharmacology, May 2018, Elsevier

    Professor Elena Adinolfi

  14. ATP Release from Chemotherapy-Treated Dying Leukemia Cells Elicits an Immune Suppressive Effect by Increasing Regulatory T Cells and Tolerogenic Dendritic Cells

    Article • Frontiers in Immunology, December 2017, Frontiers

    Professor Elena Adinolfi

  15. P2X7 receptor orchestrates multiple signalling pathways triggering inflammation, autophagy and metabolic/trophic responses.

    Article • Current Medicinal Chemistry, March 2017, Bentham Science Publishers

    Professor Elena Adinolfi

  16. Extracellular ATP induces apoptosis through P2X7R activation in acute myeloid leukemia cells but not in normal hematopoietic stem cells

    Article • Oncotarget, December 2016, Impact Journals, LLC

    Professor Elena Adinolfi

  17. P2 receptors in cancer progression and metastatic spreading

    Article • Current Opinion in Pharmacology, August 2016, Elsevier

    Professor Elena Adinolfi

  18. Extracellular purines, purinergic receptors and tumor growth

    Article • Oncogene, June 2016, Nature

    Professor Elena Adinolfi

  19. new insights on the therapeutic potential of P2X7 antagonists in human pathology

    Article • January 2016, Elsevier

    Professor Elena Adinolfi

  20. Emerging Roles of P2X Receptors in Cancer

    Article • Current Medicinal Chemistry, February 2015, Bentham Science Publishers

    Professor Elena Adinolfi

  21. Editorial (Thematic Issue: Purinergic P2X Receptors: Physiological and Pathological Roles and Potential as Therapeutic Targets)

    Article • Current Medicinal Chemistry, February 2015, Bentham Science Publishers

    Professor Diego Dal Ben, Professor Elena Adinolfi

  22. The P2X7 receptor is a key modulator of the PI3K/GSK3β/VEGF signaling network: evidence in experimental neuroblastoma

    Article • Oncogene, January 2015, Nature

    Professor Elena Adinolfi

  23. Accelerated Tumor Progression in Mice Lacking the ATP Receptor P2X7

    Article • Cancer Research, December 2014, American Association for Cancer Research (AACR)

    Professor Paolo Pinton, Professor Elena Adinolfi

  24. Trophic Activity of Human P2X7 Receptor Isoforms A and B in Osteosarcoma

    Article • PLoS ONE, September 2014, PLOS

    Professor Elena Adinolfi

  25. P2X receptors: New players in cancer pain

    Article • World Journal of Biological Chemistry, January 2014, Baishideng Publishing Group Co., Limited (formerly WJG Press)

    Professor Elena Adinolfi

  26. New intriguing roles of ATP and its receptors in promoting tumor metastasis

    Article • Purinergic Signalling, November 2013, Springer Science + Business Media

    Professor Elena Adinolfi

  27. Purinergic Signaling in Bone

    Article • Journal of Osteoporosis, January 2013, Hindawi Publishing Corporation

    Professor Elena Adinolfi, Peter Schwarz

  28. The P2X7 receptor is a key modulator of aerobic glycolysis

    Article • Cell Death and Disease, August 2012, Nature

    Professor Elena Adinolfi

  29. First in vivo demonstration that P2X7 receptor is an oncogene

    Article • Cancer Research, April 2012, American Association for Cancer Research (AACR)

    Professor Elena Adinolfi

  30. role of P2X7 receptor in bone cancer and bone metastasis

    Article • Journal of Osteoporosis, January 2012, Hindawi Publishing Corporation

    Professor Elena Adinolfi

  31. The dominant-negative von Willebrand factor gene deletion p.P1127_C1948delinsR: molecular mechanism and modulation

    Article • Blood, June 2010, American Society of Hematology

    Professor Elena Adinolfi

  32. Trophic activity of a naturally occurring truncated isoform of the P2X7 receptor

    Article • The FASEB Journal, May 2010, Federation of American Societies For Experimental Biology (FASEB)

    Professor Elena Adinolfi

  33. cAMP efflux from human trophoblast cell lines: a role for multidrug resistance protein (MRP)1 transporter

    Article • Molecular Human Reproduction, March 2010, Oxford University Press (OUP)

    Professor Elena Adinolfi

  34. P2X7: a growth-promoting receptor—implications for cancer

    Article • Purinergic Signalling, March 2009, Springer Science + Business Media

    Francesco Di Virgilio, Professor Elena Adinolfi

  35. Expression of the P2X7 Receptor Increases the Ca2+ Content of the Endoplasmic Reticulum, Activates NFATc1, and Protects from Apoptosis

    Article • Journal of Biological Chemistry, February 2009, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Paolo Pinton, Professor Elena Adinolfi

  36. Somatostatin as a Regulator of First-Trimester Human Trophoblast Functions

    Article • Placenta, August 2008, Elsevier

    Professor Elena Adinolfi

  37. The P2X7 receptor: a key player in IL-1 processing and release

    Article • The Journal of Immunology, December 2007, The American Association of Immunologists

    Professor Elena Adinolfi

  38. Stimulation of Purinergic Receptors Modulates Chemokine Expression in Human Keratinocytes

    Article • Journal of Investigative Dermatology, March 2007, Elsevier

    Professor Elena Adinolfi

  39. Stimulation of P2 (P2X7) receptors in human dendritic cells induces the release of tissue factor-bearing microparticles

    Article • The FASEB Journal, February 2007, Federation of American Societies For Experimental Biology (FASEB)

    Professor Elena Adinolfi

  40. The extracellular nucleotide UTP is a potent inducer of hematopoietic stem cell migration

    Article • Blood, January 2007, American Society of Hematology

    Professor Elena Adinolfi

  41. Stimulation of P2 receptors causes release of IL-1β–loaded microvesicles from human dendritic cells

    Article • Blood, December 2006, American Society of Hematology

    Professor Elena Adinolfi

  42. Involvement of the Purinergic P2X7 Receptor in the Formation of Multinucleated Giant Cells

    Article • The Journal of Immunology, November 2006, The American Association of Immunologists

    Professor Elena Adinolfi

  43. The P2X7 Receptor: A Key Player in IL-1 Processing and Release

    Article • The Journal of Immunology, March 2006, The American Association of Immunologists

    Professor Elena Adinolfi

  44. P2X7 receptor: Death or life?

    Article • Purinergic Signalling, July 2005, Springer Science + Business Media

    Professor Elena Adinolfi

  45. Pseudoapoptosis Induced by Brief Activation of ATP-gated P2X7 Receptors

    Article • Journal of Biological Chemistry, June 2005, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Elena Adinolfi

  46. Basal Activation of the P2X7 ATP Receptor Elevates Mitochondrial Calcium and Potential, Increases Cellular ATP Levels, and Promotes Serum-independent Growth

    Article • Molecular Biology of the Cell, April 2005, American Society for Cell Biology (ASCB)

    Professor Elena Adinolfi

  47. The Antibiotic Polymyxin B Modulates P2X7 Receptor Function

    Article • The Journal of Immunology, September 2004, The American Association of Immunologists

    Professor Elena Adinolfi

  48. Enhanced P2X7 Activity in Human Fibroblasts From Diabetic Patients: A Possible Pathogenetic Mechanism for Vascular Damage in Diabetes

    Article • Arteriosclerosis Thrombosis and Vascular Biology, July 2004, Wolters Kluwer Health

    Professor Elena Adinolfi

  49. Tyrosine Phosphorylation of HSP90 within the P2X7 Receptor Complex Negatively Regulates P2X7 Receptors

    Article • Journal of Biological Chemistry, July 2003, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Elena Adinolfi

  50. P2X7 receptor expression in evolutive and indolent forms of chronic B lymphocytic leukemia

    Article • Blood, January 2002, American Society of Hematology

    Professor Elena Adinolfi

  51. Human Leukocyte Antigen-A,-B,-C and -DR Alleles and Soluble Human Leukocyte Antigen Class I Serum Level in Ménière's Disease

    Article • Acta Oto-Laryngologica, January 2002, Taylor & Francis

    Professor Elena Adinolfi

  52. Increased Proliferation Rate of Lymphoid Cells Transfected with the P2X7 ATP Receptor

    Article • Journal of Biological Chemistry, November 1999, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Elena Adinolfi

  53. Homology modeling and active-site residues probing of the thermophilicAlicyclobacillus acidocaldariusesterase 2

    Article • Protein Science, January 1999, Wiley

    Professor Elena Adinolfi

  54. Overexpression and properties of a new thermophilic and thermostable esterase from Bacillus acidocaldarius with sequence similarity to hormone-sensitive lipase subfamily

    Article • Biochemical Journal, May 1998, Portland Press Ltd.

    Professor Elena Adinolfi