All Stories

  1. Low‐dose ketamine improves animals' locomotor activity and decreases brain oxidative stress and inflammation in ammonia‐induced neurotoxicity
  2. Ion channels involved in inflammation and pain in osteoarthritis and related musculoskeletal disorders
  3. The Effect of CaV1.2 Inhibitor Nifedipine on Chondrogenic Differentiation of Human Bone Marrow or Menstrual Blood-Derived Mesenchymal Stem Cells and Chondrocytes
  4. “Self-Healing”: A Novel and Integrated Multimodal Concept for the Management of Musculoskeletal Pain
  5. Osteoarthritis
  6. Intra-Articular Injection of Platelet-Rich Plasma Is More Effective than Hyaluronic Acid or Steroid Injection in the Treatment of Mild to Moderate Knee Osteoarthritis: A Prospective, Randomized, Triple-Parallel Clinical Trial
  7. Osteoarthritis endotype discovery via clustering of biochemical marker data
  8. Minimally Invasive Cell-Based Therapy for Symptomatic Bone Marrow Lesions of the Knee: A Prospective Clinical Study at 1 Year
  9. Predicting osteoarthritis onset and progression with 3D texture analysis of cartilage MRI DESS: 6‐Year data from osteoarthritis initiative
  10. Magneto-Immunoassay for the Detection and Quantification of Human Growth Hormone
  11. Exploring the translational potential of clusterin as a biomarker of early osteoarthritis
  12. Therapeutic Perspectives for the Clinical Application of Umbilical Cord Hematopoietic and Mesenchymal Stem Cells: Overcoming Complications Arising After Allogeneic Hematopoietic Stem Cell Transplantation
  13. A new immunometabolic perspective of intervertebral disc degeneration
  14. A White Paper on Collagen Hydrolyzates and Ultrahydrolyzates: Potential Supplements to Support Joint Health in Osteoarthritis?
  15. Cardiovascular Drugs and Osteoarthritis: Effects of Targeting Ion Channels
  16. Early-stage symptomatic osteoarthritis of the knee — time for action
  17. Molecular-Morphological Relationships of the Scaffold Protein FKBP51 and Inflammatory Processes in Knee Osteoarthritis
  18. Exogenous stromal cell-derived factor-1 (SDF-1) suppresses the NLRP3 inflammasome and inhibits pyroptosis in synoviocytes from osteoarthritic joints via activation of the AMPK signaling pathway
  19. A Prospective Study Comparing Leukocyte-Poor Platelet-Rich Plasma Combined with Hyaluronic Acid and Autologous Microfragmented Adipose Tissue in Patients with Early Knee Osteoarthritis
  20. The Effect of Platelet-Rich Plasma on the Intra-Articular Microenvironment in Knee Osteoarthritis
  21. Drug‐induced organ injury in coronavirus disease 2019 pharmacotherapy: Mechanisms and challenges in differential diagnosis and potential protective strategies
  22. Monomeric C reactive protein (mCRP) regulates inflammatory responses in human and mouse chondrocytes
  23. Exogenous Stromal Cell-Derived Factor-1 (SDF-1) Suppresses the NLRP3 Inflammasome and Inhibits Pyroptosis in Synoviocytes from Osteoarthritic Joints via Activation of the AMPK Signaling Pathway
  24. Podcasting: An innovative tool for enhanced osteoarthritis education and research dissemination
  25. The role of metabolism in chondrocyte dysfunction and the progression of osteoarthritis
  26. An Update on the Role of Leptin in the Immuno-Metabolism of Cartilage
  27. Targeting mitochondrial dysfunction with small molecules in intervertebral disc aging and degeneration
  28. Reevolution of Tissue Regeneration: From Recent Advances in Adipose Stem Cells to Novel Therapeutic Approaches
  29. Neuroscience and Neuroimmunology Solutions for Osteoarthritis Pain: Biological Drugs, Growth Factors, Peptides and Monoclonal Antibodies Targeting Peripheral Nerves
  30. The future of deep phenotyping in osteoarthritis: how can high throughput omics technologies advance our understanding of the cellular and molecular taxonomy of the disease?
  31. Elephants, Mobility and Captivity: What Can These Mighty and Majestic Animals Teach Us About Joint Health and Osteoarthritis?
  32. Neuroscience and Neuroimmunology Solutions for Osteoarthritis Pain: Biological Drugs, Growth Factors, Peptides and Monoclonal Antibodies Targeting Peripheral Nerves
  33. Prospective study comparing leukocyte-poor platelet rich plasma combined with hyaluronic acid and autologous microfragmented adipose tissue in patients with early knee osteoarthritis.
  34. Biosensors for the Multiplex Detection of Inflammatory Disease Biomarkers
  35. Elephants, Mobility and Captivity: What Can These Mighty and Majestic Animals Teach Us About Joint Health and Osteoarthritis?
  36. Multiplexed Nanobiosensors: Current Trends in Early Diagnostics
  37. Characterization of Individuals with Osteoarthritis in the United States and Their Use of Prescription and Over-the-Counter Supplements
  38. Non-surgical management of knee osteoarthritis: comparison of ESCEO and OARSI 2019 guidelines
  39. Over-Production of Therapeutic Growth Factors for Articular Cartilage Regeneration by Protein Production Platforms and Protein Packaging Cell Lines
  40. Physiological Effects of the Electrogenic Current Generated by the Na /K Pump in Mammalian Articular Chondrocytes
  41. Clusterin secretion is attenuated by the proinflammatory cytokines interleukin‐1β and tumor necrosis factor‐α in models of cartilage degradation
  42. Over-production of Therapeutic Growth Factors for Articular Cartilage Regeneration by Protein Production Platforms and Protein Packaging Cell Lines
  43. COVID-19, osteoarthritis and women's health
  44. Alterations in the chondrocyte surfaceome in response to pro-inflammatory cytokines
  45. Combining segmental bulk- and single-cell RNA-sequencing to define the chondrocyte gene expression signature in the murine knee joint
  46. Multi-classifier prediction of knee osteoarthritis progression from incomplete imbalanced longitudinal data
  47. Clusterin secretion is attenuated by pro-inflammatory cytokines in culture models of cartilage degradation
  48. Nanotechnological Strategies for Osteoarthritis Diagnosis, Monitoring, Clinical Management, and Regenerative Medicine: Recent Advances and Future Opportunities
  49. Pro-inflammatory Cytokines Drive Deregulation of Potassium Channel Expression in Primary Synovial Fibroblasts
  50. A consensus-based framework for conducting and reporting osteoarthritis phenotype research
  51. Vertically aligned carbon nanotube micropillars induce unidirectional chondrocyte orientation
  52. Biomarkers of fitness and welfare in dairy cattle: healthy productivity
  53. Cell and Gene Therapy for Spine Regeneration
  54. Recent advances in understanding the phenotypes of osteoarthritis
  55. Biomarkers of fitness and welfare in dairy animals: healthy living
  56. The Antihypertensive Drug Nifedipine Modulates the Metabolism of Chondrocytes and Human Bone Marrow-Derived Mesenchymal Stem Cells
  57. Alterations in the chondrocyte surfaceome in response to pro-inflammatory cytokines
  58. Over-Production of Therapeutic Growth Factors for Cartilage Regeneration by Protein Production Platforms and Protein Packaging Cell Lines: A Narrative Review of the Current State-of-the-Art
  59. Coll2-1 and Coll2-1NO2 as exemplars of collagen extracellular matrix turnover - biomarkers to assist the treatment of osteoarthritis?
  60. Tofacitinib and TPCA-1 exert chondroprotective effects on extracellular matrix turnover in bovine articular cartilage ex vivo
  61. Osteoarthritis (OA): A Modern Disease of the Anthropocene Era
  62. The Role of Advanced MRI in the Development of Treat-to-Target Therapeutic Strategies, Patient Stratification and Phenotyping in Rheumatoid Arthritis
  63. The Antihypertensive Drug Nifedipine Modulates the Metabolism of Chondrocytes and Human Bone Marrow-Derived Mesenchymal Stem Cells
  64. Molecular phenotyping of the surfaceome of migratory chondroprogenitors and mesenchymal stem cells using biotinylation, glycocapture and quantitative LC-MS/MS proteomic analysis
  65. Establishing outcome measures in early knee osteoarthritis
  66. Molecular phenotyping of the surfaceome of migratory chondroprogenitors and mesenchymal stem cells using biotinylation, glycocapture and quantitative LC-MS/MS proteomic analysis
  67. Strategies for optimising musculoskeletal health in the 21st century
  68. Natural Molecules for Healthy Lifestyles: Oleocanthal from Extra Virgin Olive Oil
  69. Adipokines: Linking metabolic syndrome, the immune system, and arthritic diseases
  70. Osteoarthritis phenotypes and novel therapeutic targets
  71. Le « channelome » du chondrocyte. Revue narrative
  72. Uptake of the OMERACT-OARSI Hip and Knee Osteoarthritis Core Outcome Set: Review of Randomized Controlled Trials from 1997 to 2017
  73. IQGAP1, AmotL2, and FKBP51 Scaffoldins in the Glioblastoma Microenvironment
  74. Comment on: Efficacy of Curcumin and Boswellia for knee osteoarthritis: Systematic review and meta-analysis
  75. The OMERACT-OARSI Core Domain Set for Measurement in Clinical Trials of Hip and/or Knee Osteoarthritis
  76. A correlation between intestinal microbiota dysbiosis and osteoarthritis
  77. A systematic review of osteoarthritis prevention and management with dietary phytochemicals from foods
  78. Homeobox Genes and Homeodomain Proteins: New Insights into Cardiac Development, Degeneration and Regeneration
  79. Molecular taxonomy of osteoarthritis for patient stratification, disease management and drug development
  80. The chondrocyte channelome: A narrative review
  81. The Potential of Menstrual Blood-Derived Mesenchymal Stem Cells for Cartilage Repair and Regeneration: Novel Aspects
  82. A Novel High Sensitivity Type II Collagen Blood-Based Biomarker, PRO-C2, for Assessment of Cartilage Formation
  83. The Role of Physical Stimuli on Calcium Channels in Chondrogenic Differentiation of Mesenchymal Stem Cells
  84. Natural Products for Promoting Joint Health and Managing Osteoarthritis
  85. Aggrecanase degradation of type III collagen is associated with clinical knee pain
  86. What is the evidence for a role for diet and nutrition in osteoarthritis?
  87. Adipokines and inflammation: is it a question of weight?
  88. Which supplements can I recommend to my osteoarthritis patients?
  89. A Comprehensive Review of Stem Cells for Cartilage Regeneration in Osteoarthritis
  90. Bioengineered Scaffolds for Stem Cell Applications in Tissue Engineering and Regenerative Medicine
  91. Biomaterials for Regenerative Medicine: Historical Perspectives and Current Trends
  92. Development and use of biochemical markers in osteoarthritis
  93. Extracellular genomic biomarkers of osteoarthritis
  94. Gestation changes sodium pump isoform expression, leading to changes in ouabain sensitivity, contractility, and intracellular calcium in rat uterus
  95. The Na, K-ATPase β-Subunit Isoforms Expression in Glioblastoma Multiforme: Moonlighting Roles
  96. Aging and osteoarthritis: Central role of the extracellular matrix
  97. Biochemical marker discovery, testing and evaluation for facilitating OA drug discovery and development
  98. Progranulin as a biomarker and potential therapeutic agent
  99. Soluble biochemical markers of osteoarthritis: Are we close to using them in clinical practice?
  100. Engineered cartilage regeneration from adipose tissue derived-mesenchymal stem cells: A morphomolecular study on osteoblast, chondrocyte and apoptosis evaluation
  101. Alterations in IQGAP1 expression and localization in colorectal carcinoma and liver metastases following oxaliplatin-based chemotherapy
  102. Commitment of Scaffold Proteins in the Onco-Biology of Human Colorectal Cancer and Liver Metastases after Oxaliplatin-Based Chemotherapy
  103. LEF1-mediated MMP13 gene expression is repressed by SIRT1 in human chondrocytes
  104. The role of metabolism in the pathogenesis of osteoarthritis
  105. The minor collagens in articular cartilage
  106. Chondrocyte secretome: a source of novel insights and exploratory biomarkers of osteoarthritis
  107. Osteoarthritis Year in Review 2016: biomarkers (biochemical markers)
  108. IQGAP1 in Podosomes/Invadosomes Is Involved in the Progression of Glioblastoma Multiforme Depending on the Tumor Status
  109. IQGAP1 in Podosomes/Invadosomes Is Involved in the Progression of Glioblastoma Multiforme Depending on the Tumor Status
  110. IQGAP1 in Podosome /Invadosome is Involved in the Progression of Glioblastoma Multiforme Depending on the Tumor Status
  111. The Potency of Induced Pluripotent Stem Cells in Cartilage Regeneration and Osteoarthritis Treatment
  112. Adipose, Bone Marrow and Synovial Joint-Derived Mesenchymal Stem Cells for Cartilage Repair
  113. An update on the pathophysiology of osteoarthritis
  114. IQGAP1 in Podosome /Invadosome is Involved in the Progression of Glioblastoma Multiforme Depending on the Tumor Status
  115. Age-Related Alterations in Signaling Pathways in Articular Chondrocytes: Implications for the Pathogenesis and Progression of Osteoarthritis - A Mini-Review
  116. Applying Proteomics to Study Crosstalk at the Cartilage-Subchondral Bone Interface in Osteoarthritis: Current Status and Future Directions
  117. In vitro models of cancer stem cells and clinical applications
  118. Reply to “Comment on: Inflammatory mediators in osteoarthritis: A critical review of the state-of-the art, prospects, and future challenges”
  119. The Role of Sirtuins in Cartilage Homeostasis and Osteoarthritis
  120. Altered joint tribology in osteoarthritis: Reduced lubricin synthesis due to the inflammatory process. New horizons for therapeutic approaches
  121. Osteoarthritis biomarkers derived from cartilage extracellular matrix: Current status and future perspectives
  122. Pelleted Bone Marrow Derived Mesenchymal Stem Cells Are Better Protected from the Deleterious Effects of Arthroscopic Heat Shock
  123. The Need for Predictive, Prognostic, Objective and Complementary Blood-Based Biomarkers in Osteoarthritis (OA)
  124. Immune Modulation of Inammation in Neurodegenerative Diseases: Alzheimer’s Disease and Amyotrophic Lateral Sclerosis
  125. Mesenchymal stem cells: Identification, phenotypic characterization, biological properties and potential for regenerative medicine through biomaterial micro-engineering of their niche
  126. Inflammatory mediators in osteoarthritis: A critical review of the state-of-the-art, current prospects, and future challenges
  127. Mesenchymal stem cells in regenerative medicine: Focus on articular cartilage and intervertebral disc regeneration
  128. Faculty of 1000 evaluation for Aging Promotes SIRT3-dependent Cartilage SOD2 Acetylation and Osteoarthritis.
  129. Faculty of 1000 evaluation for Elucidating the Molecular Composition of Cartilage by Proteomics.
  130. Atenolol Reduces Leishmania major-Induced Hyperalgesia and TNF-α Without Affecting IL-1β or Keratinocyte Derived Chemokines (KC)
  131. Na,K-ATPase Isozymes in Colorectal Cancer and Liver Metastases
  132. Post-operative rehabilitation and nutrition in osteoarthritis
  133. Osteoarthritis year in review 2015: soluble biomarkers and the BIPED criteria
  134. Effect of Prenatal and Neonatal Anti-Androgen Flutamide Treatment on Aquaporin 5 Expression in the Adult Porcine Ovary
  135. Biomarkers of (osteo)arthritis
  136. Label-free proteomic analysis of the hydrophobic membrane protein complement in articular chondrocytes: a technique for identification of membrane biomarkers
  137. The potential of lipocalin-2/NGAL as biomarker for inflammatory and metabolic diseases
  138. Leptin in osteoarthritis: Focus on articular cartilage and chondrocytes
  139. Mesenchymal Stem Cells and their Potential for Microengineering the Chondrocyte Niche
  140. Cobalt chloride doping in racehorses: Concerns over a potentially lethal practice
  141. Biomarkers of Chondrocyte Apoptosis and Autophagy in Osteoarthritis
  142. Comparative Medicine in the Twenty-First Century: Where are We Now and Where Do We Go from Here?
  143. Voltage-Dependent Calcium Channels in Chondrocytes: Roles in Health and Disease
  144. Osteoarthritis in the XXIst Century: Risk Factors and Behaviours that Influence Disease Onset and Progression
  145. Ameliorative Effects of PACAP against Cartilage Degeneration. Morphological, Immunohistochemical and Biochemical Evidence from in Vivo and in Vitro Models of Rat Osteoarthritis
  146. Physicochemical and Biomechanical Stimuli in Cell-Based Articular Cartilage Repair
  147. Chondrosenescence: Definition, hallmarks and potential role in the pathogenesis of osteoarthritis
  148. The crossroads between cancer stem cells and aging
  149. A machine learning heuristic to identify biologically relevant and minimal biomarker panels from omics data
  150. Physiology and Pathophysiology of Musculoskeletal Aging
  151. Corrigendum to: What is the current status of chondroitin sulfate and glucosamine for the treatment of knee osteoarthritis? Maturitas 78 (2014) 184–187
  152. High hopes for cannabinoid agonists in the treatment of rheumatic diseases
  153. Ser/Thr-phosphoprotein phosphatases in chondrogenesis: neglected components of a two-player game
  154. Biosynthesis of collagen I, II, RUNX2 and lubricin at different time points of chondrogenic differentiation in a 3D in vitro model of human mesenchymal stem cells derived from adipose tissue
  155. Faculty Opinions recommendation of A biphasic multiscale study of the mechanical microenvironment of chondrocytes within articular cartilage under unconfined compression.
  156. Faculty Opinions recommendation of Inflammation induces irreversible biophysical changes in isolated nucleus pulposus cells.
  157. Faculty Opinions recommendation of The Kardashian index: a measure of discrepant social media profile for scientists.
  158. Faculty Opinions recommendation of Publication metrics and success on the academic job market.
  159. Peripheral Calcitonin Gene‐Related Peptide Receptor Activation and Mechanical Sensitization of the Joint in Rat Models of Osteoarthritis Pain
  160. Physical activity ameliorates cartilage degeneration in a rat model of aging: A study on lubricin expression
  161. Faculty Opinions recommendation of Role of dentin matrix protein 1 in cartilage redifferentiation and osteoarthritis.
  162. Faculty Opinions recommendation of The active form of MMP-3 is a marker of synovial inflammation and cartilage turnover in inflammatory joint diseases.
  163. Faculty Opinions recommendation of Targeting pro-inflammatory cytokines following joint injury: acute intra-articular inhibition of interleukin-1 following knee injury prevents post-traumatic arthritis.
  164. What is the current status of chondroitin sulfate and glucosamine for the treatment of knee osteoarthritis?
  165. Chondrocyte and mesenchymal stem cell-based therapies for cartilage repair in osteoarthritis and related orthopaedic conditions
  166. Faculty Opinions recommendation of Effect of physical therapy on pain and function in patients with hip osteoarthritis: a randomized clinical trial.
  167. Lubricin expression in human osteoarthritic knee meniscus and synovial fluid: A morphological, immunohistochemical and biochemical study
  168. Post-operative rehabilitation in osteoarthritis
  169. Post-operative rehabilitation in osteoarthritis 
  170. Faculty Opinions recommendation of A single blunt impact on cartilage promotes fibronectin fragmentation and upregulates cartilage degrading stromelysin-1/matrix metalloproteinase-3 in a bovine ex vivo model.
  171. Faculty Opinions recommendation of Effect of oral glucosamine on joint structure in individuals with chronic knee pain: a randomized, placebo-controlled clinical trial.
  172. Faculty Opinions recommendation of Cav3.2 T-type calcium channel is required for the NFAT-dependent Sox9 expression in tracheal cartilage.
  173. Regulation of chondrogenesis by protein kinase C: Emerging new roles in calcium signalling
  174. Faculty Opinions recommendation of FK506 protects against articular cartilage collagenous extra-cellular matrix degradation.
  175. Faculty Opinions recommendation of Articular cartilage chondrocytes express aromatase and use enzymes involved in estrogen metabolism.
  176. Faculty Opinions recommendation of Underlying molecular mechanisms of DIO2 susceptibility in symptomatic osteoarthritis.
  177. Immunolocalization of aquaporin 5 during rat ovarian follicle development and expansion of the preovulatory cumulus oophorus
  178. Biomarkers of osteoarthritis: translating information from in vitro culture systems to human patients
  179. Effect of osmotic stress on the expression of TRPV4 and BKCa channels and possible interaction with ERK1/2 and p38 in cultured equine chondrocytes
  180. Water intake, faecal output and intestinal motility in horses moved from pasture to a stabled management regime with controlled exercise
  181. Faculty Opinions recommendation of The CRAPome: a contaminant repository for affinity purification-mass spectrometry data.
  182. Faculty Opinions recommendation of Cleaning up the masses: exclusion lists to reduce contamination with HPLC-MS/MS.
  183. Faculty Opinions recommendation of Culture expansion in low-glucose conditions preserves chondrocyte differentiation and enhances their subsequent capacity to form cartilage tissue in three-dimensional culture.
  184. Faculty Opinions recommendation of Mesenchymal stem cells: immune evasive, not immune privileged.
  185. Faculty Opinions recommendation of Cell senescence abrogates the therapeutic potential of human mesenchymal stem cells in the lethal endotoxemia model.
  186. Faculty Opinions recommendation of Cobalt chloride induces neuronal differentiation of human mesenchymal stem cells through upregulation of microRNA-124a.
  187. Effects of cyclic equibiaxial mechanical stretch on α-BK and TRPV4 expression in equine chondrocytes
  188. Antioxidants and Osteoarthritis
  189. Carprofen inhibits the release of matrix metalloproteinases 1, 3, and 13 in the secretome of an explant model of articular cartilage stimulated with interleukin 1β
  190. Faculty Opinions recommendation of NFATc1 and NFATc2 repress spontaneous osteoarthritis.
  191. Faculty Opinions recommendation of Osteoarthritis as an inflammatory disease (osteoarthritis is not osteoarthrosis!).
  192. Faculty Opinions recommendation of Two non-coding RNAs, MicroRNA-101 and HOTTIP contribute cartilage integrity by epigenetic and homeotic regulation of integrin-α1.
  193. Faculty Opinions recommendation of Osteoarthritis year 2013 in review: biomarkers; reflecting before moving forward, one step at a time.
  194. Faculty Opinions recommendation of Differentiation of muscle, fat, cartilage, and bone from progenitor cells present in a bone-derived clonal cell population: effect of dexamethasone.
  195. Faculty Opinions recommendation of Flexural properties of native and tissue-engineered human septal cartilage.
  196. Faculty Opinions recommendation of Differentiation of adipose-derived stem cells into contractile smooth muscle cells induced by transforming growth factor-beta1 and bone morphogenetic protein-4.
  197. Faculty Opinions recommendation of Cytokine signaling-1 suppressor is inducible by IL-1beta and inhibits the catabolic effects of IL-1beta in chondrocytes: its implication in the paradoxical joint-protective role of IL-1beta.
  198. Aquaporin Water Channels in the Mammary Gland: From Physiology to Pathophysiology and Neoplasia
  199. Faculty Opinions recommendation of Detection of tumor necrosis factor alpha but not tumor necrosis factor beta in rheumatoid arthritis synovial fluid and serum.
  200. Faculty Opinions recommendation of Migratory chondrogenic progenitor cells from repair tissue during the later stages of human osteoarthritis.
  201. Faculty Opinions recommendation of iTRAQ-based proteomics reveals novel biomarkers of osteoarthritis.
  202. Faculty Opinions recommendation of In Vivo luminescent imaging of NF-κB activity and serum cytokine levels predict pain sensitivities in a rodent model of osteoarthritis.
  203. Faculty Opinions recommendation of Hypercholesterolemia boosts joint destruction in chronic arthritis. An experimental model aggravated by foam macrophage infiltration.
  204. Faculty Opinions recommendation of Interleukin-1 beta and tumor necrosis factor alpha inhibit migration activity of chondrogenic progenitor cells from non-fibrillated osteoarthritic cartilage.
  205. Faculty Opinions recommendation of An explorative study comparing levels of soluble mediators in control and osteoarthritic synovial fluid.
  206. Faculty Opinions recommendation of Hypoxia promotes redifferentiation and suppresses markers of hypertrophy and degeneration in both healthy and osteoarthritic chondrocytes.
  207. Faculty Opinions recommendation of Release of cartilage oligomeric matrix protein (COMP) into joint fluid after knee injury and in osteoarthritis.
  208. Faculty Opinions recommendation of IL-17 inhibits chondrogenic differentiation of human mesenchymal stem cells.
  209. Faculty Opinions recommendation of Evidence that TNF-β (lymphotoxin α) can activate the inflammatory environment in human chondrocytes.
  210. Faculty Opinions recommendation of Chondrogenesis of mesenchymal stem cells in an osteochondral environment is mediated by the subchondral bone.
  211. Faculty Opinions recommendation of Macrophage migration inhibitory factor regulates AKT signaling in hypoxic culture to modulate senescence of human mesenchymal stem cells.
  212. Application of Machine Learning to Proteomics Data: Classification and Biomarker Identification in Postgenomics Biology
  213. Analysis of mass spectrometry data from the secretome of an explant model of articular cartilage exposed to pro-inflammatory and anti-inflammatory stimuli using machine learning
  214. Chondrocyte channel transcriptomics
  215. The Future of Osteoarthritis Therapeutics: Emerging Biological Therapy
  216. The Future of Osteoarthritis Therapeutics: Targeted Pharmacological Therapy
  217. Bacterial lipopolysaccharides form procollagen-endotoxin complexes that trigger cartilage inflammation and degeneration: implications for the development of rheumatoid arthritis
  218. Curcumin reduces prostaglandin E2, matrix metalloproteinase-3 and proteoglycan release in the secretome of interleukin 1β-treated articular cartilage
  219. Curcumin reduces prostaglandin E2, matrix metalloproteinase-3 and proteoglycan release in the secretome of interleukin 1β-treated articular cartilage
  220. Aquaporin water channels in the canine gubernaculum testis
  221. Osteogenic effects of resveratrol in vitro: potential for the prevention and treatment of osteoporosis
  222. Expression and function of K(ATP) channels in normal and osteoarthritic human chondrocytes: Possible role in glucose sensing
  223. Faculty Opinions recommendation of The cell surface proteome of human mesenchymal stromal cells.
  224. Faculty Opinions recommendation of Proteome analysis during chondrocyte differentiation in a new chondrogenesis model using human umbilical cord stroma mesenchymal stem cells.
  225. Exploring the serum proteome in dogs: Setting the scene for the discovery of new biomarkers in canine lymphoma
  226. Tissue Engineered Animal Sparing Models for the Study of Joint and Muscle Diseases
  227. High-throughput proteomic analysis of the cartilage secretome for identification of inflammatory biomarkers
  228. Sample classification and identification of biomarkers in the cartilage secretome from mass spectrometry datasets using machine learning
  229. Physiological effects of oral glucosamine on joint health: current status and consensus on future research priorities
  230. Benzamil sensitive ion channels contribute to volume regulation in canine chondrocytes
  231. Nonpharmacological modalities, nutraceuticals and dietary supplements as therapies
  232. Curcumin Enhances the Effect of Chemotherapy against Colorectal Cancer Cells by Inhibition of NF-κB and Src Protein Kinase Signaling Pathways
  233. Curcumin: a new paradigm and therapeutic opportunity for the treatment of osteoarthritis: curcumin for osteoarthritis management
  234. Physiology and pathophysiology of musculoskeletal aging: current research trends and future priorities
  235. Soluble Proteomic Biomakers in the Management of Arthritis
  236. Antioxidants in the Treatment of Osteoarthritis and Bone Mineral Loss
  237. Osteoarthritis year 2012 in review: biomarkers
  238. Potassium channels in articular chondrocytes
  239. Intersection of Inflammation and Herbal Medicine in the Treatment of Osteoarthritis
  240. Resveratrol Modulates Interleukin-1 -induced Phosphatidylinositol 3-Kinase and Nuclear Factor  B Signaling Pathways in Human Tenocytes
  241. Editorial: [Hot Topic: Epigenetics in Arthritis]
  242. Sirt-1 Is Required for the Inhibition of Apoptosis and Inflammatory Responses in Human Tenocytes
  243. Identification and phenotypic characterisation of chondroprogenitor cells for the repair of equine articular cartilage
  244. Expression of aquaporin water channels in canine fetal adnexa in respect to the regulation of amniotic fluid production and absorption
  245. Resveratrol Mediated Modulation of Sirt-1/Runx2 Promotes Osteogenic Differentiation of Mesenchymal Stem Cells: Potential Role of Runx2 Deacetylation
  246. Nutraceuticals: From Research to Legal and Regulatory Affairs
  247. Na+, K+-ATPase Subunit Composition in a Human Chondrocyte Cell Line; Evidence for the Presence of α1, α3, β1, β2 and β3 Isoforms
  248. Expression of Transient Receptor Potential Vanilloid (TRPV) Channels in Different Passages of Articular Chondrocytes
  249. Year in review: biomarkers
  250. Proteomic and bioinformatic analysis of hydrophobic membrane protein extracts reveals the presence of several novel CD antigens, glucose transporters and voltage gated anion channels in articular chondrocytes
  251. Scientific Evidence and Rationale for the Development of Curcumin and Resveratrol as Nutraceutricals for Joint Health
  252. Three‐Dimensional, High‐Density and Tissue Engineered Culture Models of Articular Cartilage
  253. Proteomic Profiling and Its Applications to Muscle Aging and Sarcopenia
  254. Is there any scientific evidence for the use of glucosamine in the management of human osteoarthritis?
  255. Glucose: an energy currency and structural precursor in articular cartilage and bone with emerging roles as an extracellular signaling molecule and metabolic regulator
  256. Botanical Extracts from Rosehip (Rosa canina), Willow Bark (Salix alba), and Nettle Leaf (Urtica dioica) Suppress IL-1β-Induced NF-κB ...
  257. The biology of equine mesenchymal stem cells: phenotypic characterization, cell surface markers and multilineage differentiation
  258. IGF-1 and PDGF-bb Suppress IL-1β-Induced Cartilage Degradation through Down-Regulation of NF-κB Signaling: Involvement of Src/PI-3K/AKT Pathway
  259. Hypoxia and a hypoxia mimetic up-regulate matrix metalloproteinase 2 and 9 in equine laminar keratinocytes
  260. Identification and validation of early biomarkers of osteoarthritis in companion animals: Are we ready for the challenge?
  261. T105 ACUTE BLOCKADE OF CALCITONIN GENE-RELATED PEPTIDE RECEPTORS INHIBITS RESPONSES OF KNEE JOINT PRIMARY AFFERENTS IN THE MIA MODEL OF OSTEOARTHRITIS
  262. 453 NOVEL BIOINFORMATIC APPROACHES FOR IDENTIFYING PUTATIVE OA BIOMARKERS: LABEL-FREE QUANTIFICATION OF PROTEINS IN THE SECRETÓME OF ARTICULAR CARTILAGE
  263. 451 STRATEGIES FOR OPTIMISING PROTEOMIC STUDIES OF THE CARTILAGE SECRETOME: ESTABLISHING THE TIME COURSE FOR PROTEIN RELEASE AND EVALUATING RESPONSES OF EXPLANT CULTURES TO IL-1β, TNF-α AND CARPROFEN
  264. From Multipotent Cells to Fully Differentiated Connective Tissue Cells for Regenerative Medicine: Emerging Applications of Mesenchymal Stem Cells
  265. The role of the membrane potential in chondrocyte volume regulation
  266. Curcumin Modulates Nuclear Factor κB (NF-κB)-mediated Inflammation in Human Tenocytes in Vitro
  267. High throughput proteomic analysis of the secretome in an explant model of articular cartilage inflammation
  268. Applications of Mesenchymal Stem Cells in Cartilage Tissue Engineering- Part 1
  269. Biomarkers of Osteoarthritis: A Review of Recent Research Progress on Soluble Biochemical Markers, Published Patents and Areas for Future Development
  270. Three‐dimensional high‐density co‐culture with primary tenocytes induces tenogenic differentiation in mesenchymal stem cells
  271. Transient receptor potential channels: Emerging roles in health and disease
  272. Cellular localization of aquaporins along the secretory pathway of the lactating bovine mammary gland: An immunohistochemical study
  273. Neuronal Responses in the Brainstem and Hypothalamic Nuclei Following Insulin Treatment During the Late Follicular Phase in the Ewe
  274. Resveratrol-mediated SIRT-1 Interactions with p300 Modulate Receptor Activator of NF- B Ligand (RANKL) Activation of NF- B Signaling and Inhibit Osteoclastogenesis in Bone-derived Cells
  275. Applications of Proteomics to Osteoarthritis, a Musculoskeletal Disease Characterized by Aging
  276. Applications of Mesenchymal Stem Cells in Cartilage Tissue Engineering- Part 1
  277. Biomarkers of Osteoarthritis: A Review of Recent Research Progress on Soluble Biochemical Markers, Published Patents and Areas for Future Development
  278. Applications of proteomics in cartilage biology and osteoarthritis research
  279. Equine transcriptome quantification using human GeneChip arrays can be improved using genomic DNA hybridisation and probe selection
  280. I-09 DIETARY SUPPLEMENTS IN OA: REAL OPPORTUNITY OR UTOPIA?
  281. 214 ROLE OF K(ATP) CHANNELS IN MODULATING GLUT-1 CONTENT IN NORMAL AND OSTEOARTHRITIC HUMAN CHONDROCYTES
  282. 258 EXPRESSION OF TRANSIENT RECEPTOR POTENTIAL VANILLOID (TRPV) CHANNELS IN DIFFERENT PASSAGES OF EQUINE ARTICULAR CHONDROCYTES
  283. 384 COMBINING CHONDROCYTE GENE EXPRESSION, LITERATURE MINING AND PATHWAY/NETWORK ANALYSIS TO EXTRACT BIOLOGICAL INSIGHTS FROM SMALL-SCALE MICROARRAY DATA
  284. 503 QUANTITATIVE VALIDATION OF PROTEINS IDENTIFIED IN THE CARTILAGE SECRETOME IN AN EXPLANT MODEL OF EARLY OSTEOARTHRITIS
  285. 121 PROTEOMIC ANALYSIS OF THE SECRETOME IN AN EXPLANT MODEL OF CANINE ARTICULAR CARTILAGE
  286. The impact of maternal protein restriction during rat pregnancy upon renal expression of angiotensin receptors and vasopressin-related aquaporins
  287. Identification, validation and qualification of biomarkers for osteoarthritis in humans and companion animals: Mission for the next decade
  288. Biomarkers in veterinary medicine: Towards targeted, individualised therapies for companion animals
  289. Curcumin mediated suppression of nuclear factor-κB promotes chondrogenic differentiation of mesenchymal stem cells in a high-density co-culture microenvironment
  290. Expression of the plasma membrane markers aquaporin 1 (AQP1), glucose transporter 1 (GLUT1) and Na, K-ATPase in canine mammary glands and mammary tumours
  291. Curcumin synergizes with resveratrol to stimulate the MAPK signaling pathway in human articular chondrocytes in vitro
  292. Glucose transporter Glut-1 is detectable in peri-necrotic regions in many human tumor types but not normal tissues: Study using tissue microarrays
  293. Expression and Distribution of Na, K-ATPase Isoforms in the Human Uterus
  294. Expression of aquaporin 1 (AQP1) in human synovitis
  295. Immunohistochemical evidence for expression of fast-twitch type sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA1) in German shepherd dogs with dilated cardiomyopathy myocardium
  296. Characterization of a stretch‐activated potassium channel in chondrocytes
  297. Biological actions of curcumin on articular chondrocytes
  298. The lysosomal trafficking regulator interacting protein-5 localizes mainly in epithelial cells
  299. Differential cellular expression of FXYD1 (phospholemman) and FXYD2 (gamma subunit of Na, K-ATPase) in normal human tissues: A study using high density human tissue microarrays
  300. Distribution, expression and functional effects of small conductance Ca-activated potassium (SK) channels in rat myometrium
  301. Matrix metalloproteinases in inflammatory pathologies of the horse
  302. Mesenchymal stem cells in regenerative medicine: Opportunities and challenges for articular cartilage and intervertebral disc tissue engineering
  303. The emerging chondrocyte channelome
  304. On Some Aspects of the Thermodynamic of Membrane Recycling Mediated by Fluid Phase Endocytosis: Evaluation of Published Data and Perspectives
  305. Targeting Matrix Metalloproteinases in Inflammatory Conditions
  306. Biomarkers in veterinary medicine: establishing a new international forum for veterinary biomarker research
  307. Applications of Tissue Microarrays in Renal Physiology and Pathology
  308. Synergistic chondroprotective effects of curcumin and resveratrol in human articular chondrocytes: inhibition of IL-1β-induced NF-κB-mediated inflammation and apoptosis
  309. Interleukin‐1β–Induced Extracellular Matrix Degradation and Glycosaminoglycan Release Is Inhibited by Curcumin in an Explant Model of Cartilage Inflammation
  310. Impaired glucose transporter-1 degradation and increased glucose transport and oxidative stress in response to high glucose in chondrocytes from osteoarthritic versus normal human cartilage
  311. Proteomic identification and profiling of canine lymphoma patients
  312. Proteomic identification and profiling of canine lymphoma patients*
  313. Effects of hypoxia on glucose transport in primary equine chondrocytes in vitro and evidence of reduced GLUT1 gene expression in pathologic cartilage in vivo
  314. Comment on: comparison between chondroprotective effects of glucosamine, curcumin and diacerein in IL-1β-stimulated C-28/I2 chondrocytes
  315. The contribution of the synovium, synovial derived inflammatory cytokines and neuropeptides to the pathogenesis of osteoarthritis
  316. Resveratrol suppresses interleukin-1β-induced inflammatory signaling and apoptosis in human articular chondrocytes: Potential for use as a novel nutraceutical for the treatment of osteoarthritis
  317. Co-culture of canine mesenchymal stem cells with primary bone-derived osteoblasts promotes osteogenic differentiation
  318. A40 PROTEOMIC IDENTIFICATION OF SECRETED BIOMARKERS IN AN EXPLANT MODEL OF EARLY OSTEOARTHRITIS
  319. 202 DYSREGULATION OF GLUCOSE TRANSPORT AND GLUT-1 PROTEIN IN OSTEOARTHRITIC CHONDROCYTES IN RESPONSE TO HIGH EXTRACELLULAR GLUCOSE
  320. 516 CURCUMIN (DIFERULOYLMETHANE) BLOCKS Il-1β STIMULATED GLYCOSAMINOGLYCAN AND PROSTAGLANDIN E2 RELEASE FROM CARTILAGE EXPLANTS IN AN IN VITRO MODEL OF OSTEOARTHRITIS
  321. Aquaporin expression in the human intervertebral disc
  322. Expression of glucose transporters GLUT-1, GLUT-3, GLUT-9 and HIF-1α in normal and degenerate human intervertebral disc
  323. Diverse Roles of Integrin Receptors in Articular Cartilage
  324. Facilitative Glucose Transporters in Articular Chondrocytes
  325. Articular Cartilage: Structure, Function, and Pathophysiology
  326. Concluding Remarks
  327. Does Arthritis Have a Nutritional Etiology?
  328. Glucose Transporter Expression and Regulation in Embryonic and Mesenchymal Stem Cells
  329. Glucose Transporters in the Intervertebral Disc
  330. Glucose: An Essential Metabolite and Structural Precursor for Articular Cartilage
  331. Integrins in Articular Cartilage
  332. Introduction
  333. Introduction
  334. Mammalian Sugar Transporter Families: GLUT and SGLT
  335. Metabolic Dysfunction in Arthritis
  336. Molecular Diversity of Facilitative Glucose Transporters in Articular Chondrocytes
  337. Regulation of Glucose Transport by Nonsteroidal Anti-inflammatory Drugs
  338. 224 DIFFERENCES IN INTRACELLULAR Na+ AND K+ CONCENTRATIONS BY SUPERFICIAL AND DEEP HUMAN ARTICULAR CHONDROCYTES
  339. 225 EXTRACELLULAR NA+ CONCENTRATION IN HUMAN CARTILAGE: IMPLICATIONS FOR IGF, IL-1 AND TNFα SYNTHESIS BY CHONDROCYTES
  340. Chondrogenesis, osteogenesis and adipogenesis of canine mesenchymal stem cells: a biochemical, morphological and ultrastructural study
  341. Colony-stimulating factors in veterinary medicine: An unexplored potential
  342. Suppression of NF-κB activation by curcumin leads to inhibition of expression of cyclo-oxygenase-2 and matrix metalloproteinase-9 in human articular chondrocytes: Implications for the treatment of osteoarthritis
  343. Expression and nephron segment-specific distribution of major renal aquaporins (AQP1-4) in Equus caballus, the domestic horse
  344. Evidence for functional ATP-sensitive (KATP) potassium channels in human and equine articular chondrocytes
  345. Hypoxic Regulation of Glucose Transport, Anaerobic Metabolism and Angiogenesis in Cancer: Novel Pathways and Targets for Anticancer Therapeutics
  346. Resveratrol Inhibits IL‐1β–Induced Stimulation of Caspase‐3 and Cleavage of PARP in Human Articular Chondrocytes in Vitro
  347. Distribution of the AQP4 Water Channel in Normal Human Tissues: Protein and Tissue Microarrays Reveal Expression in Several New Anatomical Locations, including the Prostate Gland and Seminal Vesicles
  348. Regulation of 2‐Deoxy‐d‐Glucose Transport, Lactate Metabolism, and MMP‐2 Secretion by the Hypoxia Mimetic Cobalt Chloride in Articular Chondrocytes
  349. Igf-I extends the chondrogenic potential of human articular chondrocytes in vitro: Molecular association between Sox9 and Erk1/2
  350. A new low temperature method for high yield isolation of chondrocytes from elderly human subjects and its applicability to mature articular cartilage from older animals
  351. Glucose Sensing in Chondrocytes via GLUT1 and GLUT3: Implications for Articular Cartilage and Intervertebral Disc Metabolism
  352. P172 CURCUMIN AND RESVERATROL REDUCE LIPOPOLYSACCHARIDE MEDIATED GLYCOSAMINOGLYCAN RELEASE IN AN EXPLANT MODEL OF CANINE ARTICULAR CARTILAGE
  353. P179 GLUCOSE TRANSPORT IN IMMORTALIZED HUMAN CHONDROCYTES (C-28/I2) IN NORMOXIA AND HYPOXIA
  354. A hypothesis for the origin and pathogenesis of rheumatoid diseases
  355. Curcumin protects human chondrocytes from IL-1β-induced inhibition of collagen type II and β1-integrin expression and activation of caspase-3: An immunomorphological study
  356. Heterogeneous expression of the aquaporin 1 (AQP1) water channel in tumors of the prostate, breast, ovary, colon and lung: A study using high density multiple human tumor tissue microarrays
  357. Expression of the GLUT1 and GLUT9 facilitative glucose transporters in embryonic chondroblasts and mature chondrocytes in ovine articular cartilage
  358. Nutraceutical Therapies for Degenerative Joint Diseases: A Critical Review
  359. Quantitative analysis of voltage-gated potassium currents from primary equine (Equus caballus) and elephant (Loxodonta africana) articular chondrocytes
  360. Differential regulation of the GLUT1 and GLUT3 glucose transporters by growth factors and pro-inflammatory cytokines in equine articular chondrocytes
  361. Distribution of AQP2 and AQP3 water channels in human tissue microarrays
  362. Vimentin-Positive, c-KIT-Negative Interstitial Cells in Human and Rat Uterus: A Role in Pacemaking?1
  363. Effects of Curcumin (Diferuloylmethane) on Nuclear Factor κB Signaling in Interleukin‐1β‐Stimulated Chondrocytes
  364. Aquaporin water channels AQP1 and AQP3, are expressed in equine articular chondrocytes
  365. Cultivation of human tenocytes in high-density culture
  366. Immunohistochemical localization of aquaporin�10 in the apical membranes of the human ileum: a potential pathway for luminal water and small solute absorption
  367. Loss of chondrogenic potential in dedifferentiated chondrocytes correlates with deficient Shc–Erk interaction and apoptosis
  368. Chronic equine laminitis is characterised by loss of GLUT1, GLUT4 and ENaC positive laminar keratinocytes
  369. Expression of the AQP-1 water channel in normal human tissues: a semiquantitative study using tissue microarray technology
  370. Regeneration influences expression of the Na+,K+-atpase subunit isoforms in the rat peripheral nervous system
  371. Expression and cellular localization of Na,K‐ATPase isoforms in the rat ventral prostate
  372. Apoptosis and the loss of chondrocyte survival signals contribute to articular cartilage degradation in osteoarthritis
  373. Expression of the VEGF receptor-3 in osteoarthritic chondrocytes: stimulation by interleukin-1? and association with ?1-integrins
  374. Chondrocyte apoptosis, inflammatory mediators and equine osteoarthritis
  375. Expression and Cellular Localization of Na,K‐ATPase Isoforms in Dog Prostate in Health and Disease
  376. Na,K‐ATPase Isoforms in Pregnant and Nonpregnant Rat Uterus
  377. Molecular characterization and partial cDNA cloning of facilitative glucose transporters expressed in human articular chondrocytes; stimulation of 2-deoxyglucose uptake by IGF-I and elevated MMP-2 secretion by glucose deprivation
  378. ATPase pumps in osteoclasts and osteoblasts
  379. HUMAN ARTICULAR CHONDROCYTES EXPRESS THREE FACILITATIVE GLUCOSE TRANSPORTER ISOFORMS: GLUT1, GLUT3 AND GLUT9
  380. Role of chondrocyte death and hypocellularity in ageing human articular cartilage and the pathogenesis of osteoarthritis
  381. INTEGRINS AND STRETCH ACTIVATED ION CHANNELS; PUTATIVE COMPONENTS OF FUNCTIONAL CELL SURFACE MECHANORECEPTORS IN ARTICULAR CHONDROCYTES
  382. Role of extensin peroxidase in tomato ( Lycopersicon esculentum Mill.) seedling growth
  383. Progress in neuropharmacology and neurotoxicology of pesticides and drugs. Edited by DJ Beadle, The Royal Society of Chemistry, Cambridge, 1999 ISBN 0 85404 729 8
  384. Epithelial sodium channels in skeletal cells; a role in mechanotransduction?
  385. Molecular Aspects of Cell Wall Modifications during Fruit Ripening
  386. EXPRESSION OF CATION EXCHANGER NHE AND ANION EXCHANGER AE ISOFORMS IN PRIMARY HUMAN BONE‐DERIVED OSTEOBLASTS
  387. Inhibition of Na+, K+-ATPase activates swelling-induced taurine efflux in a human neuroblastoma cell line
  388. CHARACTERIZATION OF THE Na+K+‐ATPase IN ISOLATED BOVINE ARTICULAR CHONDROCYTES; MOLECULAR EVIDENCE FOR MULTIPLE α AND β ISOFORMS
  389. Immunologic and autoradiographic localisation of the Na+, K+-ATPase in articular cartilage: Upregulation in response to changes in extracellular Na+ concentration
  390. Potassium Ion Channels in Articular Chondrocytes
  391. Regeneration of Articular Cartilage
  392. Faculty of 1000 evaluation for Sleep disturbance in osteoarthritis: linkages with pain, disability, and depressive symptoms.
  393. Faculty of 1000 evaluation for Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage.
  394. Faculty of 1000 evaluation for An investigation of the false discovery rate and the misinterpretation of p-values.
  395. Faculty of 1000 evaluation for The chondrocyte clock gene Bmal1 controls cartilage homeostasis and integrity.