All Stories

  1. Tumor-associated macrophage, angiogenesis and lymphangiogenesis markers predict prognosis of non-small cell lung cancer patients

    Article • Journal of Translational Medicine, November 2020, Springer Science + Business Media

    Dr Stephen M Hewitt

  2. Prognostic implication of SOX2 expression in small intestinal adenocarcinoma

    Article • Virchows Archiv, October 2020, Springer Science + Business Media

    Dr Stephen M Hewitt

  3. The Challenges of Optimizing Biomarkers to Guide Clinical Decision Making

    Article • JNCI Journal of the National Cancer Institute, March 2020, Oxford University Press (OUP)

    Dr Stephen M Hewitt

  4. Tofacitinib enhances delivery of antibody-based therapeutics to tumor cells through modulation of inflammatory cells

    Article • JCI Insight, February 2019, American Society for Clinical Investigation

    Dr Stephen M Hewitt

  5. Histomorphological and Molecular Assessments of the Fixation Times Comparing Formalin and Ethanol-Based Fixatives

    Article • Journal of Histochemistry & Cytochemistry, November 2017, SAGE Publications

    Dr Stephen M Hewitt

  6. Assessing Tumor-Infiltrating Lymphocytes in Solid Tumors

    Article • Advances in Anatomic Pathology, November 2017, Wolters Kluwer Health

    Dr Stephen M Hewitt

  7. Societal challenges of precision medicine: Bringing order to chaos

    Article • European Journal of Cancer, October 2017, Elsevier

    Dr Stephen M Hewitt

  8. Update on tumor-infiltrating lymphocytes (TILs) in breast cancer, including recommendations to assess TILs in residual disease after neoadjuvant therapy and in carcinoma in situ: A report of the International Immuno-Oncology Biomarker Working Group on ...

    Article • Seminars in Cancer Biology, October 2017, Elsevier

    Dr Stephen M Hewitt

  9. Bcl-2-like Protein 11 (BIM) Expression Is Associated with Favorable Prognosis for Patients with Cervical Cancer

    Article • Anticancer Research, September 2017, International Institute of Anticancer Research

    Dr Stephen M Hewitt

  10. Assessing Tumor-infiltrating Lymphocytes in Solid Tumors

    Article • Advances in Anatomic Pathology, September 2017, Wolters Kluwer Health

    Dr Stephen M Hewitt

  11. The anti-cancer effects of itraconazole in epithelial ovarian cancer

    Article • Scientific Reports, July 2017, Nature

    Dr Stephen M Hewitt

  12. Therapeutically targeting glypican-2 via single-domain antibody-based chimeric antigen receptors and immunotoxins in neuroblastoma

    Article • Proceedings of the National Academy of Sciences, July 2017, Proceedings of the National Academy of Sciences

    Dr Stephen M Hewitt

  13. Expression of the scaffold connector enhancer of kinase suppressor of Ras 1 (CNKSR1) is correlated with clinical outcome in pancreatic cancer

    Article • BMC Cancer, July 2017, Springer Science + Business Media

    Dr Stephen M Hewitt

  14. HDAC1 Upregulation by NANOG Promotes Multidrug Resistance and a Stem-like Phenotype in Immune Edited Tumor Cells

    Article • Cancer Research, July 2017, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt

  15. Common Molecular Subtypes Among Asian Hepatocellular Carcinoma and Cholangiocarcinoma

    Article • Cancer Cell, July 2017, Elsevier

    Dr Stephen M Hewitt

  16. The Impact Factor Is a 20th-Century Relic in an Electronic Journal World of Instant Citation Counts

    Article • Journal of Histochemistry & Cytochemistry, June 2017, SAGE Publications

    Dr Stephen M Hewitt

  17. Synaptonemal complex protein 3 is associated with lymphangiogenesis in non-small cell lung cancer patients with lymph node metastasis

    Article • Journal of Translational Medicine, June 2017, Springer Science + Business Media

    Dr Stephen M Hewitt

  18. Discovery and validation of candidate host DNA methylation markers for detection of cervical precancer and cancer

    Article • International Journal of Cancer, May 2017, Wiley

    Dr Stephen M Hewitt

  19. Multiview boosting digital pathology analysis of prostate cancer

    Article • Computer Methods and Programs in Biomedicine, April 2017, Elsevier

    Dr Stephen M Hewitt

  20. Formulation and pH of the Buffered Ethanol Fixative BE70

    Article • Journal of Histochemistry & Cytochemistry, March 2017, SAGE Publications

    Dr Stephen M Hewitt

  21. Editor’s Note

    Article • Journal of Histochemistry & Cytochemistry, March 2017, SAGE Publications

    Dr Stephen M Hewitt

  22. Computational analysis of the mesenchymal signature landscape in gliomas

    Article • BMC Medical Genomics, March 2017, Springer Science + Business Media

    Dr Stephen M Hewitt

  23. Progesterone Receptor Isoform Ratio: A Breast Cancer Prognostic and Predictive Factor for Antiprogestin Responsiveness

    Article • JNCI Journal of the National Cancer Institute, March 2017, Oxford University Press (OUP)

    Dr Stephen M Hewitt

  24. Lumen-based detection of prostate cancer via convolutional neural networks

    Article • March 2017, SPIE

    Dr Stephen M Hewitt

  25. PAX3-FOXO1 is essential for tumour initiation and maintenance but not recurrence in a human myoblast model of rhabdomyosarcoma

    Article • The Journal of Pathology, March 2017, Wiley

    Dr Stephen M Hewitt

  26. Interstitial fibrosis scored on whole-slide digital imaging of kidney biopsies is a predictor of outcome in proteinuric glomerulopathies

    Article • Nephrology Dialysis Transplantation, February 2017, Oxford University Press (OUP)

    Dr Stephen M Hewitt

  27. Digital pathology imaging as a novel platform for standardization and globalization of quantitative nephropathology

    Article • Clinical Kidney Journal, February 2017, Oxford University Press (OUP)

    Dr Stephen M Hewitt

  28. Relationship between crown-like structures and sex-steroid hormones in breast adipose tissue and serum among postmenopausal breast cancer patients

    Article • January 2017, Springer Science + Business Media

    Dr Stephen M Hewitt

  29. API5 confers cancer stem cell-like properties through the FGF2-NANOG axis

    Article • Oncogenesis, January 2017, Nature

    Dr Stephen M Hewitt

  30. Nuclear Architecture Analysis of Prostate Cancer via Convolutional Neural Networks

    Article • IEEE Access, January 2017, Institute of Electrical & Electronics Engineers (IEEE)

    Dr Stephen M Hewitt

  31. Factors contributing to delays in diagnosis of breast cancers in Ghana, West Africa

    Article • Breast Cancer Research and Treatment, December 2016, Springer Science + Business Media

    Dr Stephen M Hewitt

  32. Association between breast cancer genetic susceptibility variants and terminal duct lobular unit involution of the breast

    Article • International Journal of Cancer, November 2016, Wiley

    Dr Stephen M Hewitt, Dr Hannah Oh

  33. Molecular Chaperone HSP90 Is Necessary to Prevent Cellular Senescence via Lysosomal Degradation of p14ARF

    Article • Cancer Research, October 2016, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt

  34. Reduced expression of FILIP1L, a novel WNT pathway inhibitor, is associated with poor survival, progression and chemoresistance in ovarian cancer

    Article • Oncotarget, October 2016, Impact Journals, LLC

    Dr Stephen M Hewitt

  35. Prognostic value of automated KI67 scoring in breast cancer: a centralised evaluation of 8088 patients from 10 study groups

    Article • October 2016, Springer Science + Business Media

    Dr Stephen M Hewitt

  36. Relationships between mammographic density, tissue microvessel density, and breast biopsy diagnosis

    Article • August 2016, Springer Science + Business Media

    Dr Stephen M Hewitt

  37. A melanin-bleaching methodology for molecular and histopathological analysis of formalin-fixed paraffin-embedded tissue

    Article • Laboratory Investigation, August 2016, Nature

    Dr Stephen M Hewitt

  38. Standardized measures of lobular involution and subsequent breast cancer risk among women with benign breast disease: a nested case–control study

    Article • Breast Cancer Research and Treatment, August 2016, Springer Science + Business Media

    Dr Stephen M Hewitt

  39. Prognostic significance of annexin A2 and annexin A4 expression in patients with cervical cancer

    Article • BMC Cancer, July 2016, Springer Science + Business Media

    Dr Stephen M Hewitt

  40. A Buffered Alcohol-Based Fixative for Histomorphologic and Molecular Applications

    Article • Journal of Histochemistry & Cytochemistry, July 2016, Journal of Histochemistry & Cytochemistry (The Histochemical Society)

    Dr Stephen M Hewitt

  41. Ages at menarche- and menopause-related genetic variants in relation to terminal duct lobular unit involution in normal breast tissue

    Article • Breast Cancer Research and Treatment, June 2016, Springer Science + Business Media

    Dr Hannah Oh, Dr Stephen M Hewitt

  42. The Application of Digital Pathology to Improve Accuracy in Glomerular Enumeration in Renal Biopsies

    Article • PLoS ONE, June 2016, PLOS

    Dr Stephen M Hewitt

  43. Morphometry Predicts Early GFR Change in Primary Proteinuric Glomerulopathies: A Longitudinal Cohort Study Using Generalized Estimating Equations

    Article • PLoS ONE, June 2016, PLOS

    Dr Stephen M Hewitt

  44. Automated prostate tissue referencing for cancer detection and diagnosis

    Article • BMC Bioinformatics, June 2016, Springer Science + Business Media

    Dr Stephen M Hewitt

  45. Expression of fibroblast growth factor receptor family members is associated with prognosis in early stage cervical cancer patients

    Article • Journal of Translational Medicine, May 2016, Springer Science + Business Media

    Dr Stephen M Hewitt

  46. Relation of Serum Estrogen Metabolites with Terminal Duct Lobular Unit Involution Among Women Undergoing Diagnostic Image-Guided Breast Biopsy

    Article • Hormones and Cancer, May 2016, Springer Science + Business Media

    Dr Stephen M Hewitt, Dr Hannah Oh

  47. The paraffin-embedded RNA metric (PERM) for RNA isolated from formalin-fixed, paraffin-embedded tissue

    Article • BioTechniques, May 2016, Informa UK (Informa Life Sciences)

    Dr Stephen M Hewitt

  48. Reproducibility of the NEPTUNE descriptor-based scoring system on whole-slide images and histologic and ultrastructural digital images

    Article • Modern Pathology, April 2016, Nature

    Dr Anthony Chang, Dr Stephen M Hewitt

  49. Targeting a Cancer-Specific Epitope of the Epidermal Growth Factor Receptor in Triple-Negative Breast Cancer

    Article • JNCI Journal of the National Cancer Institute, April 2016, Oxford University Press (OUP)

    Dr Stephen M Hewitt

  50. Reproducibility: It Is Just Good Science

    Article • Journal of Histochemistry & Cytochemistry, March 2016, Journal of Histochemistry & Cytochemistry (The Histochemical Society)

    Dr Stephen M Hewitt

  51. Circulating insulin-like growth factor-I, insulin-like growth factor binding protein-3 and terminal duct lobular unit involution of the breast: a cross-sectional study of women with benign breast disease

    Article • February 2016, Springer Science + Business Media

    Dr Stephen M Hewitt

  52. The TRAIL receptor agonist drozitumab targets basal B triple-negative breast cancer cells that express vimentin and Axl

    Article • Breast Cancer Research and Treatment, January 2016, Springer Science + Business Media

    Dr Stephen M Hewitt

  53. Time Advances, People and Language Change, but the Fundamentals Remain the Same

    Article • Journal of Histochemistry & Cytochemistry, December 2015, Journal of Histochemistry & Cytochemistry (The Histochemical Society)

    Dr Stephen M Hewitt

  54. Baseline and early outcomes in glomerular disease patients

    Article • Clinical Journal of the American Society of Nephrology, December 2015, American Society of Nephrology

    MD richard lafayette, Katherine R Tuttle, Dr Fernando Fervenza, Dr Michelle Hladunewich, Dr Marva Moxey-Mims, Dr Alicia M Neu, Crystal A Gadegbeku, Dr Howard Trachtman, Dr Stephen M Hewitt, Jeffrey Kopp, John Lieske

  55. Relationship of Terminal Duct Lobular Unit Involution of the Breast with Area and Volume Mammographic Densities

    Article • Cancer Prevention Research, December 2015, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt, Dr Hannah Oh

  56. Clinical significance of OCT4 and SOX2 protein expression in cervical cancer

    Article • BMC Cancer, December 2015, Springer Science + Business Media

    Dr Stephen M Hewitt

  57. Efficacy of Intralesional Botulinum Toxin A for Treatment of Painful Cutaneous Leiomyomas

    Article • JAMA Dermatology, October 2015, American Medical Association (AMA)

    Dr Stephen M Hewitt

  58. A Novel Quantitative Multiplex Tissue Immunoblotting for Biomarkers Predicts a Prostate Cancer Aggressive Phenotype

    Article • Cancer Epidemiology Biomarkers & Prevention, September 2015, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt

  59. Modification of Occupational Exposures on Bladder Cancer Risk by Common Genetic Polymorphisms

    Article • JNCI Journal of the National Cancer Institute, September 2015, Oxford University Press (OUP)

    Dr Stephen M Hewitt

  60. PI3K/AKT activation induces PTEN ubiquitination and destabilization accelerating tumourigenesis

    Article • Nature Communications, July 2015, Nature

    Dr Stephen M Hewitt

  61. Molecular transitions from papillomavirus infection to cervical precancer and cancer: Role of stromal estrogen receptor signaling

    Article • Proceedings of the National Academy of Sciences, June 2015, Proceedings of the National Academy of Sciences

    Dr Stephen M Hewitt

  62. Pancreatic adenocarcinoma up-regulated factor expression is associated with disease-specific survival in cervical cancer patients

    Article • Human Pathology, June 2015, Elsevier

    Dr Stephen M Hewitt

  63. Assessment of a panel of tumor markers for the differential diagnosis of benign and malignant effusions by well-based reverse phase protein array

    Article • Diagnostic Pathology, May 2015, Springer Science + Business Media

    Dr Stephen M Hewitt

  64. A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis

    Article • Nature Genetics, May 2015, Nature

    Dr Stephen M Hewitt

  65. Morphology in the Digital Age: Integrating High-Resolution Description of Structural Alterations With Phenotypes and Genotypes

    Article • Seminars in Nephrology, May 2015, Elsevier

    Dr Stephen M Hewitt

  66. Expression of Stanniocalcin 1 in Thyroid Side Population Cells and Thyroid Cancer Cells

    Article • Thyroid, April 2015, Mary Ann Liebert Inc

    Dr Stephen M Hewitt

  67. CDK4 Amplification Reduces Sensitivity to CDK4/6 Inhibition in Fusion-Positive Rhabdomyosarcoma

    Article • Clinical Cancer Research, March 2015, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt

  68. Nucleus detection using gradient orientation information and linear least squares regression

    Article • March 2015, SPIE

    Dr Stephen M Hewitt

  69. Uncertainty in the assessment of immunohistochemical staining with optical and digital microscopy: lessons from a reader study

    Article • March 2015, SPIE

    Dr Stephen M Hewitt

  70. Risk of follicular lymphoma associated withBCL2translocations in peripheral blood

    Article • Leukemia & Lymphoma, March 2015, Taylor & Francis

    Dr Stephen M Hewitt

  71. Cross-Disciplinary Biomarkers Research: Lessons Learned by the CKD Biomarkers Consortium

    Article • Clinical Journal of the American Society of Nephrology, March 2015, American Society of Nephrology

    Dr Stephen M Hewitt, Chi-yuan Hsu, Brad Rovin, PhD Ilse Daehn Daehn

  72. Cell-Cycle Protein Expression in a Population-Based Study of Ovarian and Endometrial Cancers

    Article • Frontiers in Oncology, February 2015, Frontiers

    Dr Stephen M Hewitt

  73. The Evolution of Pre-analytic Factors in Anatomic Pathology

    Article • January 2015, Springer Science + Business Media

    Dr Stephen M Hewitt

  74. Proteomic Expressional Profiling of a Paraffin-Embedded Tissue by Multiplex Tissue Immunoblotting

    Article • January 2015, Springer Science + Business Media

    Dr Stephen M Hewitt

  75. Prognostic Significance of AMP-Dependent Kinase Alpha Expression in Cervical Cancer

    Article • Pathobiology, January 2015, Karger Publishers

    Dr Stephen M Hewitt

  76. A Well-Based Reverse-Phase Protein Array of Formalin-Fixed Paraffin-Embedded Tissue

    Article • January 2015, Springer Science + Business Media

    Dr Stephen M Hewitt

  77. Tissue Microarray

    Article • January 2015, Springer Science + Business Media

    Dr Stephen M Hewitt

  78. Greater absolute risk for all subtypes of breast cancer in the US than Malaysia

    Article • Breast Cancer Research and Treatment, December 2014, Springer Science + Business Media

    Dr Stephen M Hewitt

  79. Circulating Sex Hormones and Terminal Duct Lobular Unit Involution of the Normal Breast

    Article • Cancer Epidemiology Biomarkers & Prevention, December 2014, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt

  80. Evaluation environment for digital and analog pathology: a platform for validation studies

    Article • Journal of Medical Imaging, November 2014, SPIE

    Dr Stephen M Hewitt

  81. The 19q12 Bladder Cancer GWAS Signal: Association with Cyclin E Function and Aggressive Disease

    Article • Cancer Research, October 2014, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt

  82. Improving the State of the Science of Immunohistochemistry

    Article • Journal of Histochemistry & Cytochemistry, October 2014, Journal of Histochemistry & Cytochemistry (The Histochemical Society)

    Dr Stephen M Hewitt

  83. Controls for Immunohistochemistry

    Article • Journal of Histochemistry & Cytochemistry, October 2014, Journal of Histochemistry & Cytochemistry (The Histochemical Society)

    Dr Stephen M Hewitt

  84. Terminal Duct Lobular Unit Involution of the Normal Breast: Implications for Breast Cancer Etiology

    Article • JNCI Journal of the National Cancer Institute, October 2014, Oxford University Press (OUP)

    Dr Stephen M Hewitt

  85. microRNA Alterations Driving Acute and Late Stages of Radiation-Induced Fibrosis in a Murine Skin Model

    Article • International Journal of Radiation Oncology*Biology*Physics, September 2014, Elsevier

    Dr Stephen M Hewitt

  86. Brightfield Proximity Ligation Assay Reveals Both Canonical and Mixed Transforming Growth Factor- /Bone Morphogenetic Protein Smad Signaling Complexes in Tissue Sections

    Article • Journal of Histochemistry & Cytochemistry, August 2014, Journal of Histochemistry & Cytochemistry (The Histochemical Society)

    Dr Stephen M Hewitt

  87. Consistency and Standardization of Color in Medical Imaging: a Consensus Report

    Article • Journal of Digital Imaging, July 2014, Springer Science + Business Media

    Dr Stephen M Hewitt

  88. Endogenous intrahepatic IFNs and association with IFN-free HCV treatment outcome

    Article • Journal of Clinical Investigation, July 2014, American Society for Clinical Investigation

    Dr Stephen M Hewitt

  89. AR-Regulated TWEAK-FN14 Pathway Promotes Prostate Cancer Bone Metastasis

    Article • Cancer Research, June 2014, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt

  90. Synaptonemal Complex Protein 3 Is a Prognostic Marker in Cervical Cancer

    Article • PLoS ONE, June 2014, PLOS

    Dr Stephen M Hewitt

  91. PLCE1 mRNA and Protein Expression and Survival of Patients with Esophageal Squamous Cell Carcinoma and Gastric Adenocarcinoma

    Article • Cancer Epidemiology Biomarkers & Prevention, May 2014, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt

  92. Profiling of Phospho-AKT, Phospho-mTOR, Phospho-MAPK and EGFR in Non-small Cell Lung Cancer

    Article • Journal of Histochemistry & Cytochemistry, May 2014, Journal of Histochemistry & Cytochemistry (The Histochemical Society)

    Dr Stephen M Hewitt

  93. CLPTM1L Promotes Growth and Enhances Aneuploidy in Pancreatic Cancer Cells

    Article • Cancer Research, March 2014, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt

  94. Profound Prevention of Experimental Brain Metastases of Breast Cancer by Temozolomide in an MGMT-Dependent Manner

    Article • Clinical Cancer Research, March 2014, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt

  95. eeDAP: An evaluation environment for digital and analog pathology

    Article • March 2014, SPIE

    Dr Stephen M Hewitt

  96. Expression of stress-induced phosphoprotein1 (STIP1) is associated with tumor progression and poor prognosis in epithelial ovarian cancer

    Article • Genes Chromosomes and Cancer, February 2014, Wiley

    Dr Stephen M Hewitt

  97. Multiplex Quantitative Measurement of mRNAs From Fixed Tissue Microarray Sections

    Article • Applied Immunohistochemistry & Molecular Morphology, January 2014, Wolters Kluwer Health

    Professor Elisabeth Smela, Dr Stephen M Hewitt

  98. Observer Performance in the Use of Digital and Optical Microscopy for the Interpretation of Tissue-Based Biomarkers

    Article • Analytical Cellular Pathology, January 2014, Hindawi Publishing Corporation

    Dr Stephen M Hewitt

  99. MICA/B and ULBP1 NKG2D ligands are independent predictors of good prognosis in cervical cancer

    Article • BMC Cancer, January 2014, Springer Science + Business Media

    Dr Stephen M Hewitt

  100. HER-2 assessment in formalin-fixed paraffin-embedded breast cancer tissue by well-based reverse phase protein array

    Article • Clinical Proteomics, January 2014, Springer Science + Business Media

    Dr Stephen M Hewitt

  101. Assessment of vascular endothelial growth factor in formalin fixed, paraffin embedded colon cancer specimens by means of a well-based reverse phase protein array

    Article • Proteome Science, January 2014, Springer Science + Business Media

    Dr Stephen M Hewitt

  102. Apoptosis inhibitor-5 overexpression is associated with tumor progression and poor prognosis in patients with cervical cancer

    Article • BMC Cancer, January 2014, Springer Science + Business Media

    Dr Stephen M Hewitt

  103. Multiple chimeric antigen receptors successfully target chondroitin sulfate proteoglycan 4 in several different cancer histologies and cancer stem cells

    Article • Journal for ImmunoTherapy of Cancer, January 2014, Springer Science + Business Media

    Dr Stephen M Hewitt

  104. Characterization of NADPH oxidase 5 expression in human tumors and tumor cell lines with a novel mouse monoclonal antibody

    Article • Free Radical Biology and Medicine, December 2013, Elsevier

    Dr Stephen M Hewitt

  105. Breast cancer susceptibility risk associations and heterogeneity by E-cadherin tumor tissue expression

    Article • Breast Cancer Research and Treatment, November 2013, Springer Science + Business Media

    Dr Stephen M Hewitt

  106. CD44 is prognostic for overall survival in the NCI randomized trial on breast conservation with 25 year follow-up

    Article • Breast Cancer Research and Treatment, November 2013, Springer Science + Business Media

    Dr Stephen M Hewitt

  107. Sporadic naturally occurring melanoma in dogs as a preclinical model for human melanoma

    Article • Pigment Cell & Melanoma Research, November 2013, Wiley

    Dr Stephen M Hewitt

  108. Regulation of accumulation and function of myeloid derived suppressor cells in different murine models of hepatocellular carcinoma

    Article • Journal of Hepatology, November 2013, Elsevier

    Dr Stephen M Hewitt

  109. Application of Selected Reaction Monitoring for Multiplex Quantification of Clinically Validated Biomarkers in Formalin-Fixed, Paraffin-Embedded Tumor Tissue

    Article • Journal of Molecular Diagnostics, July 2013, Elsevier

    Dr Stephen M Hewitt

  110. Improved survival of gastric cancer with tumour Epstein–Barr virus positivity: an international pooled analysis

    Article • Gut, April 2013, BMJ

    Dr Stephen M Hewitt, Dr. Roberto Herrera-Goepfert

  111. Synaptonemal complex protein 3 as a novel prognostic marker in early stage non–small cell lung cancer

    Article • Human Pathology, April 2013, Elsevier

    Professor Junya Fukuoka, Dr Stephen M Hewitt

  112. Design of the Nephrotic Syndrome Study Network (NEPTUNE) to evaluate primary glomerular nephropathy by a multidisciplinary approach

    Article • Kidney International, April 2013, Elsevier

    Dr Stephen M Hewitt, Crystal A Gadegbeku

  113. Quantitative analysis of TDLUs using adaptive morphological shape techniques

    Article • March 2013, SPIE

    Dr Stephen M Hewitt

  114. Erratum: Gene expression and epigenetic discovery screen reveal methylation of SFRP2 in prostate cancer

    Article • International Journal of Cancer, March 2013, Wiley

    Dr Stephen M Hewitt

  115. Follicular Lymphomas in Children and Young Adults

    Article • The American Journal of Surgical Pathology, March 2013, Wolters Kluwer Health

    Dr Stephen M Hewitt

  116. Functional activity and tumor-specific expression of dual oxidase 2 in pancreatic cancer cells and human malignancies characterized with a novel monoclonal antibody

    Article • International Journal of Oncology, February 2013, Spandidos Publications

    Dr Stephen M Hewitt

  117. Digital Pathology Evaluation in the Multicenter Nephrotic Syndrome Study Network (NEPTUNE)

    Article • Clinical Journal of the American Society of Nephrology, February 2013, American Society of Nephrology

    Dr Stephen M Hewitt, Jeffrey Kopp, Sanjeev Sethi

  118. Loss-of-function screen in rhabdomyosarcoma identifies CRKL-YES as a critical signal for tumor growth

    Article • Oncogene, January 2013, Nature

    Dr Stephen M Hewitt

  119. ORIGINAL ARTICLEExpression Analysis of p16, c-Myc, and mSin3A in Non-small Cell Lung Cancer by Computer Aided Scoring and Analysis (CASA)

    Article • Clinical Laboratory, January 2013, Clinical Laboratory Publications

    Dr Stephen M Hewitt

  120. The influence of DNA repair on neurological degeneration, cachexia, skin cancer and internal neoplasms: autopsy report of four xeroderma pigmentosum patients (XP-A, XP-C and XP-D)

    Article • Acta Neuropathologica Communications, January 2013, Springer Science + Business Media

    Dr Stephen M Hewitt

  121. Prognostic assessment of hypoxia and metabolic markers in cervical cancer using automated digital image analysis of immunohistochemistry

    Article • Journal of Translational Medicine, January 2013, Springer Science + Business Media

    Dr Stephen M Hewitt

  122. Estrogen receptor and progesterone receptor expression in normal terminal duct lobular units surrounding invasive breast cancer

    Article • Breast Cancer Research and Treatment, December 2012, Springer Science + Business Media

    Dr Stephen M Hewitt

  123. Genetic Variant as a Selection Marker for Anti-Prostate Stem Cell Antigen Immunotherapy of Bladder Cancer

    Article • JNCI Journal of the National Cancer Institute, December 2012, Oxford University Press (OUP)

    Dr Stephen M Hewitt

  124. Targeting Tumor-Infiltrating Macrophages Decreases Tumor-Initiating Cells, Relieves Immunosuppression, and Improves Chemotherapeutic Responses

    Article • Cancer Research, December 2012, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt

  125. Nanog signaling in cancer promotes stem-like phenotype and immune evasion

    Article • Journal of Clinical Investigation, October 2012, American Society for Clinical Investigation

    Dr Stephen M Hewitt

  126. HER3 overexpression is a prognostic indicator of extrahepatic cholangiocarcinoma

    Article • Virchows Archiv, October 2012, Springer Science + Business Media

    Dr Stephen M Hewitt

  127. A crypticBAP1splice mutation in a family with uveal and cutaneous melanoma, and paraganglioma

    Article • Pigment Cell & Melanoma Research, October 2012, Wiley

    Dr Stephen M Hewitt

  128. Gene expression and epigenetic discovery screen reveal methylation of SFRP2 in prostate cancer

    Article • International Journal of Cancer, September 2012, Wiley

    Dr Stephen M Hewitt

  129. What Measures Should Biobankers Employ to Prevent Possible Glitches in Storage Technology?

    Article • Biopreservation and Biobanking, August 2012, Mary Ann Liebert Inc

    Dr Stephen M Hewitt

  130. Evaluation of Lymphangiogenic Factors, Vascular Endothelial Growth Factor D and E-Cadherin in Distinguishing Inflammatory From Locally Advanced Breast Cancer

    Article • Clinical Breast Cancer, August 2012, Elsevier

    Dr Stephen M Hewitt

  131. Association of prion protein expression with pancreatic adenocarcinoma survival in the SEER residual tissue repository

    Article • Cancer Biomarkers, July 2012, IOS Press

    Dr Stephen M Hewitt

  132. Cell-Cycle Control in Urothelial Carcinoma: Large-scale Tissue Array Analysis of Tumor Tissue from Maine and Vermont

    Article • Cancer Epidemiology Biomarkers & Prevention, July 2012, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt

  133. Expression of heme oxygenase-1 in non-small cell lung cancer (NSCLC) and its correlation with clinical data

    Article • Lung Cancer, July 2012, Elsevier

    Dr Stephen M Hewitt

  134. Genomic copy number alterations in clear cell renal carcinoma: associations with case characteristics and mechanisms of VHL gene inactivation

    Article • Oncogenesis, June 2012, Nature

    Dr Stephen M Hewitt

  135. A pressure cooking-based DNA extraction from archival formalin-fixed, paraffin-embedded tissue

    Article • Analytical Biochemistry, June 2012, Elsevier

    Dr Stephen M Hewitt

  136. Human CCR4+CCR6+Th17 Cells Suppress Autologous CD8+ T Cell Responses

    Article • The Journal of Immunology, May 2012, The American Association of Immunologists

    Dr Stephen M Hewitt

  137. Automatic detection of melanoma progression by histological analysis of secondary sites

    Article • Cytometry Part A, March 2012, Wiley

    Dr Stephen M Hewitt

  138. Leveling the Playing Field: Bringing Development of Biomarkers and Molecular Diagnostics up to the Standards for Drug Development

    Article • Clinical Cancer Research, March 2012, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt

  139. Impact of Preanalytic Factors on the Design and Application of Integral Biomarkers for Directing Patient Therapy

    Article • Clinical Cancer Research, March 2012, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt

  140. mTOR as a Molecular Target in HPV-Associated Oral and Cervical Squamous Carcinomas

    Article • Clinical Cancer Research, March 2012, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt

  141. Analysis of Terminal Duct Lobular Unit (TDLU) Involution in Luminal A and Basal Breast Cancers

    Article • Breast Cancer Research, January 2012, Springer Science + Business Media

    Dr Stephen M Hewitt

  142. Extremely High Tp53 Mutation Load in Esophageal Squamous Cell Carcinoma in Golestan Province, Iran

    Article • PLoS ONE, December 2011, PLOS

    Dr Stephen M Hewitt

  143. The cocaine- and amphetamine-regulated transcript mediates ligand-independent activation of ERα, and is an independent prognostic factor in node-negative breast cancer

    Article • Oncogene, December 2011, Nature

    Dr Stephen M Hewitt

  144. What Are the Most Oppressing Legal and Ethical Issues Facing Biorepositories and What Are Some Strategies to Address Them?

    Article • Biopreservation and Biobanking, December 2011, Mary Ann Liebert Inc

    Dr Stephen M Hewitt

  145. The role of secreted frizzled-related protein 2 expression in prostate cancer

    Article • Histopathology, December 2011, Wiley

    Dr Stephen M Hewitt

  146. 56. Chemical preservation of tissue: Methods and models

    Article • Cryobiology, December 2011, Elsevier

    Dr Stephen M Hewitt

  147. Associated expressions of FGFR-2 and FGFR-3: from mouse mammary gland physiology to human breast cancer

    Article • Breast Cancer Research and Treatment, November 2011, Springer Science + Business Media

    Dr Stephen M Hewitt

  148. Tissue Microarrays as a Tool in the Discovery and Validation of Predictive Biomarkers

    Article • October 2011, Springer Science + Business Media

    Dr Stephen M Hewitt

  149. Evaluation of eIF4E Expression in an Osteosarcoma-Specific Tissue Microarray

    Article • Journal of Pediatric Hematology/Oncology, October 2011, Wolters Kluwer Health

    Dr Stephen M Hewitt

  150. Wilms Tumor-1, Claudin-1 and Ezrin Are Useful Immunohistochemical Markers That Help to Distinguish Schwannoma from Fibroblastic Meningioma

    Article • Pathology & Oncology Research, September 2011, Springer Science + Business Media

    Dr AVNINDER SINGH, Dr Stephen M Hewitt

  151. Paracrine SLPI secretion upregulates MMP-9 transcription and secretion in ovarian cancer cells

    Article • Gynecologic Oncology, September 2011, Elsevier

    Dr Stephen M Hewitt

  152. Gray zone lymphoma: chromosomal aberrations with immunophenotypic and clinical correlations

    Article • Modern Pathology, August 2011, Nature

    Dr Stephen M Hewitt

  153. CLSI Releases Updated Guideline for the Development of Immunohistochemical Assays

    Article • Applied Immunohistochemistry & Molecular Morphology, July 2011, Wolters Kluwer Health

    Dr Stephen M Hewitt

  154. Downregulation of Filamin A Interacting Protein 1-Like is Associated with Promoter Methylation and Induces an Invasive Phenotype in Ovarian Cancer

    Article • Molecular Cancer Research, June 2011, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt, Gloria Huang

  155. Phase IIA Trial Testing Erlotinib as an Intervention against Intraductal Pancreatic Mucinous Neoplasms

    Article • Cancer Prevention Research, April 2011, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt

  156. Methylation profiling of mediastinal gray zone lymphoma reveals a distinctive signature with elements shared by classical Hodgkin's lymphoma and primary mediastinal large B-cell lymphoma

    Article • Haematologica, March 2011, Ferrata Storti Foundation (Haematologica)

    Dr Stephen M Hewitt

  157. Global Gene Expression Profiling and Validation in Esophageal Squamous Cell Carcinoma and Its Association with Clinical Phenotypes

    Article • Clinical Cancer Research, March 2011, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt

  158. An N-terminal truncated carboxypeptidase E splice isoform induces tumor growth and is a biomarker for predicting future metastasis in human cancers

    Article • Journal of Clinical Investigation, March 2011, American Society for Clinical Investigation

    Dr Stephen M Hewitt

  159. Factors Influencing the Degradation of Archival Formalin-Fixed Paraffin-Embedded Tissue Sections

    Article • Journal of Histochemistry & Cytochemistry, February 2011, SAGE Publications

    Dr Stephen M Hewitt

  160. Systematic Proteome Analysis Identifies Transcription Factor YY1 as a Direct Target of miR-34a

    Article • Journal of Proteome Research, February 2011, American Chemical Society (ACS)

    Dr Stephen M Hewitt

  161. Detection of Somatic Mutations by High-Resolution DNA Melting (HRM) Analysis in Multiple Cancers

    Article • PLoS ONE, January 2011, PLOS

    Dr Stephen M Hewitt

  162. Multimodal microscopy for automated histologic analysis of prostate cancer

    Article • BMC Cancer, January 2011, Springer Science + Business Media

    Dr Stephen M Hewitt

  163. Membranous expression of Her3 is associated with a decreased survival in head and neck squamous cell carcinoma

    Article • Journal of Translational Medicine, January 2011, Springer Science + Business Media

    Dr Stephen M Hewitt

  164. Loss of Klotho during melanoma progression leads to increased filamin cleavage, increased Wnt5A expression, and enhanced melanoma cell motility

    Article • Pigment Cell & Melanoma Research, December 2010, Wiley

    Dr Stephen M Hewitt

  165. Modeling metastasis biology and therapy in real time in the mouse lung

    Article • Journal of Clinical Investigation, October 2010, American Society for Clinical Investigation

    Dr Stephen M Hewitt

  166. Modeling metastasis biology and therapy in real time in the mouse lung

    Article • Journal of Clinical Investigation, August 2010, American Society for Clinical Investigation

    Dr Stephen M Hewitt

  167. Multiple Endocrine Neoplasia Type 1 Deletion in Pancreatic α-Cells Leads to Development of Insulinomas in Mice

    Article • Endocrinology, August 2010, Endocrine Society

    Dr Stephen M Hewitt

  168. Immunoguided Laser Assisted Microdissection Techniques for DNA Methylation Analysis of Archival Tissue Specimens

    Article • Journal of Molecular Diagnostics, July 2010, Elsevier

    Dr Stephen M Hewitt

  169. Polycyclic aromatic hydrocarbon exposure in oesophageal tissue and risk of oesophageal squamous cell carcinoma in north-eastern Iran

    Article • Gut, June 2010, BMJ

    Dr Stephen M Hewitt

  170. Characterizations and validations of novel antibodies toward translational research

    Article • PROTEOMICS - CLINICAL APPLICATIONS, June 2010, Wiley

    Dr Stephen M Hewitt

  171. Glucose transporter Glut-1 is detectable in peri-necrotic regions in many human tumor types but not normal tissues: Study using tissue microarrays

    Article • Annals of Anatomy - Anatomischer Anzeiger, May 2010, Elsevier

    Professor Ali Mobasheri, Dr Stephen M Hewitt

  172. Histo-proteomic profiling of formalin-fixed, paraffin-embedded tissue

    Article • Expert Review of Proteomics, April 2010, Taylor & Francis

    Dr Stephen M Hewitt

  173. Molecular Pathology in Epidemiologic Studies: A Primer on Key Considerations

    Article • Cancer Epidemiology Biomarkers & Prevention, March 2010, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt

  174. Assessment of Automated Image Analysis of Breast Cancer Tissue Microarrays for Epidemiologic Studies

    Article • Cancer Epidemiology Biomarkers & Prevention, March 2010, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt, Sean Davis

  175. Microscopic resolution imaging and proteomics correlation at histogeographically identical location: point by point correlation between ex vivo tissue imaging with high field MRI and multiplex tissue immunoblotting for proteomics profiling

    Article • March 2010, SPIE

    Dr Stephen M Hewitt

  176. Analysis of the expression of human tumor antigens in ovarian cancer tissues

    Article • Cancer Biomarkers, February 2010, IOS Press

    Dr Stephen M Hewitt

  177. Global Genomic and Proteomic Analysis Identifies Biological Pathways Related to High-Risk Neuroblastoma

    Article • Journal of Proteome Research, January 2010, American Chemical Society (ACS)

    Dr Stephen M Hewitt

  178. Overexpression of Phospho-eIF4E Is Associated with Survival through AKT Pathway in Non-Small Cell Lung Cancer

    Article • Clinical Cancer Research, December 2009, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt

  179. NRG1 / ERBB3 signaling in melanocyte development and melanoma: inhibition of differentiation and promotion of proliferation

    Article • Pigment Cell & Melanoma Research, December 2009, Wiley

    Dr Stephen M Hewitt

  180. The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma

    Article • Oncogene, October 2009, Nature

    Dr Stephen M Hewitt

  181. Identification of FGFR4-activating mutations in human rhabdomyosarcomas that promote metastasis in xenotransplanted models

    Article • Journal of Clinical Investigation, October 2009, American Society for Clinical Investigation

    Dr Stephen M Hewitt

  182. Cytokeratin Immunoexpression in Esophageal Squamous Cell Carcinoma of High-risk Population in Northeast India

    Article • Applied Immunohistochemistry & Molecular Morphology, October 2009, Wolters Kluwer Health

    Dr AVNINDER SINGH, Dr Stephen M Hewitt

  183. The Chemokine CXCL16 and Its Receptor, CXCR6, as Markers and Promoters of Inflammation-Associated Cancers

    Article • PLoS ONE, August 2009, PLOS

    Dr Stephen M Hewitt

  184. Correlation between clinical outcome and growth factor pathway expression in osteogenic sarcoma

    Article • Cancer, August 2009, Wiley

    Dr Stephen M Hewitt

  185. Automated Quantitative Assessment of HER-2/neu Immunohistochemical Expression in Breast Cancer

    Article • IEEE Transactions on Medical Imaging, June 2009, Institute of Electrical & Electronics Engineers (IEEE)

    Dr Stephen M Hewitt

  186. DEAR1 Is a Dominant Regulator of Acinar Morphogenesis and an Independent Predictor of Local Recurrence-Free Survival in Early-Onset Breast Cancer

    Article • PLoS Medicine, May 2009, PLOS

    Dr Stephen M Hewitt, Khandan Keyomarsi

  187. Molecular profiling to identify molecular mechanism in esophageal cancer with familial clustering

    Article • Oncology Reports, April 2009, Spandidos Publications

    Dr Stephen M Hewitt

  188. Deciphering von Hippel-Lindau (VHL/Vhl)-Associated Pancreatic Manifestations by Inactivating Vhl in Specific Pancreatic Cell Populations

    Article • PLoS ONE, April 2009, PLOS

    Dr Stephen M Hewitt

  189. Associations between Selected Biomarkers and Prognosis in a Population-Based Pancreatic Cancer Tissue Microarray

    Article • Cancer Research, March 2009, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt

  190. Sperm-Derived SPANX-B Is a Clinically Relevant Tumor Antigen That Is Expressed in Human Tumors and Readily Recognized by Human CD4+ and CD8+ T Cells

    Article • Clinical Cancer Research, March 2009, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt

  191. Recapitulation of Pancreatic Neuroendocrine Tumors in Human Multiple Endocrine Neoplasia Type I Syndrome via Pdx1-Directed Inactivation of Men1

    Article • Cancer Research, February 2009, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt

  192. The Expression of Phospho-AKT, Phospho-mTOR, and PTEN in Extrahepatic Cholangiocarcinoma

    Article • Clinical Cancer Research, January 2009, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt

  193. Transfer and Multiplex Immunoblotting of a Paraffin Embedded Tissue

    Article • January 2009, Springer Science + Business Media

    Dr Stephen M Hewitt

  194. Tissue Microarrays as a Tool in the Discovery and Validation of Tumor Markers

    Article • January 2009, Springer Science + Business Media

    Dr Stephen M Hewitt

  195. Canine tumor cross-species genomics uncovers targets linked to osteosarcoma progression

    Article • BMC Genomics, January 2009, Springer Science + Business Media

    Dr Stephen M Hewitt, Sean Davis

  196. Biomarkers of apoptosis and survival in esophageal squamous cell carcinoma

    Article • BMC Cancer, January 2009, Springer Science + Business Media

    Dr Stephen M Hewitt

  197. Tumor vasculature-targeted delivery of tumor necrosis factor-α*

    Article • Cancer, December 2008, Wiley

    Dr Stephen M Hewitt

  198. DNA Methylation Represses IFN- -Induced and Signal Transducer and Activator of Transcription 1-Mediated IFN Regulatory Factor 8 Activation in Colon Carcinoma Cells

    Article • Molecular Cancer Research, December 2008, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt

  199. Wnt5A Regulates Expression of Tumor-Associated Antigens in Melanoma via Changes in Signal Transducers and Activators of Transcription 3 Phosphorylation

    Article • Cancer Research, December 2008, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt

  200. The actin-cytoskeleton linker protein ezrin is regulated during osteosarcoma metastasis by PKC

    Article • Oncogene, December 2008, Nature

    Dr Stephen M Hewitt

  201. Global Histone H4 Acetylation and HDAC2 Expression in Colon Adenoma and Carcinoma

    Article • Digestive Diseases and Sciences, December 2008, Springer Science + Business Media

    Dr Seyed Mehdi Nouraie, Dr Stephen M Hewitt

  202. H. pylori-Induced Apoptosis in Human Gastric Cancer Cells Mediated via the Release of Apoptosis-Inducing Factor from Mitochondria

    Article • Helicobacter, December 2008, Wiley

    Dr Seyed Mehdi Nouraie, Dr Stephen M Hewitt

  203. Consensus Recommendations on Estrogen Receptor Testing in Breast Cancer By Immunohistochemistry

    Article • Applied Immunohistochemistry & Molecular Morphology, December 2008, Wolters Kluwer Health

    Dr Stephen M Hewitt

  204. Recommendations for Collection and Handling of Specimens From Group Breast Cancer Clinical Trials

    Article • Journal of Clinical Oncology, October 2008, American Society of Clinical Oncology (ASCO)

    Dr Stephen M Hewitt

  205. Validation of proteomic-based discovery with tissue microarrays

    Article • PROTEOMICS - CLINICAL APPLICATIONS, October 2008, Wiley

    Dr Stephen M Hewitt

  206. A well-based reverse-phase protein array applicable to extracts from formalin-fixed paraffin-embedded tissue

    Article • PROTEOMICS - CLINICAL APPLICATIONS, October 2008, Wiley

    Dr Stephen M Hewitt

  207. Functional Characterization of Filamin A Interacting Protein 1-Like, a Novel Candidate for Antivascular Cancer Therapy

    Article • Cancer Research, September 2008, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt

  208. Pharmacodynamic Assessment of Histone Deacetylase Inhibitors: Infrared Vibrational Spectroscopic Imaging of Protein Acetylation

    Article • Analytical Chemistry, August 2008, American Chemical Society (ACS)

    Dr Stephen M Hewitt

  209. Expression of the Interferon Regulatory Factor 8/ICSBP-1 in Human Reactive Lymphoid Tissues and B-cell Lymphomas: A Novel Germinal Center Marker

    Article • The American Journal of Surgical Pathology, August 2008, Wolters Kluwer Health

    Dr Stephen M Hewitt

  210. Factors in Tissue Handling and Processing That Impact RNA Obtained From Formalin-fixed, Paraffin-embedded Tissue

    Article • Journal of Histochemistry & Cytochemistry, July 2008, SAGE Publications

    Dr Stephen M Hewitt

  211. Overexpression of CDC25B and LAMC2 mRNA and Protein in Esophageal Squamous Cell Carcinomas and Premalignant Lesions in Subjects from a High-Risk Population in China

    Article • Cancer Epidemiology Biomarkers & Prevention, June 2008, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt

  212. Automated evaluation of HER-2/neu immunohistochemical expression in breast cancer using digital microscopy

    Article • May 2008, Institute of Electrical & Electronics Engineers (IEEE)

    Dr Stephen M Hewitt

  213. Altered Cytoplasmic-to-Nuclear Ratio of Survivin Is a Prognostic Indicator in Breast Cancer

    Article • Clinical Cancer Research, May 2008, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt

  214. Tissue microarray: A simple technology that has revolutionized research in pathology

    Article • Journal of Postgraduate Medicine, January 2008, Medknow

    Dr AVNINDER SINGH, Dr Stephen M Hewitt

  215. Frozen Protein Arrays

    Article • January 2008, Springer Science + Business Media

    Dr Stephen M Hewitt

  216. Aberrant nucleocytoplasmic localization of the retinoblastoma tumor suppressor protein in human cancer correlates with moderate/poor tumor differentiation

    Article • Oncogene, December 2007, Nature

    Dr Stephen M Hewitt

  217. The ubiquitin ligase gp78 promotes sarcoma metastasis by targeting KAI1 for degradation

    Article • Nature Reports Stem Cells, November 2007, Nature

    Dr Stephen M Hewitt

  218. Hormonal Markers in Breast Cancer: Coexpression, Relationship with Pathologic Characteristics, and Risk Factor Associations in a Population-Based Study

    Article • Cancer Research, November 2007, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt

  219. Transactivation of the EGFR by AP-1 Is Induced by Helicobacter pylori in Gastric Cancer

    Article • The American Journal of Gastroenterology, October 2007, Nature

    Dr Stephen M Hewitt

  220. Liver proteomics for therapeutic drug discovery: Inhibition of the cyclophilin receptor CD147 attenuates sepsis-induced acute renal failure*

    Article • Critical Care Medicine, October 2007, Wolters Kluwer Health

    Dr Stephen M Hewitt

  221. Variation in breast cancer hormone receptor andHER2levels by etiologic factors: A population-based analysis

    Article • International Journal of Cancer, September 2007, Wiley

    Dr Stephen M Hewitt

  222. Dissecting the Akt/Mammalian Target of Rapamycin Signaling Network: Emerging Results from the Head and Neck Cancer Tissue Array Initiative

    Article • Clinical Cancer Research, September 2007, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt

  223. Tissue microarrays enabling high-throughput molecular pathology

    Article • Current Opinion in Biotechnology, August 2007, Elsevier

    Dr Stephen M Hewitt

  224. Layered Peptide Array for Multiplex Immunohistochemistry

    Article • Journal of Molecular Diagnostics, July 2007, Elsevier

    Dr Stephen M Hewitt

  225. Recommendations for Improved Standardization of Immunohistochemistry

    Article • Applied Immunohistochemistry & Molecular Morphology, June 2007, Wolters Kluwer Health

    Dr Stephen M Hewitt

  226. Glut-1 as a therapeutic target: increased chemoresistance and HIF-1-independent link with cell turnover is revealed through COMPARE analysis and metabolomic studies

    Article • Cancer Chemotherapy and Pharmacology, May 2007, Springer Science + Business Media

    Dr Stephen M Hewitt

  227. Expression of EIF3-p48/INT6, TID1 and Patched in cancer, a profiling of multiple tumor types and correlation of expression

    Article • Journal of Biomedical Science, March 2007, Springer Science + Business Media

    Dr Stephen M Hewitt

  228. Expression of the cytoskeleton linker protein ezrin in human cancers

    Article • Clinical & Experimental Metastasis, March 2007, Springer Science + Business Media

    Dr CHARLES A POWELL, Dr Stephen M Hewitt

  229. Proteomic expression profiling of thyroid neoplasms

    Article • PROTEOMICS - CLINICAL APPLICATIONS, March 2007, Wiley

    Dr Stephen M Hewitt

  230. Differences in Risk Factors for Breast Cancer Molecular Subtypes in a Population-Based Study

    Article • Cancer Epidemiology Biomarkers & Prevention, March 2007, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt

  231. Desmoglein 3 as a prognostic factor in lung cancer

    Article • Human Pathology, February 2007, Elsevier

    Professor Junya Fukuoka, Dr Stephen M Hewitt

  232. Layered expression scanning: Multiplex molecular analysis of diverse life science platforms

    Article • Clinica Chimica Acta, February 2007, Elsevier

    Dr Stephen M Hewitt

  233. Credentialing Preclinical Pediatric Xenograft Models Using Gene Expression and Tissue Microarray Analysis

    Article • Cancer Research, January 2007, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt

  234. Cell microarray platform for anticancer drug development

    Article • Drug Development Research, January 2007, Wiley

    Dr Stephen M Hewitt

  235. Optimization of Recovery of RNA From Formalin-fixed, Paraffin-embedded Tissue

    Article • Diagnostic Molecular Pathology, December 2006, Wolters Kluwer Health

    Dr Stephen M Hewitt

  236. Markers and Tissue Resources for Melanoma: Meeting Report

    Article • Cancer Research, November 2006, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt

  237. Ezrin mediates growth and survival in Ewing’s sarcoma through the AKT/mTOR, but not the MAPK, signaling pathway

    Article • Clinical & Experimental Metastasis, September 2006, Springer Science + Business Media

    Dr Stephen M Hewitt

  238. Tissue microarrays as a platform for proteomic investigation

    Article • Journal of Molecular Histology, September 2006, Springer Science + Business Media

    Dr Stephen M Hewitt

  239. Construction and Validation of Tissue Microarrays of Ductal Carcinoma In Situ and Terminal Duct Lobular Units Associated With Invasive Breast Carcinoma

    Article • Diagnostic Molecular Pathology, September 2006, Wolters Kluwer Health

    Dr Stephen M Hewitt

  240. Biomarker and drug-target discovery using proteomics in a new rat model of sepsis-induced acute renal failure

    Article • Kidney International, August 2006, Elsevier

    Dr Stephen M Hewitt

  241. High throughput assessment of cells and tissues: Bayesian classification of spectral metrics from infrared vibrational spectroscopic imaging data

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, July 2006, Elsevier

    Dr Stephen M Hewitt

  242. A Multiplex Tissue Immunoblotting Assay for Proteomic Profiling: A Pilot Study of the Normal to Tumor Transition of Esophageal Squamous Cell Carcinoma

    Article • Cancer Epidemiology Biomarkers & Prevention, July 2006, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt

  243. Framework for Parsing, Visualizing and Scoring Tissue Microarray Images

    Article • IEEE Transactions on Information Technology in Biomedicine, April 2006, Institute of Electrical & Electronics Engineers (IEEE)

    Dr Stephen M Hewitt

  244. Intravenously administered vitamin C as cancer therapy: three cases

    Article • Canadian Medical Association Journal, March 2006, Canadian Medical Association (CMA)

    Dr Stephen M Hewitt

  245. Spectrum of activity and molecular correlates of response to phosphatidylinositol ether lipid analogues, novel lipid-based inhibitors of Akt

    Article • Molecular Cancer Therapeutics, March 2006, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt

  246. Sepsis-induced organ failure is mediated by different pathways in the kidney and liver: Acute renal failure is dependent on MyD88 but not renal cell apoptosis

    Article • Kidney International, March 2006, Elsevier

    Dr Stephen M Hewitt

  247. The Role of Interleukin 1 in Growth and Metastasis of Human Cancer Xenografts

    Article • Clinical Cancer Research, February 2006, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt

  248. Tissue microarray analysis of human FRAT1 expression and its correlation with the subcellular localisation of β-catenin in ovarian tumours

    Article • British Journal of Cancer, February 2006, Nature

    Dr Stephen M Hewitt

  249. Transfer and multiplex immunoblotting of a paraffin embedded tissue

    Article • PROTEOMICS, February 2006, Wiley

    Dr Stephen M Hewitt

  250. Antiangiogenic and Antitumor Effects of Bevacizumab in Patients With Inflammatory and Locally Advanced Breast Cancer

    Article • Journal of Clinical Oncology, January 2006, American Society of Clinical Oncology (ASCO)

    Dr Stephen M Hewitt

  251. [20] The Application of Tissue Microarrays in the Validation of Microarray Results

    Article • January 2006, Elsevier

    Dr Stephen M Hewitt

  252. Automated Confocal Imaging and High-Content Screening for Cytomics

    Article • January 2006, Springer Science + Business Media

    Dr Stephen M Hewitt

  253. Evaluation of Two Phosphorylation Sites Improves the Prognostic Significance of Akt Activation in Non-Small-Cell Lung Cancer Tumors

    Article • Journal of Clinical Oncology, December 2005, American Society of Clinical Oncology (ASCO)

    Dr Stephen M Hewitt

  254. Tissues from population-based cancer registries: a novel approach to increasing research potential

    Article • Human Pathology, July 2005, Elsevier

    Dr Stephen M Hewitt

  255. Tissue microarrays: bridging the gap between research and the clinic

    Article • Expert Review of Proteomics, June 2005, Taylor & Francis

    Dr Stephen M Hewitt

  256. Infrared spectroscopic imaging for histopathologic recognition

    Article • Nature Biotechnology, March 2005, Nature

    Dr Stephen M Hewitt

  257. Schedule-dependent Inhibition of Hypoxia-inducible Factor-1  Protein Accumulation, Angiogenesis, and Tumor Growth by Topotecan in U251-HRE Glioblastoma Xenografts

    Article • Cancer Research, October 2004, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt

  258. A Recurrent Chromosome Breakpoint in Breast Cancer at the NRG1/Neuregulin 1/Heregulin Gene

    Article • Cancer Research, October 2004, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt

  259. Evaluation of Biologic End Points and Pharmacokinetics in Patients With Metastatic Breast Cancer After Treatment With Erlotinib, an Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor

    Article • Journal of Clinical Oncology, August 2004, American Society of Clinical Oncology (ASCO)

    Dr Stephen M Hewitt

  260. High Throughput Fourier Transform Infrared Spectroscopic Imaging for Histopathology

    Article • Microscopy and Microanalysis, August 2004, Cambridge University Press

    Dr Stephen M Hewitt

  261. Modulation of Tumor-host Interactions, Angiogenesis, and Tumor Growth by Tissue Inhibitor of Metalloproteinase 2 via a Novel Mechanism

    Article • Cancer Research, July 2004, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt

  262. Discovery of Protein Biomarkers for Renal Diseases

    Article • Journal of the American Society of Nephrology, July 2004, American Society of Nephrology

    Dr Stephen M Hewitt

  263. Chromatin Remodeling Factors and BRM/BRG1 Expression as Prognostic Indicators in Non-Small Cell Lung Cancer

    Article • Clinical Cancer Research, July 2004, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt

  264. Sil overexpression in lung cancer characterizes tumors with increased mitotic activity

    Article • Oncogene, April 2004, Springer Science + Business Media

    Dr Stephen M Hewitt

  265. Randomized, Double-Blind, Placebo-Controlled Phase IIB Trial of the Cyclooxygenase Inhibitor Ketorolac as an Oral Rinse in Oropharyngeal Leukoplakia

    Article • Clinical Cancer Research, March 2004, American Association for Cancer Research (AACR)

    Dr Stephen M Hewitt

  266. The membrane-cytoskeleton linker ezrin is necessary for osteosarcoma metastasis

    Article • Nature Reports Stem Cells, January 2004, Nature

    Dr Stephen M Hewitt

  267. Peak stimulated insulin secretion is associated with specific changes in gene expression profiles in sporadic insulinomas

    Article • Surgery, December 2003, Elsevier

    Dr Stephen M Hewitt

  268. Ethyl pyruvate decreases sepsis-induced acute renal failure and multiple organ damage in aged mice

    Article • Kidney International, November 2003, Elsevier

    Dr Stephen M Hewitt

  269. Comparative Evaluation of Super High-Resolution CT Scan and Virtual Bronchoscopy for the Detection of Tracheobronchial Malignancies*

    Article • CHEST Journal, November 2003, Elsevier

    Dr Stephen M Hewitt

  270. Renal Tumors in the Birt-Hogg-Dubé Syndrome

    Article • The American Journal of Surgical Pathology, December 2002, Wolters Kluwer Health

    Dr Stephen M Hewitt

  271. Post-analysis follow-up and validation of microarray experiments

    Article • Nature Genetics, December 2002, Nature

    Dr Stephen M Hewitt

  272. Frozen protein arrays: A new method for arraying and detecting recombinant and native tissue proteins

    Article • PROTEOMICS, November 2002, Wiley

    Dr Stephen M Hewitt

  273. Microarray Gene Expression Analysis of Murine Tumor Heterogeneity Defined by Dynamic Contrast-Enhanced MRI

    Article • Molecular Imaging, July 2002, SAGE Publications

    Dr Stephen M Hewitt

  274. Erratum

    Article • Cancer, May 2002, Wiley

    Dr Stephen M Hewitt

  275. Retroviral gene transfer of interferon-inducible protein 10 inhibits growth of human melanoma xenografts

    Article • International Journal of Cancer, March 2002, Wiley

    Dr Stephen M Hewitt

  276. Specimen Morcellation after Laparoscopic Radical Nephrectomy: Confirmation of Histologic Diagnosis Using Needle Biopsy

    Article • Journal of Endourology, March 2002, Mary Ann Liebert Inc

    Dr Stephen M Hewitt

  277. Differential expression of the mismatch repair genehMSH2 in malignant prostate tissue is associated with cancer recurrence

    Article • Cancer, January 2002, Wiley

    Dr Stephen M Hewitt

  278. Interleukin-10 inhibits ischemic and cisplatin-induced acute renal injury

    Article • Kidney International, December 2001, Elsevier

    Dr Stephen M Hewitt

  279. Intramedullary Spinal Cord Metastasis from Renal Cell Carcinoma

    Article • Clinical Nuclear Medicine, October 2001, Wolters Kluwer Health

    Dr Stephen M Hewitt

  280. Birt-Hogg-Dubé Syndrome, a Genodermatosis Associated with Spontaneous Pneumothorax and Kidney Neoplasia, Maps to Chromosome 17p11.2

    Article • The American Journal of Human Genetics, October 2001, Elsevier

    Dr Stephen M Hewitt

  281. INTRAOPERATIVE ULTRASOUND DURING RENAL PARENCHYMAL SPARING SURGERY FOR HEREDITARY RENAL CANCERS:: A 10-YEAR EXPERIENCE

    Article • The Journal of Urology, February 2001, Elsevier

    Dr Stephen M Hewitt

  282. Molecular cytogenetic characterization of early and late renal cell carcinomas in Von Hippel-Lindau disease

    Article • Genes Chromosomes and Cancer, January 2001, Wiley

    Dr Stephen M Hewitt

  283. Endothelial Monocyte Activating Polypeptide II Induces Endothelial Cell Apoptosis and May Inhibit Tumor Angiogenesis

    Article • Microvascular Research, July 2000, Elsevier

    Dr Stephen M Hewitt

  284. The Angiogenesis Inhibitor, Endostatin, Does Not Affect Murine Cutaneous Wound Healing

    Article • Journal of Surgical Research, June 2000, Elsevier

    Dr Stephen M Hewitt

  285. Utilization of microdissection and the polymerase chain reaction for the diagnosis of adrenal cortical carcinoma in fine-needle aspiration cytology

    Article • Cancer, August 1999, Wiley

    Dr Stephen M Hewitt

  286. Differential Function of Wilms Tumor Gene WT1 Splice Isoforms in Transcriptional Regulation

    Article • Journal of Biological Chemistry, April 1996, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Stephen M Hewitt

  287. Transcriptional Silencer of the Wilms' Tumor Gene WT1 Contains an Alu Repeat

    Article • Journal of Biological Chemistry, July 1995, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Stephen M Hewitt

  288. Design, Construction, and Use of Tissue Microarrays

    Article • Springer Science + Business Media

    Dr Stephen M Hewitt