All Stories

  1. A method for achieving complete microbial genomes and improving bins from metagenomics data
  2. Genomewide and Enzymatic Analysis Reveals Efficient D-Galacturonic Acid Metabolism in the Basidiomycete Yeast Rhodosporidium toruloides
  3. Genome-wide and enzymatic analysis reveals efficient D-galacturonic acid metabolism in the basidiomycete yeast Rhodosporidium toruloides
  4. Multiplexed CRISPR-Cas9 based genome editing of Rhodosporidium toruloides
  5. Curated BLAST for Genomes
  6. Dual-barcoded shotgun expression library sequencing for high-throughput characterization of functional traits in bacteria
  7. Genetic dissection of interspecific differences in yeast thermotolerance
  8. Evaluation of 244,000 synthetic sequences reveals design principles to optimize translation in Escherichia coli
  9. Dub-seq: dual-barcoded shotgun expression library sequencing for high-throughput characterization of functional traits
  10. KBase: The United States Department of Energy Systems Biology Knowledgebase
  11. Massive Factorial Design Untangles Coding Sequences Determinants Of Translation Efficacy
  12. Massive Phenotypic Measurements Reveal Complex Physiological Consequences Of Differential Translation Efficacies
  13. Environmental Selection, Dispersal, and Organism Interactions Shape Community Assembly in High-Throughput Enrichment Culturing
  14. Programming mRNA decay to modulate synthetic circuit resource allocation
  15. The DOE Systems Biology Knowledgebase (KBase)
  16. Programming mRNA decay to modulate synthetic circuit resource allocation
  17. QTL-guided metabolic engineering of a complex trait
  18. A Comparison of the Costs and Benefits of Bacterial Gene Expression
  19. Metabolic engineering of the oleaginous yeast Rhodosporidium toruloides IFO0880 for lipid overproduction during high-density fermentation
  20. Deep Annotation of Protein Function across Diverse Bacteria from Mutant Phenotypes
  21. Novel Metal Cation Resistance Systems from Mutant Fitness Analysis of Denitrifying Pseudomonas stutzeri
  22. Exometabolomics Assisted Design and Validation of Synthetic Obligate Mutualism
  23. Rapid and Efficient One-Step Metabolic Pathway Integration in E. coli
  24. Rapid and efficient galactose fermentation by engineered Saccharomyces cerevisiae
  25. A Theoretical Lower Bound for Selection on the Expression Levels of Proteins
  26. Measurement and modeling of intrinsic transcription terminators
  27. Transcriptional bursting explains the noise-versus-mean relationship in mRNA and protein levels
  28. Gene Amplification on Demand Accelerates Cellobiose Utilization in Engineered Saccharomyces cerevisiae
  29. Lateral Gene Transfer in a Heavy Metal-Contaminated-Groundwater Microbial Community
  30. A Comparison of the Costs and Benefits of Bacterial Gene Expression
  31. Weakly Deleterious Mutations and Low Rates of Recombination Limit the Impact of Natural Selection on Bacterial Genomes
  32. Grand challenges in space synthetic biology
  33. Genome-Wide Tuning of Protein Expression Levels to Rapidly Engineer Microbial Traits
  34. EngineeringRhodosporidium toruloidesfor increased lipid production
  35. Complete Genome Sequences of Four Escherichia coli ST95 Isolates from Bloodstream Infections
  36. A Slow-Release Substrate Stimulates Groundwater Microbial Communities for Long-Term in Situ Cr(VI) Reduction
  37. Comparative metagenomics reveals impact of contaminants on groundwater microbiomes
  38. The essential gene set of a photosynthetic organism
  39. Determining Roles of Accessory Genes in Denitrification by Mutant Fitness Analyses
  40. Complete Genome Sequence of Pelosinus fermentans JBW45, a Member of a Remarkably Competitive Group of Negativicutes in the Firmicutes ...
  41. A Method to Constrain Genome-Scale Models with 13C Labeling Data
  42. Molybdenum Availability Is Key to Nitrate Removal in Contaminated Groundwater Environments
  43. Complete Genome Sequence of Cupriavidus basilensis 4G11, Isolated from the Oak Ridge Field Research Center Site
  44. Novel Mechanism for Scavenging of Hypochlorite Involving a Periplasmic Methionine-Rich Peptide and Methionine Sulfoxide Reductase
  45. Rapid Quantification of Mutant Fitness in Diverse Bacteria by Sequencing Randomly Bar-Coded Transposons
  46. Natural Bacterial Communities Serve as Quantitative Geochemical Biosensors
  47. Dynamic Succession of Groundwater Functional Microbial Communities in Response to Emulsified Vegetable Oil Amendment during SustainedIn SituU(VI) Reduction
  48. Rapid selective sweep of pre-existing polymorphisms and slow fixation of new mutations in experimental evolution of Desulfovibrio vulgaris
  49. Monofluorophosphate Is a Selective Inhibitor of Respiratory Sulfate-Reducing Microorganisms
  50. Independence of Nitrate and Nitrite Inhibition of Desulfovibrio vulgaris Hildenborough and Use of Nitrite as a Substrate for Growth
  51. Pattern formation with a compartmental lateral inhibition system
  52. Mechanisms of direct inhibition of the respiratory sulfate-reduction pathway by (per)chlorate and nitrate
  53. Towards synthetic biological approaches to resource utilization on space missions
  54. The genetic basis of energy conservation in the sulfate-reducing bacterium Desulfovibrio alaskensis G20
  55. Rex (Encoded by DVU_0916) in Desulfovibrio vulgaris Hildenborough Is a Repressor of Sulfate Adenylyl Transferase and Is Regulated by NADH
  56. Characterization of Wastewater Treatment Plant Microbial Communities and the Effects of Carbon Sources on Diversity in Laboratory Models
  57. Selection of chromosomal DNA libraries using a multiplex CRISPR system
  58. Towards an Informative Mutant Phenotype for Every Bacterial Gene
  59. Conservation of Transcription Start Sites within Genes across a Bacterial Genus
  60. Interactive XCMS Online: Simplifying Advanced Metabolomic Data Processing and Subsequent Statistical Analyses
  61. Metabolomic data streaming for biology-dependent data acquisition
  62. Functional Genomics with a Comprehensive Library of Transposon Mutants for the Sulfate-Reducing Bacterium Desulfovibrio alaskensis G20
  63. Avoidance of Truncated Proteins from Unintended Ribosome Binding Sites within Heterologous Protein Coding Sequences
  64. Indirect and suboptimal control of gene expression is widespread in bacteria
  65. Dissecting a complex chemical stress: chemogenomic profiling of plant hydrolysates
  66. Genetic basis for nitrate resistance in Desulfovibrio strains
  67. A versatile framework for microbial engineering using synthetic non-coding RNAs
  68. The energy‐conserving electron transfer system used by Desulfovibrio alaskensis strain G20 during pyruvate fermentation involves reduction of endogenously formed fumarate and cytoplasmic and membrane‐bound complexes,...
  69. Stochasticity, succession, and environmental perturbations in a fluidic ecosystem
  70. Transcript level and sequence determinants of protein abundance and noise in Escherichia coli
  71. D-Tailor: automated analysis and design of DNA sequences
  72. Fermentation of hydrolysate detoxified by pervaporation through block copolymer membranes
  73. Hexavalent Chromium Reduction under Fermentative Conditions with Lactate Stimulated Native Microbial Communities
  74. Synthetic biology
  75. A wise consistency: engineering biology for conformity, reliability, predictability
  76. Changes in microbial dynamics during long-term decomposition in tropical forests
  77. “Replica-Extraction-Transfer” Nanostructure-Initiator Mass Spectrometry Imaging of Acoustically Printed Bacteria
  78. Control of methionine metabolism by the SahR transcriptional regulator in Proteobacteria
  79. Flexibility of Syntrophic Enzyme Systems in Desulfovibrio Species Ensures Their Adaptation Capability to Environmental Changes
  80. StressChip as a High-Throughput Tool for Assessing Microbial Community Responses to Environmental Stresses
  81. Composability of regulatory sequences controlling transcription and translation in Escherichia coli
  82. New Family of Tungstate-Responsive Transcriptional Regulators in Sulfate-Reducing Bacteria
  83. Genetic Selection for Context-Dependent Stochastic Phenotypes: Sp1 and TATA Mutations Increase Phenotypic Noise in HIV-1 Gene Expression
  84. Effects of Genetic Variation on the E. coli Host-Circuit Interface
  85. Characterization of NaCl tolerance in Desulfovibrio vulgaris Hildenborough through experimental evolution
  86. RegTransBase – a database of regulatory sequences and interactions based on literature: a resource for investigating transcriptional regulation in prokaryotes
  87. Measurement and modeling of intrinsic transcription terminators
  88. Precise and reliable gene expression via standard transcription and translation initiation elements
  89. Quantitative estimation of activity and quality for collections of functional genetic elements
  90. Modular Design of a Synthetic Payload Delivery Device
  91. Rational and Evolutionary Engineering Approaches Uncover a Small Set of Genetic Changes Efficient for Rapid Xylose Fermentation in Saccharomyces cerevisiae
  92. Modeling coagulation activation in trauma patients
  93. Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression
  94. Metallochaperones Regulate Intracellular Copper Levels
  95. From Biological Parts to Circuit Design
  96. Correction: Global analysis of host response to induction of a latent bacteriophage
  97. RegPrecise 3.0 – A resource for genome-scale exploration of transcriptional regulation in bacteria
  98. Inference of gene regulatory networks from genome-wide knockout fitness data
  99. Variation among Desulfovibrio Species in Electron Transfer Systems Used for Syntrophic Growth
  100. metaMicrobesOnline: phylogenomic analysis of microbial communities
  101. Metabolic Footprinting of Mutant Libraries to Map Metabolite Utilization to Genotype
  102. Sequestration-based bistability enables tuning of the switching boundaries and design of a latch
  103. Transcription Factor Family-Based Reconstruction of Singleton Regulons and Study of the Crp/Fnr, ArsR, and GntR Families in Desulfovibrionales Genomes
  104. Engineering robust control of two-component system phosphotransfer using modular scaffolds
  105. An adaptor from translational to transcriptional control enables predictable assembly of complex regulation
  106. RNA processing enables predictable programming of gene expression
  107. Draft Genome Sequence of Pelosinus fermentans JBW45, Isolated during In Situ Stimulation for Cr(VI) Reduction
  108. Draft Genome Sequences for Two Metal-Reducing Pelosinus fermentans Strains Isolated from a Cr(VI)-Contaminated Site and for Type Strain R7
  109. Deletion of the Desulfovibrio vulgaris Carbon Monoxide Sensor Invokes Global Changes in Transcription
  110. Functional responses of methanogenic archaea to syntrophic growth
  111. Manipulation of the carbon storage regulator system for metabolite remodeling and biofuel production in Escherichia coli
  112. Contextualizing context for synthetic biology – identifying causes of failure of synthetic biological systems
  113. Transcriptomic and proteomic analyses of Desulfovibrio vulgaris biofilms: Carbon and energy flow contribute to the distinct biofilm growth state
  114. Rationally designed families of orthogonal RNA regulators of translation
  115. Engineering naturally occurring trans-acting non-coding RNAs to sense molecular signals
  116. Preface
  117. Chromatin accessibility at the HIV LTR promoter sets a threshold for NF-κB mediated viral gene expression
  118. Functional Characterization of Crp/Fnr-Type Global Transcriptional Regulators in Desulfovibrio vulgaris Hildenborough
  119. Evidence-Based Annotation of Gene Function in Shewanella oneidensis MR-1 Using Genome-Wide Fitness Profiling across 121 Conditions
  120. Systematic mapping of two component response regulators to gene targets in a model sulfate reducing bacterium
  121. Toward rational design of bacterial genomes
  122. Varying virulence: epigenetic control of expression noise and disease processes
  123. Complete genome sequence of “Enterobacter lignolyticus” SCF1
  124. Towards a Rigorous Network of Protein-Protein Interactions of the Model Sulfate Reducer Desulfovibrio vulgaris Hildenborough
  125. Joint DAC/IWBDA special session design and synthesis of biological circuits
  126. Modeling sporulation decisions in Bacillus subtilis as optimal evolutionary decision-making
  127. How sulphate-reducing microorganisms cope with stress: lessons from systems biology
  128. Design and Construction of a Double Inversion Recombination Switch for Heritable Sequential Genetic Memory
  129. The hunt for the biological transistor
  130. Network News: Innovations in 21st Century Systems Biology
  131. Regulation of transcription by unnatural amino acids
  132. Microfluidic fluorescence in situ hybridization and flow cytometry (μFlowFISH)
  133. Simulated niche partitioning by bacteria
  134. Meta-analysis of global metabolomics and proteomics data to link alterations with phenotype
  135. Comparative genomic reconstruction of transcriptional networks controlling central metabolism in the Shewanella genus
  136. Development of a Low Bias Method for Characterizing Viral Populations Using Next Generation Sequencing Technology
  137. HIV Promoter Integration Site Primarily Modulates Transcriptional Burst Size Rather Than Frequency
  138. Inference of binding sites with a Bayesian multiple-instance motif discovery method
  139. Computational Models of HIV-1 Resistance to Gene Therapy Elucidate Therapy Design Principles
  140. Conservation of Modules but not Phenotype in Bacterial Response to Environmental Stress
  141. Revisiting Modes of energy generation in sulfate reducing bacteria
  142. Development of a Model, Metal-reducing Microbial Community for a System Biology Level Assessment of Desulfovibrio vulgaris as part of a Community
  143. Genetic Adaptation to Salt Stress in Experimental Evolution of Desulfovibrio vulgaris Hildenborough
  144. Identification of Small RNAs in Desulfovibrio vulgaris Hildenborough
  145. Hydrogen peroxide‐induced oxidative stress responses in Desulfovibrio vulgaris Hildenborough
  146. Impact of elevated nitrate on sulfate-reducing bacteria: a comparative Study of Desulfovibrio vulgaris
  147. Microbial Community Dynamics of Lactate Enriched Hanford Groundwaters
  148. Detailed Simulations of Cell Biology with Smoldyn 2.1
  149. FastTree 2 – Approximately Maximum-Likelihood Trees for Large Alignments
  150. BglBricks: A flexible standard for biological part assembly
  151. Contribution of mobile genetic elements to Desulfovibrio vulgaris genome plasticity
  152. Invariability of central metabolic flux distribution in Shewanella oneidensis MR‐1 under environmental or genetic perturbations
  153. Novel insights into iron metabolism by integrating deletome and transcriptome analysis in an iron deficiency model of the yeast Saccharomyces cerevisiae
  154. Control of Stochastic Gene Expression by Host Factors at the HIV Promoter
  155. Shape, Size, and Robustness: Feasible Regions in the Parameter Space of Biochemical Networks
  156. Stochastic Models of Biological Processes
  157. Evolution, ecology and the engineered organism: lessons for synthetic biology
  158. Snapshot of iron response in Shewanella oneidensis by gene network reconstruction
  159. Toward scalable parts families for predictable design of biological circuits
  160. Metabolic flux analysis of Shewanella spp. reveals evolutionary robustness in central carbon metabolism
  161. FastBLAST: Homology Relationships for Millions of Proteins
  162. A Dual Receptor Crosstalk Model of G-Protein-Coupled Signal Transduction
  163. Design and Construction of a Double Inversion Recombination Switch for Heritable Sequential Genetic Memory
  164. Setting the standard in synthetic biology
  165. Memory in Microbes: Quantifying History-Dependent Behavior in a Bacterium
  166. Horizontal gene transfer and the evolution of transcriptional regulation in Escherichia coli
  167. Appreciation of the Machinations of the Blind Watchmaker
  168. Genetics and Genomics of Sulfate Respiration in Desulfovibrio
  169. Processing Single-Cell Single-Molecule Genomic Information: New Methods for New Data
  170. Identification of Genes Involved in the Toxic Response of Saccharomyces cerevisiae against Iron and Copper Overload by Parallel Analysis of Deletion Mutants
  171. Response of Desulfovibrio vulgaris to Alkaline Stress
  172. Orthologous Transcription Factors in Bacteria Have Different Functions and Regulate Different Genes
  173. A Mechanical Explanation for Cytoskeletal Rings and Helices in Bacteria
  174. Global analysis of host response to induction of a latent bacteriophage
  175. Environmental signal integration by a modular AND gate
  176. Identification of Genes Involved in the Toxic Response of Saccharomyces cerevisiae against Iron and Copper Overload by Parallel Analysis of Deletion Mutants
  177. Analysis of a Ferric Uptake Regulator (Fur) Mutant of Desulfovibrio vulgaris Hildenborough
  178. Systems Biology: A Switch for Sex
  179. Cell-Wide Responses to Low-Oxygen Exposure in Desulfovibrio vulgaris Hildenborough
  180. Efficient stochastic sensitivity analysis of discrete event systems
  181. RegTransBase--a database of regulatory sequences and interactions in a wide range of prokaryotic genomes
  182. Systems Biology
  183. From Fluctuations to Phenotypes: The Physiology of Noise
  184. Deviant effects in molecular reaction pathways
  185. Morphology matters in immune cell chemotaxis: membrane asymmetry affects amplification
  186. Simulating cell biology
  187. The Life-Cycle of Operons
  188. Genomics for environmental microbiology
  189. Salt Stress in Desulfovibrio vulgaris Hildenborough: an Integrated Genomics Approach
  190. Energetic Consequences of Nitrite Stress in Desulfovibrio vulgaris Hildenborough, Inferred from Global Transcriptional Analysis
  191. The Histidine Operon Is Ancient
  192. A tightly regulated inducible expression system utilizing the fim inversion recombination switch
  193. Model Discrimination Using Data Collaboration
  194. Global Analysis of Heat Shock Response in Desulfovibrio vulgaris Hildenborough
  195. Transcriptome Profiling of Shewanella oneidensis Gene Expression following Exposure to Acidic and Alkaline pH
  196. Correction: The Life-Cycle of Operons
  197. Automated Abstraction Methodology for Genetic Regulatory Networks
  198. Environmentally Controlled Invasion of Cancer Cells by Engineered Bacteria
  199. Averaging Methods for Stochastic Dynamics of Complex Reaction Networks: Description of Multiscale Couplings
  200. The Evolution of Two-Component Systems in Bacteria Reveals Different Strategies for Niche Adaptation
  201. Cellular Response of Shewanella oneidensis to Strontium Stress
  202. Dissimilatory Metabolism of Nitrogen Oxides in Bacteria: Comparative Reconstruction of Transcriptional Networks
  203. Genome-Wide Requirements for Resistance to Functionally Distinct DNA-Damaging Agents
  204. Numerical computation of diffusion on a surface
  205. Phosphatase localization in bacterial chemotaxis: divergent mechanisms, convergent principles
  206. Stochastic Gene Expression in a Lentiviral Positive-Feedback Loop: HIV-1 Tat Fluctuations Drive Phenotypic Diversity
  207. The MicrobesOnline Web site for comparative genomics
  208. Interruptions in gene expression drive highly expressed operons to the leading strand of DNA replication
  209. A latent variable model for chemogenomic profiling
  210. Operon formation is driven by co-regulation and not by horizontal gene transfer
  211. Diversity in times of adversity: probabilistic strategies in microbial survival games
  212. A microbial modified prisoner's dilemma game: how frequency-dependent selection can lead to random phase variation
  213. Transcriptome Analysis of Shewanella oneidensis MR-1 in Response to Elevated Salt Conditions
  214. A novel method for accurate operon predictions in all sequenced prokaryotes
  215. Stochastic amplification and signaling in enzymatic futile cycles through noise-induced bistability with oscillations
  216. Dissimilatory Metabolism of Nitrogen Oxides in Bacteria: Comparative Reconstruction of Transcriptional Networks
  217. Autonomous Mobile Robot Control Based on White Blood Cell Chemotaxis
  218. Global Transcriptome Analysis of the Heat Shock Response of Shewanella oneidensis
  219. An Allosteric Model for Transmembrane Signaling in Bacterial Chemotaxis
  220. The old switcheroo: new tricks revealed in ‘Phage Lambda Revisited’
  221. Response experiments for nonlinear systems with application to reaction kinetics and genetics
  222. The evolution of genetic regulatory systems in bacteria
  223. Design and Diversity in Bacterial Chemotaxis: A Comparative Study in Escherichia coli and Bacillus subtilis
  224. Data Standards for the Genomes to Life Program
  225. Theoretical Design of a Gene Therapy To Prevent AIDS but Not Human Immunodeficiency Virus Type 1 Infection
  226. Motifs, modules and games in bacteria
  227. Biological networks
  228. Stochastic chemical kinetics and the quasi-steady-state assumption: Application to the Gillespie algorithm
  229. The systems biology markup language (SBML): a medium for representation and exchange of biochemical network models
  230. Erratum: Control, exploitation and tolerance of intracellular noise
  231. Overview of the Alliance for Cellular Signaling
  232. Control, exploitation and tolerance of intracellular noise
  233. Signal Processing by Simple Chemical Systems
  234. GENETIC“CODE”: Representations and Dynamical Models of Genetic Components and Networks
  235. Functional profiling of the Saccharomyces cerevisiae genome
  236. Motifs and modules in cellular signal processing
  237. Fifteen Minutes of fim : Control of Type 1 Pili Expression in E. coli
  238. Motifs and modules in cellular signal processing
  239. Synthetic cell biology
  240. Control Motifs for Intracellular Regulatory Networks*
  241. On the deduction of chemical reaction pathways from measurements of time series of concentrations
  242. Signal processing by biochemical reaction networks
  243. Gene regulation: Towards a circuit engineering discipline
  244. It’s a noisy business! Genetic regulation at the nanomolar scale
  245. SIMULATION OF PROKARYOTIC GENETIC CIRCUITS
  246. Steady-State Measurements on the Fructose 6-Phosphate/Fructose 1,6-Bisphosphate Interconversion Cycle
  247. Experimental Evidence for Turing Structures
  248. Statistical Construction of Chemical Reaction Mechanisms from Measured Time-Series
  249. Digital Imaging Spectroscopy
  250. Optimizing Nucleotide Mixtures to Encode Specific Subsets of Amino Acids for Semi-Random Mutagenesis
  251. Applications of Imaging Spectroscopy in Molecular Biology II. Colony Screening Based on Absorption Spectra
  252. Modeling and Network Organization
  253. Data and Databases
  254. Adam Arkin at the 2012 DOE JGI Genomics of Energy & Environment Meeting
  255. Motifs and modules in cellular signal processing: applications to microbial stress response pathways
  256. Playing practical games with bacteria and viruses: exploring the molecular mechanisms behind clever cellular stratagems