All Stories

  1. Evolution of a restriction factor by domestication of a yeast retrotransposon

    Article • Molecular Biology and Evolution, March 2024, Oxford University Press (OUP)

    Professor David J. Garfinkel

  2. Horizontal transfer and recombination fuel Ty4 retrotransposon evolution in Saccharomyces.

    Article • December 2023, Cold Spring Harbor Laboratory Press

    Professor David J. Garfinkel

  3. A prion domain is required for assembly of a functional retrotransposon virus particle.

    Article • Proceedings of the National Academy of Sciences, July 2023, Proceedings of the National Academy of Sciences

    David J. Garfinkel, Professor David J. Garfinkel

  4. Reproducible evaluation of transposable element detectors with McClintock 2 guides accurate inference of Ty insertion patterns in yeast

    Article • Mobile DNA, July 2023, Springer Science + Business Media

    Professor David J. Garfinkel

  5. An interchangeable prion-like domain is required for Ty1 retrotransposition

    Article • February 2023, Cold Spring Harbor Laboratory Press

    Professor David J. Garfinkel

  6. Reproducible evaluation of short-read transposable element detectors and species-wide data mining of insertion patterns in yeast.

    Article • February 2023, Cold Spring Harbor Laboratory Press

    Professor David J. Garfinkel

  7. Cell Compartment-Specific Folding of Ty1 Long Terminal Repeat Retrotransposon RNA Genome

    Article • Viruses, September 2022, MDPI AG

    Professor David J. Garfinkel

  8. Cell Compartment-specific Folding of Ty1 Long Terminal Repeat Retrotransposon RNA Genome

    Article • July 2022, MDPI AG

    Professor David J. Garfinkel

  9. Genome Assembly of the Ty1-Less Saccharomyces paradoxus Strain DG1768

    Article • Microbiology Resource Announcements, January 2022, ASM Journals

    Professor David J. Garfinkel

  10. Long-Read Genome Assembly of Saccharomyces uvarum Strain CBS 7001

    Article • Microbiology Resource Announcements, January 2022, ASM Journals

    Professor David J. Garfinkel

  11. Structure of a Ty1 restriction factor reveals the molecular basis of transposition copy number control

    Article • Nature Communications, September 2021, Springer Science + Business Media

    Professor David J. Garfinkel

  12. RNA Binding Properties of the Ty1 LTR-Retrotransposon Gag Protein

    Article • International Journal of Molecular Sciences, August 2021, MDPI AG

    Professor David J. Garfinkel

  13. In vivo structure of the Ty1 retrotransposon RNA genome

    Article • Nucleic Acids Research, February 2021, Oxford University Press (OUP)

    Professor David J. Garfinkel

  14. Evolution of Ty1 copy number control in yeast by horizontal transfer and recombination

    Article • PLoS Genetics, February 2020, PLOS

    Professor David J. Garfinkel, David J. Garfinkel

  15. Retroviral-like determinants and functions required for dimerization of Ty1 retrotransposon RNA

    Article • RNA Biology, August 2019, Taylor & Francis

    Professor David J. Garfinkel, David J. Garfinkel

  16. Evolution of Ty1 copy number control in yeast by horizontal transfer of a gag gene

    Article • August 2019, Cold Spring Harbor Laboratory Press

    Professor David J. Garfinkel

  17. Ribosome Biogenesis Modulates Ty1 Copy Number Control in Saccharomyces cerevisiae

    Article • Genetics, October 2017, Oxford University Press (OUP)

    Professor David J. Garfinkel

  18. Structure of Ty1 Internally Initiated RNA Influences Restriction Factor Expression

    Article • Viruses, April 2017, MDPI AG

    Professor David J. Garfinkel

  19. Erratum for Saha et al., A trans -Dominant Form of Gag Restricts Ty1 Retrotransposition and Mediates Copy Number Control

    Article • Journal of Virology, May 2016, ASM Journals

    Professor David J. Garfinkel

  20. Erratum to: ribosomal protein and biogenesis factors affect multiple steps during movement of the Saccharomyces cerevisiae Ty1 retrotransposon

    Article • Mobile DNA, February 2016, Springer Science + Business Media

    Professor David J. Garfinkel

  21. A self-encoded capsid derivative restricts Ty1 retrotransposition in Saccharomyces

    Article • Current Genetics, December 2015, Springer Science + Business Media

    Professor David J. Garfinkel

  22. Ribosomal protein and biogenesis factors affect multiple steps during movement of the Saccharomyces cerevisiae Ty1 retrotransposon

    Article • Mobile DNA, December 2015, Springer Science + Business Media

    Professor David J. Garfinkel

  23. The Ty1 Retrotransposon Restriction Factor p22 Targets Gag

    Article • PLoS Genetics, October 2015, PLOS

    Professor David J. Garfinkel

  24. Ty1 retrovirus-like element Gag contains overlapping restriction factor and nucleic acid chaperone functions

    Article • Nucleic Acids Research, July 2015, Oxford University Press (OUP)

    Professor David J. Garfinkel

  25. Atrans-Dominant Form of Gag Restricts Ty1 Retrotransposition and Mediates Copy Number Control

    Article • Journal of Virology, January 2015, ASM Journals

    Professor David J. Garfinkel

  26. Influence of RNA structural elements on Ty1 retrotransposition

    Article • Mobile Genetic Elements, March 2013, Taylor & Francis

    Professor David J. Garfinkel

  27. Exploring Ty1 retrotransposon RNA structure within virus-like particles

    Article • Nucleic Acids Research, October 2012, Oxford University Press (OUP)

    Professor David J. Garfinkel

  28. Ty1 Gag Enhances the Stability and Nuclear Export of Ty1 mRNA

    Article • Traffic, October 2012, Wiley

    Professor David J. Garfinkel

  29. BUD22 Affects Ty1 Retrotransposition and Ribosome Biogenesis in Saccharomyces cerevisiae

    Article • Genetics, August 2010, Oxford University Press (OUP)

    Professor David J. Garfinkel

  30. P-Body Components Are Required for Ty1 Retrotransposition during Assembly of Retrotransposition-Competent Virus-Like Particles

    Article • Molecular and Cellular Biology, November 2009, ASM Journals

    Professor David J. Garfinkel

  31. Posttranslational interference of Ty1 retrotransposition by antisense RNAs

    Article • Proceedings of the National Academy of Sciences, September 2009, Proceedings of the National Academy of Sciences

    Professor David J. Garfinkel

  32. Functional Analysis of N-Terminal Residues of Ty1 Integrase

    Article • Journal of Virology, July 2009, ASM Journals

    Professor David J. Garfinkel

  33. Chromatin-Associated Genes Protect the Yeast Genome From Ty1 Insertional Mutagenesis

    Article • Genetics, January 2008, Genetics Society of America

    Professor David J. Garfinkel

  34. S-Phase Checkpoint Pathways Stimulate the Mobility of the Retrovirus-Like Transposon Ty1

    Article • Molecular and Cellular Biology, October 2007, ASM Journals

    Professor David J. Garfinkel

  35. Retrotransposon Suicide: Formation of Ty1 Circles and Autointegration via a Central DNA Flap

    Article • Journal of Virology, September 2006, ASM Journals

    Professor David J. Garfinkel

  36. p205, A potential tumor suppressor, inhibits cell proliferation via multiple pathways of cell cycle regulation

    Article • FEBS Letters, January 2006, Wiley

    Professor David J. Garfinkel, Dr Philipp Kaldis

  37. Sensitive Phenotypic Detection of Minor Drug-Resistant Human Immunodeficiency Virus Type 1 Reverse Transcriptase Variants

    Article • Journal of Clinical Microbiology, November 2005, ASM Journals

    Professor David J. Garfinkel

  38. Ty1 Copy Number Dynamics in Saccharomyces

    Article • Genetics, January 2005, Genetics Society of America

    Professor David J. Garfinkel

  39. Genome evolution mediated by Ty elements in <i>Saccharomyces</i>

    Article • Cytogenetic and Genome Research, January 2005, Karger Publishers

    Professor David J. Garfinkel

  40. Analysis of a Ty1-less variant ofSaccharomyces paradoxus: the gain and loss of Ty1 elements

    Article • Yeast, June 2004, Wiley

    Professor David J. Garfinkel

  41. Functional profiling of the Saccharomyces cerevisiae genome

    Article • Nature, July 2002, Nature

    Professor Adam P Arkin, Professor David J. Garfinkel

  42. Nucleotide Excision Repair, Genome Stability, and Human Disease: New Insight from Model Systems

    Article • Journal of Biomedicine and Biotechnology, January 2002, Hindawi Publishing Corporation

    Professor David J. Garfinkel

  43. Chemical Cleavage at Aspartyl Residues for Protein Identification

    Article • Analytical Chemistry, November 2001, American Chemical Society (ACS)

    Professor David J. Garfinkel

  44. Correct Integration of Model Substrates by Ty1 Integrase

    Article • Journal of Virology, December 2000, ASM Journals

    Professor David J. Garfinkel

  45. The Genomic RNA in Ty1 Virus-Like Particles Is Dimeric

    Article • Journal of Virology, November 2000, ASM Journals

    Professor David J. Garfinkel

  46. Nucleotide Excision Repair/TFIIH Helicases Rad3 and Ssl2 Inhibit Short-Sequence Recombination and Ty1 Retrotransposition by Similar Mechanisms

    Article • Molecular and Cellular Biology, April 2000, ASM Journals

    Professor David J. Garfinkel

  47. New lines of host defense: inhibition of Ty1 retrotransposition by Fus3p and NER/TFIIH

    Article • Trends in Genetics, February 1999, Elsevier

    Professor David J. Garfinkel

  48. Hybrid Ty1/HIV-1 elements used to detect inhibitors and monitor the activity of HIV-1 reverse transcriptase

    Article • Proceedings of the National Academy of Sciences, November 1998, Proceedings of the National Academy of Sciences

    Professor David J. Garfinkel

  49. Utilization of microhomologous recombination in yeast to generate targeting constructs for mammalian genes

    Article • Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, June 1998, Elsevier

    Professor David J. Garfinkel

  50. Posttranslational Regulation of Ty1 Retrotransposition by Mitogen-Activated Protein Kinase Fus3

    Article • Molecular and Cellular Biology, May 1998, ASM Journals

    Professor David J. Garfinkel

  51. A Ty1 Integrase Nuclear Localization Signal Required for Retrotransposition

    Article • Molecular and Cellular Biology, February 1998, ASM Journals

    Professor David J. Garfinkel

  52. 7 Ty Mutagenesis

    Article • January 1998, Elsevier

    Professor David J. Garfinkel

  53. Genetic redundancy between SPT23 and MGA2: regulators of Ty-induced mutations and Ty1 transcription in Saccharomyces cerevisiae.

    Article • Molecular and Cellular Biology, August 1997, ASM Journals

    Professor David J. Garfinkel

  54. Genetic loose change: How retroelements and reverse transcriptase heal broken chromosomes

    Article • Trends in Microbiology, May 1997, Elsevier

    Professor David J. Garfinkel

  55. Transcriptional silencing of Ty1 elements in the RDN1 locus of yeast.

    Article • Genes & Development, January 1997, Cold Spring Harbor Laboratory Press

    Professor David J. Garfinkel

  56. HIV reverse transcription in yeast

    Article • Nature, March 1996, Springer Science + Business Media

    Professor David J. Garfinkel

  57. Presence ofTy1-CopiaGroup Retrotransposon Sequences in the Potato Late Blight PathogenPhytophthora infestans

    Article • Molecular Plant-Microbe Interactions, January 1996, Scientific Societies

    Professor David J. Garfinkel

  58. Substrate specificity of Ty1 integrase

    Article • Journal of Virology, August 1995, ASM Journals

    Professor David J. Garfinkel

  59. Efficient homologous recombination of Ty1 element cDNA when integration is blocked.

    Article • Molecular and Cellular Biology, October 1994, ASM Journals

    Professor David J. Garfinkel

  60. Expression and partial purification of enzymaticallyactive recombinant Ty1 integrase in Saccharomyces cerevisiae.

    Article • Proceedings of the National Academy of Sciences, March 1994, Proceedings of the National Academy of Sciences

    Professor David J. Garfinkel

  61. Molecular characterization of theSPT23 gene: A dosage-dependent suppressor of ty-induced promoter mutations fromSaccharomyces cerevisiae

    Article • Yeast, January 1994, Wiley

    Professor David J. Garfinkel

  62. Posttranslational control of Ty1 retrotransposition occurs at the level of protein processing.

    Article • Molecular and Cellular Biology, June 1992, ASM Journals

    Professor David J. Garfinkel

  63. Retroelements in Microorganisms

    Article • January 1992, Springer Science + Business Media

    Professor David J. Garfinkel

  64. RNA-mediated recombination in S. cerevisiae

    Article • Cell, October 1991, Elsevier

    Professor David J. Garfinkel

  65. Proteolytic processing of pol-TYB proteins from the yeast retrotransposon Ty1

    Article • Journal of Virology, September 1991, ASM Journals

    Professor David J. Garfinkel

  66. Regulation of retrotransposition in Saccharomyces cerevisiae

    Article • Molecular Microbiology, August 1991, Wiley

    Professor David J. Garfinkel

  67. Single-step selection for Ty1 element retrotransposition.

    Article • Proceedings of the National Academy of Sciences, February 1991, Proceedings of the National Academy of Sciences

    Professor David J. Garfinkel

  68. [23] Ty mutagenesis in Saccharomyces cerevisiae

    Article • January 1991, Elsevier

    Professor David J. Garfinkel

  69. Multimeric arrays of the yeast retrotransposon Ty.

    Article • Molecular and Cellular Biology, June 1990, ASM Journals

    Professor David J. Garfinkel

  70. Ty RNA levels determine the spectrum of retrotransposition events that activate gene expression in Saccharomyces cerevisiae

    Article • January 1990, Springer Science + Business Media

    Professor David J. Garfinkel

  71. The biology and exploitation of the retrotransposon Ty in Saccharomyces cerevisiae

    Article • Genome, January 1989, Canadian Science Publishing

    Professor David J. Garfinkel

  72. Transpositional competence and transcription of endogenous Ty elements in Saccharomyces cerevisiae: implications for regulation of transposition.

    Article • Molecular and Cellular Biology, September 1988, ASM Journals

    Professor David J. Garfinkel

  73. Functional organization of the retrotransposon Ty from Saccharomyces cerevisiae: Ty protease is required for transposition.

    Article • Molecular and Cellular Biology, April 1988, ASM Journals

    Professor David J. Garfinkel

  74. The mechanism and consequences of retrotransposition

    Article • Trends in Genetics, January 1986, Elsevier

    Professor David J. Garfinkel

  75. An Agrobacterium transformation in the evolution of the genus Nicotiana

    Article • Nature, January 1986, Springer Science + Business Media

    Professor David J. Garfinkel

  76. Ty element transposition: Reverse transcriptase and virus-like particles

    Article • Cell, September 1985, Elsevier

    Professor David J. Garfinkel

  77. Ty elements transpose through an RNA intermediate

    Article • Cell, March 1985, Elsevier

    Professor David J. Garfinkel

  78. Nucleotide sequence of the tms genes of the pTiA6NC octopine Ti plasmid: two gene products involved in plant tumorigenesis.

    Article • Proceedings of the National Academy of Sciences, March 1984, Proceedings of the National Academy of Sciences

    Professor David J. Garfinkel

  79. Sequences homologous to Agrobacterium rhizogenes T-DNA in the genomes of uninfected plants

    Article • Nature, January 1983, Springer Science + Business Media

    Professor David J. Garfinkel

  80. CURRENT DEVELOPMENTS IN THE TRANSFORMATION OF PLANTS

    Article • January 1983, Elsevier

    Professor David J. Garfinkel

  81. Cytokinin/auxin balance in crown gall tumors is regulated by specific loci in the T-DNA

    Article • Proceedings of the National Academy of Sciences, January 1983, Proceedings of the National Academy of Sciences

    Professor David J. Garfinkel

  82. CROWN GALL – NATURE'S GENETIC ENGINEER

    Article • January 1982, Elsevier

    Professor David J. Garfinkel

  83. Genetic analysis of crown gall: Fine structure map of the T-DNA by site-directed mutagenesis

    Article • Cell, November 1981, Elsevier

    Professor David J. Garfinkel

  84. A Mutational and Transcriptional Analysis of a Tumor Inducing Plasmid of Agrobacterium tumefaciens

    Article • January 1981, Springer Science + Business Media

    Professor David J. Garfinkel

  85. Agrobacterium tumefaciens mutants affected in crown gall tumorigenesis and octopine catabolism

    Article • Journal of Bacteriology, November 1980, ASM Journals

    Professor David J. Garfinkel

  86. The boundaries and copy numbers of Ti plasmid T-DNA vary in crown gall tumors

    Article • March 1980, Springer Science + Business Media

    Professor David J. Garfinkel

  87. Insertional Mutagenesis by Ty Elements in Saccharomyces cerevisiae

    Article • Springer Science + Business Media

    Professor David J. Garfinkel