What is it about?
The utility and comparison of PLA2R IHC with ELISA and IIF for accurate diagnosis of primary MN
Featured Image
Why is it important?
PLA2R IHC has a higher sensitivity and specificity with cost effectiveness and persistent results than IIF and Western Blot. This serves to provide an accurate and fast diagnosis for primary MN especially in situations where antiPLA2R antibodies in serum are negative.
Perspectives
PLA2R IHC is difficult to standardise, however it provides persistent accurate results and serves a very important diagnostic tool in tertiary care referral centres where antiPLA2R offer no help in diagnosis.
Sanjeet Roy
Christian Medical College Vellore Association
Read the Original
This page is a summary of: Immunohistochemical Glomerular Expression of Phospholipase A2 Receptor in Primary and Secondary Membranous Nephropathy: A Retrospective Study in an Indian Cohort with Clinicopathological Correlations
, Nephron Extra, February 2017, Karger Publishers,
DOI: 10.1159/000453675.
You can read the full text:
Contributors
The following have contributed to this page
