Additional NO2 substitution into a 2-nitrobenzyl changes the structure and photodegradation rate.

What is it about?

This paper describes the synthesis and molecular structure determination of the title carbamate related to 2-nitrobenzyl derivatives, which are commonly used as photolytic protecting groups. We studied how the substitution position of the second NO2 substitution affects the photodegradation rate. It was found that this dinitro compound, spontaneously crystallized in organic solution, photodegrades faster than the relating mono nitro compound depending on the substitution position.

Featured Image

Why is it important?

Photodegradable protecting groups that can be easily introduced into various functional groups are in demand, so it is important to obtain compound structures that will guide the design of these molecules.

Perspectives

“

Although we have focused on changing the alpha substituent of 2-nitrobenzyl group, we plan to design more sensitive photodegradable groups by changing the number and position of both methoxy and nitro group substitutions.

”