What is it about?
This study reports the engineering and crystal structure of a monomeric variant of the hematopoietic cytokine FLT3 Ligand that is able to bind to the cognate receptor. Such a tool can be used to interrogate the assembly mechanism of extracellular complexes of FLT3 and to further explore its therapeutic targeting.
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This page is a summary of: Engineering and crystal structure of a monomeric FLT3 ligand variant, Acta Crystallographica Section F Structural Biology Communications, April 2021, International Union of Crystallography,
DOI: 10.1107/s2053230x21003289.
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