All Stories

  1. La première étape de la transmission d’un caractère épigénétique suivie par fluorescence

    Article • médecine/sciences, August 2017, EDP Sciences

    Professor Yves MELY

  2. Charge-Controlled Nanoprecipitation as a Modular Approach to Ultrasmall Polymer Nanocarriers: Making Bright and Stable Nanoparticles

    Article • ACS Nano, May 2015, American Chemical Society (ACS)

    Professor Yves MELY

  3. Internalization mechanism of neuropeptide Y bound to its Y 1 receptor investigated by high resolution microscopy

    Article • Methods and Applications in Fluorescence, May 2015, Institute of Physics Publishing

    Professor Yves MELY

  4. Fluorescence Lifetime Imaging of Membrane Lipid Order with a Ratiometric Fluorescent Probe

    Article • Biophysical Journal, May 2015, Elsevier

    Professor Yves MELY

  5. Conquering 2-Aminopurine’s Deficiencies: Highly Emissive Isomorphic Guanosine Surrogate Faithfully Monitors Guanosine Conformation and Dynamics in DNA

    Article • Journal of the American Chemical Society, March 2015, American Chemical Society (ACS)

    Professor Yves MELY

  6. Solvatochromic Nile Red Probes with FRET Quencher Reveal Lipid Order Heterogeneity in Living and Apoptotic Cells

    Article • ACS Chemical Biology, March 2015, American Chemical Society (ACS)

    Professor Yves MELY

  7. Role of the Nucleocapsid Domain in HIV-1 Gag Oligomerization and Trafficking to the Plasma Membrane: A Fluorescence Lifetime Imaging Microscopy Investigation

    Article • Journal of Molecular Biology, March 2015, Elsevier

    Professor Yves MELY

  8. Investigating the Cellular Distribution and Interactions of HIV-1 Nucleocapsid Protein by Quantitative Fluorescence Microscopy

    Article • PLoS ONE, February 2015, PLOS

    Professor Yves MELY

  9. Emission Properties of Oxyluciferin and Its Derivatives in Water: Revealing the Nature of the Emissive Species in Firefly Bioluminescence

    Article • The Journal of Physical Chemistry, February 2015, American Chemical Society (ACS)

    Professor Yves MELY

  10. Fluorogenic Squaraine Dimers with Polarity-Sensitive Folding As Bright Far-Red Probes for Background-Free Bioimaging

    Article • Journal of the American Chemical Society, January 2015, American Chemical Society (ACS)

    Dr Dominique Bonnet, Professor Yves MELY

  11. Cationic amphiphilic calixarenes to compact DNA into small nanoparticles for gene delivery

    Article • New Journal of Chemistry, January 2015, Royal Society of Chemistry

    Dr Andrey Klymchenko, Professor Yves MELY

  12. Blue fluorogenic probes for cell plasma membranes fill the gap in multicolour imaging

    Article • RSC Advances, January 2015, Royal Society of Chemistry

    Dr Andrey Klymchenko, Professor Yves MELY

  13. Monitoring HIV-1 Protein Oligomerization by FLIM FRET Microscopy

    Article • January 2015, Springer Science + Business Media

    Professor Yves MELY

  14. Nucleocapsid Protein: A Desirable Target for Future Therapies Against HIV-1

    Article • January 2015, Springer Science + Business Media

    Professor Yves MELY

  15. Creating a high impact journal for research in fluorescence

    Article • Methods and Applications in Fluorescence, December 2014, Institute of Physics Publishing

    Professor Yves MELY

  16. The HIV-1 Nucleocapsid Protein Recruits Negatively Charged Lipids To Ensure Its Optimal Binding to Lipid Membranes

    Article • Journal of Virology, November 2014, ASM Journals

    Professor Yves MELY

  17. Retrospective on the all-in-one retroviral nucleocapsid protein

    Article • Virus Research, November 2014, Elsevier

    Professor Yves MELY

  18. Role of the nucleocapsid region in HIV-1 Gag assembly as investigated by quantitative fluorescence-based microscopy

    Article • Virus Research, November 2014, Elsevier

    Professor Yves MELY

  19. Disassembly-Driven Fluorescence Turn-on of Polymerized Micelles by Reductive Stimuli in Living Cells

    Article • Chemistry - A European Journal, October 2014, Wiley

    Dr Andrey Klymchenko, Professor Yves MELY

  20. Fluorescent Amino Acid Undergoing Excited State Intramolecular Proton Transfer for Site-Specific Probing and Imaging of Peptide Interactions

    Article • The Journal of Physical Chemistry, October 2014, American Chemical Society (ACS)

    Professor Yves MELY

  21. Biodistribution of X-Ray Iodinated Contrast Agent in Nano-Emulsions Is Controlled by the Chemical Nature of the Oily Core

    Article • ACS Nano, October 2014, American Chemical Society (ACS)

    Professor Yves MELY

  22. Introduction to Fluorescence Probing of Biological Membranes

    Article • September 2014, Springer Science + Business Media

    Professor Yves MELY

  23. Functional and Structural Characterization of 2-Amino-4-phenylthiazole Inhibitors of the HIV-1 Nucleocapsid Protein with Antiviral Activity

    Article • ACS Chemical Biology, September 2014, American Chemical Society (ACS)

    Professor Yves MELY

  24. Lipid Emulsions Differentially Affect LPS-Induced Acute Monocytes Inflammation: In Vitro Effects on Membrane Remodeling and Cell Viability

    Article • Lipids, July 2014, Wiley

    Professor Yves MELY

  25. ChemInform Abstract: Fully Regiocontrolled Polyarylation of Pyridine.

    Article • ChemInform, July 2014, Wiley

    Professor Yves MELY, Dr Frederic BIHEL

  26. Dynamics of Linker Residues Modulate the Nucleic Acid Binding Properties of the HIV-1 Nucleocapsid Protein Zinc Fingers

    Article • PLoS ONE, July 2014, PLOS

    Professor Yves MELY

  27. Collective fluorescence switching of counterion-assembled dyes in polymer nanoparticles

    Article • Nature Communications, June 2014, Springer Science + Business Media

    Dr Andrey Klymchenko, Professor Yves MELY

  28. Counterion-enhanced cyanine dye loading into lipid nano-droplets for single-particle tracking in zebrafish

    Article • Biomaterials, June 2014, Elsevier

    Professor Yves MELY

  29. Comparison of the Oilseed rape mosaic virus and Tobacco mosaic virus movement proteins (MP) reveals common and dissimilar MP functions for tobamovirus spread

    Article • Virology, May 2014, Elsevier

    Professor Yves MELY

  30. Structural and functional studies of HIV-1 pre-integration complexes

    Article • BMC Infectious Diseases, May 2014, Springer Science + Business Media

    Professor Yves MELY

  31. Calixarenes and related macrocycles as gene delivery vehicles

    Article • Journal of Inclusion Phenomena and Macrocyclic Chemistry, April 2014, Springer Science + Business Media

    Professor Yves MELY

  32. 13th Conference on Methods and Applications in Fluorescence—MAF-13

    Article • Methods and Applications in Fluorescence, April 2014, Institute of Physics Publishing

    Professor Yves MELY

  33. Poly-ε-caprolactone tungsten oxide nanoparticles as a contrast agent for X-ray computed tomography

    Article • Biomaterials, March 2014, Elsevier

    Dr Andrey Klymchenko, Professor Yves MELY

  34. Fully Regiocontrolled Polyarylation of Pyridine

    Article • The Journal of Organic Chemistry, February 2014, American Chemical Society (ACS)

    Professor Yves MELY, Dr Frederic BIHEL

  35. Characterization of the structural modifications accompanying the loss of HBsAg particle immunogenicity

    Article • Vaccine, February 2014, Elsevier

    Professor Yves MELY

  36. Red Fluorescent Turn-On Ligands for Imaging and Quantifying G Protein-Coupled Receptors in Living Cells

    Article • ChemBioChem, January 2014, Wiley

    Dr Dominique Bonnet, Professor Yves MELY

  37. Rational Design of a Solvatochromic Fluorescent Uracil Analogue with a Dual-Band Ratiometric Response Based on 3-Hydroxychromone

    Article • Chemistry - A European Journal, January 2014, Wiley

    Professor Yves MELY, Dr Rachid Benhida

  38. Tuning excited-state proton transfer dynamics of a 3-hydroxychromone dye in supramolecular complexes via host–guest steric compatibility

    Article • Physical Chemistry Chemical Physics, January 2014, Royal Society of Chemistry

    Dr Semen O. Yesylevskyy, Professor Yves MELY

  39. Out-of-equilibrium biomolecular interactions monitored by picosecond fluorescence in microfluidic droplets

    Article • Lab on a Chip, January 2014, Royal Society of Chemistry

    Professor Yves MELY

  40. Imaging lipid order changes in endosome membranes of live cells by using a Nile Red-based membrane probe

    Article • RSC Advances, January 2014, Royal Society of Chemistry

    Dr Andrey Klymchenko, Professor Yves MELY

  41. Monitoring penetratin interactions with lipid membranes and cell internalization using a new hydration-sensitive fluorescent probe

    Article • Organic & Biomolecular Chemistry, January 2014, Royal Society of Chemistry

    Dr Andrey Klymchenko, Professor Yves MELY

  42. Tuning the color and photostability of perylene diimides inside polymer nanoparticles: towards biodegradable substitutes of quantum dots

    Article • Nanoscale, January 2014, Royal Society of Chemistry

    Dr Andrey Klymchenko, Professor Yves MELY

  43. A non-covalent complex of quantum dots and chlorin e6: efficient energy transfer and remarkable stability in living cells revealed by FLIM

    Article • RSC Advances, January 2014, Royal Society of Chemistry

    Dr Andrey Klymchenko, Professor Yves MELY

  44. Dual-Fluorescencel-Amino Acid Reports Insertion and Orientation of Melittin Peptide in Cell Membranes

    Article • Bioconjugate Chemistry, December 2013, American Chemical Society (ACS)

    Professor Yves MELY

  45. Celebrating our first year

    Article • Methods and Applications in Fluorescence, December 2013, Institute of Physics Publishing

    Professor Yves MELY

  46. Monitoring Membrane Properties and Apoptosis Using Membrane Probes of the 3-Hydroxyflavone Family

    Article • August 2013, Springer Science + Business Media

    Professor Yves MELY

  47. Osteogenetic Properties of Electrospun Nanofibrous PCL Scaffolds Equipped With Chitosan-Based Nanoreservoirs of Growth Factors

    Article • Macromolecular Bioscience, August 2013, Wiley

    Dr Deepak M Kalaskar, Professor Yves MELY

  48. Thermodynamically Stable Dispersions of Quantum Dots in a Nematic Liquid Crystal

    Article • Langmuir, July 2013, American Chemical Society (ACS)

    Professor Yves MELY

  49. Yves Mély and Guy Duportail (Eds.): Fluorescent methods to study biological membranes

    Article • Analytical and Bioanalytical Chemistry, May 2013, Springer Science + Business Media

    Professor Yves MELY

  50. Rational design of fluorescent membrane probes for apoptosis based on 3-hydroxyflavone

    Article • Methods and Applications in Fluorescence, May 2013, Institute of Physics Publishing

    Dr Andrey Klymchenko, Professor Yves MELY

  51. Structural and Functional Role of INI1 and LEDGF in the HIV-1 Preintegration Complex

    Article • PLoS ONE, April 2013, PLOS

    Professor Yves MELY

  52. The use of fluorescent intrabodies to detect endogenous gankyrin in living cancer cells

    Article • Experimental Cell Research, April 2013, Elsevier

    Professor Yves MELY

  53. Two photon fluorescence imaging of lipid membrane domains and potentials using advanced fluorescent probes

    Article • February 2013, SPIE

    Professor Yves MELY

  54. Welcome to Methods and Applications in Fluorescence

    Article • Methods and Applications in Fluorescence, January 2013, Institute of Physics Publishing

    Professor Yves MELY

  55. Fluorescent Methods to Study Biological Membranes

    Article • January 2013

    Professor Yves MELY

  56. Fluorescent Environment-Sensitive Dyes as Reporters of Biomolecular Interactions

    Article • January 2013, Elsevier

    Professor Yves MELY

  57. Limoniastrum guyonianum aqueous gall extract induces apoptosis in human cervical cancer cells involving p16INK4A re-expression related to UHRF1 and DNMT1 down-regulation

    Article • Journal of Experimental & Clinical Cancer Research, January 2013, Springer Science + Business Media

    Professor Yves MELY

  58. Detection of apoptosis through the lipid order of the outer plasma membrane leaflet

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, December 2012, Elsevier

    Professor Yves MELY

  59. Two-Color Fluorescent l-Amino Acid Mimic of Tryptophan for Probing Peptide–Nucleic Acid Complexes

    Article • Bioconjugate Chemistry, November 2012, American Chemical Society (ACS)

    Professor Yves MELY

  60. Comparative nucleic acid chaperone properties of the nucleocapsid protein NCp7 and Tat protein of HIV-1

    Article • Virus Research, November 2012, Elsevier

    Professor Yves MELY

  61. Use of virtual screening for discovering antiretroviral compounds interacting with the HIV-1 nucleocapsid protein

    Article • Virus Research, November 2012, Elsevier

    Professor Yves MELY

  62. The structure of HBsAg particles is not modified upon their adsorption on aluminium hydroxide gel

    Article • Vaccine, July 2012, Elsevier

    Professor Yves MELY

  63. Intrinsic Nucleic Acid Dynamics Modulates HIV-1 Nucleocapsid Protein Binding to Its Targets

    Article • PLoS ONE, June 2012, PLOS

    Professor Yves MELY

  64. A Universal Nucleoside with Strong Two-Band Switchable Fluorescence and Sensitivity to the Environment for Investigating DNA Interactions

    Article • Journal of the American Chemical Society, June 2012, American Chemical Society (ACS)

    Professor Yves MELY, Dr Rachid Benhida

  65. Sensing Micelle Hydration by Proton-Transfer Dynamics of a 3-Hydroxychromone Dye: Role of the Surfactant Headgroup and Chain Length

    Article • Langmuir, April 2012, American Chemical Society (ACS)

    Professor Yves MELY

  66. Quantification of Local Hydration at the Surface of Biomolecules Using Dual-Fluorescence Labels

    Article • The Journal of Physical Chemistry A, March 2012, American Chemical Society (ACS)

    Professor Yves MELY

  67. Lactose-ornithine bolaamphiphiles for efficient gene delivery in vitro

    Article • International Journal of Pharmaceutics, February 2012, Elsevier

    Dr Namrata Jain, Professor Yves MELY

  68. A FRET-based probe with a chemically deactivatable quencher

    Article • Chemical Communications, January 2012, Royal Society of Chemistry

    Professor Yves MELY

  69. Ab initio study of the solvent H-bonding effect on ESIPT reaction and electronic transitions of 3-hydroxychromone derivatives

    Article • Physical Chemistry Chemical Physics, January 2012, Royal Society of Chemistry

    Professor Yves MELY

  70. Dipolar 3-methoxychromones as bright and highly solvatochromic fluorescent dyes

    Article • Physical Chemistry Chemical Physics, January 2012, Royal Society of Chemistry

    Dr Andrey Klymchenko, Professor Yves MELY

  71. Highly lipophilic fluorescent dyes in nano-emulsions: towards bright non-leaking nano-droplets

    Article • RSC Advances, January 2012, Royal Society of Chemistry

    Dr Andrey Klymchenko, Professor Yves MELY

  72. A new microfluidic setup for precise control of the polymer nanoprecipitation process and lipophilic drug encapsulation

    Article • Soft Matter, January 2012, Royal Society of Chemistry

    Professor Yves MELY

  73. HIV-1 Gag Directed Assembly of Retroviral Particles Investigated by Quantitative Fluorescence Imaging

    Article • January 2012, Springer Science + Business Media

    Professor Yves MELY

  74. Comparison of α-Synuclein and Amyloid Beta Membrane Interactions

    Article • Biophysical Journal, January 2012, Elsevier

    Professor Yves MELY

  75. 3-Hydroxychromone Probes Precisely Located and Oriented in Lipid Bilayers: A Toolkit for Biomembrane Research

    Article • January 2012, Springer Science + Business Media

    Professor Yves MELY

  76. The HIV-1 Pre-Integration Complex: Structural and Functional Role of INI1 and LEDGF, Cellular Cofactors of Viral Integrase

    Article • Biophysical Journal, January 2012, Elsevier

    Professor Yves MELY

  77. A phenyl-thiadiazolylidene-amine derivative ejects zinc from retroviral nucleocapsid zinc fingers and inactivates HIV virions

    Article • Retrovirology, January 2012, Springer Science + Business Media

    Professor Yves MELY

  78. Characterization of the mechanisms of HIV-1 Vpr(52–96) internalization in cells

    Article • Biochimie, October 2011, Elsevier

    Professor Yves MELY

  79. Flexible Nature and Specific Functions of the HIV-1 Nucleocapsid Protein

    Article • Journal of Molecular Biology, July 2011, Elsevier

    Professor Yves MELY

  80. Virus-Sized DNA Nanoparticles for Gene Delivery Based on Micelles of Cationic Calixarenes

    Article • Chemistry - A European Journal, April 2011, Wiley

    Dr Namrata Jain, Professor Yves MELY

  81. Common architecture of nuclear receptor heterodimers on DNA direct repeat elements with different spacings

    Article • Nature Structural & Molecular Biology, April 2011, Springer Science + Business Media

    Professor Yves MELY

  82. The HIV-1 Gag precursor induces the recruitment of Vpr oligomers to the plasma membrane as revealed by time-resolved fluorescence imaging

    Article • February 2011, SPIE

    Professor Yves MELY

  83. Structural and Functional Role of INI1, a Cellular Cofactor of HIV-1 integrase in the Early Step of HIV Infection

    Article • Biophysical Journal, February 2011, Elsevier

    Professor Yves MELY

  84. Core functionalization of polydiacetylene micelles by a “click” reaction

    Article • Soft Matter, January 2011, Royal Society of Chemistry

    Dr Andrey Klymchenko, Professor Yves MELY

  85. Contribution of a tyrosine-based motif to cellular trafficking of wild-type and truncated NPY Y1 receptors

    Article • Cellular Signalling, January 2011, Elsevier

    Professor Yves MELY

  86. Characterizing and imaging biomembrane properties with multiparametric environment-sensitive fluorescent probes

    Article • December 2010, Institute of Electrical & Electronics Engineers (IEEE)

    Professor Yves MELY

  87. The “Phantom Effect” of the Rexinoid LG100754: Structural and Functional Insights

    Article • PLoS ONE, November 2010, PLOS

    Professor Yves MELY

  88. Structure and Behavior of Polydiacetylene-Based Micelles

    Article • Macromolecular Chemistry and Physics, November 2010, Wiley

    Professor Yves MELY

  89. Biophysical studies of the nucleic acid chaperone properties of the HIV-1 nucleocapsid protein

    Article • RNA Biology, November 2010, Taylor & Francis

    Professor Yves MELY

  90. A Family of Plasmodesmal Proteins with Receptor-Like Properties for Plant Viral Movement Proteins

    Article • PLoS Pathogens, September 2010, PLOS

    Professor Yves MELY

  91. HIV-1 viral protein r: from structure to function

    Article • Future Virology, September 2010, Future Medicine

    Professor Yves MELY

  92. Characterization of the lipid and protein organization in HBsAg viral particles by steady-state and time-resolved fluorescence spectroscopy

    Article • Biochimie, August 2010, Elsevier

    Professor Yves MELY

  93. Behavior of plant plasma membranes under hydrostatic pressure as monitored by fluorescent environment-sensitive probes

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, August 2010, Elsevier

    Professor Yves MELY

  94. Liquid ordered phase in cell membranes evidenced by a hydration-sensitive probe: Effects of cholesterol depletion and apoptosis

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, July 2010, Elsevier

    Professor Yves MELY

  95. A peptide-based fluorescent ratiometric sensor for quantitative detection of proteins

    Article • Analytical Biochemistry, June 2010, Elsevier

    Professor Yves MELY

  96. N,N′-Bis(1,2,3-thiadiazol-5-yl)benzene-1,2-diamine Targets the HIV-1 Retroviral Nucleocapsid Zinc Fingers

    Article • Antiviral Research, April 2010, Elsevier

    Professor Yves MELY

  97. The nucleocapsid protein of HIV-1 as a promising therapeutic target for antiviral drugs

    Article • HIV Therapy, March 2010, Future Medicine

    Professor Yves MELY

  98. Consequences of Isostructural Main‐Chain Modifications for the Design of Antimicrobial Foldamers: Helical Mimics of Host‐Defense Peptides Based on a Heterogeneous Amide/Urea Backbone

    Article • Angewandte Chemie International Edition, January 2010, Wiley

    Professor Yves MELY

  99. Fluorescent protein recruitment assay for demonstration and analysis ofin vivoprotein interactions in plant cells and its application toTobacco mosaic virusmovement protein

    Article • The Plant Journal, January 2010, Wiley

    Professor Yves MELY

  100. Fluorescence Lifetime Tuning—A Novel Approach to Study Flip-Flop Kinetics in Supported Phospholipid Bilayers

    Article • Journal of Fluorescence, December 2009, Springer Science + Business Media

    Professor Yves MELY

  101. Consequences of Isostructural Main‐Chain Modifications for the Design of Antimicrobial Foldamers: Helical Mimics of Host‐Defense Peptides Based on a Heterogeneous Amide/Urea Backbone

    Article • Angewandte Chemie, December 2009, Wiley

    Professor Yves MELY

  102. Unusually slow proton transfer dynamics of a 3-hydroxychromone dye in protic solvents

    Article • Photochemical & Photobiological Sciences, November 2009, Springer Science + Business Media

    Professor Yves MELY

  103. Efficient Synthesis of Ratiometric Fluorescent Nucleosides Featuring 3-Hydroxychromone Nucleobases

    Article • Tetrahedron, September 2009, Elsevier

    Professor Yves MELY, Dr Rachid Benhida

  104. 3-Hydroxybenzo[g]quinolones: dyes with red-shifted absorption and highly resolved dual emission

    Article • Tetrahedron Letters, August 2009, Elsevier

    Professor Yves MELY

  105. Identification by high throughput screening of small compounds inhibiting the nucleic acid destabilization activity of the HIV-1 nucleocapsid protein

    Article • Biochimie, July 2009, Elsevier

    Professor Yves MELY

  106. Local environment perturbations in alpha1-antitrypsin monitored by a ratiometric fluorescent label

    Article • Photochemical & Photobiological Sciences, June 2009, Springer Science + Business Media

    Professor Yves MELY

  107. Monitoring Biophysical Properties of Lipid Membranes by Environment-Sensitive Fluorescent Probes

    Article • Biophysical Journal, May 2009, Elsevier

    Professor Yves MELY

  108. Visualization of lipid domains in giant unilamellar vesicles using an environment-sensitive membrane probe based on 3-hydroxyflavone

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, February 2009, Elsevier

    Professor Yves MELY

  109. Solid phase synthesis of the retro viral nucleocapsid protein NCp10 of Moloney Murine Leukaemia virus and related “zinc-fingers” in free SH forms

    Article • International journal of peptide & protein research, January 2009, Wiley

    Professor Yves MELY

  110. Improved push-pull-push E-Bodipy fluorophores for two-photon cell-imaging

    Article • Organic & Biomolecular Chemistry, January 2009, Royal Society of Chemistry

    Professor Yves MELY

  111. Combining Fluorescence Lifetime and Polarization Microscopy to Discriminate Phase Separated Domains in Giant Unilamellar Vesicles

    Article • Biophysical Journal, December 2008, Elsevier

    Professor Yves MELY

  112. Dual-Fluorescence Probe of Environment Basicity (Hydrogen Bond Accepting Ability) Displaying no Sensitivity to Polarity

    Article • Journal of Fluorescence, November 2008, Springer Science + Business Media

    Professor Yves MELY

  113. How the HIV-1 Nucleocapsid Protein Binds and Destabilises the (−)Primer Binding Site During Reverse Transcription

    Article • Journal of Molecular Biology, November 2008, Elsevier

    Professor Yves MELY

  114. Two-Photon Two-Focus Fluorescence Correlation Spectroscopy with a Tunable Distance Between the Excitation Volumes

    Article • Journal of Fluorescence, October 2008, Springer Science + Business Media

    Professor Yves MELY

  115. Liquid Ordered and Gel Phases of Lipid Bilayers: Fluorescent Probes Reveal Close Fluidity but Different Hydration

    Article • Biophysical Journal, August 2008, Elsevier

    Professor Yves MELY

  116. Inhibition of HIV-1 by a Peptide Ligand of the Genomic RNA Packaging Signal Ψ

    Article • ChemMedChem, May 2008, Wiley

    Professor Yves MELY

  117. Distinct Motifs of Neuropeptide Y Receptors Differentially Regulate Trafficking and Desensitization

    Article • Traffic, March 2008, Wiley

    Professor Yves MELY

  118. 6th International Symposium on Retroviral Nucleocapsid

    Article • Retrovirology, January 2008, Springer Science + Business Media

    Professor Yves MELY

  119. Targeting the Viral Nucleocapsid Protein in Anti-HIV-1 Therapy

    Article • Mini-Reviews in Medicinal Chemistry, January 2008, Bentham Science Publishers

    Professor Yves MELY

  120. Modulation of microtubule assembly by the HIV-1 Tat protein is strongly dependent on zinc binding to Tat

    Article • Retrovirology, January 2008, Springer Science + Business Media

    Professor Yves MELY

  121. Direct Vpr-Vpr Interaction in Cells monitored by two Photon Fluorescence Correlation Spectroscopy and Fluorescence Lifetime Imaging

    Article • Retrovirology, January 2008, Springer Science + Business Media

    Professor Yves MELY

  122. Hydrophobically modified low molecular weight chitosans as efficient and nontoxic gene delivery vectors

    Article • The Journal of Gene Medicine, January 2008, Wiley

    Professor Yves MELY

  123. Investigating the Mechanism of the Nucleocapsid Protein Chaperoning of the Second Strand Transfer during HIV-1 DNA Synthesis

    Article • Journal of Molecular Biology, December 2007, Elsevier

    Professor Yves MELY

  124. The Single-Finger Nucleocapsid Protein of Moloney Murine Leukemia Virus Binds and Destabilizes the TAR Sequences of HIV-1 but Does Not Promote Efficiently Their Annealing †

    Article • Biochemistry, December 2007, American Chemical Society (ACS)

    Professor Yves MELY

  125. Tuning excited state intramolecular proton transfer in 3-hydroxyflavone derivative by reaction of its isothiocyanate group with an amine

    Article • Journal of Photochemistry and Photobiology A Chemistry, December 2007, Elsevier

    Professor Yves MELY

  126. Sensing of adenosine-5′-triphosphate anion in aqueous solutions and mitochondria by a fluorescent 3-hydroxyflavone dye

    Article • Analytical Biochemistry, October 2007, Elsevier

    Professor Yves MELY

  127. Modulation of Excited-State Intramolecular Proton Transfer by Viscosity in Protic Media

    Article • The Journal of Physical Chemistry A, October 2007, American Chemical Society (ACS)

    Professor Yves MELY

  128. Steric Control of the Excited-State Intramolecular Proton Transfer in 3-Hydroxyquinolones:  Steady-State and Time-Resolved Fluorescence Study

    Article • The Journal of Physical Chemistry A, September 2007, American Chemical Society (ACS)

    Professor Yves MELY

  129. Molecular Mechanism of the Zn2+-Induced Folding of the Distal CCHC Finger Motif of the HIV-1 Nucleocapsid Protein

    Article • Biophysical Journal, July 2007, Elsevier

    Professor Yves MELY

  130. Conjugation of a New Two-Photon Fluorophore to Poly(ethylenimine) for Gene Delivery Imaging

    Article • Bioconjugate Chemistry, May 2007, American Chemical Society (ACS)

    Professor Yves MELY, Professor patrice l baldeck

  131. Effects of polar protic solvents on dual emissions of 3-hydroxychromones

    Article • Journal of Chemical Sciences, March 2007, Springer Science + Business Media

    Professor Yves MELY

  132. Fluorescent Biomembrane Probe for Ratiometric Detection of Apoptosis

    Article • Journal of the American Chemical Society, February 2007, American Chemical Society (ACS)

    Professor Yves MELY

  133. Fluorescent dyes undergoing intramolecular proton transfer with improved sensitivity to surface charge in lipid bilayers

    Article • Photochemical & Photobiological Sciences, January 2007, Springer Science + Business Media

    Professor Yves MELY

  134. Convenient Method To Access New 4,4-Dialkoxy- and 4,4-Diaryloxy-diaza- s -indacene Dyes:  Synthesis and Spectroscopic Evaluation

    Article • The Journal of Organic Chemistry, January 2007, American Chemical Society (ACS)

    Dr Dominique Bonnet, Professor Yves MELY

  135. Cell-permeant cytoplasmic blue fluorophores optimized for in vivo two-photon microscopy with low-power excitation

    Article • Microscopy Research and Technique, January 2007, Wiley

    Professor Yves MELY, Professor patrice l baldeck

  136. Properties, Functions, and Drug Targeting of the Multifunctional Nucleocapsid Protein of the Human Immunodeficiency Virus

    Article • January 2007, Elsevier

    Professor Yves MELY

  137. Excited-State Properties and Transitions of Fluorescent 8-Vinyl Adenosine in DNA

    Article • The Journal of Physical Chemistry, December 2006, American Chemical Society (ACS)

    Professor Yves MELY

  138. Physicochemical properties of low molecular weight alkylated chitosans: A new class of potential nonviral vectors for gene delivery

    Article • Colloids and Surfaces B Biointerfaces, August 2006, Elsevier

    Professor Yves MELY

  139. A Tryptophan-Rich Hexapeptide Inhibits Nucleic Acid Destabilization Chaperoned by the HIV-1 Nucleocapsid Protein †

    Article • Biochemistry, August 2006, American Chemical Society (ACS)

    Professor Yves MELY

  140. Fluorescent Probe Based on Intramolecular Proton Transfer for Fast Ratiometric Measurement of Cellular Transmembrane Potential

    Article • The Journal of Physical Chemistry, July 2006, American Chemical Society (ACS)

    Professor Yves MELY

  141. Synthesis and Fluorescence Properties of 2-Aryl-3-hydroxyquinolones, a New Class of Dyes Displaying Dual Fluorescence.

    Article • ChemInform, May 2006, Wiley

    Professor Yves MELY

  142. During the Early Phase of HIV-1 DNA Synthesis, Nucleocapsid Protein Directs Hybridization of the TAR Complementary Sequences via the Ends of their Double-stranded Stem

    Article • Journal of Molecular Biology, March 2006, Elsevier

    Professor Yves MELY

  143. Synthesis and fluorescence properties of 2-aryl-3-hydroxyquinolones, a new class of dyes displaying dual fluorescence

    Article • Tetrahedron Letters, February 2006, Elsevier

    Professor Yves MELY

  144. Synthesis and characterization of water-soluble two-photon excited blue fluorescent chromophores for bioimaging

    Article • Photochemical & Photobiological Sciences, January 2006, Springer Science + Business Media

    Professor Yves MELY, Professor patrice l baldeck

  145. Membrane Dipole Potential as Measured by Ratiometric 3-Hydroxyflavone Fluorescence Probes: Accounting for Hydration Effects

    Article • Journal of Fluorescence, January 2006, Springer Science + Business Media

    Professor Yves MELY

  146. Investigation by fluorescence correlation spectroscopy of the chaperoning interactions of HIV-1 nucleocapsid protein with the viral DNA initiation sequences

    Article • Comptes Rendus Biologies, December 2005, Elsevier

    Professor Yves MELY

  147. Two-color fluorescent probes for imaging the dipole potential of cell plasma membranes

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, July 2005, Elsevier

    Professor Yves MELY

  148. Structural Determinants of HIV-1 Nucleocapsid Protein for cTAR DNA Binding and Destabilization, and Correlation with Inhibition of Self-primed DNA Synthesis

    Article • Journal of Molecular Biology, May 2005, Elsevier

    Professor Yves MELY

  149. Mechanism of Zinc Coordination by Point-Mutated Structures of the Distal CCHC Binding Motif of the HIV-1 NCp7 Protein

    Article • Biochemistry, April 2005, American Chemical Society (ACS)

    Professor Yves MELY

  150. The C-terminal domain of the HIV-1 regulatory protein Vpr adopts an antiparallel dimeric structure in solution via its leucine-zipper-like domain

    Article • Biochemical Journal, April 2005, Portland Press Ltd.

    Professor Yves MELY

  151. Anion Formation of 4‘-(Dimethylamino)-3-hydroxyflavone in Phosphatidylglycerol Vesicles Induced by HEPES Buffer:  A Steady-State and Time-Resolved Fluorescence Investigation

    Article • The Journal of Physical Chemistry, December 2004, American Chemical Society (ACS)

    Professor Yves MELY

  152. 7-(2-Methoxycarbonylvinyl)-3-hydroxychromones: new dyes with red shifted dual emission

    Article • Tetrahedron Letters, November 2004, Elsevier

    Professor Yves MELY

  153. Dynamics of Intermolecular Hydrogen Bonds in the Excited States of 4‘-Dialkylamino-3-hydroxyflavones. On the Pathway to an Ideal Fluorescent Hydrogen Bonding Sensor

    Article • The Journal of Physical Chemistry A, October 2004, American Chemical Society (ACS)

    Professor Yves MELY

  154. Simultaneous probing of hydration and polarity of lipid bilayers with 3-hydroxyflavone fluorescent dyes

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, October 2004, Elsevier

    Professor Yves MELY

  155. Investigation by two-photon fluorescence correlation spectroscopy of the interaction of the nucleocapsid protein of HIV-1 with hairpin loop DNA sequences

    Article • September 2004, SPIE

    Professor Yves MELY

  156. HIV-1 Nucleocapsid Protein Binds to the Viral DNA Initiation Sequences and Chaperones their Kissing Interactions

    Article • Journal of Molecular Biology, September 2004, Elsevier

    Professor Yves MELY

  157. H-bond sensing with 3-hydroxyflavones: steady-state and time-resolved fluorescence studies

    Article • September 2004, SPIE

    Professor Yves MELY

  158. Multiparametric fluorescence probing of nanoscale compositions and biological systems

    Article • September 2004, SPIE

    Professor Yves MELY

  159. Oxidisable cationic detergent for gene therapy: condensation of DNA and interaction with model membranes

    Article • June 2004, Springer Science + Business Media

    Professor Yves MELY

  160. Oxidisable cationic detergent for gene therapy: condensation of DNA and interaction with model membranes

    Article • June 2004, Springer Science + Business Media

    Professor Yves MELY

  161. Structure of the His44 → Ala Single Point Mutant of the Distal Finger Motif of HIV-1 Nucleocapsid Protein:  A Combined NMR, Molecular Dynamics Simulation, and Fluorescence Study †

    Article • Biochemistry, June 2004, American Chemical Society (ACS)

    Professor Yves MELY

  162. Role of the Structure of the Top Half of HIV-1 cTAR DNA on the Nucleic Acid Destabilizing Activity of the Nucleocapsid Protein NCp7

    Article • Journal of Molecular Biology, May 2004, Elsevier

    Professor Yves MELY

  163. Bimodal Distribution and Fluorescence Response of Environment-Sensitive Probes in Lipid Bilayers

    Article • Biophysical Journal, May 2004, Elsevier

    Professor Yves MELY

  164. Dependence of the cellular internalization and transfection efficiency on the structure and physicochemical properties of cationic detergent/DNA/liposomes

    Article • The Journal of Gene Medicine, April 2004, Wiley

    Professor Yves MELY

  165. Time-Resolved Fluorescence Allows Selective Monitoring of Trp30 Environmental Changes in the Seven-Trp-Containing Human Pancreatic Lipase †

    Article • Biochemistry, November 2003, American Chemical Society (ACS)

    Professor Yves MELY

  166. Picosecond Time-Resolved Fluorescence Studies Are Consistent with Reversible Excited-State Intramolecular Proton Transfer in 4‘-(Dialkylamino)-3-hydroxyflavones

    Article • The Journal of Physical Chemistry A, November 2003, American Chemical Society (ACS)

    Professor Yves MELY

  167. Poly(ADP-ribose) Polymerase-1 Dimerizes at a 5‘ Recessed DNA End in Vitro :  A Fluorescence Study †

    Article • Biochemistry, October 2003, American Chemical Society (ACS)

    Professor Yves MELY

  168. Intracellular dynamics of the gene delivery vehicle polyethylenimine during transfection: investigation by two-photon fluorescence correlation spectroscopy

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, October 2003, Elsevier

    Professor Yves MELY

  169. Impact of the Terminal Bulges of HIV-1 cTAR DNA on its Stability and the Destabilizing Activity of the Nucleocapsid Protein NCp7

    Article • Journal of Molecular Biology, April 2003, Elsevier

    Professor Yves MELY

  170. Monitoring of the Formation and Dissociation of Polyethylenimine/DNA Complexes by Two Photon Fluorescence Correlation Spectroscopy

    Article • Biophysical Journal, March 2003, Elsevier

    Professor Yves MELY

  171. Conformational change in elastase following complexation with alpha1-proteinase inhibitor: a CD investigation

    Article • Biochemical Journal, February 2003, Portland Press Ltd.

    Professor Yves MELY

  172. Destabilization of the HIV-1 Complementary Sequence of TAR by the Nucleocapsid Protein Through Activation of Conformational Fluctuations

    Article • Journal of Molecular Biology, February 2003, Elsevier

    Professor Yves MELY

  173. Excitonic Heterodimer Formation in an HIV-1 Oligonucleotide Labeled with a Donor-Acceptor Pair Used for Fluorescence Resonance Energy Transfer

    Article • Biophysical Journal, January 2003, Elsevier

    Professor Yves MELY

  174. Investigation of the Stability of Dimeric Cationic Surfactant/DNA Complexes and Their Interaction with Model Membrane Systems

    Article • Langmuir, December 2002, American Chemical Society (ACS)

    Professor Yves MELY

  175. Structure and Dynamics of Condensed DNA Probed by 1,1‘-(4,4,8,8-Tetramethyl-4,8-diazaundecamethylene)bis[4-[[3- methylbenz-1,3-oxazol-2-yl]methylidine]-1,4-dihydroquinolinium] Tetraiodide Fluorescence

    Article • Biochemistry, December 2002, American Chemical Society (ACS)

    Professor Yves MELY

  176. Novel Two-Band Ratiometric Fluorescence Probes with Different Location and Orientation in Phospholipid Membranes

    Article • Chemistry & Biology, November 2002, Elsevier

    Professor Yves MELY

  177. HIV-1 nucleocapsid protein activates transient melting of least stable parts of the secondary structure of TAR and its complementary sequence

    Article • Journal of Molecular Biology, March 2002, Elsevier

    Professor Yves MELY

  178. Effects of temperature on the dynamic behaviour of the HIV-1 nucleocapsid NCp7 and its DNA complex

    Article • Journal of Molecular Biology, February 2002, Elsevier

    Professor Yves MELY

  179. Neutral fluorescence probe with strong ratiometric response to surface charge of phospholipid membranes

    Article • FEBS Letters, November 2001, Wiley

    Professor Yves MELY

  180. Role of endocytosis in the transfection of L929 fibroblasts by polyethylenimine/DNA complexes

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, September 2001, Elsevier

    Professor Yves MELY

  181. DNA condensation by an oxidizable cationic detergent. Interactions with lipid vesicles

    Article • Chemistry and Physics of Lipids, May 2001, Elsevier

    Professor Yves MELY

  182. Time-Resolved Fluorescence Investigation of the Human Immunodeficiency Virus Type 1 Nucleocapsid Protein: Influence of the Binding of Nucleic Acids

    Article • Biophysical Journal, March 1999, Elsevier

    Professor Yves MELY

  183. Properties and growth mechanism of the ordered aggregation of a model RNA by the HIV-1 nucleocapsid protein: An electron microscopy investigation

    Article • Biopolymers, March 1998, Wiley

    Professor Yves MELY

  184. Properties and growth mechanism of the ordered aggregation of a model RNA by the HIV‐1 nucleocapsid protein: An electron microscopy investigation

    Article • Biopolymers, March 1998, Wiley

    Professor Yves MELY

  185. Mapping the Suramin-Binding Sites of Human Neutrophil Elastase:  Investigation by Fluorescence Resonance Energy Transfer and Molecular Modeling †

    Article • Biochemistry, December 1997, American Chemical Society (ACS)

    Professor Yves MELY

  186. A comparison of the fluorescence properties of TMA-DPH as a probe for plasma membrane and for endocytic membrane

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, October 1995, Elsevier

    Professor Yves MELY

  187. Structure and tRNAPhe-Binding Properties of the Zinc Finger Motifs of HIV-1 Nucleocapsid Protein

    Article • January 1994, Springer Science + Business Media

    Professor Yves MELY

  188. RNA hybridization activities of the nucleocapsid protein NCp7 of HIV-1 is restricted to amino acids flanking the finger domains

    Article • January 1993, Springer Science + Business Media

    Professor Yves MELY

  189. Influence of the N- and C-terminal chains on the zinc-binding and conformational properties of the central zinc-finger structure of Moloney murine leukaemia virus nucleocapsid protein: a steady-state and time-resolved fluorescence study

    Article • Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, January 1993, Elsevier

    Professor Yves MELY

  190. Heparin-induced conformational change and activation of mucus proteinase inhibitor

    Article • Biochemistry, September 1992, American Chemical Society (ACS)

    Professor Yves MELY

  191. Investigation of zinc-binding affinities of moloney murine leukemia virus nucleocapsid protein and its related zinc finger and modified peptides

    Article • Biopolymers, June 1991, Wiley

    Professor Yves MELY

  192. Intra- and Interchain Disulfide Bond Generation in S100b Protein

    Article • Journal of Neurochemistry, October 1990, Wiley

    Professor Yves MELY

  193. Structural and ion-binding properties of an S100b protein mixed disulfide: Comparison with the reappraised native S100b protein properties

    Article • Archives of Biochemistry and Biophysics, May 1990, Elsevier

    Professor Yves MELY

  194. Inhibition of Monoamine Oxidase Selectively in Brain Monoamine Nerves Using the Bioprecursor (E-?-Fluoromethylene-m-Tyrosine (MDL 72394), a Substrate for Aromatic L-Amino Acid Decarboxylase

    Article • Journal of Neurochemistry, December 1985, Wiley

    Professor Yves MELY

  195. The effect of plasma gelsolin on actin filaments Ca2+-dependency of the capping and severing activities

    Article • Biochemical and Biophysical Research Communications, September 1985, Elsevier

    Professor Yves MELY

  196. Chapter 5. Fluorescence Techniques to Characterise Ligand Binding to Proteins

    Article • Royal Society of Chemistry

    Professor Yves MELY

  197. Dynamics of DNA and Portein-DNA Complexes Viewed Through Time-Domain Fluorescence

    Article • Springer Science + Business Media

    Professor Yves MELY