All Stories

  1. ChemInform Abstract: Microwave-Assisted Cycloaddition Reactions in Carbo- and Heterocyclic Chemistry

    Article • ChemInform, February 2015, Wiley

    Dr Rachid Benhida

  2. Development of environmentally sensitive fluorescent and dual emissive deoxyuridine analogues

    Article • RSC Advances, January 2015, Royal Society of Chemistry

    Dr Rachid Benhida

  3. Efficient and selective azidation of per-O-acetylated sugars using ultrasound activation: application to the one-pot synthesis of 1,2,3-triazole glycosides

    Article • New Journal of Chemistry, January 2015, Royal Society of Chemistry

    Dr Rachid Benhida

  4. FeCl3-promoted and ultrasound-assisted synthesis of resveratrol O-derived glycoside analogs

    Article • Ultrasonics Sonochemistry, January 2015, Elsevier

    Dr Rachid Benhida

  5. Microwave-assisted Cycloaddition Reactions in Carbo- and Heterocyclic Chemistry

    Article • Current Organic Chemistry, April 2014, Bentham Science Publishers

    Dr Rachid Benhida

  6. Targeting the Production of Oncogenic MicroRNAs with Multimodal Synthetic Small Molecules

    Article • ACS Chemical Biology, March 2014, American Chemical Society (ACS)

    Dr Rachid Benhida

  7. Rational Design of a Solvatochromic Fluorescent Uracil Analogue with a Dual-Band Ratiometric Response Based on 3-Hydroxychromone

    Article • Chemistry - A European Journal, January 2014, Wiley

    Professor Yves MELY, Dr Rachid Benhida

  8. Artificial Nucleobase-Amino Acid Conjugates: A New Class of TAR RNA Binding Agents

    Article • Chemistry - A European Journal, January 2014, Wiley

    Dr Rachid Benhida

  9. Can we use the epigenetic bioactivity of caloric restriction and phytochemicals to promote healthy ageing?

    Article • MedChemComm, January 2014, Royal Society of Chemistry

    Dr Rachid Benhida

  10. Natural Polyphenols as Potent Inhibitors of DNA Methyltransferases

    Article • January 2014, Elsevier

    Dr Rachid Benhida

  11. ChemInform Abstract: Sono-Transition-Metal Catalysis of One-Pot Three-Step Synthesis of Glycosyl-1,2,3-triazoles.

    Article • ChemInform, September 2013, Wiley

    Dr Rachid Benhida

  12. ChemInform Abstract: Microwave-Assisted Cycloaddition Reactions

    Article • ChemInform, July 2013, Wiley

    Dr Rachid Benhida

  13. Recent Advances in Drug Design of Epidermal Growth Factor Receptor Inhibitors

    Article • Current Medicinal Chemistry, April 2013, Bentham Science Publishers

    Dr Rachid Benhida

  14. Microwave-Assisted Cycloaddition Reactions

    Article • February 2013, Wiley

    Dr Rachid Benhida

  15. Sono-Transition-Metal Catalysis of One-Pot Three-Step Synthesis of Glycosyl-1,2,3-triazoles

    Article • Synthetic Communications, January 2013, Taylor & Francis

    Dr Rachid Benhida

  16. Ultrasound-assisted one-pot synthesis of anti-CML nucleosides featuring 1,2,3-triazole nucleobase under iron-copper catalysis

    Article • Ultrasonics Sonochemistry, November 2012, Elsevier

    Dr Rachid Benhida

  17. A Universal Nucleoside with Strong Two-Band Switchable Fluorescence and Sensitivity to the Environment for Investigating DNA Interactions

    Article • Journal of the American Chemical Society, June 2012, American Chemical Society (ACS)

    Professor Yves MELY, Dr Rachid Benhida

  18. Sequence-Specific Base Pair Mimics Are Efficient Topoisomerase IB Inhibitors

    Article • Biochemistry, January 2012, American Chemical Society (ACS)

    Dr Rachid Benhida

  19. Small molecules DNAmethyltransferasesinhibitors

    Article • MedChemComm, January 2012, Royal Society of Chemistry

    Dr Rachid Benhida

  20. ChemInform Abstract: A Mild and Efficient Protocol for the Protection of 3-Hydroxychromones under Phase-Transfer Catalysis.

    Article • ChemInform, October 2011, Wiley

    Dr Rachid Benhida

  21. A Mild and Efficient Protocol for the Protection of 3-Hydroxychromones Under Phase-Transfer Catalysis

    Article • Synthesis, May 2011, Thieme Publishing Group

    Dr Rachid Benhida

  22. ChemInform Abstract: Targeting DNA Base Pair Mismatch with Artificial Nucleobases. Advances and Perspectives in Triple Helix Strategy

    Article • ChemInform, March 2011, Wiley

    Dr Rachid Benhida

  23. Targeting DNA base pair mismatch with artificial nucleobases. Advances and perspectives in triple helix strategy

    Article • Organic & Biomolecular Chemistry, January 2011, Royal Society of Chemistry

    Dr Rachid Benhida

  24. ChemInform Abstract: Syntheses of α-Substituted Cyclohexenones by Thermolysis of Tertiary Ketosulfoxides.

    Article • ChemInform, August 2010, Wiley

    Dr Rachid Benhida

  25. ChemInform Abstract: N-Alkylated Derivatives of 4-Nitroimidazole: Synthesis by Radical Chemistry (SRN1) and Functionalization.

    Article • ChemInform, August 2010, Wiley

    Dr Rachid Benhida

  26. ChemInform Abstract: N-1 Oxidation of Adenine Substituted at N-9 by an Olefinic Chain.

    Article • ChemInform, August 2010, Wiley

    Dr Rachid Benhida

  27. ChemInform Abstract: A Highly Selective and Efficient Access to N-9 Alkylated Purine Derivatives via Radical SRN1 Chemistry.

    Article • ChemInform, August 2010, Wiley

    Dr Rachid Benhida

  28. ChemInform Abstract: N-Alkylated Purine Derivatives. Synthesis by SRN1 Reaction and Transformation of Functional Groups.

    Article • ChemInform, August 2010, Wiley

    Dr Rachid Benhida

  29. ChemInform Abstract: Synthesis of Novel Functionalized Olefins via Fragmentation of SRN1 Products with a Cyclanone β-Ester Subunit.

    Article • ChemInform, August 2010, Wiley

    Dr Rachid Benhida

  30. ChemInform Abstract: New and Straightforward Access to Olefins, Butenolides and β- Nitro γ-Butyrolactones from Precursors Obtained via SRN1 Reactions.

    Article • ChemInform, August 2010, Wiley

    Dr Rachid Benhida

  31. ChemInform Abstract: A Convenient Synthesis of 1-Ethoxymethyl-5-nitro-6-substituted Uracils.

    Article • ChemInform, August 2010, Wiley

    Dr Rachid Benhida

  32. ChemInform Abstract: Synthesis and Anti-HIV Activity of Novel N-1 Side Chain-Modified Analogues of 1-((2-Hydroxyethoxy)methyl)-6-(phenylthio)thymine (HEPT).

    Article • ChemInform, August 2010, Wiley

    Dr Rachid Benhida

  33. ChemInform Abstract: First Total Synthesis of Fungerin an Antifungal Alkaloid from Fusarium sp.

    Article • ChemInform, June 2010, Wiley

    Dr Rachid Benhida

  34. ChemInform Abstract: Incorporation of Serinol-Derived Acyclic Nucleoside Analogues into Oligonucleotides: Influence on Duplex and Triplex Formation.

    Article • ChemInform, June 2010, Wiley

    Dr Rachid Benhida

  35. ChemInform Abstract: A Mild and Effective Iodination Method Using Iodine in the Presence of Bis-(trifluoroacetoxy)iodobenzene.

    Article • ChemInform, June 2010, Wiley

    Dr Rachid Benhida

  36. ChemInform Abstract: Synthesis of 6-Allyl and 6-Heteroarylindoles by Palladium-Catalyzed Stille Cross-Coupling Reaction.

    Article • ChemInform, June 2010, Wiley

    Dr Rachid Benhida

  37. ChemInform Abstract: Efficient Stereoselective Synthesis of New C-Nucleosides via Intramolecular Mitsunobu Cyclization

    Article • ChemInform, June 2010, Wiley

    Dr Rachid Benhida

  38. ChemInform Abstract: Incorporation of a Novel Nucleobase Allows Stable Oligonucleotide-Directed Triple Helix Formation at the Target Sequence Containing a Purine×Pyrimidine Interruption.

    Article • ChemInform, May 2010, Wiley

    Dr Rachid Benhida

  39. ChemInform Abstract: Reactivity of 1,1′-Thiocarbonyldiimidazole with Glycosides: A Novel and Efficient Glycosidic Activation.

    Article • ChemInform, May 2010, Wiley

    Dr Rachid Benhida

  40. ChemInform Abstract: Bicyclic Anti-VZV Nucleosides: Thieno Analogues Retain Full Antiviral Activity.

    Article • ChemInform, May 2010, Wiley

    Dr Rachid Benhida

  41. ChemInform Abstract: Stereocontrolled Synthesis of Heterocyclic C-Nucleosides. Protecting Group Effect and Molecular Modeling Studies.

    Article • ChemInform, May 2010, Wiley

    Dr Rachid Benhida

  42. Microwave-Assisted and Efficient Solvent-free Knoevenagel Condensation. A Sustainable Protocol Using Porous Calcium Hydroxyapatite as Catalyst

    Article • Molecules, February 2010, MDPI AG

    Dr Rachid Benhida

  43. Design of novel RNA ligands that bind stem–bulge HIV-1 TAR RNA

    Article • Chemical Communications, January 2010, Royal Society of Chemistry

    Dr Rachid Benhida

  44. ChemInform Abstract: Tandem Azide—Alkyne 1,3-Dipolar Cycloaddition/Electrophilic Addition: A Concise Three-Component Route to 4,5-Disubstituted Triazolyl-Nucleosides.

    Article • ChemInform, December 2009, Wiley

    Dr Rachid Benhida

  45. Efficient Synthesis of Ratiometric Fluorescent Nucleosides Featuring 3-Hydroxychromone Nucleobases

    Article • Tetrahedron, September 2009, Elsevier

    Professor Yves MELY, Dr Rachid Benhida

  46. Tandem Azide-Alkyne 1,3-Dipolar Cycloaddition/Electrophilic Addition: A Concise Three-Component Route to 4,5-Disubstituted Triazolyl-Nucleosides

    Article • Synlett, July 2009, Thieme Publishing Group

    Dr Rachid Benhida

  47. From Intriguing Reactivity of 2-Bromothiophene to the First Synthesis of C1′-Disubstituted C-Nucleosides

    Article • Synlett, January 2009, Thieme Publishing Group

    Dr Rachid Benhida

  48. A stereo- and regio-controlled synthesis of bromothiophenyl C-nucleosides. Tandem bromination-ribosylation via halogen dance process

    Article • Tetrahedron Letters, October 2008, Elsevier

    Dr Rachid Benhida

  49. Friedel–Crafts and modified Vorbrüggen ribosylation. A short synthesis of aryl and heteroaryl-C-nucleosides

    Article • Tetrahedron Letters, June 2008, Elsevier

    Dr Rachid Benhida

  50. Efficient Synthesis of α- and β-2′-Deoxy-heteroaryl- C -nucleosides

    Article • Synlett, May 2008, Thieme Publishing Group

    Dr Rachid Benhida

  51. ChemInform Abstract: Efficient Synthesis and in vitro Cytostatic Activity of 4-Substituted Triazolyl-Nucleosides.

    Article • ChemInform, March 2008, Wiley

    Dr Rachid Benhida

  52. Efficient synthesis and in vitro cytostatic activity of 4-substituted triazolyl-nucleosides

    Article • Bioorganic & Medicinal Chemistry Letters, December 2007, Elsevier

    Dr Rachid Benhida

  53. An efficient one-step regiospecific synthesis of novel isoxazolines and isoxazoles of N-substituted saccharin derivatives through solvent-free microwave-assisted [3+2] cycloaddition

    Article • Tetrahedron Letters, January 2007, Elsevier

    Dr Rachid Benhida

  54. A Highly Efficient Microwave-Assisted Solvent-Free Synthesis of α- and β-2′-Deoxy-1,2,3-triazolyl-nucleosides.

    Article • ChemInform, October 2006, Wiley

    Dr Rachid Benhida

  55. A highly efficient microwave-assisted solvent-free synthesis of α- and β-2′-deoxy-1,2,3-triazolyl-nucleosides

    Article • Tetrahedron Letters, July 2006, Elsevier

    Dr Rachid Benhida

  56. Synthesis and in vitro antileishmanial activity of 5-substituted-2′-deoxyuridine derivatives

    Article • Bioorganic Chemistry, December 2005, Elsevier

    Dr Rachid Benhida

  57. Synthesis of Mono- and Polyhydroxylated Cyclobutane Nucleoside Analogues.

    Article • ChemInform, November 2005, Wiley

    Dr Rachid Benhida

  58. First Example of Base-Promoted Tandem Alkylation—Bromination of 2-Bromothiophene via Halogen Dance Process: A Remarkable Temperature Effect.

    Article • ChemInform, September 2005, Wiley

    Dr Rachid Benhida

  59. Synthesis of mono- and polyhydroxylated cyclobutane nucleoside analogs

    Article • Tetrahedron, August 2005, Elsevier

    Dr Rachid Benhida

  60. The ‘fully protected backbone’ approach as a versatile tool for a new solid-phase PNA synthesis strategy

    Article • Tetrahedron Letters, June 2005, Elsevier

    Dr Gregory Upert, Dr Rachid Benhida

  61. First example of base-promoted tandem alkylation–bromination of 2-bromothiophene via halogen dance process: a remarkable temperature effect

    Article • Tetrahedron Letters, May 2005, Elsevier

    Dr Rachid Benhida

  62. Ultrasound-Accelerated Aromatization of trans- and cis-Pyrazolines under Heterogeneous Conditions Using Claycop.

    Article • ChemInform, September 2004, Wiley

    Dr Rachid Benhida

  63. Efficient synthesis of extended guanine analogues designed for recognition of an A·T inverted base pair in triple helix based-strategy

    Article • Tetrahedron Letters, August 2004, Elsevier

    Dr Rachid Benhida

  64. Ultrasound-accelerated aromatisation of trans- and cis-pyrazolines under heterogeneous conditions using claycop

    Article • Tetrahedron Letters, May 2004, Elsevier

    Dr Rachid Benhida

  65. Synthesis and Triplex Binding Properties of Oligonucleotides Containing a Novel Nucleobase

    Article • ChemInform, February 2004, Wiley

    Dr Rachid Benhida

  66. Synthesis and Studies of Modified Oligonucleotides-Directed Triple Helix Formation at the Purine-Pyrimidine Interrupted Site

    Article • ChemInform, February 2004, Wiley

    Dr Rachid Benhida

  67. A Short and Efficient Synthesis of 2′-Deoxybenzo- and Pyridoimidazole C-Nucleosides.

    Article • ChemInform, November 2003, Wiley

    Dr Rachid Benhida

  68. Synthesis and Studies of Modified Oligonucleotides- Directed Triple Helix Formation at the Purine-Pyrimidine Interrupted Site

    Article • Nucleosides Nucleotides & Nucleic Acids, October 2003, Taylor & Francis

    Dr Rachid Benhida

  69. Synthesis and Triplex Binding Properties of Oligonucleotides Containing a Novel Nucleobase

    Article • Nucleosides Nucleotides & Nucleic Acids, October 2003, Taylor & Francis

    Dr Rachid Benhida

  70. A short and efficient synthesis of 2′-deoxybenzo- and pyridoimidazole C-nucleosides

    Article • Tetrahedron Letters, July 2003, Elsevier

    Dr Rachid Benhida

  71. A Short and Highly Stereoselective Synthesis of α-(2-Aminothiazolyl)-C-nucleosides.

    Article • ChemInform, June 2003, Wiley

    Dr Rachid Benhida

  72. A short and highly stereoselective synthesis of α-(2-aminothiazolyl)-C-nucleosides

    Article • Tetrahedron Letters, March 2003, Elsevier

    Dr Rachid Benhida

  73. A Short Synthesis of Aspergillamide B. The Marine Natural Product from Aspergillus sp.

    Article • ChemInform, January 2003, Wiley

    Dr Rachid Benhida

  74. Synthesis, Incorporation into Triplex-Forming Oligonucleotide, and Binding Properties of a Novel 2‘-Deoxy- C -Nucleoside Featuring a 6-(Thiazolyl-5)benzimidazole Nucleobase

    Article • Organic Letters, November 2002, American Chemical Society (ACS)

    Dr Rachid Benhida

  75. A short synthesis of aspergillamide B. The marine natural product from Aspergillus sp.

    Article • Tetrahedron Letters, October 2002, Elsevier

    Dr Rachid Benhida

  76. Stereocontrolled Synthesis of Heterocyclic C-Nucleosides. Protecting Group Effect and Molecular Modeling Studies

    Article • The Journal of Organic Chemistry, May 2002, American Chemical Society (ACS)

    Dr Rachid Benhida

  77. Binding properties of oligonucleotides containing a modified 2′-deoxyuridine with a thymine ended linker to pair with 2′-deoxyadenosine

    Article • Bioorganic & Medicinal Chemistry Letters, March 2002, Elsevier

    Dr Rachid Benhida

  78. Reactivity of 1,1′-thiocarbonyldiimidazole with glycosides: a novel and efficient glycosidic activation

    Article • Tetrahedron Letters, January 2002, Elsevier

    Dr Rachid Benhida

  79. Bicyclic anti-VZV nucleosides: Thieno analogues retain full antiviral activity

    Article • Bioorganic & Medicinal Chemistry Letters, September 2001, Elsevier

    Dr Rachid Benhida

  80. ChemInform Abstract: Efficient Stereocontrolled Synthesis of 2-Benzimidazolyl- and 2-Indolyl-C-nucleosides.

    Article • ChemInform, May 2001, Wiley

    Dr Rachid Benhida

  81. ChemInform Abstract: DNA Triplex Structures Are Stabilized by the Incorporation of 3′-endo Blocked Pyrimidine Nucleosides in the Hoogsteen Strand.

    Article • ChemInform, January 2001, Wiley

    Dr Rachid Benhida

  82. Incorporation of a novel nucleobase allows stable oligonucleotide-directed triple helix formation at the target sequence containing a purine·pyrimidine interruption

    Article • Chemical Communications, January 2001, Royal Society of Chemistry

    Dr Rachid Benhida

  83. Efficient stereocontrolled synthesis of 2-benzimidazolyl- and 2-indolyl-C-nucleosides

    Article • Tetrahedron Letters, January 2001, Elsevier

    Dr Rachid Benhida

  84. DNA triplex structures are stabilized by the incorporation of 3′-endo blocked pyrimidine nucleosides in the hoogsteen strand

    Article • Bioorganic & Medicinal Chemistry Letters, October 2000, Elsevier

    Dr Rachid Benhida

  85. ChemInform Abstract: Selective N-Trifluoroacetylation of ortho-Arylenediamines under Ultrasound

    Article • ChemInform, September 2000, Wiley

    Dr Rachid Benhida

  86. N-Trifluoroacétylation sélective d'ortho-arylènediamines sous ultrasons

    Article • Tetrahedron Letters, June 2000, Elsevier

    Dr Rachid Benhida

  87. NMR recognition studies of C·G base pairs by new easily accessible heterobicyclic systems

    Article • Tetrahedron Letters, November 1999, Elsevier

    Dr Rachid Benhida

  88. Synthesis of 6-allyl and 6-heteroarylindoles by palladium catalyzed Stille cross-coupling reaction

    Article • Tetrahedron Letters, July 1999, Elsevier

    Dr Rachid Benhida

  89. NMR Studies of Triplex Formation - Recognition of C•G Base Pairs by New Heterocyclic Systems

    Article • Nucleosides and Nucleotides, June 1999, Taylor & Francis

    Dr Rachid Benhida

  90. Efficient Stereoselective Synthesis of New C-Nucleosides via Intramolecular Mitsunobu Cyclization

    Article • Nucleosides and Nucleotides, April 1999, Taylor & Francis

    Dr Rachid Benhida

  91. Novel 2′-deoxycytidine analogues as pH independent substitutes of protonated cytosines in triple helix forming oligonucleotides

    Article • Tetrahedron Letters, January 1999, Elsevier

    Dr Rachid Benhida

  92. A mild and effective iodination method using iodine in the presence of bis-(trifluoroacetoxy)iodobenzene

    Article • Tetrahedron Letters, September 1998, Elsevier

    Dr Rachid Benhida

  93. First total synthesis of fungerin an antifungal alkaloid from Fusarium sp.

    Article • Tetrahedron Letters, August 1998, Elsevier

    Dr Rachid Benhida

  94. Incorporation of serinol derived acyclic nucleoside analogues into oligonucleotides: Influence on duplex and triplex formation

    Article • Tetrahedron Letters, August 1998, Elsevier

    Dr Rachid Benhida

  95. Synthesis and Anti-HIV Activity of Novel N-1 Side Chain-Modified Analogs of 1-[(2-Hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT)

    Article • Journal of Medicinal Chemistry, June 1997, American Chemical Society (ACS)

    Dr Rachid Benhida

  96. A convenient synthesis of 1-ethoxymethyl-5-nitro-6-substituted uracils

    Article • Tetrahedron Letters, February 1996, Elsevier

    Dr Rachid Benhida

  97. Bromoalkoxy Addition on N-Azolyl Olefins

    Article • Chemistry Letters, March 1995, The Chemical Society of Japan

    Dr Rachid Benhida

  98. Selective N1-Alkylation of Pyrimidine BasesviaRadical (SRN1) Mechanism

    Article • Nucleosides and Nucleotides, June 1994, Taylor & Francis

    Dr Rachid Benhida

  99. A Highly Selective and Efficient Access to N-9 Alkylated Purine DerivativesviaRadical SRN1 Chemistry

    Article • Nucleosides and Nucleotides, June 1994, Taylor & Francis

    Dr Rachid Benhida

  100. Tetrasubstituted N-Azolyl Olefins via Products from Sequential S RN 1 Reactions

    Article • Synlett, January 1994, Thieme Publishing Group

    Dr Rachid Benhida

  101. N-1 Oxidation of Adenine Substituted at N-9 by an Olefinic Chain

    Article • Heterocycles, January 1994, Japan Institute of Heterocyclic Chemistry

    Dr Rachid Benhida

  102. SYNTHESES DE CYCLOHEXENONES α-SUBSTITUEES VIA LA THERMOLYSE DE CETOSULFOXYDES TERTIAIRES

    Article • Phosphorus Sulfur and Silicon and the Related Elements, May 1993, Taylor & Francis

    Dr Rachid Benhida