All Stories

  1. Reinterpreting anomalous competitive binding experiments within G protein-coupled receptor homodimers using a dimer receptor model

    Article • Pharmacological Research, January 2019, Elsevier

    Sergi Ferre

  2. Role of placebo effects in pain and neuropsychiatric disorders

    Article • Progress in Neuro-Psychopharmacology and Biological Psychiatry, December 2018, Elsevier

    Sergi Ferre

  3. Revisiting the Functional Role of Dopamine D4 Receptor Gene Polymorphisms: Heteromerization-Dependent Gain of Function of the D4.7 Receptor Variant

    Article • Molecular Neurobiology, November 2018, Springer Science + Business Media

    Sergi Ferre

  4. Design of a True Bivalent Ligand with Picomolar Binding Affinity for a G Protein-Coupled Receptor Homodimer

    Article • Journal of Medicinal Chemistry, September 2018, American Chemical Society (ACS)

    Sergi Ferre

  5. Behavioral and cellular dopamine D1 and D3 receptor-mediated synergy: Implications for L-DOPA-induced dyskinesia

    Article • Neuropharmacology, August 2018, Elsevier

    Sergi Ferre

  6. Fronto-striatal effective connectivity of working memory in adults with cannabis use disorder

    Article • Psychiatry Research Neuroimaging, August 2018, Elsevier

    Sergi Ferre

  7. Key role of adenosine in Restless Legs Syndrome

    Article • The Neuroscientist, July 2018, SAGE Publications

    Sergi Ferre

  8. Adenosine A1-Dopamine D1 Receptor Heteromers Control the Excitability of the Spinal Motoneuron

    Article • Molecular Neurobiology, May 2018, Springer Science + Business Media

    Sergi Ferre

  9. Connectome and molecular pharmacological differences in the dopaminergic system in restless legs syndrome (RLS): plastic changes and neuroadaptations that may contribute to augmentation

    Article • Sleep Medicine, March 2017, Elsevier

    Sergi Ferre

  10. In search of alternatives to dopaminergic ligands for the treatment of restless legs syndrome: iron, glutamate, and adenosine

    Article • Sleep Medicine, March 2017, Elsevier

    Sergi Ferre

  11. Targeting the equilibrative nucleoside transporter ENT1 in Huntington disease

    Article • Oncotarget, February 2017, Impact Journals, LLC

    Sergi Ferre

  12. Allosterism Within GPCR Oligomers: Back to Symmetry

    Article • January 2017, Springer Science + Business Media

    Sergi Ferre

  13. Functional μ-Opioid-Galanin Receptor Heteromers in the Ventral Tegmental Area

    Article • Journal of Neuroscience, December 2016, Society for Neuroscience

    Sergi Ferre

  14. Adenosine receptors as markers of brain iron deficiency: Implications for Restless Legs Syndrome

    Article • Neuropharmacology, December 2016, Elsevier

    Sergi Ferre

  15. Equilibrative nucleoside transporter ENT1 as a biomarker of Huntington disease

    Article • Neurobiology of Disease, December 2016, Elsevier

    Sergi Ferre

  16. Allosteric mechanisms within the adenosine A2A–dopamine D2 receptor heterotetramer

    Article • Neuropharmacology, May 2016, Elsevier

    Sergi Ferre

  17. A Significant Role of the Truncated Ghrelin Receptor GHS-R1b in Ghrelin-induced Signaling in Neurons

    Article • Journal of Biological Chemistry, April 2016, American Society for Biochemistry & Molecular Biology (ASBMB)

    Sergi Ferre

  18. Evidence for the heterotetrameric structure of the adenosine A 2A –dopamine D 2 receptor complex

    Article • Biochemical Society Transactions, April 2016, Portland Press Ltd.

    Sergi Ferre

  19. A Novel Class of Dopamine D4Receptor Ligands Bearing an Imidazoline Nucleus

    Article • ChemMedChem, March 2016, Wiley

    Sergi Ferre

  20. Evidence for Noncanonical Neurotransmitter Activation: Norepinephrine as a Dopamine D2-Like Receptor Agonist

    Article • Molecular Pharmacology, February 2016, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Sergi Ferre

  21. Dissecting striatal adenosine-cannabinoid receptor interactions. New clues from rats over-expressing adenosine A2A receptors

    Article • Journal of Neurochemistry, January 2016, Wiley

    Sergi Ferre

  22. Local Control of Extracellular Dopamine Levels in the Medial Nucleus Accumbens by a Glutamatergic Projection from the Infralimbic Cortex

    Article • Journal of Neuroscience, January 2016, Society for Neuroscience

    Sergi Ferre

  23. Mechanisms of the psychostimulant effects of caffeine: implications for substance use disorders

    Article • Psychopharmacology, January 2016, Springer Science + Business Media

    Sergi Ferre

  24. Cortico-striatal circuits: Novel therapeutic targets for substance use disorders

    Article • Brain Research, December 2015, Elsevier

    Sergi Ferre

  25. Allosteric interactions between agonists and antagonists within the adenosine A 2A receptor-dopamine D 2 receptor heterotetramer

    Article • Proceedings of the National Academy of Sciences, June 2015, Proceedings of the National Academy of Sciences

    Sergi Ferre

  26. Orexin-Corticotropin-Releasing Factor Receptor Heteromers in the Ventral Tegmental Area as Targets for Cocaine

    Article • Journal of Neuroscience, April 2015, Society for Neuroscience

    Sergi Ferre

  27. Caffeine increases striatal dopamine D2/D3 receptor availability in the human brain

    Article • Translational Psychiatry, April 2015, Springer Science + Business Media

    Sergi Ferre

  28. The GPCR heterotetramer: challenging classical pharmacology

    Article • Trends in Pharmacological Sciences, March 2015, Elsevier

    Sergi Ferre

  29. Allosteric Mechanisms in the Adenosine A2A-Dopamine D2 Receptor Heteromer

    Article • January 2015, Springer Science + Business Media

    Sergi Ferre

  30. Synthesis and Biological Evaluation of a Novel Series of Heterobivalent Muscarinic Ligands Based on Xanomeline and 1-[3-(4-Butylpiperidin-1-yl)propyl]-1,2,3,4-tetrahydroquinolin-2-one (77-LH-28-1)

    Article • Journal of Medicinal Chemistry, November 2014, American Chemical Society (ACS)

    Sergi Ferre

  31. Intracellular Calcium Levels Determine Differential Modulation of Allosteric Interactions within G Protein-Coupled Receptor Heteromers

    Article • Chemistry & Biology, November 2014, Elsevier

    Sergi Ferre

  32. Functional Selectivity of Allosteric Interactions within G Protein–Coupled Receptor Oligomers: The Dopamine D1-D3 Receptor Heterotetramer

    Article • Molecular Pharmacology, August 2014, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Sergi Ferre

  33. Differential Effects of Presynaptic versus Postsynaptic Adenosine A2A Receptor Blockade on  9-Tetrahydrocannabinol (THC) Self-Administration in Squirrel Monkeys

    Article • Journal of Neuroscience, May 2014, Society for Neuroscience

    Sergi Ferre

  34. Personality traits and vulnerability or resilience to substance use disorders

    Article • Trends in Cognitive Sciences, April 2014, Elsevier

    Sergi Ferre

  35. Cocaine Disrupts Histamine H3 Receptor Modulation of Dopamine D1 Receptor Signaling:  1-D1-H3 Receptor Complexes as Key Targets for Reducing Cocaine's Effects

    Article • Journal of Neuroscience, March 2014, Society for Neuroscience

    Sergi Ferre

  36. G Protein–Coupled Receptor Oligomerization Revisited: Functional and Pharmacological Perspectives

    Article • Pharmacological Reviews, February 2014, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Sergi Ferre

  37. Receptor Heteromerization

    Article • January 2014, Elsevier

    Sergi Ferre

  38. Reducing cannabinoid abuse and preventing relapse by enhancing endogenous brain levels of kynurenic acid

    Article • Nature Neuroscience, October 2013, Springer Science + Business Media

    Marco Pistis, Dr Gianluigi Tanda, Sergi Ferre

  39. Cocaine Inhibits Dopamine D2 Receptor Signaling via Sigma-1-D2 Receptor Heteromers

    Article • PLoS ONE, April 2013, PLOS

    Sergi Ferre

  40. Psychostimulant pharmacological profile of paraxanthine, the main metabolite of caffeine in humans

    Article • Neuropharmacology, April 2013, Elsevier

    Sergi Ferre

  41. Detection of Receptor Heteromers Involving Dopamine Receptors by the Sequential BRET-FRET Technology

    Article • October 2012, Springer Science + Business Media

    Sergi Ferre

  42. Role of Striatal A2A Receptor Subpopulations in Neurological Disorders

    Article • July 2012, Springer Science + Business Media

    Sergi Ferre

  43. Circadian-Related Heteromerization of Adrenergic and Dopamine D4 Receptors Modulates Melatonin Synthesis and Release in the Pineal Gland

    Article • PLoS Biology, June 2012, PLOS

    Sergi Ferre

  44. Evidence That Sleep Deprivation Downregulates Dopamine D2R in Ventral Striatum in the Human Brain

    Article • Journal of Neuroscience, May 2012, Society for Neuroscience

    Sergi Ferre

  45. Combined effects of THC and caffeine on working memory in rats

    Article • British Journal of Pharmacology, March 2012, Wiley

    Sergi Ferre

  46. Increased Orbitofrontal Brain Activation after Administration of a Selective Adenosine A2A Antagonist in Cocaine Dependent Subjects

    Article • Frontiers in Psychiatry, January 2012, Frontiers

    Sergi Ferre

  47. Past, present and future of A2A adenosine receptor antagonists in the therapy of Parkinson's disease

    Article • Pharmacology & Therapeutics, December 2011, Elsevier

    Sergi Ferre

  48. Functional changes in postsynaptic adenosine A2A receptors during early stages of a rat model of Huntington disease

    Article • Experimental Neurology, November 2011, Elsevier

    Sergi Ferre

  49. Pharmacological evidence for different populations of postsynaptic adenosine A2A receptors in the rat striatum

    Article • Neuropharmacology, October 2011, Elsevier

    Sergi Ferre

  50. Dopamine D4 receptor, but not the ADHD-associated D4.7 variant, forms functional heteromers with the dopamine D2S receptor in the brain

    Article • Molecular Psychiatry, August 2011, Springer Science + Business Media

    Dr. Benjamín Floran, Sergi Ferre

  51. Dopamine-Galanin Receptor Heteromers Modulate Cholinergic Neurotransmission in the Rat Ventral Hippocampus

    Article • Journal of Neuroscience, May 2011, Society for Neuroscience

    Sergi Ferre

  52. Striatal Pre- and Postsynaptic Profile of Adenosine A2A Receptor Antagonists

    Article • PLoS ONE, January 2011, PLOS

    Sergi Ferre

  53. Adenosine A2A Receptors and A2A Receptor Heteromers as Key Players in Striatal Function

    Article • Frontiers in Neuroanatomy, January 2011, Frontiers

    Sergi Ferre

  54. Dopamine D1-histamine H3Receptor Heteromers Provide a Selective Link to MAPK Signaling in GABAergic Neurons of the Direct Striatal Pathway

    Article • Journal of Biological Chemistry, December 2010, American Society for Biochemistry & Molecular Biology (ASBMB)

    Sergi Ferre

  55. Reinforcing and neurochemical effects of cannabinoid CB1 receptor agonists, but not cocaine, are altered by an adenosine A2A receptor antagonist

    Article • Addiction Biology, November 2010, Wiley

    Sergi Ferre

  56. Direct involvement of σ-1 receptors in the dopamine D 1 receptor-mediated effects of cocaine

    Article • Proceedings of the National Academy of Sciences, October 2010, Proceedings of the National Academy of Sciences

    Sergi Ferre, Professor Kjell Fuxe

  57. Up-regulation of striatal adenosine A2A receptors with iron deficiency in rats

    Article • Experimental Neurology, July 2010, Elsevier

    Sergi Ferre

  58. Interactions between Intracellular Domains as Key Determinants of the Quaternary Structure and Function of Receptor Heteromers

    Article • Journal of Biological Chemistry, June 2010, American Society for Biochemistry & Molecular Biology (ASBMB)

    Sergi Ferre

  59. Role of the Central Ascending Neurotransmitter Systems in the Psychostimulant Effects of Caffeine

    Article • Journal of Alzheimer s Disease, April 2010, IOS Press

    Sergi Ferre

  60. Platforms for the identification of GPCR targets, and of orthosteric and allosteric modulators

    Article • Expert Opinion on Drug Discovery, March 2010, Informa Healthcare

    Sergi Ferre

  61. Adenosine-cannabinoid receptor interactions. Implications for striatal function

    Article • British Journal of Pharmacology, March 2010, Wiley

    Sergi Ferre

  62. Calcium-mediated modulation of the quaternary structure and function of adenosine A2A–dopamine D2 receptor heteromers

    Article • Current Opinion in Pharmacology, February 2010, Elsevier

    Sergi Ferre

  63. Oligomerization of G-protein-coupled receptors: A reality

    Article • Current Opinion in Pharmacology, February 2010, Elsevier

    Sergi Ferre

  64. GPCR homomers and heteromers: A better choice as targets for drug development than GPCR monomers?

    Article • Pharmacology & Therapeutics, November 2009, Elsevier

    Sergi Ferre

  65. Interactions between Calmodulin, Adenosine A2A, and Dopamine D2Receptors

    Article • Journal of Biological Chemistry, July 2009, American Society for Biochemistry & Molecular Biology (ASBMB)

    Sergi Ferre, Professor Kjell Fuxe

  66. Metabotropic glutamate type 5, dopamine D2and adenosine A2areceptors form higher-order oligomers in living cells

    Article • Journal of Neurochemistry, June 2009, Wiley

    Sergi Ferre

  67. Marked changes in signal transduction upon heteromerization of dopamine D1 and histamine H3 receptors

    Article • British Journal of Pharmacology, April 2009, Wiley

    Sergi Ferre

  68. Building a new conceptual framework for receptor heteromers

    Article • Nature Chemical Biology, March 2009, Springer Science + Business Media

    Sergi Ferre, Professor Kjell Fuxe

  69. GDNF control of the glutamatergic cortico-striatal pathway requires tonic activation of adenosine A2Areceptors

    Article • Journal of Neurochemistry, March 2009, Wiley

    Sergi Ferre

  70. Diminished iron concentrations increase adenosine A2A receptor levels in mouse striatum and cultured human neuroblastoma cells

    Article • Experimental Neurology, February 2009, Elsevier

    Sergi Ferre

  71. G-protein-coupled receptor heteromers: function and ligand pharmacology

    Article • British Journal of Pharmacology, January 2009, Wiley

    Sergi Ferre

  72. Key Modulatory Role of Presynaptic Adenosine A2AReceptors in Cortical Neurotransmission to the Striatal Direct Pathway

    Article • The Scientific World JOURNAL, January 2009, Hindawi Publishing Corporation

    Sergi Ferre

  73. Looking for the role of cannabinoid receptor heteromers in striatal function

    Article • Neuropharmacology, January 2009, Elsevier

    Sergi Ferre

  74. Plasma membrane diffusion of g protein-coupled receptor oligomers

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, December 2008, Elsevier

    Sergi Ferre

  75. La cafeína en la enfermedad de Parkinson

    Article • Medicina Clínica, November 2008, Elsevier

    Sergi Ferre

  76. Dopamine D2 and Adenosine A2A Receptors Regulate NMDA-Mediated Excitation in Accumbens Neurons Through A2A–D2 Receptor Heteromerization

    Article • Neuropsychopharmacology, September 2008, Springer Science + Business Media

    Sergi Ferre

  77. Sleep Deprivation Decreases Binding of [11C]Raclopride to Dopamine D2/D3 Receptors in the Human Brain

    Article • Journal of Neuroscience, August 2008, Society for Neuroscience

    Sergi Ferre

  78. Effects of chronic caffeine exposure on adenosinergic modulation of the discriminative-stimulus effects of nicotine, methamphetamine, and cocaine in rats

    Article • Psychopharmacology, August 2008, Springer Science + Business Media

    Sergi Ferre

  79. How Calmodulin Interacts with the Adenosine A2Aand the Dopamine D2Receptors

    Article • Journal of Proteome Research, August 2008, American Chemical Society (ACS)

    Sergi Ferre, Professor Kjell Fuxe

  80. Interactions between histamine H3 and dopamine D2 receptors and the implications for striatal function

    Article • Neuropharmacology, August 2008, Elsevier

    Sergi Ferre

  81. Novel pharmacological targets based on receptor heteromers

    Article • Brain Research Reviews, August 2008, Elsevier

    Sergi Ferre

  82. Identification of Dopamine D1–D3Receptor Heteromers

    Article • Journal of Biological Chemistry, July 2008, American Society for Biochemistry & Molecular Biology (ASBMB)

    Sergi Ferre, Professor Kjell Fuxe

  83. Detection of heteromerization of more than two proteins by sequential BRET-FRET

    Article • Nature Methods, June 2008, Springer Science + Business Media

    Sergi Ferre, Professor Kjell Fuxe

  84. An Update on Adenosine A2A-Dopamine D2 Receptor Interactions: Implications for the Function of G Protein-Coupled Receptors

    Article • Current Pharmaceutical Design, May 2008, Bentham Science Publishers

    Sergi Ferre

  85. Potential Therapeutic Interest of Adenosine A2A Receptors in Psychiatric Disorders

    Article • Current Pharmaceutical Design, May 2008, Bentham Science Publishers

    Sergi Ferre

  86. An update on the mechanisms of the psychostimulant effects of caffeine

    Article • Journal of Neurochemistry, May 2008, Wiley

    Sergi Ferre

  87. Adenosine A1-A2A receptor heteromers: new targets for caffeine in the brain

    Article • Frontiers in Bioscience, January 2008, Frontiers in Bioscience

    Sergi Ferre

  88. Light resonance energy transfer-based methods in the study of G protein-coupled receptor oligomerization

    Article • BioEssays, January 2008, Wiley

    Sergi Ferre

  89. Adenosine A2A receptors and basal ganglia physiology

    Article • Progress in Neurobiology, December 2007, Elsevier

    Sergi Ferre

  90. Adenosine A2A receptors in ventral striatum, hypothalamus and nociceptive circuitry

    Article • Progress in Neurobiology, December 2007, Elsevier

    Sergi Ferre

  91. Old and new ways to calculate the affinity of agonists and antagonists interacting with G-protein-coupled monomeric and dimeric receptors: The receptor–dimer cooperativity index

    Article • Pharmacology & Therapeutics, December 2007, Elsevier

    Sergi Ferre

  92. Adenosine receptor–dopamine receptor interactions in the basal ganglia and their relevance for brain function

    Article • Physiology & Behavior, September 2007, Elsevier

    Sergi Ferre, Professor Kjell Fuxe

  93. Functional relevance of neurotransmitter receptor heteromers in the central nervous system

    Article • Trends in Neurosciences, September 2007, Elsevier

    Sergi Ferre

  94. Neurotransmitter receptor heteromers and their integrative role in ‘local modules’: The striatal spine module

    Article • Brain Research Reviews, August 2007, Elsevier

    Sergi Ferre, Professor Kjell Fuxe

  95. 5-HT1B Receptor-Mediated Serotoninergic Modulation of Methylphenidate-Induced Locomotor Activation in Rats

    Article • Neuropsychopharmacology, May 2007, Springer Science + Business Media

    Sergi Ferre

  96. Differential glutamate-dependent and glutamate-independent adenosine A1receptor-mediated modulation of dopamine release in different striatal compartments

    Article • Journal of Neurochemistry, April 2007, Wiley

    Sergi Ferre

  97. Striatal Adenosine A2A and Cannabinoid CB1 Receptors Form Functional Heteromeric Complexes that Mediate the Motor Effects of Cannabinoids

    Article • Neuropsychopharmacology, March 2007, Springer Science + Business Media

    Sergi Ferre

  98. Adenosine Receptor Heteromers and their Integrative Role in Striatal Function

    Article • The Scientific World JOURNAL, January 2007, Hindawi Publishing Corporation

    Sergi Ferre, Professor Kjell Fuxe

  99. Basic Concepts in G-Protein-Coupled Receptor Homo- and Heterodimerization

    Article • The Scientific World JOURNAL, January 2007, Hindawi Publishing Corporation

    Sergi Ferre

  100. Heteromerization of G-Protein–Coupled Receptors. Implications for Central Nervous System Function and Dysfunction

    Article • The Scientific World JOURNAL, January 2007, Hindawi Publishing Corporation

    Sergi Ferre

  101. Sponsor's Foreword

    Article • The Scientific World JOURNAL, January 2007, Hindawi Publishing Corporation

    Sergi Ferre

  102. Working memory deficits in transgenic rats overexpressing human adenosine A2A receptors in the brain

    Article • Neurobiology of Learning and Memory, January 2007, Elsevier

    Sergi Ferre, Professor Kjell Fuxe

  103. Allosteric Modulation of Dopamine D2Receptors by Homocysteine

    Article • Journal of Proteome Research, November 2006, American Chemical Society (ACS)

    Sergi Ferre, Professor Kjell Fuxe

  104. Intramembrane receptor–receptor interactions: a novel principle in molecular medicine

    Article • Journal of Neural Transmission, October 2006, Springer Science + Business Media

    Sergi Ferre, Professor Kjell Fuxe

  105. Heterodimeric adenosine receptors: a device to regulate neurotransmitter release

    Article • Cellular and Molecular Life Sciences, October 2006, Springer Science + Business Media

    Sergi Ferre

  106. Blockade of Adenosine A2A Receptors Prevents Protein Phosphorylation in the Striatum Induced by Cortical Stimulation

    Article • Journal of Neuroscience, October 2006, Society for Neuroscience

    Sergi Ferre

  107. Receptor–receptor interactions involving adenosine A1 or dopamine D1 receptors and accessory proteins

    Article • Journal of Neural Transmission, October 2006, Springer Science + Business Media

    Sergi Ferre, Professor Kjell Fuxe

  108. Dopamine D2 Receptor-Mediated Regulation of Serotonin Extracellular Concentration in the Dorsal Raphe Nucleus of Freely Moving Rats

    Article • Journal of Neurochemistry, October 2006, Wiley

    Sergi Ferre

  109. Heteromeric Nicotinic Acetylcholine–Dopamine Autoreceptor Complexes Modulate Striatal Dopamine Release

    Article • Neuropsychopharmacology, May 2006, Springer Science + Business Media

    Sergi Ferre

  110. The Two-State Dimer Receptor Model: A General Model for Receptor Dimers

    Article • Molecular Pharmacology, February 2006, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Sergi Ferre, Professor Kjell Fuxe

  111. Presynaptic Control of Striatal Glutamatergic Neurotransmission by Adenosine A1-A2A Receptor Heteromers

    Article • Journal of Neuroscience, February 2006, Society for Neuroscience

    Sergi Ferre

  112. Stimulation of Adenosine Receptors Selectively Activates Gene Expression in Striatal Enkephalinergic Neurons

    Article • Neuropsychopharmacology, February 2006, Springer Science + Business Media

    Sergi Ferre

  113. ROLE OF ADENOSINE IN THE CONTROL OF HOMOSYNAPTIC PLASTICITY IN STRIATAL EXCITATORY SYNAPSES

    Article • Journal of Integrative Neuroscience, December 2005, World Scientific Pub Co Pte Lt

    Sergi Ferre

  114. A detailed behavioral analysis of the acute motor effects of caffeine in the rat: involvement of adenosine A1 and A2A receptors

    Article • Psychopharmacology, October 2005, Springer Science + Business Media

    Sergi Ferre

  115. Amazing Stability of the Arginine−Phosphate Electrostatic Interaction

    Article • Journal of Proteome Research, August 2005, American Chemical Society (ACS)

    Sergi Ferre

  116. Dimer-based model for heptaspanning membrane receptors

    Article • Trends in Biochemical Sciences, July 2005, Elsevier

    Sergi Ferre, Professor Kjell Fuxe

  117. Nanomolar concentrations of kynurenic acid reduce extracellular dopamine levels in the striatum

    Article • Journal of Neurochemistry, May 2005, Wiley

    Sergi Ferre

  118. How receptor mosaics decode transmitter signals. Possible relevance of cooperativity

    Article • Trends in Biochemical Sciences, April 2005, Elsevier

    Sergi Ferre, Professor Kjell Fuxe

  119. Role of central and peripheral adenosine receptors in the cardiovascular responses to intraperitoneal injections of adenosine A1and A2Asubtype receptor agonists

    Article • British Journal of Pharmacology, March 2005, Wiley

    Sergi Ferre

  120. Involvement of adenosine A1 receptors in the discriminative-stimulus effects of caffeine in rats

    Article • Psychopharmacology, February 2005, Springer Science + Business Media

    Sergi Ferre

  121. Adenosine A2A and Dopamine D2 Heteromeric Receptor Complexes and Their Function

    Article • Journal of Molecular Neuroscience, January 2005, Springer Science + Business Media

    Sergi Ferre, Professor Kjell Fuxe

  122. Computer-Assisted Image Analysis of Caveolin-1 Involvement in the Internalization Process of Adenosine A2A–Dopamine D2 Receptor Heterodimers

    Article • Journal of Molecular Neuroscience, January 2005, Springer Science + Business Media

    Sergi Ferre, Professor Kjell Fuxe

  123. Heptaspanning Membrane Receptors and Cytoskeletal/Scaffolding Proteins: Focus on Adenosine, Dopamine, and Metabotropic Glutamate Receptor Function

    Article • Journal of Molecular Neuroscience, January 2005, Springer Science + Business Media

    Sergi Ferre

  124. How Proteins Come Together in the Plasma Membrane and Function in Macromolecular Assemblies: Focus on Receptor Mosaics

    Article • Journal of Molecular Neuroscience, January 2005, Springer Science + Business Media

    Sergi Ferre, Professor Kjell Fuxe

  125. Molecular mechanisms involved in the adenosine A1 and A2A receptor-induced neuronal differentiation in neuroblastoma cells and striatal primary cultures

    Article • Journal of Neurochemistry, January 2005, Wiley

    Sergi Ferre, Professor Kjell Fuxe

  126. Partners for Adenosine A1 Receptors

    Article • Journal of Molecular Neuroscience, January 2005, Springer Science + Business Media

    Sergi Ferre, Professor Kjell Fuxe

  127. Receptor–Receptor Interactions, Receptor Mosaics, and Basic Principles of Molecular Network Organization: Possible Implications for Drug Development

    Article • Journal of Molecular Neuroscience, January 2005, Springer Science + Business Media

    Sergi Ferre, Professor Kjell Fuxe

  128. Role of Electrostatic Interaction in Receptor–Receptor Heteromerization

    Article • Journal of Molecular Neuroscience, January 2005, Springer Science + Business Media

    Sergi Ferre, Professor Kjell Fuxe

  129. Adenosine receptor-mediated modulation of dopamine release in the nucleus accumbens depends on glutamate neurotransmission and N-methyl-d-aspartate receptor stimulation

    Article • Journal of Neurochemistry, November 2004, Wiley

    Sergi Ferre

  130. Combining Mass Spectrometry and Pull-Down Techniques for the Study of Receptor Heteromerization. Direct Epitope−Epitope Electrostatic Interactions between Adenosine A2Aand Dopamine D2Receptors

    Article • Analytical Chemistry, September 2004, American Chemical Society (ACS)

    Sergi Ferre, Professor Kjell Fuxe

  131. Neuroprotective effect of L-DOPA co-administered with the adenosine A2A receptor agonist CGS 21680 in an animal model of Parkinson’s disease

    Article • Brain Research Bulletin, August 2004, Elsevier

    Sergi Ferre, Professor Kjell Fuxe

  132. On the Molecular Basis of the Receptor Mosaic Hypothesis of the Engram

    Article • Cellular and Molecular Neurobiology, August 2004, Springer Science + Business Media

    Sergi Ferre, Professor Kjell Fuxe

  133. Energy gradients for the homeostatic control of brain ECF composition and for VT signal migration: introduction of the tide hypothesis

    Article • Journal of Neural Transmission, July 2004, Springer Science + Business Media

    Sergi Ferre, Professor Kjell Fuxe

  134. Adenosine A2A-dopamine D2 receptor–receptor heteromers. Targets for neuro-psychiatric disorders

    Article • Parkinsonism & Related Disorders, July 2004, Elsevier

    Sergi Ferre, Professor Kjell Fuxe

  135. Striatal plasticity at the network level. Focus on adenosine A2A and D2 interactions in models of Parkinson's Disease

    Article • Parkinsonism & Related Disorders, July 2004, Elsevier

    Sergi Ferre, Professor Kjell Fuxe

  136. Studies on homocysteine plasma levels in Alzheimer?s patients. Relevance for neurodegeneration

    Article • Journal of Neural Transmission, May 2004, Springer Science + Business Media

    Sergi Ferre, Professor Kjell Fuxe

  137. Opposite modulatory roles for adenosine A1 and A2A receptors on glutamate and dopamine release in the shell of the nucleus accumbens. Effects of chronic caffeine exposure

    Article • Journal of Neurochemistry, January 2004, Wiley

    Sergi Ferre

  138. Lack of adenosine A1 and dopamine D2 receptor-mediated modulation of the cardiovascular effects of the adenosine A2A receptor agonist CGS 21680

    Article • European Journal of Pharmacology, January 2004, Elsevier

    Sergi Ferre

  139. Homodimerization of adenosine A2A receptors: qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer

    Article • Journal of Neurochemistry, December 2003, Wiley

    Sergi Ferre, Professor Kjell Fuxe

  140. Involvement of Adenosine A1 and A2A Receptors in the Adenosinergic Modulation of the Discriminative-Stimulus Effects of Cocaine and Methamphetamine in Rats

    Article • Journal of Pharmacology and Experimental Therapeutics, October 2003, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Sergi Ferre

  141. Adenosine A2A-Dopamine D2Receptor-Receptor Heteromerization

    Article • Journal of Biological Chemistry, August 2003, American Society for Biochemistry & Molecular Biology (ASBMB)

    Sergi Ferre, Professor Kjell Fuxe

  142. Molecular Mechanisms and Therapeutical Implications of Intramembrane Receptor/Receptor Interactions among Heptahelical Receptors with Examples from the Striatopallidal GABA Neurons

    Article • Pharmacological Reviews, July 2003, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Sergi Ferre, Professor Kjell Fuxe

  143. Regulation of heptaspanning-membrane-receptor function by dimerization and clustering

    Article • Trends in Biochemical Sciences, May 2003, Elsevier

    Sergi Ferre, Professor Kjell Fuxe

  144. Involvement of Adenosine A1 and A2A Receptors in the Motor Effects of Caffeine after its Acute and Chronic Administration

    Article • Neuropsychopharmacology, January 2003, Springer Science + Business Media

    Sergi Ferre, Professor Kjell Fuxe

  145. Interactions among adenosine deaminase, adenosine A1 receptors and dopamine D1 receptors in stably cotransfected fibroblast cells and neurons

    Article • Neuroscience, September 2002, Elsevier

    Sergi Ferre, Professor Kjell Fuxe

  146. Synergistic interaction between adenosine A2A and glutamate mGlu5 receptors: Implications for striatal neuronal function

    Article • Proceedings of the National Academy of Sciences, August 2002, Proceedings of the National Academy of Sciences

    Sergi Ferre, Professor Kjell Fuxe

  147. Adenosinergic modulation of the discriminative-stimulus effects of methamphetamine in rats

    Article • Psychopharmacology, June 2002, Springer Science + Business Media

    Sergi Ferre

  148. Local Dopaminergic Modulation of the Motor Activity Induced by N-methyl-D-aspartate Receptor Stimulation in the Ventral Hippocampus

    Article • Neuropsychopharmacology, June 2002, Springer Science + Business Media

    Sergi Ferre

  149. Metabotropic glutamate mGlu5 receptor-mediated modulation of the ventral striopallidal GABA pathway in rats. Interactions with adenosine A2A and dopamine D2 receptors

    Article • Neuroscience Letters, May 2002, Elsevier

    Sergi Ferre, Professor Kjell Fuxe

  150. Coaggregation, Cointernalization, and Codesensitization of Adenosine A2AReceptors and Dopamine D2Receptors

    Article • Journal of Biological Chemistry, February 2002, American Society for Biochemistry & Molecular Biology (ASBMB)

    Sergi Ferre, Professor Kjell Fuxe

  151. Activation of Adensine A1 and A2A Receptors Modulates Dopamine D2 Receptor-Induced Responses in Stably Transfected Human Neuroblastoma Cells

    Article • Journal of Neurochemistry, December 2001, Wiley

    Sergi Ferre, Professor Kjell Fuxe

  152. The Selective mGlu5 Receptor Agonist CHPG Inhibits Quinpirole-Induced Turning in 6-Hydroxydopamine-Lesioned Rats and Modulates the Binding Characteristics of Dopamine D2 Receptors in the Rat Striatum Interactions with Adenosine A2a Receptors

    Article • Neuropsychopharmacology, October 2001, Springer Science + Business Media

    Sergi Ferre, Professor Kjell Fuxe

  153. Adenosine/dopamine interaction: implications for the treatment of Parkinson's disease

    Article • Parkinsonism & Related Disorders, July 2001, Elsevier

    Sergi Ferre, Professor Kjell Fuxe

  154. Adenosine/dopamine receptor-receptor interactions in the central nervous system

    Article • Drug Development Research, January 2001, Wiley

    Sergi Ferre, Professor Kjell Fuxe

  155. Electrophysiological and behavioural evidence for an antagonistic modulatory role of adenosine A2Areceptors in dopamine D2receptor regulation in the rat dopamine-denervated striatum

    Article • European Journal of Neuroscience, November 2000, Wiley

    Sergi Ferre, Professor Kjell Fuxe

  156. Evidence for Adenosine/Dopamine Receptor Interactions Indications for Heteromerization

    Article • Neuropsychopharmacology, October 2000, Elsevier

    Sergi Ferre, Professor Kjell Fuxe

  157. Dopamine D 1 and adenosine A 1 receptors form functionally interacting heteromeric complexes

    Article • Proceedings of the National Academy of Sciences, July 2000, Proceedings of the National Academy of Sciences

    Sergi Ferre, Professor Kjell Fuxe

  158. Modulation of [35S]GTPγS binding to Chinese hamster ovary cell membranes by D2(short) dopamine receptors

    Article • Neuroscience Letters, February 2000, Elsevier

    Sergi Ferre, Professor Kjell Fuxe

  159. Adenosine as a volume transmission signal. A feedback detector of neuronal activation

    Article • January 2000, Elsevier

    Sergi Ferre, Professor Kjell Fuxe

  160. Effect of N-methyl-d-aspartate on motor activity and in vivo adenosine striatal outflow in the rat

    Article • European Journal of Pharmacology, November 1999, Elsevier

    Sergi Ferre

  161. Stimulation of adenosine A1receptors attenuates dopamine D1receptor-mediated increase of NGFI-A, c-fos and jun-B mRNA levels in the dopamine-denervated striatum and dopamine D1receptor-mediated turning behaviour

    Article • European Journal of Neuroscience, November 1999, Wiley

    Sergi Ferre, Professor Kjell Fuxe

  162. Reciprocal interactions between adenosine A2A and dopamine D2 receptors in Chinese hamster ovary cells co-transfected with the two receptors

    Article • Biochemical Pharmacology, September 1999, Elsevier

    Sergi Ferre, Professor Kjell Fuxe

  163. Adenosine and dopamine receptor antagonist binding in the rat ventral and dorsal striatum: lack of changes after a neonatal bilateral lesion of the ventral hippocampus

    Article • Neurochemistry International, March 1999, Elsevier

    Sergi Ferre, Professor Kjell Fuxe

  164. Adenosine A2A and group I metabotropic glutamate receptors synergistically modulate the binding characteristics of dopamine D2 receptors in the rat striatum

    Article • Neuropharmacology, January 1999, Elsevier

    Sergi Ferre, Professor Kjell Fuxe

  165. Adenosine A1 and A2A receptor antagonists stimulate motor activity: evidence for an increased effectiveness in aged rats

    Article • Neuroscience Letters, July 1998, Elsevier

    Sergi Ferre, Professor Kjell Fuxe

  166. Age-related alteration of the adenosine/dopamine balance in the rat striatum

    Article • Brain Research, June 1998, Elsevier

    Sergi Ferre, Professor Kjell Fuxe

  167. Integrated events in central dopamine transmission as analyzed at multiple levels. Evidence for intramembrane adenosine A2A/dopamine D2 and adenosine A1/dopamine D1 receptor interactions in the basal ganglia1Published on the World Wide Web on 12 Januar...

    Article • Brain Research Reviews, May 1998, Elsevier

    Sergi Ferre, Professor Kjell Fuxe

  168. Differential effects of selective adenosine A1 and A2A receptor agonists on dopamine receptor agonist-induced behavioural responses in rats

    Article • European Journal of Pharmacology, April 1998, Elsevier

    Sergi Ferre, Professor Kjell Fuxe

  169. Adenosine A1Receptor-mediated Modulation of Dopamine D1Receptors in Stably Cotransfected Fibroblast Cells

    Article • Journal of Biological Chemistry, February 1998, American Society for Biochemistry & Molecular Biology (ASBMB)

    Sergi Ferre, Professor Kjell Fuxe

  170. Adenosine–dopamine receptor–receptor interactions as an integrative mechanism in the basal ganglia

    Article • Trends in Neurosciences, October 1997, Elsevier

    Sergi Ferre, Professor Kjell Fuxe

  171. Adenosine-dopamine interactions in the ventral striatum

    Article • Psychopharmacology, September 1997, Springer Science + Business Media

    Sergi Ferre

  172. Adenosine A2A Agonists: A Potential New Type of Atypical Antipsychotic

    Article • Neuropsychopharmacology, August 1997, Springer Science + Business Media

    Sergi Ferre, Professor Kjell Fuxe

  173. Prolonged treatment with haloperidol and clozapine in the rat: differential effects on spontaneous and theophylline-induced motor activity

    Article • Neuroscience Letters, August 1997, Elsevier

    Sergi Ferre, Professor Kjell Fuxe

  174. Different Effects of Dopamine Antagonists on Spontaneous and NMDA-Induced Motor Activity in Mice

    Article • Pharmacology Biochemistry and Behavior, March 1997, Elsevier

    Sergi Ferre

  175. Article • Neurochemical Research, January 1997, Springer Science + Business Media

    Sergi Ferre, Professor Kjell Fuxe

  176. Adenosine A2A receptors modulate the binding characteristics of dopamine D2 receptors in stably cotransfected fibroblast cells

    Article • European Journal of Pharmacology, December 1996, Elsevier

    Sergi Ferre, Professor Kjell Fuxe

  177. Motor depressant effects of systemically administered polyamines in mice: involvement of central NMDA receptors

    Article • European Journal of Pharmacology, December 1996, Elsevier

    Sergi Ferre

  178. Adenosine A1 receptor blockade selectively potentiates the motor effects induced by dopamine D1 receptor stimulation in rodents

    Article • Neuroscience Letters, November 1996, Elsevier

    Sergi Ferre, Professor Kjell Fuxe

  179. Reserpine potentiates NMDA-induced c-fos mRNA expression in the mouse brain

    Article • Neuroscience Letters, July 1996, Elsevier

    Sergi Ferre

  180. Stimulation of adenosine A1 receptors prevents the EEG arousal due to dopamine D1 receptor activation in rabbits

    Article • European Journal of Pharmacology, June 1996, Elsevier

    Sergi Ferre, Professor Kjell Fuxe

  181. Adenosine A1 receptor-dopamine D1 receptor interaction in the rat limbic system: modulation of dopamine D1 receptor antagonist binding sites

    Article • Neuroscience Letters, April 1996, Elsevier

    Sergi Ferre, Professor Kjell Fuxe

  182. A brief appraisal on some aspects of the receptor-receptor interaction

    Article • Neurochemistry International, August 1995, Elsevier

    Sergi Ferre, Professor Kjell Fuxe

  183. Effects of the systemic administration of kainic acid and NMDA on exploratory activity in rats

    Article • Pharmacology Biochemistry and Behavior, June 1995, Elsevier

    Sergi Ferre

  184. Dopamine-independent and adenosine-dependent mechanisms involved in the effects of N-methyl-d-aspartate on motor activity in mice

    Article • European Journal of Pharmacology, March 1995, Elsevier

    Sergi Ferre

  185. Clozapine decreases serotonin extracellular levels in the nucleus accumbens by a dopamine receptor-independent mechanism

    Article • Neuroscience Letters, February 1995, Elsevier

    Sergi Ferre

  186. Antagonistic interaction between adenosine A2A receptors and dopamine D2 receptors in the ventral striopallidal system. Implications for the treatment of schizophrenia

    Article • Neuroscience, December 1994, Elsevier

    Sergi Ferre, Professor Kjell Fuxe

  187. Unilateral neonatal intracerebroventricular 6-hydroxydopamine administration in rats: II. Effects on extracellular monoamine, acetylcholine and adenosine levels monitored with in vivo microdialysis

    Article • Psychopharmacology, December 1994, Springer Science + Business Media

    Sergi Ferre

  188. Chronic haloperidol treatment leads to an increase in the intramembrane interaction between adenosine A2 and dopamine D2 receptors in the neostriatum

    Article • Psychopharmacology, November 1994, Springer Science + Business Media

    Sergi Ferre, Professor Kjell Fuxe

  189. PEC-60 increases dopamine but not GABA release in the dorsolateral neostriatum of the halothane anaesthetized rat. An in vivo microdialysis study

    Article • Neuroscience Letters, August 1994, Elsevier

    Sergi Ferre, Professor Kjell Fuxe

  190. Motor activation in short- and long-term reserpinized mice: role of , dopamine D1 and dopamine D2 receptors

    Article • European Journal of Pharmacology, April 1994, Elsevier

    Sergi Ferre

  191. Receptor-receptor interactions as an integrative mechanism in nerve cells

    Article • Molecular Neurobiology, September 1993, Springer Science + Business Media

    Sergi Ferre, Professor Kjell Fuxe

  192. Antagonistic A2a/D2receptor interactions in the striatum as a basis for adenosine/dopamine interactions in the central nervous system

    Article • Drug Development Research, March 1993, Wiley

    Sergi Ferre

  193. Noradrenergic modulation of midbrain dopamine cell firing elicited by stimulation of the locus coeruleus in the rat

    Article • Journal of Neural Transmission, February 1993, Springer Science + Business Media

    Sergi Ferre

  194. Opposing actions of an adenosine A2 receptor agonist and a GTP analogue on the regulation of dopamine D2 receptors in rat neostriatal membranes

    Article • European Journal of Pharmacology Molecular Pharmacology, February 1993, Elsevier

    Sergi Ferre, Professor Kjell Fuxe

  195. Adenosine-dopamine interactions in the brain

    Article • Neuroscience, December 1992, Elsevier

    Sergi Ferre, Professor Kjell Fuxe

  196. Dopamine denervation leads to an increase in the intramembrane interaction between adenosine A2 and dopamine D2 receptors in the neostriatum

    Article • Brain Research, October 1992, Elsevier

    Sergi Ferre, Professor Kjell Fuxe

  197. Neuropeptides, excitatory amino acid and adenosine A2 receptors regulate D2 receptors via intramembrane receptor-receptor interactions. Relevance for Parkinson's disease and schizophrenia

    Article • Neurochemistry International, March 1992, Elsevier

    Sergi Ferre, Professor Kjell Fuxe

  198. High-performance liquid chromatographic separation of caffeine, theophylline, theobromine and paraxanthine in rat brain and serum

    Article • Journal of Chromatography B Biomedical Sciences and Applications, September 1991, Elsevier

    Sergi Ferre

  199. Stimulation of adenosine A2 receptors induces catalepsy

    Article • Neuroscience Letters, September 1991, Elsevier

    Sergi Ferre, Professor Kjell Fuxe

  200. A trypsin inhibitor-like peptide PEC-60 reduces the affinity of dopamine D2 agonist binding sites in rat neostriatal membranes

    Article • European Journal of Pharmacology Molecular Pharmacology, August 1991, Elsevier

    Sergi Ferre, Professor Kjell Fuxe

  201. Postsynaptic dopamine/adenosine interaction: I. Adenosine analogues inhibit dopamine D2-mediated behaviour in short-term reserpinized mice

    Article • European Journal of Pharmacology, January 1991, Elsevier

    Sergi Ferre

  202. Postsynaptic dopamine/adenosine interaction: II. Postsynaptic dopamine agonism and adenosine antagonism of methylxanthines in short-term reserpinized mice

    Article • European Journal of Pharmacology, January 1991, Elsevier

    Sergi Ferre

  203. Paraxanthine displaces the binding of [3H]SCH 23390 from rat striatal membranes

    Article • European Journal of Pharmacology, April 1990, Elsevier

    Dr Joan Sallés, Sergi Ferre

  204. Is experimental catalepsy properly measured?

    Article • Pharmacology Biochemistry and Behavior, April 1990, Elsevier

    Sergi Ferre

  205. Effect of unilateral nucleus basalis lesion on cortical and striatal acetylcholine and dopamine release monitored in vivo with microdialysis

    Article • Neuroscience Letters, March 1990, Elsevier

    Sergi Ferre

  206. T-maze performance in rats following chronic neuroleptic treatment

    Article • Pharmacology Biochemistry and Behavior, February 1990, Elsevier

    Sergi Ferre

  207. BHT-920 and LY-171555 (quinpirole) have similar affinities for striatal D-2 dopamine receptors, and similar affinities for striatal D-1 dopamine receptors

    Article • European Journal of Pharmacology, July 1989, Elsevier

    Dr Joan Sallés, Sergi Ferre

  208. Rotational behaviour induced by theophylline in 6-OHDA nigrostriatal denervated rats is dependent on the supersensitivity of striatal dopaminergic receptors

    Article • Pharmacology Biochemistry and Behavior, July 1989, Elsevier

    Sergi Ferre

  209. Relationship between rotational behaviour induced by apomorphine and caffeine in rats with unilateral lesion of the nigrostriatal pathway

    Article • Neuropharmacology, April 1989, Elsevier

    Sergi Ferre

  210. Methylxanthines cause a decrease of prolactin plasma levels in healthy non-pregnant women

    Article • Human Psychopharmacology Clinical and Experimental, March 1989, Wiley

    Sergi Ferre

  211. Conditioning of rotational behavior after the administration of a single dose of apomorphine in rats with unilateral denervation of the dopaminergic nigrostriatal pathway: Relevance to drug addiction

    Article • Pharmacology Biochemistry and Behavior, November 1988, Elsevier

    Sergi Ferre

  212. Theophylline reverses haloperidol-induced catalepsy in the rat possible relevance to the pharmacological treatment of psychosis

    Article • Biological Psychiatry, October 1988, Elsevier

    Sergi Ferre

  213. Comparison between apomorphine and amphetamine-induced rotational behaviour in rats with a unilateral nigrostriatal pathway lesion

    Article • Neuropharmacology, June 1988, Elsevier

    Sergi Ferre

  214. L-dopa causes an acute, partial and reversible reversal of denervation-induced supersensitivity of striatal dopaminergic receptors

    Article • Psychopharmacology, February 1987, Springer Science + Business Media

    Sergi Ferre