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  1. Transfection of the BDNF Gene in the Surviving Dopamine Neurons in Conjunction with Continuous Administration of Pramipexole Restores Normal Motor Behavior in a Bilateral Rat Model of Parkinson’s Disease

    Article • Parkinson s Disease, February 2024, Hindawi Publishing Corporation

    Dr. Benjamín Floran

  2. Modulation of D3R Splicing, Signaling, and Expression by D1R through PKA→PTB Phosphorylation

    Article • Biomedicines, January 2024, MDPI AG

    Dr. Benjamín Floran

  3. Dopamine D3 receptor modulates D2 receptor effects on cAMP and GABA release at striatopallidal terminals—Modulation by the Ca2+–Calmodulin–CaMKII system

    Article • European Journal of Neuroscience, December 2023, Wiley

    Dr. Benjamín Floran

  4. PEG 400:Trehalose Coating Enhances Curcumin-Loaded PLGA Nanoparticle Internalization in Neuronal Cells

    Article • Pharmaceutics, May 2023, MDPI AG

    Dr. Benjamín Floran

  5. Pharmacological targeting of G protein-coupled receptor heteromers

    Article • Pharmacological Research, November 2022, Elsevier

    Dr. Benjamín Floran

  6. Repositioning of drugs for Parkinson’s disease and pharmaceutical nanotechnology tools for their optimization

    Article • Journal of Nanobiotechnology, September 2022, Springer Science + Business Media

    Dr. Benjamín Floran, Dr Javad Sharifi Rad

  7. Hypothalamic A11 Nuclei Regulate the Circadian Rhythm of Spinal Mechanonociception through Dopamine Receptors and Clock Gene Expression

    Article • Life, September 2022, MDPI AG

    Dr. Benjamín Floran

  8. Presynaptic nigral GPR55 receptors stimulate [ 3 H]‐GABA release through [ 3 H]‐cAMP production and PKA activation and promote motor behavior

    Article • Synapse, July 2022, Wiley

    Dr. Benjamín Floran

  9. Optoception: Perception of Optogenetic Brain Perturbations

    Article • eNeuro, May 2022, Society for Neuroscience

    Dr. Benjamín Floran

  10. Association of α-1-Antichymotrypsin Expression with the Development of Conformational Changes of Tau Protein in Alzheimer’s Disease Brain

    Article • Neuroscience, January 2022, Elsevier

    Dr. Benjamín Floran, Dr Francisco Garcia Garcia-Sierra

  11. Day-Night Variations in the Concentration of Neurotransmitters in the Rat Lumbar Spinal Cord

    Article • Journal of Circadian Rhythms, July 2021, Ubiquity Press, Ltd.

    Dr. Benjamín Floran

  12. Current progress of self-healing polymers for medical applications in tissue engineering

    Article • Iranian Polymer Journal, May 2021, Springer Science + Business Media

    Dr. Benjamín Floran, Dr Javad Sharifi Rad

  13. Optoception: perception of optogenetic brain stimulation

    Article • April 2021, Cold Spring Harbor Laboratory Press

    Dr. Benjamín Floran

  14. Molecular Processing of Tau Protein in Progressive Supranuclear Palsy: Neuronal and Glial Degeneration

    Article • Journal of Alzheimer s Disease, February 2021, IOS Press

    Dr. Benjamín Floran

  15. Curcumin for parkinson´s disease: potential therapeutic effects, molecular mechanisms, and nanoformulations to enhance its efficacy

    Article • Cellular and Molecular Biology, January 2021, CMB Association

    Dr. Benjamín Floran, Dr Javad Sharifi Rad

  16. CB1/5-HT/GABA interactions and food intake regulation

    Article • January 2021, Elsevier

    Dr. Benjamín Floran

  17. Dopamine D4 receptor modulates inhibitory transmission in pallido‐pallidal terminals and regulates motor behavior

    Article • European Journal of Neuroscience, November 2020, Wiley

    Dr Hernán Cortés, Dr. Benjamín Floran

  18. Activation of STAT3 Regulates Reactive Astrogliosis and Neuronal Death Induced by AβO Neurotoxicity

    Article • International Journal of Molecular Sciences, October 2020, MDPI AG

    Dr. Benjamín Floran, Dr. Genaro Patino-Lopez

  19. Chitosan-decorated nanoparticles for drug delivery

    Article • Journal of Drug Delivery Science and Technology, October 2020, Elsevier

    Dr Hernán Cortés, Dr. Benjamín Floran, Dr Javad Sharifi Rad

  20. Early but not late conformational changes of tau in association with ubiquitination of neurofibrillary pathology in Alzheimer’s disease brains

    Article • Brain Research, October 2020, Elsevier

    Dr. Benjamín Floran

  21. Hypothalamic A11 Nuclei Regulate the Circadian Rhythm of the Mechanonociception and the Spinal Clock Gene Transcription through Dopamine Receptor Activation

    Article • September 2020, MDPI AG

    Dr. Benjamín Floran

  22. The treatment of Goji berry (Lycium barbarum) improves the neuroplasticity of the prefrontal cortex and hippocampus in aged rats

    Article • The Journal of Nutritional Biochemistry, September 2020, Elsevier

    Dr. Benjamín Floran, Dr GONZALO FLORES

  23. γ-Aminobutyric acid (GABA) from satellite glial cells tonically depresses the excitability of primary afferent fibers

    Article • Neuroscience Research, September 2020, Elsevier

    Dr. Benjamín Floran

  24. A Reevaluation of Chitosan-Decorated Nanoparticles to Cross the Blood-Brain Barrier

    Article • Membranes, August 2020, MDPI AG

    Dr. Benjamín Floran, Dr Hernán Cortés

  25. RECENT ADVANCES IN ELASTIN-BASED BIOMATERIALS

    Article • Journal of Pharmacy & Pharmaceutical Sciences, August 2020, University of Alberta Libraries

    Dr. Benjamín Floran, Dr Hernán Cortés

  26. Xanthan gum in drug release

    Article • Cellular and Molecular Biology, June 2020, CMB Association

    Dr Hernán Cortés, Dr. Benjamín Floran

  27. Hyaluronic acid in wound dressings

    Article • Cellular and Molecular Biology, June 2020, CMB Association

    Dr Hernán Cortés, Dr. Benjamín Floran

  28. Coexistence of D 3 R typical and atypical signaling in striatonigral neurons during dopaminergic denervation. Correlation with D 3 nf expression changes

    Article • Synapse, February 2020, Wiley

    Dr. Benjamín Floran, Dr Hernán Cortés

  29. Differential calcium channel‐mediated dopaminergic modulation in the subthalamonigral synapse

    Article • Synapse, February 2020, Wiley

    Dr. Benjamín Floran

  30. Cannabinoids CB2 Receptors, One New Promising Drug Target for Chronic and Degenerative Pain Conditions in Equine Veterinary Patients

    Article • Journal of Equine Veterinary Science, February 2020, Elsevier

    Dr. Benjamín Floran

  31. Cdk5 phosphorylates CaV1.3 channels and regulates GABAA-mediated miniature inhibitory post-synaptic currents in striato-nigral terminals

    Article • Biochemical and Biophysical Research Communications, January 2020, Elsevier

    Dr. Benjamín Floran

  32. D 2 autoreceptor switches CB 2 receptor effects on [ 3 H]‐dopamine release in the striatum

    Article • Synapse, October 2019, Wiley

    Dr Hernán Cortés, Dr. Benjamín Floran

  33. Blockade of Intranigral and Systemic D3 Receptors Stimulates Motor Activity in the Rat Promoting a Reciprocal Interaction Among Glutamate, Dopamine, and GABA

    Article • Biomolecules, September 2019, MDPI AG

    Dr Hernán Cortés, Dr. Benjamín Floran

  34. Phospho-Tau Protein Expression in the Cell Cycle of SH-SY5Y Neuroblastoma Cells: A Morphological Study

    Article • Journal of Alzheimer s Disease, September 2019, IOS Press

    Dr. Benjamín Floran, José Luna, Professor George Perry

  35. Severity of Dyskinesia and D3R Signaling Changes Induced by L-DOPA Treatment of Hemiparkinsonian Rats Are Features Inherent to the Treated Subjects

    Article • Biomolecules, September 2019, MDPI AG

    Dr Hernán Cortés, Dr. Benjamín Floran

  36. Development and Evaluation of Alginate Membranes with Curcumin-Loaded Nanoparticles for Potential Wound-Healing Applications

    Article • Pharmaceutics, August 2019, MDPI AG

    Dr Hernán Cortés, Dr. Benjamín Floran

  37. Presynaptic Control of [3H]-Glutamate Release by Dopamine Receptor Subtypes in the Rat Substantia Nigra. Central Role of D1 and D3 Receptors

    Article • Neuroscience, March 2019, Elsevier

    Dr Hernán Cortés, Dr. Benjamín Floran

  38. Formulations of Curcumin Nanoparticles for Brain Diseases

    Article • Biomolecules, February 2019, MDPI AG

    Dr Hernán Cortés, Dr. Benjamín Floran

  39. CB1 receptors in the paraventricular nucleus of the hypothalamus modulate the release of 5-HT and GABA to stimulate food intake in rats

    Article • European Neuropsychopharmacology, November 2018, Elsevier

    Dr. Benjamín Floran

  40. Presynaptic cannabinoid CB2 receptors modulate [3 H]-Glutamate release at subthalamo-nigral terminals of the rat

    Article • Synapse, August 2018, Wiley

    Dr Hernán Cortés, Dr. Benjamín Floran

  41. The neuropeptide-12 improves recognition memory and neuronal plasticity of the limbic system in old rats

    Article • Synapse, June 2018, Wiley

    Dr fidel lopez De la Cruz, Dr. Benjamín Floran, Dr GONZALO FLORES

  42. Presynaptic Dopamine D2 Receptors Modulate [ 3 H]GABA Release at StriatoPallidal Terminals via Activation of PLC → IP3 → Calcineurin and Inhibition of AC → cAMP → PKA Signaling Cascades

    Article • Neuroscience, December 2017, Elsevier

    Dr Hernán Cortés, Dr. Benjamín Floran

  43. Nanotechnology As Potential Tool for siRNA Delivery in Parkinson's Disease

    Article • Current Drug Targets, November 2017, Bentham Science Publishers

    Professor David Quintanar-Guerrero, Dr Hernán Cortés, Dr. Benjamín Floran

  44. Curcuma treatment prevents cognitive deficit and alteration of neuronal morphology in the limbic system of aging rats

    Article • Synapse, January 2017, Wiley

    Dr. Benjamín Floran, Dr GONZALO FLORES

  45. Cannabinoid-induced depression of synaptic transmission is switched to stimulation when dopaminergic tone is increased in the globus pallidus of the rodent

    Article • Neuropharmacology, November 2016, Elsevier

    Dr Hernán Cortés, Dr. Benjamín Floran

  46. Fibrillar Amyloid-β Accumulation Triggers an Inflammatory Mechanism Leading to Hyperphosphorylation of the Carboxyl-Terminal End of Tau Polypeptide in the Hippocampal Formation of the 3×Tg-AD Transgenic Mouse

    Article • Journal of Alzheimer s Disease, April 2016, IOS Press

    Dr. Juan Pedro Luna-Arias, Professor George Perry, José Luna, Dr. Benjamín Floran, Juan Pedro Luna-Arias

  47. Chronic administration of resveratrol prevents morphological changes in prefrontal cortex and hippocampus of aged rats

    Article • Synapse, February 2016, Wiley

    Dr GONZALO FLORES, Dr. Benjamín Floran

  48. Nanoparticle technology for treatment of Parkinson's disease: the role of surface phenomena in reaching the brain

    Article • Drug Discovery Today, July 2015, Elsevier

    Dr Hernán Cortés, Dr. Benjamín Floran

  49. Neuroinflammation and Alteration of the Blood-Brain Barrier in Alzheimer´s Disease

    Article • July 2015, IntechOpen

    Dr. Benjamín Floran

  50. The relationship between truncation and phosphorylation at the C-terminus of tau protein in the paired helical filaments of Alzheimer's disease

    Article • Frontiers in Neuroscience, February 2015, Frontiers

    Juan Pedro Luna-Arias, Dr. Benjamín Floran

  51. Dopaminergic denervation switches dopamine D3 receptor signaling and disrupts its Ca2+ dependent modulation by CaMKII and calmodulin in striatonigral projections of the rat

    Article • Neurobiology of Disease, February 2015, Elsevier

    Dr Hernán Cortés, Dr. Benjamín Floran

  52. Dopamine Receptors and Neurodegeneration

    Article • Aging and Disease, January 2015, Aging and Disease

    Dr. Benjamín Floran

  53. Cannabinoid CB1 receptors activation and coactivation with D2 receptors modulate GABAergic neurotransmission in the globus pallidus and increase motor asymmetry

    Article • Synapse, December 2014, Wiley

    Dr. Benjamín Floran

  54. Stimulation of dopamine D4 receptors in the paraventricular nucleus of the hypothalamus of male rats induces hyperphagia: Involvement of glutamate

    Article • Physiology & Behavior, June 2014, Elsevier

    Dr. Benjamín Floran

  55. Accumulation of Abnormally Processed Tau Protein in Neuronal Cells as a Biomarker for Dementia

    Article • April 2014, IntechOpen

    Dr. Benjamín Floran

  56. Pathophysiology of L-Dopa Induced Dyskinesia — Changes in D1/D3 Receptors and Their Signaling Pathway

    Article • March 2014, IntechOpen

    Dr. Benjamín Floran

  57. L-type Ca2+ channel activity determines modulation of GABA release by dopamine in the substantia nigra reticulata and the globus pallidus of the rat

    Article • Neuroscience, January 2014, Elsevier

    Dr. Benjamín Floran

  58. Presynaptic CaMKIIα modulates dopamine D3 receptor activation in striatonigral terminals of the rat brain in a Ca2+ dependent manner

    Article • Neuropharmacology, August 2013, Elsevier

    Dr Hernán Cortés, Dr. Benjamín Floran

  59. D3 dopamine receptors interact with dopamine D1 but not D4 receptors in the GABAergic terminals of the SNr of the rat

    Article • Neuropharmacology, April 2013, Elsevier

    Dr. Benjamín Floran

  60. Phosphorylation of Tau Protein Associated as a Protective Mechanism in the Presence of Toxic, C-Terminally Truncated Tau in Alzheimer's Disease

    Article • February 2013, IntechOpen

    Dr. Benjamín Floran

  61. Changes on D2-like receptor induced Gi protein activation and hippocampal dopamine release in kindled rats

    Article • Progress in Neuro-Psychopharmacology and Biological Psychiatry, January 2013, Elsevier

    Dr. Benjamín Floran

  62. Endogenous Content and Release of [3H]-GABA and [3H]-Glutamate in the Spinal Cord of Chronically Undernourished Rat

    Article • Neurochemical Research, September 2012, Springer Science + Business Media

    Dr. Benjamín Floran

  63. Dopamine D4 receptor stimulation in GABAergic projections of the globus pallidus to the reticular thalamic nucleus and the substantia nigra reticulata of the rat decreases locomotor activity

    Article • Neuropharmacology, February 2012, Elsevier

    Dr. Benjamín Floran

  64. Dopamine D4 receptor, but not the ADHD-associated D4.7 variant, forms functional heteromers with the dopamine D2S receptor in the brain

    Article • Molecular Psychiatry, August 2011, Springer Science + Business Media

    Dr. Benjamín Floran, Sergi Ferre

  65. l-DOPA-induced dyskinesia in hemiparkinsonian rats is associated with up-regulation of adenylyl cyclase type V/VI and increased GABA release in the substantia nigra reticulata

    Article • Neurobiology of Disease, January 2011, Elsevier

    Dr. Benjamín Floran

  66. GABAB receptors modulate depolarization-stimulated [3H]glutamate release in slices of the pars reticulata of the rat substantia nigra

    Article • European Journal of Pharmacology, December 2010, Elsevier

    Dr Hernán Cortés, Dr. Benjamín Floran

  67. Dopamine inhibits GABA transmission from the globus pallidus to the thalamic reticular nucleus via presynaptic D4 receptors

    Article • Neuroscience, September 2010, Elsevier

    Dr. Benjamín Floran

  68. Los Receptores Dopaminérgicos D2/D3 hipotalámicos particpan en la regulación del comportamiento alimentario

    Article • Revista Mexicana de Análisis de la Conducta, July 2010, Sociedad Mexicana de Analisis de la Conducta

    Dr. Benjamín Floran

  69. D4 and D1 dopamine receptors modulate [3H]GABA release in the substantia nigra pars reticulata of the rat

    Article • Neuropharmacology, December 2009, Elsevier

    Dr. Benjamín Floran

  70. Role of cannabinoid CB1 receptors on macronutrient selection and satiety in rats

    Article • Physiology & Behavior, March 2009, Elsevier

    Dr. Benjamín Floran

  71. Cannabinoid Agonists Stimulate [3H]GABA Release in the Globus Pallidus of the Rat When Gi Protein-Receptor Coupling Is Restricted: Role of Dopamine D2 Receptors

    Article • Journal of Pharmacology and Experimental Therapeutics, December 2008, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr. Benjamín Floran

  72. 6-OHDA-induced hemiparkinsonism and chronic l-DOPA treatment increase dopamine D1-stimulated [3H]-GABA release and [3H]-cAMP production in substantia nigra pars reticulata of the rat

    Article • Neuropharmacology, October 2008, Elsevier

    Dr. Benjamín Floran

  73. Presynaptic D1 dopamine receptors facilitate glutamatergic neurotransmission in the rat globus pallidus

    Article • Neuroscience Letters, October 2007, Elsevier

    Dr. Benjamín Floran

  74. GABAB receptor activation inhibits dopamine D1 receptor-mediated facilitation of [3H]GABA release in substantia nigra pars reticulata

    Article • Neuropharmacology, October 2007, Elsevier

    Dr. Benjamín Floran

  75. Dopamine D1 receptor facilitation of depolarization-induced release of γ-amino-butyric acid in rat striatum is mediated by the cAMP/PKA pathway and involves P/Q-type calcium channels

    Article • Synapse, January 2007, Wiley

    Dr. Benjamín Floran

  76. Adenosine A2A receptor stimulation decreases GAT-1-mediated GABA uptake in the globus pallidus of the rat

    Article • Neuropharmacology, July 2006, Elsevier

    Dr. Benjamín Floran

  77. L-DOPA inhibits depolarization-induced [3H]GABA release in the dopamine-denervated globus pallidus of the rat: the effect is dopamine independent and mediated by D2-like receptors

    Article • Journal of Neural Transmission, June 2006, Springer Science + Business Media

    Dr Hernán Cortés, Dr. Benjamín Floran

  78. Control of the Subthalamic Innervation of Substantia Nigra Pars Reticulata by D1 and D2 Dopamine Receptors

    Article • Journal of Neurophysiology, March 2006, American Physiological Society

    Dr. Benjamín Floran

  79. Activación de receptores dopaminérgicos por L-DOPA. De la acción terapéutica a las discinesias.

    Article • REVISTA BIOMÉDICA, October 2005, Center for Regional Research Hideyo Noguchi

    Dr. Benjamín Floran

  80. Interactions between adenosine A2a and dopamine D2 receptors in the control of [3H]GABA release in the globus pallidus of the rat

    Article • European Journal of Pharmacology, September 2005, Elsevier

    Dr. Benjamín Floran

  81. Dopamine D4 receptors inhibit depolarization-induced [3H]GABA release in the rat subthalamic nucleus

    Article • European Journal of Pharmacology, September 2004, Elsevier

    Dr. Benjamín Floran

  82. Activation of dopamine D4 receptors modulates [3H]GABA release in slices of the rat thalamic reticular nucleus

    Article • Neuropharmacology, March 2004, Elsevier

    Dr. Benjamín Floran

  83. Adenosine A1 receptors control dopamine D1-dependent [3H]GABA release in slices of substantia nigra pars reticulata and motor behavior in the rat

    Article • Neuroscience, December 2002, Elsevier

    Dr. Benjamín Floran

  84. Intrapallidal dopamine restores motor deficits induced by 6-hydroxydopamine in the rat

    Article • Journal of Neural Transmission, June 2001, Springer Science + Business Media

    Dr. Benjamín Floran

  85. Histamine H3receptor-mediated inhibition of depolarization-induced, dopamine D1receptor-dependent release of [3H]-γ-aminobutyric acid from rat striatal slices

    Article • British Journal of Pharmacology, May 2001, Wiley

    Dr. Benjamín Floran

  86. Regulated release of serotonin from axonal growth cones isolated from the fetal rat brain

    Article • Neurochemistry International, January 1998, Elsevier

    Dr. Benjamín Floran

  87. D2 receptor-mediated inhibition of GABA release by endogenous dopamine in the rat globus pallidus

    Article • Neuroscience Letters, November 1997, Elsevier

    Dr. Benjamín Floran

  88. Reciprocal interaction between glutamate and dopamine in the pars reticulata of the rat substantia nigra: a microdialysis study

    Article • Neuroscience, July 1997, Elsevier

    Dr GONZALO FLORES, Dr. Benjamín Floran

  89. Histamine H3 receptor activation selectively inhibits dopamine D1 receptor-dependent [3H]GABA release from depolarization-stimulated slices of rat substantia nigra pars reticulata

    Article • Neuroscience, June 1997, Elsevier

    Dr. Benjamín Floran

  90. D-1 receptor mediated modulation of the release of γ-aminobutyric acid by endogenous dopamine in the basal ganglia of the rat

    Article • Progress in Neuro-Psychopharmacology and Biological Psychiatry, September 1995, Elsevier

    Dr. Benjamín Floran

  91. D1 Receptor Mediated Trophic Action of Dopamine on the Synthesis of GABA at the Terminals of Striatal Projections

    Article • January 1994, Springer Science + Business Media

    Dr. Benjamín Floran

  92. Activation of D1 receptors stimulates accumulation of γ-aminobutyric acid in slices of the pars reticulata of 6-hydroxydopamine-lesioned rats

    Article • Neuroscience Letters, September 1992, Elsevier

    Dr GONZALO FLORES, Dr. Benjamín Floran

  93. l-DOPA stimulates the release of [3H]γ-aminobutyric acid in the basal ganglia of 6-hydroxydopamine lesioned rats

    Article • Neuroscience Letters, January 1991, Elsevier

    Dr. Benjamín Floran

  94. Activation of D1 dopamine receptors stimulates the release of GABA in the basal ganglia of the rat

    Article • Neuroscience Letters, August 1990, Elsevier

    Dr. Benjamín Floran

  95. Presynaptic modulation of the release of GABA by GABAA receptors in pars compacta and by GABAB receptors in pars reticulata of the rat substantia nigra

    Article • European Journal of Pharmacology, June 1988, Elsevier

    Dr. Benjamín Floran