All Stories

  1. Emerging Roles of Purinergic Signaling in Diabetes

    Article • Medicinal Chemistry, July 2018, Bentham Science Publishers

    Professor Diego Dal Ben, Professor Elena Adinolfi

  2. Exploring the 7-oxo-thiazolo[5,4-d]pyrimidine core for the design of new human adenosine A3 receptor antagonists. Synthesis, molecular modeling studies and pharmacological evaluation

    Article • European Journal of Medicinal Chemistry, May 2015, Elsevier

    Professor Diego Dal Ben

  3. Editorial (Thematic Issue: Purinergic P2X Receptors: Physiological and Pathological Roles and Potential as Therapeutic Targets)

    Article • Current Medicinal Chemistry, February 2015, Bentham Science Publishers

    Professor Diego Dal Ben, Professor Elena Adinolfi

  4. Purinergic P2X receptors: Structural models and analysis of ligand-target interaction

    Article • European Journal of Medicinal Chemistry, January 2015, Elsevier

    Professor Diego Dal Ben

  5. 1,2,4-Triazolo[1,5-a]quinoxaline derivatives and their simplified analogues as adenosine A3 receptor antagonists. Synthesis, structure–affinity relationships and molecular modeling studies

    Article • Bioorganic & Medicinal Chemistry, January 2015, Elsevier

    Professor Diego Dal Ben

  6. Pharmacological postconditioning of the rabbit heart with non-selective, A1, A2Aand A3adenosine receptor agonists

    Article • Journal of Pharmacy and Pharmacology, April 2014, Wiley

    Dr Ioanna Andreadou, Professor Diego Dal Ben

  7. Antiproliferative Evaluation of Isofuranodiene on Breast and Prostate Cancer Cell Lines

    Article • The Scientific World JOURNAL, January 2014, Hindawi Publishing Corporation

    Professor Diego Dal Ben

  8. Different efficacy of adenosine and NECA derivatives at the human A3 adenosine receptor: Insight into the receptor activation switch

    Article • Biochemical Pharmacology, January 2014, Elsevier

    Professor Diego Dal Ben

  9. 8-(2-Furyl)adenine derivatives as A2A adenosine receptor ligands

    Article • European Journal of Medicinal Chemistry, December 2013, Elsevier

    Professor Diego Dal Ben

  10. Evaluation of adenine as scaffold for the development of novel P2X3 receptor antagonists

    Article • European Journal of Medicinal Chemistry, July 2013, Elsevier

    Professor Diego Dal Ben

  11. Pyrazolo[1,5-c]quinazoline derivatives and their simplified analogues as adenosine receptor antagonists: Synthesis, structure–affinity relationships and molecular modeling studies

    Article • Bioorganic & Medicinal Chemistry, January 2013, Elsevier

    Professor Diego Dal Ben

  12. Simulation and comparative analysis of binding modes of nucleoside and non-nucleoside agonists at the A2B adenosine receptor

    Article • In Silico Pharmacology, January 2013, Springer Science + Business Media

    Professor Diego Dal Ben

  13. ChemInform Abstract: New 9-Methyl-8-(4-hydroxyphenyl)adenine Derivatives as A1Adenosine Receptor Antagonists.

    Article • ChemInform, February 2012, Wiley

    Professor Diego Dal Ben

  14. ChemInform Abstract: Neuropeptide S Receptor: Recent Updates on Nonpeptide Antagonist Discovery

    Article • ChemInform, August 2011, Wiley

    Professor Diego Dal Ben

  15. Innovative functional cAMP assay for studying G protein-coupled receptors: application to the pharmacological characterization of GPR17

    Article • Purinergic Signalling, July 2011, Springer Science + Business Media

    Professor Diego Dal Ben

  16. Comparison and optimization of transient transfection methods at human astrocytoma cell line 1321N1

    Article • Analytical Biochemistry, July 2011, Elsevier

    Professor Diego Dal Ben

  17. Synthesis, structure–affinity relationships, and molecular modeling studies of novel pyrazolo[3,4-c]quinoline derivatives as adenosine receptor antagonists

    Article • Bioorganic & Medicinal Chemistry, June 2011, Elsevier

    Professor Diego Dal Ben

  18. Inside Cover: Evidence for the Existence of a Specific G Protein-Coupled Receptor Activated by Guanosine (ChemMedChem 6/2011)

    Article • ChemMedChem, May 2011, Wiley

    Professor Diego Dal Ben

  19. Evidence for the Existence of a Specific G Protein-Coupled Receptor Activated by Guanosine

    Article • ChemMedChem, April 2011, Wiley

    Professor Diego Dal Ben

  20. The Importance of Alkynyl Chain Presence for the Activity of Adenine Nucleosides/Nucleotides on Purinergic Receptors

    Article • Current Medicinal Chemistry, April 2011, Bentham Science Publishers

    Professor Diego Dal Ben

  21. Neuropeptide S Receptor: Recent Updates on Nonpeptide Antagonist Discovery

    Article • ChemMedChem, March 2011, Wiley

    Professor Diego Dal Ben

  22. New 9-methyl-8-(4-hydroxyphenyl)adenine derivatives as A1 adenosine receptor antagonists

    Article • Collection of Czechoslovak Chemical Communications, January 2011, Institute of Organic Chemistry & Biochemistry

    Professor Diego Dal Ben

  23. Molecular modeling study on potent and selective adenosine A3 receptor agonists

    Article • Bioorganic & Medicinal Chemistry, November 2010, Elsevier

    Professor Diego Dal Ben

  24. Adenosine Receptor Modeling: What Does the A2A Crystal Structure Tell Us?

    Article • Current Topics in Medicinal Chemistry, July 2010, Bentham Science Publishers

    Professor Diego Dal Ben

  25. Molecular Modeling Studies on the Human Neuropeptide S Receptor and Its Antagonists

    Article • ChemMedChem, February 2010, Wiley

    Professor Diego Dal Ben

  26. Synthesis and Biological Evaluation of 2-Alkynyl- N 6 -methyl-5′- N -methylcarboxamidoadenosine Derivatives as Potent and Highly Selective Agonists for the Human Adenosine A 3 Receptor ‡

    Article • Journal of Medicinal Chemistry, December 2009, American Chemical Society (ACS)

    Professor Diego Dal Ben

  27. Adenine-Based Acyclic Nucleotides as Novel P2X 3 Receptor Ligands

    Article • Journal of Medicinal Chemistry, August 2009, American Chemical Society (ACS)

    Professor Diego Dal Ben

  28. Adenosine A2AReceptor Antagonists: New 8-Substituted 9-Ethyladenines as Tools for in vivo Rat Models of Parkinson's Disease

    Article • ChemMedChem, June 2009, Wiley

    Professor Diego Dal Ben

  29. 8-Bromo-9-alkyl adenine derivatives as tools for developing new adenosine A2A and A2B receptors ligands

    Article • Bioorganic & Medicinal Chemistry, April 2009, Elsevier

    Professor Diego Dal Ben

  30. Identification of α1-adrenoceptor subtypes involved in contraction of young CD rat epididymal vas deferens

    Article • European Journal of Pharmacology, January 2009, Elsevier

    Professor Diego Dal Ben

  31. Novel potent and highly selective human A3 adenosine receptor antagonists belonging to the 4-amido-2-arylpyrazolo[3,4-c]quinoline series: Molecular docking analysis and pharmacological studies

    Article • Bioorganic & Medicinal Chemistry, January 2009, Elsevier

    Professor Diego Dal Ben

  32. Design, synthesis, and biological evaluation of new mitonafide derivatives as potential antitumor drugs

    Article • Bioorganic & Medicinal Chemistry, September 2008, Elsevier

    Professor Diego Dal Ben

  33. ChemInform Abstract: Synthesis and Biological Activity of Trisubstituted Adenines as A2AAdenosine Receptor Antagonists

    Article • ChemInform, March 2008, Wiley

    Professor Diego Dal Ben

  34. Synthesis and Antitumor Evaluation of Bis Aza-anthracene-9,10-diones and Bis Aza-anthrapyrazole-6-ones

    Article • Journal of Medicinal Chemistry, February 2008, American Chemical Society (ACS)

    Professor Diego Dal Ben

  35. Amide bond direction modulates G-quadruplex recognition and telomerase inhibition by 2,6 and 2,7 bis-substituted anthracenedione derivatives

    Article • Bioorganic & Medicinal Chemistry, January 2008, Elsevier

    Professor Claudia Sissi, Professor Diego Dal Ben

  36. Synthesis and Stability Studies of 2′,3′,5′-tri-O-Acetyl-2-Amino(-N6-Cyclopentyl)-1-Deazaadenosines

    Article • Nucleosides Nucleotides & Nucleic Acids, November 2007, Taylor & Francis

    Professor Diego Dal Ben

  37. Synthesis and Biological Activity of Trisubstituted Adenines as A2AAdenosine Receptor Antagonists

    Article • Nucleosides Nucleotides & Nucleic Acids, November 2007, Taylor & Francis

    Professor Diego Dal Ben

  38. DNA Topoisomerase II Structures and Anthracycline Activity: Insights into Ternary Complex Formation

    Article • Current Pharmaceutical Design, September 2007, Bentham Science Publishers

    Professor Diego Dal Ben

  39. New 2,6,9-trisubstituted adenines as adenosine receptor antagonists: a preliminary SAR profile

    Article • Purinergic Signalling, September 2007, Springer Science + Business Media

    Professor Diego Dal Ben

  40. Highlights on the Development of A2A Adenosine Receptor Agonists and Antagonists

    Article • ChemInform, June 2007, Wiley

    Professor Diego Dal Ben

  41. Highlights on the Development of A2A Adenosine Receptor Agonists and Antagonists

    Article • ChemMedChem, March 2007, Wiley

    Professor Diego Dal Ben

  42. N 6 -Methoxy-2-alkynyladenosine Derivatives as Highly Potent and Selective Ligands at the Human A 3 Adenosine Receptor

    Article • Journal of Medicinal Chemistry, March 2007, American Chemical Society (ACS)

    Professor Diego Dal Ben

  43. Antiviral Properties of Deazaadenine Nucleoside Derivatives

    Article • Current Medicinal Chemistry, December 2006, Bentham Science Publishers

    Professor Diego Dal Ben

  44. Erratum to: Molecular modelling study of 2-phenylethynyladenosine (PEAdo) derivatives as highly selective A3 adenosine receptor ligands

    Article • Purinergic Signalling, October 2006, Springer Science + Business Media

    Professor Diego Dal Ben

  45. Molecular modelling study of 2-phenylethynyladenosine (PEAdo) derivatives as highly selective A3 adenosine receptor ligands

    Article • Purinergic Signalling, August 2006, Springer Science + Business Media

    Professor Diego Dal Ben

  46. GPCRs as therapeutic targets: a view on adenosine receptors structure and functions, and molecular modeling support

    Article • Journal of the Iranian Chemical Society, September 2005, Springer Science + Business Media

    Professor Diego Dal Ben

  47. Interaction Model for Anthracycline Activity against DNA Topoisomerase II †

    Article • Biochemistry, June 2004, American Chemical Society (ACS)

    Professor Diego Dal Ben

  48. Toward the rational design of protein kinase casein kinase-2 inhibitors

    Article • Pharmacology & Therapeutics, February 2002, Elsevier

    Professor Diego Dal Ben