All Stories

  1. Structural characterization of PaaX, the main repressor of the phenylacetate degradation pathway in Escherichia coli W: A novel fold of transcription regulator proteins
  2. Ethoxylate Polymer-Based 96-Well Screen for Protein Crystallization
  3. Characterization of a novel recombinant calcium-binding protein from Arca subcrenata and its anti-hepatoma activities in vitro and in vivo
  4. Engineering broad-spectrum inhibitors of inflammatory chemokines from subclass A3 tick evasins
  5. Repurposed inhibitor of bacterial dihydrodipicolinate reductase exhibits effective herbicidal activity
  6. Distinct Assemblies of Heterodimeric Cytokine Receptors Govern Stemness Programs in Leukemia
  7. TcpA from the Clostridium perfringens plasmid pCW3 is more closely related to the DNA translocase FtsK than to coupling proteins
  8. Crystal structure of a subtilisin-like autotransporter passenger domain reveals insights into its cytotoxic function
  9. The role of auxiliary domains in modulating CHD4 activity suggests mechanistic commonality between enzyme families
  10. Phenol sensing in nature is modulated via a conformational switch governed by dynamic allostery
  11. Structural and functional characterization of Cas2 of CRISPR-Cas subtype I-C lacking the CRISPR component
  12. Crystal structure of the putative cell-wall lipoglycan biosynthesis protein LmcA from Mycobacterium smegmatis
  13. Structural characterization of the ANTAR antiterminator domain bound to RNA
  14. β-Methyltryptamine Provoking the Crucial Role of Strictosidine Synthase Tyr151-OH for Its Stereoselective Pictet−Spengler Reactions to Tryptoline-type Alkaloids
  15. Structural basis of dimerization and nucleic acid binding of human DBHS proteins NONO and PSPC1
  16. Graphene and Graphene Oxide as a Support for Biomolecules in the Development of Biosensors
  17. Data evaluation on the fly: Auto-Rickshaw on the MX beamlines of the Australian Synchrotron
  18. Uncovering the structures and mechanisms for the largest group of bacterial surface virulence factors
  19. Towards novel herbicide modes of action by inhibiting lysine biosynthesis in plants
  20. Salmonella enterica BcfH Is a Trimeric Thioredoxin-Like Bifunctional Enzyme with Both Thiol Oxidase and Disulfide Isomerase Activities
  21. Helicobacter pylori Xanthine–Guanine–Hypoxanthine Phosphoribosyltransferase—A Putative Target for Drug Discovery against Gastrointestinal Tract Infections
  22. Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism
  23. Differential lysine‐mediated allosteric regulation of plant dihydrodipicolinate synthase isoforms
  24. Crystal structure and site-directed mutagenesis of circular bacteriocin plantacyclin B21AG reveals cationic and aromatic residues important for antimicrobial activity
  25. Crystal structure of posnjakite formed in the first crystal water-cooling line of the ANSTO Melbourne Australian Synchrotron MX1 Double Crystal Monochromator
  26. Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism
  27. The basis for non-canonical ROK family function in the N-acetylmannosamine kinase from the pathogen Staphylococcus aureus
  28. Mis‐annotations of a promising antibiotic target in high‐priority gram‐negative pathogens
  29. Structural basis for differentiation between two classes of thiolase: Degradative vs biosynthetic thiolase
  30. Identification of two dihydrodipicolinate synthase isoforms from Pseudomonas aeruginosa that differ in allosteric regulation
  31. Stereocomplementary Chemoenzymatic Pictet–Spengler Reactions for Formation of Rare Azepino-indole Frameworks: Discovery of Antimalarial Compounds
  32. Combining random microseed matrix screening and the magic triangle for the efficient structure solution of a potential lysin from bacteriophage P68
  33. The Structural Basis for a Transition State That Regulates Pore Formation in a Bacterial Toxin
  34. Unique structural features of a bacterial autotransporter adhesin suggest mechanisms for interaction with host macromolecules
  35. Lanthanoid Heteroleptic Complexes with Cucurbit[5]uril and Dicarboxylate Ligands: From Discrete Structures to One-Dimensional and Two-Dimensional Polymers
  36. Crystal structure of TcpK in complex with oriT DNA of the antibiotic resistance plasmid pCW3
  37. Design of Protein-Based Biosensors for Selective Detection of Benzene Groups of Pollutants
  38. Beetle luciferases with naturally red- and blue-shifted emission
  39. Description of the MX2 research instrument at the Australian Synchrotron (ANSTO)
  40. NEW STRUCTURAL FEATURES REVEAL HOW BACTERIA STICK TO HOST SURFACES
  41. Molecular evolution of an oligomeric biocatalyst functioning in lysine biosynthesis
  42. Crystallographic analysis of β-ketoadipyl-CoA thiolase from Psedomonas putida
  43. Online automated structure solution from multiple data sets
  44. Structure-guided design of aromatic biosensors for water quality monitoring
  45. Structure of SgK223 pseudokinase reveals novel mechanisms of homotypic and heterotypic association
  46. Functional insights into the mode of DNA and ligand binding of the TetR family regulator TylP from Streptomyces fradiae
  47. Structure Guided Design of Protein Biosensors for Phenolic Pollutants
  48. Structure and Function of Cyanobacterial DHDPS and DHDPR
  49. Interdomain Conformational Changes Provide Allosteric Regulation en Route to Chorismate
  50. A critical examination of the recently reported crystal structures of the human SMN protein
  51. Structural basis of selective aromatic pollutant sensing by MopR, an NtrC family transcriptional regulator
  52. Structural Determinants Defining the Allosteric Inhibition of an Essential Antibiotic Target
  53. Structural Basis of Selective Aromatic Pollutant Sensing by the Effector Binding Domain of MopR, an NtrC Family Transcriptional Regulator
  54. Campylobacter jejuni adenosine triphosphate phosphoribosyltransferase is an active hexamer that is allosterically controlled by the twisting of a regulatory tail
  55. A crystallographic study of human NONO (p54nrb): overcoming pathological problems with purification, data collection and noncrystallographic symmetry
  56. Cover Picture: Radiation Damage and Racemic Protein Crystallography Reveal the Unique Structure of the GASA/Snakin Protein Superfamily (Angew. Chem. Int. Ed. 28/2016)
  57. Titelbild: Radiation Damage and Racemic Protein Crystallography Reveal the Unique Structure of the GASA/Snakin Protein Superfamily (Angew. Chem. 28/2016)
  58. Radiation Damage and Racemic Protein Crystallography Reveal the Unique Structure of the GASA/Snakin Protein Superfamily
  59. Radiation Damage and Racemic Protein Crystallography Reveal the Unique Structure of the GASA/Snakin Protein Superfamily
  60. Psychromonas ingrahamii diaminopimelate decarboxylase with LLP
  61. Combining cross-crystal averaging and MRSAD to phase a 4354-amino-acid structure
  62. Stonefish toxin defines an ancient branch of the perforin-like superfamily
  63. Cyclic Peptides Incorporating Phosphotyrosine Mimetics as Potent and Specific Inhibitors of the Grb7 Breast Cancer Target
  64. Automated structure solution from multiple data sets
  65. Functional Coupling of Duplex Translocation to DNA Cleavage in a Type I Restriction Enzyme
  66. A step towards long-wavelength protein crystallography: subjecting protein crystals to a vacuum
  67. MX1: a bending-magnet crystallography beamline serving both chemical and macromolecular crystallography communities at the Australian Synchrotron
  68. Quaternary Structure Analyses of an Essential Oligomeric Enzyme
  69. The Crystal Structure of a Homodimeric Pseudomonas Glyoxalase I Enzyme Reveals Asymmetric Metallation Commensurate with Half‐of‐Sites Activity
  70. Crystal structure of Clostridium acetobutylicum aspartate kinase (CaAk): An important allosteric enzyme for amino acids production
  71. Ligand structures of synthetic deoxa-pyranosylamines with raucaffricine and strictosidine glucosidases provide structural insights into their binding and inhibitory behaviours
  72. Post-translational modification and extended glycosylation pattern of a plant latex peroxidase of native source characterized by X-ray crystallography
  73. Alternative phasing method in macromolecular crystallography
  74. Chemical Crystallography at the Australian Synchrotron MX Beamlines
  75. The structure of an ABC toxin particle determined by X-ray crystallography and single particle EM.
  76. The Three-dimensional Structure of the Extracellular Adhesion Domain of the Sialic Acid-binding Adhesin SabA from Helicobacter pylori
  77. WXG100 Protein Superfamily Consists of Three Subfamilies and Exhibits an α-Helical C-Terminal Conserved Residue Pattern
  78. Importance of Hydrophobic Cavities in Allosteric Regulation of Formylglycinamide Synthetase: Insight from Xenon Trapping and Statistical Coupling Analysis
  79. Importance of Hydrophobic Cavities in Allosteric Regulation of Formylglycinamide Synthetase: Insight from Xenon Trapping and Statistical Coupling Analysis
  80. Importance of Hydrophobic Cavities in Allosteric Regulation of Formylglycinamide Synthetase: Insight from Xenon Trapping and Statistical Coupling Analysis
  81. Cloning to crystallization of dihydrodipicolinate synthase from the intracellular pathogenLegionella pneumophila
  82. Phasing selenomethionine proteins using UV-induced radiation damage
  83. Putative dioxygen-binding sites and recognition of tigecycline and minocycline in the tetracycline-degrading monooxygenase TetX
  84. The BC component of ABC toxins is an RHS-repeat-containing protein encapsulation device
  85. High speed X-ray analysis of plant enzymes at room temperature
  86. Cyanuric acid hydrolase: evolutionary innovation by structural concatenation
  87. High speed X-ray analysis of plant enzymes at room temperature
  88. In-house UV radiation-damage-induced phasing of selenomethionine-labeled protein structures
  89. High-resolution structure ofBombyx morilipoprotein 7: crystallographic determination of the identity of the protein and its potential role in detoxification
  90. Structural insight in histo‐blood group binding by the F18 fimbrial adhesin FedF
  91. Purification, crystallization and preliminary crystallographic analysis of banyan peroxidase
  92. The crystal structure of the CRISPR-associated protein Csn2 from Streptococcus agalactiae
  93. Structural basis for modification of flavonol and naphthol glucoconjugates by Nicotiana tabacum malonyltransferase (NtMaT1)
  94. Formylglycinamide ribonucleotide amidotransferase fromSalmonella typhimurium: role of ATP complexation and the glutaminase domain in catalytic coupling
  95. Nonprocessive [2 + 2]e - off-loading reductase domains from mycobacterial nonribosomal peptide synthetases
  96. Correction to Scaffold Tailoring by a Newly Detected Pictet–Spenglerase Activity of Strictosidine Synthase: From the Common Tryptoline Skeleton to the Rare Piperazino-indole Framework
  97. Crystal Structure of Perakine Reductase, Founding Member of a Novel Aldo-Keto Reductase (AKR) Subfamily That Undergoes Unique Conformational Changes during NADPH Binding
  98. Crystal structure of NAD+-dependent Peptoniphilus asaccharolyticus glutamate dehydrogenase reveals determinants of cofactor specificity
  99. The sensor region of the ubiquitous cytosolic sensor kinase, PdtaS, contains PAS and GAF domain sensing modules
  100. Scaffold Tailoring by a Newly Detected Pictet–Spenglerase Activity of Strictosidine Synthase: From the Common Tryptoline Skeleton to the Rare Piperazino-indole Framework
  101. The impact of structural biology on alkaloid biosynthesis research
  102. Current methods in structural proteomics and its applications in biological sciences
  103. Structures of Alkaloid Biosynthetic Glucosidases Decode Substrate Specificity
  104. Structures of Alkaloid Biosynthetic Glucosidases Decode Substrate Specificity
  105. Structures of Alkaloid Biosynthetic Glucosidases Decode Substrate Specificity
  106. Insights into ubiquitin-conjugating enzyme/ co-activator interactions from the structure of the Pex4p:Pex22p complex
  107. Structures of Alkaloid Biosynthetic Glucosidases Decode Substrate Specificity
  108. Structural Insights into the Mechanism of Protein O-Fucosylation
  109. Phasing selenomethionine proteins using UV induced radiation damage
  110. S-SAD phasing of proteinO-fucosyltransferase-1 at a resolution of 2.6 Å in the monoclinic space groupC2
  111. On the routine use of soft X-rays in macromolecular crystallography. Part V. Molecular replacement and anomalous scattering
  112. Crystallization and preliminary X-ray crystallographic studies of an oligomeric species of a refolded C39 peptidase-like domain of theEscherichia coliABC transporter haemolysin B
  113. Additional phase information from UV damage of selenomethionine labelled proteins
  114. Structural Basis for the Oxidation of Protein-bound Sulfur by the Sulfur Cycle Molybdohemo-Enzyme Sulfane Dehydrogenase SoxCD
  115. Structural Characterization of the Multidomain Regulatory Protein Rv1364c from Mycobacterium tuberculosis
  116. Single isomorphous replacement phasing of selenomethionine-containing proteins using UV-induced radiation damage
  117. Update on the tutorial for learning and teaching macromolecular crystallography
  118. Update on the tutorial for learning and teaching macromolecular crystallography
  119. Expression, purification and X-ray analysis of 1,3-propanediol dehydrogenase (Aq_1145) fromAquifex aeolicusVF5
  120. On the combination of molecular replacement and single-wavelength anomalous diffraction phasing for automated structure determination
  121. Crystal Structure of Polyneuridine Aldehyde Esterase Complexed with 16-epi-Vellosimine
  122. Crystal structure of polyneuridine aldehyde esterase
  123. Structure of the C-terminal domain of nsp4 from Feline Coronavirus
  124. Auto-Rickshaw: a tool for online validation of X-ray diffraction experiment
  125. Structure of the C-terminal domain of NSP4 from feline infection peritonitis virus
  126. Structure of the C-terminal domain of nsp4 from feline coronavirus
  127. Strukturbasis und Enzymmechanismus der Biosynthese von C9‐ aus C10‐monoterpenoiden Indol‐Alkaloiden
  128. Structural Basis and Enzymatic Mechanism of the Biosynthesis of C9‐ from C10‐Monoterpenoid Indole Alkaloids
  129. The F4 fimbrial chaperone FaeE is stable as a monomer that does not require self-capping of its pilin-interactive surfaces
  130. Structural analysis reveals DNA binding properties of Rv2827c, a hypothetical protein from Mycobacterium tuberculosis
  131. The impact of Structural Proteomics on Biotechnology
  132. Structure of the motor subunit of type I restriction-modification complex EcoR124I
  133. A tutorial for learning and teaching macromolecular crystallography
  134. Structural Basis for Parasite-Specific Functions of the Divergent Profilin of Plasmodium falciparum
  135. Purification, crystallization and X-ray diffraction analysis of pavineN-methyltransferase fromThalictrum flavum
  136. C4-Dicarboxylates Sensing Mechanism Revealed by the Crystal Structures of DctB Sensor Domain
  137. A tutorial for learning and teaching macromolecular crystallography
  138. Auto-Rickshaw: an online tool for validation of an X-ray diffraction experiment
  139. High crystallizability under air-exclusion conditions of the full-length LysR-type transcriptional regulator TsaR fromComamonas testosteroniT-2 and data-set analysis for a MIRAS structure-solution approach
  140. Erratum to “3D-Structure and function of strictosidine synthase – The key enzyme of monoterpenoid indole alkaloid biosynthesis” [Plant Physiol. Biochem. 46 (3) (2008) 340–355]
  141. Nonspecific base recognition mediated by water bridges and hydrophobic stacking in ribonuclease I from Escherichia coli
  142. 3D-Structure and function of strictosidine synthase – the key enzyme of monoterpenoid indole alkaloid biosynthesis
  143. ChemInform Abstract: Structural Biology in Plant Natural Product Biosynthesis—Architecture of Enzymes from Monoterpenoid Indole and Tropane Alkaloid Biosynthesis
  144. Purification, crystallization and preliminary X-ray diffraction analysis of aspartate semialdehyde dehydrogenase (Rv3708c) fromMycobacterium tuberculosis
  145. Automated technologies and novel techniques to accelerate protein crystallography for structural genomics
  146. Strictosidine Synthase:  Mechanism of a Pictet−Spengler Catalyzing Enzyme
  147. The Structure of a Full-length Response Regulator from Mycobacterium tuberculosis in a Stabilized Three-dimensional Domain-swapped, Activated State
  148. Structural studies on the 120 kDa motor subunit (HsdR) of the EcoR124I endonuclease from E.coli
  149. Molecular Architecture of Strictosidine Glucosidase: The Gateway to the Biosynthesis of the Monoterpenoid Indole Alkaloid Family
  150. Structure-Based Engineering of Strictosidine Synthase: Auxiliary for Alkaloid Libraries
  151. High-resolution structure of NodZ fucosyltransferase involved in the biosynthesis of the nodulation factor.
  152. RegX3 – a full-length response regulator that exhibits 3D-domain swapping
  153. Crystal Structures of a Poplar Thioredoxin Peroxidase that Exhibits the Structure of Glutathione Peroxidases: Insights into Redox-driven Conformational Changes
  154. Purification, crystallization and preliminary X-ray analysis of the HsdR subunit of theEcoR124I endonuclease fromEscherichia coli
  155. Chloroplasts Assemble the Major Subunit FaeG of Escherichia coli F4 (K88) Fimbriae to Strand-swapped Dimers
  156. Structure of the apo form of the catabolite control protein A (CcpA) fromBacillus megateriumwith a DNA-binding domain
  157. The molecular architecture of major enzymes from ajmaline biosynthetic pathway
  158. On the routine use of soft X-rays in macromolecular crystallography. Part IV. Efficient determination of anomalous substructures in biomacromolecules using longer X-ray wavelengths
  159. Structural biology in plant natural product biosynthesis—architecture of enzymes from monoterpenoid indole and tropane alkaloid biosynthesis
  160. A Catalytic Mechanism Revealed by the Crystal Structures of the Imidazolonepropionase from Bacillus subtilis
  161. Expression, purification, crystallization and preliminary X-ray analysis of perakine reductase, a new member of the aldo-keto reductase enzyme superfamily from higher plants
  162. Crystallization, preliminary crystallographic analysis and phasing of the thiosulfate-binding protein SoxY fromChlorobium limicolaf.thiosulfatophilum
  163. Auto-Rickshaw: an automated crystal structure determination pipeline as an efficient tool for fast validation of an X-ray diffraction experiment
  164. The X-ray Structure of the N-terminal Domain of PILB from Neisseria meningitidis Reveals a Thioredoxin-fold
  165. The Structural Basis of Signal Transduction for the Response Regulator PrrA from Mycobacterium tuberculosis
  166. The Structure of Rauvolfia serpentina Strictosidine Synthase Is a Novel Six-Bladed β-Propeller Fold in Plant Proteins
  167. Heterologous expression, purification, crystallization and preliminary X-ray analysis of raucaffricine glucosidase, a plant enzyme specifically involved inRauvolfiaalkaloid biosynthesis
  168. Structural and Functional Aspects of the Sensor Histidine Kinase PrrB from Mycobacterium tuberculosis
  169. On the routine use of soft X-rays in macromolecular crystallography. Part III. The optimal data-collection wavelength
  170. Structure of λ CII: Implications for recognition of direct-repeat DNA by an unusual tetrameric organization
  171. Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of DapB (Rv2773c) fromMycobacterium tuberculosis
  172. On the influence of the incident photon energy on the radiation damage in crystalline biological samples
  173. Crystal Structure of Vinorine Synthase, the First Representative of the BAHD Superfamily
  174. Auto-Rickshaw: an automated crystal structure determination platform as an efficient tool for the validation of an X-ray diffraction experiment
  175. The Crystal Structure of the Herpes Simplex Virus 1 ssDNA-binding Protein Suggests the Structural Basis for Flexible, Cooperative Single-stranded DNA Binding
  176. Structure Of The Complex Of Porcine Pancreatic Elastase In Complex With Cadmium Refined At 1.85 A Resolution (Crystal B)
  177. On the routine use of soft X-rays in macromolecular crystallography. Part II. Data-collection wavelength and scaling models
  178. Metal binding to porcine pancreatic elastase: calcium or not calcium
  179. Xenon derivatization of halide-soaked protein crystals
  180. Use of xenon in practice
  181. Phasing possibilities using different wavelengths with a xenon derivative
  182. Use of dry paraffin oil and Panjelly in the xenon derivatization of protein crystals
  183. Novel Cryo-cooling techniques
  184. Determinants of Backbone Packing in Globular Proteins: an Analysis of Spatial Neighbours
  185. THE IMPACT OF STRUCTURAL PROTEOMICS ON BIOTECHNOLOGY