All Stories

  1. Graphene-oxide surface chemistry governs protein adsorption: molecular docking insights
  2. Immobilisation of bovine serum albumin on graphene oxide through covalent and noncovalent interactions
  3. Mechanism of NanR transcriptional activation of sialic acid metabolism in Streptococcus pneumoniae
  4. Structural basis of isethionate transport by a TRAP transporter from a sulfate-reducing bacterium
  5. Author Correction: Macromolecular crystallography
  6. Macromolecular crystallography
  7. Peptide Bonds Unveiled: Enhancing Protein Structure Understanding
  8. Graphene-Based Impregnation into Polymeric Coating for Corrosion Resistance
  9. On the function of TRAP substrate-binding proteins: conformational variation of the sialic acid binding protein SiaP
  10. Structural characterization of PaaX, the main repressor of the phenylacetate degradation pathway in Escherichia coli W: A novel fold of transcription regulator proteins
  11. Ethoxylate Polymer-Based 96-Well Screen for Protein Crystallization
  12. Automated collection and screening capabilities on the Australian Synchrotron MX beamlines
  13. Streamlining fragment-based drug discovery pipeline at the Australian Synchrotron
  14. Characterization of a novel recombinant calcium-binding protein from Arca subcrenata and its anti-hepatoma activities in vitro and in vivo
  15. Engineering broad-spectrum inhibitors of inflammatory chemokines from subclass A3 tick evasins
  16. Repurposed inhibitor of bacterial dihydrodipicolinate reductase exhibits effective herbicidal activity
  17. Distinct Assemblies of Heterodimeric Cytokine Receptors Govern Stemness Programs in Leukemia
  18. TcpA from the Clostridium perfringens plasmid pCW3 is more closely related to the DNA translocase FtsK than to coupling proteins
  19. Crystal structure of a subtilisin-like autotransporter passenger domain reveals insights into its cytotoxic function
  20. Engineering Broad-spectrum Inhibitors of Inflammatory Chemokines from a New Family of Tick Evasins
  21. The role of auxiliary domains in modulating CHD4 activity suggests mechanistic commonality between enzyme families
  22. Phenol sensing in nature is modulated via a conformational switch governed by dynamic allostery
  23. Structural and functional characterization of Cas2 of CRISPR-Cas subtype I-C lacking the CRISPR component
  24. The role of auxiliary domains in modulating CHD4 activity suggests mechanistic commonality between enzyme families
  25. Phenol Sensing in Nature Modulated via a Conformational Switch Governed by Dynamic Allostery
  26. Crystal structure of the putative cell-wall lipoglycan biosynthesis protein LmcA from Mycobacterium smegmatis
  27. From bacteria to plants: a repurposing strategy in the pursuit for novel herbicides
  28. Structural characterization of the ANTAR antiterminator domain bound to RNA
  29. β-Methyltryptamine Provoking the Crucial Role of Strictosidine Synthase Tyr151-OH for Its Stereoselective Pictet−Spengler Reactions to Tryptoline-type Alkaloids
  30. Structural basis of dimerization and nucleic acid binding of human DBHS proteins NONO and PSPC1
  31. Graphene and Graphene Oxide as a Support for Biomolecules in the Development of Biosensors
  32. Data evaluation on the fly: Auto-Rickshaw on the MX beamlines of the Australian Synchrotron
  33. Uncovering the structures and mechanisms for the largest group of bacterial surface virulence factors
  34. Towards novel herbicide modes of action by inhibiting lysine biosynthesis in plants
  35. Salmonella enterica BcfH Is a Trimeric Thioredoxin-Like Bifunctional Enzyme with Both Thiol Oxidase and Disulfide Isomerase Activities
  36. Towards Novel Herbicide Modes of Action by Inhibiting Lysine Biosynthesis in Plants
  37. Helicobacter pylori Xanthine–Guanine–Hypoxanthine Phosphoribosyltransferase—A Putative Target for Drug Discovery against Gastrointestinal Tract Infections
  38. Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism
  39. Differential lysine‐mediated allosteric regulation of plant dihydrodipicolinate synthase isoforms
  40. Crystal structure and site-directed mutagenesis of circular bacteriocin plantacyclin B21AG reveals cationic and aromatic residues important for antimicrobial activity
  41. Crystal structure and site-directed mutagenesis of circular bacteriocin plantacyclin B21AG reveals cationic and aromatic residues important for antimicrobial activity
  42. Crystal structure of posnjakite formed in the first crystal water-cooling line of the ANSTO Melbourne Australian Synchrotron MX1 Double Crystal Monochromator
  43. Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism
  44. The basis for non-canonical ROK family function in the N-acetylmannosamine kinase from the pathogen Staphylococcus aureus
  45. Mis‐annotations of a promising antibiotic target in high‐priority gram‐negative pathogens
  46. Structural basis for differentiation between two classes of thiolase: Degradative vs biosynthetic thiolase
  47. Identification of two dihydrodipicolinate synthase isoforms from Pseudomonas aeruginosa that differ in allosteric regulation
  48. Stereocomplementary Chemoenzymatic Pictet–Spengler Reactions for Formation of Rare Azepino-indole Frameworks: Discovery of Antimalarial Compounds
  49. Combining random microseed matrix screening and the magic triangle for the efficient structure solution of a potential lysin from bacteriophage P68
  50. The Structural Basis for a Transition State That Regulates Pore Formation in a Bacterial Toxin
  51. Unique structural features of a bacterial autotransporter adhesin suggest mechanisms for interaction with host macromolecules
  52. Lanthanoid Heteroleptic Complexes with Cucurbit[5]uril and Dicarboxylate Ligands: From Discrete Structures to One-Dimensional and Two-Dimensional Polymers
  53. Crystal structure of TcpK in complex with oriT DNA of the antibiotic resistance plasmid pCW3
  54. Design of Protein-Based Biosensors for Selective Detection of Benzene Groups of Pollutants
  55. Beetle luciferases with naturally red- and blue-shifted emission
  56. Description of the MX2 research instrument at the Australian Synchrotron (ANSTO)
  57. NEW STRUCTURAL FEATURES REVEAL HOW BACTERIA STICK TO HOST SURFACES
  58. Molecular evolution of an oligomeric biocatalyst functioning in lysine biosynthesis
  59. Crystallographic analysis of β-ketoadipyl-CoA thiolase from Psedomonas putida
  60. Online automated structure solution from multiple data sets
  61. Structure-guided design of aromatic biosensors for water quality monitoring
  62. Structure of SgK223 pseudokinase reveals novel mechanisms of homotypic and heterotypic association
  63. Functional insights into the mode of DNA and ligand binding of the TetR family regulator TylP from Streptomyces fradiae
  64. Structure Guided Design of Protein Biosensors for Phenolic Pollutants
  65. Structure and Function of Cyanobacterial DHDPS and DHDPR
  66. Interdomain Conformational Changes Provide Allosteric Regulation en Route to Chorismate
  67. A critical examination of the recently reported crystal structures of the human SMN protein
  68. Structural basis of selective aromatic pollutant sensing by MopR, an NtrC family transcriptional regulator
  69. Structural Determinants Defining the Allosteric Inhibition of an Essential Antibiotic Target
  70. Structural Basis of Selective Aromatic Pollutant Sensing by the Effector Binding Domain of MopR, an NtrC Family Transcriptional Regulator
  71. Campylobacter jejuni adenosine triphosphate phosphoribosyltransferase is an active hexamer that is allosterically controlled by the twisting of a regulatory tail
  72. A crystallographic study of human NONO (p54nrb): overcoming pathological problems with purification, data collection and noncrystallographic symmetry
  73. Cover Picture: Radiation Damage and Racemic Protein Crystallography Reveal the Unique Structure of the GASA/Snakin Protein Superfamily (Angew. Chem. Int. Ed. 28/2016)
  74. Titelbild: Radiation Damage and Racemic Protein Crystallography Reveal the Unique Structure of the GASA/Snakin Protein Superfamily (Angew. Chem. 28/2016)
  75. Radiation Damage and Racemic Protein Crystallography Reveal the Unique Structure of the GASA/Snakin Protein Superfamily
  76. Radiation Damage and Racemic Protein Crystallography Reveal the Unique Structure of the GASA/Snakin Protein Superfamily
  77. Psychromonas ingrahamii diaminopimelate decarboxylase with LLP
  78. Combining cross-crystal averaging and MRSAD to phase a 4354-amino-acid structure
  79. Stonefish toxin defines an ancient branch of the perforin-like superfamily
  80. Cyclic Peptides Incorporating Phosphotyrosine Mimetics as Potent and Specific Inhibitors of the Grb7 Breast Cancer Target
  81. Automated structure solution from multiple data sets
  82. Functional Coupling of Duplex Translocation to DNA Cleavage in a Type I Restriction Enzyme
  83. A step towards long-wavelength protein crystallography: subjecting protein crystals to a vacuum
  84. MX1: a bending-magnet crystallography beamline serving both chemical and macromolecular crystallography communities at the Australian Synchrotron
  85. Quaternary Structure Analyses of an Essential Oligomeric Enzyme
  86. The Crystal Structure of a Homodimeric Pseudomonas Glyoxalase I Enzyme Reveals Asymmetric Metallation Commensurate with Half‐of‐Sites Activity
  87. Crystal structure of Clostridium acetobutylicum aspartate kinase (CaAk): An important allosteric enzyme for amino acids production
  88. Ligand structures of synthetic deoxa-pyranosylamines with raucaffricine and strictosidine glucosidases provide structural insights into their binding and inhibitory behaviours
  89. Post-translational modification and extended glycosylation pattern of a plant latex peroxidase of native source characterized by X-ray crystallography
  90. Alternative phasing method in macromolecular crystallography
  91. Chemical Crystallography at the Australian Synchrotron MX Beamlines
  92. The structure of an ABC toxin particle determined by X-ray crystallography and single particle EM.
  93. The Three-dimensional Structure of the Extracellular Adhesion Domain of the Sialic Acid-binding Adhesin SabA from Helicobacter pylori
  94. WXG100 Protein Superfamily Consists of Three Subfamilies and Exhibits an α-Helical C-Terminal Conserved Residue Pattern
  95. Importance of Hydrophobic Cavities in Allosteric Regulation of Formylglycinamide Synthetase: Insight from Xenon Trapping and Statistical Coupling Analysis
  96. Importance of Hydrophobic Cavities in Allosteric Regulation of Formylglycinamide Synthetase: Insight from Xenon Trapping and Statistical Coupling Analysis
  97. Importance of Hydrophobic Cavities in Allosteric Regulation of Formylglycinamide Synthetase: Insight from Xenon Trapping and Statistical Coupling Analysis
  98. Cloning to crystallization of dihydrodipicolinate synthase from the intracellular pathogenLegionella pneumophila
  99. Phasing selenomethionine proteins using UV-induced radiation damage
  100. Putative dioxygen-binding sites and recognition of tigecycline and minocycline in the tetracycline-degrading monooxygenase TetX
  101. The BC component of ABC toxins is an RHS-repeat-containing protein encapsulation device
  102. High speed X-ray analysis of plant enzymes at room temperature
  103. Cyanuric acid hydrolase: evolutionary innovation by structural concatenation
  104. High speed X-ray analysis of plant enzymes at room temperature
  105. In-house UV radiation-damage-induced phasing of selenomethionine-labeled protein structures
  106. High-resolution structure ofBombyx morilipoprotein 7: crystallographic determination of the identity of the protein and its potential role in detoxification
  107. Structural insight in histo‐blood group binding by the F18 fimbrial adhesin FedF
  108. Purification, crystallization and preliminary crystallographic analysis of banyan peroxidase
  109. The crystal structure of the CRISPR-associated protein Csn2 from Streptococcus agalactiae
  110. Structural basis for modification of flavonol and naphthol glucoconjugates by Nicotiana tabacum malonyltransferase (NtMaT1)
  111. Formylglycinamide ribonucleotide amidotransferase fromSalmonella typhimurium: role of ATP complexation and the glutaminase domain in catalytic coupling
  112. Nonprocessive [2 + 2]e - off-loading reductase domains from mycobacterial nonribosomal peptide synthetases
  113. Correction to Scaffold Tailoring by a Newly Detected Pictet–Spenglerase Activity of Strictosidine Synthase: From the Common Tryptoline Skeleton to the Rare Piperazino-indole Framework
  114. Crystal Structure of Perakine Reductase, Founding Member of a Novel Aldo-Keto Reductase (AKR) Subfamily That Undergoes Unique Conformational Changes during NADPH Binding
  115. Crystal structure of NAD+-dependent Peptoniphilus asaccharolyticus glutamate dehydrogenase reveals determinants of cofactor specificity
  116. The sensor region of the ubiquitous cytosolic sensor kinase, PdtaS, contains PAS and GAF domain sensing modules
  117. Scaffold Tailoring by a Newly Detected Pictet–Spenglerase Activity of Strictosidine Synthase: From the Common Tryptoline Skeleton to the Rare Piperazino-indole Framework
  118. The impact of structural biology on alkaloid biosynthesis research
  119. Current methods in structural proteomics and its applications in biological sciences
  120. Structures of Alkaloid Biosynthetic Glucosidases Decode Substrate Specificity
  121. Structures of Alkaloid Biosynthetic Glucosidases Decode Substrate Specificity
  122. Structures of Alkaloid Biosynthetic Glucosidases Decode Substrate Specificity
  123. Insights into ubiquitin-conjugating enzyme/ co-activator interactions from the structure of the Pex4p:Pex22p complex
  124. Structures of Alkaloid Biosynthetic Glucosidases Decode Substrate Specificity
  125. Structural Insights into the Mechanism of Protein O-Fucosylation
  126. Phasing selenomethionine proteins using UV induced radiation damage
  127. S-SAD phasing of proteinO-fucosyltransferase-1 at a resolution of 2.6 Å in the monoclinic space groupC2
  128. On the routine use of soft X-rays in macromolecular crystallography. Part V. Molecular replacement and anomalous scattering
  129. Crystallization and preliminary X-ray crystallographic studies of an oligomeric species of a refolded C39 peptidase-like domain of theEscherichia coliABC transporter haemolysin B
  130. Additional phase information from UV damage of selenomethionine labelled proteins
  131. Structural Basis for the Oxidation of Protein-bound Sulfur by the Sulfur Cycle Molybdohemo-Enzyme Sulfane Dehydrogenase SoxCD
  132. Structural Characterization of the Multidomain Regulatory Protein Rv1364c from Mycobacterium tuberculosis
  133. Single isomorphous replacement phasing of selenomethionine-containing proteins using UV-induced radiation damage
  134. Update on the tutorial for learning and teaching macromolecular crystallography
  135. Update on the tutorial for learning and teaching macromolecular crystallography
  136. Expression, purification and X-ray analysis of 1,3-propanediol dehydrogenase (Aq_1145) fromAquifex aeolicusVF5
  137. On the combination of molecular replacement and single-wavelength anomalous diffraction phasing for automated structure determination
  138. Crystal Structure of Polyneuridine Aldehyde Esterase Complexed with 16-epi-Vellosimine
  139. Crystal structure of polyneuridine aldehyde esterase
  140. Structure of the C-terminal domain of nsp4 from Feline Coronavirus
  141. Auto-Rickshaw: a tool for online validation of X-ray diffraction experiment
  142. Structure of the C-terminal domain of NSP4 from feline infection peritonitis virus
  143. Structure of the C-terminal domain of nsp4 from feline coronavirus
  144. Strukturbasis und Enzymmechanismus der Biosynthese von C9‐ aus C10‐monoterpenoiden Indol‐Alkaloiden
  145. Structural Basis and Enzymatic Mechanism of the Biosynthesis of C9‐ from C10‐Monoterpenoid Indole Alkaloids
  146. The F4 fimbrial chaperone FaeE is stable as a monomer that does not require self-capping of its pilin-interactive surfaces
  147. Structural analysis reveals DNA binding properties of Rv2827c, a hypothetical protein from Mycobacterium tuberculosis
  148. The impact of Structural Proteomics on Biotechnology
  149. Structure of the motor subunit of type I restriction-modification complex EcoR124I
  150. A tutorial for learning and teaching macromolecular crystallography
  151. Structural Basis for Parasite-Specific Functions of the Divergent Profilin of Plasmodium falciparum
  152. Purification, crystallization and X-ray diffraction analysis of pavineN-methyltransferase fromThalictrum flavum
  153. C4-Dicarboxylates Sensing Mechanism Revealed by the Crystal Structures of DctB Sensor Domain
  154. A tutorial for learning and teaching macromolecular crystallography
  155. Auto-Rickshaw: an online tool for validation of an X-ray diffraction experiment
  156. High crystallizability under air-exclusion conditions of the full-length LysR-type transcriptional regulator TsaR fromComamonas testosteroniT-2 and data-set analysis for a MIRAS structure-solution approach
  157. Erratum to “3D-Structure and function of strictosidine synthase – The key enzyme of monoterpenoid indole alkaloid biosynthesis” [Plant Physiol. Biochem. 46 (3) (2008) 340–355]
  158. Nonspecific base recognition mediated by water bridges and hydrophobic stacking in ribonuclease I from Escherichia coli
  159. 3D-Structure and function of strictosidine synthase – the key enzyme of monoterpenoid indole alkaloid biosynthesis
  160. ChemInform Abstract: Structural Biology in Plant Natural Product Biosynthesis—Architecture of Enzymes from Monoterpenoid Indole and Tropane Alkaloid Biosynthesis
  161. Purification, crystallization and preliminary X-ray diffraction analysis of aspartate semialdehyde dehydrogenase (Rv3708c) fromMycobacterium tuberculosis
  162. Automated technologies and novel techniques to accelerate protein crystallography for structural genomics
  163. Strictosidine Synthase:  Mechanism of a Pictet−Spengler Catalyzing Enzyme
  164. The Structure of a Full-length Response Regulator from Mycobacterium tuberculosis in a Stabilized Three-dimensional Domain-swapped, Activated State
  165. Structural studies on the 120 kDa motor subunit (HsdR) of the EcoR124I endonuclease from E.coli
  166. Molecular Architecture of Strictosidine Glucosidase: The Gateway to the Biosynthesis of the Monoterpenoid Indole Alkaloid Family
  167. Structure-Based Engineering of Strictosidine Synthase: Auxiliary for Alkaloid Libraries
  168. High-resolution structure of NodZ fucosyltransferase involved in the biosynthesis of the nodulation factor.
  169. RegX3 – a full-length response regulator that exhibits 3D-domain swapping
  170. Crystal Structures of a Poplar Thioredoxin Peroxidase that Exhibits the Structure of Glutathione Peroxidases: Insights into Redox-driven Conformational Changes
  171. Purification, crystallization and preliminary X-ray analysis of the HsdR subunit of theEcoR124I endonuclease fromEscherichia coli
  172. Chloroplasts Assemble the Major Subunit FaeG of Escherichia coli F4 (K88) Fimbriae to Strand-swapped Dimers
  173. Structure of the apo form of the catabolite control protein A (CcpA) fromBacillus megateriumwith a DNA-binding domain
  174. The molecular architecture of major enzymes from ajmaline biosynthetic pathway
  175. On the routine use of soft X-rays in macromolecular crystallography. Part IV. Efficient determination of anomalous substructures in biomacromolecules using longer X-ray wavelengths
  176. Structural biology in plant natural product biosynthesis—architecture of enzymes from monoterpenoid indole and tropane alkaloid biosynthesis
  177. A Catalytic Mechanism Revealed by the Crystal Structures of the Imidazolonepropionase from Bacillus subtilis
  178. Expression, purification, crystallization and preliminary X-ray analysis of perakine reductase, a new member of the aldo-keto reductase enzyme superfamily from higher plants
  179. Crystallization, preliminary crystallographic analysis and phasing of the thiosulfate-binding protein SoxY fromChlorobium limicolaf.thiosulfatophilum
  180. Auto-Rickshaw: an automated crystal structure determination pipeline as an efficient tool for fast validation of an X-ray diffraction experiment
  181. The X-ray Structure of the N-terminal Domain of PILB from Neisseria meningitidis Reveals a Thioredoxin-fold
  182. The Structural Basis of Signal Transduction for the Response Regulator PrrA from Mycobacterium tuberculosis
  183. The Structure of Rauvolfia serpentina Strictosidine Synthase Is a Novel Six-Bladed β-Propeller Fold in Plant Proteins
  184. Heterologous expression, purification, crystallization and preliminary X-ray analysis of raucaffricine glucosidase, a plant enzyme specifically involved inRauvolfiaalkaloid biosynthesis
  185. Structural and Functional Aspects of the Sensor Histidine Kinase PrrB from Mycobacterium tuberculosis
  186. On the routine use of soft X-rays in macromolecular crystallography. Part III. The optimal data-collection wavelength
  187. Structure of λ CII: Implications for recognition of direct-repeat DNA by an unusual tetrameric organization
  188. Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of DapB (Rv2773c) fromMycobacterium tuberculosis
  189. On the influence of the incident photon energy on the radiation damage in crystalline biological samples
  190. Crystal Structure of Vinorine Synthase, the First Representative of the BAHD Superfamily
  191. Auto-Rickshaw: an automated crystal structure determination platform as an efficient tool for the validation of an X-ray diffraction experiment
  192. The Crystal Structure of the Herpes Simplex Virus 1 ssDNA-binding Protein Suggests the Structural Basis for Flexible, Cooperative Single-stranded DNA Binding
  193. Structure Of The Complex Of Porcine Pancreatic Elastase In Complex With Cadmium Refined At 1.85 A Resolution (Crystal B)
  194. On the routine use of soft X-rays in macromolecular crystallography. Part II. Data-collection wavelength and scaling models
  195. Metal binding to porcine pancreatic elastase: calcium or not calcium
  196. Xenon derivatization of halide-soaked protein crystals
  197. Use of xenon in practice
  198. Phasing possibilities using different wavelengths with a xenon derivative
  199. Use of dry paraffin oil and Panjelly in the xenon derivatization of protein crystals
  200. Novel Cryo-cooling techniques
  201. Determinants of Backbone Packing in Globular Proteins: an Analysis of Spatial Neighbours
  202. THE IMPACT OF STRUCTURAL PROTEOMICS ON BIOTECHNOLOGY