All Stories

  1. Direct Hydroxymethylation of C=N Double Bonds

    Article • Letters in Organic Chemistry, April 2018, Bentham Science Publishers

    Professor Pedro Merino, Tomás Tejero

  2. Organocatalytic Enantioselective Synthesis of Trifluoromethyl-Containing Tetralin Derivatives by Sequential (Hetero)Michael Reaction-Intramolecular Nitrone Cycloaddition

    Article • Advanced Synthesis & Catalysis, November 2017, Wiley

    Professor Pedro Merino

  3. A Case Study of Thiourea-Assisted Iminium Formation by Hydroxyl Anion Binding: Kinetic, Spectroscopic and Computational Evidences

    Article • Advanced Synthesis & Catalysis, September 2017, Wiley

    Professor Pedro Merino

  4. Recent Advances in the Preparation of Enantiomerically Pure Hydroxylamines from Nitrones

    Article • Current Organic Synthesis, October 2016, Bentham Science Publishers

    Professor Pedro Merino

  5. Design and Synthesis of Dopaminergic Agonists

    Article • Current Medicinal Chemistry, September 2016, Bentham Science Publishers

    Professor Pedro Merino

  6. Rational Design of Glycomimetic Compounds Targeting theSaccharomyces cerevisiaeTransglycosylase Gas2

    Article • Chemical Biology & Drug Design, September 2015, Wiley

    Professor Pedro Merino

  7. Recent Advances on the Enantioselective Synthesis of C-Nucleosides Inhibitors of Inosine Monophosphate Dehydrogenase (IMPDH)

    Article • Current Topics in Medicinal Chemistry, May 2014, Bentham Science Publishers

    Professor Pedro Merino

  8. [2n2π + 2n2π] Cycloadditions: an alternative to forbidden [4π + 4π] processes. The case of nitrone dimerization

    Article • Organic & Biomolecular Chemistry, January 2014, Royal Society of Chemistry

    Professor Pedro Merino

  9. Highly diastereoselective 1,3-dipolar cycloadditions of chiral non-racemic nitrones to 1,2-diaza-1,3-dienes: an experimental and computational investigation

    Article • Organic & Biomolecular Chemistry, January 2014, Royal Society of Chemistry

    Professor Pedro Merino

  10. Synthesis of O- and C-glycosides derived from β-(1,3)-d-glucans

    Article • Carbohydrate Research, December 2013, Elsevier

    Professor Pedro Merino

  11. Stereoselective 1,3-dipolar cycloadditions of nitrones derived from amino acids. Asymmetric synthesis of N-(alkoxycarbonylmethyl)-3-hydroxypyrrolidin-2-ones

    Article • Tetrahedron, November 2013, Elsevier

    Professor Pedro Merino, Venerando Pistarà

  12. Evasive Neutral 2-Aza-Cope Rearrangements. Kinetic and Computational Studies with Cyclic Nitrones

    Article • European Journal of Organic Chemistry, July 2013, Wiley

    Professor Pedro Merino

  13. Chemical Synthesis of Nucleoside Analogues

    Article • February 2013, Wiley

    Professor Pedro Merino

  14. Recent Advances in the Chemical Synthesis of Aza-Nucleosides

    Article • February 2013, Wiley

    Professor Pedro Merino

  15. Chemical Synthesis of Conformationally Constrained PNA Monomers

    Article • February 2013, Wiley

    Professor Pedro Merino

  16. The High Selectivity of the Cp2ZrHCl Reducing Agent for Imides: A Combined Experimental and Theoretical Study on γ-Lactam and Isoxazolidinone Derivatives

    Article • European Journal of Organic Chemistry, November 2012, Wiley

    Professor Pedro Merino

  17. Recent Progress on Fucosyltransferase Inhibitors

    Article • Mini-Reviews in Medicinal Chemistry, November 2012, Bentham Science Publishers

    Professor Pedro Merino

  18. Dual reactivity of O-α-allenyl esters under palladium(0) catalysis: From carbopalladation/allylic alkylation domino sequence to decarboxylative allenylation

    Article • Journal of Organometallic Chemistry, September 2012, Elsevier

    Professor Pedro Merino

  19. Highly stereoselective synthesis of imino-C-di- and trisaccharides as hydrolytically stable glycomimetics

    Article • Tetrahedron, August 2012, Elsevier

    Professor Pedro Merino

  20. Truncated Reverse Isoxazolidinyl Nucleosides: A New Class of Allosteric HIV-1 Reverse Transcriptase Inhibitors

    Article • ChemMedChem, February 2012, Wiley

    Professor Pedro Merino

  21. Stereoselective Hydride Transfer by Aryl-Alcohol Oxidase, a Member of the GMC Superfamily

    Article • ChemBioChem, January 2012, Wiley

    Professor Pedro Merino

  22. CROSS-COUPLING REACTIONS FOR THE SYNTHESIS OF C-GLYCOSIDES AND RELATED COMPOUNDS

    Article • Heterocycles, January 2012, Japan Institute of Heterocyclic Chemistry

    Professor Pedro Merino

  23. Water-compatible one-pot organocatalytic asymmetric synthesis of cyclic nitrones. Application in intramolecular 1,3-dipolar cycloadditions

    Article • Tetrahedron Letters, November 2011, Elsevier

    Professor Pedro Merino

  24. High-yield synthesis of pyrrolidinyl PNA monomers

    Article • Tetrahedron Letters, November 2011, Elsevier

    Professor Pedro Merino, Venerando Pistarà

  25. Structural Insights into the Mechanism of Protein O-Fucosylation

    Article • PLoS ONE, September 2011, PLOS

    Professor Pedro Merino

  26. Nitrone Ylides: Two Possible 1,3-Dipolar Cycloadditions but Only One Stepwise Formation of all-cis-5-Aryl-2,3,5-trisubstituted N-Hydroxypyrrolidines

    Article • European Journal of Organic Chemistry, September 2011, Wiley

    Professor Pedro Merino

  27. Mannich-Type Reactions of Nitrones, Oximes, and Hydrazones

    Article • Synlett, August 2011, Thieme Publishing Group

    Professor Pedro Merino

  28. Organocatalytic Activation of Imines and Related Compounds Through Hydrogen-Bond Interactions

    Article • Current Organic Chemistry, July 2011, Bentham Science Publishers

    Professor Pedro Merino

  29. Sequential Nucleophilic Addition/Intramolecular Cycloaddition to Chiral Nonracemic Cyclic Nitrones: A Highly Stereoselective Approach to Polyhydroxynortropane Alkaloids

    Article • The Journal of Organic Chemistry, May 2011, American Chemical Society (ACS)

    Professor Pedro Merino

  30. Thiourea catalyzed organocatalytic enantioselective Michael addition of diphenyl phosphite to nitroalkenes

    Article • Organic & Biomolecular Chemistry, January 2011, Royal Society of Chemistry

    Professor Pedro Merino

  31. Organocatalyzed Michael Addition Reaction by Novel (2R,3aS,7aS)-Octa-hydroindole-2-carboxylic Acid, a New Fused Proline

    Article • Synlett, January 2011, Thieme Publishing Group

    Professor Pedro Merino

  32. Experimental and theoretical studies on Mannich-type reactions of chiral non-racemic N-(benzyloxyethyl) nitrones

    Article • Tetrahedron Asymmetry, December 2010, Elsevier

    Professor Pedro Merino

  33. Asymmetric organocatalytic synthesis of γ-nitrocarbonyl compounds through Michael and Domino reactions

    Article • Tetrahedron Asymmetry, November 2010, Elsevier

    Professor Pedro Merino

  34. Tunable Diastereoselection of Biased Rigid Systems by Lewis Acid Induced Conformational Effects: A Rationalization of the Vinylation of Cyclic Nitrones En Route to Polyhydroxylated Pyrrolidines

    Article • Chemistry - A European Journal, August 2010, Wiley

    Professor Pedro Merino

  35. Expanding the Limits of Organoboron Chemistry: Synthesis of Functionalized Arylboronates

    Article • Angewandte Chemie International Edition, July 2010, Wiley

    Professor Pedro Merino

  36. Chemical Synthesis of Heterocyclic−Sugar Nucleoside Analogues

    Article • Chemical Reviews, June 2010, American Chemical Society (ACS)

    Professor Pedro Merino

  37. Synthesis of d-arabinose-derived polyhydroxylated pyrrolidine, indolizidine and pyrrolizidine alkaloids. Total synthesis of hyacinthacine A2

    Article • Tetrahedron, February 2010, Elsevier

    Professor Pedro Merino

  38. Intramolecular 1,3-dipolar cycloaddition of N-alkenyl nitrones en route to glycosyl piperidines

    Article • Tetrahedron Letters, December 2009, Elsevier

    Professor Pedro Merino

  39. Synthesis of N-(Benzyloxyethyl)- and N-(Alkoxycarbonylmethyl)nitrones

    Article • Synthesis, November 2009, Thieme Publishing Group

    Professor Pedro Merino

  40. Enantioselective Organocatalytic Diels-Alder Reactions

    Article • Synthesis, November 2009, Thieme Publishing Group

    Professor Pedro Merino

  41. The Role of the Indole in Important Organocatalytic Enantioselective Friedel-Crafts Alkylation Reactions

    Article • Current Organic Chemistry, November 2009, Bentham Science Publishers

    Professor Pedro Merino

  42. Chemistry and Biology of Iminosugar Di- and Oligosaccharides

    Article • Current Chemical Biology, September 2009, Bentham Science Publishers

    Professor Pedro Merino

  43. Stereoselective Synthesis and Biological Evaluations of Novel 3′-Deoxy-4′-azaribonucleosides as Inhibitors of Hepatitis C Virus RNA Replication

    Article • Journal of Medicinal Chemistry, July 2009, American Chemical Society (ACS)

    Professor Antonio Rescifina, Professor Pedro Merino

  44. Catalytic Enantioselective Aza‐Henry Reactions

    Article • European Journal of Organic Chemistry, May 2009, Wiley

    Professor Pedro Merino

  45. Organocatalyzed Strecker reactions

    Article • Tetrahedron, February 2009, Elsevier

    Professor Pedro Merino

  46. Exploring Nitrone Chemistry: Towards the Enantiodivergent Synthesis of 6-Substituted 4-Hydroxypipecolic Acid Derivatives

    Article • European Journal of Organic Chemistry, August 2008, Wiley

    Professor Pedro Merino

  47. Catalytic Enantioselective Hydrophosphonylation of Aldehydes and Imines

    Article • Advanced Synthesis & Catalysis, June 2008, Wiley

    Professor Pedro Merino

  48. Nucleophilic Additions to Cyclic Nitrones en Route to Iminocyclitols – Total Syntheses of DMDP, 6-deoxy-DMDP, DAB-1, CYB-3, Nectrisine, and Radicamine B

    Article • European Journal of Organic Chemistry, June 2008, Wiley

    Professor Pedro Merino

  49. Current Developments in the Synthesis and Biological Activity of Aza-C-Nucleosides:Immucillins and Related Compounds

    Article • Current Medicinal Chemistry, April 2008, Bentham Science Publishers

    Professor Pedro Merino

  50. Nucleophilic Additions and Redox Reactions of Polyhydroxypyrroline N -Oxides on the Way to Pyrrolidine Alkaloids: Total Synthesis of Radicamine B

    Article • Synlett, October 2007, Thieme Publishing Group

    Professor Pedro Merino

  51. Furan Oxidations in Organic Synthesis: Recent Advances and Applications

    Article • Current Organic Chemistry, August 2007, Bentham Science Publishers

    Professor Pedro Merino

  52. 3-(Aminomethyl)-2-(carboxymethyl)isoxazolidinyl nucleosides: building blocks for peptide nucleic acid analogues

    Article • Tetrahedron Asymmetry, July 2007, Elsevier

    Professor Pedro Merino

  53. Experimental and theoretical evidences of 2-aza-Cope rearrangement of nitrones

    Article • Tetrahedron Letters, May 2007, Elsevier

    Professor Pedro Merino

  54. Hydroxylamine Oxygen as Nucleophile in Palladium(0)- and Palladium(II)-Catalyzed Allylic Alkylation: A Novel Access to Isoxazolidines

    Article • Synlett, April 2007, Thieme Publishing Group

    Professor Pedro Merino

  55. A DFT study on the 1,3-dipolar cycloaddition reactions of C-(hetaryl) nitrones with methyl acrylate and vinyl acetate

    Article • Tetrahedron, February 2007, Elsevier

    Professor Antonio Rescifina, Professor Pedro Merino

  56. A DFT Study of the Molecular Mechanisms of the Nucleophilic Addition of Ester-Derived Lithium Enolates and Silyl Ketene Acetals to Nitrones: Effects of the Lewis Acid Catalyst

    Article • European Journal of Organic Chemistry, August 2006, Wiley

    Professor Pedro Merino

  57. Stereoselective synthesis of pyrrolidinyl glycines from nitrones: complementarity of nucleophilic addition and 1,3-dipolar cycloaddition

    Article • Tetrahedron Letters, July 2006, Elsevier

    Professor Pedro Merino

  58. Enantiodivergent Synthesis of d - and l - e rythro -Sphingosines through Mannich-Type Reactions of N -Benzyl-2,3- O -isopropylidene- d -glyceraldehyde Nitrone

    Article • The Journal of Organic Chemistry, June 2006, American Chemical Society (ACS)

    Professor Pedro Merino

  59. High stereocontrol in the allylation of chiral non-racemic α-alkoxy and α-amino nitrones

    Article • Tetrahedron Letters, May 2006, Elsevier

    Professor Pedro Merino

  60. Heterocyclic Nucleosides: Chemical Synthesis and Biological Properties

    Article • Current Medicinal Chemistry, March 2006, Bentham Science Publishers

    Professor Pedro Merino

  61. An efficient approach to enantiomeric isoxazolidinyl analogues of tiazofurin based on nitrone cycloadditions

    Article • Tetrahedron Asymmetry, November 2005, Elsevier

    Professor Pedro Merino

  62. Zinc(II) Triflate-Controlled 1,3-Dipolar Cycloadditions of C -(2-Thiazolyl)nitrones:  Application to the Synthesis of a Novel Isoxazolidinyl Analogue of Tiazofurin

    Article • The Journal of Organic Chemistry, October 2005, American Chemical Society (ACS)

    Professor Antonio Rescifina, Professor Pedro Merino

  63. Stereoselective Allylation Reactions of Imines and Related Compounds

    Article • Current Organic Synthesis, October 2005, Bentham Science Publishers

    Professor Pedro Merino

  64. Enantioselective 1,3-Dipolar Cycloaddition of Nitrones to Methacrolein Catalyzed by (η 5 -C 5 Me 5 )M{( R )-Prophos} Containing Complexes (M = Rh, Ir; ( R )-Prophos = 1,2-bis(Diphenylphosphino)propane):  On the Origin of the Enantioselectivity

    Article • Journal of the American Chemical Society, September 2005, American Chemical Society (ACS)

    Professor Pedro Merino

  65. New Concise Total Synthesis of (+)-Lentiginosine and Some Structural Analogues

    Article • The Journal of Organic Chemistry, August 2005, American Chemical Society (ACS)

    Professor Pedro Merino

  66. New developments in nucleophilic additions to nitrones

    Article • Comptes Rendus Chimie, May 2005, Elsevier

    Professor Pedro Merino

  67. Nucleophilic additions of lithiated allylphenylsulfone to nitrones: experimental and theoretical investigations

    Article • Tetrahedron, March 2005, Elsevier

    Professor Pedro Merino

  68. Straightforward synthesis of enantiopure 2-aminomethyl and 2-hydroxymethyl pyrrolidines with complete stereocontrol

    Article • Tetrahedron Letters, February 2005, Elsevier

    Professor Pedro Merino

  69. Organocatalyzed Asymmetricα-Aminoxylation of Aldehydes and Ketones—An Efficient Access to Enantiomerically Pureα-Hydroxycarbonyl Compounds, Diols, and Even Amino Alcohols

    Article • Angewandte Chemie International Edition, June 2004, Wiley

    Professor Pedro Merino

  70. Organometallic gold(III) and gold(I) complexes as catalysts for the 1,3-dipolar cycloaddition to nitrones: synthesis of novel gold–nitrone derivatives

    Article • Journal of Organometallic Chemistry, May 2004, Elsevier

    Professor Pedro Merino

  71. The Complete Characterization of a Rhodium Lewis Acid−Dipolarophile Complex as an Intermediate for the Enantioselective Catalytic 1,3-Dipolar Cycloaddition of C , N -Diphenylnitrone to Methacrolein

    Article • Journal of the American Chemical Society, March 2004, American Chemical Society (ACS)

    Professor Pedro Merino

  72. Fully Stereoselective Nucleophilic Addition to a Novel Chiral PyrrolineN-Oxide: Total Syntheses of (2S,3R)-3-Hydroxy-3-methylproline and Its (2R)-Epimer

    Article • European Journal of Organic Chemistry, February 2004, Wiley

    Professor Pedro Merino

  73. Diastereoselective synthesis of homo-N,O-nucleosides

    Article • Tetrahedron, January 2004, Elsevier

    Professor Antonio Rescifina, Professor Pedro Merino

  74. 1,3-Dipolar cycloaddition between N-benzyl-C-glycosyl nitrones and methyl acrylate en route to glycosyl pyrrolidines

    Article • Tetrahedron Asymmetry, November 2003, Elsevier

    Professor Pedro Merino, Dr Santiago Franco

  75. Diastereo- and Enantioselective Synthesis of 1′-C-BranchedN,O-Nucleosides

    Article • Nucleosides Nucleotides & Nucleic Acids, October 2003, Taylor & Francis

    Professor Antonio Rescifina, Professor Pedro Merino

  76. Iterative Organometallic Addition to Chiral Hydroxylated Cyclic Nitrones: Highly Stereoselective Syntheses of α,α‘- and α,α-Substituted Hydroxypyrrolidines

    Article • Organic Letters, October 2003, American Chemical Society (ACS)

    Professor Pedro Merino

  77. Enantioselective synthesis of N,O-psiconucleosides

    Article • Tetrahedron Asymmetry, August 2003, Elsevier

    Professor Antonio Rescifina, Professor Pedro Merino

  78. Isoxazolidine analogues of pseudouridine: a new class of modified nucleosides

    Article • Tetrahedron, June 2003, Elsevier

    Professor Antonio Rescifina, Professor Pedro Merino

  79. A DFT study on the 1,3-dipolar cycloaddition reactions of C-(methoxycarbonyl)-N-methyl nitrone with methyl acrylate and vinyl acetate

    Article • Tetrahedron, May 2003, Elsevier

    Professor Antonio Rescifina, Professor Pedro Merino

  80. A comparative study of the stereoselective addition of trimethylsilyl cyanide and diethylaluminum cyanide to chiral cyclic nitrones

    Article • Tetrahedron Asymmetry, February 2003, Elsevier

    Professor Pedro Merino

  81. An investigation of the Lewis acid mediated 1,3-dipolar cycloaddition between N-benzyl-C-(2-pyridyl)nitrone and allylic alcohol. Direct entry to isoxazolidinyl C-nucleosidesElectronic supplementary information (ESI) available: optimized geometries (PDB...

    Article • Organic & Biomolecular Chemistry, January 2003, Royal Society of Chemistry

    Professor Pedro Merino

  82. Enantioselective synthesis of 4-hydroxy-d-pyroglutamic acid derivatives by an asymmetric 1,3-dipolar cycloaddition

    Article • Tetrahedron Asymmetry, February 2002, Elsevier

    Professor Antonio Rescifina, Professor Pedro Merino

  83. Experimental and theoretical study of the 1,3-dipolar cycloaddition between d-glyceraldehyde nitrones and acrylates. Diastereoselective approach to 4-hydroxy pyroglutamic acid derivatives

    Article • Tetrahedron Asymmetry, February 2002, Elsevier

    Professor Pedro Merino

  84. Understanding the high diastereofacial discrimination in nucleophilic additions to nitrones: the first ab initio study on the nucleophilic addition reactions of chiral nitrones with Grignard reagents

    Article • Tetrahedron, September 2001, Elsevier

    Professor Pedro Merino

  85. Stereodivergent Approaches to the Synthesis of Isoxazolidine Analogues of α-Amino Acid Nucleosides. Total Synthesis of Isoxazolidinyl Deoxypolyoxin C and Uracil Polyoxin C †

    Article • The Journal of Organic Chemistry, September 2000, American Chemical Society (ACS)

    Professor Pedro Merino

  86. Stereoselective synthesis of l-isoxazolidinyl thymidine from N-benzyl-1,2-di-O-isopropylidene-d-glyceraldehyde nitrone (BIGN)

    Article • Tetrahedron Asymmetry, April 2000, Elsevier

    Professor Pedro Merino

  87. 1,3-Dipolar Cycloaddition of Furfuryl Nitrones with Acrylates. A Convenient Approach to Protected 4-Hydroxypyroglutamic Acids

    Article • The Journal of Organic Chemistry, March 2000, American Chemical Society (ACS)

    Professor Pedro Merino