All Stories

  1. Identifying and understanding factors that affect the translation of therapies from the laboratory to patients: a study protocol

    Article • F1000Research, June 2020, Faculty of 1000, Ltd.

    Professor Malcolm R Macleod, David Ripsman, Manoj Lalu, Lindsey Sikora, Dr C.Glenn Begley

  2. Real-world Independent Testing of e-ASPECTS Software (RITeS): statistical analysis plan

    Article • AMRC Open Research, April 2020, Faculty of 1000, Ltd.

    Professor Malcolm R Macleod

  3. Systematic review of guidelines for internal validity in the design, conduct and analysis of preclinical biomedical experiments involving laboratory animals

    Article • BMJ Open Science, April 2020, BMJ

    Professor Malcolm R Macleod

  4. Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial

    Article • The Lancet Neurology, July 2019, Elsevier

    Professor Malcolm R Macleod, Frank Sullivan, Dr William D Strain, Alison McLoughlin

  5. Extending thrombolysis to 4·5–9 h and wake-up stroke using perfusion imaging: a systematic review and meta-analysis of individual patient data

    Article • The Lancet, July 2019, Elsevier

    Professor Malcolm R Macleod

  6. A randomised controlled trial of an Intervention to Improve Compliance with the ARRIVE guidelines (IICARus)

    Article • Research Integrity and Peer Review, June 2019, Springer Science + Business Media

    Professor Malcolm R Macleod

  7. Outcome heterogeneity and bias in acute experimental spinal cord injury

    Article • Neurology, June 2019, Wolters Kluwer Health

    Professor Malcolm R Macleod

  8. Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial

    Article • The Lancet, June 2019, Elsevier

    Professor Malcolm R Macleod, Frank Sullivan, Dr William D Strain, Alison McLoughlin

  9. Animal models of chemotherapy-induced peripheral neuropathy: A machine-assisted systematic review and meta-analysis

    Article • PLoS Biology, May 2019, PLOS

    Professor Malcolm R Macleod

  10. Thrombolysis Guided by Perfusion Imaging up to 9 Hours after Onset of Stroke

    Article • New England Journal of Medicine, May 2019, New England Journal of Medicine (NEJM/MMS)

    Professor Malcolm R Macleod

  11. Administration of galacto-oligosaccharide prebiotics in the Flinders Sensitive Line animal model of depression

    Article • BMJ Open Science, May 2019, BMJ

    Professor Malcolm R Macleod

  12. Protocol for a systematic review and meta-analysis of data from preclinical studies employing forced swimming test: an update

    Article • BMJ Open Science, May 2019, BMJ

    Professor Malcolm R Macleod

  13. Towards minimum reporting standards for life scientists

    Article • April 2019, Center for Open Science

    Professor Malcolm R Macleod

  14. Therapeutic hypothermia for acute ischaemic stroke. Results of a European multicentre, randomised, phase III clinical trial

    Article • European Stroke Journal, April 2019, SAGE Publications

    Professor Malcolm R Macleod

  15. A European initiative to unclog pipeline for new medicines

    Article • Nature, April 2019, Springer Science + Business Media

    Professor Malcolm R Macleod

  16. The development and evaluation of an online application to assist in the extraction of data from graphs for use in systematic reviews

    Article • Wellcome Open Research, March 2019, Faculty of 1000, Ltd.

    Professor Malcolm R Macleod

  17. The development and evaluation of an online application to assist in the extraction of data from graphs for use in systematic reviews

    Article • Wellcome Open Research, January 2019, Faculty of 1000, Ltd.

    Professor Malcolm R Macleod

  18. Machine learning algorithms for systematic review: reducing workload in a preclinical review of animal studies and reducing human screening error

    Article • Systematic Reviews, January 2019, Springer Science + Business Media

    Professor Malcolm R Macleod

  19. Identifying stroke therapeutics from preclinical models: A protocol for a novel application of network meta-analysis

    Article • F1000Research, January 2019, Faculty of 1000, Ltd.

    Manoj Lalu, Dale Corbett, Professor Malcolm R Macleod, Annette O'Connor, Fatima Haggar

  20. Effects of fluoxetine on functional outcomes after acute stroke (FOCUS): a pragmatic, double-blind, randomised, controlled trial

    Article • The Lancet, January 2019, Elsevier

    Associate Professor Erik Lundström, Professor Malcolm R Macleod, Frank Sullivan, Dr William D Strain, Alison McLoughlin

  21. The development and evaluation of an online application to assist in the extraction of data from graphs for use in systematic reviews

    Article • Wellcome Open Research, December 2018, Faculty of 1000, Ltd.

    Professor Malcolm R Macleod

  22. Potentially serious incidental findings on brain and body magnetic resonance imaging of apparently asymptomatic adults: systematic review and meta-analysis

    Article • BMJ, November 2018, BMJ

    Professor Malcolm R Macleod

  23. Protocol for a systematic review of guidelines for rigour in the design, conduct and analysis of biomedical experiments involving laboratory animals

    Article • BMJ Open Science, September 2018, BMJ

    Professor Malcolm R Macleod

  24. The reproducibility opportunity

    Article • Nature Human Behaviour, August 2018, Springer Science + Business Media

    Professor Malcolm R Macleod

  25. NXY-059, a Failed Stroke Neuroprotectant, Offers No Protection to Stem Cell-Derived Human Neurons

    Article • Journal of Stroke and Cerebrovascular Diseases, August 2018, Elsevier

    Professor Malcolm R Macleod

  26. A randomised controlled trial of an Intervention to Improve Compliance with the ARRIVE guidelines (IICARus)

    Article • July 2018, Cold Spring Harbor Laboratory Press

    Professor Malcolm R Macleod

  27. PRECIOUS: PREvention of Complications to Improve OUtcome in elderly patients with acute Stroke. Rationale and design of a randomised, open, phase III, clinical trial with blinded outcome assessment

    Article • European Stroke Journal, April 2018, SAGE Publications

    Professor Malcolm R Macleod

  28. Small vessels, dementia and chronic diseases – molecular mechanisms and pathophysiology

    Article • Clinical Science, April 2018, Portland Press Ltd.

    Professor Malcolm R Macleod, Dr Atticus H Hainsworth

  29. Effect size and statistical power in the rodent fear conditioning literature – A systematic review

    Article • PLoS ONE, April 2018, PLOS

    Professor Malcolm R Macleod

  30. The use of text-mining and machine learning algorithms in systematic reviews: reducing workload in preclinical biomedical sciences and reducing human screening error

    Article • January 2018, Cold Spring Harbor Laboratory Press

    Professor Malcolm R Macleod

  31. A systematic review and meta-analysis of topoisomerase inhibition in pre-clinical glioma models

    Article • Oncotarget, January 2018, Impact Journals, LLC

    Professor Malcolm R Macleod

  32. Facilitating healthcare decisions by assessing the certainty in the evidence from preclinical animal studies

    Article • PLoS ONE, January 2018, PLOS

    Professor Malcolm R Macleod

  33. Learning lessons from MVA85A, a failed booster vaccine for BCG

    Article • BMJ, January 2018, BMJ

    Professor Malcolm R Macleod

  34. Transparency in the reporting of in vivo pre-clinical pain research: The relevance and implications of the ARRIVE (Animal Research: Reporting In Vivo Experiments) guidelines

    Article • Scandinavian Journal of Pain, December 2017, De Gruyter

    Rosemary Morland, Professor Malcolm R Macleod

  35. Statistical analysis plan for the EuroHYP-1 trial: European multicentre, randomised, phase III clinical trial of the therapeutic hypothermia plus best medical treatment versus best medical treatment alone for acute ischaemic stroke

    Article • Trials, November 2017, Springer Science + Business Media

    Professor Malcolm R Macleod

  36. Identification and characterization of outcome measures reported in animal models of epilepsy: Protocol for a systematic review of the literature-A TASK2 report of the AES/ILAE Translational Task Force of the ILAE

    Article • Epilepsia, November 2017, Wiley

    Professor Malcolm R Macleod

  37. Living systematic reviews: 2. Combining human and machine effort

    Article • Journal of Clinical Epidemiology, November 2017, Elsevier

    Dr Arwel W Jones, Professor Luke Wolfenden, Professor Malcolm R Macleod

  38. Living systematic reviews: 3. Statistical methods for updating meta-analyses

    Article • Journal of Clinical Epidemiology, November 2017, Elsevier

    Dr Arwel W Jones, Professor Luke Wolfenden, Professor Malcolm R Macleod

  39. Living systematic reviews: 4. Living guideline recommendations

    Article • Journal of Clinical Epidemiology, November 2017, Elsevier

    Dr Arwel W Jones, Professor Luke Wolfenden, Professor Malcolm R Macleod

  40. Risk of bias reporting in the recent animal focal cerebral ischaemia literature

    Article • Clinical Science, October 2017, Portland Press Ltd.

    Professor Malcolm R Macleod

  41. Marine-derived n-3 fatty acids therapy for stroke

    Article • Cochrane Database of Systematic Reviews, October 2017, Wiley

    Professor Malcolm R Macleod

  42. The Experimental Design Assistant

    Article • Nature Methods, September 2017, Nature

    Professor Malcolm R Macleod

  43. The Experimental Design Assistant

    Article • PLoS Biology, September 2017, PLOS

    Professor Malcolm R Macleod

  44. Findings of a retrospective, controlled cohort study of the impact of a change in Nature journals' editorial policy for life sciences research on the completeness of reporting study design and execution

    Article • September 2017, Cold Spring Harbor Laboratory Press

    Professor Malcolm R Macleod

  45. Standardized mean differences cause funnel plot distortion in publication bias assessments

    Article • eLife, September 2017, eLife

    Professor Malcolm R Macleod

  46. Living systematic review: 1. Introduction—the why, what, when, and how

    Article • Journal of Clinical Epidemiology, September 2017, Elsevier

    Mr John Hilton, Dr Arwel W Jones, Professor Luke Wolfenden, Professor Malcolm R Macleod

  47. D-galactose-induced brain ageing model: A systematic review and meta-analysis on cognitive outcomes and oxidative stress indices

    Article • PLoS ONE, August 2017, PLOS

    Dr Saeed Sadigh-Eteghad, Professor Malcolm R Macleod

  48. Development of a psychological intervention for fatigue after stroke

    Article • PLoS ONE, August 2017, PLOS

    Professor Malcolm R Macleod

  49. The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments)

    Article • Journal of Cerebral Blood Flow & Metabolism, August 2017, SAGE Publications

    Professor Malcolm R Macleod

  50. Alpha Calcitonin Gene-Related Peptide Increases Cerebral Vessel Diameter in Animal Models of Subarachnoid Hemorrhage: A Systematic Review and Meta-analysis

    Article • Frontiers in Neurology, July 2017, Frontiers

    Professor Malcolm R Macleod

  51. Increasing value and reducing waste in stroke research

    Article • The Lancet Neurology, May 2017, Elsevier

    Professor Malcolm R Macleod

  52. Conjugal amyotrophic lateral sclerosis: a case report from Scotland

    Article • BMC Neurology, March 2017, Springer Science + Business Media

    Professor Malcolm R Macleod

  53. Effect size and statistical power in the rodent fear conditioning literature - a systematic review

    Article • March 2017, Cold Spring Harbor Laboratory Press

    Professor Malcolm R Macleod

  54. Evolution of ischemic damage and behavioural deficit over 6 months after MCAo in the rat: Selecting the optimal outcomes and statistical power for multi-centre preclinical trials

    Article • PLoS ONE, February 2017, PLOS

    Professor Malcolm R Macleod

  55. No publication without confirmation

    Article • Nature, February 2017, Springer Science + Business Media

    Professor Malcolm R Macleod

  56. Hypothermia revisited: Impact of ischaemic duration and between experiment variability

    Article • Journal of Cerebral Blood Flow & Metabolism, January 2017, SAGE Publications

    Professor Malcolm R Macleod

  57. Protocol for a systematic review and meta-analysis of experimental models of amyotrophic lateral sclerosis

    Article • Evidence-based Preclinical Medicine, December 2016, Wiley

    Professor Malcolm R Macleod

  58. Understanding in vivo modelling of depression in non-human animals: a systematic review protocol

    Article • Evidence-based Preclinical Medicine, December 2016, Wiley

    Professor Malcolm R Macleod

  59. Protocols for laboratory research

    Article • Evidence-based Preclinical Medicine, December 2016, Wiley

    Professor Malcolm R Macleod

  60. Evaluating mesenchymal stem cell therapy for sepsis with preclinical meta-analyses prior to initiating a first-in-human trial

    Article • eLife, November 2016, eLife

    Professor Malcolm R Macleod

  61. The Devil Is in the Details: Incomplete Reporting in Preclinical Animal Research

    Article • PLoS ONE, November 2016, PLOS

    Professor Malcolm R Macleod

  62. Study protocol - A systematic review and meta-analysis of hypothermia in experimental traumatic brain injury: Why have promising animal studies not been replicated in pragmatic clinical trials?

    Article • Evidence-based Preclinical Medicine, October 2016, Wiley

    Professor Malcolm R Macleod

  63. Multicenter Evaluation of Geometric Accuracy of MRI Protocols Used in Experimental Stroke

    Article • PLoS ONE, September 2016, PLOS

    Professor Malcolm R Macleod

  64. Systematic Review and Meta-Analysis of the Efficacy of Interleukin-1 Receptor Antagonist in Animal Models of Stroke: an Update

    Article • Translational Stroke Research, August 2016, Springer Science + Business Media

    Professor Malcolm R Macleod

  65. The Efficacy of Trastuzumab in Animal Models of Breast Cancer: A Systematic Review and Meta-Analysis

    Article • PLoS ONE, July 2016, PLOS

    Professor Malcolm R Macleod

  66. A proposed framework for the systematic review and integrated assessment (SYRINA) of endocrine disrupting chemicals

    Article • Environmental Health, July 2016, Springer Science + Business Media

    Professor Malcolm R Macleod

  67. Failed trials for central nervous system disorders do not necessarily invalidate preclinical models and drug targets

    Article • Nature Reviews Drug Discovery, June 2016, Nature

    Professor Malcolm R Macleod

  68. Olfactory Ensheathing Cell Transplantation in Experimental Spinal Cord Injury: Effect size and Reporting Bias of 62 Experimental Treatments: A Systematic Review and Meta-Analysis

    Article • PLoS Biology, May 2016, PLOS

    Professor Malcolm R Macleod

  69. SWIFT-Review: a text-mining workbench for systematic review

    Article • Systematic Reviews, May 2016, Springer Science + Business Media

    Professor Malcolm R Macleod

  70. Protocol for a retrospective, controlled cohort study of the impact of a change in Nature journals’ editorial policy for life sciences research on the completeness of reporting study design and execution

    Article • Scientometrics, May 2016, Springer Science + Business Media

    Professor Malcolm R Macleod

  71. Cause of Death and Predictors of All‐Cause Mortality in Anticoagulated Patients With Nonvalvular Atrial Fibrillation: Data From ROCKET AF

    Article • Journal of the American Heart Association, March 2016, Wolters Kluwer Health

    Professor Malcolm R Macleod, Professor Dmitry Zateyshchikov, Professor Yuriy M. Sirenko

  72. Cardiac Stem Cell Treatment in Myocardial InfarctionNovelty and Significance

    Article • Circulation Research, February 2016, Wolters Kluwer Health

    Professor Joost PG Sluijter, Professor Malcolm R Macleod

  73. Corrigendum to ‘Meta-analysis of data from animal studies: A practical guide’

    Article • Journal of Neuroscience Methods, February 2016, Elsevier

    Professor Malcolm R Macleod

  74. How to Avoid Bumping into the Translational Roadblock

    Article • January 2016, Springer Science + Business Media

    Professor Malcolm R Macleod

  75. AVERT 2 (a very early rehabilitation trial, a very effective reproductive trigger): retrospective observational analysis of the number of babies born to trial staff

    Article • BMJ, December 2015, BMJ

    Professor Julie Bernhardt, Professor Malcolm R Macleod, Professor Amanda G Thrift

  76. Effect of alteplase on the CT hyperdense artery sign and outcome after ischemic stroke

    Article • Neurology, December 2015, Wolters Kluwer Health

    Professor Malcolm R Macleod

  77. Correction: Risk of Bias in Reports of In Vivo Research: A Focus for Improvement

    Article • PLoS Biology, November 2015, PLOS

    Professor Malcolm R Macleod

  78. Informatics: Make sense of health data

    Article • Nature, November 2015, Nature

    Professor Malcolm R Macleod

  79. How individual participant data meta-analyses have influenced trial design, conduct, and analysis

    Article • Journal of Clinical Epidemiology, November 2015, Elsevier

    Professor Malcolm R Macleod

  80. Translational failure of anti-inflammatory compounds for myocardial infarction: a meta-analysis of large animal models

    Article • Cardiovascular Research, October 2015, European Society of Cardiology

    Professor Malcolm R Macleod

  81. Risk of Bias in Reports of In Vivo Research: A Focus for Improvement

    Article • PLoS Biology, October 2015, PLOS

    Professor Malcolm R Macleod

  82. The Clots in Legs Or sTockings after Stroke (CLOTS) 3 trial: a randomised controlled trial to determine whether or not intermittent pneumatic compression reduces the risk of post-stroke deep vein thrombosis and to estimate its cost-effectiveness

    Article • Health Technology Assessment, September 2015, National Institute for Health Research

    Professor Malcolm R Macleod

  83. Consent for Brain Tissue Donation after Intracerebral Haemorrhage: A Community-Based Study

    Article • PLoS ONE, August 2015, PLOS

    Professor Malcolm R Macleod

  84. Exploring threats to generalisability in a large international rehabilitation trial (AVERT)

    Article • BMJ Open, August 2015, BMJ

    Professor Malcolm R Macleod, Professor Julie Bernhardt, Professor Amanda G Thrift

  85. Interventions for post-stroke fatigue

    Article • Cochrane Database of Systematic Reviews, July 2015, Wiley

    Professor Malcolm R Macleod

  86. Efficacy and safety of very early mobilisation within 24 h of stroke onset (AVERT): a randomised controlled trial

    Article • The Lancet, July 2015, Elsevier

    Professor Malcolm R Macleod, Professor Julie Bernhardt, Professor Amanda G Thrift

  87. Effect of Endothelin Receptor Antagonists on Clinically Relevant Outcomes after Experimental Subarachnoid Hemorrhage: A Systematic Review and Meta-Analysis

    Article • Journal of Cerebral Blood Flow & Metabolism, July 2015, SAGE Publications

    Professor Malcolm R Macleod

  88. Prof Benchie and Dr Athena-A modern tragedy…

    Article • Evidence-based Preclinical Medicine, June 2015, Wiley

    Professor Malcolm R Macleod

  89. Increasing value and reducing waste in animal models of rheumatological disease

    Article • International Journal of Rheumatic Diseases, June 2015, Wiley

    Professor Malcolm R Macleod

  90. Drug Repurposing: A Systematic Approach to Evaluate Candidate Oral Neuroprotective Interventions for Secondary Progressive Multiple Sclerosis

    Article • PLoS ONE, April 2015, PLOS

    Professor Malcolm R Macleod

  91. Antiplatelet treatment compared with anticoagulation treatment for cervical artery dissection (CADISS): a randomised trial

    Article • The Lancet Neurology, April 2015, Elsevier

    Professor Malcolm R Macleod

  92. Experimental design and reporting standards for improving the internal validity of pre-clinical studies in the field of pain: Consensus of the IMI-Europain consortium

    Article • Scandinavian Journal of Pain, April 2015, De Gruyter

    Professor Malcolm R Macleod

  93. Uptake of systematic reviews and meta-analyses based on individual participant data in clinical practice guidelines: descriptive study

    Article • BMJ, March 2015, BMJ

    Professor Malcolm R Macleod

  94. Magnetic Resonance Imaging in Experimental Stroke and Comparison With Histology

    Article • Stroke, February 2015, Wolters Kluwer Health

    Professor Malcolm R Macleod

  95. Model of Understanding Fatigue After Stroke

    Article • Stroke, February 2015, Wolters Kluwer Health

    Professor Malcolm R Macleod, Trudie Chalder

  96. Influence of Intracerebral Hemorrhage Location on Incidence, Characteristics, and Outcome

    Article • Stroke, February 2015, Wolters Kluwer Health

    Professor Malcolm R Macleod

  97. A systematic review and meta‐analysis of gene therapy in animal models of cerebral glioma: why did promise not translate to human therapy?

    Article • Evidence-based Preclinical Medicine, December 2014, Wiley

    Professor Malcolm R Macleod

  98. Incidence, prevalence, and predictors of chemotherapy-induced peripheral neuropathy: A systematic review and meta-analysis

    Article • Pain, December 2014, Wolters Kluwer Health

    Professor Malcolm R Macleod

  99. Effect of intermittent pneumatic compression on disability, living circumstances, quality of life, and hospital costs after stroke: secondary analyses from CLOTS 3, a randomised trial

    Article • The Lancet Neurology, December 2014, Elsevier

    Professor Malcolm R Macleod

  100. Similar Effect of Autologous and Allogeneic Cell Therapy for Ischemic Heart Disease: Systematic Review and Meta-Analysis of Large Animal Studies

    Article • Circulation Research, September 2014, Wolters Kluwer Health

    Miss Sanne J. Jansen of Lorkeers, Professor Malcolm R Macleod

  101. Efficacy of Antidepressants in Animal Models of Ischemic Stroke: A Systematic Review and Meta-Analysis

    Article • Stroke, September 2014, Wolters Kluwer Health

    Professor Malcolm R Macleod

  102. Preclinical research: Design animal studies better

    Article • Nature, June 2014, Nature

    Professor Malcolm R Macleod

  103. Efficacy and Safety of Rivaroxaban Compared With Warfarin Among Elderly Patients With Nonvalvular Atrial Fibrillation in the Rivaroxaban Once Daily, Oral, Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embol...

    Article • Circulation, June 2014, Wolters Kluwer Health

    Professor Malcolm R Macleod

  104. EuroHYP-1: European Multicenter, Randomized, Phase III Clinical Trial of Therapeutic Hypothermia plus Best Medical Treatment vs. Best Medical Treatment Alone for Acute Ischemic Stroke

    Article • International Journal of Stroke, May 2014, SAGE Publications

    Professor Malcolm R Macleod

  105. End-of-life decisions in patients with severe acute brain injury

    Article • The Lancet Neurology, May 2014, Elsevier

    Professor Malcolm R Macleod

  106. Psychological Associations of Poststroke Fatigue: A Systematic Review and Meta-Analysis

    Article • Stroke, April 2014, Wolters Kluwer Health

    Professor Malcolm R Macleod

  107. Using Animal Models to Understand Cancer Pain in Humans

    Article • Current Pain and Headache Reports, April 2014, Springer Science + Business Media

    Professor Malcolm R Macleod

  108. Outcome After Conservative Management or Intervention for Unruptured Brain Arteriovenous Malformations

    Article • JAMA, April 2014, American Medical Association (AMA)

    Professor Malcolm R Macleod

  109. Clopidogrel Plus Aspirin Versus Warfarin in Patients With Stroke and Aortic Arch Plaques

    Article • Stroke, April 2014, Wolters Kluwer Health

    Professor Malcolm R Macleod

  110. Research: increasing value, reducing waste – Authors' reply

    Article • The Lancet, March 2014, Elsevier

    Professor Malcolm R Macleod

  111. Systematic Reviews and Meta-Analysis of Preclinical Studies: Why Perform Them and How to Appraise Them Critically

    Article • Journal of Cerebral Blood Flow & Metabolism, February 2014, SAGE Publications

    Professor Malcolm R Macleod

  112. Exercise Reduces Infarct Volume and Facilitates Neurobehavioral Recovery

    Article • Neurorehabilitation and Neural Repair, February 2014, SAGE Publications

    Professor Malcolm R Macleod, Professor Julie Bernhardt

  113. Therapeutic Hypothermia and the Risk of Infection

    Article • Critical Care Medicine, February 2014, Wolters Kluwer Health

    Professor Malcolm R Macleod

  114. A (mini) pill for stroke?

    Article • Brain, February 2014, Oxford University Press (OUP)

    Professor Malcolm R Macleod

  115. Some Salt with Your Statin, Professor?

    Article • PLoS Biology, January 2014, PLOS

    Professor Malcolm R Macleod

  116. Hypothermia Protects Human Neurons

    Article • International Journal of Stroke, January 2014, SAGE Publications

    Professor Malcolm R Macleod

  117. Systematic Review and Meta-Analysis of Interventions Tested in Animal Models of Lacunar Stroke

    Article • Stroke, January 2014, Wolters Kluwer Health

    Professor Malcolm R Macleod

  118. Meta-analysis of data from animal studies: A practical guide

    Article • Journal of Neuroscience Methods, January 2014, Elsevier

    Professor Malcolm R Macleod

  119. Increasing value and reducing waste in research design, conduct, and analysis

    Article • The Lancet, January 2014, Elsevier

    Professor Malcolm R Macleod

  120. Increasing value and reducing waste in biomedical research regulation and management

    Article • The Lancet, January 2014, Elsevier

    Professor Malcolm R Macleod

  121. Effect and Reporting Bias of RhoA/ROCK-Blockade Intervention on Locomotor Recovery After Spinal Cord Injury

    Article • JAMA Neurology, January 2014, American Medical Association (AMA)

    Professor Malcolm R Macleod

  122. Biomedical research: increasing value, reducing waste

    Article • The Lancet, January 2014, Elsevier

    Professor Malcolm R Macleod

  123. Efficacy and safety of mesenchymal stromal cells in preclinical models of acute lung injury: a systematic review protocol

    Article • Systematic Reviews, January 2014, Springer Science + Business Media

    Professor Malcolm R Macleod

  124. Stem Cell Transplantation in Traumatic Spinal Cord Injury: A Systematic Review and Meta-Analysis of Animal Studies

    Article • PLoS Biology, December 2013, PLOS

    Professor Malcolm R Macleod

  125. Edoxaban versus Warfarin in Patients with Atrial Fibrillation

    Article • New England Journal of Medicine, November 2013, New England Journal of Medicine (NEJM/MMS)

    Professor Malcolm R Macleod, Prof. Elisabeta Badila, Director of the stroke unit, DMSci, clinical research associate professor Helle K. Iversen, Professor Dmitry Zateyshchikov, Professor Yuriy M. Sirenko

  126. Bringing rigour to translational medicine

    Article • Nature Reviews Neurology, November 2013, Springer Science + Business Media

    Professor Malcolm R Macleod

  127. Edaravone Improves Functional and Structural Outcomes in Animal Models of Focal Cerebral Ischemia: A Systematic Review

    Article • International Journal of Stroke, October 2013, SAGE Publications

    Professor Malcolm R Macleod

  128. Meta-Analysis of Pre-Clinical Studies of Early Decompression in Acute Spinal Cord Injury: A Battle of Time and Pressure

    Article • PLoS ONE, August 2013, PLOS

    Professor Malcolm R Macleod

  129. Systematic Review and Meta-Analysis of Therapeutic Hypothermia in Animal Models of Spinal Cord Injury

    Article • PLoS ONE, August 2013, PLOS

    Professor Malcolm R Macleod

  130. Effectiveness of intermittent pneumatic compression in reduction of risk of deep vein thrombosis in patients who have had a stroke (CLOTS 3): a multicentre randomised controlled trial

    Article • The Lancet, August 2013, Elsevier

    Professor Malcolm R Macleod

  131. Evaluation of Excess Significance Bias in Animal Studies of Neurological Diseases

    Article • PLoS Biology, July 2013, PLOS

    Professor Malcolm R Macleod

  132. Hypertension and Experimental Stroke Therapies

    Article • Journal of Cerebral Blood Flow & Metabolism, June 2013, SAGE Publications

    Professor Malcolm R Macleod

  133. Animal models of bone cancer pain: Systematic review and meta-analyses

    Article • Pain, June 2013, Wolters Kluwer Health

    Professor Malcolm R Macleod

  134. Systematic review and stratified meta-analysis of the efficacy of RhoA and Rho kinase inhibitors in animal models of ischaemic stroke

    Article • Systematic Reviews, May 2013, Springer Science + Business Media

    Professor Malcolm R Macleod

  135. Prevalence and natural history of pain in adults with multiple sclerosis: Systematic review and meta-analysis

    Article • Pain, May 2013, Wolters Kluwer Health

    Professor Malcolm R Macleod

  136. A Concerted Appeal for International Cooperation in Preclinical Stroke Research

    Article • Stroke, April 2013, Wolters Kluwer Health

    Professor Malcolm R Macleod

  137. Evidence-based Translational Medicine

    Article • Stroke, April 2013, Wolters Kluwer Health

    Professor Malcolm R Macleod

  138. Systematic review and meta-analysis of temozolomide in animal models of glioma: was clinical efficacy predicted?

    Article • British Journal of Cancer, January 2013, Springer Science + Business Media

    Professor Malcolm R Macleod

  139. Role of multidetector computed tomography in the diagnosis and management of patients attending the rapid access chest pain clinic, The Scottish computed tomography of the heart (SCOT-HEART) trial: study protocol for randomized controlled trial

    Article • Trials, October 2012, Springer Science + Business Media

    Professor Malcolm R Macleod

  140. A call for transparent reporting to optimize the predictive value of preclinical research

    Article • Nature, October 2012, Springer Science + Business Media

    Professor Malcolm R Macleod

  141. Vorapaxar for secondary prevention of thrombotic events for patients with previous myocardial infarction: a prespecified subgroup analysis of the TRA 2°P-TIMI 50 trial

    Article • The Lancet, October 2012, Elsevier

    Professor Malcolm R Macleod

  142. The Benefit of Hypothermia in Experimental Ischemic Stroke is Not Affected by Pethidine

    Article • International Journal of Stroke, July 2012, SAGE Publications

    Professor Malcolm R Macleod

  143. Improving the Efficiency of the Development of Drugs for Stroke

    Article • International Journal of Stroke, June 2012, SAGE Publications

    Professor Malcolm R Macleod

  144. Translational Research

    Article • International Journal of Stroke, June 2012, SAGE Publications

    Professor Malcolm R Macleod

  145. Stem Cell-Based Therapy for Experimental Stroke: A Systematic Review and Meta-Analysis

    Article • International Journal of Stroke, June 2012, SAGE Publications

    Professor Malcolm R Macleod

  146. Voltage-gated potassium channel antibody-related encephalopathy: a case which may extend the documented phenotype of this condition

    Article • BMJ Case Reports, June 2012, BMJ

    Professor Malcolm R Macleod

  147. The benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the third international stroke trial [IST-3]): a randomised controlled trial

    Article • The Lancet, June 2012, Elsevier

    Professor Malcolm R Macleod, Dr William D Strain

  148. Antiplatelet therapy and the effects of B vitamins in patients with previous stroke or transient ischaemic attack: a post-hoc subanalysis of VITATOPS, a randomised, placebo-controlled trial

    Article • The Lancet Neurology, June 2012, Elsevier

    Professor Malcolm R Macleod, Prof. J. David Spence

  149. Pharmacologic Reduction of Angiographic Vasospasm in Experimental Subarachnoid Hemorrhage: Systematic Review and Meta-Analysis

    Article • Journal of Cerebral Blood Flow & Metabolism, April 2012, SAGE Publications

    Professor Malcolm R Macleod

  150. Vorapaxar in the Secondary Prevention of Atherothrombotic Events

    Article • New England Journal of Medicine, April 2012, New England Journal of Medicine (NEJM/MMS)

    Professor Malcolm R Macleod, M.D Ph.D Serge Timsit, Director of the stroke unit, DMSci, clinical research associate professor Helle K. Iversen

  151. Rivaroxaban compared with warfarin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a subgroup analysis of ROCKET AF

    Article • The Lancet Neurology, April 2012, Elsevier

    Professor Malcolm R Macleod

  152. Untreated clinical course of cerebral cavernous malformations: a prospective, population-based cohort study

    Article • The Lancet Neurology, March 2012, Elsevier

    Professor Malcolm R Macleod

  153. Evaluation of Combination Therapy in Animal Models of Cerebral Ischemia

    Article • Journal of Cerebral Blood Flow & Metabolism, February 2012, SAGE Publications

    Professor Malcolm R Macleod

  154. Update on the third international stroke trial (IST-3) of thrombolysis for acute ischaemic stroke and baseline features of the 3035 patients recruited

    Article • Trials, November 2011, Springer Science + Business Media

    Professor Malcolm R Macleod, Associate Professor Erik Lundström

  155. The timing, extent, progression and regression of deep vein thrombosis in immobile stroke patients: observational data from the CLOTS multicenter randomized trials

    Article • Journal of Thrombosis and Haemostasis, November 2011, Wiley

    Professor Malcolm R Macleod

  156. Preclinical studies of human disease: Time to take methodological quality seriously

    Article • Journal of Molecular and Cellular Cardiology, October 2011, Elsevier

    Professor Malcolm R Macleod

  157. Rivaroxaban versus Warfarin in Nonvalvular Atrial Fibrillation

    Article • New England Journal of Medicine, September 2011, New England Journal of Medicine (NEJM/MMS)

    Professor Malcolm R Macleod

  158. Why animal research needs to improve

    Article • Nature, September 2011, Springer Science + Business Media

    Professor Malcolm R Macleod

  159. Sodium and chloride channelopathies with myositis: Coincidence or connection?

    Article • Muscle & Nerve, June 2011, Wiley

    Professor Malcolm R Macleod

  160. Terutroban versus aspirin in patients with cerebral ischaemic events (PERFORM): a randomised, double-blind, parallel-group trial

    Article • The Lancet, June 2011, Elsevier

    Professor Malcolm R Macleod, Prof. Dr. Otto W. Witte, Professor Ivan G. Milanov

  161. Dopamine agonists in animal models of Parkinson’s disease: A systematic review and meta-analysis

    Article • Parkinsonism & Related Disorders, June 2011, Elsevier

    Professor Malcolm R Macleod

  162. Not Tonight, Darling, I Might Get a Headache

    Article • Stroke, May 2011, Wolters Kluwer Health

    Professor Malcolm R Macleod

  163. Systematic Survey of the Design, Statistical Analysis, and Reporting of Studies Published in the 2008 Volume of the Journal of Cerebral Blood Flow and Metabolism

    Article • Journal of Cerebral Blood Flow & Metabolism, April 2011, SAGE Publications

    Professor Malcolm R Macleod

  164. Treatment of intracerebral hemorrhage in animal models: Meta-analysis

    Article • Annals of Neurology, February 2011, Wiley

    Professor Malcolm R Macleod

  165. Systematic Survey of the Design, Statistical Analysis, and Reporting of Studies Published in the 2008 Volume of theJournal of Cerebral Blood Flow and Metabolism

    Article • Journal of Cerebral Blood Flow & Metabolism, December 2010, SAGE Publications

    Professor Malcolm R Macleod

  166. Animal models of neurological disease: are there any babies in the bathwater?

    Article • Practical Neurology, November 2010, BMJ

    Professor Malcolm R Macleod

  167. Hypothermia for Stroke: Call to Action 2010

    Article • International Journal of Stroke, November 2010, SAGE Publications

    Professor Malcolm R Macleod

  168. Preclinical Drug Evaluation for Combination Therapy in Acute Stroke Using Systematic Review, Meta-Analysis, and Subsequent Experimental Testing

    Article • Journal of Cerebral Blood Flow & Metabolism, October 2010, SAGE Publications

    Professor Malcolm R Macleod

  169. B vitamins in patients with recent transient ischaemic attack or stroke in the VITAmins TO Prevent Stroke (VITATOPS) trial: a randomised, double-blind, parallel, placebo-controlled trial

    Article • The Lancet Neurology, September 2010, Elsevier

    Professor Malcolm R Macleod, Prof. J. David Spence

  170. Improving the translational hit of experimental treatments in multiple sclerosis

    Article • Multiple Sclerosis Journal, August 2010, SAGE Publications

    Professor Malcolm R Macleod

  171. Factors Affecting the Apparent Efficacy and Safety of Tissue Plasminogen Activator in Thrombotic Occlusion Models of Stroke: Systematic Review and Meta-Analysis

    Article • Journal of Cerebral Blood Flow & Metabolism, July 2010, SAGE Publications

    Professor Malcolm R Macleod

  172. Different Strokes for Different Folks: The Rich Diversity of Animal Models of Focal Cerebral Ischemia

    Article • Journal of Cerebral Blood Flow & Metabolism, May 2010, SAGE Publications

    Professor Malcolm R Macleod

  173. Comment on "Detection of an Infectious Retrovirus, XMRV, in Blood Cells of Patients with Chronic Fatigue Syndrome"

    Article • Science, May 2010, American Association for the Advancement of Science

    Professor Malcolm R Macleod

  174. Therapeutic Hypothermia for Acute Ischemic Stroke: Ready to Start Large Randomized Trials?

    Article • Journal of Cerebral Blood Flow & Metabolism, March 2010, SAGE Publications

    Professor Malcolm R Macleod

  175. Publication Bias in Reports of Animal Stroke Studies Leads to Major Overstatement of Efficacy

    Article • PLoS Biology, March 2010, PLOS

    Professor Malcolm R Macleod

  176. Can Animal Models of Disease Reliably Inform Human Studies?

    Article • PLoS Medicine, March 2010, PLOS

    Professor Malcolm R Macleod

  177. How to Avoid Bumping into the Translational Roadblock

    Article • January 2010, Springer Science + Business Media

    Professor Malcolm R Macleod

  178. A Systematic Review and Meta-Analysis of Erythropoietin in Experimental Stroke

    Article • Journal of Cerebral Blood Flow & Metabolism, December 2009, SAGE Publications

    Professor Malcolm R Macleod

  179. Emulating Multicentre Clinical Stroke Trials: A New Paradigm for Studying Novel Interventions in Experimental Models of Stroke

    Article • International Journal of Stroke, December 2009, SAGE Publications

    Professor Malcolm R Macleod

  180. Bacterial meningitis associated with a complex ischiorectal abscess

    Article • Journal of Clinical Neuroscience, December 2009, Elsevier

    Professor Malcolm R Macleod

  181. Stroke research at a road block: the streets from adversity should be paved with meta-analysis and good laboratory practice

    Article • British Journal of Pharmacology, August 2009, Wiley

    Professor Malcolm R Macleod

  182. Systematic Review and Stratified Meta-analysis of the Efficacy of Interleukin-1 Receptor Antagonist in Animal Models of Stroke

    Article • Journal of Stroke and Cerebrovascular Diseases, July 2009, Elsevier

    Professor Malcolm R Macleod

  183. Scope of Preclinical Testing Versus Quality Control Within Experiments

    Article • Stroke, June 2009, Wolters Kluwer Health

    Professor Malcolm R Macleod

  184. Injury-induced mineralocorticoid receptor expression involves differential promoter usage: A novel role for the rat MRβ variant

    Article • Molecular and Cellular Endocrinology, June 2009, Elsevier

    Professor Malcolm R Macleod

  185. Effectiveness of thigh-length graduated compression stockings to reduce the risk of deep vein thrombosis after stroke (CLOTS trial 1): a multicentre, randomised controlled trial

    Article • The Lancet, June 2009, Elsevier

    Professor Malcolm R Macleod

  186. Reprint: Good Laboratory Practice: Preventing Introduction of Bias at the Bench

    Article • Journal of Cerebral Blood Flow & Metabolism, June 2009, SAGE Publications

    Professor Malcolm R Macleod

  187. Stroke Therapy Academic Industry Roundtable (STAIR) Recommendations for Extended Window Acute Stroke Therapy Trials

    Article • Stroke, May 2009, Wolters Kluwer Health

    Professor Malcolm R Macleod

  188. Surgical decompression for space-occupying cerebral infarction (the Hemicraniectomy After Middle Cerebral Artery infarction with Life-threatening Edema Trial [HAMLET]): a multicentre, open, randomised trial

    Article • The Lancet Neurology, April 2009, Elsevier

    Professor Malcolm R Macleod

  189. Mineralocorticoid receptor mRNA expression is increased in human hippocampus following brief cerebral ischaemia

    Article • Neuropathology and Applied Neurobiology, April 2009, Wiley

    Professor Malcolm R Macleod

  190. Update of the Stroke Therapy Academic Industry Roundtable Preclinical Recommendations

    Article • Stroke, February 2009, Wolters Kluwer Health

    Professor Malcolm R Macleod

  191. REPRINT: Good Laboratory Practice: Preventing Introduction of Bias at the Bench

    Article • International Journal of Stroke, February 2009, SAGE Publications

    Professor Malcolm R Macleod

  192. Effect of hyperthermia and anoxia on glucocorticoid and mineralocorticoid receptor expression in neonatal rat hippocampus

    Article • Neuroscience Letters, January 2009, Elsevier

    Professor Malcolm R Macleod

  193. Rationale and Design of a Randomized, Double-Blind, Parallel-Group Study of Terutroban 30 mg/day versus Aspirin 100 mg/day in Stroke Patients: The Prevention of Cerebrovascular and Cardiovascular Events of Ischemic Origin with Terutroban in Patients wi...

    Article • Cerebrovascular Diseases, January 2009, Karger Publishers

    Professor Malcolm R Macleod, Prof. Dr. Otto W. Witte, Professor Ivan G. Milanov

  194. General anaesthesia versus local anaesthesia for carotid surgery (GALA): a multicentre, randomised controlled trial

    Article • The Lancet, December 2008, Elsevier

    Professor Malcolm R Macleod, Alba Piroli, Professor David Torgerson, Dr. Ron Milo

  195. The Future of Restorative Neurosciences in Stroke: Driving the Translational Research Pipeline From Basic Science to Rehabilitation of People After Stroke

    Article • Neurorehabilitation and Neural Repair, November 2008, SAGE Publications

    Professor Malcolm R Macleod

  196. What is the translational efficacy of chemotherapeutic drug research in neuro-oncology? A systematic review and meta-analysis of the efficacy of BCNU and CCNU in animal models of glioma

    Article • Journal of Neuro-Oncology, September 2008, Springer Science + Business Media

    Professor Malcolm R Macleod

  197. Reprint: Good Laboratory Practice: Preventing Introduction of Bias at the Bench

    Article • Journal of Cerebral Blood Flow & Metabolism, September 2008, SAGE Publications

    Professor Malcolm R Macleod

  198. Secondary prevention of stroke – Authors' reply

    Article • The Lancet, September 2008, Elsevier

    Professor Malcolm R Macleod

  199. Good Laboratory Practice: Preventing Introduction of Bias at the Bench

    Article • Stroke, August 2008, Wolters Kluwer Health

    Professor Malcolm R Macleod

  200. Evidence for the Efficacy of NXY-059 in Experimental Focal Cerebral Ischaemia Is Confounded by Study Quality

    Article • Stroke, July 2008, Wolters Kluwer Health

    Professor Malcolm R Macleod

  201. Stroke

    Article • The Lancet, May 2008, Elsevier

    Professor Malcolm R Macleod

  202. Predicting outcome in hyper-acute stroke: validation of a prognostic model in the Third International Stroke Trial (IST3)

    Article • Journal of Neurology Neurosurgery & Psychiatry, April 2008, BMJ

    Professor Malcolm R Macleod

  203. Outcome after interventional or conservative management of unruptured brain arteriovenous malformations: a prospective, population-based cohort study

    Article • The Lancet Neurology, March 2008, Elsevier

    Professor Malcolm R Macleod

  204. Empirical Evidence of Bias in the Design of Experimental Stroke Studies: A Metaepidemiologic Approach

    Article • Stroke, January 2008, Wolters Kluwer Health

    Professor Malcolm R Macleod

  205. A Systematic Review and Meta-Analysis of the Efficacy of Piracetam and Piracetam-Like Compounds in Experimental Stroke

    Article • Cerebrovascular Diseases, November 2007, Karger Publishers

    Professor Malcolm R Macleod

  206. How can we improve the pre-clinical development of drugs for stroke?

    Article • Trends in Neurosciences, September 2007, Elsevier

    Professor Malcolm R Macleod

  207. Vanishing diplopia: a problem case

    Article • Practical Neurology, August 2007, BMJ

    Professor Malcolm R Macleod

  208. Hypothermia in animal models of acute ischaemic stroke: a systematic review and meta-analysis

    Article • Brain, May 2007, Oxford University Press (OUP)

    Professor Malcolm R Macleod

  209. Forebrain mineralocorticoid receptor overexpression enhances memory, reduces anxiety and attenuates neuronal loss in cerebral ischaemia

    Article • European Journal of Neuroscience, April 2007, Wiley

    Professor Malcolm R Macleod

  210. Systematic Review and Meta-Analysis of the Efficacy of Tirilazad in Experimental Stroke

    Article • Stroke, January 2007, Wolters Kluwer Health

    Professor Malcolm R Macleod

  211. Comparison of treatment effects between animal experiments and clinical trials: systematic review

    Article • BMJ, December 2006, BMJ

    Professor Malcolm R Macleod

  212. Hemicraniectomy after middle cerebral artery infarction with life-threatening Edema trial (HAMLET). Protocol for a randomised controlled trial of decompressive surgery in space-occupying hemispheric infarction

    Article • Trials, September 2006, Springer Science + Business Media

    Professor Malcolm R Macleod

  213. Aortic Arch Atheroma

    Article • International Journal of Stroke, May 2006, SAGE Publications

    Professor Malcolm R Macleod

  214. 1,026 Experimental treatments in acute stroke

    Article • Annals of Neurology, March 2006, Wiley

    Professor Malcolm R Macleod

  215. Greater Incidence of Both Fatal and Nonfatal Strokes in Disadvantaged Areas: The Northeast Melbourne Stroke Incidence Study

    Article • Stroke, January 2006, Wolters Kluwer Health

    Professor Malcolm R Macleod, Professor Amanda G Thrift

  216. Current Issues in the Treatment of Acute Posterior Circulation Stroke

    Article • CNS Drugs, January 2006, Springer Science + Business Media

    Professor Malcolm R Macleod

  217. Epilepsy update

    Article • The Lancet Neurology, October 2005, Elsevier

    Professor Malcolm R Macleod

  218. Surveying the literature from animal experiments: Systematic review and meta-analysis are important contributions

    Article • BMJ, July 2005, BMJ

    Professor Malcolm R Macleod

  219. Neuro-oncology for non-oncologists

    Article • The Lancet Neurology, June 2005, Elsevier

    Professor Malcolm R Macleod

  220. Overexpression of the mineralocorticoid receptor protects against injury in PC12 cells

    Article • Molecular Brain Research, April 2005, Elsevier

    Professor Malcolm R Macleod

  221. Systematic Review and Metaanalysis of the Efficacy of FK506 in Experimental Stroke

    Article • Journal of Cerebral Blood Flow & Metabolism, February 2005, SAGE Publications

    Professor Malcolm R Macleod

  222. Gender and deprivation and rates of referral and thereby admission to a national neurorehabilitation service

    Article • Clinical Rehabilitation, February 2005, SAGE Publications

    Professor Malcolm R Macleod

  223. Systematic review and meta-analysis of the efficacy of melatonin in experimental stroke

    Article • Journal of Pineal Research, January 2005, Wiley

    Professor Malcolm R Macleod

  224. Results of a Multicentre, Randomised Controlled Trial of Intra-Arterial Urokinase in the Treatment of Acute Posterior Circulation Ischaemic Stroke

    Article • Cerebrovascular Diseases, January 2005, Karger Publishers

    Professor Malcolm R Macleod

  225. MicroRNA – Taking Regulation of Protein Synthesis to Another Level

    Article • Cerebrovascular Diseases, January 2005, Karger Publishers

    Professor Malcolm R Macleod

  226. Nicotinamide Attenuates Focal Ischemic Brain Injury: Meta-Analysis or Mechanism of Protection

    Article • Stroke, December 2004, Wolters Kluwer Health

    Professor Malcolm R Macleod

  227. Atheroma of the aortic arch: an important and poorly recognised factor in the aetiology of stroke

    Article • The Lancet Neurology, July 2004, Elsevier

    Professor Malcolm R Macleod

  228. Pooling of Animal Experimental Data Reveals Influence of Study Design and Publication Bias

    Article • Stroke, April 2004, Wolters Kluwer Health

    Professor Malcolm R Macleod

  229. Media Watch

    Article • The Lancet Neurology, December 2003, Elsevier

    Professor Malcolm R Macleod

  230. Atheroma of the aortic arch: the missing link in the secondary prevention of stroke?

    Article • Expert Review of Cardiovascular Therapy, November 2003, Taylor & Francis

    Professor Malcolm R Macleod

  231. Inequalities in the incidence and management of, and outcome from, neurological diseases in older people

    Article • Reviews in Clinical Gerontology, August 2003, Cambridge University Press

    Professor Malcolm R Macleod

  232. Mineralocorticoid receptor expression and increased survival following neuronal injury

    Article • European Journal of Neuroscience, April 2003, Wiley

    Professor Malcolm R Macleod

  233. Effect of deprivation on time to hospital in acute stroke

    Article • Journal of Neurology Neurosurgery & Psychiatry, April 2003, BMJ

    Professor Malcolm R Macleod

  234. Reduced NMDA-induced apoptosis in neurons lacking ataxia telangiectasia mutated protein

    Article • Neuroreport, February 2003, Wolters Kluwer Health

    Professor Malcolm R Macleod

  235. PubMed: http://www.pubmed.org

    Article • Journal of Neurology Neurosurgery & Psychiatry, December 2002, BMJ

    Professor Malcolm R Macleod

  236. Effect of deprivation and gender on the incidence and management of acute brain disorders

    Article • Intensive Care Medicine, December 2002, Springer Science + Business Media

    Professor Malcolm R Macleod

  237. What's a good doctor and how do you make one?

    Article • BMJ, September 2002, BMJ

    Professor Malcolm R Macleod

  238. Nitric-oxide-synthase-mediated cyclic guanosine monophosphate production in neonatal rat cerebellar prisms is resistant to calcineurin inhibition

    Article • Neuroscience Letters, March 2002, Elsevier

    Professor Malcolm R Macleod

  239. Serum withdrawal causes apoptosis in SHSY 5Y cells

    Article • Brain Research, January 2001, Elsevier

    Professor Malcolm R Macleod

  240. Caspase 6 activity initiates caspase 3 activation in cerebellar granule cell apoptosis

    Article • Cell Death and Differentiation, September 2000, Springer Science + Business Media

    Professor Malcolm R Macleod

  241. The effect of tumour associated epilepsy on performance/handicap scales used in cerebral glioma

    Article • British Journal of Neurosurgery, January 1995, Taylor & Francis

    Professor Malcolm R Macleod

  242. Ischaemic heart disease and cholesterol There's more to heart disease than cholesterol

    Article • BMJ, April 1994, BMJ

    Professor Malcolm R Macleod