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  1. Relative Recovery of Non-Alcoholic Fatty Liver Disease (NAFLD) in Diet-Induced Obese Rats

    Article • Nutrients, December 2023, MDPI AG

    Professor of Vascular Physiology Lucie Clapp

  2. The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors

    Article • British Journal of Pharmacology, October 2023, Wiley

    Professor Alistair Mathie, Professor of Vascular Physiology Lucie Clapp

  3. Prostacyclin mimetics inhibit DRP1-mediated pro-proliferative mitochondrial fragmentation in pulmonary arterial hypertension

    Article • Vascular Pharmacology, August 2023, Elsevier

    Professor of Vascular Physiology Lucie Clapp

  4. Prostanoid receptors in GtoPdb v.2023.1

    Article • IUPHAR/BPS Guide to Pharmacology CITE, April 2023, Edinburgh University Library

    Professor of Vascular Physiology Lucie Clapp

  5. OGC P05 Liquid biopsy in oesophageal cancer: a systematic review of blood biomarkers for early diagnosis

    Article • BJS, December 2022, Oxford University Press (OUP)

    Professor of Vascular Physiology Lucie Clapp

  6. Therapeutic potential of inhibiting histone 3 lysine 27 demethylases: a review of the literature

    Article • Clinical Epigenetics, August 2022, Springer Science + Business Media

    Professor of Vascular Physiology Lucie Clapp

  7. SPOD2 Microvesicles as biomarkers for the screening of colorectal neoplasm

    Article • BJS, August 2022, Oxford University Press (OUP)

    Professor of Vascular Physiology Lucie Clapp

  8. The role of microvesicles as biomarkers in the screening of colorectal neoplasm

    Article • Cancer Medicine, March 2022, Wiley

    Professor of Vascular Physiology Lucie Clapp

  9. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein‐coupled receptors

    Article • British Journal of Pharmacology, September 2021, Wiley

    Professor Alistair Mathie, Stephen Alexander, Professor of Vascular Physiology Lucie Clapp

  10. The Prostacyclin Analogue, Treprostinil, Used in the Treatment of Pulmonary Arterial Hypertension, is a Potent Antagonist of TREK-1 and TREK-2 Potassium Channels

    Article • Frontiers in Pharmacology, June 2021, Frontiers

    Professor Alistair Mathie, Professor of Vascular Physiology Lucie Clapp

  11. Prostanoid receptors in GtoPdb v.2021.2

    Article • IUPHAR/BPS Guide to Pharmacology CITE, June 2021, Edinburgh University Library

    Professor of Vascular Physiology Lucie Clapp

  12. Prostanoid receptors (version 2020.4) in the IUPHAR/BPS Guide to Pharmacology Database

    Article • IUPHAR/BPS Guide to Pharmacology CITE, September 2020, Edinburgh University Library

    Professor of Vascular Physiology Lucie Clapp

  13. International Union of Basic and Clinical Pharmacology. CIX. Differences and Similarities between Human and Rodent Prostaglandin E2Receptors (EP1–4) and Prostacyclin Receptor (IP): Specific Roles in Pathophysiologic Conditions

    Article • Pharmacological Reviews, September 2020, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor of Vascular Physiology Lucie Clapp

  14. Interaction between PGI2 and ET-1 pathways in vascular smooth muscle from Group-III pulmonary hypertension patients

    Article • Prostaglandins & Other Lipid Mediators, February 2020, Elsevier

    Professor of Vascular Physiology Lucie Clapp

  15. Diverse Pharmacology of Prostacyclin Mimetics: Implications for Pulmonary Hypertension

    Article • January 2020, Springer Science + Business Media

    Professor of Vascular Physiology Lucie Clapp

  16. Synthetic routes to treprostinil N-acyl methylsulfonamide

    Article • Tetrahedron Letters, January 2020, Elsevier

    Professor of Vascular Physiology Lucie Clapp

  17. Altered cyclooxygenase-1 and enhanced thromboxane receptor activities underlie attenuated endothelial dilatory capacity of omental arteries in obesity

    Article • Life Sciences, December 2019, Elsevier

    Professor of Vascular Physiology Lucie Clapp

  18. Prostanoid receptors (version 2019.5) in the IUPHAR/BPS Guide to Pharmacology Database

    Article • IUPHAR/BPS Guide to Pharmacology CITE, November 2019, Edinburgh University Library

    Professor of Vascular Physiology Lucie Clapp

  19. THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: G protein-coupled receptors

    Article • British Journal of Pharmacology, November 2019, Wiley

    Professor Alistair Mathie, Stephen Alexander, Prof daniel hoyer, Professor of Vascular Physiology Lucie Clapp

  20. Bronchodilation induced by PGE2 is impaired in Group III pulmonary hypertension

    Article • British Journal of Pharmacology, October 2019, Wiley

    Professor of Vascular Physiology Lucie Clapp

  21. Prostanoid receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

    Article • IUPHAR/BPS Guide to Pharmacology CITE, September 2019, Edinburgh University Library

    Professor of Vascular Physiology Lucie Clapp

  22. Exploring the enzymatic degradation of poly(glycerol adipate)

    Article • European Journal of Pharmaceutics and Biopharmaceutics, September 2019, Elsevier

    Professor of Vascular Physiology Lucie Clapp

  23. Selexipag in the management of pulmonary arterial hypertension: an update

    Article • Drug Healthcare and Patient Safety, August 2019, Dove Medical Press

    Professor of Vascular Physiology Lucie Clapp

  24. Pharmacology of the single isomer, esuberaprost (beraprost-314d) on pulmonary vascular tone, IP receptors and human smooth muscle proliferation in pulmonary hypertension

    Article • Biochemical Pharmacology, August 2019, Elsevier

    Professor of Vascular Physiology Lucie Clapp

  25. Adverse Events of Prostacyclin Mimetics in Pulmonary Arterial Hypertension: A Systematic Review and Meta-Analysis

    Article • Journal of Clinical Medicine, April 2019, MDPI AG

    Professor of Vascular Physiology Lucie Clapp

  26. RALINEPAG REDUCES PULMONARY VASCULAR RESISTANCE (PVR) IN A PHASE 2 STUDY CONFIRMING PRECLINICAL FINDINGS ON PROSTACYCLIN (IP) RECEPTORS IN HUMAN TISSUES

    Article • CHEST Journal, October 2018, Elsevier

    Professor of Vascular Physiology Lucie Clapp

  27. Impact of treprostinil on dynamin-related protein 1 (DRP1) and mitochondrial fragmentation in pulmonary arterial hypertension (PAH).

    Article • September 2018, European Respiratory Society (ERS)

    Professor of Vascular Physiology Lucie Clapp

  28. Prostanoid EP2 Receptors Are Up-Regulated in Human Pulmonary Arterial Hypertension: A Key Anti-Proliferative Target for Treprostinil in Smooth Muscle Cells

    Article • International Journal of Molecular Sciences, August 2018, MDPI AG

    Professor of Vascular Physiology Lucie Clapp

  29. Improving Interpretation of Cardiac Phenotypes and Enhancing Discovery With Expanded Knowledge in the Gene Ontology

    Article • Circulation Genomic and Precision Medicine, February 2018, Wolters Kluwer Health

    Professor of Vascular Physiology Lucie Clapp

  30. THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview

    Article • British Journal of Pharmacology, October 2017, Wiley

    Dr Christopher Southan, Dr Anthony P Davenport, Professor Israel Hanukoglu, Professor Jamie A Davies, Prof daniel hoyer, Professor of Vascular Physiology Lucie Clapp

  31. The non-prostanoid IP receptor agonist, APD811 (ralinepag) has potent antiproliferative and vasorelaxant properties in human pulmonary artery

    Article • September 2017, European Respiratory Society (ERS)

    Professor of Vascular Physiology Lucie Clapp

  32. 5021APD811 (ralinepag), a novel non-prostanoid IP receptor agonist, has potent antiproliferative and vasorelaxant properties in human pulmonary artery

    Article • European Heart Journal, August 2017, Oxford University Press (OUP)

    Professor of Vascular Physiology Lucie Clapp

  33. Prostacyclins have no direct inotropic effect on isolated atrial strips from the normal and pressure-overloaded human right heart

    Article • Pulmonary Circulation, May 2017, SAGE Publications

    Professor of Vascular Physiology Lucie Clapp

  34. Inotropic Effects of Prostacyclins on the Right Ventricle Are Abolished in Isolated Rat Hearts With Right-Ventricular Hypertrophy and Failure

    Article • Journal of Cardiovascular Pharmacology, January 2017, Wolters Kluwer Health

    Professor of Vascular Physiology Lucie Clapp

  35. Abstracts from the 10th World Congress for Microcirculation

    Article • Microcirculation, September 2015, Wiley

    Professor of Vascular Physiology Lucie Clapp

  36. Differential action of beraprost isomers on prostacyclin (IP) receptors and PPARβ in pulmonary arteries

    Article • September 2015, European Respiratory Society (ERS)

    Professor of Vascular Physiology Lucie Clapp

  37. Ex vivo relaxations of pulmonary arteries induced by prostacyclin mimetics are highly dependent of the precontractile agents

    Article • Prostaglandins & Other Lipid Mediators, September 2015, Elsevier

    Professor of Vascular Physiology Lucie Clapp

  38. The mechanistic basis of prostacyclin and its stable analogues in pulmonary arterial hypertension: Role of membrane versus nuclear receptors

    Article • Prostaglandins & Other Lipid Mediators, July 2015, Elsevier

    Professor of Vascular Physiology Lucie Clapp

  39. Inhibition of Phosphodiesterase 2 Augments cGMP and cAMP Signaling to Ameliorate Pulmonary Hypertension

    Article • Circulation, August 2014, Wolters Kluwer Health

    Professor of Vascular Physiology Lucie Clapp

  40. Counteracting effects of treprostinil and endothelin (ET-1) receptor antagonists (ETRAs) on endothelin-1, ETB receptor and ECE-1 levels in pulmonary smooth muscle cells (PASMCs) derived from patients with pulmonary arterial hypertension (PAH)

    Article • Life Sciences, December 2013, Elsevier

    Professor of Vascular Physiology Lucie Clapp

  41. A comparative study of PGI2 mimetics used clinically on the vasorelaxation of human pulmonary arteries and veins, role of the DP-receptor

    Article • Prostaglandins & Other Lipid Mediators, December 2013, Elsevier

    Professor of Vascular Physiology Lucie Clapp

  42. Differential actions of the prostacyclin analogues treprostinil and iloprost and the selexipag metabolite, MRE-269 (ACT-333679) in rat small pulmonary arteries and veins

    Article • Prostaglandins & Other Lipid Mediators, October 2013, Elsevier

    Professor of Vascular Physiology Lucie Clapp

  43. Attenuated vascular responsiveness to K+ channel openers in diabetes mellitus: the differential role of reactive oxygen species

    Article • General Physiology and Biophysics, January 2013, AEPress, s.r.o.

    Dr C R Nwokocha, Professor of Vascular Physiology Lucie Clapp

  44. Binding and activity of the prostacyclin receptor (IP) agonists, treprostinil and iloprost, at human prostanoid receptors: Treprostinil is a potent DP1 and EP2 agonist

    Article • Biochemical Pharmacology, July 2012, Elsevier

    Professor of Vascular Physiology Lucie Clapp

  45. Inhibition of vascular adenosine triphosphate-sensitive potassium channels by sympathetic tone during sepsis

    Article • Critical Care Medicine, April 2012, Wolters Kluwer Health

    Professor of Vascular Physiology Lucie Clapp

  46. Role of prostanoid IP and EP receptors in mediating vasorelaxant responses to PGI2 analogues in rat tail artery: Evidence for Gi/o modulation via EP3 receptors

    Article • European Journal of Pharmacology, March 2011, Elsevier

    Professor of Vascular Physiology Lucie Clapp

  47. Retraction Note: The large-conductance Ca2+-activated K+ channel is essential for innate immunity

    Article • Nature, November 2010, Springer Science + Business Media

    Professor of Vascular Physiology Lucie Clapp

  48. Smooth Muscle Proliferation and Role of the Prostacyclin (IP) Receptor in Idiopathic Pulmonary Arterial Hypertension

    Article • American Review of Respiratory Disease, November 2010, American Thoracic Society

    Professor of Vascular Physiology Lucie Clapp

  49. VARIABLE EFFECTS OF INHIBITING iNOS AND CLOSING THE VASCULAR ATP-SENSITIVE POTASSIUM CHANNEL (VIA ITS PORE-FORMING AND SULFONYLUREA RECEPTOR SUBUNITS) IN ENDOTOXIC SHOCK

    Article • Shock, May 2009, Wolters Kluwer Health

    Professor of Vascular Physiology Lucie Clapp

  50. Different calcium mobilisation pathways underlie the changes in vascular reactivity to norepinephrine and vasopressin in septic shock

    Article • Journal of Infection, November 2008, Elsevier

    Professor of Vascular Physiology Lucie Clapp

  51. Differential effects of vasopressin and norepinephrine on vascular reactivity in a long-term rodent model of sepsis*

    Article • Critical Care Medicine, October 2007, Wolters Kluwer Health

    Professor of Vascular Physiology Lucie Clapp

  52. IP receptor-dependent activation of PPARγ by stable prostacyclin analogues

    Article • Biochemical and Biophysical Research Communications, September 2007, Elsevier

    Professor of Vascular Physiology Lucie Clapp

  53. Stoking Up BK Ca Channels in Hemorrhagic Shock

    Article • Circulation Research, August 2007, Wolters Kluwer Health

    Professor of Vascular Physiology Lucie Clapp

  54. Nuclear translocation of calcineurin Aβ but not calcineurin Aα by platelet-derived growth factor in rat aortic smooth muscle

    Article • AJP Cell Physiology, June 2007, American Physiological Society

    Professor of Vascular Physiology Lucie Clapp

  55. Endothelium-derived hyperpolarization factor (EDHF) is up-regulated in a pig model of acute liver failure

    Article • Scandinavian Journal of Gastroenterology, January 2007, Taylor & Francis

    Professor of Vascular Physiology Lucie Clapp

  56. Vasopressin: Mechanisms of action on the vasculature in health and in septic shock

    Article • Critical Care Medicine, January 2007, Wolters Kluwer Health

    Professor of Vascular Physiology Lucie Clapp

  57. Role of KATP channels in sepsis

    Article • Cardiovascular Research, November 2006, European Society of Cardiology

    Professor of Vascular Physiology Lucie Clapp

  58. Functional Expression of Inward Rectifier Potassium Channels in Cultured Human Pulmonary Smooth Muscle Cells: Evidence for a Major Role of Kir2.4 Subunits

    Article • The Journal of Membrane Biology, September 2006, Springer Science + Business Media

    Professor of Vascular Physiology Lucie Clapp

  59. Evidence that inward rectifier K+ channels mediate relaxation by the PGI2 receptor agonist cicaprost via a cyclic AMP-independent mechanism

    Article • Cardiovascular Research, January 2006, European Society of Cardiology

    Professor of Vascular Physiology Lucie Clapp

  60. Opportunities to Replace the Use of Animals in Sepsis Research

    Article • Alternatives to Laboratory Animals, December 2005, SAGE Publications

    Professor of Vascular Physiology Lucie Clapp

  61. Reversal of life-threatening, drug-related potassium-channel syndrome by glibenclamide

    Article • The Lancet, May 2005, Elsevier

    Professor of Vascular Physiology Lucie Clapp

  62. The pore‐forming subunit of the KATP channel is an important molecular target for LPS‐induced vascular hyporeactivity in vitro

    Article • British Journal of Pharmacology, February 2005, Wiley

    Professor of Vascular Physiology Lucie Clapp

  63. The large-conductance Ca2+-activated K+ channel is essential for innate immunity

    Article • February 2004, Nature

    Professor of Vascular Physiology Lucie Clapp

  64. The BK Channel

    Article • Circulation Research, November 2003, Wolters Kluwer Health

    Professor of Vascular Physiology Lucie Clapp

  65. Do Anionic Phospholipids Serve as Cofactors or Second Messengers for the Regulation of Activity of Cloned ATP-Sensitive K + Channels?

    Article • Circulation Research, October 2003, Wolters Kluwer Health

    Professor of Vascular Physiology Lucie Clapp

  66. Different molecular sites of action for the KATP channel inhibitors, PNU‐99963 and PNU‐37883A

    Article • British Journal of Pharmacology, May 2003, Wiley

    Professor of Vascular Physiology Lucie Clapp

  67. NO contributes to EDHF-like responses in rat small arteries: a role for NO stores

    Article • Cardiovascular Research, January 2003, European Society of Cardiology

    Professor of Vascular Physiology Lucie Clapp

  68. The molecular site of action of KATP channel inhibitors determines their ability to inhibit iNOS-mediated relaxation in rat aorta

    Article • Cardiovascular Research, October 2002, European Society of Cardiology

    Professor of Vascular Physiology Lucie Clapp

  69. Substrate selectivity and sensitivity to inhibition by FK506 and cyclosporin A of calcineurin heterodimers composed of the α or β catalytic subunit

    Article • FEBS Journal, July 2002, Wiley

    Professor of Vascular Physiology Lucie Clapp

  70. Assembly Limits the Pharmacological Complexity of ATP-sensitive Potassium Channels

    Article • Journal of Biological Chemistry, April 2002, Elsevier

    Professor of Vascular Physiology Lucie Clapp

  71. Terlipressin for norepinephrine-resistant septic shock

    Article • The Lancet, April 2002, Elsevier

    Professor of Vascular Physiology Lucie Clapp

  72. Differential Effects of Stable Prostacyclin Analogs on Smooth Muscle Proliferation and Cyclic AMP Generation in Human Pulmonary Artery

    Article • American Journal of Respiratory Cell and Molecular Biology, February 2002, American Thoracic Society

    Professor of Vascular Physiology Lucie Clapp

  73. The Molecular Composition of KATP Channels in Human Pulmonary Artery Smooth Muscle Cells and Their Modulation by Growth

    Article • American Journal of Respiratory Cell and Molecular Biology, January 2002, American Thoracic Society

    Professor of Vascular Physiology Lucie Clapp

  74. Temporal variation in endotoxin‐induced vascular hyporeactivity in a rat mesenteric artery organ culture model

    Article • British Journal of Pharmacology, June 2001, Wiley

    Professor of Vascular Physiology Lucie Clapp

  75. Calcium Modulation of Vascular Smooth Muscle ATP-Sensitive K + Channels

    Article • Circulation Research, November 2000, Wolters Kluwer Health

    Professor of Vascular Physiology Lucie Clapp

  76. Evidence that Ca2+-activated K+ channels play a major role in mediating the vascular effects of iloprost and cicaprost

    Article • European Journal of Pharmacology, September 1998, Elsevier

    Professor of Vascular Physiology Lucie Clapp

  77. Potassium channels in the vasculature

    Article • Current Opinion in Nephrology & Hypertension, January 1998, Wolters Kluwer Health

    Professor of Vascular Physiology Lucie Clapp

  78. Abnormal Activation of K+Channels Underlies Relaxation to Bacterial Lipopolysaccharide in Rat Aorta

    Article • Biochemical and Biophysical Research Communications, July 1996, Elsevier

    Professor of Vascular Physiology Lucie Clapp

  79. Ca(2+)-activated Cl- currents in pulmonary arterial myocytes

    Article • AJP Heart and Circulatory Physiology, May 1996, American Physiological Society

    Professor of Vascular Physiology Lucie Clapp

  80. Regulation of glibenclamide-sensitive K+ current by nucleotide phosphates in isolated rabbit pulmonary myocytes

    Article • Cardiovascular Research, September 1995, European Society of Cardiology

    Professor of Vascular Physiology Lucie Clapp

  81. Regulation of glibenclamide-sensitive K+ current by nucleotide phosphates in isolated rabbit pulmonary myocytes

    Article • Cardiovascular Research, September 1995, Oxford University Press (OUP)

    Professor of Vascular Physiology Lucie Clapp

  82. Ca(2+)-activated Cl- and K+ channels and their modulation by endothelin-1 in rat pulmonary arterial smooth muscle cells

    Article • Quarterly Journal of Experimental Physiology and Cognate Medical Sciences, September 1995, Wiley

    Professor of Vascular Physiology Lucie Clapp

  83. KATP channels: fact or artefact?: commentaries

    Article • Cardiovascular Research, June 1994, European Society of Cardiology

    Professor of Vascular Physiology Lucie Clapp

  84. Properties of the ATP-sensitive K+ current activated by levcromakalim in isolated pulmonary arterial myocytes

    Article • The Journal of Membrane Biology, June 1994, Springer Science + Business Media

    Professor of Vascular Physiology Lucie Clapp

  85. Augmentation by intracellular ATP of the delayed rectifier current independently of the glibenclamide-sensitive K-current in rabbit arterial myocytes

    Article • British Journal of Pharmacology, April 1994, Wiley

    Professor of Vascular Physiology Lucie Clapp

  86. ATP-sensitive K+ channels mediate vasodilation produced by lemakalim in rabbit pulmonary artery

    Article • AJP Heart and Circulatory Physiology, June 1993, American Physiological Society

    Professor of Vascular Physiology Lucie Clapp

  87. Role for diacylglycerol in mediating the actions of ACh on M-current in gastric smooth muscle cells

    Article • AJP Cell Physiology, December 1992, American Physiological Society

    Professor of Vascular Physiology Lucie Clapp

  88. ATP-sensitive K+ channels regulate resting potential of pulmonary arterial smooth muscle cells

    Article • AJP Heart and Circulatory Physiology, March 1992, American Physiological Society

    Professor of Vascular Physiology Lucie Clapp

  89. Both membrane stretch and fatty acids directly activate large conductance Ca2+‐activated K+ channels in vascular smooth muscle cells

    Article • FEBS Letters, February 1992, Wiley

    Professor of Vascular Physiology Lucie Clapp

  90. Outward currents in rabbit pulmonary artery cells dissociated with a new technique

    Article • Quarterly Journal of Experimental Physiology and Cognate Medical Sciences, September 1991, Wiley

    Professor of Vascular Physiology Lucie Clapp

  91. Modulation of calcium movements by nitroprusside in isolated vascular smooth muscle cells

    Article • Pflügers Archiv - European Journal of Physiology, June 1991, Springer Science + Business Media

    Professor of Vascular Physiology Lucie Clapp

  92. Dual regulation of M current in gastric smooth muscle cells: β-adrenergic-muscarinic antagonism

    Article • Pflügers Archiv - European Journal of Physiology, November 1990, Springer Science + Business Media

    Professor of Vascular Physiology Lucie Clapp

  93. Regulation of one type of Ca 2+ current in smooth muscle cells by diacylglycerol and acetylcholine

    Article • The FASEB Journal, June 1988, Wiley

    Professor of Vascular Physiology Lucie Clapp

  94. Neurotransmitter Regulation of Ionic Channels in Freshly Dissociated Smooth Muscle Cellsa

    Article • Annals of the New York Academy of Sciences, June 1988, Wiley

    Professor of Vascular Physiology Lucie Clapp

  95. Acetylcholine increases voltage-activated Ca2+ current in freshly dissociated smooth muscle cells.

    Article • Proceedings of the National Academy of Sciences, April 1987, Proceedings of the National Academy of Sciences

    Professor of Vascular Physiology Lucie Clapp

  96. Endothelial‐dependent relaxant actions of carbachol and substance P in arterial smooth muscle

    Article • British Journal of Pharmacology, May 1986, Wiley

    Professor of Vascular Physiology Lucie Clapp

  97. The diverse effects of noradrenaline and other stimulants on 86Rb and 42K efflux in rabbit and guinea‐pig arterial muscle.

    Article • The Journal of Physiology, October 1984, Wiley

    Professor of Vascular Physiology Lucie Clapp