All Stories

  1. The Contribution of Genetic Sequencing Information to the Identification and Functional Characterization of Two-Pore Domain Potassium (K2P) Channels as Viable Therapeutic Targets
  2. Screening for atrial fibrillation in care homes using pulse palpation and the AliveCor Kardia Mobile® device: a comparative cross-sectional pilot study
  3. The Concise Guide to PHARMACOLOGY 2023/24: Catalytic receptors
  4. The Concise Guide to PHARMACOLOGY 2023/24: Enzymes
  5. The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors
  6. The Concise Guide to PHARMACOLOGY 2023/24: Introduction and Other Protein Targets
  7. The Concise Guide to PHARMACOLOGY 2023/24: Ion channels
  8. The Concise Guide to PHARMACOLOGY 2023/24: Nuclear hormone receptors
  9. The Concise Guide to PHARMACOLOGY 2023/24: Transporters
  10. A KCNB1 gain of function variant causes developmental delay and speech apraxia but not seizures
  11. HIV and Schistosoma Co-Exposure Leads to Exacerbated Pulmonary Endothelial Remodeling and Dysfunction Associated with Altered Cytokine Landscape
  12. Gain and loss of TASK3 channel function and its regulation by novel variation cause KCNK9 imprinting syndrome
  13. Aprepitant is a novel, selective activator of the K2P channel TRAAK
  14. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Catalytic receptors
  15. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Enzymes
  16. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein‐coupled receptors
  17. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Introduction and Other Protein Targets
  18. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Ion channels
  19. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Nuclear hormone receptors
  20. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Transporters
  21. Block of TREK and TRESK K2P channels by lamotrigine and two derivatives sipatrigine and CEN-092
  22. The Prostacyclin Analogue, Treprostinil, Used in the Treatment of Pulmonary Arterial Hypertension, is a Potent Antagonist of TREK-1 and TREK-2 Potassium Channels
  23. Pharmacological Approaches to Studying Potassium Channels
  24. A “Target Class” Screen to Identify Activators of Two-Pore Domain Potassium (K2P) Channels
  25. Heterologous Expression of Ion Channels in Mammalian Cell Lines
  26. TRESK is a key regulator of nocturnal suprachiasmatic nucleus dynamics and light adaptive responses
  27. TASK-3 Two-Pore Potassium Channels drive neuronal excitability of the circadian clock and entrainment to challenging light environments
  28. Opportunistic screening for atrial fibrillation by clinical pharmacists in UK general practice during the influenza vaccination season: A cross-sectional feasibility study
  29. Two-Pore Domain Potassium Channels as Drug Targets: Anesthesia and Beyond
  30. Pharmacists detecting atrial fibrillation in general practice: a qualitative focus group study
  31. THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Catalytic receptors
  32. THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Enzymes
  33. THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: G protein-coupled receptors
  34. THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Introduction and Other Protein Targets
  35. THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Ion channels
  36. THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Nuclear hormone receptors
  37. THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Transporters
  38. Pranlukast is a novel small molecule activator of the two-pore domain potassium channel TREK2
  39. Pharmacologically reversible, loss of function mutations in the TM2 and TM4 inner pore helices of TREK-1 K2P channels
  40. Effects of the ventilatory stimulant, doxapram on human TASK‐3 (KCNK9, K2P9.1) channels and TASK‐1 (KCNK3, K2P3.1) channels
  41. Infection in pulmonary vascular diseases: Would another consortium really be the way to go?
  42. Characterisation and regulation of wild type and mutant TASK-1 two pore domain potassium channels indicated in pulmonary arterial hypertension
  43. HIV transgene expression impairs K+ channel function in the pulmonary vasculature
  44. Activation of TREK currents by riluzole in three subgroups of cultured mouse nodose ganglion neurons
  45. Pharmacists detecting atrial fibrillation (PDAF) in primary care during the influenza vaccination season: a multisite, cross-sectional screening protocol
  46. GI-530159, a novel, selective, mechanosensitive two-pore-domain potassium (K2P ) channel opener, reduces rat dorsal root ganglion neuron excitability
  47. TASK-1 (KCNK3) channels in the lung: from cell biology to clinical implications
  48. Terbinafine is a novel and selective activator of the two-pore domain potassium channel TASK3
  49. Enhanced inflammatory cell profiles in schistosomiasis-induced pulmonary vascular remodeling
  50. Aristolochic acid, a plant extract used in the treatment of pain and linked to Balkan endemic nephropathy, is a regulator of K2P channels
  51. Two-pore domain potassium channels: potential therapeutic targets for the treatment of pain
  52. Influence of the N Terminus on the Biophysical Properties and Pharmacology of TREK1 Potassium Channels
  53. Enhancement of Current through Trek1 Two Pore Domain Channels by Flufenamic Acid
  54. Recovery of Current through Mutated TASK3 Potassium Channels Underlying Birk Barel Syndrome
  55. Enhancement of TWIK-related Acid-sensitive Potassium Channel 3 (TASK3) Two-pore Domain Potassium Channel Activity by Tumor Necrosis Factor  
  56. GuideToPharmacology.org - an update
  57. Guide to Receptors and Channels (GRAC), 5th edition
  58. Trafficking of Neuronal Two Pore Domain Potassium Channels
  59. SYMPOSIUM REVIEW: Gating of two pore domain potassium channels
  60. Ion channels as novel therapeutic targets in the treatment of pain
  61. Dominant Negative Effects of a Non-conducting TREK1 Splice Variant Expressed in Brain
  62. Guide to Receptors and Channels (GRAC), 4th edition
  63. The M1P1 Loop of TASK3 K2P Channels Apposes the Selectivity Filter and Influences Channel Function
  64. Guide to Receptors and Channels (GRAC), 3rd edition
  65. Identification of a region in the TASK3 two pore domain potassium channel that is critical for its blockade by methanandamide
  66. TASK-3 Two-Pore Domain Potassium Channels Enable Sustained High-Frequency Firing in Cerebellar Granule Neurons
  67. Gαq-Mediated Regulation of TASK3 Two-Pore Domain Potassium Channels: The Role of Protein Kinase C
  68. Guide to Receptors and Channels, 2nd edition (2007 Revision)
  69. Neuronal two-pore-domain potassium channels and their regulation by G protein-coupled receptors
  70. Zinc and copper: Pharmacological probes and endogenous modulators of neuronal excitability
  71. Guide to Receptors and Channels, 2nd edition
  72. The in Vivo Contributions of TASK-1-Containing Channels to the Actions of Inhalation Anesthetics, the α2 Adrenergic Sedative Dexmedetomidine, and Cannabinoid Agonists
  73. Modifying the Subunit Composition of TASK Channels Alters the Modulation of a Leak Conductance in Cerebellar Granule Neurons
  74. Guide to Receptors and Channels, 1st Edition (2005 revision)
  75. Inhibition of the human two-pore domain potassium channel, TREK-1, by fluoxetine and its metabolite norfluoxetine
  76. Selective block of the human 2-P domain potassium channel, TASK-3, and the native leak potassium current, IKSO, by zinc
  77. Two-Pore-Domain K+ Channels Are a Novel Target for the Anesthetic Gases Xenon, Nitrous Oxide, and Cyclopropane
  78. Neuronal ion channels and their sensitivity to extremely low frequency weak electric field effects
  79. What are the roles of the many different types of potassium channel expressed in cerebellar granule cells?
  80. What are the roles of the many different types of potassium channel expressed in cerebellar granule cells?
  81. Background potassium channels move into focus
  82. Pharmacological characterization of a non-inactivating outward current observed in mouse cerebellar Purkinje neurones
  83. Inhibition of the potassium current IKSO, in cerebellar granule cells, by the inhibitors of MEK1 activation, PD 98059 and U 0126
  84. MAMMALIAN TWO-PORE DOMAIN POTASSIUM CHANNELS
  85. TiPS nomenclature supplement 2001
  86. The role of Ca2+stores in the muscarinic inhibition of the K+currentIK(SO)in neonatal rat cerebellar granule cells
  87. Purinergic and muscarinic receptor activation activates a common calcium entry pathway in rat neocortical neurons and glial cells
  88. A functional role for the two-pore domain potassium channel TASK-1 in cerebellar granule neurons
  89. A functional role for the two-pore domain potassium channel TASK-1 in cerebellar granule neurons
  90. Inhibition of delayed rectifier K+conductance in cultured rat cerebellar granule neurons by activation of calcium-permeable AMPA receptors
  91. Inhibition of neuronal KV potassium currents by the antidepressant drug, fluoxetine
  92. Inhibition by inorganic ions of a sustained calcium signal evoked by activation of mGlu5 receptors in rat cortical neurons and glia
  93. Activation of group I metabotropic glutamate receptors elicits pH changes in cultured rat cortical glia and neurons
  94. Characterization of the hyperpolarization-activated chloride current in dissociated rat sympathetic neurons
  95. Voltage-activated potassium channels in mammalian neurons and their block by novel pharmacological agents
  96. Ion Channels: Molecules in Action. Edited by D. J.Aidleyand P. R.Stanfield. Pp. 340. Cambridge University Press, 1996. £17.95 paperback, ISBN 0521 49882 1. £50.00 hardback, ISBN 0 521 49531 8
  97. Is eag the answer to the M-current?
  98. Effects on K+ currents in rat cerebellar granule neurones of a membrane-permeable analogue of the calcium chelator BAPTA
  99. A non-inactivating K+ current sensitive to muscarinic receptor activation in rat cultured cerebellar granule neurons.
  100. Potent block of potassium currents in rat isolated sympathetic neurones by the uncharged form of amitriptyline and related tricyclic compounds
  101. Methods in neurosciences volume 19: Ion channels of excitable cells
  102. Multiple G-protein-coupled pathways inhibit N-type Ca channels of neurons
  103. Modulation of the gating of the transient outward potassium current of rat isolated cerebellar granule neurons by lanthanum
  104. Block of potassium currents in rat isolated sympathetic neurones by tricyclic antidepressants and structurally related compounds
  105. Characterization of muscarinic receptor subtypes inhibiting Ca2+ current and M current in rat sympathetic neurons.
  106. Inhibition of N- and L-type calcium channels by muscarinic receptor activation in rat sympathetic neurons
  107. 5-HT3 receptor channels in dissociated rat superior cervical ganglion neurons.
  108. Conductance and kinetic properties of single nicotinic acetylcholine receptor channels in rat sympathetic neurones.
  109. Intracellular Ca2+ buffers disrupt muscarinic suppression of Ca2+ current and M current in rat sympathetic neurons.
  110. Activation of glutamate receptors and glutamate uptake in identified macroglial cells in rat cerebellar cultures.
  111. Rectification of currents activated by nicotinic acetylcholine receptors in rat sympathetic ganglion neurones.
  112. Chapter 5 Function of nicotinic synapses
  113. Acetylcholine receptor channels and their block by clonidine in cultured bovine chromaffin cells.
  114. Nicotinic acetylcholine receptors of nerve and muscle: Functional aspects
  115. Single-Channel and Whole-Cell Currents Evoked by Acetylcholine in Dissociated Sympathetic Neurons of the Rat
  116. Interactions between the effects of yohimbine, clonidine and [Ca]o on the electrical response of the mouse vas deferens
  117. Ion channels activated by acetylcholine and γ-aminobutyric acid in freshly dissociated sympathetic neurones of the rat
  118. Facilitation at single release sites of a sympathetic neuroeffector junction in the mouse.
  119. α-ADRENORECEPTORS AND FACILITATION AT A SYMPATHETIC NEUROEFFECTOR JUNCTION
  120. Neuronal Potassium Channels