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  1. Involvement of increased p53 expression in the decrease of mitochondrial DNA copy number and increase of SUVmax of FDG-PET scan in esophageal squamous cell carcinoma

    Article • Mitochondrion, July 2019, Elsevier

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  2. Alterations of oxygen consumption and extracellular acidification rates by glutamine in PBMCs of SLE patients

    Article • Mitochondrion, January 2019, Elsevier

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  3. Low mitochondrial DNA copy number of resected cecum appendix correlates with high severity of acute appendicitis

    Article • Journal of the Formosan Medical Association, January 2019, Elsevier

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  4. Assessment of zero-valent iron-based nanotherapeutics for ferroptosis induction and resensitization strategy in cancer cells

    Article • Biomaterials Science, January 2019, Royal Society of Chemistry

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  5. Sirt3 is required in adipogenic differentiation of stem cells and plays a role in type 2 diabetes.

    Article • Free Radical Research, July 2018, Taylor & Francis

    Professor and Director Yau-Huei Wei, Yu-Ting Wu, Yau-Huei Wei

  6. Generation of two isogenic human induced pluripotent stem cell lines from a 15 year-old female patient with MERRF syndrome and A8344G mutation of mitochondrial DNA

    Article • Stem Cell Research, July 2018, Elsevier

    Professor and Director Yau-Huei Wei, Yau-Huei Wei, Professor Hsin-Chen Lee

  7. Essential role of connective tissue growth factor (CTGF) in transforming growth factor-β1 (TGF-β1)-induced myofibroblast transdifferentiation from Graves’ orbital fibroblasts

    Article • Scientific Reports, May 2018, Springer Science + Business Media

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  8. ATOH1/RFX1/RFX3 transcription factors facilitate the differentiation and characterisation of inner ear hair cell-like cells from patient-specific induced pluripotent stem cells harbouring A8344G mutation of mitochondrial DNA

    Article • Cell Death and Disease, April 2018, Springer Science + Business Media

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  9. Sirt3 activates mitochondrial enzymes and antioxidant defense in differentiating stem cells.

    Article • Experimental Biology and Medicine, March 2018, SAGE Publications

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  10. Connective tissue growth factor decreases mitochondrial metabolism through ubiquitin-mediated degradation of mitochondrial transcription factor A in oral squamous cell carcinoma

    Article • Journal of the Formosan Medical Association, March 2018, Elsevier

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  11. Generation of an induced pluripotent stem cell (iPSC) line from a 40-year-old patient with the A8344G mutation of mitochondrial DNA and MERRF (myoclonic epilepsy with ragged red fibers) syndrome

    Article • Stem Cell Research, March 2018, Elsevier

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  12. Promoter analysis and transcriptional regulation of human carbonic anhydrase VIII gene in a MERRF disease cell model

    Article • Archives of Biochemistry and Biophysics, March 2018, Elsevier

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  13. Generation of an induced pluripotent stem cell line from a 39-year-old female patient with severe-to-profound non-syndromic sensorineural hearing loss and a A1555G mutation in the mitochondrial MTRNR1 gene

    Article • Stem Cell Research, December 2017, Elsevier

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  14. Role of mitochondrial function in the invasiveness of human colon cancer cells

    Article • Oncology Reports, November 2017, Spandidos Publications

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  15. Significant Association Between Low Mitochondrial DNA Content in Peripheral Blood Leukocytes and Ischemic Stroke

    Article • Journal of the American Heart Association, November 2017, Wolters Kluwer Health

    Professor and Director Yau-Huei Wei

  16. AB001. Low mitochondrial DNA copy number is associated with low mitochondrial DNA integrity and advanced T-status in non-small cell lung cancer

    Article • Journal of Thoracic Disease, October 2017, AME Publishing Company

    Professor and Director Yau-Huei Wei

  17. AB002. Relationship between mitochondrial DNA copy number and maximum standard uptake value of 18F-fluorodeoxyglucose positron emission tomography scan in esophageal squamous cell carcinoma

    Article • Journal of Thoracic Disease, October 2017, AME Publishing Company

    Professor and Director Yau-Huei Wei

  18. Role of mitochondrial dysfunction and dysregulation of Ca2+ homeostasis in the pathophysiology of insulin resistance and type 2 diabetes

    Article • Journal of Biomedical Science, September 2017, Springer Science + Business Media

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  19. Peptide-mediated delivery of donor mitochondria improves mitochondrial function and cell viability in human cybrid cells with the MELAS A3243G mutation

    Article • Scientific Reports, September 2017, Springer Science + Business Media

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  20. ROS and Oxidative Stress in Stem Cells

    Article • Oxidative Medicine and Cellular Longevity, January 2017, Hindawi Publishing Corporation

    Professor and Director Yau-Huei Wei, Professor Hsin-Chen Lee, Magdalena Skonieczna, Yau-Huei Wei

  21. The pathogenesis of systemic lupus erythematosus - From the viewpoint of oxidative stress and mitochondrial dysfunction

    Article • Mitochondrion, September 2016, Elsevier

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  22. Expression and clinical significance of connective tissue growth factor (CTGF) in Graves' ophthalmopathy

    Article • British Journal of Ophthalmology, August 2016, BMJ

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  23. Hyaluronan Upregulates Mitochondrial Biogenesis and Reduces Adenoside Triphosphate Production for Efficient Mitochondrial Function in Slow-Proliferating Human Mesenchymal Stem Cells

    Article • Stem Cells, July 2016, Wiley

    Professor Lynn LH Huang, Professor and Director Yau-Huei Wei, Yau-Huei Wei

  24. Role of Mitochondrial DNA Copy Number Alteration in Human Renal Cell Carcinoma

    Article • International Journal of Molecular Sciences, May 2016, MDPI AG

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  25. Mitochondria in mesenchymal stem cell biology and cell therapy: From cellular differentiation to mitochondrial transfer

    Article • Seminars in Cell and Developmental Biology, April 2016, Elsevier

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  26. Cigarette Smoke Extract-Induced Oxidative Stress and Fibrosis-Related Genes Expression in Orbital Fibroblasts from Patients with Graves’ Ophthalmopathy

    Article • Oxidative Medicine and Cellular Longevity, January 2016, Hindawi Publishing Corporation

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  27. Alteration of Connective Tissue Growth Factor (CTGF) Expression in Orbital Fibroblasts from Patients with Graves’ Ophthalmopathy

    Article • PLoS ONE, November 2015, PLOS

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  28. 2-Deoxy-d-Glucose Can Complement Doxorubicin and Sorafenib to Suppress the Growth of Papillary Thyroid Carcinoma Cells

    Article • PLoS ONE, July 2015, PLOS

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  29. The Core Pattern Analysis on Chinese Herbal Medicine for Sjögren's syndrome: A Nationwide Population-Based Study

    Article • Scientific Reports, April 2015, Nature

    Dr. Hung-Rong Yen, Professor and Director Yau-Huei Wei, Yau-Huei Wei

  30. Correlation of NADH fluorescence lifetime and oxidative phosphorylation metabolism in the osteogenic differentiation of human mesenchymal stem cell

    Article • Journal of Biomedical Optics, January 2015, SPIE

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  31. Transient Increase in Circulating Myeloid-Derived Suppressor Cells after Partial Bladder Outlet Obstruction

    Article • The Journal of Urology, November 2014, Wolters Kluwer Health

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  32. Special issue on “Oxidative stress and mitochondrial alterations in aging and disease”

    Article • Free Radical Research, August 2014, Taylor & Francis

    Professor and Director Yau-Huei Wei

  33. Differential patterns of effects of age and sex on metabolic syndrome in Taiwan: Implication for the inadequate internal consistency of the current criteria

    Article • Diabetes Research and Clinical Practice, August 2014, Elsevier

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  34. Cisd2 mediates lifespan: is there an interconnection among Ca2+homeostasis, autophagy, and lifespan?

    Article • Free Radical Research, July 2014, Taylor & Francis

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  35. Roles of sirtuins in the regulation of antioxidant defense and bioenergetic function of mitochondria under oxidative stress

    Article • Free Radical Research, July 2014, Taylor & Francis

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  36. Cisd2 modulates the differentiation and functioning of adipocytes by regulating intracellular Ca2+ homeostasis

    Article • Human Molecular Genetics, May 2014, Oxford University Press (OUP)

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  37. Effects of carbonic anhydrase-related protein VIII on human cells harbouring an A8344G mitochondrial DNA mutation

    Article • Biochemical Journal, April 2014, Portland Press Ltd.

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  38. Role of AMPK-mediated adaptive responses in human cells with mitochondrial dysfunction to oxidative stress

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, April 2014, Elsevier

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  39. Mitochondrial DNA association study of type 2 diabetes with or without ischemic stroke in Taiwan

    Article • BMC Research Notes, January 2014, Springer Science + Business Media

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  40. Inhibitory Effects of Hypoxia on Metabolic Switch and Osteogenic Differentiation of Human Mesenchymal Stem Cells

    Article • Stem Cells, December 2013, Oxford University Press (OUP)

    Yau-Huei Wei, Professor and Director Yau-Huei Wei

  41. Integrated three-dimensional system-on-chip for direct quantitative detection of mitochondrial DNA mutation in affected cells

    Article • Biosensors and Bioelectronics, October 2013, Elsevier

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  42. Isolation and Characterization of a Novel Strain of Mesenchymal Stem Cells from Mouse Umbilical Cord: Potential Application in Cell-Based Therapy

    Article • PLoS ONE, August 2013, PLOS

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  43. Resveratrol Impedes the Stemness, Epithelial-Mesenchymal Transition, and Metabolic Reprogramming of Cancer Stem Cells in Nasopharyngeal Carcinoma through p53 Activation

    Article • Evidence-based Complementary and Alternative Medicine, January 2013, Hindawi Publishing Corporation

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  44. Mitochondrial Dysfunction in Insulin Insensitivity and Type 2 Diabetes and New Insights for Their Prevention and Management

    Article • December 2012, IntechOpen

    Professor and Director Yau-Huei Wei

  45. Functional Recovery of Human Cells Harbouring the Mitochondrial DNA Mutation MERRF A8344G via Peptide-Mediated Mitochondrial Delivery

    Article • Neurosignals, September 2012, Karger Publishers

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  46. High Mitochondrial DNA Copy Number and Bioenergetic Function Are Associated with Tumor Invasion of Esophageal Squamous Cell Carcinoma Cell Lines

    Article • International Journal of Molecular Sciences, September 2012, MDPI AG

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  47. Cigarette Smoking and hOGG1 Ser326Cys Polymorphism are Associated with 8-OHdG Accumulation on Mitochondrial DNA in Thoracic Esophageal Squamous Cell Carcinoma

    Article • Annals of Surgical Oncology, September 2012, Springer Science + Business Media

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  48. Leukocyte Mitochondrial DNA Alteration in Systemic Lupus Erythematosus and Its Relevance to the Susceptibility to Lupus Nephritis

    Article • International Journal of Molecular Sciences, July 2012, MDPI AG

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  49. Mitochondrial bioenergetic function and metabolic plasticity in stem cell differentiation and cellular reprogramming

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, May 2012, Elsevier

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  50. Associated microsatellite alterations in mitochondrial DNA and in TP53 in thoracic esophageal squamous cell carcinoma

    Article • Oncology Reports, April 2012, Spandidos Publications

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  51. AMPK-mediated increase of glycolysis as an adaptive response to oxidative stress in human cells: Implication of the cell survival in mitochondrial diseases

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, February 2012, Elsevier

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  52. Mitochondria and Aging

    Article • December 2011, Springer Science + Business Media

    Professor and Director Yau-Huei Wei, Professor Hsin-Chen Lee

  53. Oxidative Stress and its Biochemical Consequences in Mitochondrial DNA Mutation-Associated Diseases: Implications of Redox Therapy for Mitochondrial Diseases

    Article • November 2011, Wiley

    Professor and Director Yau-Huei Wei

  54. Induction of primitive pigment cell differentiation by visible light (helium–neon laser): a photoacceptor-specific response not replicable by UVB irradiation

    Article • Journal of Molecular Medicine, October 2011, Springer Science + Business Media

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  55. The Cross-Talk Between Mitochondria and the Nucleus in the Response to Oxidative Stress Associated with Mitochondrial Dysfunction in Mitochondrial Encephalomyopathies

    Article • September 2011, IntechOpen

    Professor and Director Yau-Huei Wei

  56. The Effect of Photo-oxidative Stress and Inflammatory Cytokine on Complement Factor H Expression in Retinal Pigment Epithelial Cells

    Article • Investigative Ophthalmology & Visual Science, August 2011, Association for Research in Vision and Ophthalmology (ARVO)

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  57. Increased penile expression of transforming growth factor and elevated systemic oxidative stress in rabbits with chronic partial bladder outlet obstruction

    Article • International Journal of Andrology, June 2011, Wiley

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  58. Aberrant Cell Proliferation by Enhanced Mitochondrial Biogenesis via mtTFA in Arsenical Skin Cancers

    Article • American Journal Of Pathology, May 2011, Elsevier

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  59. Abstract 482: High CD44/CD24 expressive cells presented cancer stem cell characteristics and undergo mitochondrial resetting and metabolic shift in nasopharyngeal carcinoma

    Article • April 2011, American Association for Cancer Research (AACR)

    Professor and Director Yau-Huei Wei

  60. Increase of reduced nicotinamide adenine dinucleotide fluorescence lifetime precedes mitochondrial dysfunction in staurosporine-induced apoptosis of HeLa cells

    Article • Journal of Biomedical Optics, January 2011, SPIE

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  61. Increase of 8-Hydroxy-2′-Deoxyguanosine in Aqueous Humor of Patients with Exudative Age-Related Macular Degeneration

    Article • Investigative Ophthalmology & Visual Science, November 2010, Association for Research in Vision and Ophthalmology (ARVO)

    Professor and Director Yau-Huei Wei

  62. Oxidative stress biomarkers in urine and plasma of rabbits with partial bladder outlet obstruction

    Article • BJU International, September 2010, Wiley

    Professor and Director Yau-Huei Wei, Yau-Huei Wei

  63. Determination of the minimal melatonin exposure required to induce osteoblast differentiation from human mesenchymal stem cells and these effects on downstream signaling pathways

    Article • Journal of Pineal Research, July 2010, Wiley

    Professor and Director Yau-Huei Wei

  64. Mitochondrial dysfunction in insulin insensitivity: implication of mitochondrial role in type 2 diabetes

    Article • Annals of the New York Academy of Sciences, July 2010, Wiley

    Professor and Director Yau-Huei Wei

  65. Mitochondrial respiratory dysfunction-elicited oxidative stress and posttranslational protein modification in mitochondrial diseases

    Article • Annals of the New York Academy of Sciences, July 2010, Wiley

    Professor and Director Yau-Huei Wei

  66. Mitochondrial DNA Mutation-Elicited Oxidative Stress, Oxidative Damage, and Altered Gene Expression in Cultured Cells of Patients with MERRF Syndrome

    Article • Molecular Neurobiology, April 2010, Springer Science + Business Media

    Professor and Director Yau-Huei Wei

  67. Somatic mutations of mitochondrial genome in hepatocellular carcinoma

    Article • Mitochondrion, March 2010, Elsevier

    Professor and Director Yau-Huei Wei, Professor Hsin-Chen Lee

  68. Upregulation of mitochondrial function and antioxidant defense in the differentiation of stem cells

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, March 2010, Elsevier

    Professor and Director Yau-Huei Wei

  69. The role of mitochondrial DNA alterations in esophageal squamous cell carcinomas

    Article • Journal of Thoracic and Cardiovascular Surgery, January 2010, Elsevier

    Professor and Director Yau-Huei Wei

  70. Mitochondrial Respiratory Function Decline in Aging and Life-Span Extension by Caloric Restriction

    Article • January 2010, Springer Science + Business Media

    Professor and Director Yau-Huei Wei

  71. Response to the increase of oxidative stress and mutation of mitochondrial DNA in aging

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, October 2009, Elsevier

    Professor and Director Yau-Huei Wei

  72. Role of Reactive Oxygen Species-elicited Apoptosis in the Pathophysiology of Mitochondrial and Neurodegenerative Diseases Associated With Mitochondrial DNA Mutations

    Article • Journal of the Formosan Medical Association, August 2009, Elsevier

    Professor and Director Yau-Huei Wei

  73. Activation of PKCδ and ERK1/2 in the sensitivity to UV-induced apoptosis of human cells harboring 4977 bp deletion of mitochondrial DNA

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, August 2009, Elsevier

    Professor and Director Yau-Huei Wei

  74. The difference in oxidative stress of the blood between using 5% glucose water and distilled water as the irrigant for BPH patients undergoing transurethral resection of the prostate

    Article • World Journal of Urology, June 2009, Springer Science + Business Media

    Professor and Director Yau-Huei Wei

  75. Fluorescence Supravital Stain of Human Sperm: Correlation with Sperm Motility Measured by a Transmembrane Migration Method/Supravital-Fluoreszenz-Färbung von menschlichen Spermatozoen: Korrelation zur Spermatozoenmotilität (Messung mittels Transmembran-Mi

    Article • Andrologia, April 2009, Wiley

    Professor and Director Yau-Huei Wei

  76. Low copy number and high 4977 deletion of mitochondrial DNA in uterosacral ligaments are associated with pelvic organ prolapse progression

    Article • International Urogynecology Journal, April 2009, Springer Science + Business Media

    Professor and Director Yau-Huei Wei

  77. Mitochondrial dysfunction-induced amphiregulin upregulation mediates chemo-resistance and cell migration in HepG2 cells

    Article • Cellular and Molecular Life Sciences, April 2009, Springer Science + Business Media

    Professor and Director Yau-Huei Wei, Professor Hsin-Chen Lee

  78. Prognostic Variables in Thoracic Esophageal Squamous Cell Carcinoma

    Article • The Annals of Thoracic Surgery, April 2009, Elsevier

    Professor and Director Yau-Huei Wei

  79. Mitochondrial DNA Instability and Metabolic Shift in Human Cancers

    Article • International Journal of Molecular Sciences, February 2009, MDPI AG

    Professor and Director Yau-Huei Wei, Professor Hsin-Chen Lee

  80. Peripheral blood mitochondrial DNA content and dysregulation of glucose metabolism

    Article • Diabetes Research and Clinical Practice, January 2009, Elsevier

    Professor and Director Yau-Huei Wei, Professor Hsin-Chen Lee

  81. GST M1 Polymorphism Associates with DNA Oxidative Damage and Mortality among Hemodialysis Patients

    Article • Journal of the American Society of Nephrology, December 2008, American Society of Nephrology

    Professor and Director Yau-Huei Wei

  82. Oxidative stress in patients with Graves' ophthalmopathy: relationship between oxidative DNA damage and clinical evolution

    Article • Eye, October 2008, Springer Science + Business Media

    Professor and Director Yau-Huei Wei

  83. Intravenous Iron Exacerbates Oxidative DNA Damage in Peripheral Blood Lymphocytes in Chronic Hemodialysis Patients

    Article • Journal of the American Society of Nephrology, May 2008, American Society of Nephrology

    Professor and Director Yau-Huei Wei

  84. Increase of oxidative stress in human sperm with lower motility

    Article • Fertility and Sterility, May 2008, Elsevier

    Professor and Director Yau-Huei Wei

  85. Coordinated Changes of Mitochondrial Biogenesis and Antioxidant Enzymes During Osteogenic Differentiation of Human Mesenchymal Stem Cells

    Article • Stem Cells, April 2008, Wiley

    Professor and Director Yau-Huei Wei

  86. Attenuation of Oxidative Stress After Varicocelectomy in Subfertile Patients With Varicocele

    Article • The Journal of Urology, February 2008, Wolters Kluwer Health

    Professor and Director Yau-Huei Wei

  87. Depletion of mitochondrial DNA in leukocytes of patients with poly-Q diseases

    Article • Journal of the Neurological Sciences, January 2008, Elsevier

    Professor and Director Yau-Huei Wei

  88. Differentiation of apoptosis from necrosis by dynamic changes of reduced nicotinamide adenine dinucleotide fluorescence lifetime in live cells

    Article • Journal of Biomedical Optics, January 2008, SPIE

    Professor and Director Yau-Huei Wei

  89. Reduced nicotinamide adenine dinucleotide fluorescence lifetime separates human mesenchymal stem cells from differentiated progenies

    Article • Journal of Biomedical Optics, January 2008, SPIE

    Professor and Director Yau-Huei Wei

  90. Mitochondrial DNA alterations in blood of the humans exposed to N,N-dimethylformamide

    Article • Chemico-Biological Interactions, February 2007, Elsevier

    Professor and Director Yau-Huei Wei

  91. Quantitative effect of 4977 bp deletion of mitochondrial DNA on the susceptibility of human cells to UV-induced apoptosis

    Article • Mitochondrion, February 2007, Elsevier

    Professor and Director Yau-Huei Wei

  92. B-group vitamins, MTHFR C677T polymorphism and carotid intima-media thickness in clinically healthy subjects

    Article • European Journal of Clinical Nutrition, January 2007, Springer Science + Business Media

    Professor and Director Yau-Huei Wei

  93. A Common Mitochondrial DNA Variant and Increased Body Mass Index as Associated Factors for Development of Type 2 Diabetes: Additive Effects of Genetic and Environmental Factors

    Article • The Journal of Clinical Endocrinology & Metabolism, January 2007, Endocrine Society

    Professor and Director Yau-Huei Wei

  94. A Follow-up Study in a Taiwanese Family with Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis and Stroke-like Episodes Syndrome

    Article • Journal of the Formosan Medical Association, January 2007, Elsevier

    Professor and Director Yau-Huei Wei

  95. Association of the Y402H Polymorphism in Complement Factor H Gene and Neovascular Age-Related Macular Degeneration in Chinese Patients

    Article • Investigative Ophthalmology & Visual Science, August 2006, Association for Research in Vision and Ophthalmology (ARVO)

    Professor and Director Yau-Huei Wei

  96. Leber's hereditary optic neuropathy: A multifactorial disease

    Article • Progress in Retinal and Eye Research, July 2006, Elsevier

    Professor and Director Yau-Huei Wei

  97. Involvement of protein kinase C delta in the alteration of mitochondrial mass in human cells under oxidative stress

    Article • Free Radical Biology and Medicine, June 2006, Elsevier

    Professor and Director Yau-Huei Wei

  98. Oculopharyngeal somatic myopathy in a patient with a novel large-scale 3399bp deletion and a homoplasmic T5814C transition of the mitochondrial DNA

    Article • Clinical Neurology and Neurosurgery, June 2006, Elsevier

    Professor and Director Yau-Huei Wei

  99. Alteration in the copy number of mitochondrial DNA in leukocytes of patients with mitochondrial encephalomyopathies

    Article • Acta Neurologica Scandinavica, March 2006, Wiley

    Professor and Director Yau-Huei Wei

  100. Visualizing common deletion of mitochondrial DNA-augmented mitochondrial reactive oxygen species generation and apoptosis upon oxidative stress

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, February 2006, Elsevier

    Professor and Director Yau-Huei Wei

  101. Increases of Mitochondrial Mass and Mitochondrial Genome in Association with Enhanced Oxidative Stress in Human Cells Harboring 4,977 BP-Deleted Mitochondrial DNA

    Article • Annals of the New York Academy of Sciences, January 2006, Wiley

    Professor and Director Yau-Huei Wei, Associate Professor Cheng-Yoong Pang, Professor Hsin-Chen Lee

  102. Mitochondrial DNA mutations and mitochondrial DNA depletion in breast cancer

    Article • Genes Chromosomes and Cancer, January 2006, Wiley

    Professor and Director Yau-Huei Wei, Professor Hsin-Chen Lee

  103. INHIBITION OF LUNG CANCER CELL GROWTH BY QUERCETIN GLUCURONIDES VIA G2/M ARREST AND INDUCTION OF APOPTOSIS

    Article • Drug Metabolism and Disposition, November 2005, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor and Director Yau-Huei Wei

  104. Accumulation of mitochondrial DNA with 4977-bp deletion in knee cartilage – an association with idiopathic osteoarthritis

    Article • Osteoarthritis and Cartilage, November 2005, Elsevier

    Professor and Director Yau-Huei Wei, Professor Hsin-Chen Lee

  105. Effects of nitric oxide donors on cybrids harbouring the mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) A3243G mitochondrial DNA mutation

    Article • Biochemical Journal, October 2005, Portland Press Ltd.

    Professor and Director Yau-Huei Wei

  106. Increased oxidative DNA damage, 8-hydroxydeoxy- guanosine, in human pterygium

    Article • Eye, August 2005, Springer Science + Business Media

    Professor and Director Yau-Huei Wei

  107. Mitochondrial DNA Mutation, Oxidative Stress, and Alteration of Gene Expression in Human Aging

    Article • June 2005, Taylor & Francis

    Professor and Director Yau-Huei Wei

  108. Cadmium Toxicity toward Caspase-Independent Apoptosis through the Mitochondria-Calcium Pathway in mtDNA-Depleted Cells

    Article • Annals of the New York Academy of Sciences, May 2005, Wiley

    Professor and Director Yau-Huei Wei

  109. Repeated Ovarian Stimulations Induce Oxidative Damage and Mitochondrial DNA Mutations in Mouse Ovaries

    Article • Annals of the New York Academy of Sciences, May 2005, Wiley

    Professor and Director Yau-Huei Wei

  110. Alteration of the Copy Number of Mitochondrial DNA in Leukocytes of Patients with Hyperlipidemia

    Article • Annals of the New York Academy of Sciences, May 2005, Wiley

    Professor and Director Yau-Huei Wei

  111. Attenuation of UV-Induced Apoptosis by Coenzyme Q10in Human Cells Harboring Large-Scale Deletion of Mitochondrial DNA

    Article • Annals of the New York Academy of Sciences, May 2005, Wiley

    Professor and Director Yau-Huei Wei

  112. Enhanced Generation of Mitochondrial Reactive Oxygen Species in Cybrids Containing 4977-bp Mitochondrial DNA Deletion

    Article • Annals of the New York Academy of Sciences, May 2005, Wiley

    Professor and Director Yau-Huei Wei

  113. High Prevalence of the COII/tRNALysIntergenic 9-bp Deletion in Mitochondrial DNA of Taiwanese Patients with MELAS or MERRF Syndrome

    Article • Annals of the New York Academy of Sciences, May 2005, Wiley

    Professor and Director Yau-Huei Wei, Associate Professor Cheng-Yoong Pang

  114. Increased Oxidative Damage with Altered Antioxidative Status in Type 2 Diabetic Patients Harboring the 16189 T to C Variant of Mitochondrial DNA

    Article • Annals of the New York Academy of Sciences, May 2005, Wiley

    Professor and Director Yau-Huei Wei

  115. Mitochondrial Genome Instability and mtDNA Depletion in Human Cancers

    Article • Annals of the New York Academy of Sciences, May 2005, Wiley

    Professor and Director Yau-Huei Wei, Professor Hsin-Chen Lee

  116. Oxidative Stress-Induced Depolymerization of Microtubules and Alteration of Mitochondrial Mass in Human Cells

    Article • Annals of the New York Academy of Sciences, May 2005, Wiley

    Professor and Director Yau-Huei Wei

  117. Upregulation of Matrix Metalloproteinase 1 and Disruption of Mitochondrial Network in Skin Fibroblasts of Patients with MERRF Syndrome

    Article • Annals of the New York Academy of Sciences, May 2005, Wiley

    Professor and Director Yau-Huei Wei

  118. Differential expression of antioxidant enzymes in various hepatocellular carcinoma cell lines

    Article • Journal of Cellular Biochemistry, January 2005, Wiley

    Professor and Director Yau-Huei Wei

  119. Effects of glycolic acid on the induction of apoptosis via caspase-3 activation in human leukemia cell line (HL-60)

    Article • Food and Chemical Toxicology, November 2004, Elsevier

    Professor and Director Yau-Huei Wei

  120. 8-HYDROXY-2′-DEOXYGUANOSINE IN LEUKOCYTE DNA OF SPERMATIC VEIN AS A BIOMARKER OF OXIDATIVE STRESS IN PATIENTS WITH VARICOCELE

    Article • The Journal of Urology, October 2004, Wolters Kluwer Health

    Professor and Director Yau-Huei Wei

  121. MAGNOLOL ALTERS THE COURSE OF ENDOTOXIN TOLERANCE AND PROVIDES EARLY PROTECTION AGAINST ENDOTOXIN CHALLENGE FOLLOWING SUBLETHAL HEMORRHAGE IN RATS

    Article • Shock, October 2004, Wolters Kluwer Health

    Professor and Director Yau-Huei Wei

  122. Depletion of mitochondrial DNA is a factor of poor quality of human spermatozoa.

    Article • Fertility and Sterility, July 2004, Elsevier

    Professor and Director Yau-Huei Wei

  123. Pulsatile ocular blood flow in patients with Graves' ophthalmopathy

    Article • Eye, June 2004, Nature

    Professor and Director Yau-Huei Wei

  124. Quantification of Plasma Epstein–Barr Virus DNA in Patients with Advanced Nasopharyngeal Carcinoma

    Article • New England Journal of Medicine, June 2004, New England Journal of Medicine (NEJM/MMS)

    Professor and Director Yau-Huei Wei

  125. A prevalent POLG CAG microsatellite length allele in humans and African great apes

    Article • Mammalian Genome, June 2004, Springer Science + Business Media

    Professor Jaume Bertranpetit, Professor and Director Yau-Huei Wei

  126. Increased 8-Hydroxy-2′-Deoxyguanosine in Leukocyte DNA in Leber’s Hereditary Optic Neuropathy

    Article • Investigative Ophthalmology & Visual Science, June 2004, Association for Research in Vision and Ophthalmology (ARVO)

    Professor and Director Yau-Huei Wei

  127. Alteration of the copy number and deletion of mitochondrial DNA in human hepatocellular carcinoma

    Article • British Journal of Cancer, May 2004, Springer Science + Business Media

    Professor and Director Yau-Huei Wei, Professor Hsin-Chen Lee

  128. Prenatal diagnosis of a fetus harboring an intermediate load of the A3243G mtDNA mutation in a maternal carrier diagnosed with MELAS syndrome

    Article • Prenatal Diagnosis, May 2004, Wiley

    Professor and Director Yau-Huei Wei

  129. Association of the Mitochondrial DNA 16189 T to C Variant with Lacunar Cerebral Infarction: Evidence from a Hospital-Based Case-Control Study

    Article • Annals of the New York Academy of Sciences, April 2004, Wiley

    Professor and Director Yau-Huei Wei

  130. Mitochondrial DNA 4,977-bp Deletion in Paired Oral Cancer and Precancerous Lesions Revealed by Laser Microdissection and Real-Time Quantitative PCR

    Article • Annals of the New York Academy of Sciences, April 2004, Wiley

    Professor and Director Yau-Huei Wei

  131. Mitochondrial DNA Mutation and Depletion Increase the Susceptibility of Human Cells to Apoptosis

    Article • Annals of the New York Academy of Sciences, April 2004, Wiley

    Professor and Director Yau-Huei Wei

  132. Somatic mutations in the D-loop and decrease in the copy number of mitochondrial DNA in human hepatocellular carcinoma

    Article • Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, March 2004, Elsevier

    Professor and Director Yau-Huei Wei, Professor Hsin-Chen Lee

  133. Genetic polymorphism of hOGG1 and risk of pterygium in Chinese

    Article • Eye, January 2004, Springer Science + Business Media

    Professor and Director Yau-Huei Wei

  134. Mitochondrial DNA mutations can cause many human diseases.

    Article • January 2004, Springer Science + Business Media

    Professor and Director Yau-Huei Wei

  135. Mediating of caspase-independent apoptosis by cadmium through the mitochondria-ROS pathway in MRC-5 fibroblasts

    Article • Journal of Cellular Biochemistry, January 2004, Wiley

    Professor and Director Yau-Huei Wei

  136. Mitochondrial DNA Mutation and Depletion Increase the Susceptibility of Human Cells to Apoptosis

    Article • January 2004, Springer Science + Business Media

    Professor and Director Yau-Huei Wei

  137. Increased expression of manganese-superoxide dismutase in fibroblasts of patients with CPEO syndrome

    Article • Molecular Genetics and Metabolism, November 2003, Elsevier

    Professor and Director Yau-Huei Wei, Professor Hsin-Chen Lee

  138. Oxidative damage to mitochondrial DNA in atrial muscle of patients with atrial fibrillation

    Article • Free Radical Biology and Medicine, November 2003, Elsevier

    Professor and Director Yau-Huei Wei

  139. Clinical Research. Genetic analysis in Leber's hereditary optic neuropathy using the comparative genomic hybridization technique

    Article • Clinical and Experimental Ophthalmology, October 2003, Wiley

    Professor and Director Yau-Huei Wei

  140. Mitochondria-mediated caspase-independent apoptosis induced by cadmium in normal human lung cells

    Article • Journal of Cellular Biochemistry, April 2003, Wiley

    Professor and Director Yau-Huei Wei

  141. Oxidative-stress-related changes in the livers of bile-duct-ligated rats

    Article • Journal of Biomedical Science, March 2003, Springer Science + Business Media

    Professor and Director Yau-Huei Wei

  142. Early prediction of response to intravenous iron supplementation by reticulocyte haemoglobin content and high-fluorescence reticulocyte count in haemodialysis patients

    Article • Nephrology Dialysis Transplantation, February 2003, Oxford University Press (OUP)

    Professor and Director Yau-Huei Wei

  143. Mitochondrial DNA mutations and oxidative stress in mitochondrial diseases

    Article • January 2003, Elsevier

    Professor and Director Yau-Huei Wei, Professor Hsin-Chen Lee

  144. Oxidative Stress, Mitochondrial DNA Mutation, and Impairment of Antioxidant Enzymes in Aging

    Article • Experimental Biology and Medicine, October 2002, SAGE Publications

    Professor and Director Yau-Huei Wei, Professor Hsin-Chen Lee

  145. Increase of mitochondrial DNA in blood cells of patients with Leber's hereditary optic neuropathy with 11778 mutation

    Article • British Journal of Ophthalmology, September 2002, BMJ

    Professor and Director Yau-Huei Wei

  146. Clinical phenotype, prognosis and mitochondrial DNA mutation load in mitochondrial encephalomyopathies

    Article • Journal of Biomedical Science, September 2002, Springer Science + Business Media

    Professor and Director Yau-Huei Wei

  147. Mitochondrial DNA mutations and oxidative damage in skeletal muscle of patients with chronic uremia

    Article • Journal of Biomedical Science, September 2002, Springer Science + Business Media

    Professor and Director Yau-Huei Wei

  148. PCR detection of circulating tumor cells in nasopharyngeal carcinoma patients with distant metastasis: Effect of enzyme and sampling

    Article • Head & Neck, May 2002, Wiley

    Professor and Director Yau-Huei Wei

  149. Multiple rearrangements of mitochondrial DNA in unfertilized human oocytes

    Article • Fertility and Sterility, May 2002, Elsevier

    Professor and Director Yau-Huei Wei

  150. Increased Oxidative Damage to Peripheral Blood Leukocyte DNA in Chronic Peritoneal Dialysis Patients

    Article • Journal of the American Society of Nephrology, May 2002, American Society of Nephrology

    Professor and Director Yau-Huei Wei

  151. Detection of DNA mutations associated with mitochondrial diseases by Agilent 2100 bioanalyzer

    Article • Clinica Chimica Acta, April 2002, Elsevier

    Professor and Director Yau-Huei Wei

  152. Polymorphisms of glutathione S-transferase M1 and male infertility in Taiwanese patients with varicocele

    Article • Human Reproduction, March 2002, Oxford University Press (OUP)

    Professor and Director Yau-Huei Wei

  153. Leber's Hereditary Optic Neuropathy—The Spectrum of Mitochondrial DNA Mutations in Chinese Patients

    Article • Japanese Journal of Ophthalmology, February 2002, Elsevier

    Professor and Director Yau-Huei Wei

  154. Evaluation of cytokeratin-19 mRNA as a tumor marker in the peripheral blood of nasopharyngeal carcinoma patients receiving concurrent chemoradiotherapy

    Article • International Journal of Cancer, January 2002, Wiley

    Professor and Director Yau-Huei Wei

  155. Antioxidant and Anticonvulsant Effect of a Modified Formula of Chaihu-Longu-Muli-Tang

    Article • The American Journal of Chinese Medicine, January 2002, World Scientific Pub Co Pte Lt

    Professor and Director Yau-Huei Wei

  156. Wernicke’s Encephalopathy in a Patient with Multiple Symmetrical Lipomatosis and the A8344G Mutation of Mitochondrial DNA

    Article • European Neurology, January 2002, Karger Publishers

    Professor and Director Yau-Huei Wei, Professor Hsin-Chen Lee

  157. Enhanced oxidative damage in human cells harboring A3243G mutation of mitochondrial DNA: implication of oxidative stress in the pathogenesis of mitochondrial diabetes

    Article • Diabetes Research and Clinical Practice, December 2001, Elsevier

    Professor and Director Yau-Huei Wei, Associate Professor Cheng-Yoong Pang, Professor Hsin-Chen Lee

  158. Molecular analysis of diabetes mellitus-associated A3243G mitochondrial DNA mutation in Taiwanese cases

    Article • Diabetes Research and Clinical Practice, December 2001, Elsevier

    Professor and Director Yau-Huei Wei

  159. Mutations at the mitochondrial DNA polymerase (POLG) locus associated with male infertility

    Article • Nature Genetics, October 2001, Springer Science + Business Media

    Professor and Director Yau-Huei Wei

  160. A novel mutation in the mitochondrial 16S rRNA gene in a patient with MELAS syndrome, diabetes mellitus, hyperthyroidism and cardiomyopathy

    Article • Journal of Biomedical Science, July 2001, Springer Science + Business Media

    Professor and Director Yau-Huei Wei, Associate Professor Cheng-Yoong Pang

  161. Erythropoietin and iron: the role of ascorbic acid

    Article • Nephrology Dialysis Transplantation, July 2001, Oxford University Press (OUP)

    Professor and Director Yau-Huei Wei

  162. Oxidative damage to proteins and decrease of antioxidant capacity in patients with varicocele

    Article • Free Radical Biology and Medicine, June 2001, Elsevier

    Professor and Director Yau-Huei Wei

  163. Accumulation of mitochondrial DNA deletions in human oral tissues — effects of betel quid chewing and oral cancer

    Article • Mutation Research/Genetic Toxicology and Environmental Mutagenesis, June 2001, Elsevier

    Professor and Director Yau-Huei Wei, Professor Hsin-Chen Lee

  164. Detection of Epstein-Barr Virus DNA in the Peripheral-Blood Cells of Patients With Nasopharyngeal Carcinoma: Relationship to Distant Metastasis and Survival

    Article • Journal of Clinical Oncology, May 2001, American Society of Clinical Oncology (ASCO)

    Professor and Director Yau-Huei Wei

  165. Biomarkers of DNA damage in patients with end‐stage renal disease: mitochondrial DNA mutation in hair follicles

    Article • Nephrology Dialysis Transplantation, March 2001, Oxford University Press (OUP)

    Professor and Director Yau-Huei Wei

  166. Involvement of nervous system in maternally inherited diabetes and deafness (MIDD) with the A3243G mutation of mitochondrial DNA

    Article • Acta Neurologica Scandinavica, March 2001, Wiley

    Professor and Director Yau-Huei Wei, Professor Hsin-Chen Lee

  167. Article • Biogerontology, January 2001, Springer Science + Business Media

    Professor and Director Yau-Huei Wei, Professor Hsin-Chen Lee

  168. 8-Hydroxy-2′-Deoxyguanosine of leukocyte DNA as a marker of oxidative stress in chronic hemodialysis patients

    Article • American Journal of Kidney Diseases, November 2000, Elsevier

    Professor Der-Cherng Tarng, Professor and Director Yau-Huei Wei

  169. Large-scale mitochondrial DNA deletions in skeletal muscle of patients with end-stage renal disease

    Article • Free Radical Biology and Medicine, September 2000, Elsevier

    Professor and Director Yau-Huei Wei

  170. Effect of vitamin E-bonded membrane on the 8-hydroxy 2′-deoxyguanosine level in leukocyte DNA of hemodialysis patients

    Article • Kidney International, August 2000, Elsevier

    Professor Der-Cherng Tarng, Professor and Director Yau-Huei Wei

  171. Autoantibody against oxidized low-density lipoproteins may be enhanced by cigarette smoking

    Article • Chemico-Biological Interactions, July 2000, Elsevier

    Professor and Director Yau-Huei Wei

  172. Increase of mitochondria and mitochondrial DNA in response to oxidative stress in human cells

    Article • Biochemical Journal, June 2000, Portland Press Ltd.

    Professor and Director Yau-Huei Wei, Professor Hsin-Chen Lee

  173. Increase of mitochondria and mitochondrial DNA in response to oxidative stress in human cells

    Article • Biochemical Journal, June 2000, Portland Press Ltd.

    Professor and Director Yau-Huei Wei, Professor Hsin-Chen Lee

  174. Mitochondrial DNA deletion of the human detrusor after partial bladder outlet obstruction—correlation with urodynamic analysis

    Article • Urology, April 2000, Elsevier

    Professor and Director Yau-Huei Wei

  175. Lipophilic Antioxidants and Iron Status in ESRD Patients on Hemodialysis

    Article • January 2000, Karger Publishers

    Professor and Director Yau-Huei Wei

  176. Interferon-α2a effects on complement activation and regulation in MS patients

    Article • Acta Neurologica Scandinavica, January 2000, Wiley

    Professor and Director Yau-Huei Wei, Associate Professor Cheng-Yoong Pang

  177. MORPHOLOGICAL AND MORPHOMETRIC ANALYSIS OF HUMAN DETRUSOR MITOCHONDRIA WITH URODYNAMIC CORRELATION AFTER PARTIAL BLADDER OUTLET OBSTRUCTION

    Article • The Journal of Urology, January 2000, Wolters Kluwer Health

    Professor and Director Yau-Huei Wei

  178. Mitochondrial role in life and death of the cell

    Article • Journal of Biomedical Science, January 2000, Springer Science + Business Media

    Professor and Director Yau-Huei Wei, Professor Hsin-Chen Lee

  179. Correction of Pancreatic β-Cell Dysfunction with Coenzyme Q10 in a Patient with Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-Like Episodes Syndrome and Diabetes mellitus

    Article • European Neurology, January 2000, Karger Publishers

    Professor and Director Yau-Huei Wei

  180. Enhanced oxidative stress in haemodialysis patients receiving intravenous iron therapy

    Article • Nephrology Dialysis Transplantation, November 1999, Oxford University Press (OUP)

    Professor and Director Yau-Huei Wei

  181. Intravenous ascorbic acid as an adjuvant therapy for recombinant erythropoietin in hemodialysis patients with hyperferritinemia

    Article • Kidney International, June 1999, Elsevier

    Professor Der-Cherng Tarng, Professor and Director Yau-Huei Wei

  182. Quantitation and origin of the mitochondrial membrane potential in human cells lacking mitochondrial DNA

    Article • European Journal of Biochemistry, May 1999, Wiley

    Professor and Director Yau-Huei Wei

  183. Exclusive Homoplasmic 11778 Mutation in Mitochondrial DNA of Chinese Patients With Leber's Hereditary Optic Neuropathy

    Article • Japanese Journal of Ophthalmology, May 1999, Elsevier

    Professor and Director Yau-Huei Wei, Professor Hsin-Chen Lee

  184. Tissue mosaicism in the skeletal muscle and sural nerve biopsies in the MELAS syndrome

    Article • Acta Neurologica Scandinavica, February 1999, Wiley

    Professor and Director Yau-Huei Wei, Associate Professor Cheng-Yoong Pang

  185. Concurrent Increase of Oxidative DNA Damage and Lipid Peroxidation Together with Mitochondrial DNA Mutation in Human Lung Tissues During Aging—Smoking Enhances Oxidative Stress on the Aged Tissues

    Article • Archives of Biochemistry and Biophysics, February 1999, Elsevier

    Professor and Director Yau-Huei Wei, Professor Hsin-Chen Lee

  186. Decreased ATP synthesis is phenotypically expressed during increased energy demand in fibroblasts containing mitochondrial tRNA mutations

    Article • European Journal of Biochemistry, January 1999, Wiley

    Professor and Director Yau-Huei Wei

  187. Age-Associated Alteration of Blood Thiol-Group-Related Antioxidants in Smokers

    Article • Environmental Research, January 1999, Elsevier

    Professor and Director Yau-Huei Wei

  188. Oxidative damage elicited by imbalance of free radical scavenging enzymes is associated with large-scale mtDNA deletions in aging human skin

    Article • Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, January 1999, Elsevier

    Professor and Director Yau-Huei Wei, Professor Hsin-Chen Lee

  189. Human lung accumulates mitochondrial DNA mutations in aging and in smokers.

    Article • FEBS Letters, December 1998, Wiley

    Professor and Director Yau-Huei Wei, Professor Hsin-Chen Lee

  190. The paper contends that mtDNA mutations accumulate in aging human tissues.

    Article • Trends in Genetics, December 1998, Elsevier

    Professor and Director Yau-Huei Wei

  191. Smoking-Associated Mitochondrial DNA Mutations and Lipid Peroxidation in Human Lung Tissues

    Article • American Journal of Respiratory Cell and Molecular Biology, December 1998, American Thoracic Society

    Professor and Director Yau-Huei Wei

  192. Alterations of small-molecular-weight antioxidants in the blood of smokers

    Article • Chemico-Biological Interactions, November 1998, Elsevier

    Professor and Director Yau-Huei Wei

  193. Oxidative Damage and Mutation to Mitochondrial DNA and Age-dependent Decline of Mitochondrial Respiratory Functiona

    Article • Annals of the New York Academy of Sciences, November 1998, Wiley

    Professor and Director Yau-Huei Wei, Associate Professor Cheng-Yoong Pang, Professor Hsin-Chen Lee

  194. Bioenergetic consequences of accumulating the common 4977-bp mitochondrial DNA deletion

    Article • European Journal of Biochemistry, October 1998, Wiley

    Professor and Director Yau-Huei Wei, Associate Professor Cheng-Yoong Pang

  195. Multiple deletions of mitochondrial DNA are associated with the decline of motility and fertility of human spermatozoa

    Article • Molecular Human Reproduction, July 1998, Oxford University Press (OUP)

    Professor and Director Yau-Huei Wei

  196. AT-rich sequences flanking the 5′-end breakpoint of the 4977-bp deletion of human mitochondrial DNA are located between two bent-inducing DNA sequences that assume distorted structure in organello

    Article • Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, July 1998, Elsevier

    Professor and Director Yau-Huei Wei

  197. Independent occurrence of somatic mutations in mitochondrial DNA of human skin from subjects of various ages

    Article • Human Mutation, January 1998, Wiley

    Professor and Director Yau-Huei Wei, Associate Professor Cheng-Yoong Pang, Professor Hsin-Chen Lee

  198. Oxidative Stress and Mitochondrial DNA Mutations in Human Aging

    Article • Experimental Biology and Medicine, January 1998, SAGE Publications

    Professor and Director Yau-Huei Wei

  199. Role of mitochondria in human aging

    Article • Journal of Biomedical Science, November 1997, Springer Science + Business Media

    Professor and Director Yau-Huei Wei, Professor Hsin-Chen Lee

  200. In vitro and in vivo protective effect of honokiol on rat liver from peroxidative injury

    Article • Life Sciences, October 1997, Elsevier

    Professor and Director Yau-Huei Wei

  201. Prevalence of apolipoprotein E genotypes in ischaemic cerebrovascular disease in end-stage renal disease patients

    Article • Nephrology Dialysis Transplantation, September 1997, Oxford University Press (OUP)

    Professor and Director Yau-Huei Wei

  202. Phenytoin-mediated oxidative stress in serum of female epileptics: A possible pathogenesis in the fetal hydantoin syndrome

    Article • Human & Experimental Toxicology, March 1997, SAGE Publications

    Professor and Director Yau-Huei Wei

  203. Smoking-associated mitochondrial DNA mutations in human hair follicles

    Article • Environmental and Molecular Mutagenesis, January 1997, Wiley

    Professor and Director Yau-Huei Wei

  204. Peripheral Neuropathy in Mitochondrial Encephalomyopathies

    Article • European Neurology, January 1997, Karger Publishers

    Professor and Director Yau-Huei Wei, Associate Professor Cheng-Yoong Pang

  205. Leigh syndrome associated with mitochondrial DNA 8993 T → G mutation and ragged-red fibers

    Article • Pediatric Neurology, July 1996, Elsevier

    Professor and Director Yau-Huei Wei, Associate Professor Cheng-Yoong Pang

  206. Simultaneous Increase of Mitochondrial DNA Deletions and Lipid Peroxidation in Human Aging

    Article • Annals of the New York Academy of Sciences, June 1996, Wiley

    Professor and Director Yau-Huei Wei, Professor Hsin-Chen Lee

  207. Tissue distribution of mutant mitochondrial DNA in a patient with MERRF syndrome

    Article • Muscle & Nerve, April 1996, Wiley

    Professor and Director Yau-Huei Wei, Associate Professor Cheng-Yoong Pang

  208. Compensatory elevation of complex II activity in Leber's hereditary optic neuropathy.

    Article • British Journal of Ophthalmology, January 1996, BMJ

    Professor and Director Yau-Huei Wei, Associate Professor Cheng-Yoong Pang, Professor Hsin-Chen Lee

  209. Defective mitochondrial oxidative phosphorylation in varicocele-bearinc testicles

    Article • Urology, October 1995, Elsevier

    Professor and Director Yau-Huei Wei

  210. The 4977 bp deletion of mitochondrial DNA may contribute to diminished human sperm fertility.

    Article • Biology of Reproduction, April 1995, Oxford University Press (OUP)

    Professor and Director Yau-Huei Wei

  211. Human Skin Mitochondrial DNA Deletions Associated with Light Exposure

    Article • Archives of Biochemistry and Biophysics, August 1994, Elsevier

    Professor and Director Yau-Huei Wei, Associate Professor Cheng-Yoong Pang, Professor Hsin-Chen Lee

  212. A specific 4977-bp deletion of mitochondrial DNA in human ageing skin

    Article • Archives of Dermatological Research, August 1994, Springer Science + Business Media

    Professor and Director Yau-Huei Wei, Professor Hsin-Chen Lee

  213. MELAS syndrome with mitochondrial tRNA(Leu(UUR)) gene mutation in a Chinese family.

    Article • Journal of Neurology Neurosurgery & Psychiatry, May 1994, BMJ

    Professor and Director Yau-Huei Wei, Associate Professor Cheng-Yoong Pang, Professor Hsin-Chen Lee

  214. Differential accumulations of 4,977 bp deletion in mitochondrial DNA of various tissues in human ageing

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, April 1994, Elsevier

    Professor and Director Yau-Huei Wei, Associate Professor Cheng-Yoong Pang, Professor Hsin-Chen Lee

  215. Age-dependent increase of mitochondrial DNA deletions together with lipid peroxides and superoxide dismutase in human liver mitochondria

    Article • Free Radical Biology and Medicine, February 1994, Elsevier

    Professor and Director Yau-Huei Wei, Professor Hsin-Chen Lee

  216. Astragalus Membranaceus and Polygonum Multijlorum Protect Rat Heart Mitochondria Against Lipid Peroxidation

    Article • The American Journal of Chinese Medicine, January 1994, World Scientific Pub Co Pte Lt

    Professor and Director Yau-Huei Wei

  217. Ophthalmologic Manifestations in MELAS Syndrome

    Article • Archives of Neurology, September 1993, American Medical Association (AMA)

    Professor and Director Yau-Huei Wei, Associate Professor Cheng-Yoong Pang

  218. Our team discovered that mitochondrial DNA mutations accumulate in human aging tissues.

    Article • Mutation Research/DNAging, September 1992, Elsevier

    Professor and Director Yau-Huei Wei

  219. Production of cellulolytic enzymes from theXylaria andHypoxylon species of xylariaceae

    Article • World Journal of Microbiology and Biotechnology, March 1992, Springer Science + Business Media

    Professor and Director Yau-Huei Wei

  220. Ageing-associated 5 kb deletion in human liver mitochondrial DNA

    Article • Biochemical and Biophysical Research Communications, July 1991, Elsevier

    Professor and Director Yau-Huei Wei

  221. Human Follicular Fluid Stimulates the Motility of Washed Human Sperm

    Article • Archives of Andrology, January 1991, Taylor & Francis

    Professor and Director Yau-Huei Wei

  222. Effect of Emitted Bioenergy on Biochemical Functions of Cells

    Article • The American Journal of Chinese Medicine, January 1991, World Scientific Pub Co Pte Lt

    Professor and Director Yau-Huei Wei

  223. Immobilized enzyme system for determination of sialic acid in serum or urine

    Article • Enzyme and Microbial Technology, January 1991, Elsevier

    Professor and Director Yau-Huei Wei

  224. Liver mitochondrial respiratory functions decline with age

    Article • Biochemical and Biophysical Research Communications, December 1989, Elsevier

    Professor and Director Yau-Huei Wei

  225. Comparative Study on Biochemical Effects of Alcohols on Rat Liver Mitochondrial Respiration and Oxidative Phosphorylation

    Article • January 1989, Springer Science + Business Media

    Professor and Director Yau-Huei Wei

  226. Stabilized ubisemiquinone in reconstituted succinate ubiquinone reductase

    Article • Biochemical and Biophysical Research Communications, April 1987, Elsevier

    Professor and Director Yau-Huei Wei

  227. Biochemical Characterization of Boar Sperm Cytochrome Oxidase

    Article • January 1987, Springer Science + Business Media

    Professor and Director Yau-Huei Wei

  228. Isolation, purification, and properties of boar sperm cytochrome oxidase

    Article • Journal of Protein Chemistry, June 1986, Springer Science + Business Media

    Professor and Director Yau-Huei Wei

  229. The inhibitory effect of some ionophores on human sperm motility

    Article • Contraception, March 1986, Elsevier

    Professor and Director Yau-Huei Wei

  230. Inhibitory effect in vitro of PR toxin, a mycotoxin from Penicillium roqueforti, on the mitochondrial HCO3−-ATPase of the rat brain, heart and kidney

    Article • Toxicon, January 1986, Elsevier

    Professor and Director Yau-Huei Wei

  231. Effect of ochratoxin A on rat liver mitochondrial respiration and oxidative phosphorylation

    Article • Toxicology, August 1985, Elsevier

    Professor and Director Yau-Huei Wei

  232. Involvement of calcium in the caffeine stimulation of human sperm motility.

    Article • British Journal of Clinical Pharmacology, June 1985, Wiley

    Professor and Director Yau-Huei Wei

  233. Inhibition of the mitochondrial Mg2+-ATPase by propranolol

    Article • Biochemical Pharmacology, April 1985, Elsevier

    Professor and Director Yau-Huei Wei

  234. Activities of Transport Adenosine Triphosphatases in Erythrocyte Membranes of Healthy and Hypertensive Subjects

    Article • Clinical and Experimental Hypertension Part A Theory and Practice, January 1985, Taylor & Francis

    Professor and Director Yau-Huei Wei

  235. Calcium antagonists stimulate sperm motility in ejaculated human semen.

    Article • British Journal of Clinical Pharmacology, January 1985, Wiley

    Professor and Director Yau-Huei Wei

  236. CALCIUM CHELATORS STIMULATE SPERM MOTILITY IN EJACULATED HUMAN SEMEN

    Article • The Lancet, February 1984, Elsevier

    Professor and Director Yau-Huei Wei

  237. Electron paramagnetic resonance- (EPR-) resolved kinetics of cryogenic nitric oxide recombination to cytochrome c oxidase and myoglobin

    Article • Biophysical Journal, February 1984, Elsevier

    Professor and Director Yau-Huei Wei

  238. Mitochondrial respiration inhibitors and human sperm motility: implication in the development of spermicides.

    Article • British Journal of Clinical Pharmacology, November 1983, Wiley

    Professor and Director Yau-Huei Wei

  239. ChemInform Abstract: RESONANCE RAMAN AND ELECTRONIC SPECTRA OF HEME A COMPLEXES AND CYTOCHROME OXIDASE

    Article • Chemischer Informationsdienst, September 1983, Wiley

    Professor and Director Yau-Huei Wei

  240. Amino acid sequence of bovine heart cytochrome oxidase subunit IV (Albany)

    Article • Biochemical and Biophysical Research Communications, January 1983, Elsevier

    Professor and Director Yau-Huei Wei

  241. Effect of Phospholipid on EPR Visible Copper Signal of Cytochrome Oxidase

    Article • January 1982, Elsevier

    Professor and Director Yau-Huei Wei

  242. Epr and Endor of NO-Ligated Cytochrome c Oxidase

    Article • January 1982, Springer Science + Business Media

    Professor and Director Yau-Huei Wei

  243. The effect of phospholipid depletion on the EPR behavior of cytochrome oxidase

    Article • Archives of Biochemistry and Biophysics, September 1981, Elsevier

    Professor and Director Yau-Huei Wei

  244. Ubisemiquinone radicals from the cytochrome b−c1 complex of the mitochondrial electron transport chain—Demonstration of QP-S radical formation

    Article • Biochemical and Biophysical Research Communications, April 1981, Elsevier

    Professor and Director Yau-Huei Wei

  245. Electron nuclear double resonance of cytochrome oxidase: Nitrogen and proton endor from the ‘copper’ EPR signal

    Article • Biochimica et Biophysica Acta (BBA) - Protein Structure, December 1978, Elsevier

    Professor and Director Yau-Huei Wei

  246. ELECTRON NUCLEAR DOUBLE RESONANCE OF CYTOCHROME OXIDASE

    Article • January 1978, Elsevier

    Professor and Director Yau-Huei Wei

  247. Amino acid sequence of the heme a subunit of bovine heart cytochrome oxidase and sequence homology with hemoglobin

    Article • Biochemical and Biophysical Research Communications, June 1977, Elsevier

    Professor and Director Yau-Huei Wei