All Stories

  1. Integrated stress response-upregulated mitochondrial SLC1A5var enhances glucose dependency in human breast cancer cells in vitro
  2. Mitochondrial dysfunction decreases cisplatin sensitivity in gastric cancer cells through upregulation of integrated stress response and mitokine GDF15
  3. Role of mitochondrial alterations in human cancer progression and cancer immunity
  4. Growth differentiation factor 15 induces cisplatin resistance through upregulation of xCT expression and glutathione synthesis in gastric cancer
  5. The Clinical Benefits of Antiresorptive Agents in Patients with Primary Breast Cancer Receiving Adjuvant Endocrine Therapy: A Systematic Review with Pairwise and Network Meta-analysis
  6. Effect of co‐medications and potential risk factors of high‐dose methotrexate‐mediated acute hepatotoxicity in patients with osteosarcoma
  7. Cardiovascular Medication Use and Risk of Acute Exacerbation in Patients With Asthma-COPD Overlap (CVACO Study)
  8. Mitochondrial stress adaptation promotes resistance to aromatase inhibitor in human breast cancer cells via ROS/calcium up-regulated amphiregulin–estrogen receptor loop signaling
  9. Salubrinal Enhances Cancer Cell Death during Glucose Deprivation through the Upregulation of xCT and Mitochondrial Oxidative Stress
  10. Significance of Kynurenine 3-Monooxygenase Expression in Colorectal Cancer
  11. Circulating microRNAs Associated With Reversible Cerebral Vasoconstriction Syndrome
  12. DNAJA3/Tid1 Is Required for Mitochondrial DNA Maintenance and Regulates Migration and Invasion of Human Gastric Cancer Cells
  13. Prevalence of mitochondrial DNA common deletion in patients with gliomas and meningiomas: A first report from a Malaysian study group
  14. Combination of peroxisome proliferator–activated receptor gamma and retinoid X receptor agonists induces sodium/iodide symporter expression and inhibits cell growth of human thyroid cancer cells
  15. ROS Mediate xCT-Dependent Cell Death in Human Breast Cancer Cells under Glucose Deprivation
  16. Mevalonate Pathway Enzyme HMGCS1 Contributes to Gastric Cancer Progression
  17. Role of the mitochondrial stress response in human cancer progression
  18. Kynurenine 3-monooxygenase upregulates pluripotent genes through β-catenin and promotes triple-negative breast cancer progression
  19. Ash2l interacts with Oct4-stemness circuitry to promote super-enhancer-driven pluripotency network
  20. Printing a Three‐Dimensional Patient‐Specific Safety Device for Reducing the Potential Risk of Mental Nerve Injury During Transoral Thyroidectomy
  21. Mucolytic Agents and Statins Use is Associated with a Lower Risk of Acute Exacerbations in Patients with Bronchiectasis-Chronic Obstructive Pulmonary Disease Overlap
  22. Activated Integrated Stress Response Induced by Salubrinal Promotes Cisplatin Resistance in Human Gastric Cancer Cells via Enhanced xCT Expression and Glutathione Biosynthesis
  23. Generation of two isogenic human induced pluripotent stem cell lines from a 15 year-old female patient with MERRF syndrome and A8344G mutation of mitochondrial DNA
  24. MicroRNA‑23a/27a/24‑2 cluster promotes gastric cancer cell proliferation synergistically
  25. Correlation between HGF/c-Met and Notch1 signaling pathways in human gastric cancer cells
  26. Bioactivity and gene expression profiles of hiPSC-generated retinal ganglion cells in MT-ND4 mutated Leber's hereditary optic neuropathy
  27. CHAC1 degradation of glutathione enhances cystine-starvation-induced necroptosis and ferroptosis in human triple negative breast cancer cells via the GCN2-eIF2α-ATF4 pathway
  28. MAOA-a novel decision maker of apoptosis and autophagy in hormone refractory neuroendocrine prostate cancer cells
  29. REST is a crucial regulator for acquiring EMT-like and stemness phenotypes in hormone-refractory prostate cancer
  30. Notch1-promoted TRPA1 expression in erythroleukemic cells suppresses erythroid but enhances megakaryocyte differentiation
  31. ROS and Oxidative Stress in Stem Cells
  32. miR-151-3p Targets TWIST1 to Repress Migration of Human Breast Cancer Cells
  33. Mitochondrial dysfunction enhances cisplatin resistance in human gastric cancer cells via the ROS-activated GCN2-eIF2α-ATF4-xCT pathway
  34. Combined effect of honokiol and rosiglitazone on cell growth inhibition through enhanced G0/G1 phase arrest in hepatoma cells
  35. Peroxisome Proliferator-Activated Receptor γ Expression Is Inversely Associated with Macroscopic Vascular Invasion in Human Hepatocellular Carcinoma
  36. Notch1 pathway-mediated microRNA-151-5p promotes gastric cancer progression
  37. Impaired ROS Scavenging System in Human Induced Pluripotent Stem Cells Generated from Patients with MERRF Syndrome
  38. Role of mitochondrial dysfunction in cancer progression
  39. Dysregulation of Mitochondrial Functions and Osteogenic Differentiation in Cisd2-Deficient Murine Induced Pluripotent Stem Cells
  40. Functional dysconnection in the prefrontal–amygdala circuitry in unaffected siblings of patients with bipolar I disorder
  41. Energy metabolism determines the sensitivity of human hepatocellular carcinoma cells to mitochondrial inhibitors and biguanide drugs
  42. The reciprocal regulation loop of Notch2 pathway and miR-23b in controlling gastric carcinogenesis
  43. Krüppel-like factor 4 modulates the migration and invasion of hepatoma cells by suppressing TIMP-1 and TIMP-2
  44. Peripheral and central glucose utilizations modulated by mitochondrial DNA 10398A in bipolar disorder
  45. Targeting Aerobic Glycolysis and HIF-1α Expression Enhance Imiquimod-induced Apoptosis in Cancer Cells
  46. Somatic alterations in mitochondrial DNA and mitochondrial dysfunction in gastric cancer progression
  47. SIRT3 Expression as a Biomarker for Better Prognosis in Gastric Cancer
  48. Mitochondrial dysfunction represses HIF-1α protein synthesis through AMPK activation in human hepatoma HepG2 cells
  49. Downregulation of tumor suppressor MBP-1 by microRNA-363 in gastric carcinogenesis
  50. 7-Ketocholesterol induces P-glycoprotein through PI3K/mTOR signaling in hepatoma cells
  51. Mitochondrial DNA alterations and mitochondrial dysfunction in the progression of hepatocellular carcinoma
  52. Regulation of mitochondrial FoF1ATPase activity by Sirt3-catalyzed deacetylation and its deficiency in human cells harboring 4977bp deletion of mitochondrial DNA
  53. Norcantharidin suppresses cell growth and migration with enhanced anticancer activity of gefitinib and cisplatin in human non-small cell lung cancer cells
  54. Suppressor of cytokine signaling 6 (SOCS6) promotes mitochondrial fission via regulating DRP1 translocation
  55. Mitochondrial dysfunction promotes cell migration via reactive oxygen species-enhanced β5-integrin expression in human gastric cancer SC-M1 cells
  56. A novel mechanism of coenzyme Q10 protects against human endothelial cells from oxidative stress-induced injury by modulating NO-related pathways
  57. Curcumin induces the apoptosis of human monocytic leukemia THP-1 cells via the activation of JNK/ERK Pathways
  58. Targeting Protective Autophagy Exacerbates UV-Triggered Apoptotic Cell Death
  59. Melatonin attenuates kainic acid‐induced neurotoxicity in mouse hippocampus via inhibition of autophagy and α‐synuclein aggregation
  60. Mitochondria and Aging
  61. Enhanced Differentiation of Three-Gene-Reprogrammed Induced Pluripotent Stem Cells into Adipocytes via Adenoviral-Mediated PGC-1α Overexpression
  62. Ascorbic acid mitigates the myocardial injury after cardiac arrest and electrical shock
  63. Gene expression profiling of peripheral blood leukocytes identifies and validates ABCB1 as a novel biomarker for Alzheimer's disease
  64. Somatic mutations of the mitochondrial genome in human breast cancers
  65. Autophagy inhibition enhances apoptosis triggered by BO-1051, an N-mustard derivative, and involves the ATM signaling pathway
  66. PGC-1α Mediates Differentiation of Mesenchymal Stem Cells to Brown Adipose Cells
  67. Somatic mutations of mitochondrial DNA in aging and cancer progression
  68. Role of autophagy in protection afforded by hypoxic preconditioning against MPP+-induced neurotoxicity in SH-SY5Y cells
  69. Mitochondrial DNA Content as a Potential Marker to Predict Response to Anthracycline in Breast Cancer Patients
  70. Gly482Ser polymorphism in the peroxisome proliferator–activated receptor γ coactivator–1α gene is associated with oxidative stress and abdominal obesity
  71. Somatic mutations of mitochondrial genome in hepatocellular carcinoma
  72. Somatic mutations in mitochondrial genome and their potential roles in the progression of human gastric cancer
  73. Heteroplasmy of Mitochondrial D310 Mononucleotide Repeat Region in the Blood of Patients with Alzheimer's Disease
  74. Association between mitochondrial DNA 4,977 bp deletion and NAD(P)H:quinone oxidoreductase 1 C609T polymorphism in human breast tissues
  75. Mitochondrial dysfunction-induced amphiregulin upregulation mediates chemo-resistance and cell migration in HepG2 cells
  76. Mitochondrial DNA Instability and Metabolic Shift in Human Cancers
  77. MELAS syndrome associated with a tandem duplication in the D-loop of mitochondrial DNA
  78. CPEO and carnitine deficiency overlapping in MELAS syndrome
  79. Type IV hyperlipoproteinemia and moderate instability of CAG triplet expansion in the androgen-receptor gene
  80. MELAS syndrome: correlation between clinical features and molecular genetic analysis
  81. Peripheral blood mitochondrial DNA content and dysregulation of glucose metabolism
  82. Involvement of oxidative stress-activated JNK signaling in the methamphetamine-induced cell death of human SH-SY5Y cells
  83. Peroxisome proliferator‐activated receptor gamma coactivator‐1 alpha (PGC‐1α) upregulated E‐cadherin expression in HepG2 cells
  84. Tandem duplication/triplication correlated with poly-cytosine stretch variation in human mitochondrial DNA D-loop region
  85. Mitochondria Are an Essential Mediator of Nitric Oxide/Cyclic Guanosine 3′,5′-Monophosphate Blocking of Glucose Depletion–Induced Cytotoxicity in Human HepG2 Cells
  86. Open Reading Frame 8a of the Human Severe Acute Respiratory Syndrome Coronavirus Not Only Promotes Viral Replication but Also Induces Apoptosis
  87. Enhanced oxidative stress and aberrant mitochondrial biogenesis in human neuroblastoma SH-SY5Y cells during methamphetamine induced apoptosis
  88. Heteroplasmic mutation of mitochondrial DNA D-loop and 4977-bp deletion in human cancer cells during mitochondrial DNA depletion
  89. Anticancer effects of low-dose 10-hydroxycamptothecin in human colon cancer
  90. Aberrant methylation of EDNRB and p16 genes in hepatocellular carcinoma (HCC) in Taiwan
  91. Increases of Mitochondrial Mass and Mitochondrial Genome in Association with Enhanced Oxidative Stress in Human Cells Harboring 4,977 BP-Deleted Mitochondrial DNA
  92. Mitochondrial DNA mutations and mitochondrial DNA depletion in breast cancer
  93. Accumulation of mitochondrial DNA with 4977-bp deletion in knee cartilage – an association with idiopathic osteoarthritis
  94. Mitochondrial DNA mutations and mitochondrial DNA depletion in gastric cancer
  95. Mitochondrial Genome Instability and mtDNA Depletion in Human Cancers
  96. Mitochondrial biogenesis and mitochondrial DNA maintenance of mammalian cells under oxidative stress
  97. Polymorphisms of estrogen-metabolizing genes and risk of hepatocellular carcinoma in Taiwan females
  98. Alteration of the copy number and deletion of mitochondrial DNA in human hepatocellular carcinoma
  99. Somatic mutations in the D-loop and decrease in the copy number of mitochondrial DNA in human hepatocellular carcinoma
  100. Increased expression of manganese-superoxide dismutase in fibroblasts of patients with CPEO syndrome
  101. Mitochondrial DNA mutations and oxidative stress in mitochondrial diseases
  102. Oxidative Stress, Mitochondrial DNA Mutation, and Impairment of Antioxidant Enzymes in Aging
  103. Increase in mitochondrial mass in human fibroblasts under oxidative stress and during replicative cell senescence
  104. Wernicke’s Encephalopathy in a Patient with Multiple Symmetrical Lipomatosis and the A8344G Mutation of Mitochondrial DNA
  105. Enhanced oxidative damage in human cells harboring A3243G mutation of mitochondrial DNA: implication of oxidative stress in the pathogenesis of mitochondrial diabetes
  106. Coenzyme Q10 treatment in Leber's hereditary optic neuropathy
  107. Accumulation of mitochondrial DNA deletions in human oral tissues — effects of betel quid chewing and oral cancer
  108. Involvement of nervous system in maternally inherited diabetes and deafness (MIDD) with the A3243G mutation of mitochondrial DNA
  109. Clinical phenotype and the G11778A mutation of mitochondrial DNA in patients with Leber’s hereditary optic neuropathy in Taiwan
  110. Increase of mitochondria and mitochondrial DNA in response to oxidative stress in human cells
  111. Increase of mitochondria and mitochondrial DNA in response to oxidative stress in human cells
  112. Mitochondrial role in life and death of the cell
  113. Mitochondrial Role in Life and Death of the Cell
  114. Oxidative stress is insignificant in N1S1-transplanted hepatoma despite markedly declined activities of the antioxidant enzymes.
  115. Exclusive Homoplasmic 11778 Mutation in Mitochondrial DNA of Chinese Patients With Leber's Hereditary Optic Neuropathy
  116. Concurrent Increase of Oxidative DNA Damage and Lipid Peroxidation Together with Mitochondrial DNA Mutation in Human Lung Tissues During Aging—Smoking Enhances Oxidative Stress on the Aged Tissues
  117. Oxidative damage elicited by imbalance of free radical scavenging enzymes is associated with large-scale mtDNA deletions in aging human skin
  118. Human lung accumulates mitochondrial DNA mutations in aging and in smokers.
  119. Oxidative Damage and Mutation to Mitochondrial DNA and Age-dependent Decline of Mitochondrial Respiratory Functiona
  120. Independent occurrence of somatic mutations in mitochondrial DNA of human skin from subjects of various ages
  121. Decreased cellular respiratory function and mitochondrial DNA mutations in the human heart associated with ageing and disease
  122. Role of mitochondria in human aging
  123. Simultaneous Increase of Mitochondrial DNA Deletions and Lipid Peroxidation in Human Aging
  124. Tandem Duplications and Large-Scale Deletions of Mitochondrial DNA Are Early Molecular Events of Human Aging Process
  125. Compensatory elevation of complex II activity in Leber's hereditary optic neuropathy.
  126. Photoageing-associated mitochondrial DNA length mutations in human skin
  127. MELAS syndrome associated with diabetes mellitus and hyperthyroidism: a case report from Taiwan
  128. Ageing-associated tandem duplications in the D-loop of mitochondrial DNA of human muscle
  129. Human Skin Mitochondrial DNA Deletions Associated with Light Exposure
  130. A specific 4977-bp deletion of mitochondrial DNA in human ageing skin
  131. MELAS syndrome with mitochondrial tRNA(Leu(UUR)) gene mutation in a Chinese family.
  132. Differential accumulations of 4,977 bp deletion in mitochondrial DNA of various tissues in human ageing
  133. Age-dependent increase of mitochondrial DNA deletions together with lipid peroxides and superoxide dismutase in human liver mitochondria