All Stories

  1. Comparative primary paediatric nasal epithelial cell culture differentiation and RSV-induced cytopathogenesis following culture in two commercial media

    Article • PLoS ONE, March 2020, PLOS

    Prof. Ultan F Power, Professor Adnan Custovic

  2. Airway Surface Liquid Has Innate Antiviral Activity That Is Reduced in Cystic Fibrosis

    Article • American Journal of Respiratory Cell and Molecular Biology, January 2020, American Thoracic Society

    Prof. Ultan F Power, Steven Varga

  3. Airway Epithelial Derived Cytokines and Chemokines and Their Role in the Immune Response to Respiratory Syncytial Virus Infection

    Article • Pathogens, July 2019, MDPI AG

    Prof. Ultan F Power

  4. The viral protein corona directs viral pathogenesis and amyloid aggregation

    Article • Nature Communications, May 2019, Springer Science + Business Media

    Prof. Ultan F Power

  5. Characterisation of morphological differences in well-differentiated nasal epithelial cell cultures from preterm and term infants at birth and one-year

    Article • PLoS ONE, December 2018, PLOS

    Michael Shields, Prof. Ultan F Power

  6. Causes of variability in latent phenotypes of childhood wheeze

    Article • Journal of Allergy and Clinical Immunology, December 2018, Elsevier

    Prof. John W Holloway, Prof. Ultan F Power, Professor Adnan Custovic

  7. The Role of Toll-like receptor 4 in respiratory syncytial virus replication, interferon lambda 1 induction, and chemokine responses

    Article • August 2018, Cold Spring Harbor Laboratory Press

    Prof. Ultan F Power

  8. Phylogenetic analysis of porcine reproductive and respiratory syndrome virus isolates from Northern Ireland

    Article • Archives of Virology, May 2018, Springer Science + Business Media

    Prof. Ultan F Power

  9. Pulmonary epithelial barrier and immunological functions at birth and in early life - key determinants of the development of asthma?  A description of the protocol for the Breathing Together study

    Article • Wellcome Open Research, May 2018, Faculty of 1000, Ltd.

    Michael Shields, Prof. Ultan F Power, Professor Adnan Custovic

  10. The Viral Protein Corona Directs Viral Pathogenesis and Amyloid Aggregation

    Article • January 2018, Cold Spring Harbor Laboratory Press

    Prof. Ultan F Power

  11. Pro-inflammatory mediator responses from neonatal airway epithelial cells and early childhood wheeze

    Article • Pediatric Pulmonology, November 2017, Wiley

    Prof. Ultan F Power

  12. Revisiting the RSV G protein as a target for drugs and vaccines.

    Article • Journal of Virology, November 2017, ASM Journals

    Prof. Ultan F Power, Professor Ralph A Tripp

  13. New insights into the control of interferon responses following Sendai virus infection

    Article • Scientific Reports, November 2017, Nature

    Prof. Ultan F Power

  14. Broad-Spectrum Inhibition of Respiratory Virus Infection by MicroRNA Mimics Targeting p38 MAPK Signaling

    Article • Molecular Therapy — Nucleic Acids, June 2017, Elsevier

    Prof. Ultan F Power

  15. Antibody-Induced Internalization of the Human Respiratory Syncytial Virus Fusion Protein

    Article • Journal of Virology, May 2017, ASM Journals

    Prof. Ultan F Power

  16. Respiratory virus infection up-regulates TRPV1, TRPA1 and ASICS3 receptors on airway cells

    Article • PLoS ONE, February 2017, PLOS

    Prof. Ultan F Power

  17. EGFR Interacts with the Fusion Protein of Respiratory Syncytial Virus Strain 2-20 and Mediates Infection and Mucin Expression

    Article • PLoS Pathogens, May 2016, PLOS

    Prof. Ultan F Power

  18. In Vitro Modeling of RSV Infection and Cytopathogenesis in Well-Differentiated Human Primary Airway Epithelial Cells (WD-PAECs)

    Article • January 2016, Springer Science + Business Media

    Prof. Ultan F Power

  19. Generation and Characterization of ALX-0171, a Potent Novel Therapeutic Nanobody for the Treatment of Respiratory Syncytial Virus Infection

    Article • Antimicrobial Agents and Chemotherapy, October 2015, ASM Journals

    Prof. Ultan F Power, Dr Laurent Detalle

  20. Respiratory syncytial virus and type III interferon responses

    Article • Journal of Virology, September 2015, ASM Journals

    Prof. Ultan F Power

  21. Primary airway epithelial cell culture and asthma in children-lessons learnt and yet to come

    Article • Pediatric Pulmonology, July 2015, Wiley

    Prof. Ultan F Power

  22. Respiratory syncytial virus, an ongoing medical dilemma: an expert commentary on respiratory syncytial virus prophylactic and therapeutic pharmaceuticals currently in clinical trials

    Article • Influenza and Other Respiratory Viruses, June 2015, Wiley

    Prof. Ultan F Power

  23. Dissolving Microneedle Delivery of Nanoparticle-Encapsulated Antigen Elicits Efficient Cross-Priming and Th1 Immune Responses by Murine Langerhans Cells

    Article • Journal of Investigative Dermatology, February 2015, Elsevier

    Professor Ryan F Donnelly, Prof. Ultan F Power

  24. Erratum: A 3-D well-differentiated model of pediatric bronchial epithelium demonstrates-unstimulated morphological differences between asthmatic and nonasthmatic cells

    Article • Pediatric Research, October 2014, Springer Science + Business Media

    Prof. Ultan F Power

  25. Epidermal Growth Factor Receptor (EGFR) Mediates Cell Fusion and Infectivity Of Respiratory Syncytial Virus (RSV)

    Article • Journal of Allergy and Clinical Immunology, February 2014, Elsevier

    Prof. Ultan F Power

  26. Relative Respiratory Syncytial Virus Cytopathogenesis in Upper and Lower Respiratory Tract Epithelium

    Article • American Review of Respiratory Disease, October 2013, American Thoracic Society

    Prof. Ultan F Power

  27. Affinity-Purified Respiratory Syncytial Virus Antibodies from Intravenous Immunoglobulin Exert Potent Antibody-Dependent Cellular Cytotoxicity

    Article • PLoS ONE, July 2013, PLOS

    Prof. Ultan F Power

  28. Respiratory syncytial virus interaction with human airway epithelium

    Article • Trends in Microbiology, May 2013, Elsevier

    Prof. Ultan F Power

  29. Skin Dendritic Cell Targeting via Microneedle Arrays Laden with Antigen-Encapsulated Poly-d,l-lactide-co-Glycolide Nanoparticles Induces Efficient Antitumor and Antiviral Immune Responses

    Article • ACS Nano, February 2013, American Chemical Society (ACS)

    Professor Ryan F Donnelly, Prof. Ultan F Power

  30. The Respiratory Syncytial Virus G Protein Conserved Domain Induces a Persistent and Protective Antibody Response in Rodents

    Article • PLoS ONE, March 2012, PLOS

    Prof. Ultan F Power

  31. In vitro modeling of respiratory syncytial virus infection of pediatric bronchial epithelium, the primary target of infection in vivo

    Article • Proceedings of the National Academy of Sciences, March 2012, Proceedings of the National Academy of Sciences

    Prof. Ultan F Power

  32. Cellular and Molecular Characteristics of RSV-Induced Disease in Humans

    Article • November 2011, IntechOpen

    Prof. Ultan F Power

  33. Differential cytopathogenesis of respiratory syncytial virus prototypic and clinical isolates in primary pediatric bronchial epithelial cells

    Article • Virology Journal, January 2011, Springer Science + Business Media

    Prof. Ultan F Power

  34. Cytopathogenesis of Sendai Virus in Well-Differentiated Primary Pediatric Bronchial Epithelial Cells

    Article • Journal of Virology, September 2010, ASM Journals

    Prof. Ultan F Power

  35. Report of the 2nd “French Clinical Vaccinology Meeting Jean-Gerard Guillet”: Immunization and respiratory diseases

    Article • Vaccine, September 2010, Elsevier

    Prof. Ultan F Power

  36. A 3-D Well-Differentiated Model of Pediatric Bronchial Epithelium Demonstrates Unstimulated Morphological Differences Between Asthmatic and Nonasthmatic Cells

    Article • Pediatric Research, January 2010, Nature

    Prof. Ultan F Power

  37. De novo generation of a non-segmented negative strand RNA virus with a bicistronic gene

    Article • Virus Research, March 2009, Elsevier

    Prof. Ultan F Power

  38. Respiratory syncytial virus (RSV) vaccines—Two steps back for one leap forward

    Article • Journal of Clinical Virology, January 2008, Elsevier

    Prof. Ultan F Power

  39. Neonatal human autologous dendritic cells pulsed with recombinant protein antigen prime the generation of non-polarized CD4 T-cell effectors

    Article • International Immunology, May 2007, Oxford University Press (OUP)

    Prof. Ultan F Power

  40. Respiratory Syncytial Virus NS1 Protein Degrades STAT2 by Using the Elongin-Cullin E3 Ligase

    Article • Journal of Virology, January 2007, ASM Journals

    Prof. Ultan F Power, Dr Nigel J Stevenson

  41. Evaluation of a novel Vi conjugate vaccine in a murine model of salmonellosis

    Article • Vaccine, May 2006, Elsevier

    Prof. Ultan F Power

  42. Protective Levels of Polysaccharide-Specific Maternal Antibodies May Enhance the Immune Response Elicited by Pneumococcal Conjugates in Neonatal and Infant Mice

    Article • Infection and Immunity, February 2005, ASM Journals

    Prof. Ultan F Power

  43. Evaluation of BBG2Na in infant macaques: specific immune responses after vaccination and RSV challenge

    Article • Vaccine, February 2004, Elsevier

    Prof. Ultan F Power

  44. Immunization of Female Mice with Glycoconjugates Protects Their Offspring against Encapsulated Bacteria

    Article • Infection and Immunity, January 2004, ASM Journals

    Prof. Ultan F Power

  45. The immunogenicity, protective efficacy and safety of BBG2Na, a subunit respiratory syncytial virus (RSV) vaccine candidate, against RSV-B

    Article • Vaccine, December 2003, Elsevier

    Prof. Ultan F Power

  46. Enhanced pulmonary immunopathology following neonatal priming with formalin-inactivated respiratory syncytial virus but not with the BBG2NA vaccine candidate

    Article • Vaccine, June 2003, Elsevier

    Prof. Ultan F Power

  47. Structure-antigenicity relationship studies of the central conserved region of human respiratory syncytial virus protein G

    Article • Journal of Peptide Research, November 2002, Wiley

    Prof. Ultan F Power

  48. Differential Histopathology and Chemokine Gene Expression in Lung Tissues following Respiratory Syncytial Virus (RSV) Challenge of Formalin-Inactivated RSV- or BBG2Na-Immunized Mice

    Article • Journal of Virology, December 2001, ASM Journals

    Prof. Ultan F Power

  49. Safety and Immunogenicity of a Novel Recombinant Subunit Respiratory Syncytial Virus Vaccine (BBG2Na) in Healthy Young Adults

    Article • The Journal of Infectious Diseases, December 2001, Oxford University Press (OUP)

    Prof. Ultan F Power

  50. Mammalian cell production of a respiratory syncytial virus (RSV) candidate vaccine recovered using a product-specific affinity column

    Article • Biotechnology and Applied Biochemistry, August 2001, Wiley

    Prof. Ultan F Power

  51. A novel bipolar mode of attachment to aluminium-containing adjuvants by BBG2Na, a recombinant subunit hRSV vaccine

    Article • Vaccine, July 2001, Elsevier

    Prof. Ultan F Power

  52. Identification and characterisation of multiple linear B cell protectopes in the respiratory syncytial virus G protein

    Article • Vaccine, March 2001, Elsevier

    Prof. Ultan F Power

  53. Protection against respiratory syncytial virus (RSV) elicited in mice by plasmid DNA immunisation encoding a secreted RSV G protein-derived antigen

    Article • FEMS Immunology & Medical Microbiology, December 2000, Oxford University Press (OUP)

    Prof. Ultan F Power

  54. Protection against respiratory syncytial virus (RSV) elicited in mice by plasmid DNA immunisation encoding a secreted RSV G protein-derived antigen

    Article • FEMS Immunology & Medical Microbiology, December 2000, Wiley

    Prof. Ultan F Power

  55. Influence of administration dose and route on the immunogenicity and protective efficacy of BBG2Na, a recombinant respiratory syncytial virus subunit vaccine candidate

    Article • Vaccine, June 2000, Elsevier

    Prof. Ultan F Power

  56. CD4+ T-Cell-Mediated Antiviral Protection of the Upper Respiratory Tract in BALB/c Mice following Parenteral Immunization with a Recombinant Respiratory Syncytial Virus G Protein Fragment

    Article • Journal of Virology, April 2000, ASM Journals

    Prof. Ultan F Power

  57. Protective Efficacy against Respiratory Syncytial Virus following Murine Neonatal Immunization with BBG2Na Vaccine: Influence of Adjuvants and Maternal Antibodies

    Article • The Journal of Infectious Diseases, June 1999, Oxford University Press (OUP)

    Prof. Ultan F Power

  58. Absence of Lung Immunopathology Following Respiratory Syncytial Virus (RSV) Challenge in Mice Immunized with a Recombinant RSV G Protein Fragment

    Article • Virology, May 1999, Elsevier

    Prof. Ultan F Power

  59. An in vitro selected binding protein (affibody) shows conformation-dependent recognition of the respiratory syncytial virus (RSV) G protein

    Article • Immunotechnology, March 1999, Elsevier

    Prof. Ultan F Power

  60. Protective Immunity against Respiratory Syncytial Virus in Early Life after Murine Maternal or Neonatal Vaccination with the Recombinant G Fusion Protein BBG2Na

    Article • The Journal of Infectious Diseases, October 1997, Oxford University Press (OUP)

    Prof. Ultan F Power

  61. Challenge of BALB/c Mice with Respiratory Syncytial Virus Does Not Enhance the Th2 Pathway Induced after Immunization with a Recombinant G Fusion Protein, BBG2NA, in Aluminum Hydroxide

    Article • The Journal of Infectious Diseases, September 1997, Oxford University Press (OUP)

    Prof. Ultan F Power

  62. Induction of Protective Immunity in Rodents by Vaccination with a Prokaryotically Expressed Recombinant Fusion Protein Containing a Respiratory Syncytial Virus G Protein Fragment

    Article • Virology, April 1997, Elsevier

    Prof. Ultan F Power

  63. Hydrophobicity Engineering to Increase Solubility and Stability of a Recombinant Protein from Respiratory Syncytial Virus

    Article • European Journal of Biochemistry, May 1995, Wiley

    Prof. Ultan F Power

  64. Hydrophobicity Engineering to Increase Solubility and Stability of a Recombinant Protein from Respiratory Syncytial Virus

    Article • FEBS Journal, May 1995, Wiley

    Prof. Ultan F Power

  65. Selective interference with P protein binding to paramyxovirus nucleocapsids

    Article • Virus Research, June 1994, Elsevier

    Prof. Ultan F Power

  66. Viral Cross-Reactivity and Antigenic Determinants Recognized by Human Parainfluenza Virus Type 1-Specific Cytotoxic T-Cells

    Article • Virology, March 1994, Elsevier

    Prof. Ultan F Power

  67. Sequence characterization and expression of the matrix protein gene of human parainfluenza virus type 1

    Article • Virology, December 1992, Elsevier

    Prof. Ultan F Power

  68. The P genes of human parainfluenza virus type 1 clinical isolates are polycistronic and microheterogenous

    Article • Virology, July 1992, Elsevier

    Prof. Ultan F Power