All Stories

  1. COVID-19 and tuberculosis: the double whammy of respiratory pathogens
  2. The PGRS Domain of Mycobacterium tuberculosis PE_PGRS Protein Rv0297 Is Involved in Endoplasmic Reticulum Stress-Mediated Apoptosis through Toll-Like Receptor 4
  3. Contrasting Function of Structured N-Terminal and Unstructured C-Terminal Segments of Mycobacterium tuberculosis PPE37 Protein
  4. Mycobacterium tuberculosis Co-operonic PE32/PPE65 Proteins Alter Host Immune Responses by Hampering Th1 Response
  5. Mycobacterium tuberculosis Peptidyl-Prolyl Isomerases Also Exhibit Chaperone like Activity In-Vitro and In-Vivo
  6. Interaction of Mycobacterium tuberculosis Virulence Factor RipA with Chaperone MoxR1 Is Required for Transport through the TAT Secretion System
  7. Analyses of methyltransferases across the pathogenicity spectrum of different mycobacterial species point to an extremophile connection
  8. Orchestration of membrane receptor signaling by membrane lipids
  9. 10.1016/j.tube.2014.12.007
  10. Reply to ‘“Mycobacterium indicus pranii” Is a Strain of Mycobacterium intracellulare’: “M. indicus pranii” Is a Distinct Strain, Not Derived from M. intracellulare, and Is an Organism at an Evolutionary Transition Point between a Fast Grower and Slow G...
  11. Whole genome sequencing: A new paradigm in the surveillance and control of human tuberculosis
  12. Proteomics of multidrug resistant Mycobacterium tuberculosis clinical isolates: A peep show on mechanism of drug resistance & perhaps more
  13. Erratum for Rahman et al., Comparative Analyses of Nonpathogenic, Opportunistic, and Totally Pathogenic Mycobacteria Reveal Genomic and Biochemical Variabilities and Highlight the Survival Attributes of Mycobacterium tuberculosis
  14. Comparative genomic analysis of Helicobacter pylori from Malaysia identifies three distinct lineages suggestive of differential evolution
  15. Comparative Analyses of Nonpathogenic, Opportunistic, and Totally Pathogenic Mycobacteria Reveal Genomic and Biochemical Variabilities and Highlight the Survival Attributes of Mycobacterium tuberculosis
  16. Mycobacterium avium subsp. paratuberculosis is not discerned in diabetes mellitus patients in Hyderabad, India
  17. Gene cooption in Mycobacteria and search for virulence attributes: Comparative proteomic analyses of Mycobacterium tuberculosis, Mycobacterium indicus pranii and other mycobacteria
  18. Genomic Fluidity of the Human Gastric Pathogen Helicobacter pylori
  19. In silico characterization of a putative ORF-MAP1138c of Mycobacterium avium subspecies paratuberculosis(MAP) with its implications in virulence
  20. A novel immunomodulatory function of PHLPP1: inhibition of iNOS via attenuation of STAT1 ser727 phosphorylation in mouse macrophages
  21. Optimism, Hope, and Happiness as correlates of Psychological Well-Being among Young Adult Assamese Males and Females.
  22. Mycobacterium tuberculosisPE25/PPE41 protein complex induces necrosis in macrophages: Role in virulence and disease reactivation?
  23. Dormancy Associated Translation Inhibitor (DATIN/Rv0079) of Mycobacterium tuberculosis interacts with TLR2 and induces proinflammatory cytokine expression
  24. Spodoptera frugiperdaFKBP-46 is a consensus p53 motif binding protein
  25. Emerging importance of holobionts in evolution and in probiotics
  26. Massive gene acquisitions in Mycobacterium indicus pranii provide a perspective on mycobacterial evolution
  27. Mycobacterium tuberculosis DosR Regulon Gene Rv0079 Encodes a Putative, ‘Dormancy Associated Translation Inhibitor (DATIN)’
  28. Comparative genomic and proteomic analyses of PE/PPE multigene family of Mycobacterium tuberculosis H37Rv and H37Ra reveal novel and interesting differences with implications in virulence
  29. Climate change and infectious diseases – Impact of global warming and climate change on infectious diseases: Myth or reality?
  30. The PE/PPE multigene family codes for virulence factors and is a possible source of mycobacterial antigenic variation: Perhaps more?
  31. Modern and Ancestral Genotypes of Mycobacterium tuberculosis from Andhra Pradesh, India
  32. Baculovirus p35 gene is oppositely regulated by P53 and AP-1 like factors in Spodoptera frugiperda
  33. The translation initiation factor, PeIF5B, from Pisum sativum displays chaperone activity
  34. Molecular epidemiology of tuberculosis in India: Moving forward with a systems biology approach
  35. Synergy between the N-terminal and C-terminal domains of Mycobacterium tuberculosis HupB is essential for high-affinity binding, DNA supercoiling and inhibition of RecA-promoted strand exchange
  36. Concurrent Proinflammatory and Apoptotic Activity of a Helicobacter pylori Protein (HP986) Points to Its Role in Chronic Persistence
  37. Iron acquisition, assimilation and regulation in mycobacteria
  38. Treatment end point determinants for pulmonary tuberculosis: Human resistin as a surrogate biomarker
  39. Translating Advances in Genomic Research into Clinical Practice: The Challenges Ahead
  40. A Link between Mitochondrial DNA Haplogroup and Ischemia
  41. Transcriptional Regulation of Mycobacterium tuberculosis PE/PPE Genes: A Molecular Switch to Virulence
  42. Enhanced T cell responsiveness to Mycobacterium bovis BCG r32-kDa Ag correlates with successful anti-tuberculosis treatment in humans
  43. Expression, purification and ligand binding properties of the recombinant translation initiation factor (PeIF5B) from Pisum sativum
  44. DNA Clasping by Mycobacterial HU: The C-Terminal Region of HupB Mediates Increased Specificity of DNA Binding
  45. Mycobacterium tuberculosisconserved hypothetical protein rRv2626c modulates macrophage effector functions
  46. Transcription of Human Resistin Gene Involves an Interaction of Sp1 with Peroxisome Proliferator-Activating Receptor Gamma (PPARγ)
  47. Mapping Conformational Transitions in Cyclic AMP Receptor Protein: Crystal Structure and Normal-Mode Analysis of Mycobacterium tuberculosis apo-cAMP Receptor Protein
  48. The PPE18 of Mycobacterium tuberculosis Interacts with TLR2 and Activates IL-10 Induction in Macrophage
  49. Characterization of LEF4 ligand binding property and its role as part of baculoviral transcription machinery
  50. Polyphasic Taxonomic Analysis Establishes Mycobacterium indicus pranii as a Distinct Species
  51. Biophysical characterization and unfolding of LEF4 factor of RNA polymerase fromAcNPV
  52. Octamer and heat shock elements regulate transcription from the AcMNPV polyhedrin gene promoter
  53. Specific Immunoassays Confirm Association of Mycobacterium avium Subsp. paratuberculosis with Type-1 but Not Type-2 Diabetes Mellitus
  54. In-Vitro Helix Opening of M. tuberculosis oriC by DnaA Occurs at Precise Location and Is Inhibited by IciA Like Protein
  55. Ancestral Mycobacterium tuberculosis genotypes in India: Implications for TB control programmes
  56. Baculovirus P35 protein: An overview of its applications across multiple therapeutic and biotechnological arenas
  57. Gut Pathogens: enteric health at the interface of changing microbiology
  58. In Vitro Levels of Interleukin 10 (IL-10) and IL-12 in Response to a Recombinant 32-Kilodalton Antigen of Mycobacterium bovis BCG after Treatment for Tuberculosis
  59. The Co-Operonic PE25/PPE41 Protein Complex of Mycobacterium tuberculosis Elicits Increased Humoral and Cell Mediated Immune Response
  60. Mycobacterium tuberculosisheat shock protein 60 modulates immune response to PPD by manipulating the surface expression of TLR2 on macrophages
  61. Mechanistic Insights into a Novel Exporter-Importer System of Mycobacterium tuberculosis Unravel Its Role in Trafficking of Iron
  62. Pathogenomics: An updated European Research Agenda
  63. Genomic fluidity and pathogenic bacteria: applications in diagnostics, epidemiology and intervention
  64. Genome scale portrait of cAMP-receptor protein (CRP) regulons in mycobacteria points to their role in pathogenesis
  65. Novel biochemical properties of a CRP/FNR family transcription factor from Mycobacterium tuberculosis
  66. Molecular Analysis of a Leprosy Immunotherapeutic Bacillus Provides Insights into Mycobacterium Evolution
  67. Pisum sativum contains a factor with strong homology to eIF5B
  68. Biochemical characterization of Sf9 Sp-family-like protein factors reveals interesting features
  69. High-Resolution Genome Profiling DifferentiatedStaphylococcus epidermidisIsolated from Patients with Ocular Infections and Normal Individuals
  70. Nitric Oxide: Friendly Rivalry in Tuberculosis
  71. Iron-Dependent RNA-Binding Activity of Mycobacterium tuberculosis Aconitase
  72. Nitric oxide inhibits interleukin-12 p40 through p38 MAPK-mediated regulation of calmodulin and c-rel
  73. Anti-B7-1/B7-2 antibody elicits innate-effector responses in macrophages through NF- B-dependent pathway
  74. Disease-Causing Mutations in Proteins: Structural Analysis of the CYP1b1 Mutations Causing Primary Congenital Glaucoma in Humans
  75. Predominance of Ancestral Lineages of Mycobacterium tuberculosis in India
  76. Crystallization and preliminary X-ray crystallographic studies ofMycobacterium tuberculosisCRP/FNR family transcription regulator
  77. The 2.15 Å Crystal Structure of Mycobacterium tuberculosis Chorismate Mutase Reveals an Unexpected Gene Duplication and Suggests a Role in Host−Pathogen Interactions †
  78. Hydrogen peroxide inhibits IL-12 p40 induction in macrophages by inhibiting c-rel translocation to the nucleus through activation of calmodulin protein
  79. Clusters of PE and PPE genes ofMycobacterium tuberculosisare organized in operons: Evidence that PE Rv2431c is co-transcribed with PPE Rv2430c and their gene products interact with each other
  80. Fluorescent amplified fragment length polymorphism (FAFLP) genotyping demonstrates the role of biofilm-producing methicillin-resistant periocular Staphylococcus epidermidis strains in postoperative endophthalmitis
  81. Rapid Identification of Mycobacterium tuberculosis Beijing Genotypes on the Basis of the Mycobacterial Interspersed Repetitive Unit Locus 26 Signature
  82. Characterization of Naturally Occurring and Lamivudine-Induced Surface Gene Mutants of Hepatitis B Virus in Patients with Chronic Hepatitis B in India
  83. Analysis of Genomic Downsizing on the Basis of Region-of-Difference Polymorphism Profiling of Mycobacterium tuberculosis Patient Isolates Reveals Geographic Partitioning
  84. Indian herb ‘Sanjeevani’ (Selaginella bryopteris) can promote growth and protect against heat shock and apoptotic activities of ultra violet and oxidative stress
  85. Crystallization and preliminary X-ray crystallographic studies ofMycobacterium tuberculosischorismate mutase
  86. Purified Recombinant Hypothetical Protein Coded by Open Reading Frame Rv1885c of Mycobacterium tuberculosis Exhibits a Monofunctional AroQ Class of Periplasmic Chorismate Mutase Activity
  87. pheA (Rv3838c) of Mycobacterium tuberculosis Encodes an Allosterically Regulated Monofunctional Prephenate Dehydratase That Requires Both Catalytic and Regulatory Domains for Optimum Activity
  88. Computational prediction and experimental verification of novel IdeR binding sites in the upstream sequences of Mycobacterium tuberculosis open reading frames
  89. Interleukin-10 (IL-10) mediated suppression of IL-12 production in RAW 264.7 cells also involves c-rel transcription factor
  90. Myocilin gene implicated in primary congenital glaucoma
  91. Transmission of G145R mutant of HBV to an unrelated contact
  92. High resolution genotyping of P aerugonisa
  93. Comparison of Mtb isocitrate dehydrogenase
  94. The extracytoplasmic function sigma factors: role in bacterial pathogenesis
  95. Regions of High Antigenicity within the Hypothetical PPE Major Polymorphic Tandem Repeat Open‐Reading Frame, Rv2608, Show a Differential Humoral Response and a Low T Cell Response in Various Categories of Patients with Tuberculosis
  96. Leptospirosis
  97. Mycobacterium tuberculosis ( Mtb ) isocitrate dehydrogenases show strong B cell response and distinguish vaccinated controls from TB patients
  98. Use of Fluorescent Amplified Fragment Length Polymorphism for Molecular Epidemiology of Leptospirosis in India
  99. Expression and characterization of Rv2430c, a novel immunodominant antigen of Mycobacterium tuberculosis
  100. Molecular Genotyping of a Large, Multicentric Collection of Tubercle Bacilli Indicates Geographical Partitioning of Strain Variation and Has Implications for Global Epidemiology of Mycobacterium tuberculosis
  101. An Additional Copy of the Homologous Region (hr1) Sequence in the Autographa californica Multinucleocapsid Polyhedrosis Virus Genome Promotes Hyperexpression of Foreign Genes †
  102. Poorer NF-κB signaling by microfilariae in macrophages from BALB/c mice affects their ability to produce cytotoxic levels of nitric oxide to kill microfilariae
  103. Mycobacterium tuberculosis Isolate with a Distinct Genomic Identity Overexpresses a Tap-Like Efflux Pump
  104. Fibroin Silk Proteins from the Nonmulberry Silkworm Philosamia ricini Are Biochemically and Immunochemically Distinct from Those of the Mulberry Silkworm Bombyx mori
  105. AmpliBASE MTTM: a Mycobacterium tuberculosis diversity knowledgebase
  106. Defining the Mandate of Tuberculosis Research in a Postgenomic Era
  107. Genomics of the human Y-chromosome
  108. Stress-Induced Apoptosis in Spodoptera frugiperda ( Sf 9) Cells:  Baculovirus p35 Mitigates eIF2α Phosphorylation †
  109. PPE Antigen Rv2430c of Mycobacterium tuberculosis Induces a Strong B-Cell Response
  110. The Homologous Region Sequence (hr1) of Autographa californica Multinucleocapsid Polyhedrosis Virus Can Enhance Transcription from Non-baculoviral Promoters in Mammalian Cells
  111. Identification of R368H as a Predominant CYP1B1 Allele Causing Primary Congenital Glaucoma in Indian Patients
  112. Baculoviral p35 inhibits oxidant-induced activation of mitochondrial apoptotic pathway
  113. Antioxidants prevent UV-induced apoptosis by inhibiting mitochondrial cytochrome c release and caspase activation in Spodoptera frugiperda (Sf9) cells
  114. Distinctiveness of Mycobacterium tuberculosis Genotypes from Human Immunodeficiency Virus Type 1-Seropositive and -Seronegative Patients in Lima, Peru
  115. Host-pathogen interactions during apoptosis
  116. Genome sequence based, comparative analysis of the fluorescent amplified fragment length polymorphisms (FAFLP) of tubercle bacilli from seals provides molecular evidence for a new species within the Mycobacterium tuberculosis complex
  117. Prevalence and profile of mutations associated with lamivudine therapy in Indian patients with chronic hepatitis B in the surface and polymerase genes of hepatitis B virus
  118. Baculovirus as Mammalian Cell Expression Vector for Gene Therapy: An Emerging Strategy
  119. Genetic analysis of traditional and evolved Basmati and non-Basmati rice varieties by using fluorescence-based ISSR-PCR and SSR markers
  120. Vertical transmission of hepatitis B virus despite maternal lamivudine therapy
  121. TA-insertion mutation in bilirubin-UDP glucuronosyltransferase gene (UGT1A1) promoter in Indian patients with Gilbert's syndrome
  122. Molecular Characterization of Multidrug-Resistant Isolates of Mycobacterium tuberculosis from Patients in North India
  123. Molecular dissection of the human Y-chromosome
  124. Mutational analysis of the RB1 gene in Indian patients with retinoblastoma
  125. MEEGID-V: Fifth international meeting on molecular epidemiology and evolutionary genetics in infectious diseases
  126. Typing of drug resistant isolates of Mycobacterium tuberculosis from India using the IS6110 element reveals substantive polymorphism
  127. Specificity of drug transport mediated byCaMDR1: A major facilitator ofCandida albicans
  128. Novel Sp Family-like Transcription Factors Are Present in Adult Insect Cells and Are Involved in Transcription from the Polyhedrin Gene Initiator Promoter
  129. Phosphorylation of Serine 51 in Initiation Factor 2α (eIF2α) Promotes Complex Formation between eIF2α(P) and eIF2B and Causes Inhibition in the Guanine Nucleotide Exchange Activity of eIF2B †
  130. Molecular Characterization of Mycobacterium Abscessus Strains Isolated from a Hospital Outbreak
  131. Beneficial effects of lamivudine in hepatitis B virus-related decompensated cirrhosis
  132. Development, expression, and murine testing of a multistage Plasmodium falciparum malaria vaccine candidate
  133. Differential Activity of Two Non-hrOrigins during Replication of the Baculovirus Autographa californica Nuclear Polyhedrosis Virus Genome
  134. Mitochondria can power cells to life and death
  135. CDR1 , a multidrug resistance gene from Candida albicans , contains multiple regulatory domains in its promoter and the distal AP-1 element mediates its induction by miconazole
  136. Serine 48 in Initiation Factor 2α (eIF2α) Is Required for High-Affinity Interaction between eIF2α(P) and eIF2B †
  137. The baculovirus antiapoptotic p35 gene also functions via an oxidant-dependent pathway
  138. Invitro culturedSpodoptera frugiperda insect cells: Model for oxidative stress-induced apoptosis
  139. Immunogenicity and in vitro protective efficacy of a recombinant multistage Plasmodium falciparum candidate vaccine
  140. Analysis of the evolutionarily conserved repeat motifs in the genome of the highly endangered central Indian swamp deer Cervus duvauceli branderi1Published in conjunction with A Wisconsin Gathering Honoring Waclaw Szybalski on the occasion of his 75th ...
  141. Site-specific gene delivery in vivo through engineered Sendai viral envelopes
  142. Molecular Genetic Analysis of Multi-drug Resistance in Indian Isolates of Mycobacterium tuberculosis
  143. Development, characterization, and in vitro protective effects of a multi-stage P. falciparum candidate vaccine.
  144. Deletion of transmembrane domain 12 ofCDR1, a multidrug transporter fromCandida albicans, leads to altered drug specificity: Expression of a yeast multidrug transporter in baculovirus expression system
  145. Genetic alterations in brain tumors identified by RAPD analysis
  146. The HSD-hCG Vaccine Prevents Pregnancy in Women: Feasibility Study of a Reversible Safe Contraceptive Vaccine
  147. Involvement of host factors in transcription from baculovirus very late promoters - a review
  148. Development of a functional assay for Ca2+ release activity of IP3R and expression of an IP3R gene fragment in the baculovirus-insect cell system
  149. A 38-kDa Host Factor Interacts with Functionally Important Motifs within the Autographa californica Multinucleocapsid Nuclear Polyhedrosis Virus Homologous Region (hr1) DNA Sequence
  150. A One-Step Lysis Procedure for 18S Ribosomal RNA-Based Diagnosis of Infection byPlasmodiumSpecies
  151. Characterization of a human alphoid satellite DNA sequence: Potential use in assessing genetic diversity in Indian populations
  152. Bifunctionality of the AcMNPV Homologous Region Sequence (hr1): Enhancer andoriFunctions Have Different Sequence Requirements
  153. A 30-kDa Host Protein Binds to Two Very-Late Baculovirus Promoters
  154. Random amplified polymorphic DNA (RAPD) markers reveal genetic homogeneity in the endangered Himalayan species Meconopsis paniculata and M. simplicifolia
  155. A recombination-efficient baculovirus vector for simultaneous expression of multiple genes
  156. Expression and functional characterisation of the ClpC gene of Mycobacterium leprae: ClpC protein elicits human antibody response
  157. Host factor with single-stranded DNA-binding activity involved in transcription from baculovirus polyhedrin promoter
  158. Species-specific 18S rRNA gene amplification for the detection ofP. falciparumandP. vivaxmalaria parasites
  159. A multicopy DNA sequence from Meconopsis simplicifolia discriminates between the different species of this endangered Himalayan poppy
  160. The 30-kDa Protein Binding to the "Initiator" of the Baculovirus Polyhedrin Promoter Also Binds Specifically to the Coding Strand
  161. Transcriptional Regulation of Cell Line-Dependent, Baculovirus-Mediated Expression of Foreign Genes
  162. Influence of codon usage and translation initiation codon context in theAcNPV-based expression system: Computer analysis using homologous and heterologous genes
  163. DNA polymorphism analysis in five endangered species ofMeconopsis (Himalayan poppy) using multi-copy sequence-based probes
  164. β-Subunit of Human Chorionic Gonadotropin Hormone and Firefly Luciferase Simultaneously Synthesized in Insect Cells Using a Recombinant Baculovirus Are Differentially Expressed and Transported
  165. Differential secretion and glycosylation of recombinant human chorionic gonadotropin (ßhCG) synthesized using different promoters in the baculovirus expression vector system
  166. Temporal nature of the promoter and not relative strength determines the expression of an extensively processed protein in a baculovirus system
  167. Simultaneous synthesis of enzymatically active luciferase and biologically active β subunit of human chorionic gonadotropin in caterpillars infected with a recombinant baculovirus
  168. A novel probe for human DNA fingerprinting based on chi-like sequences
  169. A Multi-locus Probe for Human DNA Fingerprinting Based on chi-like Sequences
  170. The α subunit of human chorionic gonadotropin hormone synthesized in insect cells using a baculovirus vector is biologically active
  171. Nucleotide sequence of a human satellite DNA
  172. Firefly luciferase, synthesized to very high levels in caterpillars infected with a recombinant baculovirus, can also be used as an efficient reporter enzyme in vivo
  173. The mitochondrial apocytochrome b gene from Chlamydomonas reinhardtii
  174. Expression of the gene encoding firefly luciferase in insect cells using a baculovirus vector
  175. Nucleotide sequence of cloned nad4 (urf4) gene from Chlamydomonas reinhardtii mitochondrial DNA
  176. Characterization of the kafirin gene family from sorghum reveals extensive homology with zein from maize
  177. Nucleotide sequence of Chlamydomonas reinhardtii mitochondrial genes coding for tRNA Gla (UUG) and tRNA Met (CAU)
  178. Presence of DNA sequence homologous toRAS gene in the aquatic fungusAchlya ambisexualis: Possible role in sporangiogenesis
  179. Nucleotlde sequence of Chlamydomonas reinhardtii mitochondrial genes coding for subunit 6 of NADH dehydrogenase and tRNA Trp
  180. pXmnATG: an E.coli vector for expression of unfused proteins
  181. Expression of herpes simplex virus thymidine kinase gene in aquatic filamentous fungus achlya ambisexualis
  182. Array-Based Comparative Genomic Hybridization
  183. 8 Enigmatic Proteins from the Surface: the Erp, PE, and PPE Protein Families