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  1. Early-Life Skin Microbial Biomarkers for Eczema Phenotypes in Chinese Toddlers

    Article • Pathogens, May 2023, MDPI AG

    Professor Paul KS Chan

  2. Gut microbiome dysbiosis across early Parkinson’s disease, REM sleep behavior disorder and their first-degree relatives

    Article • Nature Communications, May 2023, Springer Science + Business Media

    Professor Paul KS Chan

  3. Interaction between Human Papillomavirus-Encoded E6 Protein and AurB Induces Cell Immortalization and Proliferation—A Potential Target of Intervention

    Article • Cancers, April 2023, MDPI AG

    Professor Paul KS Chan

  4. Public health impact of herpes zoster vaccination on older adults in Hong Kong

    Article • Human Vaccines & Immunotherapeutics, February 2023, Taylor & Francis

    Professor Martin CS Wong, Professor Paul KS Chan

  5. E6-Encoded by Cancer-Causing Human Papillomavirus Interacts with Aurora Kinase A To Promote HPV-Mediated Carcinogenesis

    Article • Journal of Virology, February 2023, ASM Journals

    Professor Paul KS Chan

  6. Preliminary Findings of the High Quantity of Microplastics in Faeces of Hong Kong Residents

    Article • Toxics, July 2022, MDPI AG

    Professor Paul KS Chan

  7. Major Adverse Cardiovascular Events and Mortality Prediction by Circulating GDF-15 in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis

    Article • Biomolecules, July 2022, MDPI AG

    Professor Paul KS Chan

  8. Review of the Standard and Advanced Screening, Staging Systems and Treatment Modalities for Cervical Cancer

    Article • Cancers, June 2022, MDPI AG

    Professor Paul KS Chan

  9. Oesophageal carcinoma: The prevalence of DNA tumour viruses and therapy

    Article • Tumour Virus Research, June 2022, Elsevier

    Professor Paul KS Chan

  10. Mucosal Antibody Response to SARS-CoV-2 in Paediatric and Adult Patients: A Longitudinal Study

    Article • Pathogens, March 2022, MDPI AG

    Professor Paul KS Chan

  11. Gut microbiota‐derived synbiotic formula (SIM01) as a novel adjuvant therapy for COVID‐19: An open‐label pilot study

    Article • Journal of Gastroenterology and Hepatology, March 2022, Wiley

    Professor Paul KS Chan

  12. Determinants and Interactions of Oral Bacterial and Fungal Microbiota in Healthy Chinese Adults

    Article • Microbiology Spectrum, February 2022, ASM Journals

    Professor Paul KS Chan

  13. Inhibition of Influenza Virus Replication by Oseltamivir Derivatives

    Article • Pathogens, February 2022, MDPI AG

    Professor Paul KS Chan

  14. Chimeric crRNA improves CRISPR–Cas12a specificity in the N501Y mutation detection of Alpha, Beta, Gamma, and Mu variants of SARS-CoV-2

    Article • PLoS ONE, December 2021, PLOS

    Professor Margaret Ip, Professor Paul KS Chan

  15. Host inflammatory response is the major marker of severe respiratory syncytial virus infection in older adults

    Article • Journal of Infection, December 2021, Elsevier

    Professor Paul KS Chan

  16. Characterization of key amino acid substitutions and dynamics of the influenza virus H3N2 hemagglutinin

    Article • Journal of Infection, December 2021, Elsevier

    Professor Paul KS Chan

  17. COVID-19 Vaccine Hesitancy in a City with Free Choice and Sufficient Doses

    Article • Vaccines, October 2021, MDPI AG

    Professor Martin CS Wong, Professor Paul KS Chan

  18. Temporal-Geographical Dispersion of SARS-CoV-2 Spike Glycoprotein Variant Lineages and Their Functional Prediction Using in Silico Approach

    Article • mBio, October 2021, ASM Journals

    Professor Paul KS Chan

  19. K-Mer Analyses Reveal Different Evolutionary Histories of Alpha, Beta, and Gamma Papillomaviruses

    Article • International Journal of Molecular Sciences, September 2021, MDPI AG

    Professor Paul KS Chan

  20. Suppression of influenza virus infection by rhinovirus interference at the population, individual and cellular levels

    Article • August 2021, Cold Spring Harbor Laboratory Press

    Professor Paul KS Chan, Professor Calvin S.H. Ng

  21. Current Updates on Cancer-Causing Types of Human Papillomaviruses (HPVs) in East, Southeast, and South Asia

    Article • Cancers, May 2021, MDPI AG

    Professor Paul KS Chan

  22. Inferring the Association between the Risk of COVID-19 Case Fatality and N501Y Substitution in SARS-CoV-2

    Article • Viruses, April 2021, MDPI AG

    Professor Paul KS Chan

  23. Integrated vaccination and physical distancing interventions to prevent future COVID-19 waves in Chinese cities

    Article • Nature Human Behaviour, February 2021, Springer Science + Business Media

    Professor Paul KS Chan

  24. Integrated vaccination and physical distancing interventions to prevent future COVID-19 waves

    Article • February 2021, Research Square

    Professor Paul KS Chan

  25. Interleukin-38 ameliorates poly(I:C) induced lung inflammation: therapeutic implications in respiratory viral infections

    Article • Cell Death and Disease, January 2021, Springer Science + Business Media

    Professor Paul KS Chan

  26. The Intersection between Oral Microbiota, Host Gene Methylation and Patient Outcomes in Head and Neck Squamous Cell Carcinoma

    Article • Cancers, November 2020, MDPI AG

    Professor Paul KS Chan

  27. Chemopreventive Role of Apigenin against the Synergistic Carcinogenesis of Human Papillomavirus and 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone

    Article • Biomedicines, November 2020, MDPI AG

    Professor Paul KS Chan

  28. SARS-CoV-2 detection by nasal strips: a superior tool for surveillance of pediatric populations

    Article • November 2020, Cold Spring Harbor Laboratory Press

    Professor Paul KS Chan

  29. Stringent containment measures without complete city lockdown to achieve low incidence and mortality across two waves of COVID-19 in Hong Kong

    Article • BMJ Global Health, October 2020, BMJ

    Professor Martin CS Wong, Professor Paul KS Chan

  30. Epidemiological characteristics of the first 100 cases of coronavirus disease 2019 (COVID-19) in Hong Kong Special Administrative Region, China, a city with a stringent containment policy

    Article • International Journal of Epidemiology, June 2020, Oxford University Press (OUP)

    Professor Paul KS Chan

  31. Persistence and clearance of oral human papillomavirus infections: a prospective population‐based cohort study

    Article • Journal of Medical Virology, June 2020, Wiley

    Professor Martin CS Wong, Professor Paul KS Chan

  32. Systematic review of human gut resistome studies revealed variable definitions and approaches

    Article • Gut Microbes, January 2020, Taylor & Francis

    Professor Paul KS Chan

  33. Human papillomavirus type 18 oncoproteins exert their oncogenicity in esophageal and tongue squamous cell carcinoma cell lines distinctly

    Article • December 2019, Research Square

    Professor Paul KS Chan

  34. Human papillomavirus type 18 oncoproteins exert their oncogenicity in esophageal and tongue squamous cell carcinoma cell lines distinctly

    Article • BMC Cancer, December 2019, Springer Science + Business Media

    Professor Paul KS Chan

  35. Human papillomavirus type 18 oncoproteins exert their oncogenicity in esophageal and tongue squamous cell carcinoma cell lines distinctly

    Article • November 2019, Research Square

    Professor Paul KS Chan

  36. Review article: fungal alterations in inflammatory bowel diseases

    Article • Alimentary Pharmacology & Therapeutics, October 2019, Wiley

    Professor Paul KS Chan

  37. Human papillomavirus type 18 oncoproteins exert their oncogenicity in esophageal and tongue squamous cell carcinoma cell lines distinctly

    Article • September 2019, Research Square

    Professor Paul KS Chan

  38. Impact of Preservation Method and 16S rRNA Hypervariable Region on Gut Microbiota Profiling

    Article • mSystems, February 2019, ASM Journals

    Professor Paul KS Chan, Professor Martin CS Wong

  39. Role of polycyclic aromatic hydrocarbons as a co-factor in human papillomavirus-mediated carcinogenesis

    Article • BMC Cancer, February 2019, Springer Science + Business Media

    Professor Paul KS Chan

  40. Optimal gender-specific age for cost-effective vaccination with adjuvanted herpes zoster subunit vaccine in Chinese adults

    Article • PLoS ONE, January 2019, PLOS

    Professor Paul KS Chan

  41. Complete Genome Sequences of Six Novel Macaca mulatta Papillomavirus Types Isolated from Genital Sites of Rhesus Monkeys in Hong Kong SAR, China

    Article • Microbiology Resource Announcements, December 2018, ASM Journals

    Professor Paul KS Chan

  42. Niche adaptation and viral transmission of human papillomaviruses from archaic hominins to modern humans

    Article • PLoS Pathogens, November 2018, PLOS

    Professor Paul KS Chan

  43. Diversity of macaque microbiota compared to the human counterparts

    Article • Scientific Reports, October 2018, Springer Science + Business Media

    Professor Paul KS Chan

  44. Gut fungal dysbiosis correlates with reduced efficacy of fecal microbiota transplantation in Clostridium difficile infection

    Article • Nature Communications, September 2018, Springer Science + Business Media

    Professor Paul KS Chan

  45. Alterations in Enteric Virome Are Associated With Colorectal Cancer and Survival Outcomes

    Article • Gastroenterology, August 2018, Elsevier

    Professor Martin CS Wong, Professor Paul KS Chan

  46. Potential cost-effectiveness of adjuvanted herpes zoster subunit vaccine for older adults in Hong Kong

    Article • Vaccine, July 2018, Elsevier

    Professor Paul KS Chan

  47. Influenza vaccine effectiveness in hospitalised Hong Kong children: Feasibility of estimates from routine surveillance data

    Article • Vaccine, June 2018, Elsevier

    Professor Paul KS Chan

  48. Three decades of neonatal vaccination has greatly reduced antenatal prevalence of hepatitis B virus infection among gravidae covered by the program

    Article • Journal of Infection, June 2018, Elsevier

    Professor Paul KS Chan

  49. Age-specific seroprevalence of dengue infection in Hong Kong

    Article • Journal of Medical Virology, May 2018, Wiley

    Professor Paul KS Chan

  50. Prevalence and Epidemiologic Profile of Oral Infection with Alpha, Beta, and Gamma Papillomaviruses in an Asian Chinese Population

    Article • The Journal of Infectious Diseases, March 2018, Oxford University Press (OUP)

    Professor Martin CS Wong, Professor Paul KS Chan

  51. Classification and evolution of human papillomavirus genome variants: Alpha-5 (HPV26, 51, 69, 82), Alpha-6 (HPV30, 53, 56, 66), Alpha-11 (HPV34, 73), Alpha-13 (HPV54) and Alpha-3 (HPV61)

    Article • Virology, March 2018, Elsevier

    Professor Paul KS Chan

  52. The role of adjuvant immunomodulatory agents for treatment of severe influenza

    Article • Antiviral Research, February 2018, Elsevier

    Professor Paul KS Chan

  53. Avian influenza A (H7N9) virus infections in humans across five epidemics in mainland China, 2013–2017

    Article • Journal of Thoracic Disease, December 2017, AME Publishing Company

    Professor Paul KS Chan

  54. Complete Genome Sequence of a Novel Human Papillomavirus Isolated from Oral Rinse

    Article • Genome Announcements, November 2017, ASM Journals

    Professor Paul KS Chan, Professor Martin CS Wong

  55. Increased Detection of Emergent Recombinant Norovirus GII.P16-GII.2 Strains in Young Adults, Hong Kong, China, 2016–2017

    Article • Emerging Infectious Diseases, November 2017, Centers for Disease Control and Prevention (CDC)

    Professor Paul KS Chan

  56. Clinical features and seasonality of parechovirus infection in an Asian subtropical city, Hong Kong

    Article • PLoS ONE, September 2017, PLOS

    Professor Paul KS Chan

  57. First-In-Class Inhibitor of Ribosomal RNA Synthesis with Antimicrobial Activity against Staphylococcus aureus

    Article • Biochemistry, August 2017, American Chemical Society (ACS)

    Professor Paul KS Chan

  58. Ancient Evolution and Dispersion of Human Papillomavirus 58 Variants

    Article • Journal of Virology, August 2017, ASM Journals

    Professor Paul KS Chan

  59. Anti-inflammatory effects of adjunctive macrolide treatment in adults hospitalized with influenza: A randomized controlled trial

    Article • Antiviral Research, August 2017, Elsevier

    Professor Paul KS Chan, Wilson Tam

  60. Global Spread of Norovirus GII.17 Kawasaki 308, 2014–2016

    Article • Emerging Infectious Diseases, August 2017, Centers for Disease Control and Prevention (CDC)

    Professor Paul KS Chan

  61. A clinical approach to the threat of emerging influenza viruses in the Asia-Pacific region

    Article • Respirology, July 2017, Wiley

    Professor Paul KS Chan

  62. Epidemiology and clinical analysis of critical patients with child maltreatment admitted to the intensive care units

    Article • Medicine, June 2017, Wolters Kluwer Health

    Professor Paul KS Chan

  63. School-based surveillance for influenza vaccine effectiveness during 2014-2015 seasons in Hong Kong

    Article • Influenza and Other Respiratory Viruses, May 2017, Wiley

    Professor Paul KS Chan

  64. Bacteriophage transfer during faecal microbiota transplantation in Clostridium difficile infection is associated with treatment outcome

    Article • Gut, May 2017, BMJ

    Professor Paul KS Chan

  65. Hepatitis B infection acquired after haematopioetic stem cell transplant through horizontal mode

    Article • Journal of Medical Virology, May 2017, Wiley

    Professor Paul KS Chan, CHi-kong Li

  66. Complete Genome Sequence of an Emergent Recombinant GII.P16-GII.2 Norovirus Strain Associated with an Epidemic Spread in the Winter of 2016-2017 in Hong Kong, China

    Article • Genome Announcements, May 2017, ASM Journals

    Professor Paul KS Chan

  67. IFITM3, TLR3, and CD55 Gene SNPs and Cumulative Genetic Risks for Severe Outcomes in Chinese Patients With H7N9/H1N1pdm09 Influenza

    Article • The Journal of Infectious Diseases, May 2017, Oxford University Press (OUP)

    Professor Paul KS Chan

  68. Exendin-4 Exhibits Enhanced Anti-tumor Effects in Diabetic Mice

    Article • Scientific Reports, May 2017, Springer Science + Business Media

    Professor Paul KS Chan

  69. Molecular Epidemiology and Strain Comparison between Hepatitis E Viruses in Human Sera and Pig Livers during 2014 to 2016 in Hong Kong

    Article • Journal of Clinical Microbiology, February 2017, ASM Journals

    Professor Paul KS Chan

  70. Analysis of Sequence Variation and Risk Association of Human Papillomavirus 52 Variants Circulating in Korea

    Article • PLoS ONE, December 2016, PLOS

    Professor Paul KS Chan

  71. Recurrent Infections of Emergent Norovirus GII.17 in an Elderly

    Article • Clinical Infectious Diseases, December 2016, Oxford University Press (OUP)

    Professor Paul KS Chan

  72. Increased Growth of a Newly Established Mouse Epithelial Cell Line Transformed with HPV-16 E7 in Diabetic Mice

    Article • PLoS ONE, October 2016, PLOS

    Professor Paul KS Chan

  73. 10.1016/j.vaccine.2016.08.047

    Article • Journal of Critical Care, September 2016, Elsevier

    Professor Paul KS Chan

  74. Editorial

    Article • Journal of Virological Methods, September 2016, Elsevier

    Professor Paul KS Chan

  75. Rotavirus vaccine effectiveness in Hong Kong children

    Article • Vaccine, September 2016, Elsevier

    Professor Paul KS Chan

  76. Virological response to peramivir treatment in adults hospitalised for influenza-associated lower respiratory tract infections

    Article • International Journal of Antimicrobial Agents, August 2016, Elsevier

    Professor Paul KS Chan, Fanny Ko, Wilson Tam

  77. Ad Hoc Influenza Vaccination During Years of Significant Antigenic Drift in a Tropical City With 2 Seasonal Peaks

    Article • Medicine, May 2016, Wolters Kluwer Health

    Professor Paul KS Chan, Samuel Wong, Professor Martin CS Wong

  78. Outcome of Encephalitis in Pediatric Intensive Care Unit

    Article • The Indian Journal of Pediatrics, April 2016, Springer Science + Business Media

    Professor Paul KS Chan

  79. Paramyxovirus Infection: Mortality and Morbidity in a Pediatric Intensive Care Unit

    Article • Journal of Tropical Pediatrics, April 2016, Oxford University Press (OUP)

    Professor Paul KS Chan

  80. Reduced Diagnostic Performance of Two Norovirus Antigen Enzyme Immunoassays for the Emergent Genogroup II Genotype 17 Kawasaki 2014 Variant

    Article • Journal of Clinical Microbiology, March 2016, ASM Journals

    Professor Paul KS Chan

  81. Global Genomic Diversity of Human Papillomavirus 11 Based on 433 Isolates and 78 Complete Genome Sequences

    Article • Journal of Virology, March 2016, ASM Journals

    Professor Mario Poljak, Professor Paul KS Chan

  82. Antigen Production in Plant to Tackle Infectious Diseases Flare Up: The Case of SARS

    Article • Frontiers in Plant Science, February 2016, Frontiers

    Professor Paul KS Chan

  83. Rapid emergence and predominance of a broadly recognizing and fast-evolving norovirus GII.17 variant in late 2014

    Article • Nature Communications, December 2015, Nature

    Professor Paul KS Chan

  84. Prevalence, Clinicopathological Characteristics, and Outcome of Human Papillomavirus-Associated Oropharyngeal Cancer in Southern Chinese Patients

    Article • Cancer Epidemiology Biomarkers & Prevention, November 2015, American Association for Cancer Research (AACR)

    Professor Paul KS Chan

  85. Complete Genome Sequence of a Novel Recombinant GII.Pe_GII.17 Norovirus Strain from Hong Kong in 2015

    Article • Genome Announcements, November 2015, ASM Journals

    Professor Paul KS Chan

  86. The role of human papillomavirus in head and neck squamous cell carcinoma: A case control study on a southern Chinese population

    Article • Journal of Medical Virology, November 2015, Wiley

    Professor Paul KS Chan

  87. Hospitalization Incidence, Mortality, and Seasonality of Common Respiratory Viruses Over a Period of 15 Years in a Developed Subtropical City

    Article • Medicine, November 2015, Wolters Kluwer Health

    Professor Paul KS Chan, Professor Martin CS Wong, Wilson Tam

  88. A home-school-doctor model to break the barriers for uptake of human papillomavirus vaccine

    Article • BMC Public Health, September 2015, Springer Science + Business Media

    Professor Paul KS Chan, Professor Martin CS Wong

  89. Update in Viral Infections 2014

    Article • American Review of Respiratory Disease, September 2015, American Thoracic Society

    Professor Paul KS Chan

  90. Parental Attitudes and Factors Associated With Varicella Vaccination in Preschool and Schoolchildren in Hong Kong

    Article • Medicine, September 2015, Wolters Kluwer Health

    Professor Paul KS Chan, Wilson Tam

  91. False-positive PCR detection of cyclovirus Malawi strain VS5700009 in human cerebrospinal fluid

    Article • Journal of Clinical Virology, July 2015, Elsevier

    Professor Paul KS Chan

  92. Virus Genotype Distribution and Virus Burden in Children and Adults Hospitalized for Norovirus Gastroenteritis, 2012–2014, Hong Kong

    Article • Scientific Reports, June 2015, Springer Science + Business Media

    Professor Paul KS Chan

  93. High Viral Load and Respiratory Failure in Adults Hospitalized for Respiratory Syncytial Virus Infections

    Article • The Journal of Infectious Diseases, April 2015, Oxford University Press (OUP)

    Professor Paul KS Chan

  94. Prognostic Implication of Human Papillomavirus Types and Species in Cervical Cancer Patients Undergoing Primary Treatment

    Article • PLoS ONE, April 2015, PLOS

    Professor Paul KS Chan

  95. Cost-effectiveness of quadrivalent influenza vaccine in Hong Kong – A decision analysis

    Article • Human Vaccines & Immunotherapeutics, February 2015, Taylor & Francis

    Professor Paul KS Chan

  96. Genomic aberrations in cervical adenocarcinomas in Hong Kong Chinese women

    Article • International Journal of Cancer, February 2015, Wiley

    Professor Paul KS Chan

  97. Evaluation of the Impact of Human Papillomavirus DNA Self-sampling on the Uptake of Cervical Cancer Screening

    Article • Cancer Nursing, February 2015, Wolters Kluwer Health

    Professor Paul KS Chan, Samuel Wong

  98. influenza, respiratory syncytial virus, antivirals

    Article • European Respiratory Journal, January 2015, European Respiratory Society (ERS)

    Professor Paul KS Chan, Nelson Lee, Wilson Tam

  99. miR-466 is putative negative regulator of Coxsackie virus and Adenovirus Receptor

    Article • FEBS Letters, December 2014, Wiley

    Professor Paul KS Chan

  100. Cost-effectiveness analysis of quadrivalent influenza vaccine versus trivalent influenza vaccine for elderly in Hong Kong

    Article • BMC Infectious Diseases, November 2014, Springer Science + Business Media

    Professor Paul KS Chan

  101. Burden of influenza infection in hospitalised children below 6 months of age and above in Hong Kong from 2005 to 2011

    Article • Vaccine, November 2014, Elsevier

    Professor Paul KS Chan, Professor Margaret Ip

  102. Meta-Analysis on Prevalence and Attribution of Human Papillomavirus Types 52 and 58 in Cervical Neoplasia Worldwide

    Article • PLoS ONE, September 2014, PLOS

    Professor Paul KS Chan, Professor Martin CS Wong

  103. Response to Booster Doses of Hepatitis B Vaccine among Young Adults Who Had Received Neonatal Vaccination

    Article • PLoS ONE, September 2014, PLOS

    Professor Paul KS Chan, Professor Martin CS Wong

  104. Photodynamic inactivation of bacteria and viruses using two monosubstituted zinc(II) phthalocyanines

    Article • European Journal of Medicinal Chemistry, September 2014, Elsevier

    Professor Paul KS Chan

  105. Initial Radiographic Features as Outcome Predictor of Adult Respiratory Syncytial Virus Respiratory Tract Infection

    Article • American Journal of Roentgenology, August 2014, American Roentgen Ray Society

    Professor Paul KS Chan

  106. Typical or atypical pneumonia and severe acute respiratory symptoms in PICU

    Article • The Clinical Respiratory Journal, June 2014, Wiley

    Professor Margaret Ip, Professor Paul KS Chan

  107. Geographical Distribution and Risk Association of Human Papillomavirus Genotype 52–Variant Lineages

    Article • The Journal of Infectious Diseases, May 2014, Oxford University Press (OUP)

    Professor Paul KS Chan, Professor Martin CS Wong

  108. Oligolysine-Conjugated Zinc(II) Phthalocyanines as Efficient Photosensitizers for Antimicrobial Photodynamic Therapy

    Article • Chemistry - An Asian Journal, May 2014, Wiley

    Professor Paul KS Chan

  109. Global Genomic Diversity of Human Papillomavirus 6 Based on 724 Isolates and 190 Complete Genome Sequences

    Article • Journal of Virology, April 2014, ASM Journals

    Professor Eduardo L Franco, Professor Paul KS Chan, Riaz Seedat

  110. Characteristics of Patients Infected with Norovirus GII.4 Sydney 2012, Hong Kong, China

    Article • Emerging Infectious Diseases, April 2014, Centers for Disease Control and Prevention (CDC)

    Professor Paul KS Chan

  111. Characteristics of Patients Infected with Norovirus GII.4 Sydney 2012, Hong Kong, China

    Article • Emerging Infectious Diseases, April 2014, Centers for Disease Control and Prevention (CDC)

    Professor Paul KS Chan

  112. Rotavirus incidence in hospitalised Hong Kong children: 1 July 1997 to 31 March 2011

    Article • Vaccine, March 2014, Elsevier

    Professor Margaret Ip, Professor Paul KS Chan

  113. Recognizing true H5N1 infections in humans during confirmed outbreaks

    Article • The Journal of Infection in Developing Countries, February 2014, Journal of Infection in Developing Countries

    Professor Paul KS Chan

  114. Selection of Referent Transcript for Normalization of Gene Expression in Cervical Cytology Samples

    Article • Applied Immunohistochemistry & Molecular Morphology, February 2014, Wolters Kluwer Health

    Professor Paul KS Chan

  115. Conformationally locked bicyclo[4.3.0]nonane carbanucleosides: synthesis and bio-evaluation

    Article • Organic & Biomolecular Chemistry, January 2014, Royal Society of Chemistry

    Professor Paul KS Chan

  116. Bench to Bed Evidences for Pharmacokinetic and Pharmacodynamic Interactions Involving Oseltamivir and Chinese Medicine

    Article • Evidence-based Complementary and Alternative Medicine, January 2014, Hindawi Publishing Corporation

    Professor Paul KS Chan

  117. Influenza Rapid Test

    Article • Journal of Clinical Microbiology, November 2013, ASM Journals

    Professor Paul KS Chan

  118. Virological characteristics of cervical cancers carrying pure episomal form of HPV16 genome

    Article • Gynecologic Oncology, November 2013, Elsevier

    Professor Paul KS Chan

  119. Controlling novel avian influenza A (H7N9) at animal sources

    Article • BMJ, September 2013, BMJ

    Professor Paul KS Chan

  120. A Prospective Intervention Study on Higher-Dose Oseltamivir Treatment in Adults Hospitalized With Influenza A and B Infections

    Article • Clinical Infectious Diseases, September 2013, Oxford University Press (OUP)

    Professor Paul KS Chan, Wilson Tam

  121. Knowledge, Attitude, Practice and Barriers on Vaccination against Human Papillomavirus Infection: A Cross-Sectional Study among Primary Care Physicians in Hong Kong

    Article • PLoS ONE, August 2013, PLOS

    Professor Paul KS Chan, Professor Martin CS Wong

  122. High Morbidity and Mortality in Adults Hospitalized for Respiratory Syncytial Virus Infections

    Article • Clinical Infectious Diseases, July 2013, Oxford University Press (OUP)

    Professor Paul KS Chan

  123. Rotavirus activity and meteorological variations in an Asian subtropical city, Hong Kong, 1995-2009

    Article • Journal of Medical Virology, July 2013, Wiley

    Professor Paul KS Chan, Wilson Tam

  124. Risk factors for drug-resistant bacterial pneumonia in older patients hospitalized with pneumonia in a Chinese population

    Article • QJM, July 2013, Oxford University Press (OUP)

    Professor Paul KS Chan

  125. Enterovirus infection among patients admitted to hospital in Hong Kong in 2010: Epidemiology, clinical characteristics, and importance of molecular diagnosis

    Article • Journal of Medical Virology, July 2013, Wiley

    Professor Paul KS Chan

  126. A pilot randomized study to assess immunogenicity, reactogenicity, safety and tolerability of two human papillomavirus vaccines administered intramuscularly and intradermally to females aged 18–26 years

    Article • Vaccine, July 2013, Elsevier

    Professor Paul KS Chan, Dr Hugh Simon Lam

  127. Replication and Transcription Activities of Ribonucleoprotein Complexes Reconstituted from Avian H5N1, H1N1pdm09 and H3N2 Influenza A Viruses

    Article • PLoS ONE, June 2013, PLOS

    Professor Paul KS Chan

  128. Increased nasopharyngeal carriage of serotypes 6A, 6C, and 6D Streptococcus pneumoniae after introduction of childhood pneumococcal vaccination in Hong Kong

    Article • Diagnostic Microbiology and Infectious Disease, June 2013, Elsevier

    Professor Margaret Ip, Professor Paul KS Chan

  129. Adjunctive therapies and immunomodulatory agents in the management of severe influenza

    Article • Antiviral Research, June 2013, Elsevier

    Professor Paul KS Chan

  130. Anti-inflammatory effects of exendin-4, a glucagon-like peptide-1 analog, on human peripheral lymphocytes in patients with type 2 diabetes

    Article • Journal of Diabetes Investigation, April 2013, Wiley

    Professor Paul KS Chan

  131. Indirect Immunofluorescence Assay for the Simultaneous Detection of Antibodies against Clinically Important Old and New World Hantaviruses

    Article • PLoS Neglected Tropical Diseases, April 2013, PLOS

    Professor Paul KS Chan

  132. Efficacy, safety and immunogenicity of a human rotavirus vaccine (RIX4414) in Hong Kong children up to three years of age: A randomized, controlled trial

    Article • Vaccine, April 2013, Elsevier

    Professor Paul KS Chan, Dr Tsz Leung Lee

  133. Role of human Toll-like receptors in naturally occurring influenza A infections

    Article • Influenza and Other Respiratory Viruses, April 2013, Wiley

    Professor Paul KS Chan

  134. A “pre-seasonal” hospital outbreak of influenza pneumonia caused by the drift variant A/Victoria/361/2011-like H3N2 viruses, Hong Kong, 2011

    Article • Journal of Clinical Virology, March 2013, Elsevier

    Professor Paul KS Chan

  135. Early detection of nasopharyngeal carcinoma by plasma Epstein-Barr virus DNA analysis in a surveillance program

    Article • Cancer, February 2013, Wiley

    Professor Paul KS Chan

  136. Role of Atypical Pathogens in Nursing Home–Acquired Pneumonia

    Article • Journal of the American Medical Directors Association, February 2013, Elsevier

    Professor Margaret Ip, Professor Jean Woo, Professor Paul KS Chan

  137. Effect of avian influenza A H5N1 infection on the expression of microRNA-141 in human respiratory epithelial cells

    Article • BMC Microbiology, January 2013, Springer Science + Business Media

    Professor Paul KS Chan

  138. Immunization of N terminus of enterovirus 71 VP4 elicits cross-protective antibody responses

    Article • BMC Microbiology, January 2013, Springer Science + Business Media

    Professor Paul KS Chan

  139. Seroprevalence of hepatitis E virus in Hong Kong, 2008-2009

    Article • Journal of Medical Virology, December 2012, Wiley

    Professor Paul KS Chan

  140. Relationship between age and prevalence of hepatitis B infection in first-year university students in Hong Kong

    Article • Infection, December 2012, Springer Science + Business Media

    Professor Paul KS Chan

  141. Impact of neonatal hepatitis B vaccination programme on age-specific prevalence of hepatitis B infection in teenage mothers in Hong Kong

    Article • Epidemiology and Infection, December 2012, Cambridge University Press

    Professor Paul KS Chan

  142. Geographical distribution and oncogenic risk association of human papillomavirus type 58 E6 and E7 sequence variations

    Article • International Journal of Cancer, November 2012, Wiley

    Professor Paul KS Chan, Professor Martin CS Wong

  143. Influenza B Lineage Circulation and Hospitalization Rates in a Subtropical City, Hong Kong, 2000-2010

    Article • Clinical Infectious Diseases, October 2012, Oxford University Press (OUP)

    Professor Paul KS Chan, Professor Martin CS Wong

  144. Respiratory syncytial virus morbidity, premorbid factors, seasonality, and implications for prophylaxis

    Article • Journal of Critical Care, October 2012, Elsevier

    Professor Paul KS Chan

  145. Determinants of Antiviral Effectiveness in Influenza Virus A Subtype H5N1

    Article • The Journal of Infectious Diseases, August 2012, Oxford University Press (OUP)

    Professor Paul KS Chan

  146. Laboratory and clinical aspects of human papillomavirus testing

    Article • Critical Reviews in Clinical Laboratory Sciences, August 2012, Taylor & Francis

    Professor Paul KS Chan

  147. Intact Survival of Refractory CMV Limbic Encephalitis in a Patient With Severe Aplastic Anemia After Unrelated Bone Marrow Transplantation

    Article • Journal of Pediatric Hematology/Oncology, August 2012, Wolters Kluwer Health

    Professor Paul KS Chan

  148. Intestinal binding of seasonal influenza A viruses to DC-SIGN+CD68+cells

    Article • Influenza and Other Respiratory Viruses, July 2012, Wiley

    Professor Paul KS Chan

  149. Chronic psychosocial stress: does it modulate immunity to the influenza vaccine in Hong Kong Chinese elderly caregivers?

    Article • AGE, July 2012, Springer Science + Business Media

    Professor Jean Woo, Professor Paul KS Chan

  150. Transvaginal ultrasound probe contamination by the human papillomavirus in the emergency department

    Article • Emergency Medicine Journal, July 2012, BMJ

    Professor Paul KS Chan

  151. Comparisons of oseltamivir-resistant (H275Y) and concurrent oseltamivir-susceptible seasonal influenza A(H1N1) virus infections in hospitalized adults, 2008-2009

    Article • Influenza and Other Respiratory Viruses, June 2012, Wiley

    Professor Paul KS Chan

  152. Differences in the compliance with hospital infection control practices during the 2009 influenza H1N1 pandemic in three countries

    Article • Journal of Hospital Infection, June 2012, Elsevier

    Professor Paul KS Chan

  153. Influenza Polymerase Activity Correlates with the Strength of Interaction between Nucleoprotein and PB2 through the Host-Specific Residue K/E627

    Article • PLoS ONE, May 2012, PLOS

    Professor Paul KS Chan

  154. Structural Basis for RNA Binding and Homo-Oligomer Formation by Influenza B Virus Nucleoprotein

    Article • Journal of Virology, April 2012, ASM Journals

    Professor Paul KS Chan

  155. H5N1 Avian Influenza in Children

    Article • Clinical Infectious Diseases, March 2012, Oxford University Press (OUP)

    Professor Paul KS Chan

  156. Human papillomavirus type 58: the unique role in cervical cancers in East Asia

    Article • Cell & Bioscience, January 2012, Springer Science + Business Media

    Professor Paul KS Chan

  157. Inaccurate identification of rotavirus genotype G9 as genotype G3 strains due to primer mismatch

    Article • Virology Journal, January 2012, Springer Science + Business Media

    Professor Paul KS Chan

  158. Antagonist-mediated down-regulation of toll-like receptors increases the prevalence of human papillomavirus infection in systemic lupus erythematosus

    Article • Arthritis Research & Therapy, January 2012, Springer Science + Business Media

    Professor Paul KS Chan, Professor Martin CS Wong

  159. Familial aggregation of narcolepsy

    Article • Sleep Medicine, December 2011, Elsevier

    Professor Paul KS Chan

  160. Seasonal Influenza A Virus in Feces of Hospitalized Adults

    Article • November 2011, Centers for Disease Control and Prevention (CDC)

    Professor Paul KS Chan

  161. Cytokine Response Patterns in Severe Pandemic 2009 H1N1 and Seasonal Influenza among Hospitalized Adults

    Article • PLoS ONE, October 2011, PLOS

    Professor Paul KS Chan

  162. Attribution of human papillomavirus types to cervical intraepithelial neoplasia and invasive cancers in Southern China

    Article • International Journal of Cancer, October 2011, Wiley

    Professor Paul KS Chan

  163. Seasonal influenza vaccination predicts pandemic H1N1 vaccination uptake among healthcare workers in three countries

    Article • Vaccine, October 2011, Elsevier

    Professor Paul KS Chan

  164. Seroprevalence of varicella zoster virus among pregnant women in Hong Kong: Comparison with self-reported history

    Article • Vaccine, October 2011, Elsevier

    Professor Paul KS Chan

  165. A Possible Geographic Origin of Endemic Hepatitis C Virus 6a in Hong Kong: Evidences for the Association with Vietnamese Immigration

    Article • PLoS ONE, September 2011, PLOS

    Professor Paul KS Chan

  166. Clinical Spectrum of Human Rhinovirus Infections in Hospitalized Hong Kong Children

    Article • The Pediatric Infectious Disease Journal, September 2011, Wolters Kluwer Health

    Professor Paul KS Chan

  167. Strengthening Observational Evidence for Antiviral Effectiveness in Influenza A (H5N1)

    Article • The Journal of Infectious Diseases, August 2011, Oxford University Press (OUP)

    Professor Paul KS Chan

  168. Prevalence of human papillomavirus, Epstein-Barr virus, p21, and p53 expression in sinonasal inverted papilloma, nasal polyp, and hypertrophied turbinate in Hong Kong patients

    Article • Head & Neck, May 2011, Wiley

    Professor Paul KS Chan

  169. Complications and Outcomes of Pandemic 2009 Influenza A (H1N1) Virus Infection in Hospitalized Adults: How Do They Differ From Those in Seasonal Influenza?

    Article • The Journal of Infectious Diseases, May 2011, Oxford University Press (OUP)

    Professor Paul KS Chan

  170. Identification of Human Papillomavirus Type 58 Lineages and the Distribution Worldwide

    Article • The Journal of Infectious Diseases, May 2011, Oxford University Press (OUP)

    Professor Paul KS Chan

  171. Non-invasive screening of HLA-DPA1 and HLA-DPB1 alleles for persistent hepatitis B virus infection: Susceptibility for vertical transmission and toward a personalized approach for vaccination and treatment

    Article • Clinica Chimica Acta, May 2011, Elsevier

    Professor Paul KS Chan

  172. T-cell response to human papillomavirus type 52 L1, E6, and E7 peptides in women with transient infection, cervical intraepithelial neoplasia, and invasive cancer

    Article • Journal of Medical Virology, April 2011, Wiley

    Professor Paul KS Chan

  173. Pandemic (H1N1) 2009 vaccine in paediatric oncology patients: one dose or two doses?

    Article • British Journal of Haematology, April 2011, Wiley

    Professor Paul KS Chan

  174. Clinical and virological course of infection with haemagglutinin D222G mutant strain of 2009 pandemic influenza A (H1N1) virus

    Article • Journal of Clinical Virology, April 2011, Elsevier

    Professor Paul KS Chan

  175. Inhibition of severe acute respiratory syndrome coronavirus replication in a lethal SARS-CoV BALB/c mouse model by stinging nettle lectin, Urtica dioica agglutinin

    Article • Antiviral Research, April 2011, Elsevier

    Professor Paul KS Chan

  176. Co-dominance of G1 and emerging G3 rotaviruses in Hong Kong: A three-year surveillance in three major hospitals

    Article • Journal of Clinical Virology, April 2011, Elsevier

    Professor Paul KS Chan

  177. Novel therapeutic potential in targeting microtubules by nanoparticle albumin-bound paclitaxel in hepatocellular carcinoma

    Article • International Journal of Oncology, March 2011, Spandidos Publications

    Professor Paul KS Chan

  178. Risk factors for squamous intraepithelial lesions in systemic lupus erythematosus: A prospective cohort study

    Article • Arthritis Care & Research, January 2011, Wiley

    Professor Paul KS Chan, Professor Martin CS Wong

  179. Apoptosis, cytokine and chemokine induction by non-structural 1 (NS1) proteins encoded by different influenza subtypes

    Article • Virology Journal, January 2011, Springer Science + Business Media

    Professor Paul KS Chan

  180. Polymerase activity of hybrid ribonucleoprotein complexes generated from reassortment between 2009 pandemic H1N1 and seasonal H3N2 influenza A viruses

    Article • Virology Journal, January 2011, Springer Science + Business Media

    Professor Paul KS Chan

  181. Viral clearance and inflammatory response patterns in adults hospitalized for pandemic 2009 influenza A(H1N1) virus pneumonia

    Article • Antiviral Therapy, January 2011, International Medical Press

    Professor Paul KS Chan

  182. Mutations around interferon sensitivity-determining region: A pilot resistance report of hepatitis C virus 1b in a Hong Kong population

    Article • World Journal of Gastroenterology, January 2011, Baishideng Publishing Group Co., Limited (formerly WJG Press)

    Professor Paul KS Chan

  183. Possible Role of Aerosol Transmission in a Hospital Outbreak of Influenza

    Article • Clinical Infectious Diseases, November 2010, Oxford University Press (OUP)

    Professor Paul KS Chan

  184. Willingness to accept H1N1 pandemic influenza vaccine: A cross-sectional study of Hong Kong community nurses

    Article • BMC Infectious Diseases, October 2010, Springer Science + Business Media

    Professor Paul KS Chan, Samuel Wong

  185. Effectiveness of Antiviral Treatment in Human Influenza A(H5N1) Infections: Analysis of a Global Patient Registry

    Article • The Journal of Infectious Diseases, October 2010, Oxford University Press (OUP)

    Professor Paul KS Chan

  186. Sequence diversity of hepatitis C virus 6a within the extended interferon sensitivity-determining region correlates with interferon-alpha/ribavirin treatment outcomes

    Article • Virus Research, October 2010, Elsevier

    Professor Paul KS Chan

  187. Influenza and Parainfluenza Associated Pediatric ICU Morbidity

    Article • The Indian Journal of Pediatrics, September 2010, Springer Science + Business Media

    Professor Paul KS Chan

  188. Severe Acute Respiratory Syndrome and Coronavirus

    Article • Infectious Disease Clinics of North America, September 2010, Elsevier

    Professor Paul KS Chan

  189. An unusual cluster of HIV-1 B/F recombinants in an Asian population

    Article • International Journal of Infectious Diseases, September 2010, Elsevier

    Professor Paul KS Chan

  190. Prevalence and genotype distribution of cervical human papillomavirus infection in Macao

    Article • Journal of Medical Virology, September 2010, Wiley

    Professor Paul KS Chan

  191. Lymphoproliferative response to herpes simplex virus type 1, cytomegalovirus, Epstein-Barr virus, varicella zoster virus, human herpes virus 6, 7, and 8 antigen stimulation in pediatric allogeneic stem cell transplant recipients

    Article • Pediatric Transplantation, August 2010, Wiley

    Professor Paul KS Chan

  192. T-Cell Response to Human Papillomavirus Type 58 L1, E6, and E7 Peptides in Women with Cleared Infection, Cervical Intraepithelial Neoplasia, or Invasive Cancer

    Article • Clinical and Vaccine Immunology, July 2010, ASM Journals

    Professor Paul KS Chan

  193. Distribution of human papillomavirus genotypes among cervical intraepithelial neoplasia and invasive cancers in Macao

    Article • Journal of Medical Virology, July 2010, Wiley

    Professor Paul KS Chan

  194. Monitoring of perceptions, anticipated behavioral, and psychological responses related to H5N1 influenza

    Article • Infection, June 2010, Springer Science + Business Media

    Professor Paul KS Chan, Prof Jean H Kim

  195. Allele-specific conventional reverse-transcription polymerase chain reaction as a screening assay for discriminating influenza a H1N1 (H275Y) oseltamivir-resistant and wild-type viruses

    Article • Journal of Medical Virology, June 2010, Wiley

    Professor Paul KS Chan

  196. Outcomes of adults hospitalised with severe influenza

    Article • Thorax, June 2010, BMJ

    Professor Paul KS Chan

  197. Functional Analysis of the Influenza Virus H5N1 Nucleoprotein Tail Loop Reveals Amino Acids That Are Crucial for Oligomerization and Ribonucleoprotein Activities

    Article • Journal of Virology, May 2010, ASM Journals

    Professor Paul KS Chan

  198. HHV-6 encephalitis in pediatric unrelated umbilical cord transplantation: A role for ganciclovir prophylaxis?

    Article • Pediatric Transplantation, May 2010, Wiley

    Professor Paul KS Chan

  199. Co-infection With Pandemic H1N1 and Seasonal H3N2 Influenza Viruses

    Article • Annals of Internal Medicine, May 2010, American College of Physicians

    Professor Paul KS Chan

  200. Survey for the presence of BK, JC, KI, WU and Merkel cell polyomaviruses in human brain tissues

    Article • Journal of Clinical Virology, May 2010, Elsevier

    Professor Paul KS Chan

  201. CFTR is required for cellular entry and internalization ofChlamydia trachomatis

    Article • Cell Biology International, April 2010, Wiley

    Professor Paul KS Chan, Dr Ellis Fok

  202. RECOVERY OF HUMORAL AND CELLULAR IMMUNITIES TO VACCINE-PREVENTABLE INFECTIOUS DISEASES IN PEDIATRIC ONCOLOGY PATIENTS

    Article • Pediatric Hematology and Oncology, April 2010, Taylor & Francis

    Professor Paul KS Chan

  203. Clinical Management of Pandemic 2009 Influenza A(H1N1) Infection

    Article • CHEST Journal, April 2010, Elsevier

    Professor Paul KS Chan

  204. Narcissus tazetta lectin shows strong inhibitory effects against respiratory syncytial virus, influenza A (H1N1, H3N2, H5N1) and B viruses

    Article • Journal of Biosciences, February 2010, Springer Science + Business Media

    Professor Paul KS Chan

  205. Development and comparison of molecular assays for the rapid detection of the pandemic influenza A (H1N1) 2009 virus

    Article • Journal of Medical Virology, February 2010, Wiley

    Professor Paul KS Chan

  206. Multiplex Molecular Detection of Respiratory Pathogens in Children With Asthma Exacerbation

    Article • CHEST Journal, February 2010, Elsevier

    Professor Paul KS Chan

  207. Age distribution of human papillomavirus infection and cervical neoplasia reflects caveats of cervical screening policies

    Article • International Journal of Cancer, January 2010, Wiley

    Professor Paul KS Chan

  208. Profiles of cytokine and chemokine gene expression in human pulmonary epithelial cells induced by human and avian influenza viruses

    Article • Virology Journal, January 2010, Springer Science + Business Media

    Professor Paul KS Chan

  209. Two Antifungal Components Isolated from Fructus Psoraleae and Folium Eucalypti Globuli by Bioassay-Guided Purification

    Article • The American Journal of Chinese Medicine, January 2010, World Scientific Pub Co Pte Lt

    Professor Paul KS Chan

  210. Acute Encephalopathy Associated with Influenza A Infection in Adults

    Article • Emerging Infectious Diseases, January 2010, Centers for Disease Control and Prevention (CDC)

    Professor Paul KS Chan

  211. Full Genome Analysis of an Emerging Cluster of Human Immunodeficiency Virus Type 1 Subtype B Infection in Hong Kong

    Article • AIDS Research and Human Retroviruses, January 2010, Mary Ann Liebert Inc

    Professor Paul KS Chan

  212. Acute Encephalopathy Associated with Influenza A Infection in Adults

    Article • Emerging Infectious Diseases, January 2010, Centers for Disease Control and Prevention (CDC)

    Professor Paul KS Chan

  213. Broad-Spectrum In Vitro Activity and In Vivo Efficacy of the Antiviral Protein Griffithsin against Emerging Viruses of the Family Coronaviridae

    Article • Journal of Virology, December 2009, ASM Journals

    Professor Paul KS Chan

  214. Natural History of Cervical Papilloma Virus Infection in Systemic Lupus Erythematosus -- A Prospective Cohort Study

    Article • The Journal of Rheumatology, December 2009, The Journal of Rheumatology

    Professor Paul KS Chan, Professor Martin CS Wong

  215. Use of intravenous fluids in Hong Kong children hospitalised for diarrhoea and relationship to severity and aetiology

    Article • Vaccine, November 2009, Elsevier

    Professor Paul KS Chan

  216. Prevalence of diarrhea viruses in hospitalized children in Hong Kong in 2008

    Article • Journal of Medical Virology, November 2009, Wiley

    Professor Paul KS Chan

  217. Role of ‘atypical pathogens’ among adult hospitalized patients with community‐acquired pneumonia

    Article • Respirology, October 2009, Wiley

    Professor Margaret Ip, Professor Paul KS Chan

  218. Distribution of human papillomavirus types in cervical cancers in Hong Kong: Current situation and changes over the last decades

    Article • International Journal of Cancer, October 2009, Wiley

    Professor Paul KS Chan, Professor Martin CS Wong

  219. Seasonal influenza activity in Hong Kong and its association with meteorological variations

    Article • Journal of Medical Virology, October 2009, Wiley

    Professor Paul KS Chan

  220. Distribution of Human Papillomavirus Type 58 Variants in Progression of Cervical Dysplasia in Korean Women

    Article • Journal of Microbiology and Biotechnology, September 2009, Korean Society for Microbiology and Biotechnology

    Professor Paul KS Chan

  221. Epidemiology and Clinical Presentations of Human Coronavirus NL63 Infections in Hong Kong Children

    Article • Journal of Clinical Microbiology, September 2009, ASM Journals

    Professor Paul KS Chan

  222. Epidemiologic risk profile of infection with different groups of human papillomaviruses

    Article • Journal of Medical Virology, September 2009, Wiley

    Professor Paul KS Chan, Professor Martin CS Wong

  223. Willingness of Hong Kong healthcare workers to accept pre-pandemic influenza vaccination at different WHO alert levels: two questionnaire surveys

    Article • BMJ, August 2009, BMJ

    Professor Paul KS Chan, Samuel Wong, Professor Martin CS Wong

  224. Viral Loads and Duration of Viral Shedding in Adult Patients Hospitalized with Influenza

    Article • The Journal of Infectious Diseases, August 2009, Oxford University Press (OUP)

    Professor Paul KS Chan

  225. Fecal detection of influenza A virus in patients with concurrent respiratory and gastrointestinal symptoms

    Article • Journal of Clinical Virology, July 2009, Elsevier

    Professor Paul KS Chan

  226. Neutralizing monoclonal antibodies to different clades of Influenza A H5N1 viruses

    Article • Journal of Virological Methods, May 2009, Elsevier

    Professor Nigel James Temperton, Professor Paul KS Chan

  227. Genotype Distribution and Sequence Variation of Hepatitis E Virus, Hong Kong

    Article • Emerging Infectious Diseases, May 2009, Centers for Disease Control and Prevention (CDC)

    Professor Paul KS Chan

  228. Molecular epidemiology of hepatitis C genotype 6a from patients with chronic hepatitis C from Hong Kong

    Article • Journal of Medical Virology, April 2009, Wiley

    Professor Paul KS Chan

  229. Distribution of human papillomavirus types in anogenital warts of men

    Article • Journal of Clinical Virology, February 2009, Elsevier

    Professor Paul KS Chan

  230. Humoral immune response after post-chemotherapy booster diphtheria-tetanus-pertussis vaccine in pediatric oncology patients

    Article • Pediatric Blood & Cancer, February 2009, Wiley

    Professor Paul KS Chan

  231. Acceptance of human papillomavirus vaccination among first year female university students in Hong Kong

    Article • Sexual Health, January 2009, CSIRO Publishing

    Professor Paul KS Chan

  232. Hepatitis B Virus Reactivation in Lymphoma Patients With Prior Resolved Hepatitis B Undergoing Anticancer Therapy With or Without Rituximab

    Article • Journal of Clinical Oncology, December 2008, American Society of Clinical Oncology (ASCO)

    Professor Paul KS Chan, Prof Henry LY Chan

  233. A wide spectrum of dengue IgM and PCR positivity post-onset of illness found in a large dengue 3 outbreak in Pakistan

    Article • Journal of Medical Virology, December 2008, Wiley

    Professor Paul KS Chan

  234. Analysis of Human Papillomavirus Type 18 Load and Integration Status from Low-Grade Cervical Lesion to Invasive Cervical Cancer

    Article • Journal of Clinical Microbiology, November 2008, ASM Journals

    Professor Paul KS Chan, Professor Martin CS Wong

  235. Cytokine responses in a severe case of glandular fever treated successfully with foscarnet combined with prednisolone and intravenous immunoglobulin

    Article • Journal of Medical Virology, November 2008, Wiley

    Professor Paul KS Chan

  236. Identification of viral and atypical bacterial pathogens in children hospitalized with acute respiratory infections in Hong Kong by multiplex PCR assays

    Article • Journal of Medical Virology, November 2008, Wiley

    Professor Paul KS Chan

  237. Polymorphisms in the C-type lectin genes cluster in chromosome 19 and predisposition to severe acute respiratory syndrome coronavirus (SARS-CoV) infection

    Article • Journal of Medical Genetics, November 2008, BMJ

    Professor Paul KS Chan

  238. Lack of cross-immune reactivity against influenza H5N1 from seasonal influenza vaccine in humans

    Article • Journal of Medical Virology, November 2008, Wiley

    Professor Paul KS Chan

  239. Involvement of cystic fibrosis transmembrane conductance regulator (CFTR) in the pathogenesis of hydrosalpinx induced by Chlamydia trachomatis infection

    Article • Journal of Obstetrics and Gynaecology Research, October 2008, Wiley

    Professor Paul KS Chan, Dr Ellis Fok

  240. Stockpiling prepandemic influenza vaccines: a new cornerstone of pandemic preparedness plans

    Article • The Lancet Infectious Diseases, October 2008, Elsevier

    Professor Paul KS Chan

  241. Induction of cell cycle arrest and apoptosis by 5-fluorouracil in laryngeal cancer cells containing HPV16 E6 and E7 oncoproteins

    Article • Clinical Biochemistry, October 2008, Elsevier

    Professor Paul KS Chan

  242. Genotypic analysis of two hypervariable human cytomegalovirus genes

    Article • Journal of Medical Virology, September 2008, Wiley

    Professor Paul KS Chan, Professor Vincent Emery

  243. Failure to confirm HIV infection in two end-stage HIV/AIDS patients using a popular commercial line immunoassay

    Article • Journal of Medical Virology, September 2008, Wiley

    Professor Paul KS Chan

  244. A one-year prospective study of infectious etiology in patients hospitalized with acute exacerbations of COPD and concomitant pneumonia

    Article • Respiratory Medicine, August 2008, Elsevier

    Professor Margaret Ip, Professor Paul KS Chan, Fanny Ko

  245. Is the anti-psychotic, 10-(3-(dimethylamino)propyl)phenothiazine (promazine), a potential drug with which to treat SARS infections?

    Article • Antiviral Research, August 2008, Elsevier

    Professor Paul KS Chan

  246. Influenza-like illness in residential care homes: a study of the incidence, aetiological agents, natural history and health resource utilisation

    Article • Thorax, August 2008, BMJ

    Professor Paul KS Chan

  247. Seasonality of Influenza A(H3N2) Virus: A Hong Kong Perspective (1997–2006)

    Article • PLoS ONE, July 2008, PLOS

    Professor Paul KS Chan

  248. Comparative Study of Nasopharyngeal Aspirate and Nasal Swab Specimens for Diagnosis of Acute Viral Respiratory Infection

    Article • Journal of Clinical Microbiology, July 2008, ASM Journals

    Professor Paul KS Chan

  249. Involvement of cystic fibrosis transmembrane conductance regulator in infection-induced edema

    Article • Cell Biology International, July 2008, Wiley

    Professor Paul KS Chan, Dr Ellis Fok

  250. Clearance of dengue virus in the plasma-derived therapeutic proteins

    Article • Transfusion, July 2008, Wiley

    Professor Paul KS Chan

  251. Structure of the influenza virus A H5N1 nucleoprotein: implications for RNA binding, oligomerization, and vaccine design

    Article • The FASEB Journal, June 2008, Federation of American Societies For Experimental Biology (FASEB)

    Professor Paul KS Chan

  252. Clinical features, pathogenesis and immunobiology of severe acute respiratory syndrome

    Article • Current Opinion in Pulmonary Medicine, May 2008, Wolters Kluwer Health

    Professor Paul KS Chan

  253. Pediatric hospitalization of acute respiratory tract infections with Human Bocavirus in Hong Kong

    Article • Journal of Clinical Virology, May 2008, Elsevier

    Professor Paul KS Chan

  254. Antiviral Treatment for Patients Hospitalized with Severe Influenza Infection May Affect Clinical Outcomes

    Article • Clinical Infectious Diseases, April 2008, Oxford University Press (OUP)

    Professor Paul KS Chan

  255. Increase of Integration Events and Infection Loads of Human Papillomavirus Type 52 with Lesion Severity from Low-Grade Cervical Lesion to Invasive Cancer

    Article • Journal of Clinical Microbiology, February 2008, ASM Journals

    Professor Paul KS Chan

  256. Avian Influenza Virus A/HK/483/97(H5N1) NS1 Protein Induces Apoptosis in Human Airway Epithelial Cells

    Article • Journal of Virology, January 2008, ASM Journals

    Professor Paul KS Chan

  257. Thrombopoietin levels increased in patients with severe acute respiratory syndrome

    Article • Thrombosis Research, January 2008, Elsevier

    Professor Paul KS Chan

  258. Development of Human Single-Chain Antibodies against SARS-Associated Coronavirus

    Article • Intervirology, January 2008, Karger Publishers

    Professor Paul KS Chan

  259. Emergence of adamantane-resistant influenza A(H3N2) viruses in Hong Kong between 1997 and 2006

    Article • Journal of Medical Virology, January 2008, Wiley

    Professor Paul KS Chan

  260. Airflow and droplet spreading around oxygen masks: A simulation model for infection control research

    Article • American Journal of Infection Control, December 2007, Elsevier

    Professor Margaret Ip, Professor Paul KS Chan

  261. Co-circulation of human metapneumovirus and SARS-associated coronavirus during a major nosocomial SARS outbreak in Hong Kong

    Article • Journal of Clinical Virology, December 2007, Elsevier

    Professor Paul KS Chan

  262. Evaluation of Epstein-Barr virus antigen-based immunoassays for serological diagnosis of nasopharyngeal carcinoma

    Article • Journal of Clinical Virology, December 2007, Elsevier

    Professor Paul KS Chan

  263. Herpes Labialis

    Article • New England Journal of Medicine, November 2007, New England Journal of Medicine (NEJM/MMS)

    Professor Paul KS Chan

  264. Activation of the JNK pathway promotes phosphorylation and degradation of BimEL--a novel mechanism of chemoresistance in T-cell acute lymphoblastic leukemia

    Article • Carcinogenesis, October 2007, Oxford University Press (OUP)

    Professor Paul KS Chan

  265. High Prevalence of the CD14-159CC Genotype in Patients Infected with Severe Acute Respiratory Syndrome-Associated Coronavirus

    Article • Clinical and Vaccine Immunology, October 2007, ASM Journals

    Professor Paul KS Chan

  266. Value of serum procalcitonin, neopterin, and C-reactive protein in differentiating bacterial from viral etiologies in patients presenting with lower respiratory tract infections

    Article • Diagnostic Microbiology and Infectious Disease, October 2007, Elsevier

    Professor Paul KS Chan

  267. Cytokine Profile in Fatal Human Immunodeficiency Virus–Tuberculosis–Epstein-Barr Virus–Associated Hemophagocytic Syndrome

    Article • Archives of Internal Medicine, September 2007, American Medical Association (AMA)

    Professor Paul KS Chan

  268. Profile of Viral Load, Integration, and E2 Gene Disruption of HPV58 in Normal Cervix and Cervical Neoplasia

    Article • The Journal of Infectious Diseases, September 2007, Oxford University Press (OUP)

    Professor Paul KS Chan

  269. Hypercytokinemia and Hyperactivation of Phospho-p38 Mitogen-Activated Protein Kinase in Severe Human Influenza A Virus Infection

    Article • Clinical Infectious Diseases, September 2007, Oxford University Press (OUP)

    Professor Paul KS Chan

  270. Rapid Multiplex Nested PCR for Detection of Respiratory Viruses

    Article • Journal of Clinical Microbiology, September 2007, ASM Journals

    Professor Paul KS Chan

  271. Viral Etiology of Acute Exacerbations of COPD in Hong Kong

    Article • CHEST Journal, September 2007, Elsevier

    Professor Paul KS Chan, Fanny Ko

  272. Fecal Viral Concentration and Diarrhea in Norovirus Gastroenteritis

    Article • Emerging Infectious Diseases, September 2007, Centers for Disease Control and Prevention (CDC)

    Professor Paul KS Chan

  273. HLA-DQB1 polymorphisms and risk for cervical cancer: A case-control study in a southern Chinese population

    Article • Gynecologic Oncology, June 2007, Elsevier

    Professor Paul KS Chan

  274. Lack of support for an association between CLEC4M homozygosity and protection against SARS coronavirus infection

    Article • Nature Genetics, June 2007, Nature

    Professor Paul KS Chan

  275. Lack of support for an association between CLEC4M homozygosity and protection against SARS coronavirus infection

    Article • Nature Genetics, June 2007, Springer Science + Business Media

    Professor Paul KS Chan

  276. Serotype Distribution and Antimicrobial Susceptibilities of Nasopharyngeal Isolates of Streptococcus pneumoniae from Children Hospitalized for Acute Respiratory Illnesses in Hong Kong

    Article • Journal of Clinical Microbiology, April 2007, ASM Journals

    Professor Paul KS Chan

  277. Longitudinally Tracking Fluoroquinolone Resistance and Its Determinants in Penicillin-Susceptible and -Nonsusceptible Streptococcus pneumoniae Isolates in Hong Kong, 2000 to 2005

    Article • Antimicrobial Agents and Chemotherapy, March 2007, ASM Journals

    Professor Paul KS Chan

  278. Prospective comparison of three predictive rules for assessing severity of community-acquired pneumonia in Hong Kong

    Article • Thorax, January 2007, BMJ

    Professor Paul KS Chan

  279. Features discriminating SARS from other severe viral respiratory tract infections

    Article • European Journal of Clinical Microbiology & Infectious Diseases, January 2007, Springer Science + Business Media

    Professor Paul KS Chan

  280. Streptococcus suis in Hong Kong

    Article • Diagnostic Microbiology and Infectious Disease, January 2007, Elsevier

    Professor Margaret Ip, Professor Paul KS Chan

  281. Characterizing 56 complete SARS-CoV S-gene sequences from Hong Kong

    Article • Journal of Clinical Virology, January 2007, Elsevier

    Professor Margaret Ip, Professor Paul KS Chan

  282. Genetic evolution of enterovirus 71: epidemiological and pathological implications

    Article • Reviews in Medical Virology, January 2007, Wiley

    Professor Paul KS Chan

  283. Association Between HLA-DRB1 polymorphism, high-risk HPV infection and cervical neoplasia in southern Chinese

    Article • Journal of Medical Virology, January 2007, Wiley

    Professor Paul KS Chan

  284. A 1-Year Prospective Study of the Infectious Etiology in Patients Hospitalized With Acute Exacerbations of COPD

    Article • CHEST Journal, January 2007, Elsevier

    Professor Paul KS Chan

  285. Dose-by-dose virological and hematological responses to intravenous immunoglobulin in an immunocompromised patient with persistent parvovirus B19 infection

    Article • Journal of Medical Virology, January 2007, Wiley

    Professor Paul KS Chan

  286. Quantitative temporal-spatial distribution of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) in post-mortem tissues

    Article • Journal of Medical Virology, January 2007, Wiley

    Professor Paul KS Chan

  287. Hepatitis B viral load predicts survival of HCC patients undergoing systemic chemotherapy

    Article • Hepatology, January 2007, Wiley

    Professor Paul KS Chan

  288. Viral Load, E2 Gene Disruption Status, and Lineage of Human Papillomavirus Type 16 Infection in Cervical Neoplasia

    Article • The Journal of Infectious Diseases, December 2006, Oxford University Press (OUP)

    Professor Paul KS Chan

  289. Use of the housekeeping genes, gdh (zwf) and gki, in multilocus sequence typing to differentiate Streptococcus pneumoniae from Streptococcus mitis and Streptococcus oralis

    Article • Diagnostic Microbiology and Infectious Disease, November 2006, Elsevier

    Professor Margaret Ip, Professor Paul KS Chan

  290. Antiviral property and mechanisms of a sulphated polysaccharide from the brown alga Sargassum patens against Herpes simplex virus type 1

    Article • Phytomedicine, November 2006, Elsevier

    Professor Paul KS Chan

  291. Factors involved in the aerosol transmission of infection and control of ventilation in healthcare premises

    Article • Journal of Hospital Infection, October 2006, Elsevier

    Professor Paul KS Chan

  292. Extremely Low Exposure of a Community to Severe Acute Respiratory Syndrome Coronavirus: False Seropositivity due to Use of Bacterially Derived Antigens

    Article • Journal of Virology, September 2006, ASM Journals

    Professor Paul KS Chan

  293. The Large 386‐nt Deletion in SARS‐Associated Coronavirus: Evidence for Quasispecies?

    Article • The Journal of Infectious Diseases, September 2006, Oxford University Press (OUP)

    Professor Paul KS Chan

  294. Probable Intrafamilial Transmission of Coxsackievirus B3 With Vertical Transmission, Severe Early-Onset Neonatal Hepatitis, and Prolonged Viral RNA Shedding

    Article • PEDIATRICS, September 2006, American Academy of Pediatrics (AAP)

    Professor Paul KS Chan

  295. Airflows Around Oxygen Masks

    Article • CHEST Journal, September 2006, Elsevier

    Professor Paul KS Chan

  296. Fecal Viral Load and Norovirus-associated Gastroenteritis

    Article • Emerging Infectious Diseases, August 2006, Centers for Disease Control and Prevention (CDC)

    Professor Paul KS Chan

  297. The detection of human herpesvirus-8 DNA in plasma and peripheral blood mononuclear cells in adult patients with pityriasis rosea by polymerase chain reaction

    Article • Journal of the European Academy of Dermatology and Venereology, July 2006, Wiley

    Professor Paul KS Chan

  298. Innate and adaptive cellular immunity in flavivirus-naïve human recipients of a live-attenuated dengue serotype 3 vaccine produced in Vero cells (VDV3)

    Article • Vaccine, June 2006, Elsevier

    Professor Paul KS Chan

  299. Sapovirus detection by quantitative real-time RT-PCR in clinical stool specimens

    Article • Journal of Virological Methods, June 2006, Elsevier

    Professor Paul KS Chan

  300. Steroid-induced osteonecrosis in severe acute respiratory syndrome: a retrospective analysis of biochemical markers of bone metabolism and corticosteroid therapy

    Article • Pathology, June 2006, Elsevier

    Professor Paul KS Chan

  301. Anti–Severe Acute Respiratory Syndrome Coronavirus Immune Responses: The Role Played by Vγ9Vδ2 T Cells

    Article • The Journal of Infectious Diseases, May 2006, Oxford University Press (OUP)

    Dr Maria Rosaria Capobianchi, Professor Paul KS Chan

  302. Rapid control of norovirus gastroenteritis outbreak in an acute paediatric ward

    Article • Acta Paediatrica, May 2006, Wiley

    Professor Paul KS Chan

  303. Specific epitopes of the structural and hypothetical proteins elicit variable humoral responses in SARS patients

    Article • Journal of Clinical Pathology, February 2006, BMJ

    Professor Paul KS Chan

  304. Anti-SARS-CoV IgG response in relation to disease severity of severe acute respiratory syndrome

    Article • Journal of Clinical Virology, February 2006, Elsevier

    Professor Margaret Ip, Professor Paul KS Chan

  305. SARS: clinical presentation, transmission, pathogenesis and treatment options

    Article • Clinical Science, February 2006, Portland Press Ltd.

    Professor Paul KS Chan

  306. Chikungunya Fever, Hong Kong

    Article • January 2006, Centers for Disease Control and Prevention (CDC)

    Professor Paul KS Chan

  307. Hepatitis C virus genotype distribution among intravenous drug user and the general population in Hong Kong

    Article • Journal of Medical Virology, January 2006, Wiley

    Professor Paul KS Chan

  308. Cross-reactivity of antibody against SARS-coronavirus nucleocapsid protein with IL-11

    Article • Biochemical and Biophysical Research Communications, December 2005, Elsevier

    Professor Paul KS Chan

  309. Early Enhanced Expression of Interferon-Inducible Protein-10 (CXCL-10) and Other Chemokines Predicts Adverse Outcome in Severe Acute Respiratory Syndrome

    Article • Clinical Chemistry, December 2005, AACC

    Professor Paul KS Chan

  310. Risk Association between Human Leukocyte Antigen–A Allele and High‐Risk Human Papillomavirus Infection for Cervical Neoplasia in Chinese Women

    Article • The Journal of Infectious Diseases, November 2005, Oxford University Press (OUP)

    Professor Paul KS Chan

  311. In vivo functional characterization of the SARS-Coronavirus 3a protein in Drosophila

    Article • Biochemical and Biophysical Research Communications, November 2005, Elsevier

    Professor Paul KS Chan

  312. Biases in human papillomavirus genotype prevalence assessment associatedwith commonly used consensus primers

    Article • International Journal of Cancer, October 2005, Wiley

    Professor Margaret Ip, Professor Paul KS Chan

  313. A simple and rapid approach for screening of SARS-coronavirus genotypes: an evaluation study

    Article • BMC Infectious Diseases, October 2005, Springer Science + Business Media

    Professor Paul KS Chan

  314. HLA-B alleles, high-risk HPV infection and risk for cervical neoplasia in southern Chinese women

    Article • International Journal of Cancer, October 2005, Wiley

    Professor Paul KS Chan

  315. Influence of FcgammaRIIA and MBL polymorphisms on severe acute respiratory syndrome

    Article • Tissue Antigens, October 2005, Wiley

    Professor Paul KS Chan

  316. Experience of using convalescent plasma for severe acute respiratory syndrome among healthcare workers in a Taiwan hospital

    Article • Journal of Antimicrobial Chemotherapy, September 2005, Oxford University Press (OUP)

    Professor Paul KS Chan

  317. Human Parainfluenza Virus 4 Outbreak and the Role of Diagnostic Tests

    Article • Journal of Clinical Microbiology, September 2005, ASM Journals

    Professor Paul KS Chan

  318. Estimates of Rotavirus Disease Burden in Hong Kong: Hospital‐Based Surveillance

    Article • The Journal of Infectious Diseases, September 2005, Oxford University Press (OUP)

    Professor Paul KS Chan

  319. Hospital‐Based Study of the Economic Burden Associated with Rotavirus Diarrhea in Hong Kong

    Article • The Journal of Infectious Diseases, September 2005, Oxford University Press (OUP)

    Professor Paul KS Chan

  320. Prevention of Hepatitis B Virus Reactivation in Patients With Nasopharyngeal Carcinoma With Lamivudine

    Article • American Journal of Clinical Oncology, August 2005, Wolters Kluwer Health

    Professor Paul KS Chan

  321. Antibody Avidity Maturation during Severe Acute Respiratory Syndrome–Associated Coronavirus Infection

    Article • The Journal of Infectious Diseases, July 2005, Oxford University Press (OUP)

    Professor Paul KS Chan

  322. Detection and quantitation of human papillomavirus DNA in primary tumour and lymph nodes of patients with early stage cervical carcinoma

    Article • Journal of Clinical Virology, July 2005, Elsevier

    Professor Paul KS Chan

  323. Transmission of hepatitis B by human bite—Confirmation by detection of virus in saliva and full genome sequencing

    Article • Journal of Clinical Virology, July 2005, Elsevier

    Professor Paul KS Chan, Prof Henry LY Chan

  324. The 3a protein of severe acute respiratory syndrome-associated coronavirus induces apoptosis in Vero E6 cells

    Article • Journal of General Virology, July 2005, Society for General Microbiology

    Professor Paul KS Chan

  325. Serum neopterin for early assessment of severity of severe acute respiratory syndrome

    Article • Clinical Immunology, July 2005, Elsevier

    Professor Paul KS Chan

  326. Pityriasis rosea in pregnancy - specific diagnostic implications and management considerations

    Article • Australian and New Zealand Journal of Obstetrics and Gynaecology, June 2005, Wiley

    Professor Paul KS Chan

  327. Coronaviral hypothetical and structural proteins were found in the intestinal surface enterocytes and pneumocytes of severe acute respiratory syndrome (SARS)

    Article • Modern Pathology, May 2005, Nature

    Professor Paul KS Chan

  328. Precautions in ophthalmic practice in a hospital with a major acute SARS outbreak: an experience from Hong Kong

    Article • Eye, April 2005, Nature

    Professor Paul KS Chan

  329. Absence of association between angiotensin converting enzyme polymorphism and development of adult respiratory distress syndrome in patients with severe acute respiratory syndrome: a case control study

    Article • BMC Infectious Diseases, April 2005, Springer Science + Business Media

    Professor Paul KS Chan

  330. ABO Blood Group and Susceptibility to Severe Acute Respiratory Syndrome

    Article • JAMA, March 2005, American Medical Association (AMA)

    Professor Paul KS Chan

  331. Longitudinally Profiling Neutralizing Antibody Response to SARS Coronavirus with Pseudotypes

    Article • Emerging Infectious Diseases, March 2005, Centers for Disease Control and Prevention (CDC)

    Professor Nigel James Temperton, Professor Paul KS Chan

  332. Clinical significance of hepatic derangement in severe acute respiratory syndrome

    Article • World Journal of Gastroenterology, January 2005, Baishideng Publishing Group Co., Limited (formerly WJG Press)

    Professor Paul KS Chan, Prof Henry LY Chan

  333. Tracing SARS-Coronavirus Variant with Large Genomic Deletion

    Article • Emerging Infectious Diseases, January 2005, Centers for Disease Control and Prevention (CDC)

    Professor Paul KS Chan

  334. Effects of early corticosteroid treatment on plasma SARS-associated Coronavirus RNA concentrations in adult patients

    Article • Journal of Clinical Virology, December 2004, Elsevier

    Professor Paul KS Chan

  335. Use of lamivudine to prevent hepatitis B virus reactivation during chemotherapy in breast cancer patients

    Article • Breast Cancer Research and Treatment, December 2004, Springer Science + Business Media

    Professor Paul KS Chan

  336. Increased prevalence of squamous intraepithelial lesions in systemic lupus erythematosus: Association with human papillomavirus infection

    Article • Arthritis & Rheumatism, November 2004, Wiley

    Professor Paul KS Chan

  337. Evaluation of a peptide-based enzyme immunoassay for anti-SARS coronavirus IgG antibody

    Article • Journal of Medical Virology, October 2004, Wiley

    Professor Paul KS Chan

  338. ACE2 Gene Polymorphisms Do Not Affect Outcome of Severe Acute Respiratory Syndrome

    Article • Clinical Chemistry, September 2004, AACC

    Professor Paul KS Chan

  339. Antiviral property and mode of action of a sulphated polysaccharide from Sargassum patens against herpes simplex virus type 2

    Article • International Journal of Antimicrobial Agents, September 2004, Elsevier

    Professor Paul KS Chan

  340. Hematological findings in SARS patients and possible mechanisms (Review)

    Article • International Journal of Molecular Medicine, August 2004, Spandidos Publications

    Professor Paul KS Chan

  341. Antibody Response of Patients with Severe Acute Respiratory Syndrome (SARS) Targets the Viral Nucleocapsid

    Article • The Journal of Infectious Diseases, July 2004, Oxford University Press (OUP)

    Professor Paul KS Chan

  342. Tears and conjunctival scrapings for coronavirus in patients with SARS

    Article • British Journal of Ophthalmology, July 2004, BMJ

    Professor Paul KS Chan

  343. Retrospective comparison of convalescent plasma with continuing high-dose methylprednisolone treatment in SARS patients

    Article • Clinical Microbiology and Infection, July 2004, Elsevier

    Professor Paul KS Chan

  344. Seroprevalence of Antibody to Severe Acute Respiratory Syndrome (SARS)-Associated Coronavirus among Health Care Workers in SARS and Non-SARS Medical Wards

    Article • Clinical Infectious Diseases, June 2004, Oxford University Press (OUP)

    Professor Paul KS Chan

  345. Diagnostic Criteria during SARS Outbreak in Hong Kong

    Article • Emerging Infectious Diseases, June 2004, Centers for Disease Control and Prevention (CDC)

    Professor Paul KS Chan

  346. Synthetic Peptide Studies on the Severe Acute Respiratory Syndrome (SARS) Coronavirus Spike Glycoprotein: Perspective for SARS Vaccine Development

    Article • Clinical Chemistry, June 2004, AACC

    Professor Paul KS Chan

  347. Asymmetric periflexural exanthem in an adult

    Article • Clinical and Experimental Dermatology, May 2004, Wiley

    Professor Paul KS Chan

  348. Immunogenicity of a two-dose regime of varicella vaccine in children with cancers

    Article • European Journal Of Haematology, May 2004, Wiley

    Professor Paul KS Chan

  349. Severe acute respiratory syndrome: report of treatment and outcome after a major outbreak

    Article • Thorax, May 2004, BMJ

    Professor Paul KS Chan

  350. The Spectrum of Severe Acute Respiratory Syndrome–Associated Coronavirus Infection

    Article • Annals of Internal Medicine, April 2004, American College of Physicians

    Professor Paul KS Chan

  351. Retrospective analysis of liver function derangement in severe acute respiratory syndrome

    Article • The American Journal of Medicine, April 2004, Elsevier

    Professor Paul KS Chan, Prof Henry LY Chan

  352. Serum LD1 isoenzyme and blood lymphocyte subsets as prognostic indicators for severe acute respiratory syndrome

    Article • Journal of Internal Medicine, April 2004, Wiley

    Professor Paul KS Chan

  353. Molecular Evolution of the SARS Coronavirus During the Course of the SARS Epidemic in China

    Article • Science, March 2004, American Association for the Advancement of Science

    Professor Paul KS Chan

  354. Comprehensive analysis of risk factors associating with Hepatitis B virus (HBV) reactivation in cancer patients undergoing cytotoxic chemotherapy

    Article • British Journal of Cancer, March 2004, Nature

    Professor Paul KS Chan, Prof Benny CY Zee

  355. Immunofluorescence Assay for Serologic Diagnosis of SARS

    Article • Emerging Infectious Diseases, March 2004, Centers for Disease Control and Prevention (CDC)

    Professor Paul KS Chan

  356. Human Metapneumovirus-associated Atypical Pneumonia and SARS

    Article • Emerging Infectious Diseases, March 2004, Centers for Disease Control and Prevention (CDC)

    Professor Paul KS Chan

  357. Resistance to apoptosis of HPV 16-infected laryngeal cancer cells is associated with decreased Bak and increased Bcl-2 expression

    Article • Cancer Letters, March 2004, Elsevier

    Professor Paul KS Chan

  358. Pulmonary pathological features in coronavirus associated severe acute respiratory syndrome (SARS)

    Article • Journal of Clinical Pathology, March 2004, BMJ

    Professor Paul KS Chan

  359. Lamivudine for the Prevention of Hepatitis B Virus Reactivation in Hepatitis B s-Antigen Seropositive Cancer Patients Undergoing Cytotoxic Chemotherapy

    Article • Journal of Clinical Oncology, March 2004, American Society of Clinical Oncology (ASCO)

    Professor Paul KS Chan, Prof Benny CY Zee

  360. Risk factors and clinical consequences of human herpesvirus 7 infection in paediatric haematopoietic stem cell transplant recipients

    Article • Journal of Medical Virology, February 2004, Wiley

    Professor Paul KS Chan

  361. Cluster of SARS among Medical Students Exposed to Single Patient, Hong Kong

    Article • Emerging Infectious Diseases, February 2004, Centers for Disease Control and Prevention (CDC)

    Professor Paul KS Chan

  362. Tissue and cellular tropism of the coronavirus associated with severe acute respiratory syndrome: an in-situ hybridization study of fatal cases

    Article • The Journal of Pathology, January 2004, Wiley

    Professor Paul KS Chan

  363. Excess hospital admissions for pneumonia, chronic obstructive pulmonary disease, and heart failure during influenza seasons in Hong Kong

    Article • Journal of Medical Virology, January 2004, Wiley

    Dr Pak-Leung Ho, Professor Paul KS Chan

  364. Evaluation of a recombinant nucleocapsid protein-based assay for Anti-SARS-CoV IgG detection

    Article • Journal of Medical Virology, January 2004, Wiley

    Professor Paul KS Chan

  365. Persistent infection of SARS coronavirus in colonic cells in vitro

    Article • Journal of Medical Virology, January 2004, Wiley

    Professor Paul KS Chan

  366. Reduction of double-stranded RNA-activated protein kinase in hepatocellular carcinoma associated with hepatitis B virus

    Article • Journal of Medical Virology, January 2004, Wiley

    Professor Paul KS Chan

  367. High hepatitis B virus (HBV) DNA viral load is an important risk factor for HBV reactivation in breast cancer patients undergoing cytotoxic chemotherapy

    Article • Journal of Viral Hepatitis, January 2004, Wiley

    Professor Paul KS Chan, Prof Benny CY Zee

  368. Detection of SARS Coronavirus in Plasma by Real-Time RT-PCR

    Article • New England Journal of Medicine, December 2003, New England Journal of Medicine (NEJM/MMS)

    Professor Paul KS Chan

  369. A real-time PCR for SARS-coronavirus incorporating target gene pre-amplification

    Article • Biochemical and Biophysical Research Communications, December 2003, Elsevier

    Professor Paul KS Chan

  370. Detection of SARS Coronavirus RNA in the Cerebrospinal Fluid of a Patient with Severe Acute Respiratory Syndrome

    Article • Clinical Chemistry, November 2003, AACC

    Professor Paul KS Chan

  371. Severe Acute Respiratory Syndrome–associated Coronavirus Infection

    Article • Emerging Infectious Diseases, November 2003, Centers for Disease Control and Prevention (CDC)

    Professor Margaret Ip, Professor Paul KS Chan

  372. Genomic characterisation of the severe acute respiratory syndrome coronavirus of Amoy Gardens outbreak in Hong Kong

    Article • The Lancet, November 2003, Elsevier

    Professor Paul KS Chan

  373. Enteric involvement of severe acute respiratory syndrome-associated coronavirus infection1 1The authors thank Man-yee Yung, Sara Fung, Dr. Bonnie Kwan, and Dr. Thomas Li for their help in retrieving patient information.

    Article • Gastroenterology, October 2003, Elsevier

    Professor Paul KS Chan, Prof Henry LY Chan

  374. Infants Born to Mothers With Severe Acute Respiratory Syndrome

    Article • PEDIATRICS, October 2003, American Academy of Pediatrics (AAP)

    Professor Paul KS Chan

  375. Genetic variation of glycoproteins B and H of human herpesvirus 7 in Hong Kong

    Article • Journal of Medical Virology, September 2003, Wiley

    Professor Paul KS Chan

  376. Human Metapneumovirus Detection in Patients with Severe Acute Respiratory Syndrome

    Article • Emerging Infectious Diseases, September 2003, Centers for Disease Control and Prevention (CDC)

    Professor Paul KS Chan

  377. Fatal outcome of SARS in a patient with reactivation of chronic hepatitis B

    Article • The American Journal of Medicine, September 2003, Elsevier

    Professor Paul KS Chan, Prof Henry LY Chan

  378. A Hong Kong family with respiratory illness

    Article • The Lancet, July 2003, Elsevier

    Professor Margaret Ip, Professor Paul KS Chan

  379. Newly discovered coronavirus as the primary cause of severe acute respiratory syndrome

    Article • The Lancet, July 2003, Elsevier

    Professor Paul KS Chan

  380. Haematological manifestations in patients with severe acute respiratory syndrome: retrospective analysis

    Article • BMJ, June 2003, BMJ

    Professor Paul KS Chan

  381. Hepatitis B virus reactivation in breast cancer patients receiving cytotoxic chemotherapy: A prospective study

    Article • Journal of Medical Virology, June 2003, Wiley

    Professor Paul KS Chan

  382. A Major Outbreak of Severe Acute Respiratory Syndrome in Hong Kong

    Article • New England Journal of Medicine, May 2003, New England Journal of Medicine (NEJM/MMS)

    Professor Paul KS Chan

  383. Clinical presentations and outcome of severe acute respiratory syndrome in children

    Article • The Lancet, May 2003, Elsevier

    Professor Paul KS Chan

  384. Re: Hormonal Markers and Hepatitis B Virus-Related Hepatocellular Carcinoma Risk: A Nested Case-Control Study Among Men

    Article • JNCI Journal of the National Cancer Institute, April 2003, Oxford University Press (OUP)

    Professor Paul KS Chan

  385. Hypermethylation of the tumor suppressor gene RASSFIA and frequent concomitant loss of heterozygosity at 3p21 in cervical cancers

    Article • International Journal of Cancer, March 2003, Wiley

    Professor Paul KS Chan

  386. Isolation and characterization of a sulfated polysaccharide from the brown alga Sargassum patens and determination of its anti-herpes activity

    Article • Biochemistry and Cell Biology, January 2003, Canadian Science Publishing

    Professor Paul KS Chan

  387. Human Papillomavirus Type 16 Intratypic Variant Infection and Risk for Cervical Neoplasia in Southern China

    Article • The Journal of Infectious Diseases, September 2002, Oxford University Press (OUP)

    Professor Paul KS Chan

  388. Association of Human Papillomavirus Type 58 Variant With the Risk of Cervical Cancer

    Article • JNCI Journal of the National Cancer Institute, August 2002, Oxford University Press (OUP)

    Professor Paul KS Chan

  389. Genotype spectrum of cervical human papillomavirus infection among sexually transmitted disease clinic patients in Hong Kong

    Article • Journal of Medical Virology, August 2002, Wiley

    Professor Paul KS Chan

  390. Human herpesvirus-6 encephalitis after unrelated umbilical cord blood transplant in children

    Article • Bone Marrow Transplantation, July 2002, Nature

    Professor Paul KS Chan

  391. Prevalence and genotype distribution of cervical human papillomavirus infection: Comparison between pregnant women and non-pregnant controls

    Article • Journal of Medical Virology, July 2002, Wiley

    Professor Paul KS Chan

  392. Interferon and ribavirin as frontline treatment for chronic hepatitis C infection in thalassaemia major

    Article • British Journal of Haematology, June 2002, Wiley

    Professor Paul KS Chan

  393. Outbreak of Avian Influenza A(H5N1) Virus Infection in Hong Kong in 1997

    Article • Clinical Infectious Diseases, May 2002, Oxford University Press (OUP)

    Professor Paul KS Chan

  394. Case report: Human herpesvirus 7 associated fatal encephalitis in a peripheral blood stem cell transplant recipient

    Article • Journal of Medical Virology, February 2002, Wiley

    Professor Paul KS Chan

  395. Determinants of Cervical Human Papillomavirus Infection: Differences between High‐ and Low‐Oncogenic Risk Types

    Article • The Journal of Infectious Diseases, January 2002, Oxford University Press (OUP)

    Professor Paul KS Chan

  396. Hepatitis B virus reactivation during cytotoxic chemotherapy‐enhanced viral replication precedes overt hepatitis

    Article • Journal of Medical Virology, November 2001, Wiley

    Professor Paul KS Chan, Prof Henry LY Chan

  397. Decreased expression of Bid in human hepatocellular carcinoma is related to hepatitis B virus X protein

    Article • European Journal of Cancer, September 2001, Elsevier

    Professor Paul KS Chan

  398. Prevalence and genotype distribution of TT virus in various specimen types from thalassaemic patients

    Article • Journal of Viral Hepatitis, July 2001, Wiley

    Professor Paul KS Chan

  399. Evaluation of extraction methods from paraffin wax embedded tissues for PCR amplification of human and viral DNA

    Article • Journal of Clinical Pathology, May 2001, BMJ

    Professor Paul KS Chan

  400. High Carriage Rate of TT Virus in the Cervices of Pregnant Women

    Article • Clinical Infectious Diseases, May 2001, Oxford University Press (OUP)

    Professor Paul KS Chan

  401. Association of human beta-herpesviruses with the development of cervical cancer: bystanders or cofactors

    Article • Journal of Clinical Pathology, January 2001, BMJ

    Professor Paul KS Chan

  402. Prevalence and distribution of human herpesvirus 6 variants A and B in adult human brain

    Article • Journal of Medical Virology, January 2001, Wiley

    Professor Paul KS Chan

  403. Clearance of TT Virus After Allogeneic Bone Marrow Transplantation

    Article • January 2001, Wolters Kluwer Health

    Professor Paul KS Chan

  404. Sequence variations of precore/core and precore promoter regions of hepatitis B virus in patients with or without viral reactivation during cytotoxic chemotherapy

    Article • Journal of Viral Hepatitis, November 2000, Wiley

    Professor Paul KS Chan

  405. Rapid identification of medically important Candida to species level by polymerase chain reaction and single-strand conformational polymorphism

    Article • Diagnostic Microbiology and Infectious Disease, October 2000, Elsevier

    Professor Margaret Ip, Professor Paul KS Chan

  406. Hepatitis B virus reactivation in patients undergoing cytotoxic chemotherapy for solid tumours: Precore/core mutations may play an important role

    Article • Journal of Medical Virology, March 2000, Wiley

    Professor Paul KS Chan

  407. Incidence, risk factors and outcome of varicella-zoster virus infection in children after haematopoietic stem cell transplantation

    Article • Bone Marrow Transplantation, February 2000, Nature

    Professor Paul KS Chan

  408. Risk of Influenza A (H5N1) Infection among Health Care Workers Exposed to Patients with Influenza A (H5N1), Hong Kong

    Article • The Journal of Infectious Diseases, January 2000, Oxford University Press (OUP)

    Professor Paul KS Chan

  409. Frequency of hepatitis B virus reactivation in cancer patients undergoing cytotoxic chemotherapy: A prospective study of 626 patients with identification of risk factors

    Article • Journal of Medical Virology, January 2000, Wiley

    Professor Paul KS Chan, Prof Benny CY Zee

  410. Presence of human herpesviruses 6, 7, and 8 DNA sequences in normal brain tissue

    Article • Journal of Medical Virology, December 1999, Wiley

    Professor Margaret Ip, Professor Paul KS Chan

  411. Parvovirus B19 infection causing red cell aplasia in renal transplantation on tacrolimus

    Article • American Journal of Kidney Diseases, December 1999, Elsevier

    Professor Paul KS Chan

  412. Detection of Human Herpesvirus 8 in Cervical Cells of Chinese Women with Abnormal Papanicolaou Smears

    Article • Clinical Infectious Diseases, December 1999, Oxford University Press (OUP)

    Professor Paul KS Chan

  413. Lamivudine in the treatment of hepatitis B virus reactivation during cytotoxic chemotherapy

    Article • Journal of Medical Virology, November 1999, Wiley

    Professor Paul KS Chan

  414. Epidemiology of respiratory syncytial virus infection among paediatric patients in Hong Kong: seasonality and disease impact

    Article • Epidemiology and Infection, October 1999, Cambridge University Press

    Professor Paul KS Chan

  415. High prevalence of human papillomavirus type 58 in Chinese women with cervical cancer and precancerous lesions

    Article • Journal of Medical Virology, October 1999, Wiley

    Professor Paul KS Chan

  416. Detection of human herpesviruses 6 and 7 genomic sequences in brain tumours

    Article • Journal of Clinical Pathology, August 1999, BMJ

    Professor Paul KS Chan

  417. Rubella immune status among healthcare workers in the Department of Obstetrics and Gynaecology of a regional hospital in Hong Kong: the need for a vaccination policy

    Article • Journal of Hospital Infection, July 1999, Elsevier

    Professor Paul KS Chan

  418. Rotavirus infection in Hong Kong: epidemiology and estimates of disease burden

    Article • Epidemiology and Infection, June 1998, Cambridge University Press

    Professor Paul KS Chan

  419. Clinical features and rapid viral diagnosis of human disease associated with avian influenza A H5N1 virus

    Article • The Lancet, February 1998, Elsevier

    Professor Paul KS Chan

  420. Human herpesvirus-6 and human herpesvirus-7 infections in bone marrow transplant recipients

    Article • Journal of Medical Virology, November 1997, Wiley

    Professor Paul KS Chan

  421. Congenital infection by human cytomegalovirus with a 65 bp deletion in the morphological transforming region II

    Article • Archives of Virology, March 1993, Springer Science + Business Media

    Professor Paul KS Chan