All Stories

  1. General guidelines for biomedical software development

    Article • F1000Research, July 2017, Faculty of 1000, Ltd.

    Mr Rafael C Jimenez, Dr Niklas U Blomberg

  2. Identifiers for the 21st century: How to design, provision, and reuse persistent identifiers to maximize utility and impact of life science data

    Article • PLoS Biology, June 2017, PLOS

    Mr Rafael C Jimenez, Dr Niklas U Blomberg

  3. Bridging the translational innovation gap through good biomarker practice

    Article • Nature Reviews Drug Discovery, April 2017, Springer Science + Business Media

    Dr Niklas U Blomberg

  4. Identifiers for the 21st century: How to design, provision, and reuse persistent identifiers to maximize utility and impact of life science data

    Article • March 2017, Cold Spring Harbor Laboratory Press

    Dr Niklas U Blomberg

  5. General guidelines for biomedical software development

    Article • F1000Research, March 2017, Faculty of 1000, Ltd.

    Dr Niklas U Blomberg, José Luis Oliveira, Luís António Bastião Silva, Mr Rafael C Jimenez

  6. Identifying ELIXIR Core Data Resources

    Article • F1000Research, March 2017, Faculty of 1000, Ltd.

    Dr Christine Durinx, Dr Niklas U Blomberg

  7. Data management: A global coalition to sustain core data

    Article • Nature, March 2017, Springer Science + Business Media

    Dr Niklas U Blomberg

  8. TOWARDS COORDINATED INTERNATIONAL SUPPORT OF CORE DATA RESOURCES FOR THE LIFE SCIENCES

    Article • February 2017, Cold Spring Harbor Laboratory Press

    Dr Niklas U Blomberg

  9. Erratum to: Making sense of big data in health research: towards an EU action plan

    Article • Genome Medicine, November 2016, Springer Science + Business Media

    Dr Niklas U Blomberg

  10. Identifying ELIXIR Core Data Resources

    Article • F1000Research, September 2016, Faculty of 1000, Ltd.

    Dr Niklas U Blomberg, Christine Durinx, Dr Christine Durinx

  11. Making sense of big data in health research: Towards an EU action plan

    Article • Genome Medicine, June 2016, Springer Science + Business Media

    Professor Werner Muller, DR Juan Antonio Vizcaino, Dr Christoph Bock, Dr Niklas U Blomberg

  12. The ELIXIR channel in F1000Research

    Article • F1000Research, May 2016, Faculty of 1000, Ltd.

    Dr Niklas U Blomberg, Prof Barend Mons

  13. The FAIR Guiding Principles for scientific data management and stewardship

    Article • Scientific Data, March 2016, Springer Science + Business Media

    Dr Niklas U Blomberg, Gaby Appleton, Luiz Olavo Bonino da Silva Santos, Professor Chris Evelo

  14. Patterns of database citation

    Article • F1000Research, February 2016, Faculty of 1000, Ltd.

    Dr Niklas U Blomberg, Dr Alex Bateman, Mr Francois Blaise ATFB Alako Tadontsop

  15. The ELIXIR channel in F1000Research

    Article • F1000Research, December 2015, Faculty of 1000, Ltd.

    Dr Niklas U Blomberg, Prof Barend Mons

  16. A Quick Guide for Building a Successful Bioinformatics Community

    Article • PLoS Computational Biology, February 2015, PLOS

    Dr Niklas U Blomberg

  17. CHAPTER 13. Bioinformatics for Medicinal Chemistry

    Article • January 2015, Royal Society of Chemistry

    Dr Niklas U Blomberg

  18. Mining Molecular Pharmacological Effects from Biomedical Text: a Case Study for Eliciting Anti-Obesity/Diabetes Effects of Chemical Compounds

    Article • Molecular Informatics, May 2014, Wiley

    Dr Niklas U Blomberg

  19. The Scientific Requirements for Integrating chemistry and biology data on the Open PHACTS platform

    Article • December 2013, Taylor & Francis

    Dr Antony John Williams, Dr Niklas U Blomberg

  20. Big pharma screening collections: more of the same or unique libraries? The AstraZeneca–Bayer Pharma AG case

    Article • Drug Discovery Today, October 2013, Elsevier

    Dr Niklas U Blomberg

  21. Scientific competency questions as the basis for semantically enriched open pharmacological space

    Article • Drug Discovery Today, September 2013, Elsevier

    Dr Antony John Williams, Dr Niklas U Blomberg

  22. An outline of what Open PHACTS is

    Article • Drug Discovery Today, November 2012, Elsevier

    Dr Antony John Williams, Dr Niklas U Blomberg, Professor Chris Evelo

  23. Theoretical Studies of Chemical Reactivity of Metabolically Activated Forms of Aromatic Amines toward DNA

    Article • Chemical Research in Toxicology, October 2012, American Chemical Society (ACS)

    Dr Niklas U Blomberg

  24. SARConnect: A Tool to Interrogate the Connectivity Between Proteins, Chemical Structures and Activity Data

    Article • Molecular Informatics, August 2012, Wiley

    Dr Christopher Southan, Dr Niklas U Blomberg

  25. Taking Open Innovation to the Molecular Level - Strengths and Limitations

    Article • Molecular Informatics, August 2012, Wiley

    Dr Niklas U Blomberg

  26. A comparative analysis of the molecular topologies for drugs, clinical candidates, natural products, human metabolites and general bioactive compounds

    Article • MedChemComm, January 2012, Royal Society of Chemistry

    Dr Niklas U Blomberg

  27. Strategies to improve in vivo toxicology outcomes for basic candidate drug molecules

    Article • Bioorganic & Medicinal Chemistry Letters, October 2011, Elsevier

    Dr Niklas U Blomberg

  28. Design and synthesis of macrocyclic indoles targeting blood coagulation cascade Factor XIa

    Article • Bioorganic & Medicinal Chemistry Letters, December 2010, Elsevier

    Dr Niklas U Blomberg

  29. Combinatorial Library Design from Reagent Pharmacophore Fingerprints

    Article • October 2010, Springer Science + Business Media

    Dr Niklas U Blomberg

  30. Physicochemical property profiles of marketed drugs, clinical candidates and bioactive compounds

    Article • Bioorganic & Medicinal Chemistry Letters, December 2009, Elsevier

    Dr Niklas U Blomberg

  31. Comparative binding energy analysis for binding affinity and target selectivity prediction

    Article • Proteins Structure Function and Bioinformatics, August 2009, Wiley

    Dr Niklas U Blomberg

  32. Designing a Combinatorial Library by Using Reagent Pharmacophore Fingerprint

    Article • QSAR & Combinatorial Science, April 2009, Wiley

    Dr Niklas U Blomberg

  33. ProSAR: A New Methodology for Combinatorial Library Design

    Article • Journal of Chemical Information and Modeling, March 2009, American Chemical Society (ACS)

    Dr Niklas U Blomberg

  34. Design of compound libraries for fragment screening

    Article • Journal of Computer-Aided Molecular Design, March 2009, Springer Science + Business Media

    Dr Niklas U Blomberg

  35. An Integrated Approach to Fragment-Based Lead Generation:Philosophy, Strategy and Case Studies from AstraZenecas Drug Discovery Programmes

    Article • Current Topics in Medicinal Chemistry, August 2007, Bentham Science Publishers

    Dr Niklas U Blomberg

  36. Structure-based organic synthesis of unnatural aeruginosin hybrids as potent inhibitors of thrombin

    Article • Bioorganic & Medicinal Chemistry Letters, June 2007, Elsevier

    Dr Niklas U Blomberg

  37. Development, interpretation and temporal evaluation of a global QSAR of hERG electrophysiology screening data

    Article • Journal of Computer-Aided Molecular Design, March 2007, Springer Science + Business Media

    Dr Niklas U Blomberg

  38. Total Synthesis and Structural Confirmation of Chlorodysinosin A.

    Article • ChemInform, January 2007, Wiley

    Dr Niklas U Blomberg

  39. Total Synthesis and Structural Confirmation of Chlorodysinosin A  [ J. Am. Chem. Soc. 2006 , 128 , 10491−10495]. 

    Article • Journal of the American Chemical Society, September 2006, American Chemical Society (ACS)

    Dr Niklas U Blomberg

  40. Total Synthesis and Structural Confirmation of Chlorodysinosin A

    Article • Journal of the American Chemical Society, August 2006, American Chemical Society (ACS)

    Dr Niklas U Blomberg

  41. Multifingerprint Based Similarity Searches for Targeted Class Compound Selection.

    Article • ChemInform, July 2006, Wiley

    Dr Niklas U Blomberg

  42. Multifingerprint Based Similarity Searches for Targeted Class Compound Selection

    Article • Journal of Chemical Information and Modeling, May 2006, American Chemical Society (ACS)

    Dr Niklas U Blomberg

  43. Structure of the PPARα and -γ Ligand Binding Domain in Complex with AZ 242; Ligand Selectivity and Agonist Activation in the PPAR Family

    Article • Structure, August 2001, Elsevier

    Dr Niklas U Blomberg

  44. Structure of a PH Domain from the C. elegans Muscle Protein UNC-89 Suggests a Novel Function

    Article • Structure, October 2000, Elsevier

    Dr Niklas U Blomberg

  45. Article • Journal of Biomolecular NMR, January 2000, Springer Science + Business Media

    Dr Niklas U Blomberg

  46. Classification of protein sequences by homology modeling and quantitative analysis of electrostatic similarity

    Article • Proteins Structure Function and Bioinformatics, November 1999, Wiley

    Dr Niklas U Blomberg

  47. The PH superfold: a structural scaffold for multiple functions

    Article • Trends in Biochemical Sciences, November 1999, Elsevier

    Dr Niklas U Blomberg

  48. Article • Journal of Biomolecular NMR, January 1999, Springer Science + Business Media

    Dr Niklas U Blomberg

  49. Functional diversity of PH domains: an exhaustive modelling study

    Article • Folding and Design, December 1997, Elsevier

    Dr Niklas U Blomberg

  50. Internal repeats in the BRCA2 protein sequence

    Article • Nature Genetics, May 1996, Nature

    Dr Niklas U Blomberg